|
Name |
Accession |
Description |
Interval |
E-value |
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
80-726 |
0e+00 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 771.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 80 RTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQCDITSKKNLELQDDLKALRKRElVLKNEASRATAELNQ 159
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKRE-AEAEEALREQAELNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 160 LRLKFDESTLKLQKEKYLQKEDARDVHLCINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHE 239
Cdd:pfam05557 80 LKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 240 KQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLER 319
Cdd:pfam05557 160 KQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLER 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 320 EEGARAEAASLQVKLLHMEQELKEWVKVAQDHCLanTLVSPMALRSRIEQLLKEDIIHVAEKTSSASDTKHLNTTIRDLE 399
Cdd:pfam05557 240 EEKYREEAATLELEKEKLEQELQSWVKLAQDTGL--NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 400 HKCAIYLKNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFDKDTTLSNAS---------VADMTQDMQ---- 466
Cdd:pfam05557 318 QELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSpqllerieeAEDMTQKMQahne 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 467 -VRVRMEVLERTVTGYKDMCATLEREIQSLRQQELVNEP--AGEGYDSVKKELDTLRMENDRLRRRKEELEMEMMHRCLR 543
Cdd:pfam05557 398 eMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPsySKEEVDSLRRKLETLELERQRLREQKNELEMELERRCLQ 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 544 GDFNMKDFKVVHFSENPAAEAYESTKNMMEKLQAEIERLKRRNKKLEDDNEQ--RLNETTStggmTLNFKEFNQLQAELE 621
Cdd:pfam05557 478 GDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQvlRLPETTS----TMNFKEVLDLRKELE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 622 SANGKMRKMRDCFKAAREEFRDVCYMLLGYRIDrIGANSNYRISSMFAEGPDDYLDISLNESNC--LALLESPYSHTFNP 699
Cdd:pfam05557 554 SAELKNQRLKEVFQAKIQEFRDVCYMLTGYQID-ITTNSQYRLTSMYAEHPDDYLLFKLSGSNGstMQLLETPFSRTLEP 632
|
650 660
....*....|....*....|....*...
gi 24652071 700 PIDQQLAASN-FPAFFSALTLELFQKAT 726
Cdd:pfam05557 633 LIDLHLAAQKsIPAFLSALTLELFSRQT 660
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
85-370 |
6.20e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 6.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 85 ETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDqcdiTSKKNLELQDDLKALRKREL-------VLKNEASRATAEL 157
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEelsrqisALRKDLARLEAEV 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 158 NQL-----RLKFDESTLKLQKEKYLQK-EDARDVHLCINNELSEYRRIAQRADLELQSTRNEL----ERLRQLNEELQAR 227
Cdd:TIGR02168 743 EQLeeriaQLSKELTELEAEIEELEERlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALdelrAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 228 ASGFEQLRANHEKQTQSLKVANDRIQELEFEIQSYS------------------DWKEVVKTSRERLASVPDLLAEVEH- 288
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAaeieeleelieeleseleALLNERASLEEALALLRSELEELSEe 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 289 LRSHNKHLNTLIGDKLLLEEQVYDYKTRLEReegaraeaasLQVKLLHMEQELKEWVKVAQDHCLANTLV---SPMALRS 365
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKLAQLELRLEG----------LEVRIDNLQERLSEEYSLTLEEAEALENKiedDEEEARR 972
|
....*
gi 24652071 366 RIEQL 370
Cdd:TIGR02168 973 RLKRL 977
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
99-373 |
3.57e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 3.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 99 KKSREHKEAILLAENKSTALKDqcDITSKKNLELQDDLKALRKRELVLKNEASRATAELNQLRLKFDESTLKLQKekyLQ 178
Cdd:COG1196 213 ERYRELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE---AQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 179 KEDARdvhlcINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFE 258
