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Conserved domains on  [gi|19921672|ref|NP_610185|]
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zinc transporter 41F, isoform A [Drosophila melanogaster]

Protein Classification

cation diffusion facilitator family transporter( domain architecture ID 11440813)

cation diffusion facilitator (CDF) family transporter facilitates the active efflux of one or more from a variety of metal cations including Zn, Cd, Ni, Co, Mn, and Cu

Gene Ontology:  GO:0008324|GO:0046872
TCDB:  2.A.4

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CzcD COG1230
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];
132-495 1.27e-77

Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440843 [Multi-domain]  Cd Length: 294  Bit Score: 245.03  E-value: 1.27e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIW 211
Cdd:COG1230  19 RLLIALALTLGFMVVEIVGGLLSGSLALLADAGHMLSDALALGLALFAYRLARRPADARFTFGYKRAEILAALANALLLL 98
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 212 FVTTLLVVVAIERIFSQDfELNADMMMLISGIGIVINIVMMFVLHGswfvngnghghshshshshshshgnghepndsls 291
Cdd:COG1230  99 VVAGYILYEAIQRLFNPP-PVAGGGMLVVAVIGLVVNLVSAWLLHR---------------------------------- 143
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 292 qtrsnsnflttigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelaHEDKNLNLRAAMIHVIGDLVQSIG 371
Cdd:COG1230 144 --------------------------------------------------------GSKHDLNLRGAYLHVLADALGSVA 167
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 372 VFLAAVLIKVCpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTS 451
Cdd:COG1230 168 VIVAALVILFT-GWTWLDPLLSLLIALLILRSAWGLLRESLRILLEGVPDGIDLEEVRAALEALPGVADVHDLHVWSLSS 246
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....
gi 19921672 452 QQRVLMVHLVTDSRADGNEVLQAATALVSSpRYNIKHSTIQLEP 495
Cdd:COG1230 247 GENALTAHVVVDDGADADAILDEIRELLAE-RFGIEHVTIQIET 289
 
Name Accession Description Interval E-value
CzcD COG1230
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];
132-495 1.27e-77

Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];


Pssm-ID: 440843 [Multi-domain]  Cd Length: 294  Bit Score: 245.03  E-value: 1.27e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIW 211
Cdd:COG1230  19 RLLIALALTLGFMVVEIVGGLLSGSLALLADAGHMLSDALALGLALFAYRLARRPADARFTFGYKRAEILAALANALLLL 98
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 212 FVTTLLVVVAIERIFSQDfELNADMMMLISGIGIVINIVMMFVLHGswfvngnghghshshshshshshgnghepndsls 291
Cdd:COG1230  99 VVAGYILYEAIQRLFNPP-PVAGGGMLVVAVIGLVVNLVSAWLLHR---------------------------------- 143
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 292 qtrsnsnflttigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelaHEDKNLNLRAAMIHVIGDLVQSIG 371
Cdd:COG1230 144 --------------------------------------------------------GSKHDLNLRGAYLHVLADALGSVA 167
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 372 VFLAAVLIKVCpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTS 451
Cdd:COG1230 168 VIVAALVILFT-GWTWLDPLLSLLIALLILRSAWGLLRESLRILLEGVPDGIDLEEVRAALEALPGVADVHDLHVWSLSS 246
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....
gi 19921672 452 QQRVLMVHLVTDSRADGNEVLQAATALVSSpRYNIKHSTIQLEP 495
Cdd:COG1230 247 GENALTAHVVVDDGADADAILDEIRELLAE-RFGIEHVTIQIET 289
CDF TIGR01297
cation diffusion facilitator family transporter; This model describes a broadly distributed ...
142-495 1.09e-66

