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Conserved domains on  [gi|45550712|ref|NP_649797|]
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uncharacterized protein Dmel_CG9684 [Drosophila melanogaster]

Protein Classification

tudor domain-containing protein( domain architecture ID 12026459)

tudor domain-containing protein adopts a beta-barrel-like structure and may bind to proteins with dimethylated arginine or lysine residues, or to methylated histone tails to facilitate protein-protein interactions; similar to Caenorhabditis elegans protein tag-250

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TUDOR pfam00567
Tudor domain;
136-250 1.41e-15

Tudor domain;


:

Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 73.16  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45550712   136 SGAMVYITDFISSNRCYIRDasESAERAFDEVCKKVNTIATLLPR---IKNPPPNRLCLVHFNGMYVRAKM-CKKLREVS 211
Cdd:pfam00567   1 STIDVVVSHIESPSTFYIQP--KSDSKKLEKLTEELQEYYASKPPeslPPAVGDGCVAAFSEDGKWYRAKItESLDDGLV 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 45550712   212 HLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKN 250
Cdd:pfam00567  79 EVLFIDYGNTETVPLSDLRPLPPELESLPPQAIKCQLAG 117
zf-MYND pfam01753
MYND finger;
20-55 2.85e-09

MYND finger;


:

Pssm-ID: 460312  Cd Length: 39  Bit Score: 52.81  E-value: 2.85e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 45550712    20 CVHCANAAERV--CQRCGD-FYCSKHCQRQDWLRHRYIC 55
Cdd:pfam01753   1 CAVCGKEALKLlrCSRCKSvYYCSKECQKADWPYHKKEC 39
TUDOR super family cl26991
Tudor domain;
519-580 1.04e-06

Tudor domain;


The actual alignment was detected with superfamily member pfam00567:

Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 47.73  E-value: 1.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45550712   519 EPYKPVVREYVLARF--EGSWYRGKveqiIVVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:pfam00567  44 ESLPPAVGDGCVAAFseDGKWYRAK----ITESLDDGLVEVLFIDYGNTETVPLSDLRPLPPEL 103
 
Name Accession Description Interval E-value
TUDOR pfam00567
Tudor domain;
136-250 1.41e-15

Tudor domain;


Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 73.16  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45550712   136 SGAMVYITDFISSNRCYIRDasESAERAFDEVCKKVNTIATLLPR---IKNPPPNRLCLVHFNGMYVRAKM-CKKLREVS 211
Cdd:pfam00567   1 STIDVVVSHIESPSTFYIQP--KSDSKKLEKLTEELQEYYASKPPeslPPAVGDGCVAAFSEDGKWYRAKItESLDDGLV 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 45550712   212 HLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKN 250
Cdd:pfam00567  79 EVLFIDYGNTETVPLSDLRPLPPELESLPPQAIKCQLAG 117
zf-MYND pfam01753
MYND finger;
20-55 2.85e-09

MYND finger;


Pssm-ID: 460312  Cd Length: 39  Bit Score: 52.81  E-value: 2.85e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 45550712    20 CVHCANAAERV--CQRCGD-FYCSKHCQRQDWLRHRYIC 55
Cdd:pfam01753   1 CAVCGKEALKLlrCSRCKSvYYCSKECQKADWPYHKKEC 39
TUDOR pfam00567
Tudor domain;
519-580 1.04e-06

Tudor domain;


Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 47.73  E-value: 1.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45550712   519 EPYKPVVREYVLARF--EGSWYRGKveqiIVVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:pfam00567  44 ESLPPAVGDGCVAAFseDGKWYRAK----ITESLDDGLVEVLFIDYGNTETVPLSDLRPLPPEL 103
Tudor_TDRD11 cd20433
Tudor domain found in Tudor domain-containing protein 11 (TDRD11) and similar proteins; TDRD11, ...
 520-581 1.85e-06

Tudor domain found in Tudor domain-containing protein 11 (TDRD11) and similar proteins; TDRD11, also called Staphylococcal nuclease domain-containing protein 1 (SND1), 100 kDa coactivator, EBNA2 coactivator p100, or p100 co-activator, is a multifunctional protein that is reportedly associated with different types of RNA molecules, including mRNA, miRNA, pre-miRNA, and dsRNA. It has been implicated in a number of biological processes in eukaryotic cells, including the cell cycle, DNA damage repair, proliferation, and apoptosis. TDRD11 is overexpressed in multiple cancers and functions as an oncogene. It contains multiple Staphylococcal nuclease (SN) domains and a C-terminal Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410504 [Multi-domain]  Cd Length: 84  Bit Score: 46.14  E-value: 1.85e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45550712 520 PYKPVVREYVLARFE--GSWYRGKVEQIivvpRQQTKYRVMYLDYTNVEDITEMDIRRYPLDFT 581
Cdd:cd20433  25 SYTPRKGDLCAAKFVedGEWYRAKVEKV----EGDKKVHVLYIDYGNREVLPSTRLAALPPAFS 84
TUDOR smart00333
Tudor domain; Domain of unknown function present in several RNA-binding proteins. 10 copies in ...
 521-580 6.53e-06

Tudor domain; Domain of unknown function present in several RNA-binding proteins. 10 copies in the Drosophila Tudor protein. Initial proposal that the survival motor neuron gene product contain a Tudor domain are corroborated by more recent database search techniques such as PSI-BLAST (unpublished).


