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Conserved domains on  [gi|22024255|ref|NP_611787|]
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Golgin-245 [Drosophila melanogaster]

Protein Classification

GRIP and coiled-coil domain-containing protein( domain architecture ID 13380436)

GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 583-1247 2.81e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 2.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  583 INELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLE-QSLNA-----LKTESEHSLQDLRLHNDQLLEI---VQRH 653
Cdd:COG1196  167 ISKYKERKEEAERKLEATEENLERLEDILGELERQLEPLErQAEKAeryreLKEELKELEAELLLLKLRELEAeleELEA 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  654 QQNDWEAQLARAREELAAIQSQRE---LHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDqhansE 730
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-----L 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  731 SETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESE 810
Cdd:COG1196  322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  811 KEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCL 890
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  891 LEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHskLQNAQELMDHDHRTLQDKCDAYEKDklltkhtldCLQSASEELHR 970
Cdd:COG1196  482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAAL--LLAGLRGLAGAVAVLIGVEAAYEAA---------LEAALAAALQN 550

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  971 VKANLDRELKEQDQQLselrerqrEQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATN 1050
Cdd:COG1196  551 IVVEDDEVAAAAIEYL--------KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1051 SSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEA 1130
Cdd:COG1196  623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1131 SEKLAkfdEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKEtqsATATAEVSELKKAI 1210
Cdd:COG1196  703 EEEER---ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL---EELERELERLEREI 776

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....
gi 22024255 1211 EE-QAV------ELTRQKEHASFVTEQSDavqkDLLQAQQQLHD 1247
Cdd:COG1196  777 EAlGPVnllaieEYEELEERYDFLSEQRE----DLEEARETLEE 816
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 286-856 1.26e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.26e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  286 LQRLLKERDEQLKS------VTEKYEAVRKQEEE---NVLLLA-----QTKQAIHTELELKDTEVRKLQEKLKQLESQRE 351
Cdd:COG1196  191 LEDILGELERQLEPlerqaeKAERYRELKEELKEleaELLLLKlreleAELEELEAELEELEAELEELEAELAELEAELE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  352 SHNNEVKE---QFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR---VENEQKVKDLQKQNEDRN 425
Cdd:COG1196  271 ELRLELEElelELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEeelEELEEELEELEEELEEAE 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  426 TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLD---KLRENKKSSDSQT 502
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErleRLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  503 NEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQ-- 580
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgv 510

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  581 --QKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEhsLQDLRLHNDQLLEIVQRHQQNDW 658
Cdd:COG1196  511 kaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY--LKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  659 EAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALK 738
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  739 GQLEALSQDLATSQASLLAKEKELKASgnklnkiKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARV 818
Cdd:COG1196  669 ELLAALLEAEAELEELAERLAEEELEL-------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 22024255  819 TGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESL 856
Cdd:COG1196  742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1433-1477 5.28e-10

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 56.07  E-value: 5.28e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 22024255    1433 NTEFEYLRNIMFQYLTGNTN-NETLVKVISAVLKFSPQQAQVALEK 1477
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESeRETLLPVISTVLQLSPEEMQKLLEV 46
MIT_CorA-like super family cl00459
metal ion transporter CorA-like divalent cation transporter superfamily; This superfamily of ...
 1244-1333 6.78e-03

metal ion transporter CorA-like divalent cation transporter superfamily; This superfamily of essential membrane proteins is involved in transporting divalent cations (uptake or efflux) across membranes. They are found in most bacteria and archaea, and in some eukaryotes. It is a functionally diverse group which includes the Mg2+ transporters of Escherichia coli and Salmonella typhimurium CorAs (which can also transport Co2+, and Ni2+ ), the CorA Co2+ transporter from the hyperthermophilic Thermotoga maritima, and the Zn2+ transporter Salmonella typhimurium ZntB, which mediates the efflux of Zn2+ (and Cd2+). It includes five Saccharomyces cerevisiae members: i) two plasma membrane proteins, the Mg2+ transporter Alr1p/Swc3p and the putative Mg2+ transporter, Alr2p, ii) two mitochondrial inner membrane Mg2+ transporters: Mfm1p/Lpe10p, and Mrs2p, and iii) and the vacuole membrane protein Mnr2p, a putative Mg2+ transporter. It also includes a family of Arabidopsis thaliana members (AtMGTs), some of which are localized to distinct tissues, and not all of which can transport Mg2+. Thermotoga maritima CorA and Vibrio parahaemolyticus and Salmonella typhimurium ZntB form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, Mrs2p, and Alr1p. Natural variants such as GVN and GIN, as in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.


The actual alignment was detected with superfamily member cd12833:

Pssm-ID: 469776 [Multi-domain]  Cd Length: 290  Bit Score: 40.17  E-value: 6.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1244 QLHDK--QIELAMSRDEQALLQAEADGLRQEVICLKEHLSP-----------------STDSDSLRSLNERLQRELEDLk 1304
Cdd:cd12833  126 ELEDRldELEERVLEEEDEELRGELAELRRQAIALRRYLAPqrdalerlaredlpwlsDDDRLRLREAADRLTRYIEDL- 204

                         90       100
                 ....*....|....*....|....*....
gi 22024255 1305 hKSAGAESNMQQeiEELqanNQQMAERIN 1333
Cdd:cd12833  205 -DAIRERAAVLQ--EEL---TNRRAEQMN 227
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 583-1247 2.81e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 2.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  583 INELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLE-QSLNA-----LKTESEHSLQDLRLHNDQLLEI---VQRH 653
Cdd:COG1196  167 ISKYKERKEEAERKLEATEENLERLEDILGELERQLEPLErQAEKAeryreLKEELKELEAELLLLKLRELEAeleELEA 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  654 QQNDWEAQLARAREELAAIQSQRE---LHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDqhansE 730
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-----L 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  731 SETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESE 810
Cdd:COG1196  322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  811 KEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCL 890
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  891 LEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHskLQNAQELMDHDHRTLQDKCDAYEKDklltkhtldCLQSASEELHR 970
Cdd:COG1196  482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAAL--LLAGLRGLAGAVAVLIGVEAAYEAA---------LEAALAAALQN 550

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  971 VKANLDRELKEQDQQLselrerqrEQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATN 1050
Cdd:COG1196  551 IVVEDDEVAAAAIEYL--------KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1051 SSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEA 1130
Cdd:COG1196  623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1131 SEKLAkfdEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKEtqsATATAEVSELKKAI 1210
Cdd:COG1196  703 EEEER---ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL---EELERELERLEREI 776

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....
gi 22024255 1211 EE-QAV------ELTRQKEHASFVTEQSDavqkDLLQAQQQLHD 1247
Cdd:COG1196  777 EAlGPVnllaieEYEELEERYDFLSEQRE----DLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 286-1034 3.73e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 3.73e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    286 LQRLLKERDEQLKS------VTEKYEAVRKQEEE-NVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQ---RESHNN 355
Cdd:TIGR02168  191 LEDILNELERQLKSlerqaeKAERYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAElqeLEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    356 EVKEQFKKLQATKQEVDAKLMATEHLLNTL---KESYAIKEQQVVTLEAQLEAIRVENEQK-------VKDLQKQNEDRN 425
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLeqqKQILRERLANLERQLEELEAQLEELESKldelaeeLAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    426 TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLgklkQENENYLDKLRENKKSSDSQTNEA 505
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI----ERLEARLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    506 QDQQKKlqAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINE 585
Cdd:TIGR02168  427 LKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGF 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    586 LRAAKDEAEAKLLSTEHsLNALQAALSAKEEQAASLE----QSLNALKTESEHSLQD-----------------LRLHND 644
Cdd:TIGR02168  505 SEGVKALLKNQSGLSGI-LGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKaiaflkqnelgrvtflpLDSIKG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    645 QLLEIVQRHQQ------------------------NDWEAQLARAREELAAIQSQRELHALELEKSLEME---RESVAAL 697
Cdd:TIGR02168  584 TEIQGNDREILkniegflgvakdlvkfdpklrkalSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDlvrPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    698 NSEKASQEEQHR-LKLEQLQREIQILQDQHANSESEtVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQH 776
Cdd:TIGR02168  664 GSAKTNSSILERrREIEELEEKIEELEEKIAELEKA-LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    777 EQHQAKSSDQSARLEALQSELAdrlshsrQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESL 856
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIE-------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    857 QQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHD 936
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    937 HRTLQDKcdayekdklltkhtldcLQSASEELHRvkanLDRELKEQDQQLSELRERQREQEQQLKDQAERCA-------- 1008
Cdd:TIGR02168  896 LEELSEE-----------------LRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeysltle 954

                          810       820
                   ....*....|....*....|....*....
gi 22024255   1009 ---KLKAQNSESETQLQATISNLREQLDA 1034
Cdd:TIGR02168  955 eaeALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 286-856 1.26e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.26e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  286 LQRLLKERDEQLKS------VTEKYEAVRKQEEE---NVLLLA-----QTKQAIHTELELKDTEVRKLQEKLKQLESQRE 351
Cdd:COG1196  191 LEDILGELERQLEPlerqaeKAERYRELKEELKEleaELLLLKlreleAELEELEAELEELEAELEELEAELAELEAELE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  352 SHNNEVKE---QFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR---VENEQKVKDLQKQNEDRN 425
Cdd:COG1196  271 ELRLELEElelELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEeelEELEEELEELEEELEEAE 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  426 TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLD---KLRENKKSSDSQT 502
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErleRLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  503 NEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQ-- 580
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgv 510

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  581 --QKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEhsLQDLRLHNDQLLEIVQRHQQNDW 658
Cdd:COG1196  511 kaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY--LKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  659 EAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALK 738
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  739 GQLEALSQDLATSQASLLAKEKELKASgnklnkiKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARV 818
Cdd:COG1196  669 ELLAALLEAEAELEELAERLAEEELEL-------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 22024255  819 TGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESL 856
Cdd:COG1196  742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 303-948 6.15e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 6.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   303 KYEAVRKQEEenvllLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKlmatehll 382
Cdd:PTZ00121 1183 KAEEVRKAEE-----LRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER-------- 1249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   383 nTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQllSKDQLLESLRSE 462
Cdd:PTZ00121 1250 -NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA--KKADEAKKKAEE 1326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   463 QAAKEQQLKHLKEQLGK----LKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEEllhslrnDYK 538
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeaAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------KKK 1399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   539 AQEEKVALLEDKLKTLSKENDVNVEKlhhinEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQA 618
Cdd:PTZ00121 1400 AEEDKKKADELKKAAAAKKKADEAKK-----KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   619 ASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALN 698
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   699 SEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNK---IKKQ 775
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKaeeEKKK 1634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   776 HEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVtgilEEIGTMQAQMQQVQDSHSELEREKRKLEsRIES 855
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKK 1709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   856 LQQEQVDSSAQ----DERTSAKLEEIQ---SENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQN 928
Cdd:PTZ00121 1710 KEAEEKKKAEElkkaEEENKIKAEEAKkeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789

                         650       660
                  ....*....|....*....|
gi 22024255   929 AQELMDHDhRTLQDKCDAYE 948
Cdd:PTZ00121 1790 EKRRMEVD-KKIKDIFDNFA 1808
PTZ00121 PTZ00121
MAEBL; Provisional
 146-869 7.40e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 7.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   146 DQLYDAYKKSLDRYHKYRCRYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAH-LEEALRVEMD 224
Cdd:PTZ00121 1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARkAEDARKAEEA 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   225 ---DMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESigKSPLSTNGSSGVSDLQRLLKERDEQLKSVT 301
Cdd:PTZ00121 1170 rkaEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDAEEAKKAEE 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   302 EK-YEAVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMATEh 380
Cdd:PTZ00121 1248 ERnNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE- 1326

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   381 llnTLKESYAIKEQQVVTLEAQlEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQllSKDQLLESLR 460
Cdd:PTZ00121 1327 ---AKKKADAAKKKAEEAKKAA-EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK--KKADEAKKKA 1400

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   461 SEQAAKEQQLKHLKEQLGKLKQenenyLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKllATEELLHSLRNDYKAQ 540
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKADE-----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK--KAEEAKKKAEEAKKAD 1473

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   541 EEKVALLE----DKLKTLSKENDVNVEKLHHINEQR----EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALS 612
Cdd:PTZ00121 1474 EAKKKAEEakkaDEAKKKAEEAKKKADEAKKAAEAKkkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   613 AKEEQAASLEQSLNALKTESEHSLQDLRlhndqlleivqrhqqndwEAQLARAREELAAIQSQRELHALELEKSLEMERE 692
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALR------------------KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   693 SVAALNSEKASQEEQHRLKLEQLQR--EIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLN 770
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   771 KI---KKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVtgilEEIGTMQAQMQQVQDSHSELEREKR 847
Cdd:PTZ00121 1696 KEaeeAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA----EEAKKDEEEKKKIAHLKKEEEKKAE 1771

                         730       740
                  ....*....|....*....|..
gi 22024255   848 KLESRIESLQQEQVDSSAQDER 869
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRR 1793
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 201-921 3.04e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.69  E-value: 3.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    201 LREQCTLEQQAKAHLEEA---LRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIdleesigKSPLST 277
Cdd:pfam15921   94 LNESNELHEKQKFYLRQSvidLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCL-------KEDMLE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    278 NGSSGVSDLQRLLKERD---EQLKSVTEKYE-----AVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQ 349
Cdd:pfam15921  167 DSNTQIEQLRKMMLSHEgvlQEIRSILVDFEeasgkKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    350 RESHNNEVKEQFKKLQATKQEVDAKLMATEHL-LNTLKESYAIKEQQVVTLEAQLEAI----RVENEQKVKDLQKQNEDR 424
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLISEHEVeITGLTEKASSARSQANSIQSQLEIIqeqaRNQNSMYMRQLSDLESTV 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    425 NTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKL-----KQENENYLDKlRENKKSSD 499
Cdd:pfam15921  327 SQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhKREKELSLEK-EQNKRLWD 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    500 SQTNEAQDQQKkLQAAKDEAESKLLATEELLHSLRNDYKAQ-EEKVALLEDKLKTLskendvnvEKLHHINEQREAQSTD 578
Cdd:pfam15921  406 RDTGNSITIDH-LRRELDDRNMEVQRLEALLKAMKSECQGQmERQMAAIQGKNESL--------EKVSSLTAQLESTKEM 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    579 SQQKINELRAAKDEAEakllSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIvqRHQQNDW 658
Cdd:pfam15921  477 LRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL--RNVQTEC 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    659 EAQLARAREELAAIQSQRElHALELEKSLEMERESVAALNSEKASQEEQ---HRLKLEQLQ-------REIQILQDQHAN 728
Cdd:pfam15921  551 EALKLQMAEKDKVIEILRQ-QIENMTQLVGQHGRTAGAMQVEKAQLEKEindRRLELQEFKilkdkkdAKIRELEARVSD 629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    729 SESETVAALKGQLEALS--QDLATSQASLLakeKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLShSRQ 806
Cdd:pfam15921  630 LELEKVKLVNAGSERLRavKDIKQERDQLL---NEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK-SAQ 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    807 VESEKEE-------------------LQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQD 867
Cdd:pfam15921  706 SELEQTRntlksmegsdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255    868 ERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGK-----IQAKLQQVLD 921
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRqeqesVRLKLQHTLD 844
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 328-1346 5.68e-12

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 70.97  E-value: 5.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    328 ELELKDTEVRKLQEKLKQLESqreshnnevkeQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQqvvtLEAQLEAIR 407
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAES-----------ELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARK 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    408 VENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLkqeneny 487
Cdd:pfam01576   71 QELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL------- 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    488 ldklrenkkssDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENdvnvEKLHH 567
Cdd:pfam01576  144 -----------EDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGR----QELEK 208

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    568 INEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALsaKEEQAAsleqslnalKTESEHSLQDLRLHNDQLL 647
Cdd:pfam01576  209 AKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARL--EEETAQ---------KNNALKKIRELEAQISELQ 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    648 EIVQRHQQndweaqlARAREELAAIQSQRELHALELEksLEMERESVAALNSEKASQEEQhrlkLEQLQREIQILQDQHA 727
Cdd:pfam01576  278 EDLESERA-------ARNKAEKQRRDLGEELEALKTE--LEDTLDTTAAQQELRSKREQE----VTELKKALEEETRSHE 344

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    728 NSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQV 807
Cdd:pfam01576  345 AQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSES 424

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    808 ESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAER 887
Cdd:pfam01576  425 ERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQ 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    888 NCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVL-------DEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDC 960
Cdd:pfam01576  505 LEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAgtlealeEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDD 584

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    961 LQSASEELHRVKANLDRELKEQDQQLSeLRERQREQEQQLKDQAERCAKlkaqnsESETQLQATISNLREQLDAykqteq 1040
Cdd:pfam01576  585 LLVDLDHQRQLVSNLEKKQKKFDQMLA-EEKAISARYAEERDRAEAEAR------EKETRALSLARALEEALEA------ 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1041 giQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATR 1120
Cdd:pfam01576  652 --KEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQF 729

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1121 DRQLQEKIEASEKLAKfdeilieneYLNKHTKQLEAELAESAELKEKL----KSLQCELYVLQEKAEQHAVQMAEKETQS 1196
Cdd:pfam01576  730 ERDLQARDEQGEEKRR---------QLVKQVRELEAELEDERKQRAQAvaakKKLELDLKELEAQIDAANKGREEAVKQL 800

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1197 ATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQqlhdkqiELAMSRDEQALLQAEADGLRQEVIcl 1276
Cdd:pfam01576  801 KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQE-------DLAASERARRQAQQERDELADEIA-- 871

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1277 kehlSPSTDSDSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQ 1346
Cdd:pfam01576  872 ----SGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSE 937
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1433-1477 5.28e-10

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 56.07  E-value: 5.28e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 22024255    1433 NTEFEYLRNIMFQYLTGNTN-NETLVKVISAVLKFSPQQAQVALEK 1477
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESeRETLLPVISTVLQLSPEEMQKLLEV 46
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 284-633 2.42e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 2.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    284 SDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHTelelKDTEVRKLQEKLKQLESQRESH-NNEVKEQFK 362
Cdd:TIGR04523  242 NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE----LEKQLNQLKSEISDLNNQKEQDwNKELKSELK 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    363 KLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQK---VKDLQKQNEDRNTQASDSSEQLKKLQ 439
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKqneIEKLKKENQSYKQEIKNLESQINDLE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    440 AAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDE- 518
Cdd:TIGR04523  398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSi 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    519 --AESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKEND---VNVEKLHHINEQREAQSTDSQQKINE-------- 585
Cdd:TIGR04523  478 nkIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISslkEKIEKLESEKKEKESKISDLEDELNKddfelkke 557

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 22024255    586 -LRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESE 633
Cdd:TIGR04523  558 nLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE 606
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 1433-1472 6.28e-07

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 47.35  E-value: 6.28e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 22024255   1433 NTEFEYLRNIMFQYLTGNTNNE--TLVKVISAVLKFSPQQAQ 1472
Cdd:pfam01465    1 GANLEYLKNVLLQFLESKESSErkQLLPVIATLLKFSPEEEQ 42
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 284-487 4.57e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   284 SDLQRLLKERDEQLKSVTekyeAVRKQ-EEENVLLLAQTKQ----AIHTELELKDTEVRKLQEKLKQLESQrESHNNEVK 358
Cdd:NF012221 1569 ADRQRLEQEKQQQLAAIS----GSQSQlESTDQNALETNGQaqrdAILEESRAVTKELTTLAQGLDALDSQ-ATYAGESG 1643

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   359 EQFKKLQA-------TKQEVDAKLMATEHLlNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQA--- 428
Cdd:NF012221 1644 DQWRNPFAgglldrvQEQLDDAKKISGKQL-ADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDAKADAekr 1722

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255   429 -SDSSEQLKKLQAAVQDAESqLLSKDQllesLRSEQAAKEQQLKHLKEQL-GKLKQENENY 487
Cdd:NF012221 1723 kDDALAKQNEAQQAESDANA-AANDAQ----SRGEQDASAAENKANQAQAdAKGAKQDESD 1778
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 268-633 3.55e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.00  E-value: 3.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   268 ESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAV--RKQEEENVLLLAQTkQAIHTELElkdTEVRKLQEKLKQ 345
Cdd:NF033838   38 EEVRGGNNPTVTSSGNESQKEHAKEVESHLEKILSEIQKSldKRKHTQNVALNKKL-SDIKTEYL---YELNVLKEKSEA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   346 -LESQRESHNNEVKEQFKK---------LQATKQEVDAKLMATE--------HLLNTLKE-SYAIKEQQVVTLEAQLEAI 406
Cdd:NF033838  114 eLTSKTKKELDAAFEQFKKdtlepgkkvAEATKKVEEAEKKAKDqkeedrrnYPTNTYKTlELEIAESDVEVKKAELELV 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   407 RVE-----NEQKVKDLQKQNEDRNTQASdsseQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLK 481
Cdd:NF033838  194 KEEakeprDEEKIKQAKAKVESKKAEAT----RLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGV 269

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   482 QENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESkllateellhslrndykaqEEKVALLEDKLKTLSKENDVN 561
Cdd:NF033838  270 LGEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEA-------------------EKKVEEAKKKAKDQKEEDRRN 330

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22024255   562 VEKLHHINEQREAQSTDSQQKINELRAAKDeaEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESE 633
Cdd:NF033838  331 YPTNTYKTLELEIAESDVKVKEAELELVKE--EAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEE 400
ZntB-like_1 cd12833
Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; A bacterial subgroup belonging to ...
 1244-1333 6.78e-03

Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; A bacterial subgroup belonging to the Escherichia coli CorA-Salmonella typhimurium ZntB_like family (EcCorA_ZntB-like) of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subgroup includes the Zn2+ transporter Salmonella typhimurium ZntB which mediates the efflux of Zn2+ (and Cd2+). Structures of the intracellular domain of Vibrio parahaemolyticus and Salmonella typhimurium ZntB form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, and Mrs2p. Natural variants such as GVN and GIN, which occur in proteins belonging to this subfamily, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.