Cdd:COG1196 288 AEEYE-----LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 259 IQsysdwKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEGARAEAASLQVKLLHME 338
Cdd:COG1196 363 AE-----EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437
|
250 260 270
....*....|....*....|....*....|....*
gi 24652071 339 QELKEWVKVAQDHcLANTLVSPMALRSRIEQLLKE 373
Cdd:COG1196 438 EEEEEALEEAAEE-EAELEEEEEALLELLAELLEE 471
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
173-591 |
8.63e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 8.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 173 KEKYLQKEDarDVHLCINNELSEYRRIAQRADL---ELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVAN 249
Cdd:PRK03918 181 LEKFIKRTE--NIEELIKEKEKELEEVLREINEissELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 250 DRIQELEfeiqsysdwkEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEGARAEAAS 329
Cdd:PRK03918 259 EKIRELE----------ERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 330 LQVKLLHMEQELKEwvkvaqdhclantlvspmaLRSRIEQLLKEdIIHVAEKTSSASDTKHLNTTIRDLEHKCAIYlkNI 409
Cdd:PRK03918 329 RIKELEEKEERLEE-------------------LKKKLKELEKR-LEELEERHELYEEAKAKKEELERLKKRLTGL--TP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 410 EDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVEnfdkdttlsnasvadmtqdmQVRVRMEVLErtvtGYKDMCATLE 489
Cdd:PRK03918 387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIK--------------------ELKKAIEELK----KAKGKCPVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 490 REIQSLRQQELVNEPAGEgYDSVKKELDTLRMENDRLRRRKEELEMEMM-HRCLRGDFNMKDF--------KVVHFSE-N 559
Cdd:PRK03918 443 RELTEEHRKELLEEYTAE-LKRIEKELKEIEEKERKLRKELRELEKVLKkESELIKLKELAEQlkeleeklKKYNLEElE 521
|
410 420 430
....*....|....*....|....*....|..
gi 24652071 560 PAAEAYESTKNMMEKLQAEIERLKRRNKKLED 591
Cdd:PRK03918 522 KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
80-726 |
0e+00 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 771.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 80 RTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQCDITSKKNLELQDDLKALRKRElVLKNEASRATAELNQ 159
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKRE-AEAEEALREQAELNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 160 LRLKFDESTLKLQKEKYLQKEDARDVHLCINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHE 239
Cdd:pfam05557 80 LKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 240 KQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLER 319
Cdd:pfam05557 160 KQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLER 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 320 EEGARAEAASLQVKLLHMEQELKEWVKVAQDHCLanTLVSPMALRSRIEQLLKEDIIHVAEKTSSASDTKHLNTTIRDLE 399
Cdd:pfam05557 240 EEKYREEAATLELEKEKLEQELQSWVKLAQDTGL--NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 400 HKCAIYLKNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFDKDTTLSNAS---------VADMTQDMQ---- 466
Cdd:pfam05557 318 QELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSpqllerieeAEDMTQKMQahne 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 467 -VRVRMEVLERTVTGYKDMCATLEREIQSLRQQELVNEP--AGEGYDSVKKELDTLRMENDRLRRRKEELEMEMMHRCLR 543
Cdd:pfam05557 398 eMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPsySKEEVDSLRRKLETLELERQRLREQKNELEMELERRCLQ 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 544 GDFNMKDFKVVHFSENPAAEAYESTKNMMEKLQAEIERLKRRNKKLEDDNEQ--RLNETTStggmTLNFKEFNQLQAELE 621
Cdd:pfam05557 478 GDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQvlRLPETTS----TMNFKEVLDLRKELE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 622 SANGKMRKMRDCFKAAREEFRDVCYMLLGYRIDrIGANSNYRISSMFAEGPDDYLDISLNESNC--LALLESPYSHTFNP 699
Cdd:pfam05557 554 SAELKNQRLKEVFQAKIQEFRDVCYMLTGYQID-ITTNSQYRLTSMYAEHPDDYLLFKLSGSNGstMQLLETPFSRTLEP 632
|
650 660
....*....|....*....|....*...