Pssm-ID: 197660  Cd Length: 57  Bit Score: 43.80  E-value: 6.53e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45550712    521 YKPVVREYVLARFE-GSWYRGKVEQIivvpRQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:smart00333   1 PTFKVGDKVAARWEdGEWYRARIVKV----DGEQLYEVFFIDYGNEEVVPPSDLRQLPEEL 57
 
Name Accession Description Interval E-value
TUDOR pfam00567
Tudor domain;
136-250 1.41e-15

Tudor domain;


Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 73.16  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45550712   136 SGAMVYITDFISSNRCYIRDasESAERAFDEVCKKVNTIATLLPR---IKNPPPNRLCLVHFNGMYVRAKM-CKKLREVS 211
Cdd:pfam00567   1 STIDVVVSHIESPSTFYIQP--KSDSKKLEKLTEELQEYYASKPPeslPPAVGDGCVAAFSEDGKWYRAKItESLDDGLV 78

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 45550712   212 HLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKN 250
Cdd:pfam00567  79 EVLFIDYGNTETVPLSDLRPLPPELESLPPQAIKCQLAG 117
zf-MYND pfam01753
MYND finger;
20-55 2.85e-09

MYND finger;


Pssm-ID: 460312  Cd Length: 39  Bit Score: 52.81  E-value: 2.85e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 45550712    20 CVHCANAAERV--CQRCGD-FYCSKHCQRQDWLRHRYIC 55
Cdd:pfam01753   1 CAVCGKEALKLlrCSRCKSvYYCSKECQKADWPYHKKEC 39
TUDOR pfam00567
Tudor domain;
519-580 1.04e-06

Tudor domain;


Pssm-ID: 425754 [Multi-domain]  Cd Length: 117  Bit Score: 47.73  E-value: 1.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45550712   519 EPYKPVVREYVLARF--EGSWYRGKveqiIVVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:pfam00567  44 ESLPPAVGDGCVAAFseDGKWYRAK----ITESLDDGLVEVLFIDYGNTETVPLSDLRPLPPEL 103
Tudor_TDRD11 cd20433
Tudor domain found in Tudor domain-containing protein 11 (TDRD11) and similar proteins; TDRD11, ...
 520-581 1.85e-06

Tudor domain found in Tudor domain-containing protein 11 (TDRD11) and similar proteins; TDRD11, also called Staphylococcal nuclease domain-containing protein 1 (SND1), 100 kDa coactivator, EBNA2 coactivator p100, or p100 co-activator, is a multifunctional protein that is reportedly associated with different types of RNA molecules, including mRNA, miRNA, pre-miRNA, and dsRNA. It has been implicated in a number of biological processes in eukaryotic cells, including the cell cycle, DNA damage repair, proliferation, and apoptosis. TDRD11 is overexpressed in multiple cancers and functions as an oncogene. It contains multiple Staphylococcal nuclease (SN) domains and a C-terminal Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410504 [Multi-domain]  Cd Length: 84  Bit Score: 46.14  E-value: 1.85e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45550712 520 PYKPVVREYVLARFE--GSWYRGKVEQIivvpRQQTKYRVMYLDYTNVEDITEMDIRRYPLDFT 581
Cdd:cd20433  25 SYTPRKGDLCAAKFVedGEWYRAKVEKV----EGDKKVHVLYIDYGNREVLPSTRLAALPPAFS 84
TUDOR smart00333
Tudor domain; Domain of unknown function present in several RNA-binding proteins. 10 copies in ...
 521-580 6.53e-06

Tudor domain; Domain of unknown function present in several RNA-binding proteins. 10 copies in the Drosophila Tudor protein. Initial proposal that the survival motor neuron gene product contain a Tudor domain are corroborated by more recent database search techniques such as PSI-BLAST (unpublished).