Pssm-ID: 213367 [Multi-domain]  Cd Length: 290  Bit Score: 40.17  E-value: 6.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1244 QLHDK--QIELAMSRDEQALLQAEADGLRQEVICLKEHLSP-----------------STDSDSLRSLNERLQRELEDLk 1304
Cdd:cd12833  126 ELEDRldELEERVLEEEDEELRGELAELRRQAIALRRYLAPqrdalerlaredlpwlsDDDRLRLREAADRLTRYIEDL- 204

                         90       100
                 ....*....|....*....|....*....
gi 22024255 1305 hKSAGAESNMQQeiEELqanNQQMAERIN 1333
Cdd:cd12833  205 -DAIRERAAVLQ--EEL---TNRRAEQMN 227
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 583-1247 2.81e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 2.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  583 INELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLE-QSLNA-----LKTESEHSLQDLRLHNDQLLEI---VQRH 653
Cdd:COG1196  167 ISKYKERKEEAERKLEATEENLERLEDILGELERQLEPLErQAEKAeryreLKEELKELEAELLLLKLRELEAeleELEA 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  654 QQNDWEAQLARAREELAAIQSQRE---LHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDqhansE 730
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-----L 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  731 SETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESE 810
Cdd:COG1196  322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  811 KEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCL 890
Cdd:COG1196  402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  891 LEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHskLQNAQELMDHDHRTLQDKCDAYEKDklltkhtldCLQSASEELHR 970
Cdd:COG1196  482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAAL--LLAGLRGLAGAVAVLIGVEAAYEAA---------LEAALAAALQN 550

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  971 VKANLDRELKEQDQQLselrerqrEQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATN 1050
Cdd:COG1196  551 IVVEDDEVAAAAIEYL--------KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1051 SSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEA 1130
Cdd:COG1196  623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1131 SEKLAkfdEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKEtqsATATAEVSELKKAI 1210
Cdd:COG1196  703 EEEER---ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL---EELERELERLEREI 776

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....
gi 22024255 1211 EE-QAV------ELTRQKEHASFVTEQSDavqkDLLQAQQQLHD 1247
Cdd:COG1196  777 EAlGPVnllaieEYEELEERYDFLSEQRE----DLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 286-1034 3.73e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 3.73e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    286 LQRLLKERDEQLKS------VTEKYEAVRKQEEE-NVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQ---RESHNN 355
Cdd:TIGR02168  191 LEDILNELERQLKSlerqaeKAERYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAElqeLEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    356 EVKEQFKKLQATKQEVDAKLMATEHLLNTL---KESYAIKEQQVVTLEAQLEAIRVENEQK-------VKDLQKQNEDRN 425
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLeqqKQILRERLANLERQLEELEAQLEELESKldelaeeLAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    426 TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLgklkQENENYLDKLRENKKSSDSQTNEA 505
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI----ERLEARLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    506 QDQQKKlqAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINE 585
Cdd:TIGR02168  427 LKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGF 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    586 LRAAKDEAEAKLLSTEHsLNALQAALSAKEEQAASLE----QSLNALKTESEHSLQD-----------------LRLHND 644
Cdd:TIGR02168  505 SEGVKALLKNQSGLSGI-LGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKaiaflkqnelgrvtflpLDSIKG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    645 QLLEIVQRHQQ------------------------NDWEAQLARAREELAAIQSQRELHALELEKSLEME---RESVAAL 697
Cdd:TIGR02168  584 TEIQGNDREILkniegflgvakdlvkfdpklrkalSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDlvrPGGVITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    698 NSEKASQEEQHR-LKLEQLQREIQILQDQHANSESEtVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQH 776
Cdd:TIGR02168  664 GSAKTNSSILERrREIEELEEKIEELEEKIAELEKA-LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    777 EQHQAKSSDQSARLEALQSELAdrlshsrQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESL 856
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIE-------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    857 QQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHD 936
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    937 HRTLQDKcdayekdklltkhtldcLQSASEELHRvkanLDRELKEQDQQLSELRERQREQEQQLKDQAERCA-------- 1008
Cdd:TIGR02168  896 LEELSEE-----------------LRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeysltle 954

                          810       820
                   ....*....|....*....|....*....
gi 22024255   1009 ---KLKAQNSESETQLQATISNLREQLDA 1034
Cdd:TIGR02168  955 eaeALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 286-856 1.26e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.24  E-value: 1.26e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  286 LQRLLKERDEQLKS------VTEKYEAVRKQEEE---NVLLLA-----QTKQAIHTELELKDTEVRKLQEKLKQLESQRE 351
Cdd:COG1196  191 LEDILGELERQLEPlerqaeKAERYRELKEELKEleaELLLLKlreleAELEELEAELEELEAELEELEAELAELEAELE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  352 SHNNEVKE---QFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR---VENEQKVKDLQKQNEDRN 425
Cdd:COG1196  271 ELRLELEElelELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEeelEELEEELEELEEELEEAE 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  426 TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLD---KLRENKKSSDSQT 502
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErleRLEEELEELEEAL 430

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  503 NEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQ-- 580
Cdd:COG1196  431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgv 510

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  581 --QKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEhsLQDLRLHNDQLLEIVQRHQQNDW 658
Cdd:COG1196  511 kaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY--LKAAKAGRATFLPLDKIRARAAL 588

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  659 EAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALK 738
Cdd:COG1196  589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  739 GQLEALSQDLATSQASLLAKEKELKASgnklnkiKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARV 818
Cdd:COG1196  669 ELLAALLEAEAELEELAERLAEEELEL-------EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 22024255  819 TGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESL 856
Cdd:COG1196  742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 327-922 2.38e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.09  E-value: 2.38e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  327 TELELKDTEVR------KLQEKLKQLES-QREShnnEVKEQFKKLQATKQEVDAKLMA------------TEHLLNTLKE 387
Cdd:COG1196  177 AERKLEATEENlerledILGELERQLEPlERQA---EKAERYRELKEELKELEAELLLlklreleaeleeLEAELEELEA 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  388 SYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNtqasdsseqlkKLQAAVQDAESQLLSKDQLLESLRSEQAAKE 467
Cdd:COG1196  254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEY-----------ELLAELARLEQDIARLEERRRELEERLEELE 322

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  468 QQLKHLKEQLGKLKQEnenyLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALL 547
Cdd:COG1196  323 EELAELEEELEELEEE----LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL 398

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  548 EDKLktlskendvnveklhhinEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNA 627
Cdd:COG1196  399 AAQL------------------EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  628 LKTESEHSLQDLRLHNDQLLEIvqrhqqndwEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQ 707
Cdd:COG1196  461 LLELLAELLEEAALLEAALAEL---------LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  708 HRLKLEQLQREIQILQDQHANSESETVAA-LKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQ 786
Cdd:COG1196  532 VEAAYEAALEAALAAALQNIVVEDDEVAAaAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  787 SARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQvQDSHSELEREKRKLESRIESLQQEQVDSSAQ 866
Cdd:COG1196  612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAERLAE 690

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255  867 DERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDE 922
Cdd:COG1196  691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 292-1109 2.79e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 94.75  E-value: 2.79e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    292 ERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQaihtelelkdtevrklqeKLKQLESQREShnnevKEQFKKLQATKQEV 371
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQ------------------QLERLRREREK-----AERYQALLKEKREY 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    372 DAKLMATEhlLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQdaeSQLLS 451
Cdd:TIGR02169  224 EGYELLKE--KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVK---EKIGE 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    452 KDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEEL-- 529
Cdd:TIGR02169  299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdk 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    530 -LHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQR---EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLN 605
Cdd:TIGR02169  379 eFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELadlNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    606 ALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREE-----LAAIQSQRELHA 680
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    681 LELE-------KSLEMERESVAALNSEKASQEEQHRL------KLEQLQREI---------------------------Q 720
Cdd:TIGR02169  539 TAIEvaagnrlNNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLsilsedgvigfavdlvefdpkyepafkY 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    721 ILQDQHANSESETVAALKGQLEalsqdLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADR 800
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYR-----MVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    801 LSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSE 880
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    881 NTKLAERNCLLEEQTNH-----LESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTK 955
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHsripeIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    956 HTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESE---TQLQATISNLREQL 1032
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRkrlSELKAKLEALEEEL 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1033 DAYKQTEQGIQE---------KLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKikhgQEREEVKESI 1103
Cdd:TIGR02169  934 SEIEDPKGEDEEipeeelsleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLE----EERKAILERI 1009


                   ....*.
gi 22024255   1104 AQKNRQ 1109
Cdd:TIGR02169 1010 EEYEKK 1015
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 401-1145 6.34e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 6.34e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    401 AQLEAIRVENEQKVKDLQKQnedrntqaSDSSEQLKKLQAAVQDAESQLLSKDqlLESLRSEQAAKEQQLKHLKEQLGKL 480
Cdd:TIGR02168  189 DRLEDILNELERQLKSLERQ--------AEKAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    481 KQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAK---DEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKE 557
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALAneiSRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    558 NDVNVEKLHHINEQREAQstdsQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLE---QSLNALKTESEH 634
Cdd:TIGR02168  339 LAELEEKLEELKEELESL----EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNneiERLEARLERLED 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    635 SLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKaSQEEQHRLKLEQ 714
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE-RELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    715 LQR-----------EIQILQDQHANS----------------ESETVAALKGQLEAL---SQDLATSQASLLAKEKELKA 764
Cdd:TIGR02168  494 LERlqenlegfsegVKALLKNQSGLSgilgvlselisvdegyEAAIEAALGGRLQAVvveNLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    765 --------SGNKLNK----IKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEEL-QARVTGILEEIGTMQAQ 831
Cdd:TIGR02168  574 tflpldsiKGTEIQGndreILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALeLAKKLRPGYRIVTLDGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    832 M---------QQVQDSHSELEREK--RKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLES 900
Cdd:TIGR02168  654 LvrpggvitgGSAKTNSSILERRReiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    901 QLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELK 980
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    981 EQD---QQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNssytTQI 1057
Cdd:TIGR02168  814 LLNeeaANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLE----EAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1058 ATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQ---EREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKL 1134
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQlelRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          810
                   ....*....|.
gi 22024255   1135 AKFDEILIENE 1145
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 541-1343 1.22e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.82  E-value: 1.22e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    541 EEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKI--NELRAAKDEAEAKLL-----STEHSLNALQAALSA 613
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAEryQALLKEKREYEGYELlkekeALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    614 KEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQrHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERES 693
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE-EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    694 VAALNSEKASQEEQHRlKLEQLQREIQILQDQHANSEsETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIK 773
Cdd:TIGR02169  328 EAEIDKLLAEIEELER-EIEEERKRRDKLTEEYAELK-EELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    774 KQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRI 853
Cdd:TIGR02169  406 RELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    854 ESLQQE------QVDSSAQDERTSAKLEEIQSENTK-----LAERNCLLEEQTNHLES----QLQAKQDEIGKIQAKLQQ 918
Cdd:TIGR02169  486 SKLQRElaeaeaQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnRLNNVVVEDDAVAKEAIE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    919 VLDEH----------SKLQNAQELMDHDHRT--------LQDKCDAYEKD-KLLTKHTL--DCLQSASEELHRVK-ANLD 976
Cdd:TIGR02169  566 LLKRRkagratflplNKMRDERRDLSILSEDgvigfavdLVEFDPKYEPAfKYVFGDTLvvEDIEAARRLMGKYRmVTLE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    977 RELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQldaykqtEQGIQEKLQATnSSYTTQ 1056
Cdd:TIGR02169  646 GELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI-------ENRLDELSQEL-SDASRK 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1057 IATLEARWSAANSDVERLHEANDALQLEMEQLKikhgQEREEVKESIAQKNRQVVELQEAMATRDRQLqEKIEASEKLAK 1136
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE----QEIENVKSELKELEARIEELEEDLHKLEEAL-NDLEARLSHSR 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1137 FDEILIENEYLNKHTKQLEAELaesAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVE 1216
Cdd:TIGR02169  793 IPEIQAELSKLEEEVSRIEARL---REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1217 LtrqKEHASFVTE----------QSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICL----KEHLSP 1282
Cdd:TIGR02169  870 L---EELEAALRDlesrlgdlkkERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIedpkGEDEEI 946

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22024255   1283 STDSDSLRSLNERLQRELEDLkhkSAGAESNMQ--QEIEELQANNQQMAERINELETLRAGIQ 1343
Cdd:TIGR02169  947 PEEELSLEDVQAELQRVEEEI---RALEPVNMLaiQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 456-1034 6.33e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.38  E-value: 6.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  456 LESLRsEQAAKEQQLKHLKEQLGKLKQE-NENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLR 534
Cdd:COG1196  202 LEPLE-RQAEKAERYRELKEELKELEAElLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  535 NDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQRE---AQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAAL 611
Cdd:COG1196  281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEeleEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  612 SAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNdwEAQLARAREELAAIQSQRELHALELEKSLEmER 691
Cdd:COG1196  361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL--EEAEEALLERLERLEEELEELEEALAELEE-EE 437

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  692 ESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLAtsQASLLAKEKELKASGNKLNK 771
Cdd:COG1196  438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL--LLEAEADYEGFLEGVKAALL 515

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  772 IKKQHEQHQAKSSDQS--ARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIG--TMQAQMQQVQDSHSELEREKR 847
Cdd:COG1196  516 LAGLRGLAGAVAVLIGveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGraTFLPLDKIRARAALAAALARG 595

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  848 KLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQ 927
Cdd:COG1196  596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  928 NAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAErc 1007
Cdd:COG1196  676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL-- 753

                        570       580
                 ....*....|....*....|....*..
gi 22024255 1008 akLKAQNSESETQLQATISNLREQLDA 1034
Cdd:COG1196  754 --EELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 170-764 1.14e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.23  E-value: 1.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  170 AKKYKELERDSSKARSVLvetqdkALRRISELREQCTLEQQAKAHLEEALRVEMDdmscKMQAYQTKLQLLGENPENITA 249
Cdd:COG1196  212 AERYRELKEELKELEAEL------LLLKLRELEAELEELEAELEELEAELEELEA----ELAELEAELEELRLELEELEL 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  250 ALERSGQQLE--SEQLIDLEESIgksplstngssgvsdlqRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHT 327
Cdd:COG1196  282 ELEEAQAEEYelLAELARLEQDI-----------------ARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  328 ELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR 407
Cdd:COG1196  345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  408 VENEQKVKDLQKQNEDRNTQASDSSEQLkKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENY 487
Cdd:COG1196  425 ELEEALAELEEEEEEEEEALEEAAEEEA-ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  488 LDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELlhSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHH 567
Cdd:COG1196  504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  568 INEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLL 647
Cdd:COG1196  582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  648 EIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHA 727
Cdd:COG1196  662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                        570       580       590
                 ....*....|....*....|....*....|....*..
gi 22024255  728 NSESETVAALKGQLEALSQDLATSQASLLAKEKELKA 764
Cdd:COG1196  742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 757-1344 5.91e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 5.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  757 AKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQ 836
Cdd:COG1196  222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  837 DSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKL 916
Cdd:COG1196  302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  917 QQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQ 996
Cdd:COG1196  382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  997 EQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTE---QGIQEKLQATNSSYTTQIATLEARWSAANSDVER 1073
Cdd:COG1196  462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1074 LHEANDALQLEMEQLkikhGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKLAKFDEILIENEYLNKHTKQ 1153
Cdd:COG1196  542 AALAAALQNIVVEDD----EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1154 LEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDA 1233
Cdd:COG1196  618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1234 VQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEViclkehlspstdsdslrslnERLQRELEDLKHKSAGAESN 1313
Cdd:COG1196  698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL--------------------LEELLEEEELLEEEALEELP 757

                        570       580       590
                 ....*....|....*....|....*....|.
gi 22024255 1314 MQQEIEELQAnnqqmaerinELETLRAGIQA 1344
Cdd:COG1196  758 EPPDLEELER----------ELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 511-1336 1.03e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.03e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    511 KLQAAKDEAESKLLATEELLhslrndykaqeekvalleDKLKTLSKENDVNVEKLhhineQREAQSTdsqQKINELRAAK 590
Cdd:TIGR02168  169 KYKERRKETERKLERTRENL------------------DRLEDILNELERQLKSL-----ERQAEKA---ERYKELKAEL 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    591 DEAEAKLLSTEhsLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRhqQNDWEAQLARAREELA 670
Cdd:TIGR02168  223 RELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE--IEELQKELYALANEIS 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    671 AIQSQRELHALELEkSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHAnSESETVAALKGQLEALSQDLAT 750
Cdd:TIGR02168  299 RLEQQKQILRERLA-NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELESRLEE 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    751 SQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLShsRQVESEKEELQARVTGILEEIGTMQA 830
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    831 QmqqvqdsHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLaernclleEQTNHLESQLQAKQDEIG 910
Cdd:TIGR02168  455 E-------LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL--------EGFSEGVKALLKNQSGLS 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    911 KIQAKLQQVLDEHSKLQNA-----QELMDH---DHRTLQDKCDAYEKDKLLTKHTLDCLQSASEElhRVKANLDRELKEQ 982
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAieaalGGRLQAvvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT--EIQGNDREILKNI 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    983 DQQLSELRERQREQEQQLK---------------DQAERCAKLKAQNSESETQ---------LQATISNLREQLDAYKQT 1038
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRKalsyllggvlvvddlDNALELAKKLRPGYRIVTLdgdlvrpggVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1039 E----QGIQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQ 1114
Cdd:TIGR02168  678 EieelEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1115 EAMATRDRQLQEKIEASEKLAKF-DEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKE 1193
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1194 TQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEV 1273
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22024255   1274 ICLKEHLSpstdsdSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANN----QQMAERINELE 1336
Cdd:TIGR02168  918 EELREKLA------QLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIeddeEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 250-918 4.41e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 4.41e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    250 ALERSGQQLESeQLIDLEESIGKSP--LSTNGSSgVSDLQRLLKERDEQLKSVTE-KYEAVRKQEEENVLLLAQTKQAIh 326
Cdd:TIGR02169  234 ALERQKEAIER-QLASLEEELEKLTeeISELEKR-LEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSI- 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    327 telELKDTEVRKLQEKLKQLESQRESHNNEVkEQFKKLQATKQEVDAKLMATehlLNTLKESYAIKEQQVVTLEAQLEAI 406
Cdd:TIGR02169  311 ---AEKERELEDAEERLAKLEAEIDKLLAEI-EELEREIEEERKRRDKLTEE---YAELKEELEDLRAELEEVDKEFAET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    407 RVENEQKVKDLQKQNEDRN----------TQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQ 476
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINelkreldrlqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    477 LGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDY-------KAQEEKVALLE- 548
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHgtvaqlgSVGERYATAIEv 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    549 ---DKLKTLSKENDVNVEKLHHINEQREAqSTDSQQKINELRAakdeaEAKLLSTEHSLNALQAALSAKE---------- 615
Cdd:TIGR02169  544 aagNRLNNVVVEDDAVAKEAIELLKRRKA-GRATFLPLNKMRD-----ERRDLSILSEDGVIGFAVDLVEfdpkyepafk 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    616 ------------EQAASLEQSLNALKTESE----------HSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQ 673
Cdd:TIGR02169  618 yvfgdtlvvediEAARRLMGKYRMVTLEGElfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    674 SQRELHALELEKSLEMERESVAALNSEK---ASQEEQHRLKLEQLQREIQILQDQHANSESEtVAALKGQLEALSQDLAT 750
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIeqlEQEEEKLKERLEELEEDLSSLEQEIENVKSE-LKELEARIEELEEDLHK 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    751 SQASLLAKEKELkaSGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQA 830
Cdd:TIGR02169  777 LEEALNDLEARL--SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    831 QMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIG 910
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934


                   ....*...
gi 22024255    911 KIQAKLQQ 918
Cdd:TIGR02169  935 EIEDPKGE 942
PTZ00121 PTZ00121
MAEBL; Provisional
 303-948 6.15e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 6.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   303 KYEAVRKQEEenvllLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKlmatehll 382
Cdd:PTZ00121 1183 KAEEVRKAEE-----LRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER-------- 1249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   383 nTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQllSKDQLLESLRSE 462
Cdd:PTZ00121 1250 -NNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA--KKADEAKKKAEE 1326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   463 QAAKEQQLKHLKEQLGK----LKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEEllhslrnDYK 538
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKaaeaAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA-------KKK 1399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   539 AQEEKVALLEDKLKTLSKENDVNVEKlhhinEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQA 618
Cdd:PTZ00121 1400 AEEDKKKADELKKAAAAKKKADEAKK-----KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   619 ASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALN 698
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   699 SEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNK---IKKQ 775
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKaeeEKKK 1634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   776 HEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVtgilEEIGTMQAQMQQVQDSHSELEREKRKLEsRIES 855
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKK 1709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   856 LQQEQVDSSAQ----DERTSAKLEEIQ---SENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQN 928
Cdd:PTZ00121 1710 KEAEEKKKAEElkkaEEENKIKAEEAKkeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789

                         650       660
                  ....*....|....*....|
gi 22024255   929 AQELMDHDhRTLQDKCDAYE 948
Cdd:PTZ00121 1790 EKRRMEVD-KKIKDIFDNFA 1808
PTZ00121 PTZ00121
MAEBL; Provisional
 146-869 7.40e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.49  E-value: 7.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   146 DQLYDAYKKSLDRYHKYRCRYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAH-LEEALRVEMD 224
Cdd:PTZ00121 1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARkAEDARKAEEA 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   225 ---DMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESigKSPLSTNGSSGVSDLQRLLKERDEQLKSVT 301
Cdd:PTZ00121 1170 rkaEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEA--RKAEDAKKAEAVKKAEEAKKDAEEAKKAEE 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   302 EK-YEAVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMATEh 380
Cdd:PTZ00121 1248 ERnNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE- 1326

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   381 llnTLKESYAIKEQQVVTLEAQlEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQllSKDQLLESLR 460
Cdd:PTZ00121 1327 ---AKKKADAAKKKAEEAKKAA-EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK--KKADEAKKKA 1400

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   461 SEQAAKEQQLKHLKEQLGKLKQenenyLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKllATEELLHSLRNDYKAQ 540
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKADE-----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK--KAEEAKKKAEEAKKAD 1473

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   541 EEKVALLE----DKLKTLSKENDVNVEKLHHINEQR----EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALS 612
Cdd:PTZ00121 1474 EAKKKAEEakkaDEAKKKAEEAKKKADEAKKAAEAKkkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   613 AKEEQAASLEQSLNALKTESEHSLQDLRlhndqlleivqrhqqndwEAQLARAREELAAIQSQRELHALELEKSLEMERE 692
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALR------------------KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   693 SVAALNSEKASQEEQHRLKLEQLQR--EIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLN 770
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKkeAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   771 KI---KKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVtgilEEIGTMQAQMQQVQDSHSELEREKR 847
Cdd:PTZ00121 1696 KEaeeAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA----EEAKKDEEEKKKIAHLKKEEEKKAE 1771

                         730       740
                  ....*....|....*....|..
gi 22024255   848 KLESRIESLQQEQVDSSAQDER 869
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRR 1793
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 841-1349 4.73e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 4.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  841 ELEREKRKLESRIESLQQEQVDssAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVL 920
Cdd:COG1196  217 ELKEELKELEAELLLLKLRELE--AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  921 DEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQL 1000
Cdd:COG1196  295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1001 KDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDA 1080
Cdd:COG1196  375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1081 LQLEMEQL--------KIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKLAKFDEILIENEYLNKHTK 1152
Cdd:COG1196  455 EEEEEALLellaelleEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1153 QLEAELAESAElkeklksLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSD 1232
Cdd:COG1196  535 AYEAALEAALA-------AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1233 AVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICLKEHLSPSTDSDSLRSLNERLQRELEDLKHKSAGAES 1312
Cdd:COG1196  608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 22024255 1313 NMQQEIEELQANNQQMAERINELETLRAGIQAQQLLA 1349
Cdd:COG1196  688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 659-1421 3.02e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 3.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    659 EAQLARAREELAAIQSQRElhalELEKSLE-MERESvaalnsEKASQEEQHRLKLEQLQREIQILQdqhansesetVAAL 737
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILN----ELERQLKsLERQA------EKAERYKELKAELRELELALLVLR----------LEEL 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    738 KGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADrlshsrqVESEKEELQAR 817
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR-------LEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    818 VTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQvdssaqdERTSAKLEEIQSENTKLAERNCLLEEQTNH 897
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL-------ESLEAELEELEAELEELESRLEELEEQLET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    898 LESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDayEKDKLLTKHTLDCLQSASEELHRVKANLDR 977
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    978 ELKEQDQQLSELRERQREQEQQLKDQAERCAKLKA--QNSESETQLQATISNLREQLDAYKQTeqgIQEKLQATNSSYTT 1055
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERlqENLEGFSEGVKALLKNQSGLSGILGV---LSELISVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1056 QIATLEARW--------SAANSDVERLHEANDALQLEMEqLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEK 1127
Cdd:TIGR02168  539 IEAALGGRLqavvvenlNAAKKAIAFLKQNELGRVTFLP-LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1128 IEA-------SEKLAKFDEILIENEY-----------------------------------LNKHTKQLEAELAESAELK 1165
Cdd:TIGR02168  618 LSYllggvlvVDDLDNALELAKKLRPgyrivtldgdlvrpggvitggsaktnssilerrreIEELEEKIEELEEKIAELE 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1166 EKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQsdavqkdLLQAQQQL 1245
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE-------IEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1246 HDKQIELAMSRDEQALLQAEADGLRQEVICLKEHLSP-----STDSDSLRSLNERLQRELEDLKHKSAGAEsNMQQEIEE 1320
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDElraelTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1321 LQANNQQMAERINELETLRAGIQAQ--QLLASMAPKNVQEAAAAGEKAELESKLKEIMNEVQDvtnrnlfLEQKCENfli 1398
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESEleALLNERASLEEALALLRSELEELSEELRELESKRSE-------LRRELEE--- 919

                          810       820
                   ....*....|....*....|...
gi 22024255   1399 LEQSNERLKLQNAKLSRQLDETL 1421
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQ 942
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 201-921 3.04e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.69  E-value: 3.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    201 LREQCTLEQQAKAHLEEA---LRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIdleesigKSPLST 277
Cdd:pfam15921   94 LNESNELHEKQKFYLRQSvidLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCL-------KEDMLE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    278 NGSSGVSDLQRLLKERD---EQLKSVTEKYE-----AVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQ 349
Cdd:pfam15921  167 DSNTQIEQLRKMMLSHEgvlQEIRSILVDFEeasgkKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQ 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    350 RESHNNEVKEQFKKLQATKQEVDAKLMATEHL-LNTLKESYAIKEQQVVTLEAQLEAI----RVENEQKVKDLQKQNEDR 424
Cdd:pfam15921  247 LEALKSESQNKIELLLQQHQDRIEQLISEHEVeITGLTEKASSARSQANSIQSQLEIIqeqaRNQNSMYMRQLSDLESTV 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    425 NTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKL-----KQENENYLDKlRENKKSSD 499
Cdd:pfam15921  327 SQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhKREKELSLEK-EQNKRLWD 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    500 SQTNEAQDQQKkLQAAKDEAESKLLATEELLHSLRNDYKAQ-EEKVALLEDKLKTLskendvnvEKLHHINEQREAQSTD 578
Cdd:pfam15921  406 RDTGNSITIDH-LRRELDDRNMEVQRLEALLKAMKSECQGQmERQMAAIQGKNESL--------EKVSSLTAQLESTKEM 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    579 SQQKINELRAAKDEAEakllSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIvqRHQQNDW 658
Cdd:pfam15921  477 LRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL--RNVQTEC 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    659 EAQLARAREELAAIQSQRElHALELEKSLEMERESVAALNSEKASQEEQ---HRLKLEQLQ-------REIQILQDQHAN 728
Cdd:pfam15921  551 EALKLQMAEKDKVIEILRQ-QIENMTQLVGQHGRTAGAMQVEKAQLEKEindRRLELQEFKilkdkkdAKIRELEARVSD 629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    729 SESETVAALKGQLEALS--QDLATSQASLLakeKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLShSRQ 806
Cdd:pfam15921  630 LELEKVKLVNAGSERLRavKDIKQERDQLL---NEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK-SAQ 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    807 VESEKEE-------------------LQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQD 867
Cdd:pfam15921  706 SELEQTRntlksmegsdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255    868 ERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGK-----IQAKLQQVLD 921
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRqeqesVRLKLQHTLD 844
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 328-1346 5.68e-12

