NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

806-1045

1.05e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.13 E-value: 1.05e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  806 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD-RLQSELRQ 883
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  884 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 963
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  964 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1043
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 386767625 1044 EL 1045
Cdd:COG1196   464 LL 465

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

762-1130

1.45e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 1.45e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   762 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 841
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   842 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 912
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   913 RMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnaiRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 992
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE---IEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   993 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1069
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767625  1070 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1130
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

733-1029

4.95e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.07 E-value: 4.95e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   733 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 802
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   803 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 875
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   876 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 955
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767625   956 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1029
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

677-1051

1.58e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.93 E-value: 1.58e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  677 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 755
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  756 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 835
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  836 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 915
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  916 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 995
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625  996 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1051
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

679-920

6.44e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 6.44e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  679 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 758
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  759 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 838
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  839 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 918
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 386767625  919 EK 920
Cdd:COG4942   241 ER 242

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

645-927

2.08e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.60 E-value: 2.08e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   645 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 720
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   721 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 794
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   795 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 874
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767625   875 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 927
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

978-1129

7.16e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.16e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  978 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1055
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1056 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1125
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 386767625 1126 QQRK 1129
Cdd:COG3206   338 QLEA 341

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

805-917

1.63e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 44.88 E-value: 1.63e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  805 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 879
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767625  880 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 917
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

645-936

2.32e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 2.32e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   645 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 715
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   716 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 793
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   794 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 871
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625   872 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 936
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

growth_prot_Scy

NF041483

polarized growth protein Scy;

729-1041

3.45e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 44.82 E-value: 3.45e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  729 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 795
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  796 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 875
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  876 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 955
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  956 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1023
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 386767625 1024 ------LAEADAQVRNSQAEVKQL 1041
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

923-1103

9.47e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.47e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  923 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 1000
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1001 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1066
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767625 1067 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1103
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

PRK11281

mechanosensitive channel MscK;

975-1129

6.66e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 6.66e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  975 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLqlelshsKKMCGD 1054
Cdd:PRK11281   41 VQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQ-KEETEQLKQQLAQAPAKLRQAQAELEAL-------KDDNDE 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1055 IIMER------DRLRDNLN------ADIQSELGVLN----------ERHKQEMDQLQKRVhQTIQRQEETIEILKGDNDA 1112
Cdd:PRK11281  113 ETRETlstlslRQLESRLAqtldqlQNAQNDLAEYNsqlvslqtqpERAQAALYANSQRL-QQIRNLLKGGKVGGKALRP 191

                         170       180
                  ....*....|....*....|..
gi 386767625 1113 LRQQCLK-----LNAVIRQQRK 1129
Cdd:PRK11281  192 SQRVLLQaeqalLNAQNDLQRK 213

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

859-934

9.32e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 37.95 E-value: 9.32e-03

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625    859 QAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQA 934
Cdd:smart00935   12 ESPAGKAAQKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK 87

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

806-1045

1.05e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.13 E-value: 1.05e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  806 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD-RLQSELRQ 883
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDiARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  884 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 963
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  964 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1043
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 386767625 1044 EL 1045
Cdd:COG1196   464 LL 465

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

677-1009

1.33e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 1.33e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  677 EKQ-KSLRAEKSTA--AAKLRDQKKHYEEVVTRHQgfIEQLLKDKGSLCEKVAALTRRLESQnQAWEHRLETELARTKEt 753
Cdd:COG1196   199 ERQlEPLERQAEKAerYRELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEEL-EAELAELEAELEELRL- 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  754 tmageKIRRERwvrentKKIKELtvKGLEAEINKmncdhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDR 833
Cdd:COG1196   275 -----ELEELE------LELEEA--QAEEYELLA-----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  834 EAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQER 913
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  914 MAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMN 993
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLL 494

                         330
                  ....*....|....*.
gi 386767625  994 RLKEKYEKDLVLAESV 1009
Cdd:COG1196   495 LLLEAEADYEGFLEGV 510

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

762-1130

1.45e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 1.45e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   762 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 841
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   842 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 912
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   913 RMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnaiRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 992
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE---IEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   993 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1069
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767625  1070 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1130
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

673-1047

1.87e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 1.87e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  673 QLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKE 752
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  753 -TTMAGEKIRRERWVRENTKKIKELTVKGLEAEinkmncDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREScAQ 831
Cdd:COG1196   297 lARLEQDIARLEERRRELEERLEELEEELAELE------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL-LE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  832 DREAIIEKERTaiRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENehQARRQEALREQEQELEQAKFEMQ 911
Cdd:COG1196   370 AEAELAEAEEE--LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE--LEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  912 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKenairqhyRAERDRQLDELVVRMEADALQHKEEHELK 991
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--------AAARLLLLLEAEADYEGFLEGVKAALLLA 517

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625  992 MNRLKEKYEKDLVLAESVEkslrEKYAETRGKLAEADAQVRNSQAEVKQLQLELSH 1047
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

797-1128

3.85e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.74 E-value: 3.85e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  797 TELKRTHQMQLLDALEEARTKHEQIETSIREscaqdreaiiekeRTAIRERFERQLEEEQRTQAEQRQKLTEEfAAERDR 876
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEE-------------LEAELEELEAELAELEAELEELRLELEEL-ELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  877 LQSELRQRENEHQA--RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEK 954
Cdd:COG1196   286 AQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  955 ENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMNRLKEkyekdlvlAESVEKSLREKYAETRGKLAEADAQVRNS 1034
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEE-LLEALRAAAELAAQLEELEE--------AEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1035 QAEVKQLQLELSHSKKmcgdiimERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRvhQTIQRQEETIEILKGDNDALR 1114
Cdd:COG1196   437 EEEEEEALEEAAEEEA-------ELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFL 507

                         330
                  ....*....|....
gi 386767625 1115 QQCLKLNAVIRQQR 1128
Cdd:COG1196   508 EGVKAALLLAGLRG 521

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

733-1029

4.95e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.07 E-value: 4.95e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   733 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 802
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   803 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 875
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   876 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 955
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767625   956 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1029
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

677-1051

1.58e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.93 E-value: 1.58e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  677 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 755
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  756 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 835
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  836 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 915
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  916 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 995
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625  996 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1051
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

mukB

chromosome partition protein MukB;

794-1129

2.94e-10

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 64.98 E-value: 2.94e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  794 REVTELKRTHQmqlldALEEARTKHEQIetsireSCAQDREAIIEKERTAIRERfERQLE--EEQRTQAEQRQKLTEEFA 871
Cdd:PRK04863  807 FDVQKLQRLHQ-----AFSRFIGSHLAV------AFEADPEAELRQLNRRRVEL-ERALAdhESQEQQQRSQLEQAKEGL 874

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  872 AERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQermakqeeKYQNRVNTIEQQY------QADFELWKTEHEn 945
Cdd:PRK04863  875 SALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQ--------QHGNALAQLEPIVsvlqsdPEQFEQLKQDYQ- 945

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  946 ktklaQAEKenaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaesveksLREKYAETRGKLA 1025
Cdd:PRK04863  946 -----QAQQ----TQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEK--------------LRQRLEQAEQERT 1002

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1026 EADAQVRNSQAEVKQlqlelshSKKMCGDIIMERDRLRDNLNADIQ--SELGV-----LNERHKQEMDQLQKRVHQTIQR 1098
Cdd:PRK04863 1003 RAREQLRQAQAQLAQ-------YNQVLASLKSSYDAKRQMLQELKQelQDLGVpadsgAEERARARRDELHARLSANRSR 1075

                         330       340       350
                  ....*....|....*....|....*....|....
gi 386767625 1099 Q---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1129
Cdd:PRK04863 1076 RnqlEKQLTFCEAEMDNLTKKLRKLERDYHEMRE 1109

PTZ00121

MAEBL; Provisional

656-1090

3.22e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.78 E-value: 3.22e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  656 RANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV--VTRHQGFIEQLLKDKGSLCEKVAALTRRLE 733
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKkkADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  734 SQNQAWEHRLETELARTKETTMAGEKIRRERwvrENTKKIKELTVKGLE---AEINKMNCDHQREVTELKRTHQMQLLDA 810
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKA---EEAKKAEEAKKKAEEakkADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  811 lEEARTKHEQIETSIRESCAQD-REAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 889
Cdd:PTZ00121 1500 -DEAKKAAEAKKKADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNM 1578

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  890 A-RRQEALREQEQ----------------ELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF--------ELWKTEHE 944
Cdd:PTZ00121 1579 AlRKAEEAKKAEEarieevmklyeeekkmKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEaeekkkaeELKKAEEE 1658

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  945 NKTKLAQaEKENAIRQHYRAERDRQLDElVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKL 1024
Cdd:PTZ00121 1659 NKIKAAE-EAKKAEEDKKKAEEAKKAEE-DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK 1736

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625 1025 AEADAQVRNSQaEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQLQK 1090
Cdd:PTZ00121 1737 KEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

831-1113

1.46e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.39 E-value: 1.46e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   831 QDREAIIEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAAERDRLQSElRQRENEHQARRQEALREQEQELEQAKF 908
Cdd:TIGR02169  680 RERLEGLKRELSSLQSELRRieNRLDELSQELSDASRKIGEIEKEIEQLEQE-EEKLKERLEELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   909 EMQE---RMAKQEE---KYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDElvvRMEADAL 982
Cdd:TIGR02169  759 ELKEleaRIEELEEdlhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK---EYLEKEI 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   983 QHKEEhelKMNRLKEKyekdlvlaesvEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRL 1062
Cdd:TIGR02169  836 QELQE---QRIDLKEQ-----------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK-------ERDEL 894

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 386767625  1063 RDNLNAdIQSELGVLNErhkqEMDQLQKRVHQtiqrQEETIEILKGDNDAL 1113
Cdd:TIGR02169  895 EAQLRE-LERKIEELEA----QIEKKRKRLSE----LKAKLEALEEELSEI 936

PTZ00121

MAEBL; Provisional

667-1026

1.80e-09

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.47 E-value: 1.80e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  667 SKEHVFQLRGEKQKSL-----RAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLceKVAALTRRLESQNQAWEH 741
Cdd:PTZ00121 1062 AKAHVGQDEGLKPSYKdfdfdAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAK--KKAEDARKAEEARKAEDA 1139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  742 R-----------------------LETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTE 798
Cdd:PTZ00121 1140 RkaeearkaedakrveiarkaedaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK 1219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  799 LKRTHQMQLLDALEEARTKHEqietsirESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQ 878
Cdd:PTZ00121 1220 AEDAKKAEAVKKAEEAKKDAE-------EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  879 SELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNrvntIEQQYQADfELWKTEHENKTKLAQAEKENAI 958
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAA-EAAKAEAEAAADEAEAAEEKAE 1367

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767625  959 RQHYRAERDRQldelvvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE-KYAETRGKLAE 1026
Cdd:PTZ00121 1368 AAEKKKEEAKK--------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAkKKADEAKKKAE 1428

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

762-1040

5.79e-09

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 59.16 E-value: 5.79e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   762 RERWVRENtKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETsiRESCAQDREAIIEKER 841
Cdd:pfam13868   24 RDAQIAEK-KRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEE--REQKRQEEYEEKLQER 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   842 TAIRERFERQLEEEQRTQAEQRQKLTE------EFAAERDRLQSELRQRENE----------HQARRQEALREQEQELEQ 905
Cdd:pfam13868  101 EQMDEIVERIQEEDQAEAEEKLEKQRQlreeidEFNEEQAEWKELEKEEEREederileylkEKAEREEEREAEREEIEE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   906 AKFEMQERMAKQEEKYQNRvntIEQQYQADFELWKTEHENKTK---LAQAEKENAIRQHYRAERDRQLDELVVRMEADAL 982
Cdd:pfam13868  181 EKEREIARLRAQQEKAQDE---KAERDELRAKLYQEEQERKERqkeREEAEKKARQRQELQQAREEQIELKERRLAEEAE 257

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625   983 QHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQ 1040
Cdd:pfam13868  258 REEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELE 315

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

832-1129

7.92e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 60.35 E-value: 7.92e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  832 DREAIIEKERTAIRErFERQLEEEQRTQAEQRQKLTEefAAER----DRLQSELRQRENEHQARRQEALREQEQELEQAK 907
Cdd:COG3096   833 DPEAELAALRQRRSE-LERELAQHRAQEQQLRQQLDQ--LKEQlqllNKLLPQANLLADETLADRLEELREELDAAQEAQ 909

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  908 FEMQeRMAKQEEKYQNRVNTIeQQYQADFELWKTEHENktklAQAEKENAIRQHYraerdrQLDELVVRMEADALQHKEE 987
Cdd:COG3096   910 AFIQ-QHGKALAQLEPLVAVL-QSDPEQFEQLQADYLQ----AKEQQRRLKQQIF------ALSEVVQRRPHFSYEDAVG 977

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  988 HELKMNRLKEKYEKDLVLAESvekslrekyaetrgKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRLRDNLN 1067
Cdd:COG3096   978 LLGENSDLNEKLRARLEQAEE--------------ARREAREQLRQAQAQYSQYNQVLASLKS-------SRDAKQQTLQ 1036