cation diffusion facilitator family transporter; This model describes a broadly distributed family of transporters, a number of which have been shown to transport divalent cations of cobalt, cadmium and/or zinc. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273544 [Multi-domain]  Cd Length: 268  Bit Score: 215.55  E-value: 1.09e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   142 VFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVA 221
Cdd:TIGR01297   1 LLMLIKIVGGLLSGSLALLADAIHSLSDVAASAIALLALRISRRPADERHPFGHGRAEILAALLNGLFLVVVALFILYEA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   222 IERIFSQDFELNADMMMLISGIGIVINIVMMFVLHgswfvngnghghshshshshshshgnghepndslsqtrsnsnflt 301
Cdd:TIGR01297  81 IERLINPEPEIDGGTMLIVAIVGLIVNLILALYLH--------------------------------------------- 115
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   302 tigsqsastadeedsirkeinsnehkivitngkkptltgtsnmELAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKV 381
Cdd:TIGR01297 116 -------------------------------------------RVGHRLGSLALRAAALHVLSDALSSVGVLIGALLIYF 152
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   382 cpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLV 461
Cdd:TIGR01297 153 --GWHWADPIAALLISLLILYTAFRLLKESINVLLDAAPDEEDLEEIKKAILSIPGVKGVHDLHIWRIGPGKLFLDVHVV 230
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 19921672   462 TDSRADGNEVLQAATALVSS---PRYNIKHSTIQLEP 495
Cdd:TIGR01297 231 VDPDLDLKQAHDIALEIEREilkRHPGIEHVTIQVEP 267
Cation_efflux pfam01545
Cation efflux family; Members of this family are integral membrane proteins, that are found to ...
142-416 7.63e-35

Cation efflux family; Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.


Pssm-ID: 426316 [Multi-domain]  Cd Length: 189  Bit Score: 128.93  E-value: 7.63e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   142 VFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVA 221
Cdd:pfam01545   1 LLALVKLAAGLLTGSLALLADAVHSLIDLISSLLALLALRLSRKPPDERFPFGHGRLEPLAALVVGILLLGGGVFLLYES 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   222 IERIFSQDFELNADMMMLISGIGIVINIVMMFVLHGSwfvngnghghshshshshshshgnghepndslsqtrsnsnflt 301
Cdd:pfam01545  81 IQRLLSPGEEIDPGLALILALVSLLVNLFLLLYLRRA------------------------------------------- 117
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   302 tigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLI-- 379
Cdd:pfam01545 118 ---------------------------------------------ARRIRSPALKADALHALSDVLASLGVLISALLIyl 152
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 19921672   380 KVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIV 416
Cdd:pfam01545 153 GPITGGLLADPLASLLIGLLILYTALRLLKESLSILL 189
PRK03557 PRK03557
CDF family zinc transporter ZitB;
132-494 3.26e-34

CDF family zinc transporter ZitB;


Pssm-ID: 235130 [Multi-domain]  Cd Length: 312  Bit Score: 131.02  E-value: 3.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIW 211
Cdd:PRK03557  20 RLLYAFGVTAGFMLVEVIGGFLSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  212 FVTTLLVVVAIERiFSQDFELNADMMMLISGIGIVINIVMMFVLH-GSwfvngnghghshshshshshshgnghepndsl 290
Cdd:PRK03557 100 VITILIVWEAIER-FRTPRPVAGGMMMAIAVAGLLANILSFWLLHhGS-------------------------------- 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  291 sqtrsnsnflttigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelahEDKNLNLRAAMIHVIGDLVQSI 370
Cdd:PRK03557 147 ----------------------------------------------------------EEKNLNVRAAALHVLGDLLGSV 168
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  371 GVFLAAVLIkVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELG-SIEGVRSLHHLNVWqQ 449
Cdd:PRK03557 169 GAIIAALII-IWTGWTPADPILSILVSVLVLRSAWRLLKESVNELLEGAPVSLDIAELKRRLCrEIPEVRNVHHVHVW-M 246
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 19921672  450 TSQQRVLMVHLVTDSRADGNEVLQAATALVSSpRYNIKHSTIQLE 494
Cdd:PRK03557 247 VGEKPVMTLHVQVIPPHDHDALLDRIQDYLMH-HYQIEHATIQME 290
 
Name Accession Description Interval E-value
CzcD COG1230
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];
132-495 1.27e-77

Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism];


