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Conserved domains on  [gi|20302127|ref|NP_620274|]
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protein unc-50 homolog [Rattus norvegicus]

Protein Classification

unc-50 family protein( domain architecture ID 10525182)

unc-50 family protein similar to Caenorhabditis elegans protein unc-50 that is required for cell surface expression of acetylcholine receptors in body-wall muscles

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UNC-50 pfam05216
UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ...
34-255 4.10e-108

UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ARF exchange factors.


:

Pssm-ID: 461592  Cd Length: 223  Bit Score: 311.36  E-value: 4.10e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127    34 YLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKL 113
Cdd:pfam05216   1 YLRRLFKFRQMDFETALWQMFYLCIAPRKVYRNFYYRKQTKNQWARDDPAFLVLLSGFLCISAIAWSLAYGLSFLGFLKL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127   114 LLWVVFIDCVGVGLLISTLMWFISNKYLVKR--QSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINhVILTDTFIGY 191
Cdd:pfam05216  81 ILYMVFVDFLLVGLIIATLFWFLANRFLRKSspSAVEQDVEWGYAFDVHCNAFFPILVLLYVLQLFLLP-LLLRHNFISL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20302127   192 LVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVVLLYPFAPLIVLYGLSLALGWNFTHTLCSFYK 255
Cdd:pfam05216 160 LLGNTLYLVALGYYFYITFLGYNALPFLKNTELLLYPIPLLAVLYLVTSLFGFNVSKHVLSFYF 223
 
Name Accession Description Interval E-value
UNC-50 pfam05216
UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ...
34-255 4.10e-108

UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ARF exchange factors.


Pssm-ID: 461592  Cd Length: 223  Bit Score: 311.36  E-value: 4.10e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127    34 YLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKL 113
Cdd:pfam05216   1 YLRRLFKFRQMDFETALWQMFYLCIAPRKVYRNFYYRKQTKNQWARDDPAFLVLLSGFLCISAIAWSLAYGLSFLGFLKL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127   114 LLWVVFIDCVGVGLLISTLMWFISNKYLVKR--QSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINhVILTDTFIGY 191
Cdd:pfam05216  81 ILYMVFVDFLLVGLIIATLFWFLANRFLRKSspSAVEQDVEWGYAFDVHCNAFFPILVLLYVLQLFLLP-LLLRHNFISL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20302127   192 LVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVVLLYPFAPLIVLYGLSLALGWNFTHTLCSFYK 255
Cdd:pfam05216 160 LLGNTLYLVALGYYFYITFLGYNALPFLKNTELLLYPIPLLAVLYLVTSLFGFNVSKHVLSFYF 223
 
Name Accession Description Interval E-value
UNC-50 pfam05216
UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ...
34-255 4.10e-108

UNC-50 family; Gmh1p from S. cerevisiae is located in the Golgi membrane and interacts with ARF exchange factors.


Pssm-ID: 461592  Cd Length: 223  Bit Score: 311.36  E-value: 4.10e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127    34 YLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKL 113
Cdd:pfam05216   1 YLRRLFKFRQMDFETALWQMFYLCIAPRKVYRNFYYRKQTKNQWARDDPAFLVLLSGFLCISAIAWSLAYGLSFLGFLKL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20302127   114 LLWVVFIDCVGVGLLISTLMWFISNKYLVKR--QSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINhVILTDTFIGY 191
Cdd:pfam05216  81 ILYMVFVDFLLVGLIIATLFWFLANRFLRKSspSAVEQDVEWGYAFDVHCNAFFPILVLLYVLQLFLLP-LLLRHNFISL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 20302127   192 LVGNTLWLIAVGYYIYVTFLGYSALPFLKNTVVLLYPFAPLIVLYGLSLALGWNFTHTLCSFYK 255
Cdd:pfam05216 160 LLGNTLYLVALGYYFYITFLGYNALPFLKNTELLLYPIPLLAVLYLVTSLFGFNVSKHVLSFYF 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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