gi 24652071 700 PIDQQLAASN-FPAFFSALTLELFQKAT 726
Cdd:pfam05557 633 LIDLHLAAQKsIPAFLSALTLELFSRQT 660
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
85-370 |
6.20e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 6.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 85 ETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDqcdiTSKKNLELQDDLKALRKREL-------VLKNEASRATAEL 157
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEelsrqisALRKDLARLEAEV 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 158 NQL-----RLKFDESTLKLQKEKYLQK-EDARDVHLCINNELSEYRRIAQRADLELQSTRNEL----ERLRQLNEELQAR 227
Cdd:TIGR02168 743 EQLeeriaQLSKELTELEAEIEELEERlEEAEEELAEAEAEIEELEAQIEQLKEELKALREALdelrAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 228 ASGFEQLRANHEKQTQSLKVANDRIQELEFEIQSYS------------------DWKEVVKTSRERLASVPDLLAEVEH- 288
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAaeieeleelieeleseleALLNERASLEEALALLRSELEELSEe 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 289 LRSHNKHLNTLIGDKLLLEEQVYDYKTRLEReegaraeaasLQVKLLHMEQELKEWVKVAQDHCLANTLV---SPMALRS 365
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKLAQLELRLEG----------LEVRIDNLQERLSEEYSLTLEEAEALENKiedDEEEARR 972
|
....*
gi 24652071 366 RIEQL 370
Cdd:TIGR02168 973 RLKRL 977
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
56-632 |
2.46e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 54.35 E-value: 2.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 56 LNDTASSLNMPANDSMASL---------QNSKLRTELIETKAIVIQLRNEIEKKSREHKEAI-------LLAENKSTALK 119
Cdd:pfam15921 283 LTEKASSARSQANSIQSQLeiiqeqarnQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIeelekqlVLANSELTEAR 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 120 DQCDITSKKNLELQDDLKAL------RKRELVLKNEASRA--------TAELNQLRLKFDESTLKLQKEKYLQKEDArdv 185
Cdd:pfam15921 363 TERDQFSQESGNLDDQLQKLladlhkREKELSLEKEQNKRlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLKAMK--- 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 186 hlcinnelSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFEIQSYSDW 265
Cdd:pfam15921 440 --------SECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERA 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 266 KEVVKTSRERLASVPDL-LAEVEHLRSHNKHLntligdkllleeqvydyktrleREEGARAEAASLQV----KLLH-MEQ 339
Cdd:pfam15921 512 IEATNAEITKLRSRVDLkLQELQHLKNEGDHL----------------------RNVQTECEALKLQMaekdKVIEiLRQ 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 340 ELKEWVKVAQDHclANTLVSPMALRSRIEQLLKEDIIHVAE----KTSSASDTKHLNTTIRDLEhkcaiyLKNIEDLNIG 415
Cdd:pfam15921 570 QIENMTQLVGQH--GRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRELEARVSDLE------LEKVKLVNAG 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 416 LKRHKNFKErlqrklitVSKERDFYKQLVENfdkdttlSNASVADMTQDMQV-----RVRMEVLERTVTGYKDMCATLER 490
Cdd:pfam15921 642 SERLRAVKD--------IKQERDQLLNEVKT-------SRNELNSLSEDYEVlkrnfRNKSEEMETTTNKLKMQLKSAQS 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 491 EIQ----SLRQQELVNEPAGEGYDSVKKELDTLRMENDRLRRRKEELEMEMMHRCLRGDFnMKDFKvvhfseNPAAEAYE 566
Cdd:pfam15921 707 ELEqtrnTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEK------NKLSQELS 779
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24652071 567 STKNMMEKLQAEIERLKRRNKKLEddnEQRLNETTSTGGMTLNFKEFNQL--QAELESANGKMRKMRD 632
Cdd:pfam15921 780 TVATEKNKMAGELEVLRSQERRLK---EKVANMEVALDKASLQFAECQDIiqRQEQESVRLKLQHTLD 844
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
99-373 |
3.57e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 3.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 99 KKSREHKEAILLAENKSTALKDqcDITSKKNLELQDDLKALRKRELVLKNEASRATAELNQLRLKFDESTLKLQKekyLQ 178
Cdd:COG1196 213 ERYRELKEELKELEAELLLLKL--RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE---AQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 179 KEDARdvhlcINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFE 258
Cdd:COG1196 288 AEEYE-----LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 259 IQsysdwKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEGARAEAASLQVKLLHME 338
Cdd:COG1196 363 AE-----EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437
|
250 260 270
....*....|....*....|....*....|....*
gi 24652071 339 QELKEWVKVAQDHcLANTLVSPMALRSRIEQLLKE 373
Cdd:COG1196 438 EEEEEALEEAAEE-EAELEEEEEALLELLAELLEE 471
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-644 |