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767625 1068 ADIQ--SELGVLN-----ERHKQEMDQLQKRVHQTIQRQ---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1129
Cdd:COG3096  1037 ELEQelEELGVQAdaeaeERARIRRDELHEELSQNRSRRsqlEKQLTRCEAEMDSLQKRLRKAERDYKQERE 1108

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

691-1097

1.29e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.01 E-value: 1.29e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  691 AKLRDQKKHYEEVVTRHQGfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKettmAGEKIRRERWVRENT 770
Cdd:COG4717    81 KEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE----LAELPERLEELEERL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  771 KKIKEL--TVKGLEAEINKmncdHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscAQDREAIIEKERTAIRERF 848
Cdd:COG4717   156 EELRELeeELEELEAELAE----LQEELEELLEQLSLATEEELQDLAEELEELQQRLAE--LEEELEEAQEELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  849 ErQLEEEQRTQAEQRQKLTEE-----------FAAERDRLQSELRQREN-------------EHQARRQEALREQEQELE 904
Cdd:COG4717   230 E-QLENELEAAALEERLKEARlllliaaallaLLGLGGSLLSLILTIAGvlflvlgllallfLLLAREKASLGKEAEELQ 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  905 QAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEN--AIRQHYRAERDRQLDELVVRMEAD-- 980
Cdd:COG4717   309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeLQLEELEQEIAALLAEAGVEDEEElr 388

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  981 --ALQHKEEHELK--MNRLKEKYEKDL-----VLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHskkm 1051
Cdd:COG4717   389 aaLEQAEEYQELKeeLEELEEQLEELLgeleeLLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ---- 464

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 386767625 1052 cgdiiMERDRLRDNLNADIQSELGVLNERHKQE---------MDQLQKRVHQTIQ 1097
Cdd:COG4717   465 -----LEEDGELAELLQELEELKAELRELAEEWaalklalelLEEAREEYREERL 514

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

843-1045

2.46e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 2.46e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHqarrqEALREQEQELEQAKfEMQERMAKQEEKYQ 922
Cdd:COG4717    42 FIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKE-----EEYAELQEELEELE-EELEELEAELEELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  923 NRVNTIEQQYQAdFELWKTEHENKTKLAQAEKE-NAIRQHY--RAERDRQLDELvvrmEADALQHKEEHELKMNRLKEKY 999
Cdd:COG4717   116 EELEKLEKLLQL-LPLYQELEALEAELAELPERlEELEERLeeLRELEEELEEL----EAELAELQEELEELLEQLSLAT 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 386767625 1000 EKDLvlaesveKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1045
Cdd:COG4717   191 EEEL-------QDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

823-1129

3.32e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 3.32e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   823 TSIRESCAQDREAIIEkeRTAIRERFERQLEEEQRTQAEQRQKLteefaAERDRLQSELRQRENEHQARRQEALREQEQE 902
Cdd:TIGR02169  145 TDFISMSPVERRKIID--EIAGVAEFDRKKEKALEELEEVEENI-----ERLDLIIDEKRQQLERLRREREKAERYQALL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   903 LEQAKFEMQER------MAKQEEKYQNRVNTIEQQyQADF-----ELWKTEHENKTKLAQAEKE---------NAIR--- 959
Cdd:TIGR02169  218 KEKREYEGYELlkekeaLERQKEAIERQLASLEEE-LEKLteeisELEKRLEEIEQLLEELNKKikdlgeeeqLRVKeki 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   960 ---QHYRAERDRQLDELVVRME-ADALQHKEEHEL-----KMNRLKEKYEKDLVLAESVE---KSLREKYAETRGKLAEA 1027
Cdd:TIGR02169  297 gelEAEIASLERSIAEKERELEdAEERLAKLEAEIdkllaEIEELEREIEEERKRRDKLTeeyAELKEELEDLRAELEEV 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1028 DAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLN------ADIQSELGVLNERHKQ---EMDQLQKRVHQTIQR 1098
Cdd:TIGR02169  377 DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQrlseelADLNAAIAGIEAKINEleeEKEDKALEIKKQEWK 456

                          330       340       350
                   ....*....|....*....|....*....|.
gi 386767625  1099 QEETIEILKGDNDALRQQCLKLNAVIRQQRK 1129
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSK 487

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

652-988

3.88e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 58.04 E-value: 3.88e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  652 ALSLRANELANAIHMSKEHvfQLRGEKQKSLRAEKSTAAAklrdqkkHYEEVVT--RHQGFIEQLLKDkgslcekVAALT 729
Cdd:COG3096   297 ARRQLAEEQYRLVEMAREL--EELSARESDLEQDYQAASD-------HLNLVQTalRQQEKIERYQED-------LEELT 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  730 RRLESQNQAWEHRLEtELARTKETTMAGEKirrerwvrentkkikelTVKGLEAEInkmnCDHQREVTELK-RTHQ-MQL 807
Cdd:COG3096   361 ERLEEQEEVVEEAAE-QLAEAEARLEAAEE-----------------EVDSLKSQL----ADYQQALDVQQtRAIQyQQA 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  808 LDALEEARTKHEQIETSIrESCAQDREAIIEKERTAIRERFE-RQ---LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ 883
Cdd:COG3096   419 VQALEKARALCGLPDLTP-ENAEDYLAAFRAKEQQATEEVLElEQklsVADAARRQFEKAYELVCKIAGEVERSQAWQTA 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  884 RENEHQARRQEALREQEQELEQAKFEMQERMAKQE--EKYQNRVN-TIEQQYQA--DFELWKTEHENKTKLAQAEKENAI 958
Cdd:COG3096   498 RELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQnaERLLEEFCqRIGQQLDAaeELEELLAELEAQLEELEEQAAEAV 577

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 386767625  959 RQhyRAERDRQLDELVVRME------------ADALQHKEEH 988
Cdd:COG3096   578 EQ--RSELRQQLEQLRARIKelaarapawlaaQDALERLREQ 617

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

806-1115

4.16e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.44 E-value: 4.16e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   806 QLLDALEEARTKHEQIETSIRESCAQDREAIiEKERTAIRERFERQLEE-EQRTQAE---------QRQKLTEEFAAERD 875
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQ-EKEEKAREVERRRKLEEaEKARQAEmdrqaaiyaEQERMAMERERELE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   876 RLQSELRQRENEhQARRQEALREQEQ--ELEQAKFEMQER--MAKQEEKYQNRVNTIEQQYQADFELWKTEHENktklAQ 951
Cdd:pfam17380  352 RIRQEERKRELE-RIRQEEIAMEISRmrELERLQMERQQKneRVRQELEAARKVKILEEERQRKIQQQKVEMEQ----IR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   952 AEKENAIRQHYR---AERDRQLDElvVRMEadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEAD 1028
Cdd:pfam17380  427 AEQEEARQREVRrleEERAREMER--VRLE----EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1029 AQVRnsqaevKQLQLELSHSKKMCGDIIMErdrlRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEET---IEI 1105
Cdd:pfam17380  501 LEER------KQAMIEEERKRKLLEKEMEE----RQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEErsrLEA 570

                          330
                   ....*....|
gi 386767625  1106 LKGDNDALRQ 1115
Cdd:pfam17380  571 MEREREMMRQ 580

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

830-1130

4.47e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 57.64 E-value: 4.47e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  830 AQDREAIIE--------KERtaiRERFERQLEEeqrtqAEQR----QKLTEEFAAERDRLQselRQREnehQARRQEALR 897
Cdd:COG1196   154 PEERRAIIEeaagiskyKER---KEEAERKLEA-----TEENlerlEDILGELERQLEPLE---RQAE---KAERYRELK 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  898 EqeqELEQAKFEM--------QERMAKQEEKYQNRVNTIEQQyQADFELWKTEHEnKTKLAQAEKENAIRQhyRAERDRQ 969
Cdd:COG1196   220 E---ELKELEAELlllklrelEAELEELEAELEELEAELEEL-EAELAELEAELE-ELRLELEELELELEE--AQAEEYE 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  970 LDELVVRMEADaLQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK 1049
Cdd:COG1196   293 LLAELARLEQD-IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1050 KMCGDIIMERDRLRDNLNADIQSELGVLNERhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRK 1129
Cdd:COG1196   372 AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449


                  .
gi 386767625 1130 D 1130
Cdd:COG1196   450 E 450

PTZ00121

MAEBL; Provisional

677-1101

2.09e-07

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.53 E-value: 2.09e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTrhqgfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMA 756
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  757 GEKIRRERWVRENTKKikeltvkglEAEINKMNCDHQREVTELKRThqmqlldaLEEARTKHEQIETSIRESCAQDrEAI 836
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKK---------KADAAKKKAEEKKKADEAKKK--------AEEDKKKADELKKAAAAKKKAD-EAK 1424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  837 IEKERTAIRERFERQLEEEQRTQaEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQE--QELEQAKFEMQE-R 913
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEakKKAEEAKKKADEaK 1503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  914 MAKQEEKYQNRVNTIEQQYQADfELWKTEHENKtklaqAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMN 993
Cdd:PTZ00121 1504 KAAEAKKKADEAKKAEEAKKAD-EAKKAEEAKK-----ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  994 RLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSE 1073
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657

                         410       420
                  ....*....|....*....|....*...
gi 386767625 1074 LGVLNERHKQEMDQLQKRVHQTIQRQEE 1101
Cdd:PTZ00121 1658 ENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

677-934

2.18e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 2.18e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRhQGFIEQLLKDKGSLCEKVAALTRRLESQNQAwEHRLETELARTKEttma 756
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQEL-EEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRE---- 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   757 gekiRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscaqdREAI 836
Cdd:TIGR02168  310 ----RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE-----LEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   837 IEKERTAIRERfERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQ---ER 913
Cdd:TIGR02168  381 LETLRSKVAQL-ELQIASLNNEIERLEARL-ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQeelER 458

                          250       260
                   ....*....|....*....|.
gi 386767625   914 MAKQEEKYQNRVNTIEQQYQA 934
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDA 479

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

689-1130

5.10e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 5.10e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  689 AAAKLRDQKKHYEEVVTRHQGFIEQLLKdkgslcekvAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRE 768
Cdd:COG4913   243 ALEDAREQIELLEPIRELAERYAAARER---------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  769 NTKKIKELTVKGLEAEINKMNCDHQReVTELKRthqmqLLDALEEARTKHEQIETSIRESCAQdreaiIEKERTAIRERF 848
Cdd:COG4913   314 LEARLDALREELDELEAQIRGNGGDR-LEQLER-----EIERLERELEERERRRARLEALLAA-----LGLPLPASAEEF 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  849 ERQLEEEQRtQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQE--ALREQ----EQELEQAKFEMQER--------- 913
Cdd:COG4913   383 AALRAEAAA-LLEALEEELEALEEALAEAEAALRDLRRELRELEAEiaSLERRksniPARLLALRDALAEAlgldeaelp 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  914 -------MAKQEEKYQNRVNT----------IEQQYQADFelwkTEHENKTKLAQaekenaiRQHYRAERDRQLDELVVR 976
Cdd:COG4913   462 fvgelieVRPEEERWRGAIERvlggfaltllVPPEHYAAA----LRWVNRLHLRG-------RLVYERVRTGLPDPERPR 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  977 MEADALQHK---EEHELKmNRLKEKYEK--DLVLAESVEKSLREKYAETR-------GKLAEADAQVRNS---------- 1034
Cdd:COG4913   531 LDPDSLAGKldfKPHPFR-AWLEAELGRrfDYVCVDSPEELRRHPRAITRagqvkgnGTRHEKDDRRRIRsryvlgfdnr 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1035 ------QAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAdiqseLGVLNERHKQEMDQLQkrVHQTIQRQEETIEILKG 1108
Cdd:COG4913   610 aklaalEAELAELEEELAEAEERLEALEAELDALQERREA-----LQRLAEYSWDEIDVAS--AEREIAELEAELERLDA 682

                         490       500
                  ....*....|....*....|....*
gi 386767625 1109 DND---ALRQQCLKLNAVIRQQRKD 1130
Cdd:COG4913   683 SSDdlaALEEQLEELEAELEELEEE 707

mukB

chromosome partition protein MukB;

652-998

5.24e-07

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 54.19 E-value: 5.24e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  652 ALSLRAnELANA---IHMSKEHVFQLRGEKQKSLRAEKSTAAAkLRDQKKHYEEVVT--RHQGFIEQLLKDkgslcekVA 726
Cdd:PRK04863  288 ALELRR-ELYTSrrqLAAEQYRLVEMARELAELNEAESDLEQD-YQAASDHLNLVQTalRQQEKIERYQAD-------LE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  727 ALTRRLESQNQAWEHRLETELARTKETTMAGEKIRR---------ERWVRENTKKIK------------------ELTVK 779
Cdd:PRK04863  359 ELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDElksqladyqQALDVQQTRAIQyqqavqalerakqlcglpDLTAD 438

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  780 GLEAEINKMNcDHQREVTElKRTHQMQLLDALEEARTKHEQIETSI----------------RESCAQDREAIIEKERT- 842
Cdd:PRK04863  439 NAEDWLEEFQ-AKEQEATE-ELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsrseawdvaRELLRRLREQRHLAEQLq 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERF---ERQLEEEQR-----TQAEQRQKLTEEFAAERDRLQSELRQRENEHQArRQEALREQ----EQELEQAKFEM 910
Cdd:PRK04863  517 QLRMRLselEQRLRQQQRaerllAEFCKRLGKNLDDEDELEQLQEELEARLESLSE-SVSEARERrmalRQQLEQLQARI 595