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 70.97  E-value: 5.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    328 ELELKDTEVRKLQEKLKQLESqreshnnevkeQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQqvvtLEAQLEAIR 407
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAES-----------ELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARK 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    408 VENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLkqeneny 487
Cdd:pfam01576   71 QELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL------- 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    488 ldklrenkkssDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENdvnvEKLHH 567
Cdd:pfam01576  144 -----------EDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGR----QELEK 208

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    568 INEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALsaKEEQAAsleqslnalKTESEHSLQDLRLHNDQLL 647
Cdd:pfam01576  209 AKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARL--EEETAQ---------KNNALKKIRELEAQISELQ 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    648 EIVQRHQQndweaqlARAREELAAIQSQRELHALELEksLEMERESVAALNSEKASQEEQhrlkLEQLQREIQILQDQHA 727
Cdd:pfam01576  278 EDLESERA-------ARNKAEKQRRDLGEELEALKTE--LEDTLDTTAAQQELRSKREQE----VTELKKALEEETRSHE 344

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    728 NSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQV 807
Cdd:pfam01576  345 AQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSES 424

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    808 ESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAER 887
Cdd:pfam01576  425 ERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQ 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    888 NCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVL-------DEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDC 960
Cdd:pfam01576  505 LEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAgtlealeEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDD 584

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    961 LQSASEELHRVKANLDRELKEQDQQLSeLRERQREQEQQLKDQAERCAKlkaqnsESETQLQATISNLREQLDAykqteq 1040
Cdd:pfam01576  585 LLVDLDHQRQLVSNLEKKQKKFDQMLA-EEKAISARYAEERDRAEAEAR------EKETRALSLARALEEALEA------ 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1041 giQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATR 1120
Cdd:pfam01576  652 --KEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQF 729

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1121 DRQLQEKIEASEKLAKfdeilieneYLNKHTKQLEAELAESAELKEKL----KSLQCELYVLQEKAEQHAVQMAEKETQS 1196
Cdd:pfam01576  730 ERDLQARDEQGEEKRR---------QLVKQVRELEAELEDERKQRAQAvaakKKLELDLKELEAQIDAANKGREEAVKQL 800

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1197 ATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQqlhdkqiELAMSRDEQALLQAEADGLRQEVIcl 1276
Cdd:pfam01576  801 KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQE-------DLAASERARRQAQQERDELADEIA-- 871

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1277 kehlSPSTDSDSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQ 1346
Cdd:pfam01576  872 ----SGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSE 937
PTZ00121 PTZ00121
MAEBL; Provisional
 294-1002 9.26e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.56  E-value: 9.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   294 DEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHTELELKDTE-------VRKLQEKLKQLESQRESHNNEVKEQFKKLQA 366
Cdd:PTZ00121 1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEearkaedARKAEEARKAEDAKRVEIARKAEDARKAEEA 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   367 TKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEaqlEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAE 446
Cdd:PTZ00121 1170 RKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE---AARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   447 sqllsKDQLLESLRSEQaakEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLAT 526
Cdd:PTZ00121 1247 -----EERNNEEIRKFE---EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD 1318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   527 EEllhslrnDYKAQEEKvalledklktlsKENDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNA 606
Cdd:PTZ00121 1319 EA-------KKKAEEAK------------KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   607 LQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKS 686
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   687 LEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASG 766
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   767 NKLNKIKKQHEQHQA---KSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGIL---EEIGTMQAQmQQVQDSHS 840
Cdd:PTZ00121 1540 KKAEEKKKADELKKAeelKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMklyEEEKKMKAE-EAKKAEEA 1618

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   841 ELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVL 920
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   921 DEHSKLQNAQELMDHDHRtlqdKCDAYEKDKLLTKHTLDCLQSASEELHRV--KANLDRELKEQDQQLSELRERQREQEQ 998
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKK----KAEELKKAEEENKIKAEEAKKEAEEDKKKaeEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774


                  ....
gi 22024255   999 QLKD 1002
Cdd:PTZ00121 1775 KEKE 1778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
283-744 2.93e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.53  E-value: 2.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   283 VSDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAiHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFK 362
Cdd:PRK02224  208 LNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER-REELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   363 KLQATKQEVDAKLMATEhlLNTLKESYAikEQQVVTLEAQLEAIRVENEQKVKDLQKQNE----------DRNTQASDSS 432
Cdd:PRK02224  287 RLEELEEERDDLLAEAG--LDDADAEAV--EARREELEDRDEELRDRLEECRVAAQAHNEeaeslredadDLEERAEELR 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   433 EQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENY---LDKLRENKKSSDSQTNEAQDQQ 509
Cdd:PRK02224  363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELreeRDELREREAELEATLRTARERV 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   510 KKLQA---------------------AKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDV--NVEKLH 566
Cdd:PRK02224  443 EEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLeeRREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   567 HINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEhSLQDLRlhnDQL 646
Cdd:PRK02224  523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIR---TLL 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   647 LEIvqrhqqNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEK--ASQEEQHRLK--LEQLQREIQIL 722
Cdd:PRK02224  599 AAI------ADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARieEAREDKERAEeyLEQVEEKLDEL 672

                         490       500
                  ....*....|....*....|..
gi 22024255   723 QDQHANSESEtVAALKGQLEAL 744
Cdd:PRK02224  673 REERDDLQAE-IGAVENELEEL 693
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 760-1438 4.12e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 4.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    760 KELKASGNKLNKIKKQHEQHQAKSSD-QSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDS 838
Cdd:TIGR02168  196 NELERQLKSLERQAEKAERYKELKAElRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    839 HSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQ 918
Cdd:TIGR02168  276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    919 VLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDC----LQSASEELHRVKANLDRELKEQDQQLSelrerqR 994
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASlnneIERLEARLERLEDRRERLQQEIEELLK------K 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    995 EQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQatnssyttQIATLEARWSAANSDVERL 1074
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER--------ELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1075 HEANDAL-QLEMEQLKIKHGQEREEVKESIAQKNRQVVE--LQEAM---ATRDRQLQEKIEASEKLAKFDEILIENEYLN 1148
Cdd:TIGR02168  502 EGFSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEaaLGGRLqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1149 KHTKqLEAELAESAELKEKLKSLQCELYVLQEKAE----------------QHAVQMAEKET------------------ 1194
Cdd:TIGR02168  582 KGTE-IQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddlDNALELAKKLRpgyrivtldgdlvrpggv 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1195 ---QSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQ 1271
Cdd:TIGR02168  661 itgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1272 EVICLKEhlspstDSDSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQLLASM 1351
Cdd:TIGR02168  741 EVEQLEE------RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1352 APKNVQEAAAAGEKAELESKLKEIMNEVQDVTnrnlfLEQKCENFLILEQSNERLKLQNAKLSRQLDETLVSMQHSEAVP 1431
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQ-----IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889


                   ....*..
gi 22024255   1432 ANTEFEY 1438
Cdd:TIGR02168  890 ALLRSEL 896
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 788-1375 4.41e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 4.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  788 ARLEALQSELADRLSH-SRQVE---------SEKEELQARVTGileeigtmqAQMQQVQDSHSELEREKRKLESRIESLQ 857
Cdd:COG1196  189 ERLEDILGELERQLEPlERQAEkaeryrelkEELKELEAELLL---------LKLRELEAELEELEAELEELEAELEELE 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  858 QEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDH 937
Cdd:COG1196  260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  938 RTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSES 1017
Cdd:COG1196  340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1018 ETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQERE 1097
Cdd:COG1196  420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1098 EVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKLAKFDEILIENEYLNKHTKQLEAELAESAELKEKLKSLQcELYV 1177
Cdd:COG1196  500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA-TFLP 578

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1178 LQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRD 1257
Cdd:COG1196  579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1258 EQALLQAEADGLRQEVICLKEHLSPSTDSDSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANNQQMAERINELET 1337
Cdd:COG1196  659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                        570       580       590
                 ....*....|....*....|....*....|....*...
gi 22024255 1338 LRAGIQAQQLLASMAPKNVQEAAAAGEKAELESKLKEI 1375
Cdd:COG1196  739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
295-919 5.95e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 67.63  E-value: 5.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  295 EQLKSVTEKYEAVRKQEEENVLLLAQ-TKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEV-D 372
Cdd:COG4913  255 EPIRELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrG 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  373 AKLMATEHLlntlkesyaikEQQVVTLEAQLEAIrvenEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLlsk 452
Cdd:COG4913  335 NGGDRLEQL-----------EREIERLERELEER----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEAL--- 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  453 DQLLESLRSEQAAKEQQLKHLKEQLGKLKQEnenyLDKLRENKKSSDSQTNEAQDQQKKlQAAKDEAESKLL-------- 524
Cdd:COG4913  397 EEELEALEEALAEAEAALRDLRRELRELEAE----IASLERRKSNIPARLLALRDALAE-ALGLDEAELPFVgelievrp 471

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  525 -------ATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKL 597
Cdd:COG4913  472 eeerwrgAIERVLGGFALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWL 551

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  598 lstehslnalqaalsakeeqAASLEQSLNALKTESEHSLQDLRL---------HNDQLLEI-VQRHQQNDW------EAQ 661
Cdd:COG4913  552 --------------------EAELGRRFDYVCVDSPEELRRHPRaitragqvkGNGTRHEKdDRRRIRSRYvlgfdnRAK 611

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  662 LARAREELAAIQSQRELHALELEKsLEMERESVAALNS--EKASQEEQHRLKLEQLQREIQILQDQHAN--SESETVAAL 737
Cdd:COG4913  612 LAALEAELAELEEELAEAEERLEA-LEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERldASSDDLAAL 690

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  738 KGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRlshsRQVESEKEELQAR 817
Cdd:COG4913  691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----RFAAALGDAVERE 766

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  818 VTGILEEigtmqaqmqQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNC-------- 889
Cdd:COG4913  767 LRENLEE---------RIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGLpeyeerfk 837

                        650       660       670
                 ....*....|....*....|....*....|..
gi 22024255  890 -LLEEQTNHLESQLQAK-QDEIGKIQAKLQQV 919
Cdd:COG4913  838 eLLNENSIEFVADLLSKlRRAIREIKERIDPL 869
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 285-942 6.22e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 67.56  E-value: 6.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    285 DLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAqtkqaiHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKL 364
Cdd:pfam12128  222 QVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESA------ELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTL 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    365 QATKQEVDAKLMATehlLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQD 444
Cdd:pfam12128  296 DDQWKEKRDELNGE---LSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQD 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    445 AESqllsKDQLLESLRSEQAAK-----EQQLKHLKEQLGKLKQENENYLDKL-RENKKSSDSQTNEAQDQQKKLQAAKDE 518
Cdd:pfam12128  373 VTA----KYNRRRSKIKEQNNRdiagiKDKLAKIREARDRQLAVAEDDLQALeSELREQLEAGKLEFNEEEYRLKSRLGE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    519 AESKL---LATEELLHSLRNdykaqeekvalledklktlskeNDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEA 595
Cdd:pfam12128  449 LKLRLnqaTATPELLLQLEN----------------------FDERIERAREEQEAANAEVERLQSELRQARKRRDQASE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    596 KLLSTEHSLNALQAALSAKEEQ---------------AASLEQSL------------------NALKTESEHSLQDLRLH 642
Cdd:pfam12128  507 ALRQASRRLEERQSALDELELQlfpqagtllhflrkeAPDWEQSIgkvispellhrtdldpevWDGSVGGELNLYGVKLD 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    643 ndqlleiVQRHQQNDWEAQLARAREELA----AIQSQRELHAlELEKSLEMERESVAALNSEK---ASQEEQHRLKLEQL 715
Cdd:pfam12128  587 -------LKRIDVPEWAASEEELRERLDkaeeALQSAREKQA-AAEEQLVQANGELEKASREEtfaRTALKNARLDLRRL 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    716 QREIQILQDQHAnsesetvaalkgqlEALSQDLATSQASLLAKEKELKASGNKLNKIKK-QHEQHQAKSSDQSARLEALQ 794
Cdd:pfam12128  659 FDEKQSEKDKKN--------------KALAERKDSANERLNSLEAQLKQLDKKHQAWLEeQKEQKREARTEKQAYWQVVE 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    795 SELADRLSH-SRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQeqvdssaqdeRTSAK 873
Cdd:pfam12128  725 GALDAQLALlKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV----------RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22024255    874 LEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQA----KLQQVLDEHSKLQNAQELMDHDHRTLQD 942
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIAdtklRRAKLEMERKASEKQQVRLSENLRGLRC 867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 700-1419 7.00e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 7.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    700 EKASQE-EQHRLKLEQLQREIQILQDQHANSESETVAALKGQleALSQDLATSQASLLAKEKE-----LKASGNKLNKIK 773
Cdd:TIGR02169  173 EKALEElEEVEENIERLDLIIDEKRQQLERLRREREKAERYQ--ALLKEKREYEGYELLKEKEalerqKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    774 KQHEQHQAKSSDQSARLEALQSELADRlshSRQVESEKEELQARVTgilEEIGTMQAQMQQVQDSHSELEREKRKLESRI 853
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEEL---NKKIKDLGEEEQLRVK---EKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    854 ESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELM 933
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    934 DHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQ 1013
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1014 NSESETQL---QATISNLREQLDAYKQTEQGIQEKLQATNSSyTTQIATLEARWSAA----------NSDVERLHEANDA 1080
Cdd:TIGR02169  485 LSKLQRELaeaEAQARASEERVRGGRAVEEVLKASIQGVHGT-VAQLGSVGERYATAievaagnrlnNVVVEDDAVAKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1081 LQ------------LEMEQLKIKHGQEREEVKESIAQKNRQVVELQE------AMATRDRQLQEKIEASEKL-AKFDEIL 1141
Cdd:TIGR02169  564 IEllkrrkagratfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPkyepafKYVFGDTLVVEDIEAARRLmGKYRMVT 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1142 IENEYLNKH------TKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAV 1215
Cdd:TIGR02169  644 LEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1216 ELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICLKEHLSPS---TDSDSLRSL 1292
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripEIQAELSKL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1293 NERLQRELEDLKHKSAgAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQ--LLASMAPKNVQEAAAAGEKAELES 1370
Cdd:TIGR02169  804 EEEVSRIEARLREIEQ-KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIenLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 22024255   1371 KLKEIMNEVQDVTNRNLFLEQKCENFLI-LEQSNERLKLQNAKLSRQLDE 1419
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAqIEKKRKRLSELKAKLEALEEE 932
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1433-1477 5.28e-10

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 56.07  E-value: 5.28e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 22024255    1433 NTEFEYLRNIMFQYLTGNTN-NETLVKVISAVLKFSPQQAQVALEK 1477
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESeRETLLPVISTVLQLSPEEMQKLLEV 46
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
660-1334 1.08e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.40  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  660 AQLARAREELAAIQSQRELhaleLEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESEtVAALKG 739
Cdd:COG4913  235 DDLERAHEALEDAREQIEL----LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAE-LARLEA 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  740 QLEALSQDLATSQASLL-AKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQsELADRLSHSrqVESEKEELQARV 818
Cdd:COG4913  310 ELERLEARLDALREELDeLEAQIRGNGGDRLEQLEREIERLERELEERERRRARLE-ALLAALGLP--LPASAEEFAALR 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  819 TGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSEntklaernclleeqtnhL 898
Cdd:COG4913  387 AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA-----------------L 449

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  899 ESQLQAKQDEIgKIQAKLQQVLDEHSKLQNAQELMDHDHRT--------LQDKCDAYEKDKLLTKHTLDCLQSASEELHR 970
Cdd:COG4913  450 AEALGLDEAEL-PFVGELIEVRPEEERWRGAIERVLGGFALtllvppehYAAALRWVNRLHLRGRLVYERVRTGLPDPER 528

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  971 VKAnldrelkeQDQQLSelrerqreqeqqlkdqaercAKLKAQNSESETQLQATISNLR-----EQLDAYKQTEQGIQEK 1045
Cdd:COG4913  529 PRL--------DPDSLA--------------------GKLDFKPHPFRAWLEAELGRRFdyvcvDSPEELRRHPRAITRA 580

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1046 LQATNSSyttqiatlearwsaansdveRLHEANDALQLE---------MEQLKIKHgQEREEVKESIAQKNRQVVELQEA 1116
Cdd:COG4913  581 GQVKGNG--------------------TRHEKDDRRRIRsryvlgfdnRAKLAALE-AELAELEEELAEAEERLEALEAE 639

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1117 MatrdRQLQEKIEASEKLAKFDEILIEneylnkhTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQS 1196
Cdd:COG4913  640 L----DALQERREALQRLAEYSWDEID-------VASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEEL 708

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1197 ATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQ-QQLHDKQIELAMSR---DEQALLQAEADGLRQE 1272
Cdd:COG4913  709 DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfAAALGDAVERELREnleERIDALRARLNRAEEE 788

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255 1273 VI-CLKEHLS--------PSTDSDSLRSLNERLQR----ELEDLKHKSAGA-ESNMQQEIEELQANNQQMAERINE 1334
Cdd:COG4913  789 LErAMRAFNRewpaetadLDADLESLPEYLALLDRleedGLPEYEERFKELlNENSIEFVADLLSKLRRAIREIKE 864
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 282-1049 1.20e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.21  E-value: 1.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    282 GVSDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHTELElkdtevrKLQEKLKQLESQRESHNNEVKEQF 361
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQ-------EMQMERDAMADIRRRESQSQEDLR 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    362 KKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR---VENEQKVKDLQKQNEDRNT-----QASDSSE 433
Cdd:pfam15921  145 NQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRsilVDFEEASGKKIYEHDSMSTmhfrsLGSAISK 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    434 QLKKLQAAVQDAESQLLSKDQLLESLRSEQAAK-EQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKL 512
Cdd:pfam15921  225 ILRELDTEISYLKGRIFPVEDQLEALKSESQNKiELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    513 QAAKDEAESKLLATEELLHSLRNDYKAQ-EEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINELRaakd 591
Cdd:pfam15921  305 QEQARNQNSMYMRQLSDLESTVSQLRSElREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ---- 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    592 eaeaKLLSTEHSlnaLQAALSAKEEQAASL--EQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARareEL 669
Cdd:pfam15921  381 ----KLLADLHK---REKELSLEKEQNKRLwdRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMER---QM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    670 AAIQSQRElhALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSEsETVAALKGQLEALSQDLA 749
Cdd:pfam15921  451 AAIQGKNE--SLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKE-RAIEATNAEITKLRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    750 TSqaslLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQ 829
Cdd:pfam15921  528 LK----LQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRR 603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    830 AQMQQVQDSHSELEREKRKLESRIESLQQEQVD-SSAQDERTSA----KLEEIQSENTKLAERNCL--LEEQTNHLESQL 902
Cdd:pfam15921  604 LELQEFKILKDKKDAKIRELEARVSDLELEKVKlVNAGSERLRAvkdiKQERDQLLNEVKTSRNELnsLSEDYEVLKRNF 683

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    903 QAKQDEI----GKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRE 978
Cdd:pfam15921  684 RNKSEEMetttNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKE 763

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255    979 ---LKEQDQQLSELRERQREQEQQLKDQAE----RCAKLKAQNSESETQLQATISNLREQLDAYKQTEQ-GIQEKLQAT 1049
Cdd:pfam15921  764 khfLKEEKNKLSQELSTVATEKNKMAGELEvlrsQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQeSVRLKLQHT 842
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
121-554 2.77e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.98  E-value: 2.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   121 QSDLDETSSEFDDSASTARLDVITKDQLYDAYKKSLDRYHKYRCRYTDLAKKyKELERDSSKARSVLVETQDKALRRISE 200
Cdd:PRK02224  250 REELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE-AGLDDADAEAVEARREELEDRDEELRD 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   201 LREQCTLEQQAKAHLEEALRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLES--EQLIDLEESIGKSPLSTN 278
Cdd:PRK02224  329 RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEleEEIEELRERFGDAPVDLG 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   279 GSSGVSDLqrLLKERD---EQLKSVTEKYEAVRKQEEENVLLLAQTK----------QAIHTELELKDTEVRKLQEKLKQ 345
Cdd:PRK02224  409 NAEDFLEE--LREERDelrEREAELEATLRTARERVEEAEALLEAGKcpecgqpvegSPHVETIEEDRERVEELEAELED 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   346 LESQRESHNNEVK--EQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEd 423
Cdd:PRK02224  487 LEEEVEEVEERLEraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE- 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   424 rntQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLrSEQAAKEQQLKHLKEQLGKLKQENE---NYLDKLRENKKSSDS 500
Cdd:PRK02224  566 ---EAEEAREEVAELNSKLAELKERIESLERIRTLL-AAIADAEDEIERLREKREALAELNDerrERLAEKRERKRELEA 641

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 22024255   501 QTNEAQDQQkkLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTL 554
Cdd:PRK02224  642 EFDEARIEE--AREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEEL 693
PTZ00121 PTZ00121
MAEBL; Provisional
 332-1247 5.40e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 5.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   332 KDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKlmatehllntlKESYAIKEQQVVTLEaqlEAIRVENE 411
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDAR-----------KAEEARKAEDARKAE---EARKAEDA 1151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   412 QKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKeqqlkhlkeqlgklKQENENyldKL 491
Cdd:PTZ00121 1152 KRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAAR--------------KAEEER---KA 1214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   492 RENKKSSDSQTNEAQdqQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQ 571
Cdd:PTZ00121 1215 EEARKAEDAKKAEAV--KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   572 REAQSTDSQQKINELRAAKDEAeakllstehslnalQAALSAKEeQAASLEQSLNALKTESEHSLQdlrlhndqlleivq 651
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEA--------------KKADEAKK-KAEEAKKKADAAKKKAEEAKK-------------- 1343

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   652 rhqqndwEAQLARAREELAAiqsqRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQilQDQHANSES 731
Cdd:PTZ00121 1344 -------AAEAAKAEAEAAA----DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE--EDKKKADEL 1410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   732 ETVAALKGQLEALSQdlatsQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEK 811
Cdd:PTZ00121 1411 KKAAAAKKKADEAKK-----KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   812 EELQARVTgileeigtmqaQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLL 891
Cdd:PTZ00121 1486 DEAKKKAE-----------EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   892 EEQTnhlesqlqaKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRV 971
Cdd:PTZ00121 1555 EELK---------KAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL 1625

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   972 KAnlDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLR-EQLDAYKQTEQGIQEKLQATN 1050
Cdd:PTZ00121 1626 KK--AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkAEEDEKKAAEALKKEAEEAKK 1703

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1051 SSYTTQIATLEARwsaansDVERLHEANDALQLEMEQLKIKHGQEREEVKEsiaqknrqvVELQEAMATRDRQLQEKIEA 1130
Cdd:PTZ00121 1704 AEELKKKEAEEKK------KAEELKKAEEENKIKAEEAKKEAEEDKKKAEE---------AKKDEEEKKKIAHLKKEEEK 1768

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1131 -SEKLAKFDEILIENEYLNKHTKQleaelaeSAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKA 1209
Cdd:PTZ00121 1769 kAEEIRKEKEAVIEEELDEEDEKR-------RMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM 1841

                         890       900       910
                  ....*....|....*....|....*....|....*...
gi 22024255  1210 IEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHD 1247
Cdd:PTZ00121 1842 QLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKED 1879
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
355-923 9.31e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 9.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  355 NEVKEQFKKLQATKQEVDAKLMATEHL--LNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTqasdss 432
Cdd:COG4913  228 DALVEHFDDLERAHEALEDAREQIELLepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELR------ 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  433 EQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAK--------EQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNE 504
Cdd:COG4913  302 AELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEE 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  505 AQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLsKENDVNV-EKLHHIneqREAQSTDSQQKI 583
Cdd:COG4913  382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL-ERRKSNIpARLLAL---RDALAEALGLDE 457

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  584 NELRAAkdeAEAKLLSTEHSL--NALQAAL----------SAKEEQAAS------LEQSLNALK-TESEHSLQDLRLHND 644
Cdd:COG4913  458 AELPFV---GELIEVRPEEERwrGAIERVLggfaltllvpPEHYAAALRwvnrlhLRGRLVYERvRTGLPDPERPRLDPD 534

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  645 QLLE--IVQRHQQNDW-EAQLARaREELAAIQSQRELHalELEKSleMERESVAALNSEKASQEEQHRL----------- 710
Cdd:COG4913  535 SLAGklDFKPHPFRAWlEAELGR-RFDYVCVDSPEELR--RHPRA--ITRAGQVKGNGTRHEKDDRRRIrsryvlgfdnr 609

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  711 -KLEQLQREIQILQDQHANSEsETVAALKGQLEALSQDLATSQASLLAKEKELKAsgnklnkikKQHEQHQAKSSDQSAR 789
Cdd:COG4913  610 aKLAALEAELAELEEELAEAE-ERLEALEAELDALQERREALQRLAEYSWDEIDV---------ASAEREIAELEAELER 679

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  790 LEALQSELadrlshsRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQvdSSAQDER 869
Cdd:COG4913  680 LDASSDDL-------AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA--RLELRAL 750