1.01e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 75 QNSKLRTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQcditSKKNLELQDDLKALRKRELVLKNEASRAT 154
Cdd:TIGR02168 331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL----EEQLETLRSKVAQLELQIASLNNEIERLE 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 155 AELNQL---RLKFDESTLKLQKEkyLQKEDARDVHLcinnELSEYRRIAQRADLELQSTRNELERLRQLNEE-------- 223
Cdd:TIGR02168 407 ARLERLedrRERLQQEIEELLKK--LEEAELKELQA----ELEELEEELEELQEELERLEEALEELREELEEaeqaldaa 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 224 ------LQARASGFEQLRANHEKQTQSLK--VAN--------DRIQELefeIQSYSDW-KEVVKTSRERLASV-----PD 281
Cdd:TIGR02168 481 erelaqLQARLDSLERLQENLEGFSEGVKalLKNqsglsgilGVLSEL---ISVDEGYeAAIEAALGGRLQAVvvenlNA 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 282 LLAEVEHLRSHNKHLNT-LIGDKLLLEEQVYDYKTRLEREEGARAEAASLQVKLLHMEQELKEW---VKVAQDHCLANTL 357
Cdd:TIGR02168 558 AKKAIAFLKQNELGRVTfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggVLVVDDLDNALEL 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 358 VSPMALRSRI-----EQLLKEDIIHVAEKTSSASDTkHLNTTIRDLEHKCAIYLKNIEDLNIGLKRHKNFKERLQRKLIT 432
Cdd:TIGR02168 638 AKKLRPGYRIvtldgDLVRPGGVITGGSAKTNSSIL-ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ 716
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 433 VSKERDFYKQLVENFDKDTTLSNASVAdmtqdmQVRVRMEVLERTVTGYKDMCATLEREIQSLRQQELVNEpagEGYDSV 512
Cdd:TIGR02168 717 LRKELEELSRQISALRKDLARLEAEVE------QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE---AEIEEL 787
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 513 KKELDTLRMENDRLRRRKEELEMEmmHRCLRGDFNMKDFKV------VHFSENPAAEAYESTKNM---MEKLQAEIERLK 583
Cdd:TIGR02168 788 EAQIEQLKEELKALREALDELRAE--LTLLNEEAANLRERLeslerrIAATERRLEDLEEQIEELsedIESLAAEIEELE 865
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24652071 584 RRNKKLEDDNEQRLNETTSTG-GMTLNFKEFNQLQAELESANGKMRKMRDCFKAAREEFRDV 644
Cdd:TIGR02168 866 ELIEELESELEALLNERASLEeALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
72-600 |
1.05e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.25 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 72 ASLQNSKLRTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQcditSKKNLELQDDLKALRKRELVLKNEAS 151
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA----EAELAEAEEELEELAEELLEALRAAA 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 152 RATAELNQLRlkfdestlklQKEKYLQKEDARdvhlcINNELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASGF 231
Cdd:COG1196 397 ELAAQLEELE----------EAEEALLERLER-----LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 232 EQLRANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVY 311
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 312 DY-------KTRLEREEGARAEAASLQVKLLHMEQELKEWVKVAQDHCLANTLVSPMALRSRIEQLLKED-------IIH 377
Cdd:COG1196 542 AAlaaalqnIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAdaryyvlGDT 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 378 VAEKTSSASDTKHLNTTIRDLEHKCAIYLKNIEDLNIG--------LKRHKNFKERLQRKLITVSKERDFYKQLVENFDK 449
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGgsltggsrRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 450 DTTLSNASVADMTQDMQVRVRMEVLERTVTgykdmcATLEREIQSLRQQELVNEPAGEGYDSVKKELDTLRMENDRLRRR 529
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLE------AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24652071 530 KEELememmhrclrGDFNMKdfkvvhfsenpAAEAYESTKN----MMEK---LQAEIERLKRRNKKLEDDNEQRLNET 600
Cdd:COG1196 776 IEAL----------GPVNLL-----------AIEEYEELEErydfLSEQredLEEARETLEEAIEEIDRETRERFLET 832
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
92-343 |
2.33e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 92 QLRNEIEKKSREHKEAILLAENKSTALkdqcDITSKKNLELQDDLKALRKRELVLKNEASRATAELNQL--RLKFDESTL 169
Cdd:TIGR02168 243 ELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILreRLANLERQL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 170 KlQKEKYLQKEDARdvhlcinneLSEYRRIAQRADLELQSTRNELERLRQ----LNEELQARASGFEQLRANHEKQTQSL 245
Cdd:TIGR02168 319 E-ELEAQLEELESK---------LDELAEELAELEEKLEELKEELESLEAeleeLEAELEELESRLEELEEQLETLRSKV 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 246 KVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEGARA 325
Cdd:TIGR02168 389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468
|
250
....*....|....*...