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  911 QERMAKQEE--KYQNRVNTIEQQYQADFElwKTEHENKTKLAQAEKENAIRQHYR--AERDRQLDElvvrmEADALQHKE 986
Cdd:PRK04863  596 QRLAARAPAwlAAQDALARLREQSGEEFE--DSQDVTEYMQQLLERERELTVERDelAARKQALDE-----EIERLSQPG 668

                         410
                  ....*....|...
gi 386767625  987 EHEL-KMNRLKEK 998
Cdd:PRK04863  669 GSEDpRLNALAER 681

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

723-1050

5.48e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.92 E-value: 5.48e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   723 EKVAALTRRLEsQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKEL--TVKGLEAEINKMNcdhqREVTELK 800
Cdd:TIGR02169  211 ERYQALLKEKR-EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELekRLEEIEQLLEELN----KKIKDLG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   801 RTHQMQLLDALEEARTKHEQIETSIRESC-----AQDREAIIEKERTAIRERFErQLEEEQRTQAeqrqklteefaAERD 875
Cdd:TIGR02169  286 EEEQLRVKEKIGELEAEIASLERSIAEKEreledAEERLAKLEAEIDKLLAEIE-ELEREIEEER-----------KRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   876 RLQSELRQRENEHQARRQEAlreqeqeleqakfemqermakqeekyqnrvntieQQYQADFELWKTEHenktKLAQAEKE 955
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAEL----------------------------------EEVDKEFAETRDEL----KDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   956 NAIRQHY--RAERDRQLDELvVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRN 1033
Cdd:TIGR02169  396 KLKREINelKRELDRLQEEL-QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWKLEQLAADLSKYEQELYD 473

                          330
                   ....*....|....*..
gi 386767625  1034 SQAEVKQLQLELSHSKK 1050
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQR 490

PRK12704

phosphodiesterase; Provisional

799-923

7.26e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 53.24 E-value: 7.26e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  799 LKRTHQMQLLDALEEARtkhEQIETSIRESCAQDREAIIE--KERTAIRERFERQLEEEQR--TQAEQRQKLTEEFAaer 874
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAK---RILEEAKKEAEAIKKEALLEakEEIHKLRNEFEKELRERRNelQKLEKRLLQKEENL--- 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 386767625  875 DRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEEKYQN 923
Cdd:PRK12704   99 DRKLELLEKREEELEKKEKE-LEQKQQELEKKEEELEELIEEQLQELER 146

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

723-973

8.56e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 8.56e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  723 EKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKIRRERWVrentkkikELTVKGLEAEINkmncDHQREVTELKRT 802
Cdd:COG4913   617 AELAELEEELAEAEERLE-ALEAELDALQERREALQRLAEYSWD--------EIDVASAEREIA----ELEAELERLDAS 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  803 HQMqlLDALEE----ARTKHEQIETSIREscAQDREAIIEKERTAIRERFER---QLEE-EQRTQAEQRQKLTEEFAAE- 873
Cdd:COG4913   684 SDD--LAALEEqleeLEAELEELEEELDE--LKGEIGRLEKELEQAEEELDElqdRLEAaEDLARLELRALLEERFAAAl 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  874 RDRLQSELRQRENEHQARRQEALREQEQELEQA--------KFEMQERMAKQE--EKYQNRVNTIEQ----QYQADFElw 939
Cdd:COG4913   760 GDAVERELRENLEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLEslPEYLALLDRLEEdglpEYEERFK-- 837

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 386767625  940 ktehENKTKLAQAEKENAIRQHYRAERD--RQLDEL 973
Cdd:COG4913   838 ----ELLNENSIEFVADLLSKLRRAIREikERIDPL 869

PRK02224

DNA double-strand break repair Rad50 ATPase;

771-1130

1.08e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.12 E-value: 1.08e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  771 KKIKEL--TVKGLEAEINKM-----NCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiEKERTA 843
Cdd:PRK02224  199 KEEKDLheRLNGLESELAELdeeieRYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAET--EREREE 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  844 IRERFerqleeeqRTQAEQRQKLTEEFAAERDRlqSELRQRENEHQARRQEALREQEQELEQAKFEM---QERMAKQEEK 920
Cdd:PRK02224  277 LAEEV--------RDLRERLEELEEERDDLLAE--AGLDDADAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEAES 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  921 YQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEaDAlqhkeehelkmnrlkekyE 1000
Cdd:PRK02224  347 LREDADDLEERAE---ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG-DA------------------P 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1001 KDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK-KMCG---------DIIMERDRLRDNLNA-- 1068
Cdd:PRK02224  405 VDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcPECGqpvegsphvETIEEDRERVEELEAel 484

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767625 1069 -DIQSELGVLNERHKQ---------EMDQLQ---KRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRKD 1130
Cdd:PRK02224  485 eDLEEEVEEVEERLERaedlveaedRIERLEerrEDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA 559

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

793-1122

1.09e-06

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 1.09e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   793 QREVTELK----RTHQMQLLDALEEARTKHEQIEtsIRESCAQD----REAIIEKERTAIRERFErQLEEEQRTQAEQRQ 864
Cdd:TIGR02168  173 RRKETERKlertRENLDRLEDILNELERQLKSLE--RQAEKAERykelKAELRELELALLVLRLE-ELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   865 KLTEEFAAERDRLQ-------------SELRQRENEHQARRQEALREQEqELEQAKFEMQERMAKQEEKYQNRVNTIEQQ 931
Cdd:TIGR02168  250 EAEEELEELTAELQeleekleelrlevSELEEEIEELQKELYALANEIS-RLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   932 YQADFELWKTEHENKTKLAQAEKEnairqhyraerdrqldelvvrMEADALQHKEEHELKMNrLKEKYEKDLVLAEsvek 1011
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEE---------------------LESLEAELEELEAELEE-LESRLEELEEQLE---- 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1012 SLREKYAETRGKLAEADAQVRNSQAEVKQLQLELshsKKMCGDIIMERDRLRDNLNADIQSELgvlnERHKQEMDQLQKR 1091
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAELKELQAEL----EELEEELEELQEE 455

                          330       340       350
                   ....*....|....*....|....*....|....
gi 386767625  1092 VHQTIQR---QEETIEILKGDNDALRQQCLKLNA 1122
Cdd:TIGR02168  456 LERLEEAleeLREELEEAEQALDAAERELAQLQA 489

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

793-973

1.17e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 1.17e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  793 QREVTELKRTHQmQLLDA------LEEARTKHEQIETSIREscAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKL 866
Cdd:COG4913   231 VEHFDDLERAHE-ALEDAreqielLEPIRELAERYAAARER--LAELEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  867 TeefaAERDRLQS---ELRQRENEHQARRQEA----LREQEQELEQAKFEMQERmAKQEEKYQNRVNTIEQQY---QADF 936
Cdd:COG4913   308 E----AELERLEArldALREELDELEAQIRGNggdrLEQLEREIERLERELEER-ERRRARLEALLAALGLPLpasAEEF 382

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767625  937 -ELWKTEHENKTKLAQAEK--ENAIRQHYRAERD--RQLDEL 973
Cdd:COG4913   383 aALRAEAAALLEALEEELEalEEALAEAEAALRDlrRELREL 424

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

846-1045

1.41e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 52.20 E-value: 1.41e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   846 ERFERQLEEEQRTQAEQRQKLteEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRV 925
Cdd:pfam07888   30 ELLQNRLEECLQERAELLQAQ--EAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   926 NTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnrLKEKYEKDLVL 1005
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEA-----ERKQLQAKLQQ 182

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 386767625  1006 AESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1045
Cdd:pfam07888  183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKL 222

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

830-983

1.72e-06

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 51.80 E-value: 1.72e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  830 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQeqelEQAKfe 909
Cdd:COG2268   188 ALGRRKIAEIIRDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERREA----ETAR-- 261

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767625  910 mqermAKQEEKYqnRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQ-----HYRAERDRQLDELVVRMEADALQ 983
Cdd:COG2268   262 -----AEAEAAY--EIAEANAEREVQRQLEIAEREREIELQEKEAEREEAEleadvRKPAEAEKQAAEAEAEAEAEAIR 333

PRK02224

DNA double-strand break repair Rad50 ATPase;

808-1080

2.58e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.96 E-value: 2.58e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  808 LDALEE-------ARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEqrqklTEEFAAERDRLQS- 879
Cdd:PRK02224  161 LGKLEEyrerasdARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEE-----IERYEEQREQAREt 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  880 --ELRQRENEHQARRQEAlreqeQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwktEHENKTKLAQAEKENA 957
Cdd:PRK02224  236 rdEADEVLEEHEERREEL-----ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL---EEERDDLLAEAGLDDA 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  958 ------IRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnRLKEKYEKdlvlAESVEKSLREKYAETRGKLAEADAQV 1031
Cdd:PRK02224  308 daeaveARREELEDRDEELRDRLEECRVAAQAHNEEAE----SLREDADD----LEERAEELREEAAELESELEEAREAV 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 386767625 1032 RNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDnLNADIQSELGVLNER 1080
Cdd:PRK02224  380 EDRREEIEELEEEIEELRERFGDAPVDLGNAED-FLEELREERDELRER 427

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

641-1112

2.76e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 51.76 E-value: 2.76e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   641 LPNHQLARRVIALSLRANELANAIHMSKEHVFQLRGEKqKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGS 720
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLH-FGYKSDETLIASRQ-------EERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   721 LCEKVAALTRRLESQNQAWEHRlETELARTKETTMAGEKIRRERWVRE--------NTKKIKELTVKGLEAEINKMNCDH 792
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKD-RSELEALEDQHGAFLDADIETAAADqeqlpswqSELENLEERLKALTGKHQDVTAKY 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   793 QRE--------VTELKRTHQMqlLDALEEARTK--------HEQIETSIRESC-AQDREAIIEKERTAIRERFER----- 850
Cdd:pfam12128  378 NRRrskikeqnNRDIAGIKDK--LAKIREARDRqlavaeddLQALESELREQLeAGKLEFNEEEYRLKSRLGELKlrlnq 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   851 -QLEEEQRTQAEQ--------RQKLTEEFaAERDRLQSELRQreneHQARRQEALREQEQElEQAKFEMQERMAKQEEKY 921
Cdd:pfam12128  456 aTATPELLLQLENfderieraREEQEAAN-AEVERLQSELRQ----ARKRRDQASEALRQA-SRRLEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   922 QNRVNTIEQQYQADFELWKtehENKTKLAQAEKENAIRQHYRAERDRQLDELV---VRMEADALQHKE--EHELKMNRLK 996
Cdd:pfam12128  530 FPQAGTLLHFLRKEAPDWE---QSIGKVISPELLHRTDLDPEVWDGSVGGELNlygVKLDLKRIDVPEwaASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   997 EKYEKDLVLAESVEKSLREKYAETRGKLAEADAQ-------VRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1069
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREetfartaLKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 386767625  1070 IQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDA 1112
Cdd:pfam12128  687 LEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA 729

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

882-1122

4.52e-06

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 4.52e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   882 RQRENEHQARRQE--ALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIR 959
Cdd:TIGR02168  666 AKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   960 QHYRAERDRQLDELVVRME------ADALQHKEEHELKMNRLKEKYEKDLVLAesveKSLREKYAETRGKLAEADAQVRN 1033
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEeleerlEEAEEELAEAEAEIEELEAQIEQLKEEL----KALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1034 SQAEVKQLQLELSHSKKMCGDIIMERDRLRDNL--NADIQSELGVLNERHKQEMDQLQKRVHQTIQR----------QEE 1101
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIesLAAEIEELEELIEELESELEALLNERASLEEAlallrseleeLSE 901

                          250       260
                   ....*....|....*....|.
gi 386767625  1102 TIEILKGDNDALRQQCLKLNA 1122
Cdd:TIGR02168  902 ELRELESKRSELRRELEELRE 922

PRK12704

phosphodiesterase; Provisional

833-1006

4.89e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.55 E-value: 4.89e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  833 REAIIEKERTAIRERFERQLEEEQR-TQAEQRQKLTE---EFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQakf 908
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKeAEAIKKEALLEakeEIHKLRNEFEKELRERRNELQ-KLEKRLLQKEENLDR--- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  909 eMQERMAKQEEKYQNRVNTIEQQYQaDFELWKTEHENKTKLAQAEKENaIRQHYRAE-RDRQLDELVVRMEADALQH-KE 986
Cdd:PRK12704  101 -KLELLEKREEELEKKEKELEQKQQ-ELEKKEEELEELIEEQLQELER-ISGLTAEEaKEILLEKVEEEARHEAAVLiKE 177

                         170       180
                  ....*....|....*....|
gi 386767625  987 EHELKMNRLKEKYEKDLVLA 1006
Cdd:PRK12704  178 IEEEAKEEADKKAKEILAQA 197