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|....
gi 22024255  870 TSAKLEEIQSENtklaerncLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEH 923
Cdd:COG4913  751 LEERFAAALGDA--------VERELRENLEERIDALRARLNRAEEELERAMRAF 796
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 702-915 1.06e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  702 ASQEEQHRLKLEQLQREIQILQDQhansesetVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQA 781
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKE--------LAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  782 KSSDQSARLEALQSELADRL------------------SHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELE 843
Cdd:COG4942   91 EIAELRAELEAQKEELAELLralyrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22024255  844 REKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAK 915
Cdd:COG4942  171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
530-1108 1.25e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  530 LHSLRNDYKAQEEKVALLEDkLKTLSKENDVNVEKLHHINEQREA-QSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQ 608
Cdd:COG4913  237 LERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  609 AALSAKEEQAASLEQSLNALKTESEHSLQ-DLRLHNDQLLEIVQRHQQndWEAQLARA-------REELAAIQSQrelhA 680
Cdd:COG4913  316 ARLDALREELDELEAQIRGNGGDRLEQLErEIERLERELEERERRRAR--LEALLAALglplpasAEEFAALRAE----A 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  681 LELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQD------------- 747
Cdd:COG4913  390 AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDeaelpfvgeliev 469

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  748 --------------LATSQASLLAKEKELKASGNKLNKIK------------KQHEQHQAKSSDQS--ARLEA------- 792
Cdd:COG4913  470 rpeeerwrgaiervLGGFALTLLVPPEHYAAALRWVNRLHlrgrlvyervrtGLPDPERPRLDPDSlaGKLDFkphpfra 549

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  793 -LQSELADRLSHsRQVESEkEELQARVTGIleeigTMQAQMQQVQDSHsELEREKRKLE---------SRIESLQQEQVD 862
Cdd:COG4913  550 wLEAELGRRFDY-VCVDSP-EELRRHPRAI-----TRAGQVKGNGTRH-EKDDRRRIRSryvlgfdnrAKLAALEAELAE 621

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  863 SSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQL--QAKQDEIGKIQAKLQQVLDEHSKLQNAQELMD---HDH 937
Cdd:COG4913  622 LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDASSDDLAALEEQLEeleAEL 701

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  938 RTLQDKCDAYEKDKLLTKHTldcLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSES 1017
Cdd:COG4913  702 EELEEELDELKGEIGRLEKE---LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDAL 778

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1018 ETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSYT------TQIAT-----LEARWSaansdvERLHEANDAlqlEME 1086
Cdd:COG4913  779 RARLNRAEEELERAMRAFNREWPAETADLDADLESLPeylallDRLEEdglpeYEERFK------ELLNENSIE---FVA 849

                        650       660
                 ....*....|....*....|..
gi 22024255 1087 QLKIKHGQEREEVKESIAQKNR 1108
Cdd:COG4913  850 DLLSKLRRAIREIKERIDPLND 871
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
604-1163 1.55e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 1.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  604 LNALQAALSAKEEQAASLEQsLNALKTESEHSLQDLRlHNDQLLEIVQ----RHQQNDWEAQLARAREELAAIQSQRELH 679
Cdd:COG4913  237 LERAHEALEDAREQIELLEP-IRELAERYAAARERLA-ELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  680 ALELEKSLEMERESVAALNSEKASQeeqhrlkLEQLQREIQILQDQHANSEsETVAALKGQLEALSQDLATSQASLLAKE 759
Cdd:COG4913  315 EARLDALREELDELEAQIRGNGGDR-------LEQLEREIERLERELEERE-RRRARLEALLAALGLPLPASAEEFAALR 386

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  760 KELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSH--SRQVESEKEELQARvTGILEEIGTMQAQMQ---- 833
Cdd:COG4913  387 AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASleRRKSNIPARLLALR-DALAEALGLDEAELPfvge 465

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  834 --QVQDSHSE----LER-----------------------EKRKLESRIESLQQEQVDSSAQDERTSAK--LEEIQSENT 882
Cdd:COG4913  466 liEVRPEEERwrgaIERvlggfaltllvppehyaaalrwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslAGKLDFKPH 545

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  883 KLAER-NCLLEEQTNHL----ESQLQ-------------------AKQDE----------------IGKIQAKLQQVLDE 922
Cdd:COG4913  546 PFRAWlEAELGRRFDYVcvdsPEELRrhpraitragqvkgngtrhEKDDRrrirsryvlgfdnrakLAALEAELAELEEE 625

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  923 HSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDcLQSASEELHRVKANLDR------ELKEQDQQLSELRERQREQ 996
Cdd:COG4913  626 LAEAEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELEAELERldassdDLAALEEQLEELEAELEEL 704

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  997 EQQLKDQAERCAKLKAQNSESETQLQAtisnLREQLDAykqteqgiqeklqATNSSYTTQIATLEARWSAANSDvERLHE 1076
Cdd:COG4913  705 EEELDELKGEIGRLEKELEQAEEELDE----LQDRLEA-------------AEDLARLELRALLEERFAAALGD-AVERE 766

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1077 ANDALQLEMEQLKIKHGQEREEVKESIAQKNRQ----VVELQEAMATRD--RQLQEKIEAS---EKLAKFDEILIENEyl 1147
Cdd:COG4913  767 LRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDADLESLPeyLALLDRLEEDglpEYEERFKELLNENS-- 844

                        650
                 ....*....|....*.
gi 22024255 1148 NKHTKQLEAELAESAE 1163
Cdd:COG4913  845 IEFVADLLSKLRRAIR 860
mukB PRK04863
chromosome partition protein MukB;
432-825 6.41e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.66  E-value: 6.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   432 SEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAkeqqlkhLKEQLGKLKQENENYLDKLrenkkssdSQTNEAQDQQKK 511
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAE-------LNEAESDLEQDYQAASDHL--------NLVQTALRQQEK 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   512 L---QAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLsKENDVNVEKLHHINEQREAQstdSQQKINELRA 588
Cdd:PRK04863  350 IeryQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDEL-KSQLADYQQALDVQQTRAIQ---YQQAVQALER 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   589 AKDEAEAKLLsTEHSLNALQAALSAKEEQAA----SLEQSLN---ALKTESEHSLQDLRLHNDQlleiVQRHQQNDWEAQ 661
Cdd:PRK04863  426 AKQLCGLPDL-TADNAEDWLEEFQAKEQEATeellSLEQKLSvaqAAHSQFEQAYQLVRKIAGE----VSRSEAWDVARE 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   662 LARAREE---LAAIQSQRELHALELEKSLEMERESVAALN--SEKASQEEQHRLKLEQLQREIQILQDqHANSESETVAA 736
Cdd:PRK04863  501 LLRRLREqrhLAEQLQQLRMRLSELEQRLRQQQRAERLLAefCKRLGKNLDDEDELEQLQEELEARLE-SLSESVSEARE 579

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   737 LKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSsdqsarlEALQSELADRLSHSRQVESEKEELQA 816
Cdd:PRK04863  580 RRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDS-------QDVTEYMQQLLERERELTVERDELAA 652


                  ....*....
gi 22024255   817 RVTGILEEI 825
Cdd:PRK04863  653 RKQALDEEI 661
PTZ00121 PTZ00121
MAEBL; Provisional
 165-811 6.93e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 6.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   165 RYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAHLEEALRVEmddmsckmqayqtklqllgenp 244
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD---------------------- 1281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   245 ENITAALERSGQQL-ESEQLIDLEESIGKSPLSTNGSSgvsdlqrlLKERDEQLKsvtEKYEAVRKQEEENvlllAQTKQ 323
Cdd:PTZ00121 1282 ELKKAEEKKKADEAkKAEEKKKADEAKKKAEEAKKADE--------AKKKAEEAK---KKADAAKKKAEEA----KKAAE 1346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   324 AIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMATEhllnTLKESYAIKEQQVVTLEAQL 403
Cdd:PTZ00121 1347 AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKADELKKAAAAKKKADE 1422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   404 EAIRVENEQKVKDLQKQNEDRNT--QASDSSEQLKKLQAAVQDAEsqllskdqllESLRSEQAAKEQQLKHLKEQLGKLK 481
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKadEAKKKAEEAKKAEEAKKKAE----------EAKKADEAKKKAEEAKKADEAKKKA 1492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   482 QENENYLDKLR--ENKKSSDSQTNEAQDQQKKLQAAKDEAESKllaTEELlhslrndYKAQEEKVALLEDKLKTLSKEND 559
Cdd:PTZ00121 1493 EEAKKKADEAKkaAEAKKKADEAKKAEEAKKADEAKKAEEAKK---ADEA-------KKAEEKKKADELKKAEELKKAEE 1562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   560 VNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAalSAKEEQAASLEQslnaLKTESEHSLQDL 639
Cdd:PTZ00121 1563 KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA--KKAEEAKIKAEE----LKKAEEEKKKVE 1636

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   640 RLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESvaalnSEKASQEEQHRLKLEQLQRei 719
Cdd:PTZ00121 1637 QLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA-----AEALKKEAEEAKKAEELKK-- 1709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   720 qilQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELAD 799
Cdd:PTZ00121 1710 ---KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                         650
                  ....*....|..
gi 22024255   800 RLSHSRQVESEK 811
Cdd:PTZ00121 1787 EEDEKRRMEVDK 1798
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
409-847 1.11e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  409 ENEQKVKDLQKQNEDRNT---QASDSSEQLKKLQAAVQDAESQLLSKDQLLE--SLRSEQAAKEQQLKHLKEQLGKLKQE 483
Cdd:COG4717   75 ELEEELKEAEEKEEEYAElqeELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEER 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  484 NENYLDKLRENKKSSdsqtneaQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSkendvnvE 563
Cdd:COG4717  155 LEELRELEEELEELE-------AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ-------E 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  564 KLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALkteseHSLQDLRLHN 643
Cdd:COG4717  221 ELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL-----LALLFLLLAR 295

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  644 DQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEE-QHRLKLEQLQREI-QI 721
Cdd:COG4717  296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEElEEELQLEELEQEIaAL 375

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  722 LQDQHANSESETVAALK--GQLEALSQDLATSQASLLAKEKELKASGNKLNK--IKKQHEQHQAKSSDQSARLEALQSEL 797
Cdd:COG4717  376 LAEAGVEDEEELRAALEqaEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELEELEEELEELEEELEELREEL 455

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255  798 ADRLSHSRQVES---------EKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKR 847
Cdd:COG4717  456 AELEAELEQLEEdgelaellqELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 284-633 2.42e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 2.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    284 SDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHTelelKDTEVRKLQEKLKQLESQRESH-NNEVKEQFK 362
Cdd:TIGR04523  242 NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE----LEKQLNQLKSEISDLNNQKEQDwNKELKSELK 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    363 KLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQK---VKDLQKQNEDRNTQASDSSEQLKKLQ 439
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKqneIEKLKKENQSYKQEIKNLESQINDLE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    440 AAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDE- 518
Cdd:TIGR04523  398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSi 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    519 --AESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKEND---VNVEKLHHINEQREAQSTDSQQKINE-------- 585
Cdd:TIGR04523  478 nkIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISslkEKIEKLESEKKEKESKISDLEDELNKddfelkke 557

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 22024255    586 -LRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESE 633
Cdd:TIGR04523  558 nLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE 606
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 315-557 2.57e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 2.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  315 VLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQReshnNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQ 394
Cdd:COG4942    8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  395 QVVTLEAQLEAIRVENEQKVKDLQKQNedRNTQASDSSEQLKKLQAavQDAESQLLSKDQLLESLRSEQAAKEQQLKHLK 474
Cdd:COG4942   84 ELAELEKEIAELRAELEAQKEELAELL--RALYRLGRQPPLALLLS--PEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  475 EQLGKLKQEnenyldkLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTL 554
Cdd:COG4942  160 AELAALRAE-------LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232


                 ...
gi 22024255  555 SKE 557
Cdd:COG4942  233 EAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 319-528 2.73e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 2.73e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  319 AQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAklmaTEHLLNTLKESYAIKEQQVVT 398
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA----LEQELAALEAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  399 LEAQLEAIRVENEQKVKDLQKQNE----------DRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQ 468
Cdd:COG4942   95 LRAELEAQKEELAELLRALYRLGRqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22024255  469 QLKHL-------KEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEE 528
Cdd:COG4942  175 ELEALlaeleeeRAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 411-986 3.10e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 3.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    411 EQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQEnenyLDK 490
Cdd:TIGR04523   53 EKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVE----LNK 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    491 LRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINE 570
Cdd:TIGR04523  129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKK 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    571 QREAQSTdSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIv 650
Cdd:TIGR04523  209 KIQKNKS-LESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKEL- 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    651 qrhqqndwEAQLARAREELAAIQSQRELHALELEKSlemeresvaalnsekasqeeqhrlKLEQLQREIQILQDQHANSE 730
Cdd:TIGR04523  287 --------EKQLNQLKSEISDLNNQKEQDWNKELKS------------------------ELKNQEKKLEEIQNQISQNN 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    731 sETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQ---- 806
Cdd:TIGR04523  335 -KIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQkdeq 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    807 ---VESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTK 883
Cdd:TIGR04523  414 ikkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    884 LAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVldEHSKLQNAQELMDHDHRTLQDKcdaYEKDKLLTKHTLDCLQS 963
Cdd:TIGR04523  494 KEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL--ESEKKEKESKISDLEDELNKDD---FELKKENLEKEIDEKNK 568

                          570       580
                   ....*....|....*....|...
gi 22024255    964 ASEELHRVKANLDRELKEQDQQL 986
Cdd:TIGR04523  569 EIEELKQTQKSLKKKQEEKQELI 591
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 196-799 3.73e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 55.23  E-value: 3.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    196 RRISELREQCtleQQAKAHLEEALRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESIGKSPL 275
Cdd:pfam12128  272 TLIASRQEER---QETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQ 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    276 STNGSSGVSDLQRLLKERDEQLKSVTEKYEAVR-KQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQ-RESH 353
Cdd:pfam12128  349 LPSWQSELENLEERLKALTGKHQDVTAKYNRRRsKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElREQL 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    354 N------NEVKEQFK-KLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNT 426
Cdd:pfam12128  429 EagklefNEEEYRLKsRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEAL 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    427 QasDSSEQLKKLQAAVQDAESQLLSKD-QLLESLRSEQAAKEQQLKHL--KEQLGKLKQENENYLDKLRENKKSSDSQTN 503
Cdd:pfam12128  509 R--QASRRLEERQSALDELELQLFPQAgTLLHFLRKEAPDWEQSIGKVisPELLHRTDLDPEVWDGSVGGELNLYGVKLD 586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    504 EAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEqreaqstDSQQKI 583
Cdd:pfam12128  587 LKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARL-------DLRRLF 659

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    584 NELRAAKDEAEakllstehslNALQAALSAKEEQAASLEQSLNALKTE----SEHSLQDLRLHNDQLLEIVQRhQQNDWE 659
Cdd:pfam12128  660 DEKQSEKDKKN----------KALAERKDSANERLNSLEAQLKQLDKKhqawLEEQKEQKREARTEKQAYWQV-VEGALD 728

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    660 AQLARAREELAAIQSQRELHALELE-------KSLEMERESVAALNSE------KASQEEQHRLKLEQLQREIQILQDQH 726
Cdd:pfam12128  729 AQLALLKAAIAARRSGAKAELKALEtwykrdlASLGVDPDVIAKLKREirtlerKIERIAVRRQEVLRYFDWYQETWLQR 808

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22024255    727 ANSESETVAALKGQLEALSQDLAtsqasllAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELAD 799
Cdd:pfam12128  809 RPRLATQLSNIERAISELQQQLA-------RLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 657-1345 4.46e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.69  E-value: 4.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    657 DWEAQLARAREELAAI-QSQRELHALELEKSLEMEResvaaLNSEKASQEEQHRLKLEQLQREIQILQDQHANSESEtVA 735
Cdd:TIGR02169  167 EFDRKKEKALEELEEVeENIERLDLIIDEKRQQLER-----LRREREKAERYQALLKEKREYEGYELLKEKEALERQ-KE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    736 ALKGQLEALSQDLATSQASLLAKEKELKA---------------SGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADR 800
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEieqlleelnkkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    801 LSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQ-------QEQVDSSAQDERTSAK 873
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefaetrDELKDYREKLEKLKRE 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    874 LEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQnaQELMdhdhrTLQDKCDAYEKDKLL 953
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE--WKLE-----QLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    954 TKHTLDCLQsasEELHRVKANLDReLKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATI-SNLREQL 1032
Cdd:TIGR02169  474 LKEEYDRVE---KELSKLQRELAE-AEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIeVAAGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1033 DAYKQTEQGIQEK----LQATNSSYTTQIATLEARwsAANSDVERLHE------ANDALQLEMEQLKIKHGQEREE-VKE 1101
Cdd:TIGR02169  550 NNVVVEDDAVAKEaielLKRRKAGRATFLPLNKMR--DERRDLSILSEdgvigfAVDLVEFDPKYEPAFKYVFGDTlVVE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1102 SIAQKNRQVVELQeaMATRDRQLQEK------------IEASEKLAKFDEILIENEYLNKHTKQLEAELAESAELKEKLK 1169
Cdd:TIGR02169  628 DIEAARRLMGKYR--MVTLEGELFEKsgamtggsraprGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1170 SLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQ 1249
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1250 IELAMSRDEQalLQAEADGLRQEVICLKEHL--------SPSTDSDSLRSLNERLQRELEDLKHKSAG---AESNMQQEI 1318
Cdd:TIGR02169  786 ARLSHSRIPE--IQAELSKLEEEVSRIEARLreieqklnRLTLEKEYLEKEIQELQEQRIDLKEQIKSiekEIENLNGKK 863

                          730       740
                   ....*....|....*....|....*..
gi 22024255   1319 EELQANNQQMAERINELETLRAGIQAQ 1345
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKE 890
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 651-876 5.55e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 5.55e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  651 QRHQQNDWEAQLARAREELAAIQSQRELHALElEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQhansE 730
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE----I 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  731 SETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESE 810
Cdd:COG4942   93 AELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255  811 KEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEE 876
Cdd:COG4942  173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 1433-1472 6.28e-07

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 47.35  E-value: 6.28e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 22024255   1433 NTEFEYLRNIMFQYLTGNTNNE--TLVKVISAVLKFSPQQAQ 1472
Cdd:pfam01465    1 GANLEYLKNVLLQFLESKESSErkQLLPVIATLLKFSPEEEQ 42
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
681-1172 1.41e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   681 LELEKSLEMERESVAALNSEKASQEEQ--------HRLKLEQLQREIQilqdqHANSESETVAALKGQLEALSQDLATSQ 752
Cdd:PRK02224  176 LGVERVLSDQRGSLDQLKAQIEEKEEKdlherlngLESELAELDEEIE-----RYEEQREQARETRDEADEVLEEHEERR 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   753 ASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHS-------RQVESEKEELQARVTGILEEI 825
Cdd:PRK02224  251 EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELRDRL 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   826 GTMQAQMQQVQDSHSELEREKRKLESRIESLQQE--QVDSSAQDERT-----SAKLEEIQSENTKLAERNCLLEEQTNHL 898
Cdd:PRK02224  331 EECRVAAQAHNEEAESLREDADDLEERAEELREEaaELESELEEAREavedrREEIEELEEEIEELRERFGDAPVDLGNA 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   899 ESQLQAKQDEIGKIQAKLQQVLDEHSKLQN----AQELMD--------HDHRTLQDKCDAYEKDKLLTKHTLDcLQSASE 966
Cdd:PRK02224  411 EDFLEELREERDELREREAELEATLRTARErveeAEALLEagkcpecgQPVEGSPHVETIEEDRERVEELEAE-LEDLEE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   967 ELHRVKANLDR--ELKEQDQQLSELRERQREQEQQLKDQ-------AERCAKLKAQNSESETQLQ---ATISNLREQLDA 1034
Cdd:PRK02224  490 EVEEVEERLERaeDLVEAEDRIERLEERREDLEELIAERretieekRERAEELRERAAELEAEAEekrEAAAEAEEEAEE 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1035 YKQTEQGIQEKLQATNSSYTT--QIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVE 1112
Cdd:PRK02224  570 AREEVAELNSKLAELKERIESleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIE 649

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1113 lqEAMATRDRQLQEKIEASEKLAKFDEiliENEYLNKHTKQLEAELAESAELKEKLKSLQ 1172
Cdd:PRK02224  650 --EAREDKERAEEYLEQVEEKLDELRE---ERDDLQAEIGAVENELEELEELRERREALE 704
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 217-987 1.65e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 1.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    217 EALRVEMDDMSCKMQAYQTKLQLLGENPENitaALERSGQQLESEQLIDLEESIGKSplstngssgvsdLQRLLKERDEQ 296
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEK---ACEIRDQITSKEAQLESSREIVKS------------YENELDPLKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    297 LKSVTEKYEAVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDaKLM 376
Cdd:TIGR00606  254 LKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELE-KLN 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    377 ATEHLLNTLKESYAIKEQQVvtleaQLEAIRVENEQKVKDLQKQNE------DRNTQASDSSEQLKKLQAAVQDA-ESQL 449
Cdd:TIGR00606  333 KERRLLNQEKTELLVEQGRL-----QLQADRHQEHIRARDSLIQSLatrlelDGFERGPFSERQIKNFHTLVIERqEDEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    450 LSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLrenkkssDSQTNEAQDQQKKLQAAKDEAESKLLATEEL 529
Cdd:TIGR00606  408 KTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEIL-------EKKQEELKFVIKELQQLEGSSDRILELDQEL 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    530 LHSLRNDYKAQE---------EKVALLEDKL---KTLSKENDVNVEKLHHIN--EQREAQSTDSQQKINELRAAKDEAEA 595
Cdd:TIGR00606  481 RKAERELSKAEKnsltetlkkEVKSLQNEKAdldRKLRKLDQEMEQLNHHTTtrTQMEMLTKDKMDKDEQIRKIKSRHSD 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    596 KLLST----------EHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLL----EIVQRHQQNDWEAQ 661
Cdd:TIGR00606  561 ELTSLlgyfpnkkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSsyedKLFDVCGSQDEESD 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    662 LARAREELAAIQSQRELHAL------ELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESEtVA 735
Cdd:TIGR00606  641 LERLKEEIEKSSKQRAMLAGatavysQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESE-LK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    736 ALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSEL---ADRLSHSRQVESEKE 812
Cdd:TIGR00606  720 KKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEesaKVCLTDVTIMERFQM 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    813 ELQARVTGILEEIGTMQA-----QMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAE- 886
Cdd:TIGR00606  800 ELKDVERKIAQQAAKLQGsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTn 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    887 --RNCLLEEQTNHLESQLQAKQDEIGkiQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSA 964
Cdd:TIGR00606  880 lqRRQQFEEQLVELSTEVQSLIREIK--DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYM 957

                          810       820
                   ....*....|....*....|...
gi 22024255    965 SEELHRVKANLDRELKEQDQQLS 987
Cdd:TIGR00606  958 KDIENKIQDGKDDYLKQKETELN 980
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 570-789 1.90e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 1.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  570 EQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEI 649
Cdd:COG4942   30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  650 V---QRHQQNDWEAQLARAREELAAIQSQRELHAL-----ELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQI 721
Cdd:COG4942  110 LralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLaparrEQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255  722 LQDQHANSEsETVAALKGQLEALSQDLATsqasLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSAR 789
Cdd:COG4942  190 LEALKAERQ-KLLARLEKELAELAAELAE----LQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
mukB PRK04863
chromosome partition protein MukB;
503-887 1.94e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 52.65  E-value: 1.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   503 NEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKendvnveklhHINEQREAqsTDSQQK 582
Cdd:PRK04863  282 RVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASD----------HLNLVQTA--LRQQEK 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   583 INELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTesehslqdlrlhndQLLEIVQRhqqndWEAQL 662
Cdd:PRK04863  350 IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKS--------------QLADYQQA-----LDVQQ 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   663 ARAreelaaIQSQRELHALELEKSL----EMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDqhANSESETVAALk 738
Cdd:PRK04863  411 TRA------IQYQQAVQALERAKQLcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQA--AHSQFEQAYQL- 481

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   739 gqLEALSQDLATSQASLLAKEKElkasgnklnkikKQHEQHQAkssdQSARLEALQSELADRLSHSRQvesekeelQARV 818
Cdd:PRK04863  482 --VRKIAGEVSRSEAWDVARELL------------RRLREQRH----LAEQLQQLRMRLSELEQRLRQ--------QQRA 535

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255   819 TGILEEIGTMQAQMQQVQDshsELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAER 887
Cdd:PRK04863  536 ERLLAEFCKRLGKNLDDED---ELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAAR 601
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
288-818 2.27e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 2.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   288 RLLKERDEQLKSVTEKYEAVRKQEEEnvllLAQTKQAIHT---ELELKDTEVRKLQEKLKQLESQREshnnEVKEQFKKL 364
Cdd:PRK03918  207 REINEISSELPELREELEKLEKEVKE----LEELKEEIEElekELESLEGSKRKLEEKIRELEERIE----ELKKEIEEL 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   365 QATKQEVDA-KLMATEHL-LNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAV 442
Cdd:PRK03918  279 EEKVKELKElKEKAEEYIkLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   443 QDAE--SQLLSKDQLLESLRSEQAAKE-QQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDE- 518
Cdd:PRK03918  359 ERHElyEEAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKc 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   519 ----AESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLsKENDVNVEKLhhINEQReaqstdsqqkinELRAAKDEAE 594
Cdd:PRK03918  439 pvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKL-RKELRELEKV--LKKES------------ELIKLKELAE 503