gi 24652071 326 EAASLQVKLLHMEQELKE 343
Cdd:TIGR02168 469 ELEEAEQALDAAERELAQ 486
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
85-542 |
1.13e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.81 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 85 ETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQCDITSKKNLELQDDLKALR------KRELVLKNEASRATAELN 158
Cdd:TIGR00618 184 MEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQqshaylTQKREAQEEQLKKQQLLK 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 159 QLRLKFDESTLKLQKEKYLQKEDARDVH----LCINNELSEYRRIAQRADLELQSTRNELERLRQLneelqarasgfeql 234
Cdd:TIGR00618 264 QLRARIEELRAQEAVLEETQERINRARKaaplAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMK-------------- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 235 RANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVpdlLAEVEHLRSHNKHLNTLIgDKLLLEEQVYDYK 314
Cdd:TIGR00618 330 RAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQ---HTLTQHIHTLQQQKTTLT-QKLQSLCKELDIL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 315 TRLEREEGAR-AEAASLQVKLLHMEQELKEWVKVAQdhclantlvspmALRSRIEQLLKEDIIHVAEKTSSASDTKHLNT 393
Cdd:TIGR00618 406 QREQATIDTRtSAFRDLQGQLAHAKKQQELQQRYAE------------LCAAAITCTAQCEKLEKIHLQESAQSLKEREQ 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 394 TIRDLEhkcaiylkniedlNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFDKDTTLSNASVadmtqdmqVRVRMEV 473
Cdd:TIGR00618 474 QLQTKE-------------QIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGP--------LTRRMQR 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 474 LERTVTGYKDMCATLEREIQSLRQQ--ELVNEPAGEGYD---------SVKKELDTLRMENDRLRRR-KEELEMEMMHRC 541
Cdd:TIGR00618 533 GEQTYAQLETSEEDVYHQLTSERKQraSLKEQMQEIQQSfsiltqcdnRSKEDIPNLQNITVRLQDLtEKLSEAEDMLAC 612
|
.
gi 24652071 542 L 542
Cdd:TIGR00618 613 E 613
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
168-468 |
1.66e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.39 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 168 TLKLQKEK------YLQKEDARDVHLCINnELSEYRRIAQRADLELQSTRNELERLrqlNEELQARASGFEQLRANHEKQ 241
Cdd:COG1196 204 PLERQAEKaeryreLKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEEL---EAELAELEAELEELRLELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 242 TQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASvpDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREE 321
Cdd:COG1196 280 ELELEEAQAEEYELLAELARLEQDIARLEERRRELEE--RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 322 GARAEAASLQVKLLH-MEQELKEWVKVAQDhcLANTLVSPMALRSRIEQLLKEDIIHVAEKTSSASDTKHLNTTIRDLEH 400
Cdd:COG1196 358 AELAEAEEALLEAEAeLAEAEEELEELAEE--LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24652071 401 KCAIYLKNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENfDKDTTLSNASVADMTQDMQVR 468
Cdd:COG1196 436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLEELAEAAARLLLLLEAEAD 502
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
72-285 |
3.12e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 72 ASLQNSKLRTELIETKAIVIQLRNEIEKKSREHKEAillaENKSTALKDQCDITSKKNLELQDDLKALRKRELVLKNEAS 151
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKAL----LKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 152 RATAELNQLRLKFDESTLKLQK-------EKYLQKEDARDvhlcINNELSEYRRIAQRADLELQSTRNELERLRQLNEEL 224
