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Conserved domains on  [gi|21355389|ref|NP_649828|]
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uncharacterized protein Dmel_CG8223, isoform A [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 256-351 9.44e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.07  E-value: 9.44e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355389 256 GSLQLAWEILEAAAQIFsrqglsglPYLAEVQTELANIEFENGILEAAREDYEKALKIHGElptrnrraLAELHYKIGLT 335
Cdd:COG3914  92 GRYEEALALYRRALALN--------PDNAEALFNLGNLLLALGRLEEALAALRRALALNPD--------FAEAYLNLGEA 155

                        90
                ....*....|....*.
gi 21355389 336 YLMQQLNKEGATALRQ 351
Cdd:COG3914 156 LRRLGRLEEAIAALRR 171
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 256-351 9.44e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.07  E-value: 9.44e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355389 256 GSLQLAWEILEAAAQIFsrqglsglPYLAEVQTELANIEFENGILEAAREDYEKALKIHGElptrnrraLAELHYKIGLT 335
Cdd:COG3914  92 GRYEEALALYRRALALN--------PDNAEALFNLGNLLLALGRLEEALAALRRALALNPD--------FAEAYLNLGEA 155

                        90
                ....*....|....*.
gi 21355389 336 YLMQQLNKEGATALRQ 351
Cdd:COG3914 156 LRRLGRLEEAIAALRR 171
TPR_11 pfam13414
TPR repeat;
291-340 5.25e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.45  E-value: 5.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 21355389   291 ANIEFENGILEAAREDYEKALKIhgelptrnRRALAELHYKIGLTYLMQQ 340
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKL--------DPDNPEAYYNLGLAYYKLG 42
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 256-351 9.44e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.07  E-value: 9.44e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21355389 256 GSLQLAWEILEAAAQIFsrqglsglPYLAEVQTELANIEFENGILEAAREDYEKALKIHGElptrnrraLAELHYKIGLT 335
Cdd:COG3914  92 GRYEEALALYRRALALN--------PDNAEALFNLGNLLLALGRLEEALAALRRALALNPD--------FAEAYLNLGEA 155

                        90
                ....*....|....*.
gi 21355389 336 YLMQQLNKEGATALRQ 351
Cdd:COG3914 156 LRRLGRLEEAIAALRR 171
TPR_11 pfam13414
TPR repeat;
291-340 5.25e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.45  E-value: 5.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 21355389   291 ANIEFENGILEAAREDYEKALKIhgelptrnRRALAELHYKIGLTYLMQQ 340
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKL--------DPDNPEAYYNLGLAYYKLG 42
TPR_12 pfam13424
Tetratricopeptide repeat;
282-352 3.55e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.21  E-value: 3.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21355389   282 YLAEVQTELANIEFENGILEAAREDYEKALKIHGELPTRNRRALAELHYKIGLTYLMQQLNKEGATALRQS 352
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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