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

779-1106

5.82e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 5.82e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   779 KGLEAEINKMncdhQREVTELKRtHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFERQLEEEQrt 858
Cdd:TIGR02169  684 EGLKRELSSL----QSELRRIEN-RLDELSQELSDASRKIGEIEKEI-EQLEQEEEK--LKERLEELEEDLSSLEQEI-- 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   859 qaeqrqkltEEFAAERDRLQSELRQREnEHQARRQEALREQEQELEQAKF-EMQERMAKQEEKYQN---RVNTIEQQyqa 934
Cdd:TIGR02169  754 ---------ENVKSELKELEARIEELE-EDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRieaRLREIEQK--- 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   935 dfelwktEHENKTKLAQAEKENAIRQHYRAERDRQLDELvvrmeadalqHKEEHELKMNrlKEKYEKDLVLAESVEKSLR 1014
Cdd:TIGR02169  821 -------LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI----------EKEIENLNGK--KEELEEELEELEAALRDLE 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1015 EKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLnADIQSELGVLNERHKQEMDqlQKRVHQ 1094
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL-SEIEDPKGEDEEIPEEELS--LEDVQA 958

                          330
                   ....*....|..
gi 386767625  1095 TIQRQEETIEIL 1106
Cdd:TIGR02169  959 ELQRVEEEIRAL 970

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

677-1087

6.32e-06

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.61 E-value: 6.32e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLcekvAALTRRLESQNQAWEHRLETELARTKETTma 756
Cdd:pfam12128  478 EEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSAL----DELELQLFPQAGTLLHFLRKEAPDWEQSI-- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   757 GEKIRRERWVREN-------TKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESC 829
Cdd:pfam12128  552 GKVISPELLHRTDldpevwdGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN 631

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   830 AQDREAIIEKERTAI-----RERFeRQLEEEQRTQAEQRQKLTEE---FAAERDR-LQSELRQRENEHQA---------- 890
Cdd:pfam12128  632 GELEKASREETFARTalknaRLDL-RRLFDEKQSEKDKKNKALAErkdSANERLNsLEAQLKQLDKKHQAwleeqkeqkr 710

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   891 ----RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQaEKENAIRQHYRAER 966
Cdd:pfam12128  711 eartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKR-EIRTLERKIERIAV 789

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   967 DRQ-LDELVVRMEADALQHK--------------EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQV 1031
Cdd:pfam12128  790 RRQeVLRYFDWYQETWLQRRprlatqlsnieraiSELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767625  1032 R-----NSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQ 1087
Cdd:pfam12128  870 SklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAE 930

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

679-920

6.44e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 6.44e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  679 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 758
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  759 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 838
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  839 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 918
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 386767625  919 EK 920
Cdd:COG4942   241 ER 242

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

734-933

6.56e-06

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 50.34 E-value: 6.56e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   734 SQNQAWEHRLETElaRTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKmncdHQREVTELKRTHQMQLLDalEE 813
Cdd:pfam15709  329 EQEKASRDRLRAE--RAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELEL----EQQRRFEEIRLRKQRLEE--ER 400

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   814 ARTKHEQIETSIRESCAQDREAIIEKE--RTAIRERFERQLEEEQRTQAE-QRQKLTEEFAAERDRLQSELRQREnehqa 890
Cdd:pfam15709  401 QRQEEEERKQRLQLQAAQERARQQQEEfrRKLQELQRKKQQEEAERAEAEkQRQKELEMQLAEEQKRLMEMAEEE----- 475

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 386767625   891 rRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQ 933
Cdd:pfam15709  476 -RLEYQRQKQEAEEKARLEAEERRQKEEEAARLALEEAMKQAQ 517

PRK03918

DNA double-strand break repair ATPase Rad50;

711-1046

6.56e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 6.56e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  711 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNc 790
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK- 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  791 dhqREVTELKrthqmqllDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRErferqLEEEQRTQAEQRQKLTEEF 870
Cdd:PRK03918  419 ---KEIKELK--------KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR-----IEKELKEIEEKERKLRKEL 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  871 AAERDRLQSELRQRENEHQArrqEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLA 950
Cdd:PRK03918  483 RELEKVLKKESELIKLKELA---EQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  951 QAEKEnairqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVE---------KSLREKYAETR 1021
Cdd:PRK03918  560 ELEKK-------LDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKelereekelKKLEEELDKAF 632

                         330       340
                  ....*....|....*....|....*
gi 386767625 1022 GKLAEADAQVRNSQAEVKQLQLELS 1046
Cdd:PRK03918  633 EELAETEKRLEELRKELEELEKKYS 657

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

797-973

6.69e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 6.69e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  797 TELKRTHQMQLLDALEEARTKHEQIETSIRE----SCAQDREAIIEKERTAIRERFERQLEeeqrtQAEQRQKLTEEFAA 872
Cdd:COG4717   332 PDLSPEELLELLDRIEELQELLREAEELEEElqleELEQEIAALLAEAGVEDEEELRAALE-----QAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  873 ERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEqQYQADFELWKTEHEN---KTKL 949
Cdd:COG4717   407 LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELE-QLEEDGELAELLQELeelKAEL 485

                         170       180       190
                  ....*....|....*....|....*....|..
gi 386767625  950 AQAEKENA--------IRQHYRAERDRQLDEL 973
Cdd:COG4717   486 RELAEEWAalklalelLEEAREEYREERLPPV 517

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

769-1133

8.87e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 8.87e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  769 NTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF 848
Cdd:COG4717    69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  849 E---------RQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEE 919
Cdd:COG4717   149 EeleerleelRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE-LQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  920 KYQNRVNTIEQQYQAD-----------------------------------------------FELWKTEHENKTKLAQA 952
Cdd:COG4717   228 ELEQLENELEAAALEErlkearlllliaaallallglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEEL 307

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  953 EKENAIRQHYRAERDRQLDEL---------VVRMEADALQHKEEHELKMNRLKEKYEKDlVLAESVEKSLREKYAETRGK 1023
Cdd:COG4717   308 QALPALEELEEEELEELLAALglppdlspeELLELLDRIEELQELLREAEELEEELQLE-ELEQEIAALLAEAGVEDEEE 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1024 LAEADAQVRnsqaEVKQLQLELSHSKKMCGDIIMERDRLRDNLN-ADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEET 1102
Cdd:COG4717   387 LRAALEQAE----EYQELKEELEELEEQLEELLGELEELLEALDeEELEEELEEL-EEELEELEEELEELREELAELEAE 461

                         410       420       430
                  ....*....|....*....|....*....|...
gi 386767625 1103 IEILKGDN--DALRQQCLKLNAVIRQQRKDYCV 1133
Cdd:COG4717   462 LEQLEEDGelAELLQELEELKAELRELAEEWAA 494

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

812-1089

1.11e-05

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.84 E-value: 1.11e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   812 EEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFE------------------------RQLEEEQRTQAEQRQKL- 866
Cdd:pfam12128  214 PKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNtlesaelrlshlhfgyksdetliaSRQEERQETSAELNQLLr 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   867 --TEEFAAERDRLQSELR-QRENEHQARRQ-EALREQEQELEQAKFEMQERMAKQEEKYQN--------------RVNTI 928
Cdd:pfam12128  294 tlDDQWKEKRDELNGELSaADAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSelenleerlkaltgKHQDV 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   929 EQQYQAdfELWKTEHENKTKLAQAEKEnaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaes 1008
Cdd:pfam12128  374 TAKYNR--RRSKIKEQNNRDIAGIKDK---LAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE---------- 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1009 vEKSLREKYAETRGKLAEADA------QVRNSQAEVKQLQLELSHSKKMCGDIIMER---DRLRDNLNADIQSELGVLNE 1079
Cdd:pfam12128  439 -EYRLKSRLGELKLRLNQATAtpelllQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQASEALRQASRRLEE 517

                          330
                   ....*....|
gi 386767625  1080 RhKQEMDQLQ 1089
Cdd:pfam12128  518 R-QSALDELE 526

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

834-955

1.50e-05

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 49.05 E-value: 1.50e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  834 EAIIEKERTAI---RERFERQLE--EEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKf 908
Cdd:PRK00409  501 ENIIEEAKKLIgedKEKLNELIAslEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAI- 579

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386767625  909 emqeRMAKQE-EKYQNRVNTIEQQYQADFELWKTEhENKTKLAQAEKE 955
Cdd:PRK00409  580 ----KEAKKEaDEIIKELRQLQKGGYASVKAHELI-EARKRLNKANEK 622

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

812-953

1.63e-05

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 48.79 E-value: 1.63e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   812 EEARTKHEQIETS--IRESCAQDREAIIEkertAIRERFERQLEEEQRTQAEQR-QKLTEEFAAERDRLQSE-------- 880
Cdd:pfam15709  359 EQRRLQQEQLERAekMREELELEQQRRFE----EIRLRKQRLEEERQRQEEEERkQRLQLQAAQERARQQQEefrrklqe 434

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625   881 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEK----YQNRVNTIEQQYQADFELWKTEHENKTKLAQAE 953
Cdd:pfam15709  435 LQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEerleYQRQKQEAEEKARLEAEERRQKEEEAARLALEE 511

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

645-927

2.08e-05

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.60 E-value: 2.08e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   645 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 720
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   721 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 794
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   795 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 874
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767625   875 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 927
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

889-1129

2.11e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 2.11e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  889 QARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE----NAIRQHYRA 964
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaelEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  965 ERDRQLDELVVRMeaDALQhkeehelKMNRlkEKYEKDLVLAESVEKSLR-----EKYAETRGKLAEadaQVRNSQAEVK 1039
Cdd:COG4942    98 ELEAQKEELAELL--RALY-------RLGR--QPPLALLLSPEDFLDAVRrlqylKYLAPARREQAE---ELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1040 QLQLELSHskkmcgdiimERDRLRdNLNADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLK 1119
Cdd:COG4942   164 ALRAELEA----------ERAELE-ALLAELEEERAAL-EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|
gi 386767625 1120 LNAVIRQQRK 1129
Cdd:COG4942   232 LEAEAAAAAE 241

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

819-993

2.32e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 48.33 E-value: 2.32e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  819 EQIETSIRESCAQDREAII---EKERTAIRERFERQLEEEQRTQAEQRqklteefaAERDRLQSELRQRENEHQARRQEA 895
Cdd:COG2268   196 EIIRDARIAEAEAERETEIaiaQANREAEEAELEQEREIETARIAEAE--------AELAKKKAEERREAETARAEAEAA 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  896 LREQEQELEQAKfEMQERMAKQEEkyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHyRAERDRQLDELVV 975
Cdd:COG2268   268 YEIAEANAEREV-QRQLEIAERER--EIELQEKEAEREE-----AELEADVRKPAEAEKQAAEAEA-EAEAEAIRAKGLA 338

                         170
                  ....*....|....*...
gi 386767625  976 rmEADALQHKEEHELKMN 993
Cdd:COG2268   339 --EAEGKRALAEAWNKLG 354

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

645-1100

3.87e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 3.87e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  645 QLARRVIALSLRANELANAIHMSK----EHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKG- 719
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGd 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  720 ---SLCEKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKI---RRERWVR-----ENTKKIKELTVKGLEAEINKM 788
Cdd:COG4913   339 rleQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAEEfaaLRAEAAAllealEEELEALEEALAEAEAALRDL 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  789 NCDH---QREVTELKRT------HQMQLLDALEEA-----------------RTKHEQIETSI-------------RESC 829
Cdd:COG4913   418 RRELrelEAEIASLERRksnipaRLLALRDALAEAlgldeaelpfvgelievRPEEERWRGAIervlggfaltllvPPEH 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  830 AQDREAIIEKERTAIRERFER---QLEEEQRTQAEQRQ---KLTEEFAAERDRLQSELRQREN----------------- 886
Cdd:COG4913   498 YAAALRWVNRLHLRGRLVYERvrtGLPDPERPRLDPDSlagKLDFKPHPFRAWLEAELGRRFDyvcvdspeelrrhprai 577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  887 -------------EHQARRQ---------------EALREQEQELEQAKFEMQERMAKQEEKYQNRvntieQQYQADFEL 938
Cdd:COG4913   578 tragqvkgngtrhEKDDRRRirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDAL-----QERREALQR 652

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  939 WKTEHENKTKLAQAEKEnairqhyRAERDRQLDELvvRMEADALQhkeehelkmnRLKEKYEKdlvlAESVEKSLREKYA 1018
Cdd:COG4913   653 LAEYSWDEIDVASAERE-------IAELEAELERL--DASSDDLA----------ALEEQLEE----LEAELEELEEELD 709

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1019 ETRGKLAEADAQVRNSQAEVKQLQLELShskkmcGDIIMERDRLRDNLNADIQSELGvlNERHKQEMDQLQKRVHQTIQR 1098
Cdd:COG4913   710 ELKGEIGRLEKELEQAEEELDELQDRLE------AAEDLARLELRALLEERFAAALG--DAVERELRENLEERIDALRAR 781


                  ..
gi 386767625 1099 QE 1100
Cdd:COG4913   782 LN 783

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

845-1046

4.01e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 4.01e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  845 RERFERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQREnehqaRRQEALREQEQELEQAKFEMQERMA---KQEEKY 921
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKEL-AALKKEEKALLKQLAALE-----RRIAALARRIRALEQELAALEAELAeleKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  922 QNRVNTIEQQYQADF-ELWKTEHENKTKL-------AQAEKENAIRQHYRAERDRQLDELVVRME--ADALQHKEEHELK 991
Cdd:COG4942    96 RAELEAQKEELAELLrALYRLGRQPPLALllspedfLDAVRRLQYLKYLAPARREQAEELRADLAelAALRAELEAERAE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 386767625  992 MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELS 1046
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