Cdd:COG4942 94 ELRAELEAQKEELAELLRALYRlgrqpplALLLSPEDFLD----AVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 24652071 225 QARASGFEQLRANHEKQTQSLKVA----NDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAE 285
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALkaerQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
173-591 |
8.63e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 8.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 173 KEKYLQKEDarDVHLCINNELSEYRRIAQRADL---ELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVAN 249
Cdd:PRK03918 181 LEKFIKRTE--NIEELIKEKEKELEEVLREINEissELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 250 DRIQELEfeiqsysdwkEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEGARAEAAS 329
Cdd:PRK03918 259 EKIRELE----------ERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 330 LQVKLLHMEQELKEwvkvaqdhclantlvspmaLRSRIEQLLKEdIIHVAEKTSSASDTKHLNTTIRDLEHKCAIYlkNI 409
Cdd:PRK03918 329 RIKELEEKEERLEE-------------------LKKKLKELEKR-LEELEERHELYEEAKAKKEELERLKKRLTGL--TP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 410 EDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVEnfdkdttlsnasvadmtqdmQVRVRMEVLErtvtGYKDMCATLE 489
Cdd:PRK03918 387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIK--------------------ELKKAIEELK----KAKGKCPVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 490 REIQSLRQQELVNEPAGEgYDSVKKELDTLRMENDRLRRRKEELEMEMM-HRCLRGDFNMKDF--------KVVHFSE-N 559
Cdd:PRK03918 443 RELTEEHRKELLEEYTAE-LKRIEKELKEIEEKERKLRKELRELEKVLKkESELIKLKELAEQlkeleeklKKYNLEElE 521
|
410 420 430
....*....|....*....|....*....|..
gi 24652071 560 PAAEAYESTKNMMEKLQAEIERLKRRNKKLED 591
Cdd:PRK03918 522 KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
130-534 |
8.69e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 8.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 130 LELQDDLKALRKRELVLKNEASRATAELNQLRLKFDEstlkLQKEKYLQKEDARDVHLCINNELSEYRRIAQRAdlelqs 209
Cdd:TIGR02168 673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEE----LEEELEQLRKELEELSRQISALRKDLARLEAEV------ 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 210 tRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFEIQSYsdwKEVVKTSRERLASVPdllaevEHL 289
Cdd:TIGR02168 743 -EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL---KEELKALREALDELR------AEL 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 290 RSHNKHLNTLIGDKLLLEEQVYDYKTRLEREEgARAEAASLQVKLLHMEQElkewvkvaqdhclantlvspmALRSRIEQ 369
Cdd:TIGR02168 813 TLLNEEAANLRERLESLERRIAATERRLEDLE-EQIEELSEDIESLAAEIE---------------------ELEELIEE 870
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 370 LLKEDIIHVAEKTSSASDTKHLNTTIRDLEHKcaiylknIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFdk 449
Cdd:TIGR02168 871 LESELEALLNERASLEEALALLRSELEELSEE-------LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL-- 941
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 450 dttLSNASVadmtqdmQVRVRMEVLERTVTGYKDMCATLEREIQSLRQQ--EL--VNEPAGEGYDSVKKELDTLRMENDR 525
Cdd:TIGR02168 942 ---QERLSE-------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKikELgpVNLAAIEEYEELKERYDFLTAQKED 1011
|
....*....
