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Conserved domains on  [gi|161076750|ref|NP_609083|]
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uncharacterized protein Dmel_CG18304, isoform A [Drosophila melanogaster]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 825-1538 1.53e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   825 AEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKtGEVDQKmKESLAQAQRE 904
Cdd:TIGR02168  177 TERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELR-EELEEL-QEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   905 RDELTARLKRMQLEaedklpprtakrvndltpkshlkkwVEELEDEISEMRvMLSSSGTDQLKALQSAKGALEEDLRKCK 984
Cdd:TIGR02168  255 LEELTAELQELEEK-------------------------LEELRLEVSELE-EEIEELQKELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   985 QKL-----SLAEGDVQRLKLLngssSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKRE 1059
Cdd:TIGR02168  309 ERLanlerQLEELEAQLEELE----SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1060 KEKLSSLEKDMEKQAKEKEKLEAKISQLDAEllsakksaekskssLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLS 1139
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDR--------------RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1140 AEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKIAEMDTIRIE---RTDMARKLSEAQKRIADLQA--- 1213
Cdd:TIGR02168  451 ELQEELERLEEALEELREE----LEEAEQALDAAERELAQLQARLDSLERLQENlegFSEGVKALLKNQSGLSGILGvls 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1214 ----------KALKTVNGNGAEY-----ERTVLKNKLAEKEHEYERL----------------RRENEMNIDLVFQLRKD 1262
Cdd:TIGR02168  527 elisvdegyeAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVtflpldsikgteiqgnDREILKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1263 N---------------------DDLNGKLSDYNRIEQAQS--SLNGHGAR------------------REAEIRELKEQ- 1300
Cdd:TIGR02168  607 LvkfdpklrkalsyllggvlvvDDLDNALELAKKLRPGYRivTLDGDLVRpggvitggsaktnssileRRREIEELEEKi 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1301 --LQSTELQMKSEVATVR---LRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTG-------- 1367
Cdd:TIGR02168  687 eeLEEKIAELEKALAELRkelEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEleaeieel 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1368 RQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVigsgstkl 1447
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER-------- 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1448 pgMKTKLELSWQKEREDQQRLLQETSTLARDLRQ-----TLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKkiaEL 1522
Cdd:TIGR02168  839 --RLEDLEEQIEELSEDIESLAAEIEELEELIEEleselEALLNERASLEEALALLRSELEELSEELRELESKRS---EL 913

                          810
                   ....*....|....*.
gi 161076750  1523 QCDLLELRDVHAKLRT 1538
Cdd:TIGR02168  914 RRELEELREKLAQLEL 929
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 348-1087 7.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAErEKSDILLRRLASMDTASNRtaasealnLQQKLNEMKEQLDRVTEDKRKLNLRMKELE 427
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELE-EKLEELRLEVSELEEEIEE--------LQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   428 NkgSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDtfrddEVKAKTSLQKDLEKATKNCRILSfkLKKSD 507
Cdd:TIGR02168  316 R--QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA-----ELEELEAELEELESRLEELEEQL--ETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   508 RKIETLEQERQssfnaeLSNKIKKLEEELRFSNELTRKLQAEAEELRNpgkkkapmlgvlgKSTSADAKFTRESLtrGGS 587
Cdd:TIGR02168  387 KVAQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLK-------------KLEEAELKELQAEL--EEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   588 QEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERkRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMST---- 663
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   664 ---------------------SVENLVTSNVAVTQTDFEVpDRNVSIERETMS--SPFAGLFPPSSSSRVGQSGSLLFPS 720
Cdd:TIGR02168  525 lselisvdegyeaaieaalggRLQAVVVENLNAAKKAIAF-LKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   721 AISHV------------LLSG---------AGRKLSPTPHPHRLapeVHAD-----RDEGISDEDDPAELRIL-----LE 769
Cdd:TIGR02168  604 AKDLVkfdpklrkalsyLLGGvlvvddldnALELAKKLRPGYRI---VTLDgdlvrPGGVITGGSAKTNSSILerrreIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   770 LNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQdssngskssllsLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQT 849
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQ------------LRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   850 VDSLKNQLSKLDTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKlpprTA 928
Cdd:TIGR02168  749 IAQLSKELTELEAEIEElEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL----RE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   929 KRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSgTDQLKALQSAKGALEEDL-RKCKQKLSLAEGDVQRLKLLNGSSSKV 1007
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1008 SELEQKLKRGDEEAKKLNSKLKDLEdkVKKQEAQLKLGETSKSTWESQSKRE---KEKLSSLEKDMEKQAKEKEKLEAKI 1084
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLE--LRLEGLEVRIDNLQERLSEEYSLTLeeaEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 161076750  1085 SQL 1087
Cdd:TIGR02168  982 KEL 984
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1651-1895 2.98e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.48  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1651 DEQERSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLS-------RNSSNNGS--LIRKSLSLDHSIQRDQNIW 1721
Cdd:PHA03307  133 DLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLsspeetaRAPSSPPAepPPSTPPAAASPRPPRRSSP 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1722 RQDDGSVSSMQSIDSELGGLVRDSSLDSRLDSRLSGGSTQSDIPRG-------PRKKKKGIMGKLRSLTKSSRNSESeiS 1794
Cdd:PHA03307  213 ISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPrpapitlPTRIWEASGWNGPSSRPGPASSSS--S 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1795 IQGSDSDISVASDmRSSKKDLRGRLSGMFKRSGSASRSESMER-AGSDQRPVAVTVVGHPDGPQPREPPPANslTPRPIR 1873
Cdd:PHA03307  291 PRERSPSPSPSSP-GSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSRPPPPAD--PSSPRK 367

                         250       260
                  ....*....|....*....|....*
gi 161076750 1874 SIPKPPSAGAPTTPT---TRRRVAK 1895
Cdd:PHA03307  368 RPRPSRAPSSPAASAgrpTRRRARA 392
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 825-1538 1.53e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   825 AEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKtGEVDQKmKESLAQAQRE 904
Cdd:TIGR02168  177 TERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELR-EELEEL-QEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   905 RDELTARLKRMQLEaedklpprtakrvndltpkshlkkwVEELEDEISEMRvMLSSSGTDQLKALQSAKGALEEDLRKCK 984
Cdd:TIGR02168  255 LEELTAELQELEEK-------------------------LEELRLEVSELE-EEIEELQKELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   985 QKL-----SLAEGDVQRLKLLngssSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKRE 1059
Cdd:TIGR02168  309 ERLanlerQLEELEAQLEELE----SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1060 KEKLSSLEKDMEKQAKEKEKLEAKISQLDAEllsakksaekskssLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLS 1139
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDR--------------RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1140 AEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKIAEMDTIRIE---RTDMARKLSEAQKRIADLQA--- 1213
Cdd:TIGR02168  451 ELQEELERLEEALEELREE----LEEAEQALDAAERELAQLQARLDSLERLQENlegFSEGVKALLKNQSGLSGILGvls 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1214 ----------KALKTVNGNGAEY-----ERTVLKNKLAEKEHEYERL----------------RRENEMNIDLVFQLRKD 1262
Cdd:TIGR02168  527 elisvdegyeAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVtflpldsikgteiqgnDREILKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1263 N---------------------DDLNGKLSDYNRIEQAQS--SLNGHGAR------------------REAEIRELKEQ- 1300
Cdd:TIGR02168  607 LvkfdpklrkalsyllggvlvvDDLDNALELAKKLRPGYRivTLDGDLVRpggvitggsaktnssileRRREIEELEEKi 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1301 --LQSTELQMKSEVATVR---LRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTG-------- 1367
Cdd:TIGR02168  687 eeLEEKIAELEKALAELRkelEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEleaeieel 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1368 RQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVigsgstkl 1447
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER-------- 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1448 pgMKTKLELSWQKEREDQQRLLQETSTLARDLRQ-----TLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKkiaEL 1522
Cdd:TIGR02168  839 --RLEDLEEQIEELSEDIESLAAEIEELEELIEEleselEALLNERASLEEALALLRSELEELSEELRELESKRS---EL 913

                          810
                   ....*....|....*.
gi 161076750  1523 QCDLLELRDVHAKLRT 1538
Cdd:TIGR02168  914 RRELEELREKLAQLEL 929
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
768-1266 1.81e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 79.34  E-value: 1.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  768 LELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAE----KKVKTLNEELVQLRRTL 843
Cdd:PRK03918  226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkelKEKAEEYIKLSEFYEEY 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  844 TEKEQTVDSLKNQLS-KLDTLETENDKLAKENKRLLALRKASEKTgevdQKMKESLAQAQRERDELTARLKRMQLEAEDK 922
Cdd:PRK03918  306 LDELREIEKRLSRLEeEINGIEERIKELEEKEERLEELKKKLKEL----EKRLEELEERHELYEEAKAKKEELERLKKRL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  923 LPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGAlEEDLRKCKQKLSlaegDVQRLKLLNG 1002
Cdd:PRK03918  382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELT----EEHRKELLEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1003 SSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETS---KSTWESQSKREKEKLSSLEKDMEKQAKEKEK 1079
Cdd:PRK03918  457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqlKELEEKLKKYNLEELEKKAEEYEKLKEKLIK 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1080 LEAKISQLDAElLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNnhweklseet 1159
Cdd:PRK03918  537 LKGEIKSLKKE-LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYL---------- 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1160 ilmraQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKAlktvngNGAEYERtvLKNKLAEKE 1239
Cdd:PRK03918  606 -----ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY------SEEEYEE--LREEYLELS 672

                         490       500
                  ....*....|....*....|....*..
gi 161076750 1240 HEYERLRRENEMNIDLVFQLRKDNDDL 1266
Cdd:PRK03918  673 RELAGLRAELEELEKRREEIKKTLEKL 699
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 945-1561 4.23e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 4.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  945 EELEDEISEMRvmlsssgtDQLKAL--QSAK----GALEEDLRKCKQKLSLAEGDVQRLKL------LNGSSSKVSELEQ 1012
Cdd:COG1196   189 ERLEDILGELE--------RQLEPLerQAEKaeryRELKEELKELEAELLLLKLRELEAELeeleaeLEELEAELEELEA 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1013 KLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELl 1092
Cdd:COG1196   261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL- 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1093 sakksaekskSSLEKEIKDLKTKASKSDsKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQS 1172
Cdd:COG1196   340 ----------EELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1173 LQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKtvngngAEYERTVLKNKLAEKEHEYERLRRenemn 1252
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------LEEEEEALLELLAELLEEAALLEA----- 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1253 idlvfQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELqmkSEVATVRLRYEQQVKNLSGELtS 1332
Cdd:COG1196   478 -----ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV---AVLIGVEAAYEAALEAALAAA-L 548

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1333 MQRQCERfkkdrdafkqmLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHL---------EDQLVESR 1403
Cdd:COG1196   549 QNIVVED-----------DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAvdlvasdlrEADARYYV 617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1404 LESSKIKTELVSERSANEIKIS-EMQSKLNEFEEERVIGSGSTKLPGMKTKLELswQKEREDQQRLLQETSTLARDLRQT 1482
Cdd:COG1196   618 LGDTLLGRTLVAARLEAALRRAvTLAGRLREVTLEGEGGSAGGSLTGGSRRELL--AALLEAEAELEELAERLAEEELEL 695

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1483 LFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCDLLELRDVHAKLRTSNEKLRRERErye----keLIKRR 1558
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDleelereleRLERE 775


                  ...
gi 161076750 1559 MEA 1561
Cdd:COG1196   776 IEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 348-1087 7.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAErEKSDILLRRLASMDTASNRtaasealnLQQKLNEMKEQLDRVTEDKRKLNLRMKELE 427
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELE-EKLEELRLEVSELEEEIEE--------LQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   428 NkgSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDtfrddEVKAKTSLQKDLEKATKNCRILSfkLKKSD 507
Cdd:TIGR02168  316 R--QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA-----ELEELEAELEELESRLEELEEQL--ETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   508 RKIETLEQERQssfnaeLSNKIKKLEEELRFSNELTRKLQAEAEELRNpgkkkapmlgvlgKSTSADAKFTRESLtrGGS 587
Cdd:TIGR02168  387 KVAQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLK-------------KLEEAELKELQAEL--EEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   588 QEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERkRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMST---- 663
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   664 ---------------------SVENLVTSNVAVTQTDFEVpDRNVSIERETMS--SPFAGLFPPSSSSRVGQSGSLLFPS 720
Cdd:TIGR02168  525 lselisvdegyeaaieaalggRLQAVVVENLNAAKKAIAF-LKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   721 AISHV------------LLSG---------AGRKLSPTPHPHRLapeVHAD-----RDEGISDEDDPAELRIL-----LE 769
Cdd:TIGR02168  604 AKDLVkfdpklrkalsyLLGGvlvvddldnALELAKKLRPGYRI---VTLDgdlvrPGGVITGGSAKTNSSILerrreIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   770 LNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQdssngskssllsLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQT 849
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQ------------LRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   850 VDSLKNQLSKLDTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKlpprTA 928
Cdd:TIGR02168  749 IAQLSKELTELEAEIEElEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL----RE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   929 KRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSgTDQLKALQSAKGALEEDL-RKCKQKLSLAEGDVQRLKLLNGSSSKV 1007
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1008 SELEQKLKRGDEEAKKLNSKLKDLEdkVKKQEAQLKLGETSKSTWESQSKRE---KEKLSSLEKDMEKQAKEKEKLEAKI 1084
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLE--LRLEGLEVRIDNLQERLSEEYSLTLeeaEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 161076750  1085 SQL 1087
Cdd:TIGR02168  982 KEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 350-915 2.90e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 2.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  350 QMKALKLELETMKTRAEKAEREKSDIllrrlasmdTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENK 429
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEEL---------EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  430 gsESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSfKLKKSDRK 509
Cdd:COG1196   304 --IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA-ELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  510 IETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRnpgkKKAPMLGVLGKSTSADAKFTRESLTRGGSQE 589
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE----LEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  590 DPQHLQRELQDSIERETDLKDQLkfAEEELQRLRDRERKRVRFSCGTQTEVPLEVVAF-------PRGTQTVATVQSDMS 662
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAAL--AELLEELAEAAARLLLLLEAEADYEGFLEGVKAalllaglRGLAGAVAVLIGVEA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  663 TSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAG--LFPPSSSSRVGQSGSLLFPSAISHVLLSGAGRKLSPTPHP 740
Cdd:COG1196   535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  741 HRLAPEVHADRDegiSDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGT 820
Cdd:COG1196   615 YYVLGDTLLGRT---LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  821 SSSAAEKKVKTLNEELVQLRRTLTEKEQtvdslknQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQ 900
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEE-------ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                         570
                  ....*....|....*
gi 161076750  901 AQRERDELTARLKRM 915
Cdd:COG1196   765 LERELERLEREIEAL 779
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 397-1278 7.31e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 7.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   397 NLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELRRK-------LQAAEQICEE---LMEENQSAKKEILNLQAE 466
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKkaleyyqLKEKLELEEEyllYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   467 MDEVQDTF---RDDEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSFNAEL-----SNKIKKLEEELRF 538
Cdd:pfam02463  246 LRDEQEEIessKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERrkvddEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   539 SNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDL----KDQLKF 614
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEelelKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   615 AEEELQRLRDRERKRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSNVAVTQTDF----EVPDRNVSIE 690
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEdllkETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   691 RETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVllsgaGRKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLEL 770
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGV-----GGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   771 NEQEASILRLKVEDLEKENAESKKyvRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTV 850
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLI--PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   851 DSLKNQLSKLDTLETENDKLAKENKRllalrkaSEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKR 930
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEV-------KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   931 VNDLTpkshlkkwvEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSEL 1010
Cdd:pfam02463  712 LKKLK---------LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1011 EQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE 1090
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1091 LLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKryEDLNNHWEKLSEETILMRAQLTTEK 1170
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK--ENEIEERIKEEAEILLKYEEEPEEL 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1171 QSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQ-AKALKTVNGNGAEYERTVLKNK---LAEKEHEYERLR 1246
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEfEEKEERYNKDELEKERLEEEKKkliRAIIEETCQRLK 1020

                          890       900       910
                   ....*....|....*....|....*....|..
gi 161076750  1247 RENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQ 1278
Cdd:pfam02463 1021 EFLELFVSINKGWNKVFFYLELGGSAELRLED 1052
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 348-1150 1.77e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAEREKSDILLRRLASM----DTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRM 423
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDeqeeIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   424 KELENKGSE--------SELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTF-RDDEVKAKTSLQKDLEKATK 494
Cdd:pfam02463  293 KEEEELKSEllklerrkVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKReAEEEEEEELEKLQEKLEQLE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   495 NCRILSFKLKKSDRKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGV---LGKST 571
Cdd:pfam02463  373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGkltEEKEE 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   572 SADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKRVRFSCGTQTEVPLEVVAFPRGT 651
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   652 qTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPfAGLFPPSSSSRVGQSGSLLFPSAISHVLLSGAG 731
Cdd:pfam02463  533 -DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA-RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   732 RKLSPTPHPHR-----LAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLE--KENAESKKYVRELQAKLR 804
Cdd:pfam02463  611 ATLEADEDDKRakvveGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEltKELLEIQELQEKAESELA 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   805 QDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENdkLAKENKRLLALRKAS 884
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEE--KSRLKKEEKEEEKSE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   885 EKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTD 964
Cdd:pfam02463  769 LSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   965 QLKALQSAKGALEEDL-RKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDlEDKVKKQEAQLK 1043
Cdd:pfam02463  849 EKLAEEELERLEEEITkEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK-ENEIEERIKEEA 927

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1044 LGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE--LLSAKKSAEKSKSSLEKEIKDLKTKASKSDS 1121
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKvnLMAIEEFEEKEERYNKDELEKERLEEEKKKL 1007