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   595 aKLLSTEHSLNALQA-ALSAKEEQAASLEQSLNALKTESEHSLQDLRlhndqlleivqrhQQNDWEAQLARAREELAAIQ 673
Cdd:PRK03918  504 -QLKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-------------KLEELKKKLAELEKKLDELE 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   674 SQRElhalELEKSLEMER-ESVAALNSEKASQEEQHR--LKLEQLQREIQILQDQHANSESEtvaalkgqLEALSQDLAT 750
Cdd:PRK03918  570 EELA----ELLKELEELGfESVEELEERLKELEPFYNeyLELKDAEKELEREEKELKKLEEE--------LDKAFEELAE 637

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255   751 SQASLLAKEKELKASGNKLNkiKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARV 818
Cdd:PRK03918  638 TEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 570-1273 2.76e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 2.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    570 EQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALsakeEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEI 649
Cdd:TIGR00618  211 PCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQ----EEQLKKQQLLKQLRARIEELRAQEAVLEETQERI 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    650 VQRHQQndweAQLARAREELAAIQSQRELHALEL---EKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQdqh 726
Cdd:TIGR00618  287 NRARKA----APLAAHIKAVTQIEQQAQRIHTELqskMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD--- 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    727 ANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIkkQHEQHQAKSSDQSARleALQSELAdrlshsrq 806
Cdd:TIGR00618  360 AHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL--QREQATIDTRTSAFR--DLQGQLA-------- 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    807 VESEKEELQARVTGILEEIGTMQAQMQQVQDSHseLEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQsentKLAE 886
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIH--LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLL----ELQE 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    887 RNCLLEEQTNHLESQLQAkQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLD----CLQ 962
Cdd:TIGR00618  502 EPCPLCGSCIHPNPARQD-IDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSiltqCDN 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    963 SASEELHRVKANLDRELKEQDQQLSELRerqreqeqqlkdqaercaKLKAQNSESETQLQATISNLREQLDAYKQTEQGI 1042
Cdd:TIGR00618  581 RSKEDIPNLQNITVRLQDLTEKLSEAED------------------MLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1043 QEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKikhgQEREEVKESIAQKNRQVVELQEAMATRDR 1122
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEK----EQLTYWKEMLAQCQTLLRELETHIEEYDR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1123 QLQEKIEASE----KLAKFDEILieNEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSAT 1198
Cdd:TIGR00618  719 EFNEIENASSslgsDLAAREDAL--NQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREE 796

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255   1199 ATAEVSELKKAIEEQA----VELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEV 1273
Cdd:TIGR00618  797 DTHLLKTLEAEIGQEIpsdeDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 403-825 3.08e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.26  E-value: 3.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  403 LEAIRVEneQKVKDLQKQ--NEDRNTQASD----------SSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQL 470
Cdd:COG3096  245 LEAIRVT--QSDRDLFKHliTEATNYVAADymrhanerreLSERALELRRELFGARRQLAEEQYRLVEMARELEELSARE 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  471 KHLKEQLgklkQENENYLDKLRenkkssdsqtnEAQDQQKKL---QAAKDEAESKLLATEELLHSLRNDYKAQEEKVALL 547
Cdd:COG3096  323 SDLEQDY----QAASDHLNLVQ-----------TALRQQEKIeryQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAA 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  548 EDKLKTLSKEndvnvekLHHINEQREAQSTDS---QQKINELRAAKDEAEAKLLSTEhSLNALQAALSAKEEQAAS---- 620
Cdd:COG3096  388 EEEVDSLKSQ-------LADYQQALDVQQTRAiqyQQAVQALEKARALCGLPDLTPE-NAEDYLAAFRAKEQQATEevle 459

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  621 LEQSLN---ALKTESEHSLQDLRLHNDQlleiVQRHQQndWEA---QLARAREE--LAAIQSQRELHALELEKSLEMERE 692
Cdd:COG3096  460 LEQKLSvadAARRQFEKAYELVCKIAGE----VERSQA--WQTareLLRRYRSQqaLAQRLQQLRAQLAELEQRLRQQQN 533

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  693 SVAALN--SEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALkGQLEALSQDLATSQASLLAKEKELKASGNKLN 770
Cdd:COG3096  534 AERLLEefCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR-SELRQQLEQLRARIKELAARAPAWLAAQDALE 612

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 22024255  771 KIKKQHEQHQAKSSDQSARLEALqseladrLSHSRQVESEKEELQARVTGILEEI 825
Cdd:COG3096  613 RLREQSGEALADSQEVTAAMQQL-------LEREREATVERDELAARKQALESQI 660
PRK11281 PRK11281
mechanosensitive channel MscK;
693-982 3.87e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   693 SVAALNSEKaSQEEQHRLKLEQLQREIQILqDQHANSESETvAALKGQLEALSQDLATSQASLLA-KEKELKASGNKLNK 771
Cdd:PRK11281   44 QLDALNKQK-LLEAEDKLVQQDLEQTLALL-DKIDRQKEET-EQLKQQLAQAPAKLRQAQAELEAlKDDNDEETRETLST 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   772 IK-KQHEQHQAKSSDQsarLEALQSELADRLSHSRQVESEKEELQArvtgileEIGTMQAQMQQV-QDSHSELEREKRKL 849
Cdd:PRK11281  121 LSlRQLESRLAQTLDQ---LQNAQNDLAEYNSQLVSLQTQPERAQA-------ALYANSQRLQQIrNLLKGGKVGGKALR 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   850 ESRIESLQQEQVDSSAQDERTSAKLEEiqseNTKL-----AERNcLLEEQTNHLESQLQAKQDEIG-------KIQAKLQ 917
Cdd:PRK11281  191 PSQRVLLQAEQALLNAQNDLQRKSLEG----NTQLqdllqKQRD-YLTARIQRLEHQLQLLQEAINskrltlsEKTVQEA 265

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22024255   918 QVLDEHSKLQN----AQELmDHDHRTLQDKCDAYEK------DKLLTKHTLDCLQSAseelhrvkanlDRELKEQ 982
Cdd:PRK11281  266 QSQDEAARIQAnplvAQEL-EINLQLSQRLLKATEKlntltqQNLRVKNWLDRLTQS-----------ERNIKEQ 328
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 836-1052 6.12e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 6.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  836 QDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAK 915
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  916 LQQVLDEHSK-LQNAQELMDHDHRTL----QDKCDAYEKDKLLT------KHTLDCLQSASEELHRVKANLDRELKEQDQ 984
Cdd:COG4942   99 LEAQKEELAElLRALYRLGRQPPLALllspEDFLDAVRRLQYLKylaparREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255  985 QLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNSS 1052
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
336-764 7.08e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 7.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  336 VRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKlmatEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKvk 415
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELEKL-- 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  416 DLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENK 495
Cdd:COG4717  122 EKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  496 KSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVAL---------------LEDKLKTLSKENDV 560
Cdd:COG4717  202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLliaaallallglggsLLSLILTIAGVLFL 281

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  561 NVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKT--------ES 632
Cdd:COG4717  282 VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEllreaeelEE 361

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  633 EHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHAlelekslEMERESVAALNSEKASQEEQHRLKL 712
Cdd:COG4717  362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEE-------QLEELLGELEELLEALDEEELEEEL 434

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|..
gi 22024255  713 EQLQREIQILQDQHaNSESETVAALKGQLEALSQDLATSQasLLAKEKELKA 764
Cdd:COG4717  435 EELEEELEELEEEL-EELREELAELEAELEQLEEDGELAE--LLQELEELKA 483
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 585-921 8.14e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.72  E-value: 8.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  585 ELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNAlktESEHsLQdLRLHNDQLLEIVQRHQQN--DWEAQL 662
Cdd:COG3096  289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQA---ASDH-LN-LVQTALRQQEKIERYQEDleELTERL 363

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  663 ARAREELAAIQSQRElhalELEKSLEMERESVAALNSE-------------KASQEEQHRLKLEQLQREIQiLQDQHANS 729
Cdd:COG3096  364 EEQEEVVEEAAEQLA----EAEARLEAAEEEVDSLKSQladyqqaldvqqtRAIQYQQAVQALEKARALCG-LPDLTPEN 438

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  730 ESETVAALKGQLEA-------LSQDLATSQAS------------LLAKEKELKASGNKLNKIKKQHEQHQAkssdQSARL 790
Cdd:COG3096  439 AEDYLAAFRAKEQQateevleLEQKLSVADAArrqfekayelvcKIAGEVERSQAWQTARELLRRYRSQQA----LAQRL 514

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  791 EALQSELADRlshsrqveSEKEELQARVTGILEEIGtmQAQMQQVQDSHsELEREKRKLESRIESLQQEQVDSSAQDERT 870
Cdd:COG3096  515 QQLRAQLAEL--------EQRLRQQQNAERLLEEFC--QRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVEQRSEL 583

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 22024255  871 SAKLEEIQSENTKLAERNCL---LEEQTNHLESQLQAKQDEIGKIQAKLQQVLD 921
Cdd:COG3096  584 RQQLEQLRARIKELAARAPAwlaAQDALERLREQSGEALADSQEVTAAMQQLLE 637
PTZ00121 PTZ00121
MAEBL; Provisional
 490-1251 8.22e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 8.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   490 KLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSK-ENDVNVEKLHHI 568
Cdd:PTZ00121 1099 KAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKKA 1178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   569 NEQREAQSTdsqQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLE 648
Cdd:PTZ00121 1179 EAARKAEEV---RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIR 1255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   649 IVQrhqqndwEAQLARAREELAAIQSQRELHALELEKSLEMEResvaalnSEKASQEEQHRlKLEQLQREIQilQDQHAN 728
Cdd:PTZ00121 1256 KFE-------EARMAHFARRQAAIKAEEARKADELKKAEEKKK-------ADEAKKAEEKK-KADEAKKKAE--EAKKAD 1318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   729 SESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSElADRLSHSRQVE 808
Cdd:PTZ00121 1319 EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-AEEKKKADEAK 1397

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   809 SEKEELQARVtgilEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQsentKLAERN 888
Cdd:PTZ00121 1398 KKAEEDKKKA----DELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK----KKAEEA 1469

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   889 CLLEEQTNHLESQLQAkqDEIGKIQAKLQQVLDEHSKLQNAQELMDhDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEEL 968
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKA--DEAKKKAEEAKKKADEAKKAAEAKKKAD-EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   969 HRVKANLDRELKeqdqqlselrerqreqeqqlkdQAERCAKLKAQNSESETQLQAtisnLREQLDAYKQTEQGIQEKLQA 1048
Cdd:PTZ00121 1547 KADELKKAEELK----------------------KAEEKKKAEEAKKAEEDKNMA----LRKAEEAKKAEEARIEEVMKL 1600

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1049 TNSsyttqiatlearwsaansdvERLHEANDALQLEMEQLKIKHGQEREEVKESIAQ-KNRQVVELQEAMATRDRQLQEK 1127
Cdd:PTZ00121 1601 YEE--------------------EKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1128 IEASEKLAKFDEilieneylnkhtKQLEAELAESAELKEKLKSLQCElyvlQEKAEQHAVQMAEKETQSATATAEvsELK 1207
Cdd:PTZ00121 1661 IKAAEEAKKAEE------------DKKKAEEAKKAEEDEKKAAEALK----KEAEEAKKAEELKKKEAEEKKKAE--ELK 1722

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....
gi 22024255  1208 KAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIE 1251
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
821-1357 8.80e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 8.80e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  821 ILEEIGTMQAQMQQVQDSHSELEREKRKLE--SRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERncLLEEQTNHL 898
Cdd:COG4913  223 TFEAADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLE--LLEAELEEL 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  899 ESQLQAKQDEIGKIQAKLQQVLDEHSKLQnaQELMDHDHRTLQDkcdayekdkllTKHTLDCLQSASEELHRVKANLDRE 978
Cdd:COG4913  301 RAELARLEAELERLEARLDALREELDELE--AQIRGNGGDRLEQ-----------LEREIERLERELEERERRRARLEAL 367

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  979 LKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDaykQTEQGIQEkLQATNSSYTTQIA 1058
Cdd:COG4913  368 LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR---ELEAEIAS-LERRKSNIPARLL 443

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1059 TLEARW-SAANSDVERLHEANDALQLEMEQL-------KIKHGQER---------EEVKESI-AQKNRQVVELQEAMATR 1120
Cdd:COG4913  444 ALRDALaEALGLDEAELPFVGELIEVRPEEErwrgaieRVLGGFALtllvppehyAAALRWVnRLHLRGRLVYERVRTGL 523

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1121 DRQLQEKIEA---SEKLA----------------KFDEILIEN-EYLNKHTKQLEAE--LAESAELKEK-LKSLQCELYV 1177
Cdd:COG4913  524 PDPERPRLDPdslAGKLDfkphpfrawleaelgrRFDYVCVDSpEELRRHPRAITRAgqVKGNGTRHEKdDRRRIRSRYV 603

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1178 LQEKAEQhavQMAEKETQSATATAEVSELKKAIEEQAVE---LTRQKEHASFVTEQSDAvQKDLLQAQQQLHDKQIELAM 1254
Cdd:COG4913  604 LGFDNRA---KLAALEAELAELEEELAEAEERLEALEAEldaLQERREALQRLAEYSWD-EIDVASAEREIAELEAELER 679

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1255 ---SRDEQALLQAEADGLRQEViclkehlspstdsdslrslnERLQRELEDLKHKSAGAES---NMQQEIEELQANNQQM 1328
Cdd:COG4913  680 ldaSSDDLAALEEQLEELEAEL--------------------EELEEELDELKGEIGRLEKeleQAEEELDELQDRLEAA 739

                        570       580
                 ....*....|....*....|....*....
gi 22024255 1329 AERINELETLRAGIQAQQLLASMAPKNVQ 1357
Cdd:COG4913  740 EDLARLELRALLEERFAAALGDAVERELR 768
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 733-931 9.06e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 9.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  733 TVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKE 812
Cdd:COG4942   14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  813 ELQARVTGILEEIGTMQAQMQQV-----------QDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSEN 881
Cdd:COG4942   94 ELRAELEAQKEELAELLRALYRLgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 22024255  882 TKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQE 931
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
PRK11281 PRK11281
mechanosensitive channel MscK;
355-637 1.05e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 50.30  E-value: 1.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   355 NEVKEQFKKLQATKQEVDAKLMATEHLLNTLkesyaikeqqvvtleAQLEAIRvENEQKVKDLQKQNEDRNTQASDSSEQ 434
Cdd:PRK11281   39 ADVQAQLDALNKQKLLEAEDKLVQQDLEQTL---------------ALLDKID-RQKEETEQLKQQLAQAPAKLRQAQAE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   435 LKKLQAAVQDAESQLLSKdQLLESLRSEQAAKEQQLKHLKEQLGklkqenenyldklrenkkSSDSQTNEAQDQQKKLQA 514
Cdd:PRK11281  103 LEALKDDNDEETRETLST-LSLRQLESRLAQTLDQLQNAQNDLA------------------EYNSQLVSLQTQPERAQA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   515 AKDEAESKLLATEELLHSLRNDYKA-QEEKVALLEDKLKTLSKENDVNveklhhineQREAQSTDSQQKINELRaaKDEA 593
Cdd:PRK11281  164 ALYANSQRLQQIRNLLKGGKVGGKAlRPSQRVLLQAEQALLNAQNDLQ---------RKSLEGNTQLQDLLQKQ--RDYL 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 22024255   594 EAKLLSTEHSLNALQAALSAK-----EEQAASLEQSLNA--------LKTESEHSLQ 637
Cdd:PRK11281  233 TARIQRLEHQLQLLQEAINSKrltlsEKTVQEAQSQDEAariqanplVAQELEINLQ 289
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
283-400 1.24e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 1.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  283 VSDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLllaqtkqaihtelelKDTEVRKLQEKLKQLESQRESHNNEVKEQFK 362
Cdd:COG2433  429 VEELEAELEEKDERIERLERELSEARSEERREIR---------------KDREISRLDREIERLERELEEERERIEELKR 493

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 22024255  363 KLQATKQ----EVDAKLMA-------TEHLLNTLKESYAIKEQQVVTLE 400
Cdd:COG2433  494 KLERLKElwklEHSGELVPvkvvekfTKEAIRRLEEEYGLKEGDVVYLR 542
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 493-741 1.25e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  493 ENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQR 572
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  573 EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTEsehsLQDLRLHNDQLLEivQR 652
Cdd:COG4942  100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALRAELEA--ER 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  653 HQQNDWEAQLARAREELAAIQSQRElhalELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIqilQDQHANSESE 732
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQ----KLLARLEKELAELAAELAELQQEAEELEALIARLEAEA---AAAAERTPAA 246


                 ....*....
gi 22024255  733 TVAALKGQL 741
Cdd:COG4942  247 GFAALKGKL 255
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
843-1345 1.36e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.04  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   843 EREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERnclLEEQTNHLEsQLQAKQDEIGKIQAKLQQVLDE 922
Cdd:PRK02224  198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV---LEEHEERRE-ELETLEAEIEDLRETIAETERE 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   923 HSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKD 1002
Cdd:PRK02224  274 REELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADD 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1003 QAERCAKLKAQNSESETQLQATISNLREQldaykqteqgiQEKLQATNSsyttQIATLEARWSAANSDVERLHEANDALQ 1082
Cdd:PRK02224  354 LEERAEELREEAAELESELEEAREAVEDR-----------REEIEELEE----EIEELRERFGDAPVDLGNAEDFLEELR 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1083 lemeqlkikhgQEREEVKESIAQKNRQVVELQEAMATRDRQLQE--------KIEASEKLAKFDEILIENEYLNKHTKQL 1154
Cdd:PRK02224  419 -----------EERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqPVEGSPHVETIEEDRERVEELEAELEDL 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1155 E---AELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQS 1231
Cdd:PRK02224  488 EeevEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1232 DAVQ---KDLLQAQQQLHDKQIELAMSRDeqalLQAEADGLRQEVICLKEHLSPSTD-----SDSLRSLNERlQRELEDL 1303
Cdd:PRK02224  568 EEAReevAELNSKLAELKERIESLERIRT----LLAAIADAEDEIERLREKREALAElnderRERLAEKRER-KRELEAE 642

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 22024255  1304 KHKSAGAESnmQQEIEELQANNQQMAERINELETLRAGIQAQ 1345
Cdd:PRK02224  643 FDEARIEEA--REDKERAEEYLEQVEEKLDELREERDDLQAE 682
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 351-552 1.84e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.67  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  351 ESHNNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASD 430
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  431 SSEQLKKLQ--AAVQDAES--QLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQ 506
Cdd:COG3883   95 LYRSGGSVSylDVLLGSESfsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 22024255  507 DQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLK 552
Cdd:COG3883  175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
285-723 1.90e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 1.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  285 DLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAIHtELELKDTEVRKLQEKLKQLESQRESHnnEVKEQFKKL 364
Cdd:COG4717   54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQE-ELEELEEELEELEAELEELREELEKL--EKLLQLLPL 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  365 QATKQEVDAKLMATEHLLNTLKEsyaiKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASdssEQLKKLQAAVQD 444
Cdd:COG4717  131 YQELEALEAELAELPERLEELEE----RLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  445 AESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDK-----------LRENKKSSDSQTNEAQDQQKKLQ 513
Cdd:COG4717  204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlllliaaallaLLGLGGSLLSLILTIAGVLFLVL 283

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  514 AAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINELRAAkdEA 593
Cdd:COG4717  284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL--EE 361

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  594 EAKLLSTEHSLNALQAALSAKEE----QAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREEL 669
Cdd:COG4717  362 ELQLEELEQEIAALLAEAGVEDEeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 22024255  670 AAIQSQRELHALEL-EKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQ 723
Cdd:COG4717  442 EELEEELEELREELaELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALK 496
mukB PRK04863
chromosome partition protein MukB;
284-709 2.09e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.57  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   284 SDLQRLLKERDEQLKSVTEKYEAVRKQeeenVLLLAQTKQAIHT-ELELKDTEVRKLQEKLKQLESQREShnneVKEQFK 362
Cdd:PRK04863  847 VELERALADHESQEQQQRSQLEQAKEG----LSALNRLLPRLNLlADETLADRVEEIREQLDEAEEAKRF----VQQHGN 918

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   363 KLQATKQEVdAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLK-KLQAA 441
Cdd:PRK04863  919 ALAQLEPIV-SVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRqRLEQA 997

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   442 VQD----------AESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKL----KQENENYL----DKLRENKKSSDSQTN 503
Cdd:PRK04863  998 EQErtrareqlrqAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpaDSGAEERArarrDELHARLSANRSRRN 1077

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   504 EAQDQQKKLQAAKDEAESKLLATEEllhslrnDYKAQEEKVALLE---DKLKTLSKENDVNvEKLHhineQREaqstDSQ 580
Cdd:PRK04863 1078 QLEKQLTFCEAEMDNLTKKLRKLER-------DYHEMREQVVNAKagwCAVLRLVKDNGVE-RRLH----RRE----LAY 1141

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   581 QKINELRAAKDEAeakllstehsLNALQAALSAKEEQAASLEQSLNALKTESEHSL-----QDLR-------LHNDQLLE 648
Cdd:PRK04863 1142 LSADELRSMSDKA----------LGALRLAVADNEHLRDVLRLSEDPKRPERKVQFyiavyQHLRerirqdiIRTDDPVE 1211

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255   649 IVQRhqqndWEAQLARAREELAAiqsqrelhaleLEKSLEMERESVAALNSeKASQEEQHR 709
Cdd:PRK04863 1212 AIEQ-----MEIELSRLTEELTS-----------REQKLAISSESVANIIR-KTIQREQNR 1255
PLN02939 PLN02939
transferase, transferring glycosyl groups
 227-607 2.30e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 2.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   227 SCKMQAYQTKLQLLGENPENITAALERSGQQLESEQLIDLEESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVT-EKYE 305
Cdd:PLN02939   55 APKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLV 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   306 AVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQReshnNEVKEQFKKLQATKQEVDAKLMATEHLLNTL 385
Cdd:PLN02939  135 GMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRL----SETDARIKLAAQEKIHVEILEEQLEKLRNEL 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   386 KESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQ--KQNEDRNTQASDSSEQLKK----LQAAVQDAESQLL-SKDQLLES 458
Cdd:PLN02939  211 LIRGATEGLCVHSLSKELDVLKEENMLLKDDIQflKAELIEVAETEERVFKLEKerslLDASLRELESKFIvAQEDVSKL 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   459 LRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKkssdsqtnEAQDQQKKLQAAKDEAeskllateellhslrNDYK 538
Cdd:PLN02939  291 SPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQ--------DLRDKVDKLEASLKEA---------------NVSK 347

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255   539 AQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINELraaKDEAEAKllSTEHSLNAL 607
Cdd:PLN02939  348 FSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKL---KEESKKR--SLEHPADDM 411
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 175-918 2.70e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 2.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  175 ELERDSSKARSVLVETQDKALRRISELREQctleQQAKAHLEEALRVEMDDMSCKMQAY--QTKLQLLGENPENITAALE 252
Cdd:COG3096  289 ELRRELFGARRQLAEEQYRLVEMARELEEL----SARESDLEQDYQAASDHLNLVQTALrqQEKIERYQEDLEELTERLE 364

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  253 RSGQQLE--SEQLIDLEESIGKSPLSTNG-SSGVSDLQRLLkerDEQLKSVTEKYEAVRKQEEENVLL---------LAQ 320
Cdd:COG3096  365 EQEEVVEeaAEQLAEAEARLEAAEEEVDSlKSQLADYQQAL---DVQQTRAIQYQQAVQALEKARALCglpdltpenAED 441

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  321 TKQAIHTELELKDTEVRKLQEKLkqleSQRESHNNEVKEQFKKLQATKQEV---DAKLMATEhLLNTLKEsYAIKEQQVV 397
Cdd:COG3096  442 YLAAFRAKEQQATEEVLELEQKL----SVADAARRQFEKAYELVCKIAGEVersQAWQTARE-LLRRYRS-QQALAQRLQ 515

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  398 TLEAQLEAI--RVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAvqdAESQLLSKDQLLESLRSEQAAKEQQLKHLKE 475
Cdd:COG3096  516 QLRAQLAELeqRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAE---LEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  476 QLGKLKQEN-------------------------------ENYLDKLRENKKSSD--SQTNEAQDQQ-KKLQAAKDEAES 521
Cdd:COG3096  593 RIKELAARApawlaaqdalerlreqsgealadsqevtaamQQLLEREREATVERDelAARKQALESQiERLSQPGGAEDP 672

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  522 KLLATEE------------------------LLHSLRN-----DYKAQEEKVALLEDKLKTL---SKENDVNVEKLHHIN 569
Cdd:COG3096  673 RLLALAErlggvllseiyddvtledapyfsaLYGPARHaivvpDLSAVKEQLAGLEDCPEDLyliEGDPDSFDDSVFDAE 752

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  570 EQREA---QSTDSQ---QKINEL----RAAKdEAEAKLLSTEHSLNALQAALSAKEEQAAS-LEQSLN---------ALK 629
Cdd:COG3096  753 ELEDAvvvKLSDRQwrySRFPEVplfgRAAR-EKRLEELRAERDELAEQYAKASFDVQKLQrLHQAFSqfvgghlavAFA 831

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  630 TESEHSLQDLRLHNDQLLEIVQRHQQND--WEAQLARAREELAAIQS-QRELHALE---LEKSLEMERESVAALNSEKAS 703
Cdd:COG3096  832 PDPEAELAALRQRRSELERELAQHRAQEqqLRQQLDQLKEQLQLLNKlLPQANLLAdetLADRLEELREELDAAQEAQAF 911