gi 24652071 526 LRRRKEELE 534
Cdd:TIGR02168 1012 LTEAKETLE 1020
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
72-590 |
1.25e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.70 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 72 ASLQNSKLRTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALKDQcditSKKNLELQDDLKALRKRELVLKNEAS 151
Cdd:COG1196 272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL----EEELAELEEELEELEEELEELEEELE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 152 RATAELNQLRLKFDESTLKLQKEKYLQKEDARdvhlcinnELSEYRRIAQRADLELQSTRNELERLRQLNEELQARASgf 231
Cdd:COG1196 348 EAEEELEEAEAELAEAEEALLEAEAELAEAEE--------ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE-- 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 232 EQLRANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSHNKHLNTLIGDKLLLEEQVY 311
Cdd:COG1196 418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 312 DYKTRLE-REEGARAEAASLQVKLLHME-QELKEWVKVAQDHCLANTLVSPMALRSRIEQLLKEDIIHVAEKTSSASDTK 389
Cdd:COG1196 498 EAEADYEgFLEGVKAALLLAGLRGLAGAvAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 390 HLNTTIRDLEHKCAIYLKNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYKQLVENFDKDTTLSNASVADMTQDMQVRV 469
Cdd:COG1196 578 PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGS 657
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 470 RMEVLERTVTGYKDMCATLEREIQSLRQQELVNEPAGEGYDSVKKELDTLRMENDRLRRRKEELEMEMMHRCLRGDFNMK 549
Cdd:COG1196 658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 24652071 550 DFKVVHFSENPAAEAYESTKNMM--EKLQAEIERLKRRNKKLE 590
Cdd:COG1196 738 LEELLEEEELLEEEALEELPEPPdlEELERELERLEREIEALG 780
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
136-443 |
4.01e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 136 LKALRKRELVLKNEASRATAELNQLRLKFDEstlklqkekylqkedardvhlcINNELSEYRRIAQR--ADLELQSTRNE 213
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDA----------------------LQERREALQRLAEYswDEIDVASAERE 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 214 LERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFEI----QSYSDWKEVVKTSRERLASVPDLLAEVEHL 289
Cdd:COG4913 670 IAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIgrleKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 290 RshnkhLNTLIGDkLLLEEQVYDYKTRLERE-EGARAEAASLQVKLL-HMEQELKEWVKVAQDHclantLVSPMALRSRI 367
Cdd:COG4913 750 L-----LEERFAA-ALGDAVERELRENLEERiDALRARLNRAEEELErAMRAFNREWPAETADL-----DADLESLPEYL 818
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 368 EQL--LKEDIIHVAE-------KTSSASDTKHLNTTIRDLEHkcAIYlKNIEDLNIGLKRHK-NFKERLQ-RKLITVSKE 436
Cdd:COG4913 819 ALLdrLEEDGLPEYEerfkellNENSIEFVADLLSKLRRAIR--EIK-ERIDPLNDSLKRIPfGPGRYLRlEARPRPDPE 895
|
....*...
gi 24652071 437 -RDFYKQL 443
Cdd:COG4913 896 vREFRQEL 903
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
198-344 |
1.07e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.45 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 198 RIAQRADLELQSTRNELERLRQLNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTsRERLA 277
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELA 142
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24652071 278 SVPDllaEVEHLRSHNKHLNTLIGDKLLLEEQVYDYKTRLERE------------EGARAEAASLQVKLLHMEQELKEW 344
Cdd:COG4717 143 ELPE---RLEELEERLEELRELEEELEELEAELAELQEELEELleqlslateeelQDLAEELEELQQRLAELEEELEEA 218
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
75-639 |
1.14e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.40 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 75 QNSKLRTELIETKAIVIQLRNEIEKKSREHKEAILLAENKSTALkdqcditskkNLELQDDLKALRKRELVLKNEASRAT 154
Cdd:pfam05483 170 KTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEM----------HFKLKEDHEKIQHLEEEYKKEINDKE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 155 AELNQLRLKFDESTLKLQKEKYLQKEDARDVhlcinNELSEyrriaqradlelqSTRNELERLRQLNEELQARASGFEQL 234
Cdd:pfam05483 240 KQVSLLLIQITEKENKMKDLTFLLEESRDKA-----NQLEE-------------KTKLQDENLKELIEKKDHLTKELEDI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 235 RANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASvpdllaevehlrSHNKHLNTLIGDKLLLEEQVYDYK 314
Cdd:pfam05483 302 KMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKA------------AHSFVVTEFEATTCSLEELLRTEQ 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 315 TRLEREEGaraeaaslQVKLLHME-----QELKEWVKVAQDHCLAntlvspmalRSRIEQLLKEDIIHVAEKTSSASDTK 389
Cdd:pfam05483 370 QRLEKNED--------QLKIITMElqkksSELEEMTKFKNNKEVE---------LEELKKILAEDEKLLDEKKQFEKIAE 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 390 HLNTTIRDLEHKCAIYLKNIEDLNIGLKRHKNFKERLQRKLITVSKERDFYK----QLVENFDKdTTLSNASVADMTQDM 465
Cdd:pfam05483 433 ELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKlkniELTAHCDK-LLLENKELTQEASDM 511
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 466 QVRVRMEvlERTVTGYKDMCATLEREIQSLRQQELvnepagegydSVKKELDTLRMEndrLRRRKEELEMEMmhrclrgD 545
Cdd:pfam05483 512 TLELKKH--QEDIINCKKQEERMLKQIENLEEKEM----------NLRDELESVREE---FIQKGDEVKCKL-------D 569
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 546 FNMKDFKVVHFSENPAAEAYESTKNMMEKLQAEIERLKRRNKKLEDDNEQrLNETTSTGGMTLNFKEF--NQLQAELESA 623
Cdd:pfam05483 570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKA-LKKKGSAENKQLNAYEIkvNKLELELASA 648
|
570
....*....|....*.