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 161076750  1122 KQVQD-------------------LKKQVEEVQASLSAEQKRYEDLNN 1150
Cdd:pfam02463 1008 IRAIIeetcqrlkeflelfvsinkGWNKVFFYLELGGSAELRLEDPDD 1055
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1651-1895 2.98e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.48  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1651 DEQERSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLS-------RNSSNNGS--LIRKSLSLDHSIQRDQNIW 1721
Cdd:PHA03307  133 DLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLsspeetaRAPSSPPAepPPSTPPAAASPRPPRRSSP 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1722 RQDDGSVSSMQSIDSELGGLVRDSSLDSRLDSRLSGGSTQSDIPRG-------PRKKKKGIMGKLRSLTKSSRNSESeiS 1794
Cdd:PHA03307  213 ISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPrpapitlPTRIWEASGWNGPSSRPGPASSSS--S 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1795 IQGSDSDISVASDmRSSKKDLRGRLSGMFKRSGSASRSESMER-AGSDQRPVAVTVVGHPDGPQPREPPPANslTPRPIR 1873
Cdd:PHA03307  291 PRERSPSPSPSSP-GSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSRPPPPAD--PSSPRK 367

                         250       260
                  ....*....|....*....|....*
gi 161076750 1874 SIPKPPSAGAPTTPT---TRRRVAK 1895
Cdd:PHA03307  368 RPRPSRAPSSPAASAgrpTRRRARA 392
PTZ00121 PTZ00121
MAEBL; Provisional
 182-629 1.78e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  182 AERVRKMNLLKKQRSLNSRENSRERSVPRREEESESTATPTPVVPDRPERSKSGTSLNQLAQAEQKraALPPKKVAVAST 261
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK--AEEAKKADEAKK 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  262 TTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVRRKEADSVASKEIKRQTvPAASISHSNSTSSTASTASKS 341
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA-DAAKKKAEEKKKADEAKKKAE 1401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  342 QDTNGMQEQMKAL--KLELETMKTRAEkaEREKSDILLRRLASmdtasnrtaASEALNLQQKLNEMK--EQLDRVTEDKR 417
Cdd:PTZ00121 1402 EDKKKADELKKAAaaKKKADEAKKKAE--EKKKADEAKKKAEE---------AKKADEAKKKAEEAKkaEEAKKKAEEAK 1470

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  418 KLNLRMKELENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKncr 497
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK--- 1547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  498 ilSFKLKKSD--RKIETLEQERQSSFNAELSNKIKKLEEELRFSNEltRKLQAEAEELRNPGKKKAPMLgvlgkSTSADA 575
Cdd:PTZ00121 1548 --ADELKKAEelKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE--ARIEEVMKLYEEEKKMKAEEA-----KKAEEA 1618

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 161076750  576 KFTRESLTRggsQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKR 629
Cdd:PTZ00121 1619 KIKAEELKK---AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK 1669
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 763-1142 3.48e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.39  E-value: 3.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  763 ELRILLELNEQE-----ASILRLKVEDLEKENAESKKYVRELQAKLRQdssngskssllslgtsssaAEKKVKTLNEELV 837
Cdd:NF033838  103 ELNVLKEKSEAEltsktKKELDAAFEQFKKDTLEPGKKVAEATKKVEE-------------------AEKKAKDQKEEDR 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  838 QLRRTLTEKeqtvdslknqlskldTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTaRLKRMQ 916
Cdd:NF033838  164 RNYPTNTYK---------------TLELEiAESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKAEAT-RLEKIK 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  917 LEAEDKlpPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSG------TDQLKALQSAKGALEEDL----RKCKQK 986
Cdd:NF033838  228 TDREKA--EEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGepatpdKKENDAKSSDSSVGEETLpspsLKPEKK 305

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  987 LSLAEgdvqrlkllngssSKVSELEQKLKRGDEEA---------KKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSK 1057
Cdd:NF033838  306 VAEAE-------------KKVEEAKKKAKDQKEEDrrnyptntyKTLELEIAESDVKVKEAELELVKEEAKEPRNEEKIK 372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1058 REKEKLSS-------LE------KDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQV 1124
Cdd:NF033838  373 QAKAKVESkkaeatrLEkiktdrKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQA 452

                         410
                  ....*....|....*....
gi 161076750 1125 Q-DLKKQVEEVQASLSAEQ 1142
Cdd:NF033838  453 EeDYARRSEEEYNRLTQQQ 471
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 825-1538 1.53e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   825 AEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKtGEVDQKmKESLAQAQRE 904
Cdd:TIGR02168  177 TERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELR-EELEEL-QEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   905 RDELTARLKRMQLEaedklpprtakrvndltpkshlkkwVEELEDEISEMRvMLSSSGTDQLKALQSAKGALEEDLRKCK 984
Cdd:TIGR02168  255 LEELTAELQELEEK-------------------------LEELRLEVSELE-EEIEELQKELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   985 QKL-----SLAEGDVQRLKLLngssSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKRE 1059
Cdd:TIGR02168  309 ERLanlerQLEELEAQLEELE----SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1060 KEKLSSLEKDMEKQAKEKEKLEAKISQLDAEllsakksaekskssLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLS 1139
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDR--------------RERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1140 AEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKIAEMDTIRIE---RTDMARKLSEAQKRIADLQA--- 1213
Cdd:TIGR02168  451 ELQEELERLEEALEELREE----LEEAEQALDAAERELAQLQARLDSLERLQENlegFSEGVKALLKNQSGLSGILGvls 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1214 ----------KALKTVNGNGAEY-----ERTVLKNKLAEKEHEYERL----------------RRENEMNIDLVFQLRKD 1262
Cdd:TIGR02168  527 elisvdegyeAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVtflpldsikgteiqgnDREILKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1263 N---------------------DDLNGKLSDYNRIEQAQS--SLNGHGAR------------------REAEIRELKEQ- 1300
Cdd:TIGR02168  607 LvkfdpklrkalsyllggvlvvDDLDNALELAKKLRPGYRivTLDGDLVRpggvitggsaktnssileRRREIEELEEKi 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1301 --LQSTELQMKSEVATVR---LRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTG-------- 1367
Cdd:TIGR02168  687 eeLEEKIAELEKALAELRkelEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEleaeieel 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1368 RQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVigsgstkl 1447
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER-------- 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1448 pgMKTKLELSWQKEREDQQRLLQETSTLARDLRQ-----TLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKkiaEL 1522
Cdd:TIGR02168  839 --RLEDLEEQIEELSEDIESLAAEIEELEELIEEleselEALLNERASLEEALALLRSELEELSEELRELESKRS---EL 913

                          810
                   ....*....|....*.
gi 161076750  1523 QCDLLELRDVHAKLRT 1538
Cdd:TIGR02168  914 RRELEELREKLAQLEL 929
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
768-1266 1.81e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 79.34  E-value: 1.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  768 LELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAE----KKVKTLNEELVQLRRTL 843
Cdd:PRK03918  226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkelKEKAEEYIKLSEFYEEY 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  844 TEKEQTVDSLKNQLS-KLDTLETENDKLAKENKRLLALRKASEKTgevdQKMKESLAQAQRERDELTARLKRMQLEAEDK 922
Cdd:PRK03918  306 LDELREIEKRLSRLEeEINGIEERIKELEEKEERLEELKKKLKEL----EKRLEELEERHELYEEAKAKKEELERLKKRL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  923 LPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGAlEEDLRKCKQKLSlaegDVQRLKLLNG 1002
Cdd:PRK03918  382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELT----EEHRKELLEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1003 SSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETS---KSTWESQSKREKEKLSSLEKDMEKQAKEKEK 1079
Cdd:PRK03918  457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqlKELEEKLKKYNLEELEKKAEEYEKLKEKLIK 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1080 LEAKISQLDAElLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNnhweklseet 1159
Cdd:PRK03918  537 LKGEIKSLKKE-LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYL---------- 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1160 ilmraQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKAlktvngNGAEYERtvLKNKLAEKE 1239
Cdd:PRK03918  606 -----ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY------SEEEYEE--LREEYLELS 672

                         490       500
                  ....*....|....*....|....*..
gi 161076750 1240 HEYERLRRENEMNIDLVFQLRKDNDDL 1266
Cdd:PRK03918  673 RELAGLRAELEELEKRREEIKKTLEKL 699
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 945-1561 4.23e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 4.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  945 EELEDEISEMRvmlsssgtDQLKAL--QSAK----GALEEDLRKCKQKLSLAEGDVQRLKL------LNGSSSKVSELEQ 1012
Cdd:COG1196   189 ERLEDILGELE--------RQLEPLerQAEKaeryRELKEELKELEAELLLLKLRELEAELeeleaeLEELEAELEELEA 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1013 KLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELl 1092
Cdd:COG1196   261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL- 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1093 sakksaekskSSLEKEIKDLKTKASKSDsKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQS 1172
Cdd:COG1196   340 ----------EELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1173 LQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKtvngngAEYERTVLKNKLAEKEHEYERLRRenemn 1252
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE------LEEEEEALLELLAELLEEAALLEA----- 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1253 idlvfQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELqmkSEVATVRLRYEQQVKNLSGELtS 1332
Cdd:COG1196   478 -----ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV---AVLIGVEAAYEAALEAALAAA-L 548

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1333 MQRQCERfkkdrdafkqmLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHL---------EDQLVESR 1403
Cdd:COG1196   549 QNIVVED-----------DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAvdlvasdlrEADARYYV 617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1404 LESSKIKTELVSERSANEIKIS-EMQSKLNEFEEERVIGSGSTKLPGMKTKLELswQKEREDQQRLLQETSTLARDLRQT 1482
Cdd:COG1196   618 LGDTLLGRTLVAARLEAALRRAvTLAGRLREVTLEGEGGSAGGSLTGGSRRELL--AALLEAEAELEELAERLAEEELEL 695

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1483 LFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCDLLELRDVHAKLRTSNEKLRRERErye----keLIKRR 1558
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDleelereleRLERE 775


                  ...
gi 161076750 1559 MEA 1561
Cdd:COG1196   776 IEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 348-1087 7.11e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 7.11e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAErEKSDILLRRLASMDTASNRtaasealnLQQKLNEMKEQLDRVTEDKRKLNLRMKELE 427
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELE-EKLEELRLEVSELEEEIEE--------LQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   428 NkgSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDtfrddEVKAKTSLQKDLEKATKNCRILSfkLKKSD 507
Cdd:TIGR02168  316 R--QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA-----ELEELEAELEELESRLEELEEQL--ETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   508 RKIETLEQERQssfnaeLSNKIKKLEEELRFSNELTRKLQAEAEELRNpgkkkapmlgvlgKSTSADAKFTRESLtrGGS 587
Cdd:TIGR02168  387 KVAQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLK-------------KLEEAELKELQAEL--EEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   588 QEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERkRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMST---- 663
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   664 ---------------------SVENLVTSNVAVTQTDFEVpDRNVSIERETMS--SPFAGLFPPSSSSRVGQSGSLLFPS 720
Cdd:TIGR02168  525 lselisvdegyeaaieaalggRLQAVVVENLNAAKKAIAF-LKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   721 AISHV------------LLSG---------AGRKLSPTPHPHRLapeVHAD-----RDEGISDEDDPAELRIL-----LE 769
Cdd:TIGR02168  604 AKDLVkfdpklrkalsyLLGGvlvvddldnALELAKKLRPGYRI---VTLDgdlvrPGGVITGGSAKTNSSILerrreIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   770 LNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQdssngskssllsLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQT 849
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQ------------LRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   850 VDSLKNQLSKLDTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKlpprTA 928
Cdd:TIGR02168  749 IAQLSKELTELEAEIEElEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL----RE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   929 KRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSgTDQLKALQSAKGALEEDL-RKCKQKLSLAEGDVQRLKLLNGSSSKV 1007
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1008 SELEQKLKRGDEEAKKLNSKLKDLEdkVKKQEAQLKLGETSKSTWESQSKRE---KEKLSSLEKDMEKQAKEKEKLEAKI 1084
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLE--LRLEGLEVRIDNLQERLSEEYSLTLeeaEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 161076750  1085 SQL 1087
Cdd:TIGR02168  982 KEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 864-1466 1.68e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  864 ETENDKLAKENKRLLALRKASEKTGEVDQKMKESL-AQAQRERDELtaRLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKK 942
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIkAEEARKADEL--KKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  943 WVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDlRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKL---KRGDE 1019
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA-EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKaeeKKKAD 1394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1020 EAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAE 1099
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1100 KSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEV----QASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQA 1175
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKkkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1176 E--LNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEYERTVLKnKLAEKEHEYERLRRENEMNi 1253
Cdd:PTZ00121 1555 EelKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK-KAEEAKIKAEELKKAEEEK- 1632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1254 DLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKnlsgeLTSM 1333
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-----AEEL 1707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1334 QRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQighLEDQLVESRLESSKIKTEL 1413
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE---EEKKAEEIRKEKEAVIEEE 1784

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 161076750 1414 VSERSANEIKISEMQSKlNEFEEERVIGSGstklpGMKTKLELSWQKEREDQQ 1466
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIK-DIFDNFANIIEG-----GKEGNLVINDSKEMEDSA 1831
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 400-1237 6.34e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.24  E-value: 6.34e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   400 QKLNEMKEQLDRVteDKRKLNLRMKELENKgsESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFrDDEV 479
Cdd:TIGR02168  213 ERYKELKAELREL--ELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI-EELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   480 KAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQssfnaELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKK 559
Cdd:TIGR02168  288 KELYALANEISRLEQQKQILRERLANLERQLEELEAQLE-----ELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   560 KAPMLGVLgKSTSADAkftresltrggsQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKrvrfscgTQTE 639
Cdd:TIGR02168  363 LEAELEEL-ESRLEEL------------EEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER-------LQQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   640 VPLEVVAFPRgtqtvatvqSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAGLFPPSSSSRVGQSGSLLFP 719
Cdd:TIGR02168  423 IEELLKKLEE---------AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   720 SAISHVLLSGAGRKLSPTPHPHRLAPEVHADRDEGIS-DEDDPAELRILLELNEQeasilrlkveDLEKENAESkkyVRE 798
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvDEGYEAAIEAALGGRLQ----------AVVVENLNA---AKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   799 LQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEE------LVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAK 872
Cdd:TIGR02168  561 AIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIegflgvAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   873 ENKRLLALRKASEK-------TGEVDQKMKESLAQaQRERDELTARLKRMQLEAEDklpprtakrvndltpkshLKKWVE 945
Cdd:TIGR02168  641 LRPGYRIVTLDGDLvrpggviTGGSAKTNSSILER-RREIEELEEKIEELEEKIAE------------------LEKALA 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   946 ELEDEISEMRvmlsssgtDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRL-KLLNGSSSKVSELEQKLKRGDEEAKKL 1024
Cdd:TIGR02168  702 ELRKELEELE--------EELEQLRKELEELSRQISALRKDLARLEAEVEQLeERIAQLSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1025 NSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE---LLSAKKSAEKS 1101
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRledLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1102 KSSLEKEIKDLKTKASKSdSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASK 1181
Cdd:TIGR02168  854 IESLAAEIEELEELIEEL-ESELEALLNERASLEEALALLRSELEELSEELRELESK----RSELRRELEELREKLAQLE 928

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 161076750  1182 QKIAEmdtIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEYERTV--LKNKLAE 1237
Cdd:TIGR02168  929 LRLEG---LEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLkrLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 756-1351 7.51e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 7.51e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   756 SDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLrqdssngsksslLSLGTSSSAAEKKVKTLNEE 835
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL------------EELEAELEELESRLEELEEQ 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   836 LVQLRRTLTEKEQTVDSLKNQLSKLDT----LETENDKLAKENKRLL--ALRKASEKTGEVDQKMKESLAQAQRERDELT 909
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEArlerLEDRRERLQQEIEELLkkLEEAELKELQAELEELEEELEELQEELERLE 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   910 ARLKRMQLEAEDKLPPRTAKRvNDLTPKSHLKKWVEELEDEISEM-----RVMLSSSGTDQLKALQSAK--------GAL 976
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAE-RELAQLQARLDSLERLQENLEGFsegvkALLKNQSGLSGILGVLSELisvdegyeAAI 539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   977 EEDLRKCKQKL-------------SLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQE---- 1039
Cdd:TIGR02168  540 EAALGGRLQAVvvenlnaakkaiaFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkals 619

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1040 ----------------AQLKL-----------GETSKSTWESQSKREKEKLSSLEKD--MEKQAKEKEKLEAKISQLDAE 1090
Cdd:TIGR02168  620 yllggvlvvddldnalELAKKlrpgyrivtldGDLVRPGGVITGGSAKTNSSILERRreIEELEEKIEELEEKIAELEKA 699

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1091 LlsakKSAEKSKSSLEKEIKDLKtKASKSDSKQVQDLKKQVEEvqasLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEK 1170
Cdd:TIGR02168  700 L----AELRKELEELEEELEQLR-KELEELSRQISALRKDLAR----LEAEVEQLEERIAQLSKELTELEAEIEELEERL 770

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1171 QSLQAELNASKQKI----AEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGngaeyeRTVLKNKLAEKEHEYERLR 1246
Cdd:TIGR02168  771 EEAEEELAEAEAEIeeleAQIEQLKEELKALREALDELRAELTLLNEEAANLRER------LESLERRIAATERRLEDLE 844

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1247 RENEmnidlvfQLRKDNDDLNGKLSDYNR-IEQAQSSLNGHGARR---EAEIRELKEQLQSTELQMKsEVATVRLRYEQQ 1322
Cdd:TIGR02168  845 EQIE-------ELSEDIESLAAEIEELEElIEELESELEALLNERaslEEALALLRSELEELSEELR-ELESKRSELRRE 916