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  704 QeEQHRLKLEQLQREIQILQdqhanSESETVAALKGQLEALSQDLATSQASLLAkekelkasgnklnkIKKQHEQHQAKS 783
Cdd:COG3096  912 I-QQHGKALAQLEPLVAVLQ-----SDPEQFEQLQADYLQAKEQQRRLKQQIFA--------------LSEVVQRRPHFS 971

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  784 SDQSARLEALQSELADRLSHsRQVESEKEELQARVtgileeigtmqaQMQQVQDSHSELEREKRKLESRIESLQQE---- 859
Cdd:COG3096  972 YEDAVGLLGENSDLNEKLRA-RLEQAEEARREARE------------QLRQAQAQYSQYNQVLASLKSSRDAKQQTlqel 1038

                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255  860 ---------QVDSSAQdERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQ 918
Cdd:COG3096 1039 eqeleelgvQADAEAE-ERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQ 1105
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 589-1281 3.35e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 3.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    589 AKDEAEAKLLSTEHSLNALQAALSAK----EEQAASLEQSLNALKTEsehsLQDLRLHNDQLLEIVQRHQQN--DWEAQL 662
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESnelhEKQKFYLRQSVIDLQTK----LQEMQMERDAMADIRRRESQSqeDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    663 ARAREELAAIQSQRElhALELEKSLEMERESVAALNSEKASQEEQHRL-KLEQLQREIQILQDQHANSESETV-AALKGQ 740
Cdd:pfam15921  148 QNTVHELEAAKCLKE--DMLEDSNTQIEQLRKMMLSHEGVLQEIRSILvDFEEASGKKIYEHDSMSTMHFRSLgSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    741 LEALSQDLATSQASLLAKEKELKA-SGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSR--------QVESEK 811
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEAlKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARsqansiqsQLEIIQ 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    812 EELQARVTGILEEIGTMQAQMQQVQdshSELEREKRKLESRIESLQQEQVDSSAQdertsakLEEIQSENTKLAERNCLL 891
Cdd:pfam15921  306 EQARNQNSMYMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSE-------LTEARTERDQFSQESGNL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    892 EEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSklqNAQELMDHDHRTLQDKCDAYEKDKLLTK-----------HTLDC 960
Cdd:pfam15921  376 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDT---GNSITIDHLRRELDDRNMEVQRLEALLKamksecqgqmeRQMAA 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    961 LQSASEELHRVkANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQAT---ISNLREQLDAYKQ 1037
Cdd:pfam15921  453 IQGKNESLEKV-SSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATnaeITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1038 TEQGIQ------EKLQATNSSYTTQIATLEARWSAANSDVERLHE-------ANDALQLEMEQLKIKHGQEREEVKESIA 1104
Cdd:pfam15921  532 ELQHLKnegdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrTAGAMQVEKAQLEKEINDRRLELQEFKI 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1105 QKNRQVVELQEAMATRDRQLQEKIE----ASEKLAKFDEILIENEYLNKHTKQLEAELAESAELKEKLK----------- 1169
Cdd:pfam15921  612 LKDKKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnfrnkseeme 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1170 ----SLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQL 1245
Cdd:pfam15921  692 tttnKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEK 771

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 22024255   1246 HDKQIELAMSRDEQALLQAEADGLRQEVICLKEHLS 1281
Cdd:pfam15921  772 NKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVA 807
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 284-487 4.57e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.29  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   284 SDLQRLLKERDEQLKSVTekyeAVRKQ-EEENVLLLAQTKQ----AIHTELELKDTEVRKLQEKLKQLESQrESHNNEVK 358
Cdd:NF012221 1569 ADRQRLEQEKQQQLAAIS----GSQSQlESTDQNALETNGQaqrdAILEESRAVTKELTTLAQGLDALDSQ-ATYAGESG 1643

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   359 EQFKKLQA-------TKQEVDAKLMATEHLlNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQA--- 428
Cdd:NF012221 1644 DQWRNPFAgglldrvQEQLDDAKKISGKQL-ADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDAKADAekr 1722

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255   429 -SDSSEQLKKLQAAVQDAESqLLSKDQllesLRSEQAAKEQQLKHLKEQL-GKLKQENENY 487
Cdd:NF012221 1723 kDDALAKQNEAQQAESDANA-AANDAQ----SRGEQDASAAENKANQAQAdAKGAKQDESD 1778
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
520-726 5.19e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 5.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  520 ESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNveklhhineQREAQSTDSQQKINELRAAKDEAEAKLLS 599
Cdd:COG3206  167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV---------DLSEEAKLLLQQLSELESQLAEARAELAE 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  600 TEHSLNALQAALSAKEEQAASLEQS--LNALKTEsehsLQDLRLhndQLLEIVQRHQQNDweAQLARAREELAAIQSQRE 677
Cdd:COG3206  238 AEARLAALRAQLGSGPDALPELLQSpvIQQLRAQ----LAELEA---ELAELSARYTPNH--PDVIALRAQIAALRAQLQ 308

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255  678 LHALELEKSLEMERES----VAALNSEKASQEEQ------HRLKLEQLQREIQILQDQH 726
Cdd:COG3206  309 QEAQRILASLEAELEAlqarEASLQAQLAQLEARlaelpeLEAELRRLEREVEVARELY 367
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 796-931 7.71e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 7.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  796 ELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQ-EQVDSSAQDERTSAK- 873
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEArIKKYEEQLGNVRNNKe 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255  874 LEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQE 931
Cdd:COG1579   91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD 148
PRK12704 PRK12704
phosphodiesterase; Provisional
 361-493 8.22e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 8.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   361 FKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQQVvtLEAQLEAIRVENEqkvkdLQKQNEDRNtqasdssEQLKKLQA 440
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEAL--LEAKEEIHKLRNE-----FEKELRERR-------NELQKLEK 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 22024255   441 AVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRE 493
Cdd:PRK12704   90 RLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQ 142
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 597-869 9.90e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 9.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  597 LLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNdwEAQLARAREELAAIQSQR 676
Cdd:COG4942   15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL--EQELAALEAELAELEKEI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  677 ElhalELEKSLEMERESVAALNSEKASQEEQHRLKLeqlqreiqILQDQHANSESETVAALKGQLEALSQDLAtsqasll 756
Cdd:COG4942   93 A----ELRAELEAQKEELAELLRALYRLGRQPPLAL--------LLSPEDFLDAVRRLQYLKYLAPARREQAE------- 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  757 akekELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELadrlshsrqvESEKEELQARVTGILEEIGTMQAQMQQVQ 836
Cdd:COG4942  154 ----ELRADLAELAALRAELEAERAELEALLAELEEERAAL----------EALKAERQKLLARLEKELAELAAELAELQ 219

                        250       260       270
                 ....*....|....*....|....*....|...
gi 22024255  837 DSHSELEREKRKLESRIESLQQEQVDSSAQDER 869
Cdd:COG4942  220 QEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 607-1346 1.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  607 LQAALSAKEEQAASLEQslnalKTESEHSLQDLRlhnDQLLEIVQRhqQNDWEAQLARAREELAAIQSqrelhALELEKS 686
Cdd:COG3096  284 SERALELRRELFGARRQ-----LAEEQYRLVEMA---RELEELSAR--ESDLEQDYQAASDHLNLVQT-----ALRQQEK 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  687 LEMERESVAALNSEKASQEEQhrlkLEQLQREIQILQDQHANSESEtVAALKGQLEALSQDLATSQASLLAKEKELKASG 766
Cdd:COG3096  349 IERYQEDLEELTERLEEQEEV----VEEAAEQLAEAEARLEAAEEE-VDSLKSQLADYQQALDVQQTRAIQYQQAVQALE 423

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  767 N----------KLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGI------------LEE 824
Cdd:COG3096  424 KaralcglpdlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVersqawqtarelLRR 503

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  825 IGTMQAQMQQVQD---SHSELEREKRKLEsRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERncLLEEQTNHLE-- 899
Cdd:COG3096  504 YRSQQALAQRLQQlraQLAELEQRLRQQQ-NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEE--LEEQAAEAVEqr 580

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  900 SQLQAKQDEIG--------------KIQAKLQQvLDEHS--KLQNAQELMDHDHRTLQDKCDA-YEKDKLLTKHtlDCLQ 962
Cdd:COG3096  581 SELRQQLEQLRarikelaarapawlAAQDALER-LREQSgeALADSQEVTAAMQQLLEREREAtVERDELAARK--QALE 657

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  963 SASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAE--------RCAKLKAQNSESETQLQAtISNLREQL-- 1032
Cdd:COG3096  658 SQIERLSQPGGAEDPRLLALAERLGGVLLSEIYDDVTLEDAPYfsalygpaRHAIVVPDLSAVKEQLAG-LEDCPEDLyl 736

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1033 ----------DAYKQTEQG-----IQEKLQATNSSYTT-----------QIATLEA-------RWSAANSDV---ERLHE 1076
Cdd:COG3096  737 iegdpdsfddSVFDAEELEdavvvKLSDRQWRYSRFPEvplfgraarekRLEELRAerdelaeQYAKASFDVqklQRLHQ 816

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1077 A---------NDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMatrdRQLQEKIEASEKLAKFDEILiENEYL 1147
Cdd:COG3096  817 AfsqfvgghlAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQL----DQLKEQLQLLNKLLPQANLL-ADETL 891

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1148 NKHTKQLEAELAESAELK-------EKLKSLQCELYVLQEKAEQHAvqmaEKETQSATATAEVSELKKAIEEQAvELTRQ 1220
Cdd:COG3096  892 ADRLEELREELDAAQEAQafiqqhgKALAQLEPLVAVLQSDPEQFE----QLQADYLQAKEQQRRLKQQIFALS-EVVQR 966

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1221 KEHASFvteqSDAVQ-----KDLLQA-QQQLHDKQIELAMSRDEQALLQAEADGLRQEVICLKEhlSPSTDSDSLRSLne 1294
Cdd:COG3096  967 RPHFSY----EDAVGllgenSDLNEKlRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKS--SRDAKQQTLQEL-- 1038

                        810       820       830       840       850
                 ....*....|....*....|....*....|....*....|....*....|...
gi 22024255 1295 rlQRELEDLK-HKSAGAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQ 1346
Cdd:COG3096 1039 --EQELEELGvQADAEAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEM 1089
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 283-922 1.16e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    283 VSDLQRLLKERDEQLKSVTEKYEAVRKQEEEnvlllaqtkqaIHTELELKDTEVRKLQEKLKQLESQRESHN---NEVKE 359
Cdd:TIGR04523   56 LKNLDKNLNKDEEKINNSNNKIKILEQQIKD-----------LNDKLKKNKDKINKLNSDLSKINSEIKNDKeqkNKLEV 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    360 QFKKLQATKQEVDaklmatEHLLNTLKEsyaikeqqVVTLEAQLEAIRVENeqkvKDLQKQNEDRNTQASDSSEQLKKLQ 439
Cdd:TIGR04523  125 ELNKLEKQKKENK------KNIDKFLTE--------IKKKEKELEKLNNKY----NDLKKQKEELENELNLLEKEKLNIQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    440 AAVQDAESQLLSKDQLLESLRSeqaaKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEA 519
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKK----KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    520 ESkllaTEELLHSLRNDYKAQEEKVALLEDKLKTL-SKENDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLL 598
Cdd:TIGR04523  263 NK----IKKQLSEKQKELEQNNKKIKELEKQLNQLkSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    599 STEHSLNALQAALSAKEEQAASLEQSLNalktESEHSLQDLRLHNDQLLEIVQ--RHQQNDWEAQLARAREELAAIQSQr 676
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELE----EKQNEIEKLKKENQSYKQEIKnlESQINDLESKIQNQEKLNQQKDEQ- 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    677 eLHALELEKS-LEMERESVAALNSEKASQEEQHRLKLEQLQREIQILqDQHANSESETVAALKGQLEALSQDLATSQASL 755
Cdd:TIGR04523  414 -IKKLQQEKElLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNL-DNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    756 LAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVT--GILEEIGTMQAQMQ 833
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIE 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    834 QVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAK-------LEEIQSENTKLAERNCLLEEQTNHLESQLQAKQ 906
Cdd:TIGR04523  572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKisslekeLEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651

                          650
                   ....*....|....*.
gi 22024255    907 DEIGKIQAKLQQVLDE 922
Cdd:TIGR04523  652 ETIKEIRNKWPEIIKK 667
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
684-914 1.17e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 46.05  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  684 EKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQhansesetVAALKGQLEALSQDLATSQASLLAKEKELK 763
Cdd:COG4372   12 RLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREE--------LEQAREELEQLEEELEQARSELEQLEEELE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  764 ASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELE 843
Cdd:COG4372   84 ELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQ 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255  844 REKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQA 914
Cdd:COG4372  164 EELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLA 234
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1015-1421 1.45e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.61  E-value: 1.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1015 SESETQLQATI--SNLREQLDAYKQTEQGIQEK----LQATNSSYTT---QIATLEARWSAANSDVE--RLHEANDALQL 1083
Cdd:COG5022  745 DNIATRIQRAIrgRYLRRRYLQALKRIKKIQVIqhgfRLRRLVDYELkwrLFIKLQPLLSLLGSRKEyrSYLACIIKLQK 824

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1084 EME---QLKIKHGQEREEVKESIAQKnrqvvelqeamATRDRQLQEKIEASEKLAKFDEILIENEYLNKHTKQLEAELAE 1160
Cdd:COG5022  825 TIKrekKLRETEEVEFSLKAEVLIQK-----------FGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKS 893

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1161 SAELKEKLKSLQCELyvLQEKAEQHAVQMAEKETQsataTAEVSELKKAIEE------QAVELTRQKEHASFVTE----- 1229
Cdd:COG5022  894 ISSLKLVNLELESEI--IELKKSLSSDLIENLEFK----TELIARLKKLLNNidleegPSIEYVKLPELNKLHEVesklk 967

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1230 -----------QSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICLKEHlspSTDSDSLRSLNERLQR 1298
Cdd:COG5022  968 etseeyedllkKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAEL---QSASKIISSESTELSI 1044

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1299 ELedlkhKSAGAESNMQQEIEELQANNQQMAERIneletlragiqaqqllasmaPKNVQEAAAAGEKAELESKLKEIMNE 1378
Cdd:COG5022 1045 LK-----PLQKLKGLLLLENNQLQARYKALKLRR--------------------ENSLLDDKQLYQLESTENLLKTINVK 1099

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 22024255 1379 VQDVTNRNLFLEQKCENFLILEQSNERLKLQNAKLSRQLDETL 1421
Cdd:COG5022 1100 DLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTL 1142
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 532-1105 2.10e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    532 SLRNDYKAQEEKVALLEDKLKTLSKE---NDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQ 608
Cdd:TIGR04523   23 GYKNIANKQDTEEKQLEKKLKTIKNElknKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLN 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    609 AALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAR-EELAAIQSQRELHALELEKSL 687
Cdd:TIGR04523  103 SDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKyNDLKKQKEELENELNLLEKEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    688 EMERESVAALNSeKASQEEQHRLKLEQLQREIQILQDQHANSESETvAALKGQLEALSQDLATSQASLLAKEKELKASGN 767
Cdd:TIGR04523  183 LNIQKNIDKIKN-KLLKLELLLSNLKKKIQKNKSLESQISELKKQN-NQLKDNIEKKQQEINEKTTEISNTQTQLNQLKD 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    768 KLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKE-----ELQARVTGILEEIGTMQAQMQQVQDSHSEL 842
Cdd:TIGR04523  261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    843 EREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQL-------QAKQDEIGKIQAK 915
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIqnqeklnQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    916 LQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQRE 995
Cdd:TIGR04523  421 KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    996 QEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSyttqiaTLEARWSAANSDVERLH 1075
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE------NLEKEIDEKNKEIEELK 574

                          570       580       590
                   ....*....|....*....|....*....|
gi 22024255   1076 EANDALQLEMEQLKIKHGQEREEVKESIAQ 1105
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKE 604
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 744-985 2.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  744 LSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILE 823
Cdd:COG4942   11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  824 EIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERnclLEEQTNHLESQLQ 903
Cdd:COG4942   91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE---LRADLAELAALRA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  904 AKQDEIGKIQAKLQQVLDEHSKLQNAQElmdhdhrTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQD 983
Cdd:COG4942  168 ELEAERAELEALLAELEEERAALEALKA-------ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                 ..
gi 22024255  984 QQ 985
Cdd:COG4942  241 ER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 941-1190 2.64e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  941 QDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQ 1020
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1021 LQATISNLREQLDAYKQTEQGIQEKLQATNSSyttqiatlearWSAANSDVERLHEANDALQLEMEQLKiKHGQEREEVK 1100
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQPPLALLLSPED-----------FLDAVRRLQYLKYLAPARREQAEELR-ADLAELAALR 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1101 ESIAQKNRQVVELQEAMATRDRQLQEKIEASEKLakfdeilieneyLNKHTKQLEAELAESAELKEKLKSLQCELYVLQE 1180
Cdd:COG4942  167 AELEAERAELEALLAELEEERAALEALKAERQKL------------LARLEKELAELAAELAELQQEAEELEALIARLEA 234

                        250
                 ....*....|
gi 22024255 1181 KAEQHAVQMA 1190
Cdd:COG4942  235 EAAAAAERTP 244
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 240-529 2.73e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 2.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   240 LGENPENITAALersgQQLESEQLIDLEESIGKSPLS--TNGSSGVSDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLl 317
Cdd:PRK05771   14 LKSYKDEVLEAL----HELGVVHIEDLKEELSNERLRklRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELI- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   318 laqtkQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVK--EQFKKLqatkqEVDAKLmatehlLNTLKESYAIkeqq 395
Cdd:PRK05771   89 -----KDVEEELEKIEKEIKELEEEISELENEIKELEQEIErlEPWGNF-----DLDLSL------LLGFKYVSVF---- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   396 VVTL-EAQLEAIRVENEQKVKDLQKQNEDRNT--------QASDSSEQLKKLQaavqdaesqlLSKDQLLESLRSEQAak 466
Cdd:PRK05771  149 VGTVpEDKLEELKLESDVENVEYISTDKGYVYvvvvvlkeLSDEVEEELKKLG----------FERLELEEEGTPSEL-- 216

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255   467 eqqLKHLKEQLGKLKQENENYLDKLRE-NKKSSD--SQTNEAQDQQKKLQaakdEAESKLLATEEL 529
Cdd:PRK05771  217 ---IREIKEELEEIEKERESLLEELKElAKKYLEelLALYEYLEIELERA----EALSKFLKTDKT 275
46 PHA02562
endonuclease subunit; Provisional
 1008-1273 3.16e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 3.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1008 AKLKAQNSESETqLQATISNLREQLDAYKQTEQGIQEKlqatnssyttqiatlearwsaANSDVERLHEANDALQLEMEQ 1087
Cdd:PHA02562  174 DKIRELNQQIQT-LDMKIDHIQQQIKTYNKNIEEQRKK---------------------NGENIARKQNKYDELVEEAKT 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1088 LKikhgQEREEVKESIAQKNRQVVELQEAMA---TRDRQLQEKIEASEKLAKFDEiliENEYLNKHTKQLEAELAESAEL 1164
Cdd:PHA02562  232 IK----AEIEELTDELLNLVMDIEDPSAALNklnTAAAKIKSKIEQFQKVIKMYE---KGGVCPTCTQQISEGPDRITKI 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1165 KEKLKSLQCELyvlqEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRqkehasfVTEQSDAVQKDLLQAQQQ 1244
Cdd:PHA02562  305 KDKLKELQHSL----EKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLIT-------LVDKAKKVKAAIEELQAE 373

                         250       260
                  ....*....|....*....|....*....
gi 22024255  1245 LHDKQIELAMSRDEQALLQAEADGLRQEV 1273
Cdd:PHA02562  374 FVDNAEELAKLQDELDKIVKTKSELVKEK 402
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 659-1321 3.24e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 3.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    659 EAQLARAREELAAIQSQRELHALELEKSLemeRESVAALNSEKASQEEqhrlKLEQLQREIQILQDQHANSESETVAALK 738
Cdd:pfam12128  271 ETLIASRQEERQETSAELNQLLRTLDDQW---KEKRDELNGELSAADA----AVAKDRSELEALEDQHGAFLDADIETAA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    739 GQLEALSQdlatSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSAR-LEALQSELA------DRL-----SHSRQ 806
Cdd:pfam12128  344 ADQEQLPS----WQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRdIAGIKDKLAkirearDRQlavaeDDLQA 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    807 VESE-KEELQARVTGILEE-------IGTMQAQMQQVQDShSELEREKRKLESRIESLQQEQVD-----SSAQDERTSAK 873
Cdd:pfam12128  420 LESElREQLEAGKLEFNEEeyrlksrLGELKLRLNQATAT-PELLLQLENFDERIERAREEQEAanaevERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    874 ------LEEIQSENTKLAERNCLLEEqtnhLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMdhdHRTLQD--KCD 945
Cdd:pfam12128  499 krrdqaSEALRQASRRLEERQSALDE----LELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELL---HRTDLDpeVWD 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    946 AYEKDKL-LTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQAT 1024
Cdd:pfam12128  572 GSVGGELnLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNA 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1025 ISNLREQLDAYKQTEQGIQEKLQATNSSYTTQIATLEARWSAAnsdverLHEANDALQLEMEQLKIKHGQEREEVKESIA 1104
Cdd:pfam12128  652 RLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQL------DKKHQAWLEEQKEQKREARTEKQAYWQVVEG 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1105 QKNRQVVELQEAMATRDRQLQEKIEASEK-----LAKFDEILIENEYLNKHTKQLEAELAESAELKeklkslqcelyvlQ 1179
Cdd:pfam12128  726 ALDAQLALLKAAIAARRSGAKAELKALETwykrdLASLGVDPDVIAKLKREIRTLERKIERIAVRR-------------Q 792

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1180 EKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEhasfvteqsdavqkdllQAQQQLHDKQIELAMSRDEQ 1259
Cdd:pfam12128  793 EVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIA-----------------DTKLRRAKLEMERKASEKQQ 855

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22024255   1260 ALLQAEADGLRQEVICLKEHLSPSTDSDSLRSLNERLqRELEDLKHKSAGAESNMQQEIEEL 1321
Cdd:pfam12128  856 VRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERL-AQLEDLKLKRDYLSESVKKYVEHF 916
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 268-633 3.55e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.00  E-value: 3.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   268 ESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAV--RKQEEENVLLLAQTkQAIHTELElkdTEVRKLQEKLKQ 345
Cdd:NF033838   38 EEVRGGNNPTVTSSGNESQKEHAKEVESHLEKILSEIQKSldKRKHTQNVALNKKL-SDIKTEYL---YELNVLKEKSEA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   346 -LESQRESHNNEVKEQFKK---------LQATKQEVDAKLMATE--------HLLNTLKE-SYAIKEQQVVTLEAQLEAI 406
Cdd:NF033838  114 eLTSKTKKELDAAFEQFKKdtlepgkkvAEATKKVEEAEKKAKDqkeedrrnYPTNTYKTlELEIAESDVEVKKAELELV 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   407 RVE-----NEQKVKDLQKQNEDRNTQASdsseQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLK 481
Cdd:NF033838  194 KEEakeprDEEKIKQAKAKVESKKAEAT----RLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGV 269

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   482 QENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESkllateellhslrndykaqEEKVALLEDKLKTLSKENDVN 561
Cdd:NF033838  270 LGEPATPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEA-------------------EKKVEEAKKKAKDQKEEDRRN 330

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22024255   562 VEKLHHINEQREAQSTDSQQKINELRAAKDeaEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESE 633
Cdd:NF033838  331 YPTNTYKTLELEIAESDVKVKEAELELVKE--EAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEE 400
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 796-1211 3.69e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    796 ELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLEsRIESLQQEQvdssaQDERTSAKLE 875
Cdd:TIGR02169  157 KIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEK-----REYEGYELLK 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    876 EIQSentklaernclLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHsklqnaqelmdhdHRTLQDKCDAYEKDKLLTK 955
Cdd:TIGR02169  231 EKEA-----------LERQKEAIERQLASLEEELEKLTEEISELEKRL-------------EEIEQLLEELNKKIKDLGE 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    956 HTLDCLQSASEELHRVKANLDRELKEQDQQLselrerqreqeqqlKDQAERCAKLKAQNSEsetqLQATISNLREQLday 1035
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLERSIAEKEREL--------------EDAEERLAKLEAEIDK----LLAEIEELEREI--- 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1036 kQTEQGIQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQE 1115
Cdd:TIGR02169  346 -EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1116 AMATRDRQLQEKIE-ASEKLAKFDEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKET 1194
Cdd:TIGR02169  425 LNAAIAGIEAKINElEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504

                          410
                   ....*....|....*..
gi 22024255   1195 QSATATAEVSELKKAIE 1211
Cdd:TIGR02169  505 RVRGGRAVEEVLKASIQ 521
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 639-927 3.80e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 3.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    639 LRLHNDQLLEIVQRHQQNDwEAQLAR--AREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQhRLKLEQLq 716
Cdd:pfam17380  301 LRQEKEEKAREVERRRKLE-EAEKARqaEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEI-AMEISRM- 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    717 REIQILQDQHANSEsetvaalkgqlEALSQDL-ATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDqsarLEALQS 795
Cdd:pfam17380  378 RELERLQMERQQKN-----------ERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQRE----VRRLEE 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    796 ELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRK-LESRIESLQQEQVDSSAQDERTSAKL 874
Cdd:pfam17380  443 ERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKiLEKELEERKQAMIEEERKRKLLEKEM 522