749-1122

4.44e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 4.44e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   749 RTKETTMAGEKIRRERWVRENTKKIKeltvKGLEAEINKMncDHQREVTELKRTHQMQLLDALEEARTKHEQietSIRES 828
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKK----KSLHGKAELL--TLRSQLLTLCTPCMPDTYHERKQVLEKELK---HLREA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   829 CAQDRE--AIIEKERTAIRERFERQLE-EEQRTQAEQRQKLTEEFAAERDRLQ---------------SELRQRENEHQA 890
Cdd:TIGR00618  235 LQQTQQshAYLTQKREAQEEQLKKQQLlKQLRARIEELRAQEAVLEETQERINrarkaaplaahikavTQIEQQAQRIHT 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   891 RRQEALREQEQELEQAKFEMQERMAKQEEKyqnrvnTIEQQYQADFELWKTEHENKTK-LAQAEKENAIRQHYRAERdrq 969
Cdd:TIGR00618  315 ELQSKMRSRAKLLMKRAAHVKQQSSIEEQR------RLLQTLHSQEIHIRDAHEVATSiREISCQQHTLTQHIHTLQ--- 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   970 ldelvvrmeadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAEtRGKLAEADAQVRNSQAEVKQLQLELSHSK 1049
Cdd:TIGR00618  386 -------------QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDL-QGQLAHAKKQQELQQRYAELCAAAITCTA 451

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 386767625  1050 KMCGDIIMERDRLRDNLNADIQSElgvlnerhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNA 1122
Cdd:TIGR00618  452 QCEKLEKIHLQESAQSLKEREQQL---------QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNP 515

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

843-1041

4.75e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.11 E-value: 4.75e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERFERQLEEE--QRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEM----QERMAK 916
Cdd:PRK09510   59 AVVEQYNRQQQQQksAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAAlkqkQAEEAA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  917 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLK 996
Cdd:PRK09510  139 AKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKA-----AAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAA 213

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 386767625  997 EKYEKDLVLAESV-EKSLREKYAETRGKLAEADAQVRNSQAEVKQL 1041
Cdd:PRK09510  214 EAKKKAAAEAKAAaAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEV 259

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

785-1003

5.11e-05

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 45.81 E-value: 5.11e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   785 INKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiekertairerfeRQLEEEQRTQAEQRQ 864
Cdd:pfam15665    5 LNTKNDEHEAEIQALKEAHEEEIQQILAETREKILQYKSKIGEELDLKRRI--------------QTLEESLEQHERMKR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   865 KLTEEFAAERDRLQSELRQRENEHQARrqeaLREQEQELEQAKFEMQER-------MAKQEEKYQNRVNTIEQQYQADFE 937
Cdd:pfam15665   71 QALTEFEQYKRRVEERELKAEAEHRQR----VVELSREVEEAKRAFEEKlesfeqlQAQFEQEKRKALEELRAKHRQEIQ 146

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625   938 LWKTEHENKTKLAQAEKENaIRQHYRAERDrQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDL 1003
Cdd:pfam15665  147 ELLTTQRAQSASSLAEQEK-LEELHKAELE-SLRKEVEDLRKEKKKLAEEYEQKLSKAQAFYEREL 210

mukB

chromosome partition protein MukB;

792-1116

5.21e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 5.21e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  792 HQREVTELKRthqmQLLDALEEARTKHEQIETSIRESCAQ-DREAIIEKERTAIRERFerQLEEEQRTQAEQRQKLTEEF 870
Cdd:PRK04863  284 HLEEALELRR----ELYTSRRQLAAEQYRLVEMARELAELnEAESDLEQDYQAASDHL--NLVQTALRQQEKIERYQADL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  871 AAERDRL--QSELRQRENEHQARRQEALREQEQELEQAK---------FEMQERMAKQeekYQNRVNTIEQQYQ----AD 935
Cdd:PRK04863  358 EELEERLeeQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQ---YQQAVQALERAKQlcglPD 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  936 FEL-----WKTEHENKTKLA-----QAEK-----ENAIRQHYRAErdrqldELVVRMeADALQHKEEHElKMNRLKEKYE 1000
Cdd:PRK04863  435 LTAdnaedWLEEFQAKEQEAteellSLEQklsvaQAAHSQFEQAY------QLVRKI-AGEVSRSEAWD-VARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1001 KDLVLAESVEkSLREKYAETRGKLaeadaqvrNSQAEVKQLQLELSHskkmcgdiimerdrlRDNLNADIQSELGVLNER 1080
Cdd:PRK04863  507 EQRHLAEQLQ-QLRMRLSELEQRL--------RQQQRAERLLAEFCK---------------RLGKNLDDEDELEQLQEE 562

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 386767625 1081 HKQEMDQLQKRVHQTIQRQEET---IEILKGDNDALRQQ 1116
Cdd:PRK04863  563 LEARLESLSESVSEARERRMALrqqLEQLQARIQRLAAR 601

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

809-957

5.85e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.72 E-value: 5.85e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  809 DALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAErdrlQSELRQRENEH 888
Cdd:PRK09510   76 RAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK----AAAAAKAKAEA 151

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767625  889 QARRQEALREQEQElEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 957
Cdd:PRK09510  152 EAKRAAAAAKKAAA-EAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKA 219

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

978-1129

7.16e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.16e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  978 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1055
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1056 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1125
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 386767625 1126 QQRK 1129
Cdd:COG3206   338 QLEA 341

Caldesmon

pfam02029

Caldesmon;

819-1107

7.59e-05

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 46.78 E-value: 7.59e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   819 EQIETSIRESCAQDREAIIEKERTAIRERfERQLEEEQRTQAEQRQKLTEEFAA--ERDRLQSELRQRENEHQARRQEAL 896
Cdd:pfam02029    5 EEAARERRRRAREERRRQKEEEEPSGQVT-ESVEPNEHNSYEEDSELKPSGQGGldEEEAFLDRTAKREERRQKRLQEAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   897 REQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDrqldelvvR 976
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEE--------E 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   977 MEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAeadAQVRNSQAEVKQLQLELSHSKKMCGDII 1056
Cdd:pfam02029  156 GEEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGH---PEVKSQNGEEEVTKLKVTTKRRQGGLSQ 232

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 386767625  1057 MERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILK 1107
Cdd:pfam02029  233 SQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELK 283

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

801-918

7.66e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.00 E-value: 7.66e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  801 RTHQMQLLDALEEARTKHEQIETsirescaqDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLTEEFAAERDRLQSE 880
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEI--------EKEALKKEQDEASFERLAE-LRDELAELEEELEALKARWEAEKELIEEI 473

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767625  881 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQE 918
Cdd:COG0542   474 QELKEELEQRYGKIPELEKELAELEEELAELAPLLREE 511

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

740-998

7.69e-05

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 46.07 E-value: 7.69e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   740 EHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHE 819
Cdd:pfam13868   87 QKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   820 QIETSIREscaqdrEAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQ 899
Cdd:pfam13868  167 REEEREAE------REEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   900 EQELEQAKFEMQERMAKQEEKYQNRVntieqqyqadfeLWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEA 979
Cdd:pfam13868  241 REEQIELKERRLAEEAEREEEEFERM------------LRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAA 308

                          250
                   ....*....|....*....
gi 386767625   980 DALQHKEEHELKMNRLKEK 998
Cdd:pfam13868  309 EREEELEEGERLREEEAER 327

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

807-1038

8.44e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 8.44e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  807 LLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQKLTEEFAAERDRLqSELRQREN 886
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEA------EEKEEEYAELQEELEELEEELEELEAEL-EELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  887 EHqaRRQEALREQEQELEQAKFEMQErmakqeekYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKEnaiRQHYRAER 966
Cdd:COG4717   120 KL--EKLLQLLPLYQELEALEAELAE--------LPERLEELEERLEE-------LRELEEELEELEAE---LAELQEEL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767625  967 DRQLDELVVRMEADALQHKEEHELKMNRLKEkYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEV 1038
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAE-LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARL 250

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

652-990

8.59e-05

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.89 E-value: 8.59e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   652 ALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV----VTRHQGFIEQllkdkgSLCEKVAA 727
Cdd:TIGR00618  574 ILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdVRLHLQQCSQ------ELALKLTA 647

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   728 LTRRLEsqNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQL 807
Cdd:TIGR00618  648 LHALQL--TLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   808 LD--ALEEARTKHEQIETSIRESCAQDREAIieKERTAIRER-FERQLEEEQR-TQAEQRQKLTEEFAAERDRLQSELRQ 883
Cdd:TIGR00618  726 ASssLGSDLAAREDALNQSLKELMHQARTVL--KARTEAHFNnNEEVTAALQTgAELSHLAAEIQFFNRLREEDTHLLKT 803

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   884 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQnRVNTIEQQYQADfelwkteHENKTKLAQAEKENAiRQHYR 963
Cdd:TIGR00618  804 LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA-TLGEITHQLLKY-------EECSKQLAQLTQEQA-KIIQL 874

                          330       340
                   ....*....|....*....|....*..
gi 386767625   964 AERDRQLDELVVRMEADALQhKEEHEL 990
Cdd:TIGR00618  875 SDKLNGINQIKIQFDGDALI-KFLHEI 900

PRK07353

F0F1 ATP synthase subunit B'; Validated

839-906

8.97e-05

F0F1 ATP synthase subunit B'; Validated

Pssm-ID: 235999 [Multi-domain] Cd Length: 140 Bit Score: 43.84 E-value: 8.97e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767625  839 KERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSE-LRQRENEHQARRQEALREQEQELEQA 906
Cdd:PRK07353   49 KERLAEAEKLEAQYEQQLASARKQAQAVIAEAEAEADKLAAEaLAEAQAEAQASKEKARREIEQQKQAA 117

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

767-981

1.29e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 1.29e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  767 RENTKKIKEL--TVKGLEAEINKMNCDHQREVTELKRTHQM--QLLDALEEARTKHEQIETSIREscAQDREAIIEKERT 842
Cdd:COG4942    23 AEAEAELEQLqqEIAELEKELAALKKEEKALLKQLAALERRiaALARRIRALEQELAALEAELAE--LEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERFERQLEEEQRTQAEQRQKL---TEEFAAERDRLQ-----SELRQRENEHQARRQEALREQEQELEQAKFEMQERM 914
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQylkylAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  915 AKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnairqhyraerDRQLDELVVRMEADA 981
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE-----------AEELEALIARLEAEA 236

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

805-917

1.63e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 44.88 E-value: 1.63e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  805 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 879
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767625  880 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 917
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

831-1018

1.95e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.71 E-value: 1.95e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  831 QDREAiiekertAIRERfERQLEEEQRTQAEQR--QKLTEE----FAA-------ERDRLQSELRQRENEHQARRQEALR 897
Cdd:COG3096   232 QDMEA-------ALREN-RMTLEAIRVTQSDRDlfKHLITEatnyVAAdymrhanERRELSERALELRRELFGARRQLAE 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  898 EQEQeleqakfemQERMAKQEEKYQNRVNTIEQQYQAdfelwKTEHENK--TKLAQAEKenaiRQHYRAErdrqLDELVV 975
Cdd:COG3096   304 EQYR---------LVEMARELEELSARESDLEQDYQA-----ASDHLNLvqTALRQQEK----IERYQED----LEELTE 361

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767625  976 RMEADALQHKEEHElkmnrLKEKYEKDLVLAESVEKSLREKYA 1018
Cdd:COG3096   362 RLEEQEEVVEEAAE-----QLAEAEARLEAAEEEVDSLKSQLA 399

PRK02224

DNA double-strand break repair Rad50 ATPase;

795-1047

2.17e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.42 E-value: 2.17e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  795 EVTELKRTHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAA 872
Cdd:PRK02224  468 ETIEEDRERVEELEAELEDLEEEVEEVEERL-ERAEDLVEA--EDRIERLEERREDleELIAERRETIEEKRERAEELRE 544

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  873 ERDRLQSELRQRENEHQARRQEAlreqEQELEQAKfEMQERMAKQEEKYQnRVNTIEQQYQADFELWKTEHENKTKLAQ- 951
Cdd:PRK02224  545 RAAELEAEAEEKREAAAEAEEEA----EEAREEVA-ELNSKLAELKERIE-SLERIRTLLAAIADAEDEIERLREKREAl 618

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  952 AEKENAIRQHYRAERDRQlDELVVRMEADALQHKEEHelkmnrlKEKYEKDLvlaESVEKSLREKyAETRGKLAEADAQV 1031
Cdd:PRK02224  619 AELNDERRERLAEKRERK-RELEAEFDEARIEEARED-------KERAEEYL---EQVEEKLDEL-REERDDLQAEIGAV 686

                         250
                  ....*....|....*.
gi 386767625 1032 RNSQAEVKQLQLELSH 1047
Cdd:PRK02224  687 ENELEELEELRERREA 702

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

645-936

2.32e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 2.32e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   645 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 715
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   716 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 793
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   794 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 871
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625   872 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 936
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