                          650       660
                   ....*....|....*....|....*....
gi 161076750  1323 VKNLSGELTSMQRQCERFKKDRDAFKQML 1351
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 347-1090 8.38e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 8.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   347 MQEQMKALKLELETMKTRAEKAEREKSdILLRRLASMDTASNRTAAsEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKEL 426
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEA-QLEELESKLDELAEELAELEEKLEELKEELESL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   427 ENKgsESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKaKTSLQKDLEKATKNCRILSFKLKKS 506
Cdd:TIGR02168  357 EAE--LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR-LERLEDRRERLQQEIEELLKKLEEA 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   507 DRK-----IETLEQERQS--SFNAELSNKIKKLEEELRFSNELTRKLQAEAEELR------------------------N 555
Cdd:TIGR02168  434 ELKelqaeLEELEEELEElqEELERLEEALEELREELEEAEQALDAAERELAQLQarldslerlqenlegfsegvkallK 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   556 PGKKKAPMLGVLGKSTSADAKFTRESLTRGGSqedpqHLQRELQDSieretdlkdqLKFAEEELQRLRDRERKRVRFSCG 635
Cdd:TIGR02168  514 NQSGLSGILGVLSELISVDEGYEAAIEAALGG-----RLQAVVVEN----------LNAAKKAIAFLKQNELGRVTFLPL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   636 TQ------TEVPLEVVAFPRGTQTVATVQSDMSTSVENLVT---SNVAVTQTdfevPDRNVSIERETmsspfaglfpPSS 706
Cdd:TIGR02168  579 DSikgteiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllGGVLVVDD----LDNALELAKKL----------RPG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   707 SSRVGQSGSLLFPSAishVLLSGAGRKLSPTPHPHRLAPEVHADRDEGISDEDDP----AELRILLELNEQEASILRLKV 782
Cdd:TIGR02168  645 YRIVTLDGDLVRPGG---VITGGSAKTNSSILERRREIEELEEKIEELEEKIAELekalAELRKELEELEEELEQLRKEL 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   783 EDLEKENAESKKYVRELQAKLRQ--DSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKL 860
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQleERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   861 DTletendKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEdklppRTAKRVNDL-TPKSH 939
Cdd:TIGR02168  802 RE------ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE-----SLAAEIEELeELIEE 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   940 LKKWVEELEDEISEMRVMLSS------SGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKL-LNGSSSKVSELEQ 1012
Cdd:TIGR02168  871 LESELEALLNERASLEEALALlrseleELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVrIDNLQERLSEEYS 950

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1013 KLKRGDEE-AKKLNSKLKDLEDKVKKQEAQLK-LGETSKSTWEsQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE 1090
Cdd:TIGR02168  951 LTLEEAEAlENKIEDDEEEARRRLKRLENKIKeLGPVNLAAIE-EYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 769-1510 1.32e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   769 ELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRqdssngskssllslgtsssAAEKKVKTLNEELVQLRRTLTEKEQ 848
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELE-------------------ELTAELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   849 TVDS----LKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLP 924
Cdd:TIGR02168  282 EIEElqkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   925 PRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSgTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLlngss 1004
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASL-NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL----- 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1005 skvSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDME---------KQAK 1075
Cdd:TIGR02168  436 ---KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEnlegfsegvKALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1076 EKEKLEAKISQLDAELLSAKKS-AEKSKSSLEKEIKDLKTKaSKSDSKQVQDLKKQVEEVQASLSAE--QKRYEDLNNHW 1152
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGyEAAIEAALGGRLQAVVVE-NLNAAKKAIAFLKQNELGRVTFLPLdsIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1153 EKLSEETILMRAQLTTEK-------------------QSLQAELNASKQKIAEM-------DTIRI--------ERTDMA 1198
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPggvitggsAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1199 -----RKLSEAQKRIADLQAK-ALKTVNGNGAEYERTVLKNKLAEKEHEYERLRRE-NEMNIDLVF------QLRKDNDD 1265
Cdd:TIGR02168  672 ilerrREIEELEEKIEELEEKiAELEKALAELRKELEELEEELEQLRKELEELSRQiSALRKDLARleaeveQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1266 LNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRY---EQQVKNLSGELTSMQRQCERFKK 1342
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALdelRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1343 DRDAFKQMLEVAQKKIGDLkanntgRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSanei 1422
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEEL------SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE---- 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1423 KISEMQSKLNEFEEERvigsgsTKLPGMKTKLELSWQKEREDQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLD 1502
Cdd:TIGR02168  902 ELRELESKRSELRREL------EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   ....*...
gi 161076750  1503 QIKRATEE 1510
Cdd:TIGR02168  976 RLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1034-1363 2.29e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.29e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1034 KVKKQEAQLKLGETSKSTwesqsKREKEKLSSLEKDM---EKQAKEKEK---LEAKISQLDAELL--------SAKKSAE 1099
Cdd:TIGR02168  171 KERRKETERKLERTRENL-----DRLEDILNELERQLkslERQAEKAERykeLKAELRELELALLvlrleelrEELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1100 KSKSSLEKEIKDLKTKASKSDSkQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMR---AQLTTEKQSLQAE 1176
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEE-KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRerlANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1177 LNASKQKIaemDTIRIERTDMARKLSEAQKRIADLQAKALKtvngngAEYERTVLKNKLAEKEHEYERLRREnemnidlV 1256
Cdd:TIGR02168  325 LEELESKL---DELAEELAELEEKLEELKEELESLEAELEE------LEAELEELESRLEELEEQLETLRSK-------V 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1257 FQLRKDNDDLNGKLSdynRIEQAQSSLNGHGARREAEIRELKEQLQSTELQmksEVATVRLRYEQQVKNLSGELTSMQRQ 1336
Cdd:TIGR02168  389 AQLELQIASLNNEIE---RLEARLERLEDRRERLQQEIEELLKKLEEAELK---ELQAELEELEEELEELQEELERLEEA 462

                          330       340
                   ....*....|....*....|....*..
gi 161076750  1337 CERFKKDRDAFKQMLEVAQKKIGDLKA 1363
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQA 489
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 762-1087 2.36e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.33  E-value: 2.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   762 AELRILLELNEQEASILRLKVEDLEKENAESKKYvRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRR 841
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   842 TLTEKEQTVDSLknqLSKLDTLETENDKLAKENKRLLAlRKASEKTGEVDQ------KMKESLAQAQRERDELTARLKRM 915
Cdd:TIGR02169  259 EISELEKRLEEI---EQLLEELNKKIKDLGEEEQLRVK-EKIGELEAEIASlersiaEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   916 QLEAEDKLPPRTAKRVNdltpKSHLKKWVEELEDEISEMRVMLSSSGTDqLKALQSAKGALEEDLRKCKQKLSLAEGDVQ 995
Cdd:TIGR02169  335 LAEIEELEREIEEERKR----RDKLTEEYAELKEELEDLRAELEEVDKE-FAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   996 RL-KLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQA 1074
Cdd:TIGR02169  410 RLqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          330
                   ....*....|...
gi 161076750  1075 KEKEKLEAKISQL 1087
Cdd:TIGR02169  490 RELAEAEAQARAS 502
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 826-1362 2.76e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.89  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   826 EKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKTgevDQKMKESLAQAQRER 905
Cdd:TIGR04523  165 KKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQ---NNQLKDNIEKKQQEI 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   906 DELTARLKRMQleaedklpprtaKRVNDLtpKSHLKKWVEELEDEISEMRVM--LSSSGTDQLKALQSAKGAL----EED 979
Cdd:TIGR04523  242 NEKTTEISNTQ------------TQLNQL--KDEQNKIKKQLSEKQKELEQNnkKIKELEKQLNQLKSEISDLnnqkEQD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   980 LRKC-KQKLSLAEGDVQRLKL-LNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSK 1057
Cdd:TIGR04523  308 WNKElKSELKNQEKKLEEIQNqISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIK 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1058 REKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaekskSSLEKEIKDLKTKASKSDSkQVQDLKKQVeevqas 1137
Cdd:TIGR04523  388 NLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK-----------ELLEKEIERLKETIIKNNS-EIKDLTNQD------ 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1138 lSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALK 1217
Cdd:TIGR04523  450 -SVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1218 tvngngaeyertvLKNKLAEKEHEYERLRRE-NEMNIDLVF-QLRKDNDDLNGKLS----DYNRIEQAQSSLNGHGARRE 1291
Cdd:TIGR04523  529 -------------LESEKKEKESKISDLEDElNKDDFELKKeNLEKEIDEKNKEIEelkqTQKSLKKKQEEKQELIDQKE 595

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161076750  1292 AEIRELKEQLQSTE---LQMKSEVATVRLRYE---QQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLK 1362
Cdd:TIGR04523  596 KEKKDLIKEIEEKEkkiSSLEKELEKAKKENEklsSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESK 672
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 350-915 2.90e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 2.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  350 QMKALKLELETMKTRAEKAEREKSDIllrrlasmdTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENK 429
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEEL---------EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  430 gsESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSfKLKKSDRK 509
Cdd:COG1196   304 --IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA-ELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  510 IETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRnpgkKKAPMLGVLGKSTSADAKFTRESLTRGGSQE 589
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE----LEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  590 DPQHLQRELQDSIERETDLKDQLkfAEEELQRLRDRERKRVRFSCGTQTEVPLEVVAF-------PRGTQTVATVQSDMS 662
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAAL--AELLEELAEAAARLLLLLEAEADYEGFLEGVKAalllaglRGLAGAVAVLIGVEA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  663 TSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAG--LFPPSSSSRVGQSGSLLFPSAISHVLLSGAGRKLSPTPHP 740
Cdd:COG1196   535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  741 HRLAPEVHADRDegiSDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGT 820
Cdd:COG1196   615 YYVLGDTLLGRT---LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  821 SSSAAEKKVKTLNEELVQLRRTLTEKEQtvdslknQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQ 900
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEE-------ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                         570
                  ....*....|....*
gi 161076750  901 AQRERDELTARLKRM 915
Cdd:COG1196   765 LERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 977-1346 8.24e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 8.24e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   977 EEDLRKCKQKLSLAEGDVQRLKLLngssskVSELEQKLKRGDEEAKKLnSKLKDLEDKVKKQEAQLKLGEtsKSTWESQS 1056
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLI------IDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELLKE--KEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1057 KREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaekskSSLEKEIKDLktkaskSDSKQVQdLKKQVEEVQA 1136
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLL-----------EELNKKIKDL------GEEEQLR-VKEKIGELEA 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1137 SLSAEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKIAEMdtiRIERTDMARKLSEAQKRIADLQAKAL 1216
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEER----LAKLEAEIDKLLAEIEELEREIEEE---RKRRDKLTEEYAELKEELEDLRAELE 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1217 KTVNGNGAEYERTV-LKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSdynRIEQAQSSLNGHGARREAEIR 1295
Cdd:TIGR02169  375 EVDKEFAETRDELKdYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA---GIEAKINELEEEKEDKALEIK 451

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 161076750  1296 ELKEQLQSTELQMKSEVATVRlRYEQQVKNLSGELTSMQRQCERFKKDRDA 1346
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELY-DLKEEYDRVEKELSKLQRELAEAEAQARA 501
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
826-1342 9.96e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.01  E-value: 9.96e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  826 EKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEktgevdqKMKESLAQAQRER 905
Cdd:PRK03918  206 LREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE-------ERIEELKKEIEEL 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  906 DELTARLKRMQLEAEDKLPPRtAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSssgtdQLKALQSAKGALEEDLRKCKQ 985
Cdd:PRK03918  279 EEKVKELKELKEKAEEYIKLS-EFYEEYLDELREIEKRLSRLEEEINGIEERIK-----ELEEKEERLEELKKKLKELEK 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  986 KLSLAEGDVqrlKLLNGSSSKVSELEQ-KLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLS 1064
Cdd:PRK03918  353 RLEELEERH---ELYEEAKAKKEELERlKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1065 SLEK------------DMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVE 1132
Cdd:PRK03918  430 ELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELE 509

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1133 EVQASLSAEQkrYEDLNNHWEKLSEETILMRAQLttekQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQ 1212
Cdd:PRK03918  510 EKLKKYNLEE--LEKKAEEYEKLKEKLIKLKGEI----KSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1213 AKALKTVNGNGAE----YERTV-LKNKLAEKEHEYERLRRENE------MNIDLVF----QLRKDNDDLNGKLSD--YNR 1275
Cdd:PRK03918  584 FESVEELEERLKElepfYNEYLeLKDAEKELEREEKELKKLEEeldkafEELAETEkrleELRKELEELEKKYSEeeYEE 663

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1276 IEQAQSSLNGHGARREAEIRELKEQLQSTEL---QMKSEVATVRlRYEQQVKNLSGELTSMQRQCERFKK 1342
Cdd:PRK03918  664 LREEYLELSRELAGLRAELEELEKRREEIKKtleKLKEELEERE-KAKKELEKLEKALERVEELREKVKK 732
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1034-1363 2.10e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 2.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1034 KVKKQEAQLKLGETskstwesQSK--------REKEK-LSSLEKDMEKqAKEKEKLEAKISQLDAELLSAKKSAEKSKSS 1104
Cdd:COG1196   171 KERKEEAERKLEAT-------EENlerledilGELERqLEPLERQAEK-AERYRELKEELKELEAELLLLKLRELEAELE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1105 LEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKI 1184
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1185 AEMDTiriERTDMARKLSEAQKRIADLQAKALKtvngngAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDN- 1263
Cdd:COG1196   319 EELEE---ELAELEEELEELEEELEELEEELEE------AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELl 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1264 ---DDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVR------LRYEQQVKNLSGELTSMQ 1334
Cdd:COG1196   390 ealRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEeaaeeeAELEEEEEALLELLAELL 469

                         330       340
                  ....*....|....*....|....*....
gi 161076750 1335 RQCERFKKDRDAFKQMLEVAQKKIGDLKA 1363
Cdd:COG1196   470 EEAALLEAALAELLEELAEAAARLLLLLE 498
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1014-1531 2.70e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.43  E-value: 2.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1014 LKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEK---DMEKQAKEKEKLEAKISqldaE 1090
Cdd:TIGR04523  147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELllsNLKKKIQKNKSLESQIS----E 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1091 LLSAKKSAEKSKSSLEKEIKDLKTKASKSDsKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEK 1170
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEKTTEISNTQ-TQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1171 QslQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADL--QAKALKTvNGNGAEYERTVLKNKLAEKEHEYERLRRE 1248
Cdd:TIGR04523  302 N--QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLneQISQLKK-ELTNSESENSEKQRELEEKQNEIEKLKKE 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1249 NEMNIDLVFQLRKDNDDLNGKLSDYNRIEQaqsslnghgaRREAEIRELKEQLQSTELQMKSEVATvRLRYEQQVKNLSG 1328
Cdd:TIGR04523  379 NQSYKQEIKNLESQINDLESKIQNQEKLNQ----------QKDEQIKKLQQEKELLEKEIERLKET-IIKNNSEIKDLTN 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1329 ELTSMQRQCERFKKDRDAFKQMLEVAQKKIG----DLKANNTGRQSRGSMHSSDDDDKSKiayLEQQIGHLEDQLVESRl 1404
Cdd:TIGR04523  448 QDSVKELIIKNLDNTRESLETQLKVLSRSINkikqNLEQKQKELKSKEKELKKLNEEKKE---LEEKVKDLTKKISSLK- 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1405 esSKIKtELVSERSANEIKISEMQSKLNEFEEErvigsgstklpgmKTKLELSWQKEREDQQRllqetstlardlrqtlf 1484
Cdd:TIGR04523  524 --EKIE-KLESEKKEKESKISDLEDELNKDDFE-------------LKKENLEKEIDEKNKEI----------------- 570

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 161076750  1485 eVERERDKERLESK-RKLDQIKRATEEEMEEGRKKIAELQCDLLELRD 1531
Cdd:TIGR04523  571 -EELKQTQKSLKKKqEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEK 617
PTZ00121 PTZ00121
MAEBL; Provisional
 858-1523 9.69e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 9.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  858 SKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDlTPK 937
Cdd:PTZ00121 1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED-ARK 1165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  938 SHLKKWVEELEdEISEMRVMLSSSGTDQLKALQSAKGAleEDLRKCKQKLSLAEgdVQRLKllngSSSKVSELE--QKLK 1015
Cdd:PTZ00121 1166 AEEARKAEDAK-KAEAARKAEEVRKAEELRKAEDARKA--EAARKAEEERKAEE--ARKAE----DAKKAEAVKkaEEAK 1236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1016 RGDEEAKKLnSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAK 1095
Cdd:PTZ00121 1237 KDAEEAKKA-EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1096 KSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEV---QASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQS 1172
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAaadEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE 1395

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1173 LQAELNASKQKIAEMDTIRIE--RTDMARKLSEAQKRIADLQAKALKTVNGNGA-----EYERTVLKNKLAEKEHEYERL 1245
Cdd:PTZ00121 1396 AKKKAEEDKKKADELKKAAAAkkKADEAKKKAEEKKKADEAKKKAEEAKKADEAkkkaeEAKKAEEAKKKAEEAKKADEA 1475

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1246 RRENEmNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLN----GHGARREAEIRELKEQLQSTELQMKSEVATV-RLRYE 1320
Cdd:PTZ00121 1476 KKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADeakkAEEAKKADEAKKAEEAKKADEAKKAEEKKKAdELKKA 1554

