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Conserved domains on  [gi|281364932|ref|NP_609581|]
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intraflagellar transport 43 [Drosophila melanogaster]

Protein Classification

intraflagellar transport protein 43( domain architecture ID 10633880)

intraflagellar transport protein 43 (IFT43) is a component of the IFT complex A (IFT-A), which is required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), and is involved in ciliogenesis

Gene Symbol:  IFT43
Gene Ontology:  GO:0030991
PubMed:  28207750

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IFT43 pfam15305
Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit ...
 85-210 8.38e-25

Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit of the IFT complex A (IFT-A) machinery of primary cilia.


:

Pssm-ID: 464631  Cd Length: 136  Bit Score: 94.76  E-value: 8.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281364932   85 WADSGLKGLKSKK-------NSFDDERFKQTKSATNSIPTDDIPVIPDMDDVKDEIMLNEIVEPPTIGTSRSAVLKEANS 157
Cdd:pfam15305   1 WADESSKKRGGQKrgrreasAEGEDERLRKQTPYESDDEDEDIPVIPDLEEVQEEDLTTQVAAAPSIQVNRVQTYRELDN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281364932  158 DLLSQYAFSAVD-GFDLSILTDCLVPQESLNEKDDLWQWDKLFTEVTAEIHSDK 210
Cdd:pfam15305  81 DLKKTAALQTLDgGIDLSLLTKVLSPEEEVREDDVPWDWDHLFTEVSSELQAEW 134
 
Name Accession Description Interval E-value
IFT43 pfam15305
Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit ...
 85-210 8.38e-25

Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit of the IFT complex A (IFT-A) machinery of primary cilia.


Pssm-ID: 464631  Cd Length: 136  Bit Score: 94.76  E-value: 8.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281364932   85 WADSGLKGLKSKK-------NSFDDERFKQTKSATNSIPTDDIPVIPDMDDVKDEIMLNEIVEPPTIGTSRSAVLKEANS 157
Cdd:pfam15305   1 WADESSKKRGGQKrgrreasAEGEDERLRKQTPYESDDEDEDIPVIPDLEEVQEEDLTTQVAAAPSIQVNRVQTYRELDN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281364932  158 DLLSQYAFSAVD-GFDLSILTDCLVPQESLNEKDDLWQWDKLFTEVTAEIHSDK 210
Cdd:pfam15305  81 DLKKTAALQTLDgGIDLSLLTKVLSPEEEVREDDVPWDWDHLFTEVSSELQAEW 134
 
Name Accession Description Interval E-value
IFT43 pfam15305
Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit ...
 85-210 8.38e-25

Intraflagellar transport protein 43; Intraflagellar transport protein 43 (IFT43) is a subunit of the IFT complex A (IFT-A) machinery of primary cilia.


Pssm-ID: 464631  Cd Length: 136  Bit Score: 94.76  E-value: 8.38e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281364932   85 WADSGLKGLKSKK-------NSFDDERFKQTKSATNSIPTDDIPVIPDMDDVKDEIMLNEIVEPPTIGTSRSAVLKEANS 157
Cdd:pfam15305   1 WADESSKKRGGQKrgrreasAEGEDERLRKQTPYESDDEDEDIPVIPDLEEVQEEDLTTQVAAAPSIQVNRVQTYRELDN 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281364932  158 DLLSQYAFSAVD-GFDLSILTDCLVPQESLNEKDDLWQWDKLFTEVTAEIHSDK 210
Cdd:pfam15305  81 DLKKTAALQTLDgGIDLSLLTKVLSPEEEVREDDVPWDWDHLFTEVSSELQAEW 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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