gi 24652071 624 NGKMRKMRDCFKAARE 639
Cdd:pfam05483 649 KQKFEEIIDNYQKEIE 664
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
75-292 |
1.16e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.19 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 75 QNSKLRTELIETKAIVIQLRNEIEKKSREHKEAILLAENKS---TALKDQCDITSKKNLELQDDLKALRKRELVLKNEAS 151
Cdd:pfam07888 74 QRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSeekDALLAQRAAHEARIRELEEDIKTLTQRVLERETELE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 152 RATAELNQL-RLKFDESTLKLQKEKYLQKEDARDVHLCinnelseyrriaqradLELQSTRNELERlrqlneelqaRASG 230
Cdd:pfam07888 154 RMKERAKKAgAQRKEEEAERKQLQAKLQQTEEELRSLS----------------KEFQELRNSLAQ----------RDTQ 207
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24652071 231 FEQLRANHEKQTQSLKVANDRIQELEFEIQSYSDWKEVVKTSRERLASVPDLLAEVEHLRSH 292
Cdd:pfam07888 208 VLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDR 269
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
201-343 |
2.01e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 201 QRADLELQSTRNELERLRQ----LNEELQARASGFEQLRANHEKQTQSLKVANDRIQELEFEIQsysDWKEVVKTSRERL 276
Cdd:COG1579 6 LRALLDLQELDSELDRLEHrlkeLPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIE---EVEARIKKYEEQL 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24652071 277 ASVPD------LLAEVEHLRSHNKHLNTLIgdkLLLEEQVYDYKTRLEREEGARAEaasLQVKLLHMEQELKE 343
Cdd:COG1579 83 GNVRNnkeyeaLQKEIESLKRRISDLEDEI---LELMERIEELEEELAELEAELAE---LEAELEEKKAELDE 149
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
107-386 |
5.85e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 39.75 E-value: 5.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 107 AILLAENKSTALKDQCDITSKKNLELQDDLKALRKRELVLKNEASRATAELNQLRLKFDESTLKLQKekylqkedardvh 186
Cdd:COG4942 7 LALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA------------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 187 lcINNELSEYRRiaqradlELQSTRNELERLRQLNEELQARASgfEQLRANHEKQTQSLKVANDRIQELEFEIQSYSDWK 266
Cdd:COG4942 74 --LEQELAALEA-------ELAELEKEIAELRAELEAQKEELA--ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24652071 267 EVVKTSRERLASVPDLLAEVEHLRshnKHLNTLIGDKLLLEEQVYDYKTRLEREEGARAEA-ASLQVKLLHMEQELKEWV 345
Cdd:COG4942 143 YLAPARREQAEELRADLAELAALR---AELEAERAELEALLAELEEERAALEALKAERQKLlARLEKELAELAAELAELQ 219
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 24652071 346 KVAQDhclantlvspmaLRSRIEQLLKEdIIHVAEKTSSAS 386
Cdd:COG4942 220 QEAEE------------LEALIARLEAE-AAAAAERTPAAG 247
|
|
| |
