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Conserved domains on  [gi|22026840|ref|NP_610375|]
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uncharacterized protein Dmel_CG2127, isoform A [Drosophila melanogaster]

Protein Classification

DUF1431 domain-containing protein( domain architecture ID 10537944)

DM6 domain-containing protein similar to Drosophila melanogaster hug-bell and swift-tuttle

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF1431 pfam07248
Protein of unknown function (DUF1431); This family contains a number of Drosophila ...
133-290 1.55e-54

Protein of unknown function (DUF1431); This family contains a number of Drosophila melanogaster proteins of unknown function. These contain several conserved cysteine residues.


:

Pssm-ID: 429365  Cd Length: 155  Bit Score: 174.45  E-value: 1.55e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22026840   133 CEYVPKCDVPVRYDIQHYRISDKEARQYQVTWNECPRLVIKPKKVCIHAKRPRPKPCRRQRKTVVATARPTMPMLNPmec 212
Cdd:pfam07248   1 CLEDPCAKELPRFDLIYYKPSDKLKRKYQRTWVECPPIRRKPKKVCCYDKIKPPEVKRRKRKKCPKTACTRKPMPCK--- 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22026840   213 KKAEDSSPCPRWTLPCCKPARIPPSCHRERRPTDCTKRPAPYPSFSECKREELTNAPPTECLCLRVPMACEMWAELRR 290
Cdd:pfam07248  78 DAKGKPEPCPRFTMPCCKPARIPPKCRRTRRPSDCVKRKTPYPSFSECRRPKLPPLPPVECECLKKPSMCEVWRYYRR 155
 
Name Accession Description Interval E-value
DUF1431 pfam07248
Protein of unknown function (DUF1431); This family contains a number of Drosophila ...
133-290 1.55e-54

Protein of unknown function (DUF1431); This family contains a number of Drosophila melanogaster proteins of unknown function. These contain several conserved cysteine residues.


Pssm-ID: 429365  Cd Length: 155  Bit Score: 174.45  E-value: 1.55e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22026840   133 CEYVPKCDVPVRYDIQHYRISDKEARQYQVTWNECPRLVIKPKKVCIHAKRPRPKPCRRQRKTVVATARPTMPMLNPmec 212
Cdd:pfam07248   1 CLEDPCAKELPRFDLIYYKPSDKLKRKYQRTWVECPPIRRKPKKVCCYDKIKPPEVKRRKRKKCPKTACTRKPMPCK--- 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22026840   213 KKAEDSSPCPRWTLPCCKPARIPPSCHRERRPTDCTKRPAPYPSFSECKREELTNAPPTECLCLRVPMACEMWAELRR 290
Cdd:pfam07248  78 DAKGKPEPCPRFTMPCCKPARIPPKCRRTRRPSDCVKRKTPYPSFSECRRPKLPPLPPVECECLKKPSMCEVWRYYRR 155
DM6 smart00689
Cysteine-rich domain currently specific to Drosophila;
137-289 1.56e-52

Cysteine-rich domain currently specific to Drosophila;


Pssm-ID: 214775  Cd Length: 157  Bit Score: 169.57  E-value: 1.56e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22026840    137 PKCDVPV-RYDIQHYRISDKEARQYQVTWNECPRLVIKPKKVCIHAKRPR-PKPCRRQRKTVVATARPTMPmlNPMECKK 214
Cdd:smart00689   5 DPCALPLpRFDLLYYKPSDKANRKYQRTWVECPPIMIKPKRICCPDKEPRiPRPRRRRRKPRCPSAACPTG--NPMPCKP 82
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22026840    215 AEDSSPCPRWTLPCCKPARIPPSCHRERRPTDCTKRPAPYPSFSECKREELTNAPPTECLCLRVPMACEMWAELR 289
Cdd:smart00689  83 EAGKSPCPRIRMPCCKPARRPPSCRAVRRPSDCVKRRTPYPSFSECKREKLPKPPPRECECLKKPSLCEVWREYR 157
 
Name Accession Description Interval E-value
DUF1431 pfam07248
Protein of unknown function (DUF1431); This family contains a number of Drosophila ...
133-290 1.55e-54

Protein of unknown function (DUF1431); This family contains a number of Drosophila melanogaster proteins of unknown function. These contain several conserved cysteine residues.


Pssm-ID: 429365  Cd Length: 155  Bit Score: 174.45  E-value: 1.55e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22026840   133 CEYVPKCDVPVRYDIQHYRISDKEARQYQVTWNECPRLVIKPKKVCIHAKRPRPKPCRRQRKTVVATARPTMPMLNPmec 212
Cdd:pfam07248   1 CLEDPCAKELPRFDLIYYKPSDKLKRKYQRTWVECPPIRRKPKKVCCYDKIKPPEVKRRKRKKCPKTACTRKPMPCK--- 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22026840   213 KKAEDSSPCPRWTLPCCKPARIPPSCHRERRPTDCTKRPAPYPSFSECKREELTNAPPTECLCLRVPMACEMWAELRR 290
Cdd:pfam07248  78 DAKGKPEPCPRFTMPCCKPARIPPKCRRTRRPSDCVKRKTPYPSFSECRRPKLPPLPPVECECLKKPSMCEVWRYYRR 155
DM6 smart00689
Cysteine-rich domain currently specific to Drosophila;
137-289 1.56e-52

Cysteine-rich domain currently specific to Drosophila;


Pssm-ID: 214775  Cd Length: 157  Bit Score: 169.57  E-value: 1.56e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22026840    137 PKCDVPV-RYDIQHYRISDKEARQYQVTWNECPRLVIKPKKVCIHAKRPR-PKPCRRQRKTVVATARPTMPmlNPMECKK 214
Cdd:smart00689   5 DPCALPLpRFDLLYYKPSDKANRKYQRTWVECPPIMIKPKRICCPDKEPRiPRPRRRRRKPRCPSAACPTG--NPMPCKP 82
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22026840    215 AEDSSPCPRWTLPCCKPARIPPSCHRERRPTDCTKRPAPYPSFSECKREELTNAPPTECLCLRVPMACEMWAELR 289
Cdd:smart00689  83 EAGKSPCPRIRMPCCKPARRPPSCRAVRRPSDCVKRRTPYPSFSECKREKLPKPPPRECECLKKPSLCEVWREYR 157
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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