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1321 QQVKNlsGELTSMQRQCERFKKDRDAFKQMLEVAQK-------KIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIG 1393
Cdd:PTZ00121 1555 EELKK--AEEKKKAEEAKKAEEDKNMALRKAEEAKKaeearieEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1394 HLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLnefEEERVIGSGSTKLPGMKTKLELSWQKEREDQQRLLQETS 1473
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....
gi 161076750 1474 TLARDLRQT--LFEVERERDKERLESKRKLDQIKRATEE--EMEEGRKKIAELQ 1523
Cdd:PTZ00121 1710 KEAEEKKKAeeLKKAEEENKIKAEEAKKEAEEDKKKAEEakKDEEEKKKIAHLK 1763
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1006-1528 1.07e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1006 KVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKlgetskstwesQSKREKEKLSSLEKDMEKQAKEKEKLEAKIS 1085
Cdd:PRK03918  194 LIKEKEKELEEVLREINEISSELPELREELEKLEKEVK-----------ELEELKEEIEELEKELESLEGSKRKLEEKIR 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1086 QLDaELLSAKKSAEKSKSSLEKEIKDLKTKASK---------SDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLS 1156
Cdd:PRK03918  263 ELE-ERIEELKKEIEELEEKVKELKELKEKAEEyiklsefyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1157 E------------ETILMRAQLTTEKQSLQAELNASKQKIA---------EMDTIRIERTDMARKLSEAQKRIADLQAK- 1214
Cdd:PRK03918  342 ElkkklkelekrlEELEERHELYEEAKAKKEELERLKKRLTgltpeklekELEELEKAKEEIEEEISKITARIGELKKEi 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1215 --------ALKTVNGN----GAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSS 1282
Cdd:PRK03918  422 kelkkaieELKKAKGKcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKEL 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1283 LNghgarreaEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKkdrdAFKQMLEVAQKKIGDL- 1361
Cdd:PRK03918  502 AE--------QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE----ELKKKLAELEKKLDELe 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1362 -KANNTGRQSRGSMHSSDDDDKSKIAYLE--------------------QQIGHLEDQLVESRLESSKIKTELVSERSan 1420
Cdd:PRK03918  570 eELAELLKELEELGFESVEELEERLKELEpfyneylelkdaekelereeKELKKLEEELDKAFEELAETEKRLEELRK-- 647

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1421 eiKISEMQSKLNEFEEERvigsgstkLPGMKTKLELSWQKEREDQQRLLQETSTLARDLRQTlfeveRERDKERLESKRK 1500
Cdd:PRK03918  648 --ELEELEKKYSEEEYEE--------LREEYLELSRELAGLRAELEELEKRREEIKKTLEKL-----KEELEEREKAKKE 712

                         570       580
                  ....*....|....*....|....*...
gi 161076750 1501 LDQIKRATeEEMEEGRKKIAELQCDLLE 1528
Cdd:PRK03918  713 LEKLEKAL-ERVEELREKVKKYKALLKE 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 893-1578 1.86e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 1.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   893 KMKESLAQAQRERDELTARLKRMQLEAEdklpprTAKRVNDLtpkshlKKWVEELEDEISEMRVmlsSSGTDQLKALQSA 972
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAE------KAERYKEL------KAELRELELALLVLRL---EELREELEELQEE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   973 KGALEEDLRKCKQKLSLAEGDVQRLKLlngsssKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTW 1052
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRL------EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1053 ESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKsdskqVQDLKKQVE 1132
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSK-----VAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1133 EVQASLSAEQKRYEDLNNHWEKLSEET-ILMRAQLTTEKQSLQAELNASKQKIAEMDTiriERTDMARKLSEAQKRIADL 1211
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIeELLKKLEEAELKELQAELEELEEELEELQE---ELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1212 QAK----------------ALKTVNGNGAEYERTVLKNKLAEK---------------EHEYER------------LRRE 1248
Cdd:TIGR02168  474 EQAldaaerelaqlqarldSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvDEGYEAaieaalggrlqaVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1249 NEMNIDLVFQLRKDN----------DDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQL----------------Q 1302
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNelgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddldN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1303 STELQMK-------------------------SEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKK 1357
Cdd:TIGR02168  634 ALELAKKlrpgyrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1358 IGDLkanntgRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESskikTELVSERSANEIKISEMQSKLNEFEEE 1437
Cdd:TIGR02168  714 LEQL------RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL----TELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1438 RVigsgstKLPGMKTKLELSWQKEREDQQRLLQETSTLARDLRQTLFEVERERDKERLESKR--KLDQIKRATEEEMEEG 1515
Cdd:TIGR02168  784 IE------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRleDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161076750  1516 RKKIAELQCDLLELRDVHAKLRTSNEKLRRERERYEKELIKRRMEADGGDRKVGALLQTVDEL 1578
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1006-1536 1.99e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 1.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1006 KVSELEQKLKRGDEEAKKLNSKLKDL----EDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLE 1081
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLrrerEKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1082 AKISQLDAELlsakksaekskSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEEtil 1161
Cdd:TIGR02169  258 EEISELEKRL-----------EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER--- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1162 mRAQLTTEKQSLQAELNASKQKIAEMdtiRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEYERTV-LKNKLAEKEH 1240
Cdd:TIGR02169  324 -LAKLEAEIDKLLAEIEELEREIEEE---RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdYREKLEKLKR 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1241 EYERLRRENEMNIDLVFQLRKDNDDLNGKLSdynRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRlRYE 1320
Cdd:TIGR02169  400 EINELKRELDRLQEELQRLSEELADLNAAIA---GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY-DLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1321 QQVKNLSGELTSMQRQCERFKKDRDAFKQ----------MLE-------------------------------------- 1352
Cdd:TIGR02169  476 EEYDRVEKELSKLQRELAEAEAQARASEErvrggraveeVLKasiqgvhgtvaqlgsvgeryataievaagnrlnnvvve 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1353 ---VAQKKIGDLKANNTGRQS-----RGSMHSSDDDDKSKIAYLEQQIGHLE--------------DQLVESRLESSK-- 1408
Cdd:TIGR02169  556 ddaVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEDGVIGFAVDLVEfdpkyepafkyvfgDTLVVEDIEAARrl 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1409 -IKTELVS------ERS------ANEIKISEMQSKLNEFEEERVigsgSTKLPGMKTKLElSWQKEREDQQRLLQETSTL 1475
Cdd:TIGR02169  636 mGKYRMVTlegelfEKSgamtggSRAPRGGILFSRSEPAELQRL----RERLEGLKRELS-SLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 161076750  1476 ARDLRQTLFEVERERD---------KERLE-SKRKLDQIKRATEE---EMEEGRKKIAELQCDLLELRDVHAKL 1536
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEqleqeeeklKERLEeLEEDLSSLEQEIENvksELKELEARIEELEEDLHKLEEALNDL 784
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 768-1210 3.51e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.96  E-value: 3.51e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   768 LELNEQEASILRLKVEDLEKENAESKKYVRELQAKLrQDSSNGSKSSLLSLGTSSSAAEKKVKTLNE---ELVQLRRTLT 844
Cdd:TIGR04523  206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEI-NEKTTEISNTQTQLNQLKDEQNKIKKQLSEkqkELEQNNKKIK 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   845 EKEQTVDSLKNQLSKL------DTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLE 918
Cdd:TIGR04523  285 ELEKQLNQLKSEISDLnnqkeqDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   919 AEDKLPP-RTAKRVND--LTPKSHLKKWVEELEDEISEMRVmLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQ 995
Cdd:TIGR04523  365 LEEKQNEiEKLKKENQsyKQEIKNLESQINDLESKIQNQEK-LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   996 RLK--------LLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLE 1067
Cdd:TIGR04523  444 DLTnqdsvkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1068 KDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSK-----SSLEKEIKDLK--TKASKSDSKQVQDLKKQVEEVQASLSA 1140
Cdd:TIGR04523  524 EKIEKLESEKKEKESKISDLEDELNKDDFELKKENlekeiDEKNKEIEELKqtQKSLKKKQEEKQELIDQKEKEKKDLIK 603

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 161076750  1141 EQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIA----EMDTIRIERTDMARKLSEAQKRIAD 1210
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKqikeTIKEIRNKWPEIIKKIKESKTKIDD 677
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 834-1191 4.40e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   834 EELVQLRRTLTEKEQTVDSLKNQLSKLDTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELT--- 909
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDElSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEqei 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   910 ARLKRMQLEAEDKLPPRTAKrvndltpkshlkkwVEELEDEISEMRVMLSSSGTDQLKALQSAkgaLEEDLRKCKQKLSL 989
Cdd:TIGR02169  754 ENVKSELKELEARIEELEED--------------LHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLRE 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   990 AEGDVQRLkllngssskvselEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKD 1069
Cdd:TIGR02169  817 IEQKLNRL-------------TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1070 MEKQAKEKEKLEAKISQLDAELlsakKSAEKSKSSLEKEIKDLKTKAS----------------KSDSKQVQDLKKQVEE 1133
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKI----EELEAQIEKKRKRLSELKAKLEaleeelseiedpkgedEEIPEEELSLEDVQAE 959

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 161076750  1134 VQAsLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIR 1191
Cdd:TIGR02169  960 LQR-VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 762-1346 5.64e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 5.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  762 AELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQdssngSKSSLLSLGTSSSAAEKKVKTLNEELVQLRR 841
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE-----AQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  842 TLTEKEQTVDSLKNQlskLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAED 921
Cdd:COG1196   317 RLEELEEELAELEEE---LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  922 KLpprtakrvndltpkshlkkwvEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLN 1001
Cdd:COG1196   394 AA---------------------AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1002 GSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLgetskstwesqsKREKEKLSSLEKDMEKQAKEKEKLE 1081
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL------------LLEAEADYEGFLEGVKAALLLAGLR 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1082 AKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNhwEKLSEETIL 1161
Cdd:COG1196   521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA--AALARGAIG 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1162 MRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEYERTVLKNKLAEKEHE 1241
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1242 yERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRYEQ 1321
Cdd:COG1196   679 -AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                         570       580
                  ....*....|....*....|....*
gi 161076750 1322 QVKNLSgeltSMQRQCERFKKDRDA 1346
Cdd:COG1196   758 EPPDLE----ELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 866-1582 5.77e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 5.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  866 ENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVE 945
Cdd:PTZ00121 1119 EAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAED 1198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  946 ----------ELEDEISEMRVMLSSSGTDQLKALQSAKGAlEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLK 1015
Cdd:PTZ00121 1199 arkaeaarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA 1277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1016 RGDEEAKKLNSKLKdlEDKVKKQEAQLKLGETSKstwESQSKREKEKLSSLEKDMEKQAKEKEKlEAKISQLDAELLSAK 1095
Cdd:PTZ00121 1278 RKADELKKAEEKKK--ADEAKKAEEKKKADEAKK---KAEEAKKADEAKKKAEEAKKKADAAKK-KAEEAKKAAEAAKAE 1351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1096 KSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQA 1175
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKK 1431

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1176 ELNASKQKIAEMdtiriERTDMARKLSEAQKRIADLQAKAlktvngngAEYERTVLKNKLAEKEHEYERLRRENEmnidl 1255
Cdd:PTZ00121 1432 KADEAKKKAEEA-----KKADEAKKKAEEAKKAEEAKKKA--------EEAKKADEAKKKAEEAKKADEAKKKAE----- 1493

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1256 vfQLRKDNDDLNGKLSDYNRIEQAQSSlngHGARREAEIRELKEQLQSTELQMKSEVatvrlRYEQQVknlsgeltsmqR 1335
Cdd:PTZ00121 1494 --EAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKADEAKKAEEK-----KKADEL-----------K 1552

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1336 QCERFKKDRDAFKqmleVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLveSRLESSKIKTELVs 1415
Cdd:PTZ00121 1553 KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA--KKAEEAKIKAEEL- 1625

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1416 eRSANEIKISEMQSKLNEFEEERvigsgstklpgmktKLELSWQKEREDQQRLLQETSTLARDLRQTlfeveRERDKERL 1495
Cdd:PTZ00121 1626 -KKAEEEKKKVEQLKKKEAEEKK--------------KAEELKKAEEENKIKAAEEAKKAEEDKKKA-----EEAKKAEE 1685

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1496 ESKRKLDQIKRATEE--EMEEGRKKIAELQCDLLELRdvhaklrtsneklrRERERYEKELIKRRMEADGGDRKVGALLQ 1573
Cdd:PTZ00121 1686 DEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK--------------KAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751


                  ....*....
gi 161076750 1574 TVDELVKIA 1582
Cdd:PTZ00121 1752 DEEEKKKIA 1760
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 397-1278 7.31e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 7.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   397 NLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELRRK-------LQAAEQICEE---LMEENQSAKKEILNLQAE 466
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKkaleyyqLKEKLELEEEyllYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   467 MDEVQDTF---RDDEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSFNAEL-----SNKIKKLEEELRF 538
Cdd:pfam02463  246 LRDEQEEIessKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERrkvddEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   539 SNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDL----KDQLKF 614
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEelelKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   615 AEEELQRLRDRERKRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSNVAVTQTDF----EVPDRNVSIE 690
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEdllkETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   691 RETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVllsgaGRKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLEL 770
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGV-----GGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   771 NEQEASILRLKVEDLEKENAESKKyvRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTV 850
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLI--PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   851 DSLKNQLSKLDTLETENDKLAKENKRllalrkaSEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKR 930
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEV-------KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   931 VNDLTpkshlkkwvEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSEL 1010
Cdd:pfam02463  712 LKKLK---------LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1011 EQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE 1090
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1091 LLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKryEDLNNHWEKLSEETILMRAQLTTEK 1170
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK--ENEIEERIKEEAEILLKYEEEPEEL 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1171 QSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQ-AKALKTVNGNGAEYERTVLKNK---LAEKEHEYERLR 1246
Cdd:pfam02463  941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEfEEKEERYNKDELEKERLEEEKKkliRAIIEETCQRLK 1020

                          890       900       910
                   ....*....|....*....|....*....|..
gi 161076750  1247 RENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQ 1278
Cdd:pfam02463 1021 EFLELFVSINKGWNKVFFYLELGGSAELRLED 1052
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1001-1437 1.11e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 1.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1001 NGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKR-EKEK----------------- 1062
Cdd:TIGR04523   71 NNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKlEKQKkenkknidkflteikkk 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1063 ---LSSLEKDMEKQAKEKEKLEAKISQLDAELLSAK---KSAEKSKSSLEKEIKDLKTKASKSDS--KQVQDLKKQVEEV 1134
Cdd:TIGR04523  151 ekeLEKLNNKYNDLKKQKEELENELNLLEKEKLNIQkniDKIKNKLLKLELLLSNLKKKIQKNKSleSQISELKKQNNQL 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1135 QASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSL---QAELNASKQKI--------------------------- 1184
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLsekQKELEQNNKKIkelekqlnqlkseisdlnnqkeqdwnk 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1185 ---AEMDTIRIERTDMARKLSEAQKRIADL--QAKALKTvNGNGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQL 1259
Cdd:TIGR04523  311 elkSELKNQEKKLEEIQNQISQNNKIISQLneQISQLKK-ELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1260 RKDNDDLNGKLSDYNRIEQaqsslnghgaRREAEIRELKEQLQSTELQMKSEVATvRLRYEQQVKNLSGELTSMQRQCER 1339
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQ----------QKDEQIKKLQQEKELLEKEIERLKET-IIKNNSEIKDLTNQDSVKELIIKN 458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1340 FKKDRDAFKQMLEVAQKKIG----DLKANNTGRQSRGSMHSSDDDDKSKiayLEQQIGHLEDQLVESRlesSKIKtELVS 1415
Cdd:TIGR04523  459 LDNTRESLETQLKVLSRSINkikqNLEQKQKELKSKEKELKKLNEEKKE---LEEKVKDLTKKISSLK---EKIE-KLES 531

                          490       500
                   ....*....|....*....|..
gi 161076750  1416 ERSANEIKISEMQSKLNEFEEE 1437
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFE 553
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 769-1494 1.12e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.52  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   769 ELNEQEASILRLKVEDLEKENAESKKY------VRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRT 842
Cdd:pfam15921   99 ELHEKQKFYLRQSVIDLQTKLQEMQMErdamadIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKM 178

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   843 LTEKEQTVDSLKnqlSKLDTLETENDKLAKENKRLLALRKASektgevdqkMKESLAQAQRERDELTARLKRMQLEAEDK 922
Cdd:pfam15921  179 MLSHEGVLQEIR---SILVDFEEASGKKIYEHDSMSTMHFRS---------LGSAISKILRELDTEISYLKGRIFPVEDQ 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   923 LPPRTAKRVNDLtpKSHLKKWVEELEDEISEMRVMLS------SSGTDQLKALQSAKGALEEDLRKckqklslaeGDVQR 996
Cdd:pfam15921  247 LEALKSESQNKI--ELLLQQHQDRIEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARN---------QNSMY 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   997 LKLLNGSSSKVSELEQKLKrgdeEAKKL-NSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAK 1075
Cdd:pfam15921  316 MRQLSDLESTVSQLRSELR----EAKRMyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREK 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1076 EKEkLEakiSQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKqvqdLKKQVEEVQASLSAEQKRYEDLNNHWEKL 1155
Cdd:pfam15921  392 ELS-LE---KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAL----LKAMKSECQGQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1156 SEETilmrAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRI-------------ADLQAKALKTVNGN 1222
Cdd:pfam15921  464 SSLT----AQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIeatnaeitklrsrVDLKLQELQHLKNE 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1223 G-----AEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQlrkdnddlNGKLSDYNRIEQAQSSLNGHGAR-------- 1289
Cdd:pfam15921  540 GdhlrnVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ--------HGRTAGAMQVEKAQLEKEINDRRlelqefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1290 ----REAEIRELKEQLQSTELQMKSEV--ATVRLRYEQ-----------QVKNLSGELTSMQRQCERFKKD-RDAFKQML 1351
Cdd:pfam15921  612 lkdkKDAKIRELEARVSDLELEKVKLVnaGSERLRAVKdikqerdqllnEVKTSRNELNSLSEDYEVLKRNfRNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1352 EVAQKKIGDLK-ANNTGRQSRGSMHSSDDDDkskiayleqqiGHledqlvesrleSSKIKTELVSERSANEIKISEMQSK 1430
Cdd:pfam15921  692 TTTNKLKMQLKsAQSELEQTRNTLKSMEGSD-----------GH-----------AMKVAMGMQKQITAKRGQIDALQSK 749