830-1046

2.73e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.45 E-value: 2.73e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   830 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF-AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKF 908
Cdd:TIGR02794   64 KKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAkQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERK 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   909 EMQERMAKQEEKYQNRVNTIEQQyQADFELWKTEHENKTKlaqaekenairqhyrAERDRQLDELVVRMEADALQHKEEH 988
Cdd:TIGR02794  144 AKEEAAKQAEEEAKAKAAAEAKK-KAEEAKKKAEAEAKAK---------------AEAEAKAKAEEAKAKAEAAKAKAAA 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625   989 ELKMNRLKEKYEKDLVLAESVEKSLRekyAETRGKLAEADAQVRNSQAEVKQLQLELS 1046
Cdd:TIGR02794  208 EAAAKAEAEAAAAAAAEAERKADEAE---LGDIFGLASGSNAEKQGGARGAAAGSEVD 262

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

711-912

2.78e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 2.78e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  711 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTmagekiRRERWVRENTKKIKELTVKGLEAEINKMnc 790
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA------RLEAALRRAVTLAGRLREVTLEGEGGSA-- 658

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  791 dhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF 870
Cdd:COG1196   659 --GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767625  871 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQE 912
Cdd:COG1196   737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

843-1044

2.92e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 2.92e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERFERQLEEEQRTQAEQRQKLTEEfaaERDRLQSELRQRENEHQARRQE----ALREQEQELEQAKFEMQERMAK-- 916
Cdd:COG3206   156 ALAEAYLEQNLELRREEARKALEFLEE---QLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQQLSELESQLAEar 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  917 -QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDE--LVVRMEA--DALQHKEEHELK 991
Cdd:COG3206   233 aELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNhpDVIALRAqiAALRAQLQQEAQ 312

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 386767625  992 mnRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEAdaqvrnSQAEVKQLQLE 1044
Cdd:COG3206   313 --RILASLEAELEALQAREASLQAQLAQLEARLAEL------PELEAELRRLE 357

growth_prot_Scy

NF041483

polarized growth protein Scy;

729-1041

3.45e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 44.82 E-value: 3.45e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  729 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 795
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  796 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 875
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  876 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 955
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  956 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1023
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 386767625 1024 ------LAEADAQVRNSQAEVKQL 1041
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

812-992

3.79e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.56 E-value: 3.79e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   812 EEARTKHEQIETSIRESCAQDREAIIEKERTairERFERQLEEEQRTQAE------QRQKLTEEFAAERDRLQSELRQRE 885
Cdd:pfam15709  341 ERAEMRRLEVERKRREQEEQRRLQQEQLERA---EKMREELELEQQRRFEeirlrkQRLEEERQRQEEEERKQRLQLQAA 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   886 NEHQARRQEALREQEQELEQAKfemQERMAKQEEKYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKENAIRQHYRAE 965
Cdd:pfam15709  418 QERARQQQEEFRRKLQELQRKK---QQEEAERAEAEKQRQKELEMQLAE-------EQKRLMEMAEEERLEYQRQKQEAE 487

                          170       180
                   ....*....|....*....|....*..
gi 386767625   966 RDRQLdelvvrmEADALQHKEEHELKM 992
Cdd:pfam15709  488 EKARL-------EAEERRQKEEEAARL 507

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

826-930

4.33e-04

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 41.95 E-value: 4.33e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   826 RESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ---- 901
Cdd:pfam05672   27 REREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQkeea 106

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 386767625   902 ------ELEQAKFEMQERMAKQEEKYQNRVNTIEQ 930
Cdd:pfam05672  107 eakareEAERQRQEREKIMQQEEQERLERKKRIEE 141

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

804-934

4.55e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 4.55e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  804 QMQLLDA---LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRT--------QA--EQRQKLT 867
Cdd:COG3206   225 ESQLAEAraeLAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLaelEAELAELSARytpnhpdvIAlrAQIAALR 304

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  868 EEFAAERDRLQSELRQrENEHQARRQEALREQEQELEQAKFEMQERMAKQEEkYQNRVNTIEQQYQA 934
Cdd:COG3206   305 AQLQQEAQRILASLEA-ELEALQAREASLQAQLAQLEARLAELPELEAELRR-LEREVEVARELYES 369

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

645-1045

5.17e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.16 E-value: 5.17e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  645 QLARRVIALSLRANELANAIHMSKEHvfqlRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 724
Cdd:COG1196   334 ELEEELEELEEELEEAEEELEEAEAE----LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  725 VAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQ 804
Cdd:COG1196   410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  805 MQLLDALEEARTKHEQIETSIRESCAQDREAII-----------EKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAE 873
Cdd:COG1196   490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  874 RD--------------RLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM----AKQEEKYQNRVNTIEQQYQAD 935
Cdd:COG1196   570 KAgratflpldkirarAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvAARLEAALRRAVTLAGRLREV 649

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  936 FELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE 1015
Cdd:COG1196   650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 386767625 1016 KYAETRGKLAE-----------------ADAQVRNSQAEVKQLQLEL 1045
Cdd:COG1196   730 LEAEREELLEElleeeelleeealeelpEPPDLEELERELERLEREI 776

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

811-934

5.65e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 43.33 E-value: 5.65e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  811 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRtqaEQRQKLTEEfaaERdRLQSELRQRENEHQA 890
Cdd:cd16269   176 LQSKEAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQR---ELEQKLEDQ---ER-SYEEHLRQLKEKMEE 248

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 386767625  891 RRQEALREQEQELEQakfEMQERMAKQEEKYQNRVNTIEQQYQA 934
Cdd:cd16269   249 ERENLLKEQERALES---KLKEQEALLEEGFKEQAELLQEEIRS 289

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

742-1104

6.29e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.19 E-value: 6.29e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   742 RLETELARTKETTMagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDhQREVTELKRTHQMQLLDALEEARTKHEQI 821
Cdd:pfam02463  170 KKKEALKKLIEETE--NLAELIIDLEELKLQELKLKEQAKKALEYYQLKE-KLELEEEYLLYLDYLKLNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   822 ETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERdrLQSELRQRENEHQARRQEALREQEQ 901
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK--SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   902 ELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADA 981
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   982 LQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyaetrgklaeaDAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDR 1061
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESI-----------ELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 386767625  1062 LrdnlnadiQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1104
Cdd:pfam02463  474 L--------KETQLVKLQEQLELLLSRQKLEERSQKESKARSG 508

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

645-1044

6.60e-04

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 6.60e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   645 QLARRVIALSLRANELANAIHMSKEHVFQLRgEKQKslraEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 724
Cdd:pfam07888   70 QWERQRRELESRVAELKEELRQSREKHEELE-EKYK----ELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQR 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   725 VaaLTRrlesqnqawehrlETELARTKETTmagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQrevtELKRTHQ 804
Cdd:pfam07888  145 V--LER-------------ETELERMKERA---KKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ----ELRNSLA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   805 MQLLDALeeaRTKHEQIETSIRESCAQDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLtEEFAAERDRLQSELrqr 884
Cdd:pfam07888  203 QRDTQVL---QLQDTITTLTQKLTTAHRKEAENEALLEELRSLQER-LNASERKVEGLGEEL-SSMAAQRDRTQAEL--- 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   885 eneHQARRQEAlrEQEQELEQAKFEMQERMAKqeekyqnrvntieqqyqadfelWKTEHENKTKLAQAEKEnairqhyra 964
Cdd:pfam07888  275 ---HQARLQAA--QLTLQLADASLALREGRAR----------------------WAQERETLQQSAEADKD--------- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   965 eRDRQLDELVVRMEAdALQhkeehELKMNRLKEKYEkdlvLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1044
Cdd:pfam07888  319 -RIEKLSAELQRLEE-RLQ-----EERMEREKLEVE----LGREKDCN-RVQLSESRRELQELKASLRVAQKEKEQLQAE 386

Caldesmon

pfam02029

Caldesmon;

677-922

6.66e-04

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 43.70 E-value: 6.66e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSlCEKVAALTRRLESQNQAW---EHRLETELARTKET 753
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGR-YKEEETEIREKEYQENKWsteVRQAEEEGEEEEDK 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   754 TMAGEKIRRERWVRENTKKI---KELTVKgleaEINKMNCDHQREVTELKrTHQMQLLDALEEARTKHEQIETSIRESCA 830
Cdd:pfam02029  163 SEEAEEVPTENFAKEEVKDEkikKEKKVK----YESKVFLDQKRGHPEVK-SQNGEEEVTKLKVTTKRRQGGLSQSQERE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   831 QDREAIIEKERTAIRERFERQ-LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ-RENEHQARRQEALREQ---EQELEQ 905
Cdd:pfam02029  238 EEAEVFLEAEQKLEELRRRRQeKESEEFEKLRQKQQEAELELEELKKKREERRKlLEEEEQRRKQEEAERKlreEEEKRR 317

                          250
                   ....*....|....*..
gi 386767625   906 AKFEMQERMAKQEEKYQ 922
Cdd:pfam02029  318 MKEEIERRRAEAAEKRQ 334

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

845-973

7.52e-04

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 43.04 E-value: 7.52e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   845 RERFERQLEEEQR--TQAEQ--RQKLTEEFAAERDRLQSE----LRQRENEHQARRQEALREQEQELEQAKFEMQERMAK 916
Cdd:pfam02841  157 RDKLEAKYNQVPRkgVKAEEvlQEFLQSKEAVEEAILQTDqaltAKEKAIEAERAKAEAAEAEQELLREKQKEEEQMMEA 236

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625   917 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDEL 973
Cdd:pfam02841  237 QERSYQEHVKQLIEKMEAEREQLLAEQERMLEHKLQEQEELLKEGFKTEAESLQKEI 293

PRK12704

phosphodiesterase; Provisional

771-935

8.27e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.23 E-value: 8.27e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  771 KKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQiETSIRESCAQDREA-IIEKErtairERFE 849
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEK-ELRERRNELQKLEKrLLQKE-----ENLD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  850 RQLEEeqrtqAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ----ELEQAKFEMQERMaKQEEKYQ--N 923
Cdd:PRK12704  100 RKLEL-----LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisglTAEEAKEILLEKV-EEEARHEaaV 173

                         170
                  ....*....|..
gi 386767625  924 RVNTIEQQYQAD 935
Cdd:PRK12704  174 LIKEIEEEAKEE 185

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

851-1101

9.14e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.57 E-value: 9.14e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   851 QLEEEQRTQAEQR----QKLTEEFAAERDRLqSELRQRENEHQARRQEALREQEQELEQAKF---EMQERMAKQEEKYQN 923
Cdd:pfam15921   99 ELHEKQKFYLRQSvidlQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELEAAKClkeDMLEDSNTQIEQLRK 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   924 RVNTIEQQYQ------ADFELWKT----EHENKTKLAQAEKENAIRQHYRaERDRQLDELVVR----------------- 976
Cdd:pfam15921  178 MMLSHEGVLQeirsilVDFEEASGkkiyEHDSMSTMHFRSLGSAISKILR-ELDTEISYLKGRifpvedqlealksesqn 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   977 -MEADALQHKE-------EHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHS 1048
Cdd:pfam15921  257 kIELLLQQHQDrieqlisEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA 336

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  1049 KKMCGDIIMERDRLRDNLNADIqSELGVLNERHKQEM----DQLQKRVHQTIQRQEE 1101
Cdd:pfam15921  337 KRMYEDKIEELEKQLVLANSEL-TEARTERDQFSQESgnldDQLQKLLADLHKREKE 392

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

923-1103

9.47e-04

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.47e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  923 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 1000
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1001 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1066
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767625 1067 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1103
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

854-1044

9.64e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 43.02 E-value: 9.64e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   854 EEQRTQAEQRQKLT---EEFAAERDRL---QSELRQRENEHQARRQEALREQEQEleqaKFEMQERMAKQEEKYQNRV-- 925
Cdd:pfam15709  312 EEERSEEDPSKALLekrEQEKASRDRLraeRAEMRRLEVERKRREQEEQRRLQQE----QLERAEKMREELELEQQRRfe 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   926 -NTIEQQYQADFELWKTEHENKTKLA-QAEKENAIRQhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKY-EKD 1002
Cdd:pfam15709  388 eIRLRKQRLEEERQRQEEEERKQRLQlQAAQERARQQ--QEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLaEEQ 465

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 386767625  1003 LVLAESVEKS----LREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1044
Cdd:pfam15709  466 KRLMEMAEEErleyQRQKQEAEEKARLEAEERRQKEEEAARLALEE 511

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

778-1104

1.05e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 1.05e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   778 VKGLEAEINKMNCDHQREVTELKRThQMQLLDALEEARTKHEQIeTSIRESCAQDREAIIEKERTAIRER-----FERQL 852
Cdd:pfam15921   87 VKDLQRRLNESNELHEKQKFYLRQS-VIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELeaakcLKEDM 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   853 EEEQRTQAEQRQKLTEEFAAERDRLQSELRQREN-------EHQARR-----------QEALREQEQELEQAK---FEMQ 911
Cdd:pfam15921  165 LEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMStmhfrslgsaiSKILRELDTEISYLKgriFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   912 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENK----TKLAQAEKENA---------IRQHYRAERD---RQLDEL-- 973
Cdd:pfam15921  245 DQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEitglTEKASSARSQAnsiqsqleiIQEQARNQNSmymRQLSDLes 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   974 -VVRMEADALQHKEEHELKMnrlkEKYEKDLVLAES---VEKSLREKYAETRGKLaeaDAQVRNSQAEV----KQLQLEL 1045
Cdd:pfam15921  325 tVSQLRSELREAKRMYEDKI----EELEKQLVLANSeltEARTERDQFSQESGNL---DDQLQKLLADLhkreKELSLEK 397

