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Conserved domains on  [gi|24664419|ref|NP_648738|]
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uncharacterized protein Dmel_CG13461 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CobT2 super family cl34772
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 24-125 2.93e-06

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


The actual alignment was detected with superfamily member COG4547:

Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 45.17  E-value: 2.93e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419  24 EDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDsgnvdnqdDENSEDNQEESDNESSGDDEEDNNGSDDNTESDN 103
Cdd:COG4547 208 AEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDE--------GAEAEDAEASGDDAEEGESEAAEAESDEMAEEAE 279

                        90       100
                ....*....|....*....|....*
gi 24664419 104 NNDSE---GDQEQDAPPNNQIRPFG 125
Cdd:COG4547 280 GEDSEepgEPWRPNAPPPDDPADPD 304
 
Name Accession Description Interval E-value
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 24-125 2.93e-06

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 45.17  E-value: 2.93e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419  24 EDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDsgnvdnqdDENSEDNQEESDNESSGDDEEDNNGSDDNTESDN 103
Cdd:COG4547 208 AEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDE--------GAEAEDAEASGDDAEEGESEAAEAESDEMAEEAE 279

                        90       100
                ....*....|....*....|....*
gi 24664419 104 NNDSE---GDQEQDAPPNNQIRPFG 125
Cdd:COG4547 280 GEDSEepgEPWRPNAPPPDDPADPD 304
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 69-114 1.70e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 43.00  E-value: 1.70e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24664419    69 DDENSEDNQEESDNESSGDDEEDNNGSDDNTESDNNNDSEGDQEQD 114
Cdd:pfam04931 632 QQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDD 677
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 19-120 2.18e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 39.89  E-value: 2.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419   19 AARPAEDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDN 98
Cdd:PRK12678 150 EQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGR 229

                         90       100
                 ....*....|....*....|..
gi 24664419   99 TESDNNNDSEGDQEQDAPPNNQ 120
Cdd:PRK12678 230 RRRRDRRDARGDDNREDRGDRD 251
 
Name Accession Description Interval E-value
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 24-125 2.93e-06

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 45.17  E-value: 2.93e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419  24 EDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDsgnvdnqdDENSEDNQEESDNESSGDDEEDNNGSDDNTESDN 103
Cdd:COG4547 208 AEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDE--------GAEAEDAEASGDDAEEGESEAAEAESDEMAEEAE 279

                        90       100
                ....*....|....*....|....*
gi 24664419 104 NNDSE---GDQEQDAPPNNQIRPFG 125
Cdd:COG4547 280 GEDSEepgEPWRPNAPPPDDPADPD 304
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 69-114 1.70e-05

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 43.00  E-value: 1.70e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24664419    69 DDENSEDNQEESDNESSGDDEEDNNGSDDNTESDNNNDSEGDQEQD 114
Cdd:pfam04931 632 QQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDD 677
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 19-120 2.18e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 39.89  E-value: 2.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419   19 AARPAEDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDN 98
Cdd:PRK12678 150 EQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGR 229

                         90       100
                 ....*....|....*....|..
gi 24664419   99 TESDNNNDSEGDQEQDAPPNNQ 120
Cdd:PRK12678 230 RRRRDRRDARGDDNREDRGDRD 251
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 64-122 5.86e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 38.37  E-value: 5.86e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24664419    64 NVDNQDD--ENSEDNQEESDNESSGDDEEDNNGSDDNTESDNNNDSEGDQEQDAPPNNQIR 122
Cdd:pfam04931 628 NPEGQQElfEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDELR 688
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 59-112 1.23e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 37.60  E-value: 1.23e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 24664419    59 SQDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDNTESDNNNDSEGDQE 112
Cdd:pfam04931 631 GQQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEI 684
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 23-112 2.76e-03

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 36.42  E-value: 2.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664419   23 AEDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDNTESD 102
Cdd:PRK12678 197 GRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRG 276

                         90
                 ....*....|
gi 24664419  103 NNNDSEGDQE 112
Cdd:PRK12678 277 GDGGNEREPE 286
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 60-103 3.66e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 36.06  E-value: 3.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 24664419    60 QDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDNTESDN 103
Cdd:pfam04931 643 EEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDE 686
Nop14 pfam04147
Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the ...
 24-102 9.46e-03

Nop14-like family; Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.


Pssm-ID: 461196  Cd Length: 835  Bit Score: 34.91  E-value: 9.46e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24664419    24 EDEESSIQDNTNEDSSSNDGEGNSDAAEEEPAVEESQDSGNVDNQDDENSEDNQEESDNESSGDDEEDNNGSDDNTESD 102
Cdd:pfam04147 334 EDEDDFIIDDDLVESESDLELDEEEEDEEEEDDEDEDEEEEEDDDDLSDLESEEDEEDDEFEEEKKKKKKKDEEGAKEE 412
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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