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 161076750  1431 LnEFEEERVIGSGSTKlpgmktklelswQKEREDQQRLLQETSTLARDLRQTLFEVERERDKER 1494
Cdd:pfam15921  750 I-QFLEEAMTNANKEK------------HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQER 800
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 898-1186 1.58e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  898 LAQAQRERDELTARLKRMQLEAEDklpprtakrvndltpkshLKKWVEELEDEISEMRvmlsssgtDQLKALQSAKGALE 977
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEE------------------LEAELAELEAELEELR--------LELEELELELEEAQ 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  978 EDLRKCKQKLSLAEGDVQRLKLLNgssskvSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSK 1057
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERR------RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1058 REKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQAS 1137
Cdd:COG1196   362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 161076750 1138 LSAEQKRYEDLNNhwEKLSEETILMRAQLTTEKQSLQAELNASKQKIAE 1186
Cdd:COG1196   442 EALEEAAEEEAEL--EEEEEALLELLAELLEEAALLEAALAELLEELAE 488
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 348-1150 1.77e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAEREKSDILLRRLASM----DTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRM 423
Cdd:pfam02463  213 YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDeqeeIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   424 KELENKGSE--------SELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTF-RDDEVKAKTSLQKDLEKATK 494
Cdd:pfam02463  293 KEEEELKSEllklerrkVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKReAEEEEEEELEKLQEKLEQLE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   495 NCRILSFKLKKSDRKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGV---LGKST 571
Cdd:pfam02463  373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGkltEEKEE 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   572 SADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKRVRFSCGTQTEVPLEVVAFPRGT 651
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLG 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   652 qTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPfAGLFPPSSSSRVGQSGSLLFPSAISHVLLSGAG 731
Cdd:pfam02463  533 -DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA-RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   732 RKLSPTPHPHR-----LAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLE--KENAESKKYVRELQAKLR 804
Cdd:pfam02463  611 ATLEADEDDKRakvveGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSEltKELLEIQELQEKAESELA 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   805 QDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENdkLAKENKRLLALRKAS 884
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEE--KSRLKKEEKEEEKSE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   885 EKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTD 964
Cdd:pfam02463  769 LSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   965 QLKALQSAKGALEEDL-RKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDlEDKVKKQEAQLK 1043
Cdd:pfam02463  849 EKLAEEELERLEEEITkEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK-ENEIEERIKEEA 927

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1044 LGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAE--LLSAKKSAEKSKSSLEKEIKDLKTKASKSDS 1121
Cdd:pfam02463  928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKvnLMAIEEFEEKEERYNKDELEKERLEEEKKKL 1007

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 161076750  1122 KQVQD-------------------LKKQVEEVQASLSAEQKRYEDLNN 1150
Cdd:pfam02463 1008 IRAIIeetcqrlkeflelfvsinkGWNKVFFYLELGGSAELRLEDPDD 1055
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 779-1440 2.58e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 59.29  E-value: 2.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   779 RLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKtLNEELVQLRRTLTEKEQTVDSLKNQLS 858
Cdd:TIGR00606  397 TLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEI-LEKKQEELKFVIKELQQLEGSSDRILE 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   859 KLDTLETENDKLAK-ENKRLLALRKASEKTGEVDQ----KMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVN- 932
Cdd:TIGR00606  476 LDQELRKAERELSKaEKNSLTETLKKEVKSLQNEKadldRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIk 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   933 ------------DLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEgdvqrlKLL 1000
Cdd:TIGR00606  556 srhsdeltsllgYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYED------KLF 629

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1001 NGSSSKvsELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLklgetSKSTWESQS---------KREKE------KLSS 1065
Cdd:TIGR00606  630 DVCGSQ--DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFI-----TQLTDENQSccpvcqrvfQTEAElqefisDLQS 702

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1066 LEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKaSKSDSKQVQDLKKQVEEVQASLS---AEQ 1142
Cdd:TIGR00606  703 KLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNK-LQKVNRDIQRLKNDIEEQETLLGtimPEE 781

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1143 KRYEDLNNH---WEKLSEETILMR---AQLTTEKQSLQ-----AELNASKQ-KIAEMDTIRIERTDMARKLSEAQKRIAD 1210
Cdd:TIGR00606  782 ESAKVCLTDvtiMERFQMELKDVErkiAQQAAKLQGSDldrtvQQVNQEKQeKQHELDTVVSKIELNRKLIQDQQEQIQH 861

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1211 LQAKAlktvngNGAEYERTVLKNKLAEK----EHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGH 1286
Cdd:TIGR00606  862 LKSKT------NELKSEKLQIGTNLQRRqqfeEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETS 935

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1287 GARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNT 1366
Cdd:TIGR00606  936 NKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQER 1015

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161076750  1367 GRQSRGSMHSSDDDDKSKIAYLEQQIGHL-EDQLVESRLESSKIKTELVSERSANEIKISEMQsklnEFEEERVI 1440
Cdd:TIGR00606 1016 WLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQK----GYEKEIKH 1086
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 742-1187 4.68e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 4.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  742 RLAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKL--RQDSSNGSKSSLLSLG 819
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELeeLAEELLEALRAAAELA 399

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  820 TSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKL-DTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESL 898
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEeEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  899 AQAQRERDELTAR---LKRMQLEAEDKLPPRTAKRVNDLTPKSH-----LKKWVEELEDEISEmrVMLSSSGTDQLKALQ 970
Cdd:COG1196   480 AELLEELAEAAARlllLLEAEADYEGFLEGVKAALLLAGLRGLAgavavLIGVEAAYEAALEA--ALAAALQNIVVEDDE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  971 SAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKS 1050
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1051 TWESQSKREKEKL-----SSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQ 1125
Cdd:COG1196   638 RAVTLAGRLREVTlegegGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161076750 1126 DLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEM 1187
Cdd:COG1196   718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 999-1530 9.91e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 9.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   999 LLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEA-------QLKLGETSKSTWESQSKREKEKLSSLEKDME 1071
Cdd:TIGR04523   27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEkinnsnnKIKILEQQIKDLNDKLKKNKDKINKLNSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1072 KQAKE-------KEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDskqvqDLKKQVEEVQASLSAEQKR 1144
Cdd:TIGR04523  107 KINSEikndkeqKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYN-----DLKKQKEELENELNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1145 YEDLNN-----HWEKLSEETILMRAQLTTEKQ-SLQAELNASKQKIAEMDTIRIERT----DMARKLSEAQKRIADL--- 1211
Cdd:TIGR04523  182 KLNIQKnidkiKNKLLKLELLLSNLKKKIQKNkSLESQISELKKQNNQLKDNIEKKQqeinEKTTEISNTQTQLNQLkde 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1212 QAKALKTVNGNGAEYERT-----VLKNKLAEKEHEYERLRRENEMNI--DLVFQLRKDNDDLNGKLSDYNRIEQAQSSLN 1284
Cdd:TIGR04523  262 QNKIKKQLSEKQKELEQNnkkikELEKQLNQLKSEISDLNNQKEQDWnkELKSELKNQEKKLEEIQNQISQNNKIISQLN 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1285 GHGARREAEIRELKEQLQSTELQMKSEVATVRL------RYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQ--- 1355
Cdd:TIGR04523  342 EQISQLKKELTNSESENSEKQRELEEKQNEIEKlkkenqSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQqek 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1356 ----KKIGDLKANNTGRQSR-GSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELvsERSANEIKISEmqSK 1430
Cdd:TIGR04523  422 elleKEIERLKETIIKNNSEiKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNL--EQKQKELKSKE--KE 497

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1431 LNEFEEERVIGSGSTK-LPGMKTKLELSWQKEREDQQRLLQETSTLARDLRQTLFEVERER-DKERLESKRKLDQIKRAT 1508
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKdLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlEKEIDEKNKEIEELKQTQ 577

                          570       580
                   ....*....|....*....|....*
gi 161076750  1509 EE---EMEEGRKKIAELQCDLLELR 1530
Cdd:TIGR04523  578 KSlkkKQEEKQELIDQKEKEKKDLI 602
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
964-1528 1.26e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 1.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  964 DQLKALQSAKGALEEDLRKCKQKLslaEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLK 1043
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKEL---EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKR 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1044 LGETSKSTWESQSKREKEKLSSLEKDME--KQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASK--S 1119
Cdd:PRK03918  256 KLEEKIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEleE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1120 DSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEmdtIRIERTDMAR 1199
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEE---IEEEISKITA 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1200 KLSEAQKRIADLQA--KALKTVNGN----GAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDY 1273
Cdd:PRK03918  413 RIGELKKEIKELKKaiEELKKAKGKcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKE 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1274 NRIEQAQSSLNghgarreaEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKkdrdAFKQMLEV 1353
Cdd:PRK03918  493 SELIKLKELAE--------QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE----ELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1354 AQKKIGDL--KANNTGRQSRGSMHSSDDDDKSKIAYLEQQIG-HLEDQLVESRLESskIKTELVSERSANEIKISEMQSK 1430
Cdd:PRK03918  561 LEKKLDELeeELAELLKELEELGFESVEELEERLKELEPFYNeYLELKDAEKELER--EEKELKKLEEELDKAFEELAET 638

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1431 LNEFEEervigsgstklpgMKTKLElswqkeredqqrllqetstlarDLRQTLFEVERERDKERLESKRKLDQIKRATEE 1510
Cdd:PRK03918  639 EKRLEE-------------LRKELE----------------------ELEKKYSEEEYEELREEYLELSRELAGLRAELE 683

                         570
                  ....*....|....*...
gi 161076750 1511 EMEEGRKKIAELQCDLLE 1528
Cdd:PRK03918  684 ELEKRREEIKKTLEKLKE 701
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
751-1202 2.01e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.20  E-value: 2.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  751 RDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKL--RQDSSNGSKSSLLSLGTSSSAAEKK 828
Cdd:PRK02224  236 RDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLeeLEEERDDLLAEAGLDDADAEAVEAR 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  829 VKTLNEELVQLRRTLTEKEQTVDSLKNQLSKL----DTLETENDKLAKENKRL--------LALRKASEKTGEVDQKM-- 894
Cdd:PRK02224  316 REELEDRDEELRDRLEECRVAAQAHNEEAESLredaDDLEERAEELREEAAELeseleearEAVEDRREEIEELEEEIee 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  895 -KESLAQAQRERDELTARLKRMQLEAEdklppRTAKRVNDLTPKshlkkwVEELEDEISEMRVMLS-------------S 960
Cdd:PRK02224  396 lRERFGDAPVDLGNAEDFLEELREERD-----ELREREAELEAT------LRTARERVEEAEALLEagkcpecgqpvegS 464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  961 SGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDE---------EAKKLnsKLKDL 1031
Cdd:PRK02224  465 PHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEEliaerretiEEKRE--RAEEL 542

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1032 EDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEaKISQLDAELLSAKKSAEKSKSSLEK--EI 1109
Cdd:PRK02224  543 RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREAlaEL 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1110 KDLKTKASKSDSKQVQDLKKQVEEvqASLSAEQKRYEDLNNHWEKLSEETilmrAQLTTEKQSLQAELNASKQKIAEMDT 1189
Cdd:PRK02224  622 NDERRERLAEKRERKRELEAEFDE--ARIEEAREDKERAEEYLEQVEEKL----DELREERDDLQAEIGAVENELEELEE 695

                         490
                  ....*....|...
gi 161076750 1190 IRIERTDMARKLS 1202
Cdd:PRK02224  696 LRERREALENRVE 708
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 893-1529 3.38e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   893 KMKESLAQAQRERDELTARLKRMQLEAEDKLpprtakrvndltpkSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSA 972
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKAL--------------EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   973 KGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQ-KLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKST 1051
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEeELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1052 WESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKAS--------KSDSKQ 1123
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKlkeeelelKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1124 VQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSE 1203
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1204 AQKRIAD-------------------------------------------LQAKALKTVNGNGAEYERTVLKNKLAEKEH 1240
Cdd:pfam02463  486 LELLLSRqkleersqkeskarsglkvllalikdgvggriisahgrlgdlgVAVENYKVAISTAVIVEVSATADEVEERQK 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1241 EYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEI---RELKEQLQSTELQMKSEVATVRL 1317
Cdd:pfam02463  566 LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDkraKVVEGILKDTELTKLKESAKAKE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1318 RYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRgsmhssddddksKIAYLEQQIGHLED 1397
Cdd:pfam02463  646 SGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQL------------EIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1398 QLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVIGSGSTKLpgmKTKLELSWQKEREDQQRLLQETSTLAR 1477
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE---EEKSELSLKEKELAEEREKTEKLKVEE 790

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 161076750  1478 DLRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCDLLEL 1529
Cdd:pfam02463  791 EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 348-1088 3.67e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 3.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEK------AEREKSDILLRRLASMDTASNRT-----AASEALN-LQQKLNEMKEQLDRVTED 415
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETrdelkDYREKLEkLKREINELKRELDRLQEE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   416 KRKLNLRMKELENKGseselrrklqaaeqiceelmeenQSAKKEILNLQAEMDEVQDTFRDDEVKAKTsLQKDLEKATKN 495
Cdd:TIGR02169  415 LQRLSEELADLNAAI-----------------------AGIEAKINELEEEKEDKALEIKKQEWKLEQ-LAADLSKYEQE 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   496 CRILSFKLKKSDRKIETLEQErqssfnaelsnkIKKLEEELRFSNELTRKLQAEAEELRNPGKKkapMLGVLGKSTSADA 575
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRE------------LAEAEAQARASEERVRGGRAVEEVLKASIQG---VHGTVAQLGSVGE 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   576 KFTRESLTRGGSQedpqhlqrelQDSIERETDLkdqlkFAEEELQRLRDRERKRVRFscgtqteVPLEVVAFPRgtqtva 655
Cdd:TIGR02169  536 RYATAIEVAAGNR----------LNNVVVEDDA-----VAKEAIELLKRRKAGRATF-------LPLNKMRDER------ 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   656 tvqSDMSTSVENLVTsNVAVTQTDFEVPDRNV--SIERET--MSSPFAGLFPPSSSSRVGQSGSLLFPSAishVLLSGAG 731
Cdd:TIGR02169  588 ---RDLSILSEDGVI-GFAVDLVEFDPKYEPAfkYVFGDTlvVEDIEAARRLMGKYRMVTLEGELFEKSG---AMTGGSR 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   732 RKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGS 811
Cdd:TIGR02169  661 APRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   812 KSSL--LSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQL--SKLDTLETENDKLAKENKRLlalrkaSEKT 887
Cdd:TIGR02169  741 ELEEdlSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshSRIPEIQAELSKLEEEVSRI------EARL 814

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   888 GEVDQKMKESLAQAQRERDELtARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRvmlsssgtDQLK 967
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE--------SRLG 885

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   968 ALQSAKGALEEDLRKCKQKLSLAEGDVQRLKL--------LNGSSSKVSELEQKLKRGDEEAKKLNSkLKDLEDKVKKQE 1039
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKrlselkakLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVE 964

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 161076750  1040 AQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLD 1088
Cdd:TIGR02169  965 EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
834-1371 7.09e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 7.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  834 EELVQLRRTLTEKEQtvdslKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLK 913
Cdd:PRK02224  187 GSLDQLKAQIEEKEE-----KDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIE 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  914 --RMQLEAEDKLPPRTAKRVNDLtpkshlKKWVEELEDEISEMRVML------SSSGTDQLKALQSAKGALEEDLRKCKQ 985
Cdd:PRK02224  262 dlRETIAETEREREELAEEVRDL------RERLEELEEERDDLLAEAglddadAEAVEARREELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  986 KLSLAEGDVQRLKllngssskvseleQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQ--SKREK--- 1060
Cdd:PRK02224  336 AAQAHNEEAESLR-------------EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEieELRERfgd 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1061 --EKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLE--------KEIKDlktkasKSDSKQVQDLKKQ 1130
Cdd:PRK02224  403 apVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgQPVEG------SPHVETIEEDRER 476

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1131 VEEVQASLSAEQKRYEDLNNHWEKLSEetilmRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDmarKLSEAQKRIAD 1210
Cdd:PRK02224  477 VEELEAELEDLEEEVEEVEERLERAED-----LVEAEDRIERLEERREDLEELIAERRETIEEKRE---RAEELRERAAE 548

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1211 LQAKAlktvngngaeyertvlknklAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARR 1290
Cdd:PRK02224  549 LEAEA--------------------EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEI 608

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1291 EaEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGEltsmqrQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQS 1370
Cdd:PRK02224  609 E-RLREKREALAELNDERRERLAEKRERKRELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQA 681


                  .
gi 161076750 1371 R 1371
Cdd:PRK02224  682 E 682
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
954-1214 7.58e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.25  E-value: 7.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  954 MRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSkvseleqklkrGDEEAKKLNSKLKDLED 1033
Cdd:COG3206   158 AEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD-----------LSEEAKLLLQQLSELES 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1034 KVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDmekqakekekleAKISQLDAELlsakksaekskSSLEKEIKDLK 1113
Cdd:COG3206   227 QLAEARAELAEAEARLAALRAQLGSGPDALPELLQS------------PVIQQLRAQL-----------AELEAELAELS 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1114 TKASkSDSKQVQDLKKQVEEVQASLSAEQKRyedlnnhwekLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIE 1193
Cdd:COG3206   284 ARYT-PNHPDVIALRAQIAALRAQLQQEAQR----------ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                         250       260
                  ....*....|....*....|.
gi 161076750 1194 RTDMARKLSEAQKRIADLQAK 1214
Cdd:COG3206   353 LRRLEREVEVARELYESLLQR 373
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
769-1246 8.00e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 8.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  769 ELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQ 848
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  849 TVDSLKNQLSKLDTLETENDKLAKENKRL-----LALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDKl 923
Cdd:COG4717   147 RLEELEERLEELRELEEELEELEAELAELqeeleELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL- 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  924 pprtAKRVNDLTPkshlKKWVEELEDEISEMRVMLSSSGTdqLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGS 1003
Cdd:COG4717   226 ----EEELEQLEN----ELEAAALEERLKEARLLLLIAAA--LLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1004 SSKVSELEQKLKRGDEEAKKLNSKlkdledKVKKQEAQLKLGETskstwesqskREKEKLSSLEKDMEKQAKEKEKLEAK 1083
Cdd:COG4717   296 EKASLGKEAEELQALPALEELEEE------ELEELLAALGLPPD----------LSPEELLELLDRIEELQELLREAEEL 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1084 ISQLDAEllsakksaeksksSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQaslsAEQKRYEDLNnhwEKLSEETILMR 1163
Cdd:COG4717   360 EEELQLE-------------ELEQEIAALLAEAGVEDEEELRAALEQAEEYQ----ELKEELEELE---EQLEELLGELE 419