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625  1046 SHSKKM----CGDIIMeRDRLR---DNLNADIQsELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1104
Cdd:pfam15921  398 EQNKRLwdrdTGNSIT-IDHLRrelDDRNMEVQ-RLEALLKAMKSECQGQMERQMAAIQGKNESLE 461

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

860-1044

1.09e-03

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.53 E-value: 1.09e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   860 AEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEAlrEQEQELEQAKFEMQErmAKQEEkyQNRVNTIEQQYQADFELW 939
Cdd:TIGR02794   53 NRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQ--ARQKELEQRAAAEKA--AKQAE--QAAKQAEEKQKQAEEAKA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   940 KTEHENKtklAQAEKENAIRQHYRAERDRqldELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyAE 1019
Cdd:TIGR02794  127 KQAAEAK---AKAEAEAERKAKEEAAKQA---EEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAK-AE 199

                          170       180
                   ....*....|....*....|....*
gi 386767625  1020 TRGKLAEADAQVRNSQAEVKQLQLE 1044
Cdd:TIGR02794  200 AAKAKAAAEAAAKAEAEAAAAAAAE 224

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

652-1107

1.14e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.18 E-value: 1.14e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   652 ALSLRANELANAIHMSKEHVFQLrgekQKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGSlceKVAALTRR 731
Cdd:pfam15921  221 AISKILRELDTEISYLKGRIFPV----EDQLEALKSESQNKI-------ELLLQQHQDRIEQLISEHEV---EITGLTEK 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   732 LESqnqawehrletelARTKETTMAGE-KIRRERWVRENTKKIKEL-----TVKGLEAEINKMNCDHQREVTELKRthQM 805
Cdd:pfam15921  287 ASS-------------ARSQANSIQSQlEIIQEQARNQNSMYMRQLsdlesTVSQLRSELREAKRMYEDKIEELEK--QL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   806 QLLDA-LEEARTKHEQIEtsiRESCAQDREaiIEKERTAIRERferqlEEEQRTQAEQRQKLTEEFAAER---DRLQSEL 881
Cdd:pfam15921  352 VLANSeLTEARTERDQFS---QESGNLDDQ--LQKLLADLHKR-----EKELSLEKEQNKRLWDRDTGNSitiDHLRREL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   882 RQRENEHQarRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKT-------------- 947
Cdd:pfam15921  422 DDRNMEVQ--RLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmtlessertvs 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   948 --KLAQAEKENAIR------QHYRAERDRQLDELV-VRMEADALQHKEEH----ELKMNR-------LKEKYEKDLVL-- 1005
Cdd:pfam15921  500 dlTASLQEKERAIEatnaeiTKLRSRVDLKLQELQhLKNEGDHLRNVQTEcealKLQMAEkdkvieiLRQQIENMTQLvg 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1006 -------AESVEKSLREK-YAETRGKLAE-------ADAQVRNSQAEVKQLQLEL-------SHSKKMCGDIIMERDRLR 1063
Cdd:pfam15921  580 qhgrtagAMQVEKAQLEKeINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKvklvnagSERLRAVKDIKQERDQLL 659

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 386767625  1064 DNLNADiQSELGVLNErhkqEMDQLQKRVHQTIQRQEETIEILK 1107
Cdd:pfam15921  660 NEVKTS-RNELNSLSE----DYEVLKRNFRNKSEEMETTTNKLK 698

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

810-976

1.20e-03

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.53 E-value: 1.20e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   810 ALEEARTKHEQIETSIREScAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 889
Cdd:TIGR02794   79 EAEKQRAAEQARQKELEQR-AAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAK 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   890 ARRQEAlREQEQELEQAKFEmQERMAKQEEKYQNRVNtiEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQ 969
Cdd:TIGR02794  158 AKAAAE-AKKKAEEAKKKAE-AEAKAKAEAEAKAKAE--EAKAKAEAAKAKAAAEAAAKAEAEAAAAA-----AAEAERK 228


                   ....*..
gi 386767625   970 LDELVVR 976
Cdd:TIGR02794  229 ADEAELG 235

PRK12705

hypothetical protein; Provisional

799-937

1.59e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.39 E-value: 1.59e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  799 LKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREaiiEKERTAIRERFERQLEEEQRTQAEQRQ--------KLTEEF 870
Cdd:PRK12705   31 LAKEAERILQEAQKEAEEKLEAALLEAKELLLRERN---QQRQEARREREELQREEERLVQKEEQLdaraekldNLENQL 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625  871 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM-AKQEEKYQNRVNTIEQQYQADFE 937
Cdd:PRK12705  108 EEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLdAELEEEKAQRVKKIEEEADLEAE 175

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

811-1032

1.69e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.69e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  811 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFErQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQA 890
Cdd:COG3206   184 LPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS-ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  891 RRQEALREQEQELEQAKFEMQERMAKQEEKYQ---NRVNTIEQQYQAdfelwktehENKTKLAQAEKENAIRQHYRAERD 967
Cdd:COG3206   263 PVIQQLRAQLAELEAELAELSARYTPNHPDVIalrAQIAALRAQLQQ---------EAQRILASLEAELEALQAREASLQ 333

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767625  968 RQLDELVVRMEADAlqhkeEHELKMNRLKEKYEkdlvLAESVEKSLREKYAETRGKLAEADAQVR 1032
Cdd:COG3206   334 AQLAQLEARLAELP-----ELEAELRRLEREVE----VARELYESLLQRLEEARLAEALTVGNVR 389

mukB

chromosome partition protein MukB;

843-975

2.58e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 2.58e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  843 AIRERFERQleEEQRTQAEQRQKLTEEFAAERDRLQSELRqreNEHQARRQEaLREQEQELE----QAKFEMQERMAKQE 918
Cdd:PRK04863  989 KLRQRLEQA--EQERTRAREQLRQAQAQLAQYNQVLASLK---SSYDAKRQM-LQELKQELQdlgvPADSGAEERARARR 1062

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767625  919 EKYQNRVNTIEQQyqadfelwKTEHENKTKLAQAEKENAIRQHYRAERD-RQLDELVV 975
Cdd:PRK04863 1063 DELHARLSANRSR--------RNQLEKQLTFCEAEMDNLTKKLRKLERDyHEMREQVV 1112

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

791-1072

2.94e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.86 E-value: 2.94e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  791 DHQREVTElKRTHQMQLLDALEEARTKHEQ--------IETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQ 862
Cdd:COG3096   272 DYMRHANE-RRELSERALELRRELFGARRQlaeeqyrlVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIE 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  863 RQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAK---------FEMQERMAKQeekYQNRVNTIEQQYQ 933
Cdd:COG3096   351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladyqqaLDVQQTRAIQ---YQQAVQALEKARA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  934 ---------ADFELWKTEH------------ENKTKLAQAEKenAIRQHYRA-ERDRQLDELVVRMEA-----DALQHKE 986
Cdd:COG3096   428 lcglpdltpENAEDYLAAFrakeqqateevlELEQKLSVADA--ARRQFEKAyELVCKIAGEVERSQAwqtarELLRRYR 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  987 EHELKMNR---LKEKY---EKDLVLAESVEKSLREKYAETRGKLAEADaQVRNSQAEVKQLQLELSHSKKMCGDIIMERD 1060
Cdd:COG3096   506 SQQALAQRlqqLRAQLaelEQRLRQQQNAERLLEEFCQRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVEQRSELR 584

                         330
                  ....*....|..
gi 386767625 1061 RLRDNLNADIQS 1072
Cdd:COG3096   585 QQLEQLRARIKE 596

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

767-957

3.46e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.97 E-value: 3.46e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  767 RENTKKIKELT--VKGLEAEINKMncdhQREVTELKRTHQmQLLDALEEARTKHEQIETSIrescaQDREAIIEKERTAI 844
Cdd:COG3883    19 QAKQKELSELQaeLEAAQAELDAL----QAELEELNEEYN-ELQAELEALQAEIDKLQAEI-----AEAEAEIEERREEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  845 RERFERQLEEEQ------------------------RTQAEQRQKLTEEFAAERDRLQSELRQRENEhqarrQEALREQE 900
Cdd:COG3883    89 GERARALYRSGGsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAK-----LAELEALK 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  901 QELEQAKFEMQERMAKQEEKYqNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 957
Cdd:COG3883   164 AELEAAKAELEAQQAEQEALL-AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219

OmpH

pfam03938

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

832-932

3.51e-03

Pssm-ID: 461098 [Multi-domain] Cd Length: 140 Bit Score: 39.10 E-value: 3.51e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   832 DREAIIEK--ERTAIRERFER---QLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEaLREQEQELEQa 906
Cdd:pfam03938    6 DMQKILEEspEGKAAQAQLEKkfkKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQE-LQQLQQKAQQ- 83

                           90       100
                   ....*....|....*....|....*.
gi 386767625   907 kfEMQERMAKQEEKYQNRVNTIEQQY 932
Cdd:pfam03938   84 --ELQKKQQELLQPIQDKINKAIKEV 107

PRK12705

hypothetical protein; Provisional

862-998

4.25e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.23 E-value: 4.25e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  862 QRQKLTEEFAAERDRLQSELRQRENEHQARRQEAL-REQEQELEQAKFEMQE------RMAKQEEKYQNRVNTIEQQYQA 934
Cdd:PRK12705   27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLlRERNQQRQEARREREElqreeeRLVQKEEQLDARAEKLDNLENQ 106

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  935 DFELWKTEHENKTKLAQAEKENAiRQHYRA---ERDRQLDELVVRMEADAlqhKEEHELKMNRLKEK 998
Cdd:PRK12705  107 LEEREKALSARELELEELEKQLD-NELYRVaglTPEQARKLLLKLLDAEL---EEEKAQRVKKIEEE 169

HlpA

COG2825

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...

830-906

4.33e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 39.43 E-value: 4.33e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  830 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQA 906
Cdd:COG2825    52 FKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQELLQPILEKIQKA 128

PRK09039

peptidoglycan -binding protein;

777-927

4.50e-03

peptidoglycan -binding protein;

Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.72 E-value: 4.50e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  777 TVKGLEAEINKMNcdhqREVTELKrthqmQLLdALEEARTkheqieTSIRESCAQDREAIIEKErtAIRERFERQLEE-- 854
Cdd:PRK09039   47 EISGKDSALDRLN----SQIAELA-----DLL-SLERQGN------QDLQDSVANLRASLSAAE--AERSRLQALLAEla 108

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767625  855 EQRTQAEQR-QKLTEEFAAERDRLQSELRQRENEHQarRQEALREQEQELEQAKFEMQERMAKQEEKYQ---NRVNT 927
Cdd:PRK09039  109 GAGAAAEGRaGELAQELDSEKQVSARALAQVELLNQ--QIAALRRQLAALEAALDASEKRDRESQAKIAdlgRRLNV 183

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

715-1123

4.77e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 40.89 E-value: 4.77e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   715 LKDKGSLCEKVAALTRRLESQnqaweHRLETELARTKETTMAgEKIRRERWVRE-----NTKKIKELTVKGLE-----AE 784
Cdd:pfam07111   55 LEGSQALSQQAELISRQLQEL-----RRLEEEVRLLRETSLQ-QKMRLEAQAMEldalaVAEKAGQAEAEGLRaalagAE 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   785 INKMNCDH--QREVTELKRTHQMQlLDALEEArtkHEQIETSIrescaqdreaiiekerTAIRERFERQLEE-EQRTQAE 861
Cdd:pfam07111  129 MVRKNLEEgsQRELEEIQRLHQEQ-LSSLTQA---HEEALSSL----------------TSKAEGLEKSLNSlETKRAGE 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   862 QRQKLTEEFAAERDRLQSELRQRENEHQARRQEALRE------------QEQELEQAK-FEMQERMAKQEEKYQNRVNTI 928
Cdd:pfam07111  189 AKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKyvgeqvppevhsQTWELERQElLDTMQHLQEDRADLQATVELL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   929 EQQYQADFELWKTEHENKTKLAQ------AEKENAIRQHYRAERDRQLdELVVRMEADALQHKEEHELKMNRLKEKYEKd 1002
Cdd:pfam07111  269 QVRVQSLTHMLALQEEELTRKIQpsdslePEFPKKCRSLLNRWREKVF-ALMVQLKAQDLEHRDSVKQLRGQVAELQEQ- 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1003 lVLAESVEKSLREKyaetrgKLAEADAQVRNSQAEVKQLQLELSHSKkmcgdiimERDRLRDNLNADIQSELGVLnerhK 1082
Cdd:pfam07111  347 -VTSQSQEQAILQR------ALQDKAAEVEVERMSAKGLQMELSRAQ--------EARRRQQQQTASAEEQLKFV----V 407

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 386767625  1083 QEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAV 1123
Cdd:pfam07111  408 NAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTI 448

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

677-1128

4.94e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.31 E-value: 4.94e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVtrhqGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhrletELARTKEttma 756
Cdd:pfam01576  510 EAKRNVERQLSTLQAQLSDMKKKLEEDA----GTLEALEEGKKRLQRELEALTQQLEEKAAAYD-----KLEKTKN---- 576