Pssm-ID: 197660  Cd Length: 57  Bit Score: 43.80  E-value: 6.53e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45550712    521 YKPVVREYVLARFE-GSWYRGKVEQIivvpRQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:smart00333   1 PTFKVGDKVAARWEdGEWYRARIVKV----DGEQLYEVFFIDYGNEEVVPPSDLRQLPEEL 57
Tudor_vreteno-like_rpt2 cd20445
second Tudor domain found in Drosophila melanogaster protein vreteno and similar proteins; ...
 527-583 7.13e-06

second Tudor domain found in Drosophila melanogaster protein vreteno and similar proteins; Vreteno is a gonad-specific protein essential for germline development to repress transposable elements and preventing their mobilization, which is essential for germline integrity. It acts via the piRNA metabolic process in both germline and somatic gonadal tissues by mediating the repression of transposable elements during meiosis. Vreteno contains two Tudor domains. The model corresponds to the second one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410516  Cd Length: 56  Bit Score: 43.57  E-value: 7.13e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 45550712 527 EYVLARFEGSWYRGkveqIIVVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDFTAP 583
Cdd:cd20445   3 ELCIAKYMDKWYRA----VCLESVGDGRPTVLFCDYGNILMARLTDIRPFPPTFATE 55
Tudor_TDRD1_rpt1 cd20408
first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins; ...
 519-597 1.14e-05

first Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins; TDRD1, also called cancer/testis antigen 41.1 (CT41.1), plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins, and governs the methylation and subsequent repression of transposons. TDRD1 contains four Tudor domains. This model corresponds to the first one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410479  Cd Length: 130  Bit Score: 45.05  E-value: 1.14e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45550712 519 EPYKPVVREYVLARF--EGSWYRGKVEQiivVPRQQTKYRVMYLDYTNVEDITEMDIRRYPLDFTA--PCATNLCVIDEF 594
Cdd:cd20408  43 KEYIPEVGEVCVAKYseDQNWYRALVQT---VDVQQKKAGVFYIDYGNEETVPLNRIQPLKKDIELfpPCAIKCCLANVK 119


                ...
gi 45550712 595 PHN 597
Cdd:cd20408 120 PPS 122
Tudor_dTUD-like cd20379
Tudor domain found in Drosophila melanogaster maternal protein Tudor (dTUD) and similar ...
 527-575 5.01e-05

Tudor domain found in Drosophila melanogaster maternal protein Tudor (dTUD) and similar proteins; dTUD is required during oogenesis for the formation of primordial germ cells and for normal abdominal segmentation. It contains 11 Tudor domains. The family also includes mitochondrial A-kinase anchor protein 1 (AKAP1) and Tudor domain-containing proteins (TDRDs). AKAP1, also called A-kinase anchor protein 149 kDa (AKAP 149), or dual specificity A-kinase-anchoring protein 1 (D-AKAP-1), or protein kinase A-anchoring protein 1 (PRKA1), or Spermatid A-kinase anchor protein 84 (S-AKAP84), is found in mitochondria and in the endoplasmic reticulum-nuclear envelope where it anchors protein kinases, phosphatases, and a phosphodiesterase. It regulates multiple cellular processes governing mitochondrial homeostasis and cell viability. AKAP1 binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. TDRDs have diverse biological functions and may contain one or more copies of the Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410450  Cd Length: 50  Bit Score: 40.96  E-value: 5.01e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 45550712 527 EYVLARFE--GSWYRGKVEQIIvvprQQTKYRVMYLDYTNVEDITEMDIRR 575
Cdd:cd20379   3 DLCAAKYEedGKWYRARVLEVL----SNDKVEVFFVDYGNTETVPLSDLRP 49
Tudor_SF cd04508
Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally ...
 527-575 1.25e-04

Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally identified in the Tudor protein of Drosophila, that adopts a beta-barrel-like core structure containing four short beta-strands followed by an alpha-helical region. It binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions. Tudor domain-containing proteins may mediate protein-protein interactions required for various DNA-templated biological processes, such as RNA metabolism, as well as histone modification and the DNA damage response. Members of this superfamily contain one or more copies of the Tudor domain.


Pssm-ID: 410449 [Multi-domain]  Cd Length: 47  Bit Score: 39.88  E-value: 1.25e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 45550712 527 EYVLARFE--GSWYRGKVEQIivvpRQQTKYRVMYlDYTNVEDITEMDIRR 575
Cdd:cd04508   2 DRVEAKWSddGQWYPATVVAV----NDDGKYTVLF-DDGNEEEVSEDDIRP 47
Tudor_TDRD4_rpt2 cd20415
second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins; ...
 519-591 1.86e-04