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1164 AQL-TTEKQSLQAELNASKQKIAEMDTiriERTDMARKLSEAQKRIADLQAKALKTVngngAEYERTVLKNKLAEKEHEY 1242
Cdd:COG4717   420 ELLeALDEEELEEELEELEEELEELEE---ELEELREELAELEAELEQLEEDGELAE----LLQELEELKAELRELAEEW 492


                  ....
gi 161076750 1243 ERLR 1246
Cdd:COG4717   493 AALK 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1002-1217 8.09e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 8.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1002 GSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKlgetsksTWESQSKREKEKLSSLEKDMEKQAKEKEKLE 1081
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-------ALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1082 AKISQLDAELLSAKKSAEKSKSSLEK--EIKDLKTKASKSDSKQ-------VQDLKKQVEEVQASLSAEQKRYEDLNNHW 1152
Cdd:COG4942    90 KEIAELRAELEAQKEELAELLRALYRlgRQPPLALLLSPEDFLDavrrlqyLKYLAPARREQAEELRADLAELAALRAEL 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161076750 1153 EKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALK 1217
Cdd:COG4942   170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1123-1433 1.10e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 53.36  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1123 QVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLS 1202
Cdd:pfam07888   35 RLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELS 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1203 EaqKRIADLQAKALKTVNGNGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKL----SDYNRIEQ 1278
Cdd:pfam07888  115 E--EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLqqteEELRSLSK 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1279 AQSSLNGHGARREAEIRELKEQLQSTEL-------------QMKSEVATVRLRY---EQQVKNLSGELTSMQRQceRFKK 1342
Cdd:pfam07888  193 EFQELRNSLAQRDTQVLQLQDTITTLTQklttahrkeaeneALLEELRSLQERLnasERKVEGLGEELSSMAAQ--RDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1343 DRDAFKQMLEVAQKKIGDLKANNTGR-------QSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVS 1415
Cdd:pfam07888  271 QAELHQARLQAAQLTLQLADASLALRegrarwaQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGR 350

                          330
                   ....*....|....*...
gi 161076750  1416 ERSANEIKISEMQSKLNE 1433
Cdd:pfam07888  351 EKDCNRVQLSESRRELQE 368
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 396-1175 1.15e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   396 LNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESElrRKLQAAEQICEELMEENQSA----KKEILNLQAEMDEVQ 471
Cdd:pfam15921  113 IDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV--HELEAAKCLKEDMLEDSNTQieqlRKMMLSHEGVLQEIR 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   472 DTFRDDEVKAKTSLQKDLEKATKNCRILSFKLKK-----------------------------SDRKIETLEQERQ---- 518
Cdd:pfam15921  191 SILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKilreldteisylkgrifpvedqlealkseSQNKIELLLQQHQdrie 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   519 ---SSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESltrggsqedpqhlQ 595
Cdd:pfam15921  271 qliSEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA-------------K 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   596 RELQDSIEretDLKDQLKFAEEELQRLRDrERKRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSN-VA 674
Cdd:pfam15921  338 RMYEDKIE---ELEKQLVLANSELTEART-ERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNsIT 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   675 VTQTDFEVPDRNVSIER-----ETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVLlsgagrklsptphphrlapevha 749
Cdd:pfam15921  414 IDHLRRELDDRNMEVQRleallKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQL----------------------- 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   750 drdegisdeddpaelrillelnEQEASILRLKVEDLEKEN---AESKKYVRELQAKLRQDssngskssllslgtsssaaE 826
Cdd:pfam15921  471 ----------------------ESTKEMLRKVVEELTAKKmtlESSERTVSDLTASLQEK-------------------E 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   827 KKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKL----AKENKRLLALRKASEKTGEVDQKMKESLAQAQ 902
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQ 589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   903 RERDELTARL--KRMQLEAEDKLPPRTAKRVNDLTPKshlkkwVEELEDEisemRVMLSSSGTDQLKALQSAK---GALE 977
Cdd:pfam15921  590 VEKAQLEKEIndRRLELQEFKILKDKKDAKIRELEAR------VSDLELE----KVKLVNAGSERLRAVKDIKqerDQLL 659

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   978 EDLRKCKQKLSLAEGDVQRLKllNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEA------QLKLGETSKST 1051
Cdd:pfam15921  660 NEVKTSRNELNSLSEDYEVLK--RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMGMQKQIT 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1052 WE-SQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakKSAEKSKSSLEKEIKDLKTkasksdskQVQDLKKQ 1130
Cdd:pfam15921  738 AKrGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQEL----STVATEKNKMAGELEVLRS--------QERRLKEK 805

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 161076750  1131 VEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQA 1175
Cdd:pfam15921  806 VANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
46 PHA02562
endonuclease subunit; Provisional
 1022-1211 1.42e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 53.09  E-value: 1.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1022 KKLNSKLKDLEDKVKKQEAQLKlgeTSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKS 1101
Cdd:PHA02562  177 RELNQQIQTLDMKIDHIQQQIK---TYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1102 KSSLEKeIKDLKTKAsKSDSKQVQDLKK--------------------QVEEVQASLSAEQKRYEDLNNHWEKLSE---- 1157
Cdd:PHA02562  254 SAALNK-LNTAAAKI-KSKIEQFQKVIKmyekggvcptctqqisegpdRITKIKDKLKELQHSLEKLDTAIDELEEimde 331

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1158 -----ETIL-MRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADL 1211
Cdd:PHA02562  332 fneqsKKLLeLKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKI 391
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
826-1092 1.74e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  826 EKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRkaSEKTGEVDQKMKESLAQAQRER 905
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELE--YLRAALRLWFAQRRLELLEAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  906 DELTARLKRMQLEAEDklpprtakrvndltpkshLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQ 985
Cdd:COG4913   298 EELRAELARLEAELER------------------LEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERER 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  986 KLSLAEGDVQRLKLLNGSSSKvsELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLklgetskstweSQSKREKEKLSs 1065
Cdd:COG4913   360 RRARLEALLAALGLPLPASAE--EFAALRAEAAALLEALEEELEALEEALAEAEAAL-----------RDLRRELRELE- 425

                         250       260
                  ....*....|....*....|....*..
gi 161076750 1066 lekdmekqaKEKEKLEAKISQLDAELL 1092
Cdd:COG4913   426 ---------AEIASLERRKSNIPARLL 443
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 422-1323 2.06e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 2.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   422 RMKELENKGSESELRRKLQAAEqicEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSF 501
Cdd:pfam02463  154 RRLEIEEEAAGSRLKRKKKEAL---KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLD 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   502 KLKKSDRKIETLEQERQSsfNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKapmlgvlgkstsadakftres 581
Cdd:pfam02463  231 YLKLNEERIDLLQELLRD--EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEE--------------------- 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   582 ltRGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKRVRFScgTQTEVPLEVVAFPRGTQTVATVQSDM 661
Cdd:pfam02463  288 --LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI--EELEKELKELEIKREAEEEEEEELEK 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   662 STSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVLLSGAGRKLSPTphph 741
Cdd:pfam02463  364 LQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI---- 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   742 rlapevhaDRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTS 821
Cdd:pfam02463  440 --------ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKV 511

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   822 SSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKAsektgevdqkmKESLAQA 901
Cdd:pfam02463  512 LLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTEL-----------PLGARKL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   902 QRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLR 981
Cdd:pfam02463  581 RLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAE 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   982 KCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKstweSQSKREKE 1061
Cdd:pfam02463  661 KSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ----EAQDKINE 736

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1062 KLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAE 1141
Cdd:pfam02463  737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAEL 816

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1142 QKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIErtdmaRKLSEAQKRIADLQAKALKTVNG 1221
Cdd:pfam02463  817 LEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL-----LQELLLKEEELEEQKLKDELESK 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1222 NGAEY-ERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNdDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQ 1300
Cdd:pfam02463  892 EEKEKeEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE-EEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970

                          890       900
                   ....*....|....*....|....
gi 161076750  1301 LQST-ELQMKSEVATVRLRYEQQV 1323
Cdd:pfam02463  971 ELGKvNLMAIEEFEEKEERYNKDE 994
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 769-1519 2.29e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.13  E-value: 2.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   769 ELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTL-TEKE 847
Cdd:TIGR01612  975 KINELDKAFKDASLNDYEAKNNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIhTSIY 1054

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   848 QTVDSLKNQLSK-LDTLETEndKLAKENKRLLALRKASEK-----------------TGEVDqKMKESLAQAQRERDELT 909
Cdd:TIGR01612 1055 NIIDEIEKEIGKnIELLNKE--ILEEAEINITNFNEIKEKlkhynfddfgkeenikyADEIN-KIKDDIKNLDQKIDHHI 1131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   910 ARLKRMQLEAEDKLPPRTAK--RVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGT--DQLKALQSAKGALEEDlrkckq 985
Cdd:TIGR01612 1132 KALEEIKKKSENYIDEIKAQinDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNiyDEIKKLLNEIAEIEKD------ 1205

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   986 KLSLAEgdVQRLKLLNGSSSKVSELEQKlkrgDEEAKKLNSKLKDLE------DKVKKQEAQLKlgetSKSTWESQSKRE 1059
Cdd:TIGR01612 1206 KTSLEE--VKGINLSYGKNLGKLFLEKI----DEEKKKSEHMIKAMEayiedlDEIKEKSPEIE----NEMGIEMDIKAE 1275

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1060 KEKLSSLEKDMEKQAKEKEKLEAKISQLDaellsakksaeksksslEKEIKDLKTKASKSDskqVQDLKKqveEVQASLS 1139
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENISDIR-----------------EKSLKIIEDFSEESD---INDIKK---ELQKNLL 1332

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1140 AEQKRYEDLNNHwekLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQ---AKAL 1216
Cdd:TIGR01612 1333 DAQKHNSDINLY---LNEIANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEeckSKIE 1409

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1217 KTVNG---NGAEYERTVLKNKLAEKE---HEYERLRRENEMNIDLVFQ-----------LRKDNDDLNGKLSDYNRIEQA 1279
Cdd:TIGR01612 1410 STLDDkdiDECIKKIKELKNHILSEEsniDTYFKNADENNENVLLLFKniemadnksqhILKIKKDNATNDHDFNINELK 1489

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1280 QSSLNGHGARREAEiRELKEQLQSTEL--QMKSEVATVRLRY-EQQVKNlsgELTSMQRQCERFKKD-RDAFKQML---E 1352
Cdd:TIGR01612 1490 EHIDKSKGCKDEAD-KNAKAIEKNKELfeQYKKDVTELLNKYsALAIKN---KFAKTKKDSEIIIKEiKDAHKKFIleaE 1565

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1353 VAQKKIGDLKANNTGRQSRGSmhssdDDDKSKIAYLEQQIG--HLEDQLvesrLESSKIKTEL---VSERSANEIKISEM 1427
Cdd:TIGR01612 1566 KSEQKIKEIKKEKFRIEDDAA-----KNDKSNKAAIDIQLSleNFENKF----LKISDIKKKIndcLKETESIEKKISSF 1636

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1428 QSKLNEFEeervIGSGSTKLPGMKTKLE-LSWQKER-EDQQRLLQETSTlarDLRQTLFEVERERDKERLESKRKLDQIK 1505
Cdd:TIGR01612 1637 SIDSQDTE----LKENGDNLNSLQEFLEsLKDQKKNiEDKKKELDELDS---EIEKIEIDVDQHKKNYEIGIIEKIKEIA 1709

                          810
                   ....*....|....
gi 161076750  1506 RATEEEMEEGRKKI 1519
Cdd:TIGR01612 1710 IANKEEIESIKELI 1723
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1651-1895 2.98e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.48  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1651 DEQERSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLS-------RNSSNNGS--LIRKSLSLDHSIQRDQNIW 1721
Cdd:PHA03307  133 DLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLsspeetaRAPSSPPAepPPSTPPAAASPRPPRRSSP 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1722 RQDDGSVSSMQSIDSELGGLVRDSSLDSRLDSRLSGGSTQSDIPRG-------PRKKKKGIMGKLRSLTKSSRNSESeiS 1794
Cdd:PHA03307  213 ISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPrpapitlPTRIWEASGWNGPSSRPGPASSSS--S 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1795 IQGSDSDISVASDmRSSKKDLRGRLSGMFKRSGSASRSESMER-AGSDQRPVAVTVVGHPDGPQPREPPPANslTPRPIR 1873
Cdd:PHA03307  291 PRERSPSPSPSSP-GSGPAPSSPRASSSSSSSRESSSSSTSSSsESSRGAAVSPGPSPSRSPSPSRPPPPAD--PSSPRK 367

                         250       260
                  ....*....|....*....|....*
gi 161076750 1874 SIPKPPSAGAPTTPT---TRRRVAK 1895
Cdd:PHA03307  368 RPRPSRAPSSPAASAgrpTRRRARA 392
PRK01156 PRK01156
chromosome segregation protein; Provisional
 751-1230 3.32e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 52.21  E-value: 3.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  751 RDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKE-NAESKKY-----------------------VRELQAKLRQD 806
Cdd:PRK01156  189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEyNNAMDDYnnlksalnelssledmknryeseIKTAESDLSME 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  807 SSNGSKSSLLSLGTSSSAAEKKVKTLNE--ELVQLRRTLTEKEQTVDSLKNQLS-------KLDTLETENDKLAKENKRL 877
Cdd:PRK01156  269 LEKNNYYKELEERHMKIINDPVYKNRNYinDYFKYKNDIENKKQILSNIDAEINkyhaiikKLSVLQKDYNDYIKKKSRY 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  878 LALRK--ASEKTGEVD-QKMKESLAQAQRERDELTARLKRMQLEAEDKLpprtakRVNDLTPkshlkkwvEELEDEISEM 954
Cdd:PRK01156  349 DDLNNqiLELEGYEMDyNSYLKSIESLKKKIEEYSKNIERMSAFISEIL------KIQEIDP--------DAIKKELNEI 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  955 RVMLSSSGTDqLKALQSAKGALEEDLRKCKQKLSLAEG------------DVQRLKLLNGSSSKVSELEQKLKRGDEEAK 1022
Cdd:PRK01156  415 NVKLQDISSK-VSSLNQRIRALRENLDELSRNMEMLNGqsvcpvcgttlgEEKSNHIINHYNEKKSRLEEKIREIEIEVK 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1023 KLNSKLKDLedkvKKQEAQLKLGETSKStwESQSKREKEKLSSLEKDMEKQAKEKEK------LEAKISQLDAELLSAKK 1096
Cdd:PRK01156  494 DIDEKIVDL----KKRKEYLESEEINKS--INEYNKIESARADLEDIKIKINELKDKhdkyeeIKNRYKSLKLEDLDSKR 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1097 SAEKSKSSLEKEIkDLKTKASKSD--SKQVQDLKKQVEEVQASLSaEQKRYEDlnNHWEKLSEETILMRAQ------LTT 1168
Cdd:PRK01156  568 TSWLNALAVISLI-DIETNRSRSNeiKKQLNDLESRLQEIEIGFP-DDKSYID--KSIREIENEANNLNNKyneiqeNKI 643

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161076750 1169 EKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQaKALKTVNGNGAEYERTV 1230
Cdd:PRK01156  644 LIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSR-KALDDAKANRARLESTI 704
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1005-1521 3.41e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 3.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1005 SKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKI 1084
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERI 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1085 SQLDAELLSAKKSAEKSKSSLEKE---IKDLKTKASKsDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLseetil 1161
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHeamISDLEERLKK-EEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAEL------ 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1162 mRAQLTTEKQSLQAELNASKQKIAemdtiriERTDMARKLSEAQKRIADLQAK-ALKTVNGNGAEYERTVLknklaekEH 1240
Cdd:pfam01576  235 -RAQLAKKEEELQAALARLEEETA-------QKNNALKKIRELEAQISELQEDlESERAARNKAEKQRRDL-------GE 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1241 EYERLRRENEMNIDLVfqlrkdnddlngklsdynrieQAQSSLNghgARREAEIRELKEQLQSTELQMKSEVATVRLRYE 1320
Cdd:pfam01576  300 ELEALKTELEDTLDTT---------------------AAQQELR---SKREQEVTELKKALEEETRSHEAQLQEMRQKHT 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1321 QQVKNLSGELtsmqRQCERFKKDRDAFKQMLEVAQKKI-GDLKANNTGRQsrgsmhssddDDKSKIAYLEQQIGHLEDQL 1399
Cdd:pfam01576  356 QALEELTEQL----EQAKRNKANLEKAKQALESENAELqAELRTLQQAKQ----------DSEHKRKKLEGQLQELQARL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1400 VesrlESSKIKTELVSERSANEIKISEMQSKLNEFEeervigSGSTKLPGMKTKLELSWQkereDQQRLLQETS----TL 1475
Cdd:pfam01576  422 S----ESERQRAELAEKLSKLQSELESVSSLLNEAE------GKNIKLSKDVSSLESQLQ----DTQELLQEETrqklNL 487

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 161076750  1476 ARDLRQTlfEVER----ERDKERLESKRKLDQIKRATEEEMEEGRKKIAE 1521
Cdd:pfam01576  488 STRLRQL--EDERnslqEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 929-1186 4.06e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.85  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  929 KRVNDLTPKSHLKKWVEELED----EISEMRVMLSS-SGTDQLKALQSAKGALEEdLRKCKQKLSLAEGDVQRLK----- 998
Cdd:PRK05771    7 KKVLIVTLKSYKDEVLEALHElgvvHIEDLKEELSNeRLRKLRSLLTKLSEALDK-LRSYLPKLNPLREEKKKVSvksle 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  999 -LLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKvkkqeaqlklgetskstwesqsKREKEKLSSLEKDMEKqAKEK 1077
Cdd:PRK05771   86 eLIKDVEEELEKIEKEIKELEEEISELENEIKELEQE----------------------IERLEPWGNFDLDLSL-LLGF 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1078 EKLEAKISQLDAELLSAKKSAEKSKSslEKEIKDLKTK------ASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNH 1151
Cdd:PRK05771  143 KYVSVFVGTVPEDKLEELKLESDVEN--VEYISTDKGYvyvvvvVLKELSDEVEEELKKLGFERLELEEEGTPSELIREI 220