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 22024255    875 EEIQSENTKLAERNCLLEEQTNHLEsqlqakQDEIGKIQAKLQQVLDEHSKLQ 927
Cdd:pfam17380  523 EERQKAIYEEERRREAEEERRKQQE------MEERRRIQEQMRKATEERSRLE 569
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
357-555 4.35e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 4.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  357 VKEQFKKLQATKQEVDAKLMA--TEHLLNTLKESYAIKEQQVVTLEAQLEAIR---VENEQKVKDLQKQNEDRNTQASDS 431
Cdd:COG3206  180 LEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARaelAEAEARLAALRAQLGSGPDALPEL 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  432 SEQlkklqAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLREnkkSSDSQTNEAQDQQKK 511
Cdd:COG3206  260 LQS-----PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILA---SLEAELEALQAREAS 331

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 22024255  512 LQAAKDEAESKLLATEEL---LHSLRNDYKAQEEKVALLEDKLKTLS 555
Cdd:COG3206  332 LQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
711-1109 4.59e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 4.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  711 KLEQLQREIQILQDQHA--NSESETVAALKGQLEALSQDLATSQASLLAKEKELKASgnKLNKIKKQHEQHQAKSSDQSA 788
Cdd:COG4717   72 ELKELEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLE 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  789 RLEALQSELADRLSHSRQVESEKEELQARVTGILEEIG-TMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQD 867
Cdd:COG4717  150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  868 ERTSAKLEEIQSENTKLAERNCLLEEQT----NHLESQLQAKQDEIGKIQAKLQQVL------DEHSKLQNAQELMDHDH 937
Cdd:COG4717  230 EQLENELEAAALEERLKEARLLLLIAAAllalLGLGGSLLSLILTIAGVLFLVLGLLallfllLAREKASLGKEAEELQA 309

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  938 RTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKA-----NLDRELKEQDQQLSELRERQREQEQQLKDQAERCAKL-- 1010
Cdd:COG4717  310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRieelqELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELra 389

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1011 KAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNssYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKI 1090
Cdd:COG4717  390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                        410       420
                 ....*....|....*....|....
gi 22024255 1091 KHG-----QEREEVKESIAQKNRQ 1109
Cdd:COG4717  468 DGElaellQELEELKAELRELAEE 491
46 PHA02562
endonuclease subunit; Provisional
 621-846 4.80e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 4.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   621 LEQSLNALKTESEHSLQDLRLHNDQLLEI-------VQRHQqNDWEAQLARAREeLAAIQSQRELHALELEKSLEMERES 693
Cdd:PHA02562  179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQrkkngenIARKQ-NKYDELVEEAKT-IKAEIEELTDELLNLVMDIEDPSAA 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   694 VAALNSEKAsqeeQHRLKLEQLQREIQILQD--------QHANSESETVAALKGQLEALSQDLatsqasllakeKELKAS 765
Cdd:PHA02562  257 LNKLNTAAA----KIKSKIEQFQKVIKMYEKggvcptctQQISEGPDRITKIKDKLKELQHSL-----------EKLDTA 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   766 GNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELERE 845
Cdd:PHA02562  322 IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401


                  .
gi 22024255   846 K 846
Cdd:PHA02562  402 K 402
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 284-469 5.06e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 5.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  284 SDLQRLLKERDEQLKSVTEKYEAVRKQE---EENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQ 360
Cdd:COG4942   30 EQLQQEIAELEKELAALKKEEKALLKQLaalERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  361 FKKLQATKQEVDAKLM---------------------ATEHLLNTLKESYAIKEQQVVTLEAQ---LEAIRVENEQKVKD 416
Cdd:COG4942  110 LRALYRLGRQPPLALLlspedfldavrrlqylkylapARREQAEELRADLAELAALRAELEAEraeLEALLAELEEERAA 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 22024255  417 LQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQ 469
Cdd:COG4942  190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1021-1388 5.09e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 5.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1021 LQATISNLREQLDAYKQTEQ---------GIQEKLQATNSSYTTQIATLEARWSAANSDVERLHEANdalQLEMEQLKIK 1091
Cdd:PRK10929   50 LQSALNWLEERKGSLERAKQyqqvidnfpKLSAELRQQLNNERDEPRSVPPNMSTDALEQEILQVSS---QLLEKSRQAQ 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1092 HGQER-EEVKESIAQKNRQVVELQEAMATRDRQLQE----------------KIEASEKLAKFDEIliENEYLNKHTKQ- 1153
Cdd:PRK10929  127 QEQDRaREISDSLSQLPQQQTEARRQLNEIERRLQTlgtpntplaqaqltalQAESAALKALVDEL--ELAQLSANNRQe 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1154 ---LEAELAE--SAELKEKLKSLQCELYVL-QEKAEQ---HAVQMAEketQSATATAEVSELKKAIEEQAVELTRQKEHA 1224
Cdd:PRK10929  205 larLRSELAKkrSQQLDAYLQALRNQLNSQrQREAERaleSTELLAE---QSGDLPKSIVAQFKINRELSQALNQQAQRM 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1225 SFVTEQSDAVQKDLLQAQQQLHdkqielAMSRDEQALLQAEADG--LRQEVICLKEHLSPST-DSDSLRSLNERLQreLE 1301
Cdd:PRK10929  282 DLIASQQRQAASQTLQVRQALN------TLREQSQWLGVSNALGeaLRAQVARLPEMPKPQQlDTEMAQLRVQRLR--YE 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1302 DLKHKSAGAESNMQQEIEELQANNQ-----QMAERINELETLRAGIQAQQL-LASMAPKNVQeaaaagekaeleskLKEI 1375
Cdd:PRK10929  354 DLLNKQPQLRQIRQADGQPLTAEQNrildaQLRTQRELLNSLLSGGDTLILeLTKLKVANSQ--------------LEDA 419

                         410
                  ....*....|...
gi 22024255  1376 MNEVQDVTNRNLF 1388
Cdd:PRK10929  420 LKEVNEATHRYLF 432
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 168-636 5.50e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 5.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    168 DLAKKYKELERDSSKARSVLVETQDKALRrISELREQC---TLEQQAKAHLEEALRVEMD-DMSCKMQAYQTKLQLLgEN 243
Cdd:pfam15921  385 DLHKREKELSLEKEQNKRLWDRDTGNSIT-IDHLRRELddrNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESL-EK 462

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    244 PENITAALERSGQQLESEqlidLEESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAVR-------------KQ 310
Cdd:pfam15921  463 VSSLTAQLESTKEMLRKV----VEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklqelqhlKN 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    311 EEENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKE-QFKKLQATKQEVDAKLMATEHLLNTLKESY 389
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAmQVEKAQLEKEINDRRLELQEFKILKDKKDA 618

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    390 AIKEQQVVTLEAQLEAIRVENEqkvkdlqkqnedrntqasdSSEQLKklqaAVQDAESQllsKDQLLESL---RSEQAAK 466
Cdd:pfam15921  619 KIRELEARVSDLELEKVKLVNA-------------------GSERLR----AVKDIKQE---RDQLLNEVktsRNELNSL 672

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    467 EQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVAL 546
Cdd:pfam15921  673 SEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQF 752

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    547 LEDKLKTLSKENDVNVEKLHHINEQREAQSTDSQQKINE---LRAAKDEAEAKLLSTEHSLNalQAALSAKEEQAASLEQ 623
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGElevLRSQERRLKEKVANMEVALD--KASLQFAECQDIIQRQ 830

                          490
                   ....*....|...
gi 22024255    624 SLNALKTESEHSL 636
Cdd:pfam15921  831 EQESVRLKLQHTL 843
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
659-858 5.61e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 5.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  659 EAQLARAREELAAIQSQRELHALELEKSLEMEResVAALNSEKA---SQEEQHRLKLEQLQREIQILQDQHAN-SESETV 734
Cdd:COG3206  188 RKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQ--LSELESQLAearAELAEAEARLAALRAQLGSGPDALPElLQSPVI 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  735 AALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQheqhqakssdqsarleaLQSELADRLShsrQVESEKEEL 814
Cdd:COG3206  266 QQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ-----------------LQQEAQRILA---SLEAELEAL 325

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 22024255  815 QARVTGILEEIGTMQAQMQ---QVQDSHSELEREKRKLESRIESLQQ 858
Cdd:COG3206  326 QAREASLQAQLAQLEARLAelpELEAELRRLEREVEVARELYESLLQ 372
46 PHA02562
endonuclease subunit; Provisional
 546-826 6.69e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 6.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   546 LLEDKLKTLSKENDVNVEKLHHINEQREAQstdsQQKINELRAAKDEAEAKLlstehslnalqaalSAKEEQAASLEQSL 625
Cdd:PHA02562  171 LNKDKIRELNQQIQTLDMKIDHIQQQIKTY----NKNIEEQRKKNGENIARK--------------QNKYDELVEEAKTI 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   626 NALKTESehslqdlrlhNDQLLEIVQrhQQNDWEAQLARAREELAAIQSQRELHALELE------------KSLEMERES 693
Cdd:PHA02562  233 KAEIEEL----------TDELLNLVM--DIEDPSAALNKLNTAAAKIKSKIEQFQKVIKmyekggvcptctQQISEGPDR 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   694 VAALNSEKAsqEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELkasgnklnkik 773
Cdd:PHA02562  301 ITKIKDKLK--ELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI----------- 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 22024255   774 kqhEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQArVTGILEEIG 826
Cdd:PHA02562  368 ---EELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGI-VTDLLKDSG 416
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 808-1230 6.95e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.24  E-value: 6.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    808 ESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAER 887
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    888 NCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEE 967
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    968 LHRVKANLDRELKEQdQQLSELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQ 1047
Cdd:TIGR04523  192 IKNKLLKLELLLSNL-KKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1048 ATNSSYTT---QIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQER-EEVKESIAQKNRQVVELQEAMATRDRQ 1123
Cdd:TIGR04523  271 EKQKELEQnnkKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKlEEIQNQISQNNKIISQLNEQISQLKKE 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1124 LQEKIEASEKLakfdeilieNEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEV 1203
Cdd:TIGR04523  351 LTNSESENSEK---------QRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420
                   ....*....|....*....|....*..
gi 22024255   1204 SELKKAIEEQAVELTRQKEHASFVTEQ 1230
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQ 448
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
286-506 7.00e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 7.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  286 LQRLLKERDEQLKSVTEKYEAVRKQE-----EENVLLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQRESHNNEVKEQ 360
Cdd:COG3206  180 LEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  361 FKklQATKQEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRvenEQKVKDLQKQNEDRNTQASDSSEQLKKLQA 440
Cdd:COG3206  260 LQ--SPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALR---AQLQQEAQRILASLEAELEALQAREASLQA 334

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255  441 AVQDAESQLlskdqlleslrSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQ 506
Cdd:COG3206  335 QLAQLEARL-----------AELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
PRK12705 PRK12705
hypothetical protein; Provisional
 714-867 7.48e-04

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.93  E-value: 7.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   714 QLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEAL 793
Cdd:PRK12705   31 LAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQLEER 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22024255   794 QSELADRlshsrqvESEKEELQARVTGILEEIGTM---QAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQD 867
Cdd:PRK12705  111 EKALSAR-------ELELEELEKQLDNELYRVAGLtpeQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERKAQN 180
PRK09039 PRK09039
peptidoglycan -binding protein;
573-725 9.89e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.03  E-value: 9.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   573 EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLleivqr 652
Cdd:PRK09039   73 RQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQI------ 146

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255   653 hqqndweAQLaraREELAAIQSqrelhALELEKSLEMERESVAA-----LNSEKASQ-EEQHRLKLEQLQREIQILQDQ 725
Cdd:PRK09039  147 -------AAL---RRQLAALEA-----ALDASEKRDRESQAKIAdlgrrLNVALAQRvQELNRYRSEFFGRLREILGDR 210
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
747-1222 1.13e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   747 DLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVT---GILE 823
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKeleELKE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   824 EIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERT-------------SAKLEEIQSENTKLAERNCL 890
Cdd:PRK03918  239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkelkekaeeyiklSEFYEEYLDELREIEKRLSR 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   891 LEEQTNHLESQLQ---AKQDEIGKIQAKLQQVLDEHSKLQNAQELMDhDHRTLQDKCDAYEKDklLTKHTLDCLQSASEE 967
Cdd:PRK03918  319 LEEEINGIEERIKeleEKEERLEELKKKLKELEKRLEELEERHELYE-EAKAKKEELERLKKR--LTGLTPEKLEKELEE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   968 LHRVKANLDRELKEQDQQLSELRERQREQ----------------------------------------EQQLKDQAERC 1007
Cdd:PRK03918  396 LEKAKEEIEEEISKITARIGELKKEIKELkkaieelkkakgkcpvcgrelteehrkelleeytaelkriEKELKEIEEKE 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1008 AKLKAQNSESETQL--QATISNLREQLDAYKQTEQGIQ----EKLQATNSSYTT---QIATLEARWSAANSDVERLHEAN 1078
Cdd:PRK03918  476 RKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKkynlEELEKKAEEYEKlkeKLIKLKGEIKSLKKELEKLEELK 555

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1079 DALQLEMEQLKIK-------HGQEREEVKESIAQKNRQVVELQEAMatrDRQLQEKIEASEKLAKFDEILIENEYLNKHT 1151
Cdd:PRK03918  556 KKLAELEKKLDELeeelaelLKELEELGFESVEELEERLKELEPFY---NEYLELKDAEKELEREEKELKKLEEELDKAF 632

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255  1152 KQLEAELAESAELKEKLKSLQCELYvlQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKE 1222
Cdd:PRK03918  633 EELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
PTZ00121 PTZ00121
MAEBL; Provisional
 616-1328 1.18e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   616 EQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARARE-ELAAIQSQRELHALELEKSLEMERESV 694
Cdd:PTZ00121 1027 EKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDfDFDAKEDNRADEATEEAFGKAEEAKKT 1106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   695 AALNSEKASQEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKK 774
Cdd:PTZ00121 1107 ETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE 1186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   775 QHEQHQAKSSDQSARLE-ALQSELADRLSHSRQVESEKEELQARVTgilEEIGTMQAQMQQVQDSHSELEREKRKlESRI 853
Cdd:PTZ00121 1187 VRKAEELRKAEDARKAEaARKAEEERKAEEARKAEDAKKAEAVKKA---EEAKKDAEEAKKAEEERNNEEIRKFE-EARM 1262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   854 ESLQQEQVDSSAQDERTSAKL----EEIQSENTKLAERNCLLEEQTNHLES-----QLQAKQDEIGKIQAKLQQVLDEHS 924
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELkkaeEKKKADEAKKAEEKKKADEAKKKAEEakkadEAKKKAEEAKKKADAAKKKAEEAK 1342

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   925 KLQNA----QELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHR---VKANLDRELKEQDQQLSELRERQREQE 997
Cdd:PTZ00121 1343 KAAEAakaeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKadeAKKKAEEDKKKADELKKAAAAKKKADE 1422

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   998 QQLKDQAERCA---KLKAQNSESETQLQATISNLREQLDAYKQTEQGIQEKLQATNSSYTTQIATLEARWSAANSDVERL 1074
Cdd:PTZ00121 1423 AKKKAEEKKKAdeaKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1075 HEANDALQLEMEQLKIKHGQEREEVKEsiAQKNRQVVELQEAMATR---DRQLQEKIEASEKLAKFDEILIENEYLNKHT 1151
Cdd:PTZ00121 1503 KKAAEAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKKAEEKKkadELKKAEELKKAEEKKKAEEAKKAEEDKNMAL 1580

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1152 KQLE-AELAESAELKEKLKSLQCELYVLQE----------------KAEQHAVQMAEKETQSATATAEVSELKKAIEEQA 1214
Cdd:PTZ00121 1581 RKAEeAKKAEEARIEEVMKLYEEEKKMKAEeakkaeeakikaeelkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1215 V---ELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIElamSRDEQALLQAEADGLRQEVICLKEHLSPSTDSDSLRS 1291
Cdd:PTZ00121 1661 IkaaEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE---AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKK 1737

                         730       740       750
                  ....*....|....*....|....*....|....*..
gi 22024255  1292 LNERLQRELEDLKhKSAGAESNMQQEIEELQANNQQM 1328
Cdd:PTZ00121 1738 EAEEDKKKAEEAK-KDEEEKKKIAHLKKEEEKKAEEI 1773
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 328-1153 1.23e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.63  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    328 ELELKDTEVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKEsyaikeqQVVTLEAQLEAIR 407
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE-------QIAELQAQIAELR 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    408 VENEQKVKDLQkqneDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENY 487
Cdd:pfam01576  236 AQLAKKEEELQ----AALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDT 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    488 LD--------------KLRENKKSSDSQTN----EAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLED 549
Cdd:pfam01576  312 LDttaaqqelrskreqEVTELKKALEEETRsheaQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQA 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    550 KLKTLSKENdvnvEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALK 629
Cdd:pfam01576  392 ELRTLQQAK----QDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    630 TEsehslqdlrLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHAlELEKSLEMERESVAALNSEKASQEEQHR 709
Cdd:pfam01576  468 SQ---------LQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEE-EAKRNVERQLSTLQAQLSDMKKKLEEDA 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    710 LKLEQ-------LQREIQILQDQHANSESE------TVAALKGQLEALSQDLATSQASLLAKEKELKasgnKLNKIKKQH 776
Cdd:pfam01576  538 GTLEAleegkkrLQRELEALTQQLEEKAAAydklekTKNRLQQELDDLLVDLDHQRQLVSNLEKKQK----KFDQMLAEE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    777 EQHQAKSSDQSARLEALQSELADR-LSHSRQVESE---KEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESR 852
Cdd:pfam01576  614 KAISARYAEERDRAEAEAREKETRaLSLARALEEAleaKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQ 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    853 IESLQ---QEQVDSSAQDERTSAKLE------------EIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIG------- 910
Cdd:pfam01576  694 VEEMKtqlEELEDELQATEDAKLRLEvnmqalkaqferDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAqavaakk 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    911 KIQAKLQQVLDEHSKLQNAQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLSELR 990
Cdd:pfam01576  774 KLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    991 ERQREQEQQLKDQAERCAKLKAQNS---ESETQLQATISNLREQLDaykqTEQGIQEKLQATNSSYTTQIATLEARWSAA 1067
Cdd:pfam01576  854 RARRQAQQERDELADEIASGASGKSalqDEKRRLEARIAQLEEELE----EEQSNTELLNDRLRKSTLQVEQLTTELAAE 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   1068 NSDVERLHEANDALQLEMEQLKIK----HGQEREEVKESIAQKNRQVVELQEA--MATRDRQLQEKIeASEKLAKFDEIL 1141
Cdd:pfam01576  930 RSTSQKSESARQQLERQNKELKAKlqemEGTVKSKFKSSIAALEAKIAQLEEQleQESRERQAANKL-VRRTEKKLKEVL 1008

                          890
                   ....*....|..
gi 22024255   1142 IENEYLNKHTKQ 1153
Cdd:pfam01576 1009 LQVEDERRHADQ 1020
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 186-701 1.33e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    186 VLVETQDKAlrriSELREQCTLEQQAKAHLEEA---LRVEMDDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESEQ 262
Cdd:pfam05483  262 LLEESRDKA----NQLEEKTKLQDENLKELIEKkdhLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQM 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    263 LIDLEESIGKSPLSTNGSSGVSDLQRLLKERDEQLKSVTEKYEAV------RKQEEENVLLLAQTKQAIHTELELKDTEV 336
Cdd:pfam05483  338 EELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIItmelqkKSSELEEMTKFKNNKEVELEELKKILAED 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    337 RKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDAklMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR-VENEQKVK 415
Cdd:pfam05483  418 EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHD--LEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKnIELTAHCD 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    416 DLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENK 495
Cdd:pfam05483  496 KLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENA 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    496 KSSDSQTNEAQDQQKKLQAA----KDEAESKLLATEELLH---SLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHI 568
Cdd:pfam05483  576 RSIEYEVLKKEKQMKILENKcnnlKKQIENKNKNIEELHQenkALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEI 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    569 NEQREAQSTDsqQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKE---EQAASLEQSLNALKTESEHSLQDLRLHNDQ 645
Cdd:pfam05483  656 IDNYQKEIED--KKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHkiaEMVALMEKHKHQYDKIIEERDSELGLYKNK 733

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255    646 LLEivQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEK 701
Cdd:pfam05483  734 EQE--QSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 780-987 1.42e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  780 QAKSSDQSARLEALQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQE 859
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  860 QVDSSAQDERTSAKLEEI-----------QSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSKLQN 928
Cdd:COG4942   99 LEAQKEELAELLRALYRLgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 22024255  929 AQELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQQLS 987
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 322-925 1.48e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    322 KQAIHTELELKDTEvRKLQEKLKQLESQRES------HNNEVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAikeqq 395
Cdd:pfam05483   92 KWKVSIEAELKQKE-NKLQENRKIIEAQRKAiqelqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCA----- 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    396 vvtleaqleairvENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQllskdqlleslrSEQAAKEQQLKhLKE 475
Cdd:pfam05483  166 -------------RSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQ------------AENARLEMHFK-LKE 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    476 QLGKLKQENENYldklrenkkssDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLS 555
Cdd:pfam05483  220 DHEKIQHLEEEY-----------KKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELI 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    556 KENDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHS 635
Cdd:pfam05483  289 EKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    636 LQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQL 715
Cdd:pfam05483  369 QQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAR 448

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    716 QREIQILQDQHANSESETVAALKGqlealSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQhqaKSSDQSARLEALQS 795
Cdd:pfam05483  449 EKEIHDLEIQLTAIKTSEEHYLKE-----VEDLKTELEKEKLKNIELTAHCDKLLLENKELTQ---EASDMTLELKKHQE 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    796 ELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQD-----------SHSELEREKRKLESRIESLQQEQVDSS 864
Cdd:pfam05483  521 DIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDevkckldkseeNARSIEYEVLKKEKQMKILENKCNNLK 600

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22024255    865 AQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHSK 925
Cdd:pfam05483  601 KQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQK 661
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 845-1183 1.69e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.92  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   845 EKRKLESRIESLQQEQVDSSaqdERTSAKLEEIQSEntklaerncLLEEQTNHLESQLQAKQDEIGkIQAKLQQVLDEHS 924
Cdd:PLN03229  430 PVRELEGEVEKLKEQILKAK---ESSSKPSELALNE---------MIEKLKKEIDLEYTEAVIAMG-LQERLENLREEFS 496

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   925 KLQNAQELMdhdHRTLQDKCDAY--EKDKLLT--------KHTLDCLQsaseELHRVKANLdrELKEQDQQLSELRERQR 994
Cdd:PLN03229  497 KANSQDQLM---HPVLMEKIEKLkdEFNKRLSrapnylslKYKLDMLN----EFSRAKALS--EKKSKAEKLKAEINKKF 567

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   995 EQEQQLKDQAERCAKLKAQNSESETqlqATISNLREQL-DAYKQTEQGIQEKLQATNSSYTTQIATLEARWSAANSDVer 1073
Cdd:PLN03229  568 KEVMDRPEIKEKMEALKAEVASSGA---SSGDELDDDLkEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDTAEQT-- 642

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  1074 lheANDALQLEMEQLKIKHGQEREEVKESIAQKNR---QVVELQEAMATRDRQLQEKIEAseklakfdeilieneyLNKH 1150
Cdd:PLN03229  643 ---PPPNLQEKIESLNEEINKKIERVIRSSDLKSKielLKLEVAKASKTPDVTEKEKIEA----------------LEQQ 703

                         330       340       350
                  ....*....|....*....|....*....|...
gi 22024255  1151 TKQLEAELAESAELKEKLKSLQCELYVLQEKAE 1183
Cdd:PLN03229  704 IKQKIAEALNSSELKEKFEELEAELAAARETAA 736
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
473-817 1.90e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 1.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  473 LKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLK 552
Cdd:COG4372    4 LGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  553 TLSKEndvnVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTES 632
Cdd:COG4372   84 ELNEQ----LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  633 EHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKL 712
Cdd:COG4372  160 ESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  713 EQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEA 792
Cdd:COG4372  240 DALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLA 319

                        330       340
                 ....*....|....*....|....*
gi 22024255  793 LQSELADRLSHSRQVESEKEELQAR 817
Cdd:COG4372  320 ALLELAKKLELALAILLAELADLLQ 344
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 711-821 1.97e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 1.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  711 KLEQLQREIQILQDQHANSESETVAALKGQLEALSQDLAtsqaSLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARL 790
Cdd:COG0542  419 RLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELE----ALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494