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   757 geKIRRErwvrentkkIKELTVkgleaeinkmNCDHQRevtelkrthqmQLLDALEEARTKHEQI---ETSIRESCAQDR 833
Cdd:pfam01576  577 --RLQQE---------LDDLLV----------DLDHQR-----------QLVSNLEKKQKKFDQMlaeEKAISARYAEER 624

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   834 EAI----IEKERTAIRerFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRqeALREQEQELEQAKFE 909
Cdd:pfam01576  625 DRAeaeaREKETRALS--LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELER--SKRALEQQVEEMKTQ 700

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   910 MQER----MAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnaIRQHyRAERDrqlDELVVRMEADALQHK 985
Cdd:pfam01576  701 LEELedelQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQ--VREL-EAELE---DERKQRAQAVAAKKK 774

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   986 EEHELK--------MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNS-------QAEVKQLQLELSHSKK 1050
Cdd:pfam01576  775 LELDLKeleaqidaANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESekklknlEAELLQLQEDLAASER 854

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1051 MCGDIIMERDRLRDNLNADIQSELGVLNERHkqemdQLQKRVHQTIQRQEE---TIEILKGDNDALRQQCLKLNAVIRQQ 1127
Cdd:pfam01576  855 ARRQAQQERDELADEIASGASGKSALQDEKR-----RLEARIAQLEEELEEeqsNTELLNDRLRKSTLQVEQLTTELAAE 929


                   .
gi 386767625  1128 R 1128
Cdd:pfam01576  930 R 930

rne

PRK10811

ribonuclease E; Reviewed

845-933

5.15e-03

ribonuclease E; Reviewed

Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 5.15e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  845 RERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQEleqAKFEMQERMAKQEEKYQNR 924
Cdd:PRK10811  636 REENRRNRRQAQQQTAETRESQQAEVTEKARTQDEQQQAPRRERQRRRNDEKRQAQQE---AKALNVEEQSVQETEQEER 712


                  ....*....
gi 386767625  925 VNTIEQQYQ 933
Cdd:PRK10811  713 VQQVQPRRK 721

PRK03918

DNA double-strand break repair ATPase Rad50;

833-1129

5.23e-03

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 40.82 E-value: 5.23e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  833 REAIIEKERTAIRERFERQLEEEQRTQAEQRqKLTEEFAAERDRLQSELRQRENEHQARRQEALREQE-QELEQAKFEMQ 911
Cdd:PRK03918  187 RTENIEELIKEKEKELEEVLREINEISSELP-ELREELEKLEKEVKELEELKEEIEELEKELESLEGSkRKLEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  912 ERMAKQEEKYQN------RVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHK 985
Cdd:PRK03918  266 ERIEELKKEIEEleekvkELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  986 EEHEL--KMNRLKEK---YEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVkqlQLELSHSKKMCGDIIMERD 1060
Cdd:PRK03918  346 KLKELekRLEELEERhelYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEI---EEEISKITARIGELKKEIK 422

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767625 1061 RLRDNLNAdIQSELGV-------LNERHKQEmdqLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRK 1129
Cdd:PRK03918  423 ELKKAIEE-LKKAKGKcpvcgreLTEEHRKE---LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

RNase_Y_N

pfam12072

RNase Y N-terminal region;

799-920

5.28e-03

RNase Y N-terminal region;

Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 39.48 E-value: 5.28e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   799 LKRTHQMQLLDALEEARtkhEQIETSIRESCAQDREAIIEK--ERTAIRERFERQLEEEQR-TQAEQRQKLTEEfaAERD 875
Cdd:pfam12072   21 RKSIAEAKIGSAEELAK---RIIEEAKKEAETKKKEALLEAkeEIHKLRAEAERELKERRNeLQRQERRLLQKE--ETLD 95

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 386767625   876 RLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEEK 920
Cdd:pfam12072   96 RKDESLEKKEESLEKKEKE-LEAQQQQLEEKEEELEELIEEQRQE 139

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

677-920

5.31e-03

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 5.31e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   677 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKdkgsLCEKVAALTRRLesqNQAWEHRLETELARTKETTMa 756
Cdd:pfam07888  171 AERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQ----LQDTITTLTQKL---TTAHRKEAENEALLEELRSL- 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   757 gekirRERWVrentkkIKELTVKGLEAEINKMNCDHQREVTELKRTH------QMQLLD---ALEEARTKHEQIETSIRE 827
Cdd:pfam07888  243 -----QERLN------ASERKVEGLGEELSSMAAQRDRTQAELHQARlqaaqlTLQLADaslALREGRARWAQERETLQQ 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   828 SCAQDREAIiEKERTAIrERFERQLEEEQRtqaeQRQKLTEEFAAERD--RLQ-SELRQRENEHQARRQEALREQEQELE 904
Cdd:pfam07888  312 SAEADKDRI-EKLSAEL-QRLEERLQEERM----EREKLEVELGREKDcnRVQlSESRRELQELKASLRVAQKEKEQLQA 385

                          250
                   ....*....|....*.
gi 386767625   905 QaKFEMQERMAKQEEK 920
Cdd:pfam07888  386 E-KQELLEYIRQLEQR 400

PHA02562

endonuclease subunit; Provisional

850-1062

5.95e-03

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 40.77 E-value: 5.95e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  850 RQLEEEQRTQAEQRQKLTEEFAAERDrLQSELRQRENEHQARRQ---EALREQEQELEQAKFEMQERMA---KQEEKYQN 923
Cdd:PHA02562  177 RELNQQIQTLDMKIDHIQQQIKTYNK-NIEEQRKKNGENIARKQnkyDELVEEAKTIKAEIEELTDELLnlvMDIEDPSA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  924 RVNTIEQ----------QYQADFELWKTEHENKTKLAQ-----------AEKENAIRQHYRAERDRQlDELVVRMEADAL 982
Cdd:PHA02562  256 ALNKLNTaaakikskieQFQKVIKMYEKGGVCPTCTQQisegpdritkiKDKLKELQHSLEKLDTAI-DELEEIMDEFNE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  983 QHKEEHELKMNRLKEKYEkdlvLAESVEKSLREKYAetrgkLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRL 1062
Cdd:PHA02562  335 QSKKLLELKNKISTNKQS----LITLVDKAKKVKAA-----IEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR 405

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

661-1062

6.55e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.80 E-value: 6.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   661 ANAIHMSKEHVFQLRgEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRhqgfiEQLLKDkgslCEKVAALTRRLESQNQAWE 740
Cdd:TIGR00606  736 QSIIDLKEKEIPELR-NKLQKVNRDIQRLKNDIEEQETLLGTIMPE-----EESAKV----CLTDVTIMERFQMELKDVE 805

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   741 HRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGleAEINKMNCDHQREVTELK------RTHQMQLLDALEEA 814
Cdd:TIGR00606  806 RKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI--ELNRKLIQDQQEQIQHLKsktnelKSEKLQIGTNLQRR 883

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   815 RTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQR-------ENE 887
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIhgymkdiENK 963

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   888 HQARRQEALREQEQELEQAKFEMQErmakqEEKYQNRVNTIEQQYQADFELWKT-EHENKTKLAQAEKENAIRQ--HYRA 964
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTVNAQLEE-----CEKHQEKINEDMRLMRQDIDTQKIqERWLQDNLTLRKRENELKEveEELK 1038

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   965 ERDRQLDELVVrmeadaLQHKEEHelkmNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEAD---AQVRNSQAEVKQL 1041
Cdd:TIGR00606 1039 QHLKEMGQMQV------LQMKQEH----QKLEE--NIDLIKRNHVLALGRQKGYEKEIKHFKKElrePQFRDAEEKYREM 1106

                          410       420
                   ....*....|....*....|.
gi 386767625  1042 QLELSHSKKMCGDIIMERDRL 1062
Cdd:TIGR00606 1107 MIVMRTTELVNKDLDIYYKTL 1127

PRK11281

mechanosensitive channel MscK;

975-1129

6.66e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 6.66e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  975 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLqlelshsKKMCGD 1054
Cdd:PRK11281   41 VQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQ-KEETEQLKQQLAQAPAKLRQAQAELEAL-------KDDNDE 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625 1055 IIMER------DRLRDNLN------ADIQSELGVLN----------ERHKQEMDQLQKRVhQTIQRQEETIEILKGDNDA 1112
Cdd:PRK11281  113 ETRETlstlslRQLESRLAqtldqlQNAQNDLAEYNsqlvslqtqpERAQAALYANSQRL-QQIRNLLKGGKVGGKALRP 191

                         170       180
                  ....*....|....*....|..
gi 386767625 1113 LRQQCLK-----LNAVIRQQRK 1129
Cdd:PRK11281  192 SQRVLLQaeqalLNAQNDLQRK 213

CusB_dom_1

pfam00529

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...

870-1048

7.34e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.

Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 39.71 E-value: 7.34e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   870 FAAERDRLQSELRQreNEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQnRVNTIEQQYQADFELWKTEHENKTKL 949
Cdd:pfam00529   56 YQAALDSAEAQLAK--AQAQVARLQAELDRLQALESELAISRQDYDGATAQLR-AAQAAVKAAQAQLAQAQIDLARRRVL 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   950 AqaeKENAIRQhyraerdRQLDELvvRMEADALQHkeehelkmNRLKEKYEKDLVLAEsVEKSLREKYAETRGKLAEADA 1029
Cdd:pfam00529  133 A---PIGGISR-------ESLVTA--GALVAQAQA--------NLLATVAQLDQIYVQ-ITQSAAENQAEVRSELSGAQL 191

                          170
                   ....*....|....*....
gi 386767625  1030 QVRNSQAEVKQLQLELSHS 1048
Cdd:pfam00529  192 QIAEAEAELKLAKLDLERT 210

CCCAP

pfam15964

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...

800-1119

7.60e-03

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.

Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 40.27 E-value: 7.60e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   800 KRTHQMQLLDALEEARTKHEQIETSIRESCAQ----DREAIIEKERTAI------------RERFERQLEEEQRTQAEQR 863
Cdd:pfam15964  308 ERDDLMSALVSVRSSLAEAQQRESSAYEQVKQavqmTEEANFEKTKALIqceqlkselerqKERLEKELASQQEKRAQEK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   864 QKLTEEFAAERDRLQSE---LRQRENEHQARRQEALREQEQELEQAKfEMQERMAKQEEKYQNRVNtiEQQYQAdfelwk 940
Cdd:pfam15964  388 EALRKEMKKEREELGATmlaLSQNVAQLEAQVEKVTREKNSLVSQLE-EAQKQLASQEMDVTKVCG--EMRYQL------ 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625   941 teheNKTKLAQAEKENAIRQhYRAERDRQL---DELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLR--- 1014
Cdd:pfam15964  459 ----NQTKMKKDEAEKEHRE-YRTKTGRQLeikDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHqlh 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  1015 ----EKYAETRGKLAEADAQVRNSQAEVKQL-----QLELSHSKKmcgdiIMERDRLRDNLN---ADIQSELGVLNERHK 1082
Cdd:pfam15964  534 ltrlEKESIQQSFSNEAKAQALQAQQREQELtqkmqQMEAQHDKT-----VNEQYSLLTSQNtfiAKLKEECCTLAKKLE 608

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 386767625  1083 QEMDQLQKRVHQTIQRQE---ETIEILKGDNDALRQQCLK 1119
Cdd:pfam15964  609 EITQKSRSEVEQLSQEKEylqDRLEKLQKRNEELEEQCVQ 648

PRK10929

putative mechanosensitive channel protein; Provisional

791-938

8.04e-03

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 40.42 E-value: 8.04e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  791 DHQREVTE-LKRTHQMQlldalEEARTKHEQIETSIR------ESCAQDREAIIEKERTAIRERFErQLEEEQRTqAEQR 863
Cdd:PRK10929  130 DRAREISDsLSQLPQQQ-----TEARRQLNEIERRLQtlgtpnTPLAQAQLTALQAESAALKALVD-ELELAQLS-ANNR 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  864 QKLTeefaaerdRLQSELRQRENEHQARRQEALREQ-----EQELEQAkFEMQERMAKQEEkyqNRVNTIEQQYQADFEL 938
Cdd:PRK10929  203 QELA--------RLRSELAKKRSQQLDAYLQALRNQlnsqrQREAERA-LESTELLAEQSG---DLPKSIVAQFKINREL 270

PRK10920

putative uroporphyrinogen III C-methyltransferase; Provisional

861-953

9.15e-03

putative uroporphyrinogen III C-methyltransferase; Provisional

Pssm-ID: 236795 Cd Length: 390 Bit Score: 39.69 E-value: 9.15e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767625  861 EQRQKLTEEFAAERDRLqSELRQRENEHQARRQEALREQEQELEQAKFEmQERMAKQEEKYQNRVNTIEqqyQADFELWk 940
Cdd:PRK10920   60 QQAQNQTATNDALANQL-TALQKAQESQKQELEGILKQQAKALDQANRQ-QAALAKQLDELQQKVATIS---GSDAKTW- 133

                          90
                  ....*....|...
gi 386767625  941 tehenktKLAQAE 953
Cdd:PRK10920  134 -------LLAQAD 139

DUF4670