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 161076750 1152 WEKLSEetilmraqLTTEKQSLQAELNASKQKIAE 1186
Cdd:PRK05771  221 KEELEE--------IEKERESLLEELKELAKKYLE 247
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1012-1240 4.24e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.85  E-value: 4.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1012 QKLKRGDEEAKKLNSKLKDLEDKVKKQEAqlKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAEL 1091
Cdd:PRK05771   46 RKLRSLLTKLSEALDKLRSYLPKLNPLRE--EKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEI 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1092 lsakksaekskSSLEK------EIKDLKTKAS--------KSDSKQVQDLKKQVEEVQASLSAEQKRY-------EDLNN 1150
Cdd:PRK05771  124 -----------ERLEPwgnfdlDLSLLLGFKYvsvfvgtvPEDKLEELKLESDVENVEYISTDKGYVYvvvvvlkELSDE 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1151 HWEKLSEetILMRAQLTTEKQSLQAELNASKQKIAEmdtIRIERTDMARKLSEAQKRIADLQakaLKTVNGNGAEYERTV 1230
Cdd:PRK05771  193 VEEELKK--LGFERLELEEEGTPSELIREIKEELEE---IEKERESLLEELKELAKKYLEEL---LALYEYLEIELERAE 264

                         250
                  ....*....|
gi 161076750 1231 LKNKLAEKEH 1240
Cdd:PRK05771  265 ALSKFLKTDK 274
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
827-1392 5.10e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  827 KKVKTLNE---ELVqlrrtLTEKE--QTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKtgevdqkmkesLAQA 901
Cdd:COG4913   204 KPIGDLDDfvrEYM-----LEEPDtfEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAER-----------YAAA 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  902 QRERDELTARLKRmqleaedkLPPRTAKRVNDLtpkshLKKWVEELEDEISEMRvmlsssgtDQLKALQSAKGALEEDLR 981
Cdd:COG4913   268 RERLAELEYLRAA--------LRLWFAQRRLEL-----LEAELEELRAELARLE--------AELERLEARLDALREELD 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  982 KCKQKLSLAEGDvqrlkllngsssKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLklgETSKSTWESQSKREKE 1061
Cdd:COG4913   327 ELEAQIRGNGGD------------RLEQLEREIERLERELEERERRRARLEALLAALGLPL---PASAEEFAALRAEAAA 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1062 KLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaekskSSLEKEIKDLKTKASKSDSKqVQDLKKQVEEvQASLSA- 1140
Cdd:COG4913   392 LLEALEEELEALEEALAEAEAALRDLRREL-----------RELEAEIASLERRKSNIPAR-LLALRDALAE-ALGLDEa 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1141 -------------EQKRYED-----LNN----------HWEKLSE--ETILMRAQLTTEK----QSLQAELNASKQKIAE 1186
Cdd:COG4913   459 elpfvgelievrpEEERWRGaiervLGGfaltllvppeHYAAALRwvNRLHLRGRLVYERvrtgLPDPERPRLDPDSLAG 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1187 MDTIR-----------------IERTDMARKLSEAQKRI-ADLQAKALKTV---NGNGAEYERTVL----KNKLAEKEHE 1241
Cdd:COG4913   539 KLDFKphpfrawleaelgrrfdYVCVDSPEELRRHPRAItRAGQVKGNGTRhekDDRRRIRSRYVLgfdnRAKLAALEAE 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1242 YERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGArREAEIRELKEQLQSTEL------QMKSEVATV 1315
Cdd:COG4913   619 LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAS-AEREIAELEAELERLDAssddlaALEEQLEEL 697

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1316 RLRY---EQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVA------------QKKIGDLKANNTGRQSRGSMHSSDDD 1380
Cdd:COG4913   698 EAELeelEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedlarlelrallEERFAAALGDAVERELRENLEERIDA 777

                         650
                  ....*....|..
gi 161076750 1381 DKSKIAYLEQQI 1392
Cdd:COG4913   778 LRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
399-625 5.14e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  399 QQKLNEMKEQLDRVTEDKRKLNLRMKELENKgsESELRRKLQAAEQICEELMEEN--QSAKKEILNLQAEMDEVQDTfrD 476
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAE--LDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDAS--S 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  477 DEVKAktsLQKDLEKAtkncrilsfklkksDRKIETLEQERqssfnAELSNKIKKLEEELRFSNELTRKLQAEAEElrnp 556
Cdd:COG4913   685 DDLAA---LEEQLEEL--------------EAELEELEEEL-----DELKGEIGRLEKELEQAEEELDELQDRLEA---- 738

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161076750  557 gkkkAPMLGVLGKSTSADAKFTRESLtrggsQEDPQHLQRELQDSIERETDLKDQlkfAEEELQRLRDR 625
Cdd:COG4913   739 ----AEDLARLELRALLEERFAAALG-----DAVERELRENLEERIDALRARLNR---AEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 861-1091 5.76e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  861 DTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDklpprTAKRVNDLTPK-SH 939
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA-----LEAELAELEKEiAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  940 LKKWVEELEDEISEM-RVMLSSSGTDQLKALQSAKGALEEdlrkckqklslaegdVQRLKLLNGSSSKVSELEQKLKRgd 1018
Cdd:COG4942    95 LRAELEAQKEELAELlRALYRLGRQPPLALLLSPEDFLDA---------------VRRLQYLKYLAPARREQAEELRA-- 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161076750 1019 eEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAEL 1091
Cdd:COG4942   158 -DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 825-1522 6.45e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.51  E-value: 6.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   825 AEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKldTLETENDKLAKENKRLLALRKASEKTGEVDQKMKEsLAQAQRE 904
Cdd:TIGR00618  192 LHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEK--ELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQL-LKQLRAR 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   905 RDELTARLKRMQLEAEDKLPPRTAKRvndLTPKShlkKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCK 984
Cdd:TIGR00618  269 IEELRAQEAVLEETQERINRARKAAP---LAAHI---KAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   985 QKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEA--KKLNSKLKDLEDKVK--KQEAQLKLGETSKSTWESQSKR-E 1059
Cdd:TIGR00618  343 QRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQslCKELDILQREQATIDTRTSAFRdL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1060 KEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKasKSDSKQVQDLKKQVEEVQASLS 1139
Cdd:TIGR00618  423 QGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTK--EQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1140 AEQKRYEDLNNHWEKlSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSE-AQKRIADLQAKALKt 1218
Cdd:TIGR00618  501 EEPCPLCGSCIHPNP-ARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEqMQEIQQSFSILTQC- 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1219 vngngaeyeRTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLsdynRIEQAQSSLNGHGARREAEIRELK 1298
Cdd:TIGR00618  579 ---------DNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKL----QPEQDLQDVRLHLQQCSQELALKL 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1299 EQLQSTELQMKSEVATVRLRYEQQVKNLSGE-----LTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGS 1373
Cdd:TIGR00618  646 TALHALQLTLTQERVREHALSIRVLPKELLAsrqlaLQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1374 MHSSDdddKSKIAYLEQQIGHLEDQLVESRLESSKiKTELVSERSANEIKISEMQSKlnefEEERVIGSGSTKLPGMKTK 1453
Cdd:TIGR00618  726 ASSSL---GSDLAAREDALNQSLKELMHQARTVLK-ARTEAHFNNNEEVTAALQTGA----ELSHLAAEIQFFNRLREED 797

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161076750  1454 LELSWQKEREDQQRLlqETSTLARDLRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAEL 1522
Cdd:TIGR00618  798 THLLKTLEAEIGQEI--PSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQL 864
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 965-1148 6.52e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 6.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  965 QLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKllngssSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKL 1044
Cdd:COG1579    11 DLQELDSELDRLEHRLKELPAELAELEDELAALE------ARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1045 GETSKStwesqskrekekLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDS--- 1121
Cdd:COG1579    85 VRNNKE------------YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEela 152

                         170       180       190
                  ....*....|....*....|....*....|.
gi 161076750 1122 ---KQVQDLKKQVEEVQASLSAE-QKRYEDL 1148
Cdd:COG1579   153 eleAELEELEAEREELAAKIPPElLALYERI 183
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 345-625 7.06e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 7.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   345 NGMQEQMKALKlELETMKTRAEKAEREKSDIL--LRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLR 422
Cdd:TIGR02168  670 SSILERRREIE-ELEEKIEELEEKIAELEKALaeLRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   423 MKELENKGSESELRRKLQAAEQicEELMEENQSAKKEILNLQAEMDEVQDTFRDDEvKAKTSLQKDLEKATKNCRILSFK 502
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERL--EEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   503 LKKSDRKIETLEQERQssfnaELSNKIKKLEEELRFSNELTRKLQAEAEELRnpgkkkapmlgvlgkstsadAKFTRESL 582
Cdd:TIGR02168  826 LESLERRIAATERRLE-----DLEEQIEELSEDIESLAAEIEELEELIEELE--------------------SELEALLN 880

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 161076750   583 TRGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDR 625
Cdd:TIGR02168  881 ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 960-1521 7.30e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 7.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   960 SSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKL--NSKLKDLEDKVKK 1037
Cdd:pfam02463  162 AAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLlyLDYLKLNEERIDL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1038 QEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsAKKSAEKSKSSLEKEIKDLKTKAS 1117
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEE--EELKSELLKLERRKVDDEEKLKES 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1118 KSDSKQVQDLKKQVEEVQASLSAEQKRYEDLnnhwEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDM 1197
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIK----REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1198 ARKLSEAQKRIADLQAKALKTVNGNgAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIE 1277
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDL-LKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1278 QAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNL----SGELTSMQRQCERFK--------KDRD 1345
Cdd:pfam02463  475 KETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRiisaHGRLGDLGVAVENYKvaistaviVEVS 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1346 AFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLES-SKIKTELVSERSANEIKI 1424
Cdd:pfam02463  555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAdEDDKRAKVVEGILKDTEL 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1425 SEMQSKLNEFEEERVIGSGSTKLPGMKTKLELSWQKEReDQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLDQI 1504
Cdd:pfam02463  635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELT-KELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713

                          570
                   ....*....|....*...
gi 161076750  1505 KRATE-EEMEEGRKKIAE 1521
Cdd:pfam02463  714 KLKLEaEELLADRVQEAQ 731
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
762-1326 1.08e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  762 AELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSngskssllslgtsssaaeKKVKTLNEELVQLRR 841
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------------------DRLEQLEREIERLER 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  842 TLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLA--LRKASEKTGEVDQ---KMKESLAQAQRERDELTARLKRMQ 916
Cdd:COG4913   353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAalLEALEEELEALEEalaEAEAALRDLRRELRELEAEIASLE 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  917 L---------------------EAEDKLPP--------------RTA-------KRVNDLTPKSHLK---KWVEE--LED 949
Cdd:COG4913   433 RrksniparllalrdalaealgLDEAELPFvgelievrpeeerwRGAiervlggFALTLLVPPEHYAaalRWVNRlhLRG 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  950 EISEMRVMLSSSGTDQLKA--------LQSAKGAL-------------------EEDLRKC----------KQKLSLAEG 992
Cdd:COG4913   513 RLVYERVRTGLPDPERPRLdpdslagkLDFKPHPFrawleaelgrrfdyvcvdsPEELRRHpraitragqvKGNGTRHEK 592

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  993 DVQRLKLLN---GSSSkvselEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQskrekEKLSSLEKD 1069
Cdd:COG4913   593 DDRRRIRSRyvlGFDN-----RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRL-----AEYSWDEID 662

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1070 MEKQAKEKEKLEAKISQLDA------ELLSAKKSAEKSKSSLEKEIKDLKTKASKSDsKQVQDLKKQVEEVQASLSAEQK 1143
Cdd:COG4913   663 VASAEREIAELEAELERLDAssddlaALEEQLEELEAELEELEEELDELKGEIGRLE-KELEQAEEELDELQDRLEAAED 741

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1144 R-----YEDLNNHWEKLSEETIL--MRAQLTTEKQSLQAELNASKQKIAEMdtiriertdMARKLSEAQKRIADLQAKAl 1216
Cdd:COG4913   742 LarlelRALLEERFAAALGDAVEreLRENLEERIDALRARLNRAEEELERA---------MRAFNREWPAETADLDADL- 811

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1217 ktvnGNGAEYER--TVLKN-KLAEKEHEYERLRRENEMN--IDLVFQLRKDNDDLngklsdYNRIEQAQSSLNGH----- 1286
Cdd:COG4913   812 ----ESLPEYLAllDRLEEdGLPEYEERFKELLNENSIEfvADLLSKLRRAIREI------KERIDPLNDSLKRIpfgpg 881

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 161076750 1287 -------GARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNL 1326
Cdd:COG4913   882 rylrleaRPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 840-1522 1.13e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.82  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   840 RRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEK-TGEVDQKMKESLAQAQRERDELTARLKRMQLE 918
Cdd:TIGR00606  237 REIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKdNSELELKMEKVFQGTDEQLNDLYHNHQRTVRE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   919 AEDKLPpRTAKRVNDLTPKShlkkwvEELEDEISEMrvmLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLK 998
Cdd:TIGR00606  317 KERELV-DCQRELEKLNKER------RLLNQEKTEL---LVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   999 LLNGSSSKVSELeqKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKE 1078
Cdd:TIGR00606  387 FSERQIKNFHTL--VIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQ 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1079 KLEAKISqldaELLSAKKSAEKSKSSLEKEIKDLKTKASKsdsKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEE 1158
Cdd:TIGR00606  465 QLEGSSD----RILELDQELRKAERELSKAEKNSLTETLK---KEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQM 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1159 TILMRAQLTTEKQSLQAELNASKQKIAEMDTI--RIERTDMARKLSEAQKRIADLQAKALKTVngNGAEYERTVLKNKLA 1236
Cdd:TIGR00606  538 EMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFpnKKQLEDWLHSKSKEINQTRDRLAKLNKEL--ASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1237 EKEHEYERLrrenEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQST------ELQMKS 1310
Cdd:TIGR00606  616 SKEEQLSSY----EDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCcpvcqrVFQTEA 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1311 EVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIgDLKANNTG--RQSRGSMHSSDDDDKSKIAYL 1388
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII-DLKEKEIPelRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1389 EQQIGHL--EDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVIGSGSTKLPGMKTKLELSWQKeREDQQ 1466
Cdd:TIGR00606  771 ETLLGTImpEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSK-IELNR 849

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 161076750  1467 RLLQETSTLARDLRQTLFEVERERDKERLESKRkldqiKRATEEEMEEGRKKIAEL 1522
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQR-----RQQFEEQLVELSTEVQSL 900
PRK01156 PRK01156
chromosome segregation protein; Provisional
 997-1540 1.47e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.29  E-value: 1.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  997 LKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEdkvKKQEAQLKLGETSKSTWESQSKrEKEKLSSLEKDMEKQAKE 1076
Cdd:PRK01156  175 IDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDE---KSHSITLKEIERLSIEYNNAMD-DYNNLKSALNELSSLEDM 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1077 KEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKS---------DSKQVQDLKKQVEEVQASLSA------- 1140
Cdd:PRK01156  251 KNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNrnyindyfkYKNDIENKKQILSNIDAEINKyhaiikk 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1141 -------------EQKRYEDLNNHWEKLSE------------ETILMRAQLTTEKQSLQAELNASKQKIAEM--DTIRIE 1193
Cdd:PRK01156  331 lsvlqkdyndyikKKSRYDDLNNQILELEGyemdynsylksiESLKKKIEEYSKNIERMSAFISEILKIQEIdpDAIKKE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1194 RTDMARKLSEAQKRIADLQAKalktvngngaeyeRTVLKNKLAEKEHEYERLRREN-------EMNIDLVFQLRKD-NDD 1265
Cdd:PRK01156  411 LNEINVKLQDISSKVSSLNQR-------------IRALRENLDELSRNMEMLNGQSvcpvcgtTLGEEKSNHIINHyNEK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1266 LNGKLSDYNRIEQAQSSLNghgarreaeirELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRD 1345
Cdd:PRK01156  478 KSRLEEKIREIEIEVKDID-----------EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHD 546

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1346 AFKQML-EVAQKKIGDLKANNTGRQSRGSMHSSDDDD--KSKIAYLEQQIGHLEDQLVEsrlesskIKTELVSERSANEI 1422
Cdd:PRK01156  547 KYEEIKnRYKSLKLEDLDSKRTSWLNALAVISLIDIEtnRSRSNEIKKQLNDLESRLQE-------IEIGFPDDKSYIDK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1423 KISEMQSKLNEFEEERvigsgstklpgmktklelswqKEREDQQRLLQETSTLARDLRQTLFEVErERDKERLESKRKLD 1502
Cdd:PRK01156  620 SIREIENEANNLNNKY---------------------NEIQENKILIEKLRGKIDNYKKQIAEID-SIIPDLKEITSRIN 677