Pssm-ID: 440843 [Multi-domain]  Cd Length: 294  Bit Score: 245.03  E-value: 1.27e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIW 211
Cdd:COG1230  19 RLLIALALTLGFMVVEIVGGLLSGSLALLADAGHMLSDALALGLALFAYRLARRPADARFTFGYKRAEILAALANALLLL 98
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 212 FVTTLLVVVAIERIFSQDfELNADMMMLISGIGIVINIVMMFVLHGswfvngnghghshshshshshshgnghepndsls 291
Cdd:COG1230  99 VVAGYILYEAIQRLFNPP-PVAGGGMLVVAVIGLVVNLVSAWLLHR---------------------------------- 143
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 292 qtrsnsnflttigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelaHEDKNLNLRAAMIHVIGDLVQSIG 371
Cdd:COG1230 144 --------------------------------------------------------GSKHDLNLRGAYLHVLADALGSVA 167
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 372 VFLAAVLIKVCpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTS 451
Cdd:COG1230 168 VIVAALVILFT-GWTWLDPLLSLLIALLILRSAWGLLRESLRILLEGVPDGIDLEEVRAALEALPGVADVHDLHVWSLSS 246
                       330       340       350       360
                ....*....|....*....|....*....|....*....|....
gi 19921672 452 QQRVLMVHLVTDSRADGNEVLQAATALVSSpRYNIKHSTIQLEP 495
Cdd:COG1230 247 GENALTAHVVVDDGADADAILDEIRELLAE-RFGIEHVTIQIET 289
CDF TIGR01297
cation diffusion facilitator family transporter; This model describes a broadly distributed ...
142-495 1.09e-66

cation diffusion facilitator family transporter; This model describes a broadly distributed family of transporters, a number of which have been shown to transport divalent cations of cobalt, cadmium and/or zinc. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273544 [Multi-domain]  Cd Length: 268  Bit Score: 215.55  E-value: 1.09e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   142 VFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVA 221
Cdd:TIGR01297   1 LLMLIKIVGGLLSGSLALLADAIHSLSDVAASAIALLALRISRRPADERHPFGHGRAEILAALLNGLFLVVVALFILYEA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   222 IERIFSQDFELNADMMMLISGIGIVINIVMMFVLHgswfvngnghghshshshshshshgnghepndslsqtrsnsnflt 301
Cdd:TIGR01297  81 IERLINPEPEIDGGTMLIVAIVGLIVNLILALYLH--------------------------------------------- 115
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   302 tigsqsastadeedsirkeinsnehkivitngkkptltgtsnmELAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKV 381
Cdd:TIGR01297 116 -------------------------------------------RVGHRLGSLALRAAALHVLSDALSSVGVLIGALLIYF 152
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   382 cpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLV 461
Cdd:TIGR01297 153 --GWHWADPIAALLISLLILYTAFRLLKESINVLLDAAPDEEDLEEIKKAILSIPGVKGVHDLHIWRIGPGKLFLDVHVV 230
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 19921672   462 TDSRADGNEVLQAATALVSS---PRYNIKHSTIQLEP 495
Cdd:TIGR01297 231 VDPDLDLKQAHDIALEIEREilkRHPGIEHVTIQVEP 267
Cation_efflux pfam01545
Cation efflux family; Members of this family are integral membrane proteins, that are found to ...
142-416 7.63e-35

Cation efflux family; Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.


Pssm-ID: 426316 [Multi-domain]  Cd Length: 189  Bit Score: 128.93  E-value: 7.63e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   142 VFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVA 221
Cdd:pfam01545   1 LLALVKLAAGLLTGSLALLADAVHSLIDLISSLLALLALRLSRKPPDERFPFGHGRLEPLAALVVGILLLGGGVFLLYES 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   222 IERIFSQDFELNADMMMLISGIGIVINIVMMFVLHGSwfvngnghghshshshshshshgnghepndslsqtrsnsnflt 301
Cdd:pfam01545  81 IQRLLSPGEEIDPGLALILALVSLLVNLFLLLYLRRA------------------------------------------- 117
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672   302 tigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLI-- 379
Cdd:pfam01545 118 ---------------------------------------------ARRIRSPALKADALHALSDVLASLGVLISALLIyl 152
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 19921672   380 KVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIV 416
Cdd:pfam01545 153 GPITGGLLADPLASLLIGLLILYTALRLLKESLSILL 189
PRK03557 PRK03557
CDF family zinc transporter ZitB;
132-494 3.26e-34