second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins; TDRD4, also called RING finger protein 17 (RNF17), is a component of the mammalian germ cell nuage and is essential for spermiogenesis. It seems to be involved in the regulation of transcriptional activity of MYC. In vitro, TDRD4 inhibits the DNA-binding activity of Mad-MAX heterodimers. It can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. TDRD4 also acts as a potential cancer/testis antigen in liver cancer. TDRD4 contains a RING finger and five Tudor domains. This model corresponds to the second one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410486  Cd Length: 96  Bit Score: 40.88  E-value: 1.86e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45550712 519 EPYKPVVREYVLARFE-GSWYRGkveQIIVVPRQQtKYRVMYLDYTNVEDITEMDIRRYPLDF-TAPCATNLCVI 591
Cdd:cd20415  21 EILCPVQGQACVALFEdGAWYRA---RIIGLPGHR-EVEVKYVDFGNTATVTIKHVRKIKDDFlSLPEKARECRL 91
Tudor_TDRD1_rpt3 cd20410
third Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins; ...
 521-580 1.89e-04

third Tudor domain found in Tudor domain-containing protein 1 (TDRD1) and similar proteins; TDRD1, also called cancer/testis antigen 41.1 (CT41.1), plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins, and governs the methylation and subsequent repression of transposons. TDRD1 contains four Tudor domains. This model corresponds to the third one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410481 [Multi-domain]  Cd Length: 59  Bit Score: 39.63  E-value: 1.89e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45550712 521 YKPVVREYVLARF--EGSWYRGKVEQIIvvprQQTKYRVMYLDYTNVEDITEMDIRRYPLDF 580
Cdd:cd20410   1 FKPIVGEPCCAFFsgDGNWYRAMVKEIL----PGGAVKVHFVDYGNVEEVTLDKLRKITSTF 58
Tudor_vreteno-like_rpt1 cd20444
first Tudor domain found in Drosophila melanogaster protein vreteno and similar proteins; ...
 523-569 3.59e-04

first Tudor domain found in Drosophila melanogaster protein vreteno and similar proteins; Vreteno is a gonad-specific protein essential for germline development to repress transposable elements and preventing their mobilization, which is essential for germline integrity. It acts via the piRNA metabolic process in both germline and somatic gonadal tissues by mediating the repression of transposable elements during meiosis. Vreteno contains two Tudor domains. The model corresponds to the first one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410515  Cd Length: 55  Bit Score: 38.82  E-value: 3.59e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*..
gi 45550712 523 PVVREYVLARFEGSWYRGKVEQiivVPRQQTKYRVMYLDYTNVEDIT 569
Cdd:cd20444   1 PTPGQMVIAKFDGNHYRAIVLR---VLNPDLKILVRFVDFGNVEVMK 44
Tudor_AtTudor1-like cd20443
Tudor domain found in Arabidopsis thaliana ribonuclease Tudor 1 (AtTudor1), ribonuclease Tudor ...
 527-589 8.76e-04

Tudor domain found in Arabidopsis thaliana ribonuclease Tudor 1 (AtTudor1), ribonuclease Tudor 2 (AtTudor2), and similar proteins; The family includes AtTudor1 (also called Tudor-SN protein 1) and AtTudor2 (also called Tudor-SN protein 2 or 100 kDa coactivator-like protein). They are cytoprotective ribonucleases (RNases) required for resistance to abiotic stresses, acting as positive regulators of mRNA decapping during stress. Members of this family contain one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410514 [Multi-domain]  Cd Length: 117  Bit Score: 39.37  E-value: 8.76e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 45550712 527 EYVLARF--EGSWYRGKVeqiIVVPRQQT-----KYRVMYLDYTNVEDITEMDIRryPLD---FTAPCATNLC 589
Cdd:cd20443  42 ELVLAQFsaDNSWNRAMV---VNAPRQGTqspkdEYEVFYIDYGNQETVPLSALR--PLDpsvSSAPGLAQLC 109
Tudor_TDRD8 cd20430
Tudor domain found in Tudor domain-containing protein 8 (TDRD8) and similar proteins; TDRD8, ...
 536-581 7.82e-03

Tudor domain found in Tudor domain-containing protein 8 (TDRD8) and similar proteins; TDRD8, also called serine/threonine-protein kinase (EC 2.7.11.1) 31 (STK31), serine/threonine-protein kinase NYD-SPK, or Sugen kinase 396 (SgK396), is a germ cell-specific factor expressed in embryonic gonocytes of both sexes, and in postnatal spermatocytes and round spermatids in males. It acts as a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. TDRD8 contains a Tudor domain and a serine/threonine kinase domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.


Pssm-ID: 410501 [Multi-domain]  Cd Length: 75  Bit Score: 35.73  E-value: 7.82e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 45550712 536 SWYRGKVEQIIvvprQQTKYRVMYLDYTNVEDITEMDIRRYPLDFT 581
Cdd:cd20430  34 CWYRCKVKSIL----SDEKCTVQYIDYGNTETVSRSSIVELPPDLQ 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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