                         90       100       110
                 ....*....|....*....|....*....|...
gi 22024255  791 EALQSELADRLSHSRQVESEKE--ELQARVTGI 821
Cdd:COG0542  495 AELEEELAELAPLLREEVTEEDiaEVVSRWTGI 527
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 303-922 2.04e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    303 KYEAVRKQEEENVLLLAQTKQAIHTELELKDTEVRKLQEKLK------------QLESQRESHNNEV-----KEQFKKLQ 365
Cdd:pfam10174   43 KERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDELRaqrdlnqllqqdFTTSPVDGEDKFStpeltEENFRRLQ 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    366 AtkqEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIR--VENEQKVKDLQKQNEDRNTQAsdssEQLKKLQAAVQ 443
Cdd:pfam10174  123 S---EHERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKklLEMLQSKGLPKKSGEEDWERT----RRIAEAEMQLG 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    444 DAESQLLSKDQLLESLRSEQAAKE------------QQLKHLKE-QLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQK 510
Cdd:pfam10174  196 HLEVLLDQKEKENIHLREELHRRNqlqpdpaktkalQTVIEMKDtKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIK 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    511 KLQAAKdeAESKLLATEelLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQstdsQQKINELRAAK 590
Cdd:pfam10174  276 QMEVYK--SHSKFMKNK--IDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAK----EQRAAILQTEV 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    591 DEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTE---SEHSLQDLRLHNDQLLEivqrhQQNDWEAQLARARE 667
Cdd:pfam10174  348 DALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMldvKERKINVLQKKIENLQE-----QLRDKDKQLAGLKE 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    668 ELAAIQ---SQRELHALELEKSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQ------HANSESETVAALK 738
Cdd:pfam10174  423 RVKSLQtdsSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDLKEKvsalqpELTEKESSLIDLK 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    739 GQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQakssdQSARLEALQSELADRLSHsrqvesekeeLQARV 818
Cdd:pfam10174  503 EHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAH-----NAEEAVRTNPEINDRIRL----------LEQEV 567

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    819 TGILEEIGTMQAQMQQVQDSHSELEREKRKLESRIESLQQEQVDSSAQDERTSAKLEEIQSENTK--LAERNCLLEEQTN 896
Cdd:pfam10174  568 ARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKkgAQLLEEARRREDN 647

                          650       660
                   ....*....|....*....|....*.
gi 22024255    897 HLESQLQAKQDEIGKIQAKLQQVLDE 922
Cdd:pfam10174  648 LADNSQQLQLEELMGALEKTRQELDA 673
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 356-984 2.05e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    356 EVKEQFKKLQATKQEVDAKLMATEHLLNTLKESYAIKEQqvvTLEAQLEAIRVENEQkvkdlQKQNEDRNTQASDSSEQL 435
Cdd:TIGR00618  184 MEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQ---VLEKELKHLREALQQ-----TQQSHAYLTQKREAQEEQ 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    436 KKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLK---------------EQLGKLKQENENYLDKLRENKKSSDS 500
Cdd:TIGR00618  256 LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPlaahikavtqieqqaQRIHTELQSKMRSRAKLLMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    501 QTNEAQDQQKKLQAAKDEAESKLLATEELL---------HSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQ 571
Cdd:TIGR00618  336 QQSSIEEQRRLLQTLHSQEIHIRDAHEVATsireiscqqHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    572 R-------------EAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQD 638
Cdd:TIGR00618  416 TsafrdlqgqlahaKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLAR 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    639 LRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALN------SEKASQEEQHRLKL 712
Cdd:TIGR00618  496 LLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERkqraslKEQMQEIQQSFSIL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    713 EQLQREIQILQDQHANSESETVAALKGQLEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHEQHQAKSSDQSARLEA 792
Cdd:TIGR00618  576 TQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTL 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    793 LQSELADRLSHSRQVESEK-----------EELQARVTGILEEIGTMQAQMQQVQDSHSELERE-----------KRKLE 850
Cdd:TIGR00618  656 TQERVREHALSIRVLPKELlasrqlalqkmQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREfneienassslGSDLA 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    851 SRIESLQQEQVDSSAQDERTSAKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDEHsklqnaQ 930
Cdd:TIGR00618  736 AREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEI------G 809

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 22024255    931 ELMDHDHRTLQDKCDAYEKDKLLTKHTLDCLQSASEELHRVKANLDRELKEQDQ 984
Cdd:TIGR00618  810 QEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQ 863
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
335-681 2.27e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  335 EVRKLQEKLKQLESQRESHNNEVKEQFKKLQATKQEVDA---KLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENE 411
Cdd:COG4372   32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQarsELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  412 QkvkdLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLrseqaakEQQLKHLKEQLGKLKQENENYLDKL 491
Cdd:COG4372  112 E----LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKEL-------EEQLESLQEELAALEQELQALSEAE 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  492 RENKKSSDSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQ 571
Cdd:COG4372  181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEI 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  572 REAQSTDSQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQ 651
Cdd:COG4372  261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELA 340

                        330       340       350
                 ....*....|....*....|....*....|
gi 22024255  652 RHQQNDWEAQLARAREELAAIQSQRELHAL 681
Cdd:COG4372  341 DLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 197-515 2.38e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    197 RISELREQCTLEQQAKAHLEEALRVEMDDMSCKMQAYQTKlqllgenpENITAALERSGQQLESEQLIDLEESIGKSPLS 276
Cdd:pfam17380  300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQ--------ERMAMERERELERIRQEERKRELERIRQEEIA 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    277 TNGSSgVSDLQRLLKERDEQLKSVTEKYEAVRKQEeenvlLLAQTKQAIHTELELKDTEVRKLQEKLKQLESQREShnne 356
Cdd:pfam17380  372 MEISR-MRELERLQMERQQKNERVRQELEAARKVK-----ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE---- 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    357 vKEQFKKLQATKQEVdaklMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVENEQKVKDLQKQNEDRNTQASDSSEQLK 436
Cdd:pfam17380  442 -EERAREMERVRLEE----QERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    437 KLQAAVQDAESQLLSKDQLLESLRSEQAAKE-QQLKHLKEQLGKLKQENENyLDKLrENKKSSDSQTNEAQDQQKKLQAA 515
Cdd:pfam17380  517 LLEKEMEERQKAIYEEERRREAEEERRKQQEmEERRRIQEQMRKATEERSR-LEAM-EREREMMRQIVESEKARAEYEAT 594
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 499-640 2.84e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 2.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  499 DSQTNEAQDQQKKLQAAKDEAESKLLATEELLHSLRNDYKAQEEKVALLEDKLKTLSKENDVNVEKLHHINEQREAQSTd 578
Cdd:COG1579   16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAL- 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22024255  579 sQQKINELRAAKDEAEAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLR 640
Cdd:COG1579   95 -QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 580-970 3.16e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   580 QQKINELRAAKDEAEAKLLstehslNALQAALSAKEEQAASLEQSLNALKTESEHS--LQDLRlhnDQLLEivQRHQQND 657
Cdd:PRK10929   29 TQELEQAKAAKTPAQAEIV------EALQSALNWLEERKGSLERAKQYQQVIDNFPklSAELR---QQLNN--ERDEPRS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   658 WEAQLARAREELAAIQSQRELhaLELEKSLEME----RESVAALNSEKASQEEQHRLkLEQLQREIQIL--------QDQ 725
Cdd:PRK10929   98 VPPNMSTDALEQEILQVSSQL--LEKSRQAQQEqdraREISDSLSQLPQQQTEARRQ-LNEIERRLQTLgtpntplaQAQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   726 HANSESEtVAALKGQLEALS---------QDLATSQASLLAK-----EKELKASGNKLNkIKKQHEQHQA-KSSDQSARL 790
Cdd:PRK10929  175 LTALQAE-SAALKALVDELElaqlsannrQELARLRSELAKKrsqqlDAYLQALRNQLN-SQRQREAERAlESTELLAEQ 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   791 EA-LQSELADRLSHSRQVESEKEELQARVTGILEEIGTMQAQMQQVQDSHSELEREKRKL-ESRI--ESLQqeqvdssAQ 866
Cdd:PRK10929  253 SGdLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLgVSNAlgEALR-------AQ 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   867 DERTS--AKLEEIQSENTKLAERNCLLEEQTNHLESQLQAKQDEIGKIQAKLQQVLDehSKLQNAQELMDhdhrTLQDKC 944
Cdd:PRK10929  326 VARLPemPKPQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNRILD--AQLRTQRELLN----SLLSGG 399

                         410       420       430
                  ....*....|....*....|....*....|
gi 22024255   945 DA----YEKDKLLTKHTLDCLQSASEELHR 970
Cdd:PRK10929  400 DTlileLTKLKVANSQLEDALKEVNEATHR 429
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 407-718 3.37e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.80  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    407 RVENEQKVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQ---LGKLKQE 483
Cdd:pfam07888   68 REQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDiktLTQRVLE 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    484 NENYLDKLRENKKSSDSQTNEAQDQQKKLQAakdeaesKLLATEELLHSLRNDYKaqeekvalledKLKTLSKENDVNVE 563
Cdd:pfam07888  148 RETELERMKERAKKAGAQRKEEEAERKQLQA-------KLQQTEEELRSLSKEFQ-----------ELRNSLAQRDTQVL 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    564 KLHHINEQREAQSTDSQQKINELRAAKDEaeakllstehsLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLhn 643
Cdd:pfam07888  210 QLQDTITTLTQKLTTAHRKEAENEALLEE-----------LRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQ-- 276

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22024255    644 dqlleivQRHQQNDWEAQLARAREELAAIQSQRELHALELEKSLEMERESVAALNSEKASQEEqhRLKLEQLQRE 718
Cdd:pfam07888  277 -------ARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEE--RLQEERMERE 342
COG5022 COG5022
Myosin heavy chain [General function prediction only];
341-955 3.46e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  341 EKLKQLESQRESHNNEVKEQFKKLQATKQEVDAKLMAtehLLNTLKESYAIKEQQVVTLEAQL---EAIRVEN-EQKVKD 416
Cdd:COG5022  810 KEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEV---LIQKFGRSLKAKKRFSLLKKETIylqSAQRVELaERQLQE 886

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  417 LQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQL----------------LESLRSEQAAKEQQLKHLKEQLGKL 480
Cdd:COG5022  887 LKIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFkteliarlkkllnnidLEEGPSIEYVKLPELNKLHEVESKL 966

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  481 KQENENYLDKLRENKKS-SDSQT------------NEAQDQQKKLQAAKDEAESKLLATEElLHSLRNDYKAQEEKVALL 547
Cdd:COG5022  967 KETSEEYEDLLKKSTILvREGNKanselknfkkelAELSKQYGALQESTKQLKELPVEVAE-LQSASKIISSESTELSIL 1045

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  548 --EDKLK-TLSKENDVNVEKLHHINEQREAQSTDSQQKINELRAAKDEAEAKLLSTEhsLNALQAALSAKEEQAASLEQS 624
Cdd:COG5022 1046 kpLQKLKgLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLE--VTNRNLVKPANVLQFIVAQMI 1123

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  625 LNALKTESEHSlqdLRLHNDQLLEIVQRHQQNDWEAqlararEELAAIQSQRELHALELEKSLEMERESVAALNSEK--A 702
Cdd:COG5022 1124 KLNLLQEISKF---LSQLVNTLEPVFQKLSVLQLEL------DGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKskL 1194

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  703 SQEEQHRLK-----LEQLQREIQILQDQHANSESETVAAlkgqlEALSQDLATSQASLLAKEKELKASGNKLNKIKKQHE 777
Cdd:COG5022 1195 SSSEVNDLKneliaLFSKIFSGWPRGDKLKKLISEGWVP-----TEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSID 1269

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  778 QhqaksSDQSARLEALQSELADRLSHSRQVESEKEELQARvtgilEEIGTMQAQMQQVQDSHSELEREKRKLESRI-ESL 856
Cdd:COG5022 1270 N-----LLSSYKLEEEVLPATINSLLQYINVGLFNALRTK-----ASSLRWKSATEVNYNSEELDDWCREFEISDVdEEL 1339

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  857 QQ--EQVDSSAQDERTSAKLEEIQS--ENTKLAERNCLLEE-----QTNHLESQLQAKQDEIGKIQaKLQQVLDEHSKLQ 927
Cdd:COG5022 1340 EEliQAVKVLQLLKDDLNKLDELLDacYSLNPAEIQNLKSRydpadKENNLPKEILKKIEALLIKQ-ELQLSLEGKDETE 1418

                        650       660
                 ....*....|....*....|....*....
gi 22024255  928 -NAQELMDHDHRTLQDKCDAYEKDKLLTK 955
Cdd:COG5022 1419 vHLSEIFSEEKSLISLDRNSIYKEEVLSS 1447
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1072-1202 4.14e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 4.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1072 ERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIEASEKL---------AKFDEILI 1142
Cdd:COG2433  384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLerelsearsEERREIRK 463

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22024255 1143 ENEY--LNKHTKQLEAELAE----SAELKEKLKSLQcELYVLQEKAEQHAVQMAEKETQSATATAE 1202
Cdd:COG2433  464 DREIsrLDREIERLERELEEererIEELKRKLERLK-ELWKLEHSGELVPVKVVEKFTKEAIRRLE 528
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1134-1346 4.30e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 4.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1134 LAKFDEILIENEYLNKHTKQLEAELAESAELKEKLKSLQCELYVLQEKAEQHAVQMAEKETQSATATAEVSELKKAIEEQ 1213
Cdd:COG4942   16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1214 AVELTRQKEH------ASFVTEQSDAVQkdLLQAQQQLHDKQIELAMSRDEQALLQAEADGLRQEVICL----KEHLSPS 1283
Cdd:COG4942   96 RAELEAQKEElaellrALYRLGRQPPLA--LLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELaalrAELEAER 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22024255 1284 TDSDSLRSLNERLQRELEDLKHKSAGAESNMQQEIEELQANNQQMAERINELETLRAGIQAQQ 1346
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 657-799 4.41e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 40.87  E-value: 4.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    657 DWEAQLARAREELAAIQSQRELHALELE--KSLEMERESVAALNSEKASQEEQHRLKLEQLQREIQILQDQHANSES--- 731
Cdd:pfam00529   55 DYQAALDSAEAQLAKAQAQVARLQAELDrlQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVlap 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    732 -------------ETVAALKGQLEALSQDLATSQASLLAKEKELKASgnklnkIKKQHEQHQAKSSDQSARLEALQSELA 798
Cdd:pfam00529  135 iggisreslvtagALVAQAQANLLATVAQLDQIYVQITQSAAENQAE------VRSELSGAQLQIAEAEAELKLAKLDLE 208


                   .
gi 22024255    799 D 799
Cdd:pfam00529  209 R 209
PRK05431 PRK05431
seryl-tRNA synthetase; Provisional
 237-346 4.62e-03

seryl-tRNA synthetase; Provisional


Pssm-ID: 235461 [Multi-domain]  Cd Length: 425  Bit Score: 41.21  E-value: 4.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   237 LQLLGENPENITAALERSGQQLESEQLIDLEESIGKSplstngssgVSDLQRLLKERdeqlKSVTEKYEAVRKQEEENVL 316
Cdd:PRK05431    4 IKLIRENPEAVKEALAKRGFPLDVDELLELDEERREL---------QTELEELQAER----NALSKEIGQAKRKGEDAEA 70

                          90       100       110
                  ....*....|....*....|....*....|
gi 22024255   317 LLAQTKQaIHTELELKDTEVRKLQEKLKQL 346
Cdd:PRK05431   71 LIAEVKE-LKEEIKALEAELDELEAELEEL 99
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 586-752 5.35e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 40.87  E-value: 5.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    586 LRAAKDEAEAKLLSTEHSLNALQAALsakeEQAASLEQSLNALKTESEHSLQDLRlhndQLLEIVQRHQqndweAQLARA 665
Cdd:pfam00529   56 YQAALDSAEAQLAKAQAQVARLQAEL----DRLQALESELAISRQDYDGATAQLR----AAQAAVKAAQ-----AQLAQA 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255    666 REELAAIQSQRELHALELEKSLEMERESVAALNSEKAS--QEEQHRLKLEQLQREIQILQDQHANSESETVAALKGQLEA 743
Cdd:pfam00529  123 QIDLARRRVLAPIGGISRESLVTAGALVAQAQANLLATvaQLDQIYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKL 202


                   ....*....
gi 22024255    744 LSQDLATSQ 752
Cdd:pfam00529  203 AKLDLERTE 211
PRK11281 PRK11281
mechanosensitive channel MscK;
197-468 5.55e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 5.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   197 RISELREQCTLEQQAKA---HLEEALrvemdDMSCKMQAYQTKLQLLGENPENITAALERSGQQLESeqlidLEESIGKS 273
Cdd:PRK11281   44 QLDALNKQKLLEAEDKLvqqDLEQTL-----ALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA-----LKDDNDEE 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   274 PLSTNGSSGVSDLQRLLKERDEQLKSVtekyeavrkQE---EENVLLLAQTKQAIHTELELKDTEVRkLQEKLKQLESQR 350
Cdd:PRK11281  114 TRETLSTLSLRQLESRLAQTLDQLQNA---------QNdlaEYNSQLVSLQTQPERAQAALYANSQR-LQQIRNLLKGGK 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   351 ESHNNEVKEQFKKLQATKQEVDAK-------LMATEHLLNTLKESYAIKEQQVVTLEAQLEAI--------RVENEQKVK 415
Cdd:PRK11281  184 VGGKALRPSQRVLLQAEQALLNAQndlqrksLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLqeainskrLTLSEKTVQ 263

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22024255   416 DLQKQNE--------------DRNTQASDS-SEQLKKLQAAVQDaesQLLSKDQLLESLRSEQAAKEQ 468
Cdd:PRK11281  264 EAQSQDEaariqanplvaqelEINLQLSQRlLKATEKLNTLTQQ---NLRVKNWLDRLTQSERNIKEQ 328
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 369-493 5.68e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 5.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  369 QEVDAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVE----------NEQKVKDLQ---KQNEDRNTQASDSSE-- 433
Cdd:COG1579   13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTEledlekeikrLELEIEEVEariKKYEEQLGNVRNNKEye 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22024255  434 ----QLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRE 493
Cdd:COG1579   93 alqkEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 456-570 6.02e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 6.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   456 LESLRSEQAAKEQQLKHLKEQLGKLKQEnenYLDKLRENKKSSDSQTNEAQDQ-QKKLQAAKDEAESKLLATEELLHSLR 534
Cdd:PRK00409  525 LEELERELEQKAEEAEALLKEAEKLKEE---LEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQLQKGGY 601

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 22024255   535 NDYKAQE--EKVALLEDKLKTLSKENDVNVEKLHHINE 570
Cdd:PRK00409  602 ASVKAHEliEARKRLNKANEKKEKKKKKQKEKQEELKV 639
ZntB-like_1 cd12833
Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; A bacterial subgroup belonging to ...
 1244-1333 6.78e-03

Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; A bacterial subgroup belonging to the Escherichia coli CorA-Salmonella typhimurium ZntB_like family (EcCorA_ZntB-like) of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subgroup includes the Zn2+ transporter Salmonella typhimurium ZntB which mediates the efflux of Zn2+ (and Cd2+). Structures of the intracellular domain of Vibrio parahaemolyticus and Salmonella typhimurium ZntB form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, and Mrs2p. Natural variants such as GVN and GIN, which occur in proteins belonging to this subfamily, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.


Pssm-ID: 213367 [Multi-domain]  Cd Length: 290  Bit Score: 40.17  E-value: 6.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1244 QLHDK--QIELAMSRDEQALLQAEADGLRQEVICLKEHLSP-----------------STDSDSLRSLNERLQRELEDLk 1304
Cdd:cd12833  126 ELEDRldELEERVLEEEDEELRGELAELRRQAIALRRYLAPqrdalerlaredlpwlsDDDRLRLREAADRLTRYIEDL- 204

                         90       100
                 ....*....|....*....|....*....
gi 22024255 1305 hKSAGAESNMQQeiEELqanNQQMAERIN 1333
Cdd:cd12833  205 -DAIRERAAVLQ--EEL---TNRRAEQMN 227
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 445-675 7.29e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 7.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  445 AESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENENYLDKLRENKKSSDSQTNEAQDQQKKLQAAKDEAeskll 524
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL----- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  525 atEELLHSLRNDYKAQEEKVALLE--------DKLKTLSKENDVNVEKLHHINEQR---EAQSTDSQQKINELRAAKDEA 593
Cdd:COG3883   89 --GERARALYRSGGSVSYLDVLLGsesfsdflDRLSALSKIADADADLLEELKADKaelEAKKAELEAKLAELEALKAEL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  594 EAKLLSTEHSLNALQAALSAKEEQAASLEQSLNALKTESEHSLQDLRLHNDQLLEIVQRHQQNDWEAQLARAREELAAIQ 673
Cdd:COG3883  167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASA 246


                 ..
gi 22024255  674 SQ 675
Cdd:COG3883  247 AG 248
PRK11281 PRK11281
mechanosensitive channel MscK;
749-1048 9.37e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 40.67  E-value: 9.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   749 ATSQASLLAKEKELKASGNKLNKIKkqheQHQAKSSDQSARLEALQSELADRlshsRQVESEKEELQARVTGILEEIGTM 828
Cdd:PRK11281   28 RAASNGDLPTEADVQAQLDALNKQK----LLEAEDKLVQQDLEQTLALLDKI----DRQKEETEQLKQQLAQAPAKLRQA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   829 QAQMQQVQDSHSELEREK------RKLESRIESLQQEQ--------------VDSSAQDERTSAkleEIQSENTKLAERN 888
Cdd:PRK11281  100 QAELEALKDDNDEETRETlstlslRQLESRLAQTLDQLqnaqndlaeynsqlVSLQTQPERAQA---ALYANSQRLQQIR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   889 CLLEeqtNHLESQLQAKQDEIGKIQAklQQVLDEHSKLQNAQELMDHDhrTLQdkcDAYEKDKLLTKHTLDCLQSASEEL 968
Cdd:PRK11281  177 NLLK---GGKVGGKALRPSQRVLLQA--EQALLNAQNDLQRKSLEGNT--QLQ---DLLQKQRDYLTARIQRLEHQLQLL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   969 HRVKANLDRELKEQ--DQQLSELRERQREQEQQLKDQAERCAKLkaqnseSETQLQATIS-------NLR--EQLDAYKQ 1037
Cdd:PRK11281  247 QEAINSKRLTLSEKtvQEAQSQDEAARIQANPLVAQELEINLQL------SQRLLKATEKlntltqqNLRvkNWLDRLTQ 320

                         330
                  ....*....|.
gi 22024255  1038 TEQGIQEKLQA 1048
Cdd:PRK11281  321 SERNIKEQISV 331
PRK01156 PRK01156
chromosome segregation protein; Provisional
 157-493 9.50e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 40.66  E-value: 9.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   157 DRYHKYRCRYTDLAKKYKELERDSSKARSVLVETQDKALRRISELREQCTLEQQAKAHLE-------------EALRVEM 223
Cdd:PRK01156  339 NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKiqeidpdaikkelNEINVKL 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   224 DDMSCKMQAYQTKLQLLGENPENITAALER-SGQQL-------------------ESEQLIDLEESIGK-----SPLSTN 278
Cdd:PRK01156  419 QDISSKVSSLNQRIRALRENLDELSRNMEMlNGQSVcpvcgttlgeeksnhiinhYNEKKSRLEEKIREieievKDIDEK 498

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   279 GSSGVSDLQRLLKERDEQLKSVTEKYEAVRKQEEENVLLLAQTKQAiHTELELKDTEVRKLqeKLKQLESQRESHNN--- 355
Cdd:PRK01156  499 IVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSL--KLEDLDSKRTSWLNala 575

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   356 ---------------EVKEQFKKLQATKQEV-----------DAKLMATEHLLNTLKESYAIKEQQVVTLEAQLEAIRVE 409
Cdd:PRK01156  576 vislidietnrsrsnEIKKQLNDLESRLQEIeigfpddksyiDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNY 655

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255   410 NEQ--KVKDLQKQNEDRNTQASDSSEQLKKLQAAVQDAESQLLSKDQLLESLRSEQAAKEQQLKHLKEQLGKLKQENE-- 485
Cdd:PRK01156  656 KKQiaEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIKKai 735


                  ....*...
gi 22024255   486 NYLDKLRE 493
Cdd:PRK01156  736 GDLKRLRE 743
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
970-1345 9.59e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 9.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255  970 RVKANLDRELKEQDQQLsELRERQREQEQQLKDQAERCAKLKAQNSESETQLQATISNLREQLDAYKQTEQgiQEKLQAT 1049
Cdd:COG4717   64 RKPELNLKELKELEEEL-KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE--LEALEAE 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1050 NSSYTTQIATLEARWSAANSDVERLHEANDALQLEMEQLKIKHGQEREEVKESIAQKNRQVVELQEAMATRDRQLQEKIE 1129
Cdd:COG4717  141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQE 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1130 ASEKLAKFDEILIENEYLNKHTKQLEAE-------------LAESAELKEKLKS-----------LQCELYVLQEKAEQH 1185
Cdd:COG4717  221 ELEELEEELEQLENELEAAALEERLKEArlllliaaallalLGLGGSLLSLILTiagvlflvlglLALLFLLLAREKASL 300

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1186 AVQMAEKETQSATATAEVSELKKAIEEQAVELTRQKEHASFVTEQSDAVQKDLLQAQQQLHDKQIELAMSRDEQALLQAE 1265
Cdd:COG4717  301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAG 380

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22024255 1266 ADGLRQEVICLKEHLSPSTDSDSLRSLNERLQRELEDLKHKSAGA-ESNMQQEIEELQANNQQMAERINELETLRAGIQA 1344
Cdd:COG4717  381 VEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALdEEELEEELEELEEELEELEEELEELREELAELEA 460


                 .
gi 22024255 1345 Q 1345
Cdd:COG4717  461 E 461
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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