CDF family zinc transporter ZitB;


Pssm-ID: 235130 [Multi-domain]  Cd Length: 312  Bit Score: 131.02  E-value: 3.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  132 KIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIW 211
Cdd:PRK03557  20 RLLYAFGVTAGFMLVEVIGGFLSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  212 FVTTLLVVVAIERiFSQDFELNADMMMLISGIGIVINIVMMFVLH-GSwfvngnghghshshshshshshgnghepndsl 290
Cdd:PRK03557 100 VITILIVWEAIER-FRTPRPVAGGMMMAIAVAGLLANILSFWLLHhGS-------------------------------- 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  291 sqtrsnsnflttigsqsastadeedsirkeinsnehkivitngkkptltgtsnmelahEDKNLNLRAAMIHVIGDLVQSI 370
Cdd:PRK03557 147 ----------------------------------------------------------EEKNLNVRAAALHVLGDLLGSV 168
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  371 GVFLAAVLIkVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELG-SIEGVRSLHHLNVWqQ 449
Cdd:PRK03557 169 GAIIAALII-IWTGWTPADPILSILVSVLVLRSAWRLLKESVNELLEGAPVSLDIAELKRRLCrEIPEVRNVHHVHVW-M 246
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 19921672  450 TSQQRVLMVHLVTDSRADGNEVLQAATALVSSpRYNIKHSTIQLE 494
Cdd:PRK03557 247 VGEKPVMTLHVQVIPPHDHDALLDRIQDYLMH-HYQIEHATIQME 290
FieF COG0053
Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];
133-495 1.62e-22

Divalent metal cation (Fe/Co/Zn/Cd) efflux pump [Inorganic ion transport and metabolism];


Pssm-ID: 439823 [Multi-domain]  Cd Length: 284  Bit Score: 97.10  E-value: 1.62e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 133 IMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWF 212
Cdd:COG0053   5 ALASLAANLLLAVLKLVAGLLTGSVALLADALHSLSDLVASLLVLLGLRLAAKPADEEHPYGHGKAEYLASLIVAVLILL 84
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 213 VTTLLVVVAIERIFSQDFELNADMMMLISGIGIVINIVMMFVLhgswfvngnghghshshshshshshgnghepndslsq 292
Cdd:COG0053  85 AGLFILYEAIERLLHPEPVEPSGLGLAVLLISIVVNEALARYL------------------------------------- 127
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 293 trsnsnflttigsqsastadeedsIR--KEINSNEhkivitngkkptltgtsnmelahedknlnLRAAMIHVIGDLVQSI 370
Cdd:COG0053 128 ------------------------RRvgKKTGSPA-----------------------------LKADALHDRSDALTSL 154
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672 371 GVFLAAVLIKVCpGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVN-AVPQNLNMRTLHLeLGSIEGVRSLHHLNVwQQ 449
Cdd:COG0053 155 GVLIGLLLALLT-GWPWLDPIAAILIGLLILKVAYKLARESLSLLMDeALDEELVERIRAI-ILSVPGVIGVHDLRT-RK 231
                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|.
gi 19921672 450 TSQQRVLMVHLVTDSRADGNEVLQAATALVSS-----PryNIKHSTIQLEP 495
Cdd:COG0053 232 SGPRIFVDLHIEVDPDLTVEEAHDIADRIEAAlreefP--GVADVTIHVEP 280
fieF PRK09509
CDF family cation-efflux pump FieF;
135-254 8.88e-03

CDF family cation-efflux pump FieF;


Pssm-ID: 181919 [Multi-domain]  Cd Length: 299  Bit Score: 38.12  E-value: 8.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19921672  135 LAVALCCVFMIIEFLGGYVAGSLAIMtdAAHLAS--DCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWF 212
Cdd:PRK09509  15 AATAMASLLLLIKIFAWWYTGSVSLL--AALVDSlvDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISG 92
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 19921672  213 VTTLLVVVAIERIFSQDfELNAdmmmliSGIGIVINIVMMFV 254
Cdd:PRK09509  93 SALFLFLTGIQHLISPT-PMND------PGVGIIVTLVALIC 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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