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 161076750 1503 QIkratEEEMEEGRKKIAELQCDLLELRDVHAKLRTSN 1540
Cdd:PRK01156  678 DI----EDNLKKSRKALDDAKANRARLESTIEILRTRI 711
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 827-1537 1.60e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   827 KKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKasEKTGEVDQKMKESLAQAQRERD 906
Cdd:pfam01576   15 QKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARK--QELEEILHELESRLEEEEERSQ 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   907 ELTARLKRMQ---LEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRvmlsssgtDQLKALQSAKGALEEDLRKC 983
Cdd:pfam01576   93 QLQNEKKKMQqhiQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLE--------DQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   984 KQKLSLAEGDVQRL-KLLNGSSSKVSELEQKLKR---GDEEAKKLNSKLK----DLEDKVKKQEAQLklgetskSTWESQ 1055
Cdd:pfam01576  165 TSNLAEEEEKAKSLsKLKNKHEAMISDLEERLKKeekGRQELEKAKRKLEgestDLQEQIAELQAQI-------AELRAQ 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1056 SKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDA---ELLSAKKSAEKSKSSLEKEIKDLktkasksdSKQVQDLKKQVE 1132
Cdd:pfam01576  238 LAKKEEELQAALARLEEETAQKNNALKKIRELEAqisELQEDLESERAARNKAEKQRRDL--------GEELEALKTELE 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1133 EVQASLSAEQ----KRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQkiaEMDTIRIERTDMARKLSEAQKRI 1208
Cdd:pfam01576  310 DTLDTTAAQQelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTE---QLEQAKRNKANLEKAKQALESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1209 ADLQAKaLKTVNGNGAEYE--RTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSdynrieqaqsSLNGH 1286
Cdd:pfam01576  387 AELQAE-LRTLQQAKQDSEhkRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN----------EAEGK 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1287 GARREAEIRELKEQLQSTELQMKSEVATvRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLK---- 1362
Cdd:pfam01576  456 NIKLSKDVSSLESQLQDTQELLQEETRQ-KLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKkkle 534

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1363 ----ANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSAneikISEMQSKLNEFE--- 1435
Cdd:pfam01576  535 edagTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQL----VSNLEKKQKKFDqml 610

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1436 -EERVIgsgSTKLPGMKTKLElswQKEREDQQRLLQETSTLaRDLRQTLFEVERERDKERLE-------------SKRKL 1501
Cdd:pfam01576  611 aEEKAI---SARYAEERDRAE---AEAREKETRALSLARAL-EEALEAKEELERTNKQLRAEmedlvsskddvgkNVHEL 683

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 161076750  1502 DQIKRATEEEMEEGRKKIAELQCDLLELRDvhAKLR 1537
Cdd:pfam01576  684 ERSKRALEQQVEEMKTQLEELEDELQATED--AKLR 717
PTZ00121 PTZ00121
MAEBL; Provisional
 182-629 1.78e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  182 AERVRKMNLLKKQRSLNSRENSRERSVPRREEESESTATPTPVVPDRPERSKSGTSLNQLAQAEQKraALPPKKVAVAST 261
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK--AEEAKKADEAKK 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  262 TTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVRRKEADSVASKEIKRQTvPAASISHSNSTSSTASTASKS 341
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKA-DAAKKKAEEKKKADEAKKKAE 1401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  342 QDTNGMQEQMKAL--KLELETMKTRAEkaEREKSDILLRRLASmdtasnrtaASEALNLQQKLNEMK--EQLDRVTEDKR 417
Cdd:PTZ00121 1402 EDKKKADELKKAAaaKKKADEAKKKAE--EKKKADEAKKKAEE---------AKKADEAKKKAEEAKkaEEAKKKAEEAK 1470

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  418 KLNLRMKELENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKncr 497
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK--- 1547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  498 ilSFKLKKSD--RKIETLEQERQSSFNAELSNKIKKLEEELRFSNEltRKLQAEAEELRNPGKKKAPMLgvlgkSTSADA 575
Cdd:PTZ00121 1548 --ADELKKAEelKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE--ARIEEVMKLYEEEKKMKAEEA-----KKAEEA 1618

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 161076750  576 KFTRESLTRggsQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKR 629
Cdd:PTZ00121 1619 KIKAEELKK---AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK 1669
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 769-1194 2.05e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 49.82  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   769 ELNEQEASILRL--KVEDLEKENAESKKYVRELQAKLrqdssngskssllslgtssSAAEKKVKTLNEELVQLRRTLTEK 846
Cdd:pfam10174  297 ELSKKESELLALqtKLETLTNQNSDCKQHIEVLKESL-------------------TAKEQRAAILQTEVDALRLRLEEK 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   847 EQTVDSLKNQLSKldtLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLK-RMQLEAEDKlpp 925
Cdd:pfam10174  358 ESFLNKKTKQLQD---LTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKeRVKSLQTDS--- 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   926 rtakrVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKgaleEDLRKCKQKLSLAEGDVQ-RLKLLNGSS 1004
Cdd:pfam10174  432 -----SNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLK----KENKDLKEKVSALQPELTeKESSLIDLK 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1005 SKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTwESQSKREKEKLSSLEKDMEKQAKEKEKLEAKI 1084
Cdd:pfam10174  503 EHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEA-VRTNPEINDRIRLLEQEVARYKEESGKAQAEV 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1085 SQL-------DAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASL--------SAEQKRYEDLN 1149
Cdd:pfam10174  582 ERLlgilrevENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARrrednladNSQQLQLEELM 661

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 161076750  1150 NHWEKLSEETILMRAQLTTEKQSLQaelnaskQKIAEMDTIRIER 1194
Cdd:pfam10174  662 GALEKTRQELDATKARLSSTQQSLA-------EKDGHLTNLRAER 699
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 762-1402 2.73e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 2.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   762 AELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLrqdssNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRr 841
Cdd:pfam01576  232 AELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQI-----SELQEDLESERAARNKAEKQRRDLGEELEALK- 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   842 tlTEKEQTVDSLKNQLSKLDTLETENDKLakenkrllalrkasEKTGEVDQKMKEslAQAQRERDELTARLKRMQLEAED 921
Cdd:pfam01576  306 --TELEDTLDTTAAQQELRSKREQEVTEL--------------KKALEEETRSHE--AQLQEMRQKHTQALEELTEQLEQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   922 klpprtAKRVndltpKSHLKKWVEELEDEISEMRVmlsssgtdQLKALQSAKGALEEDLRKCKQKLS-----LAEGDVQR 996
Cdd:pfam01576  368 ------AKRN-----KANLEKAKQALESENAELQA--------ELRTLQQAKQDSEHKRKKLEGQLQelqarLSESERQR 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   997 LKL----------LNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQlklgetsKSTWESQSKREKEKLSSL 1066
Cdd:pfam01576  429 AELaeklsklqseLESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQ-------KLNLSTRLRQLEDERNSL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1067 EKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEkeikdLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYE 1146
Cdd:pfam01576  502 QEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLE-----ALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKN 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1147 DLNNHWEKLSEETILMRAQLTT-EK------QSLQAELNASKQKIAEMDTIRIERTD-------MARKLSEAQKRIADL- 1211
Cdd:pfam01576  577 RLQQELDDLLVDLDHQRQLVSNlEKkqkkfdQMLAEEKAISARYAEERDRAEAEAREketralsLARALEEALEAKEELe 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1212 -QAKALKtvngngAEYERTV-LKNKLAEKEHEYERLRRENEMNI-DLVFQLRKDNDDLNGKLSDYNRIE--------QAQ 1280
Cdd:pfam01576  657 rTNKQLR------AEMEDLVsSKDDVGKNVHELERSKRALEQQVeEMKTQLEELEDELQATEDAKLRLEvnmqalkaQFE 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1281 SSLNGHGARREAEIRELKEQLQSTELQMKSEvATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGD 1360
Cdd:pfam01576  731 RDLQARDEQGEEKRRQLVKQVRELEAELEDE-RKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKD 809

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 161076750  1361 LKAN-NTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVES 1402
Cdd:pfam01576  810 LQRElEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAAS 852
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
774-951 2.96e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.09  E-value: 2.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  774 EASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSsllslgtsssaaEKKVKTLNEELVQLRRTLTEKEQTVDSL 853
Cdd:COG2433   379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRL------------EEQVERLEAEVEELEAELEEKDERIERL 446

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  854 KNQLSKLDTletendklaKENKRLLALRKASEKTGEVDQKMKEsLAQAQRERDELTARLKRMQ----LEAEDKLPPrtAK 929
Cdd:COG2433   447 ERELSEARS---------EERREIRKDREISRLDREIERLERE-LEEERERIEELKRKLERLKelwkLEHSGELVP--VK 514

                         170       180
                  ....*....|....*....|..
gi 161076750  930 RVNDLTpkshlKKWVEELEDEI 951
Cdd:COG2433   515 VVEKFT-----KEAIRRLEEEY 531
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1063-1510 2.98e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 2.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1063 LSSLEKDMEKQAKEKEKLEAKISQLDAELLsakksaekskSSLEKEIKDLKTKAsksdsKQVQDLKKQVEEVQASLSAEQ 1142
Cdd:COG4717    44 RAMLLERLEKEADELFKPQGRKPELNLKEL----------KELEEELKEAEEKE-----EEYAELQEELEELEEELEELE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1143 KRYEDLNNHWEKLseETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGN 1222
Cdd:COG4717   109 AELEELREELEKL--EKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1223 GAEYERTV---------LKNKLAEKEHEYERLRRENEmnidlvfQLRKDNDDLNGKL---SDYNRIEQAQSSLNGHGAR- 1289
Cdd:COG4717   187 SLATEEELqdlaeeleeLQQRLAELEEELEEAQEELE-------ELEEELEQLENELeaaALEERLKEARLLLLIAAALl 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1290 --------------REAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSG----ELTSMQRQCERFKKDRDAFKQML 1351
Cdd:COG4717   260 allglggsllslilTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAleelEEEELEELLAALGLPPDLSPEEL 339

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1352 EVAQKKIGDLKANNTGRQsrgsmhssDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKL 1431
Cdd:COG4717   340 LELLDRIEELQELLREAE--------ELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQL 411

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1432 NEFEEERVIGSGSTKLPGMKTKLELSWQKEREDQQRLLQETSTLARdLRQTLFEVERERDKERLESKR--KLDQIKRATE 1509
Cdd:COG4717   412 EELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAE-LEAELEQLEEDGELAELLQELeeLKAELRELAE 490


                  .
gi 161076750 1510 E 1510
Cdd:COG4717   491 E 491
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
944-1357 3.22e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  944 VEELEDEISEMRvmlssSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSS---KVSELEQKLKRGDEE 1020
Cdd:COG4717    73 LKELEEELKEAE-----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyqELEALEAELAELPER 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1021 AKKLNSKLKDLEDKVKKQEAQL----KLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakk 1096
Cdd:COG4717   148 LEELEERLEELRELEEELEELEaelaELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL----- 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1097 saekskSSLEKEIKDLKTKASKSDSKQVQDLKKQ---VEEVQASLSAEQKRYEDLNNHWEKLS---------EETILMRA 1164
Cdd:COG4717   223 ------EELEEELEQLENELEAAALEERLKEARLlllIAAALLALLGLGGSLLSLILTIAGVLflvlgllalLFLLLARE 296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1165 QLTTEKQSLQAELNASKQKIAEMDTIRI-ERTDMARKLSEAQKRIADLQAKALKTvngngaeyertvLKNKLAEKEHEYE 1243
Cdd:COG4717   297 KASLGKEAEELQALPALEELEEEELEELlAALGLPPDLSPEELLELLDRIEELQE------------LLREAEELEEELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1244 RLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTEL-QMKSEVATVR---LRY 1319
Cdd:COG4717   365 LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEeELEEELEELEeelEEL 444

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 161076750 1320 EQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKK 1357
Cdd:COG4717   445 EEELEELREELAELEAELEQLEEDGELAELLQELEELK 482
PTZ00121 PTZ00121
MAEBL; Provisional
 182-628 4.08e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 4.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  182 AERVRKMNLLKKQRSLNSRENSRERSVPRREEESESTATPTpvvpdRPERSKSGTSLNQLAQAEQKRAALPPKKVAVAST 261
Cdd:PTZ00121 1184 AEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAK-----KAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  262 TTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVRRKEADSVASKEIKRQTVPAASISHSNSTSSTASTASKS 341
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  342 QDTNGMQE----QMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKR 417
Cdd:PTZ00121 1339 EEAKKAAEaakaEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK 1418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  418 KLNLRMKELENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRD--DEVKAKTSLQKDLEKATKN 495
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKKKAEEAKKK 1498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  496 CRILSFK---------LKKSDRKIETLE----QERQSSFNAELSNKIKKLE-----EELRFSNELTRKLQA-EAEELRNP 556
Cdd:PTZ00121 1499 ADEAKKAaeakkkadeAKKAEEAKKADEakkaEEAKKADEAKKAEEKKKADelkkaEELKKAEEKKKAEEAkKAEEDKNM 1578

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 161076750  557 GKKKAPMLGVLGKSTSADAKFTRESLTRGGSQE----DPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERK 628
Cdd:PTZ00121 1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEakkaEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1116-1410 4.60e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1116 ASKSDSKQVQDLKKQVEEVQASLSAEQKRyedlnnhweklseetilmRAQLTTEKQSLQAELNASKQKIAEmdtiriert 1195
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKE------------------LAALKKEEKALLKQLAALERRIAA--------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1196 dMARKLSEAQKRIADLQAKAlktvngNGAEYERTVLKNKLAEKEHEYERLRRENEMNidlvfqLRKDNDDLNGKLSDYNR 1275
Cdd:COG4942    67 -LARRIRALEQELAALEAEL------AELEKEIAELRAELEAQKEELAELLRALYRL------GRQPPLALLLSPEDFLD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1276 IEQAQSSLNGHGARREAEIRELKEQLQstelqmksEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQ 1355
Cdd:COG4942   134 AVRRLQYLKYLAPARREQAEELRADLA--------ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLE 205

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 161076750 1356 KKIGDLKANNTGRQsrgsmhSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIK 1410
Cdd:COG4942   206 KELAELAAELAELQ------QEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 880-1403 5.31e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 5.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   880 LRKASEKTGEVDQKMKEsLAQAQRERDELTARLKrMQLEAEDKLPPRTAK-RVNDLTPKSHLKKWVEELEDEISEMRvml 958
Cdd:pfam01576   14 LQKVKERQQKAESELKE-LEKKHQQLCEEKNALQ-EQLQAETELCAEAEEmRARLAARKQELEEILHELESRLEEEE--- 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   959 sssgtDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSS-SKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKK 1037
Cdd:pfam01576   89 -----ERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTeAKIKKLEEDILLLEDQNSKLSKERKLLEERISE 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1038 QEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakKSAEKSKSSLEKEIKDLKTKAS 1117
Cdd:pfam01576  164 FTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGES----TDLQEQIAELQAQIAELRAQLA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1118 KSDsKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETIL---MRAQLTTEKQSLQAELNASKQKI---------- 1184
Cdd:pfam01576  240 KKE-EELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESeraARNKAEKQRRDLGEELEALKTELedtldttaaq 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1185 AEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEyertvlknklaEKEHEYERLRReNEMNIDLVFQ-LRKDN 1263
Cdd:pfam01576  319 QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALE-----------ELTEQLEQAKR-NKANLEKAKQaLESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1264 DDLNGKLSDynrIEQAQSSLNGHGARREAEIRELKEQLQSTELQmKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKD 1343
Cdd:pfam01576  387 AELQAELRT---LQQAKQDSEHKRKKLEGQLQELQARLSESERQ-RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKD 462

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161076750  1344 RDAFKQMLEVAQKKIGD---LKANNTGR-----QSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESR 1403
Cdd:pfam01576  463 VSSLESQLQDTQELLQEetrQKLNLSTRlrqleDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMK 530
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1008-1539 5.95e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 5.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1008 SELEQKLKRGDEEAKKLnSKLKDLEDKVKKQEAQLKLGETSKSTWESQskREKEKLSSLEKDMEKQAKEKEKLEAKISQL 1087
Cdd:COG4913   238 ERAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYLRAALRLW--FAQRRLELLEAELEELRAELARLEAELERL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1088 DAELlsakksaekskSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLT 1167
Cdd:COG4913   315 EARL-----------DALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1168 TEKQSLQAELNASKQKIAEMDTiriERTDMARKLSEAQKRIADLQAkalktvngngaeyERTVLKNKLAEKEHEYERLRR 1247
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEA-------------EIASLERRKSNIPARLLALRD 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1248 E-----NEMNIDLVF-----QLRKDNDDLNGKlsdynrIEQAqssLNGHG------ARREAEIRELKEQLQSTElqmkse 1311
Cdd:COG4913   448 AlaealGLDEAELPFvgeliEVRPEEERWRGA------IERV---LGGFAltllvpPEHYAAALRWVNRLHLRG------ 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1312 vatvRLRYEqqvknlsgELTSMQRQCERFKKDRDAFKQMLEVAQKKIGD-LKA-----------------NNTGRQ---- 1369
Cdd:COG4913   513 ----RLVYE--------RVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAelgrrfdyvcvdspeelRRHPRAitra 580

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1370 ----SRGSMHSSDDDD------------KSKIAYLEQQIGHLEDQLVESRLESSKIKTEL------------VSERSANE 1421
Cdd:COG4913   581 gqvkGNGTRHEKDDRRrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELdalqerrealqrLAEYSWDE 660

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1422 IKISEMQSKLNEFEEERV-IGSGSTKLPGMKTKLElSWQKEREDQQRLLQETSTLARDLRQTLFEVERERDkerlESKRK 1500
Cdd:COG4913   661 IDVASAEREIAELEAELErLDASSDDLAALEEQLE-ELEAELEELEEELDELKGEIGRLEKELEQAEEELD----ELQDR 735

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 161076750 1501 LDQI-KRATEEEMEEGRKKIAELQCDLLElRDVHAKLRTS 1539
Cdd:COG4913   736 LEAAeDLARLELRALLEERFAAALGDAVE-RELRENLEER 774
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 834-1538 6.47e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   834 EELVQLRRTLTEKEQTVDSLKNQLsKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRErdELTARLK 913
Cdd:pfam12128  357 ENLEERLKALTGKHQDVTAKYNRR-RSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE--QLEAGKL 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   914 RMQlEAEDKLPPRTAK---RVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLkALQSAKGALEEDLRKCKQKLSLA 990
Cdd:pfam12128  434 EFN-EEEYRLKSRLGElklRLNQATATPELLLQLENFDERIERAREEQEAANAEVE-RLQSELRQARKRRDQASEALRQA 511

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   991 EGDVQRLKllngssskvSELEQKLKRGDEEAKKL----NSKLKDLEDKVKKQEAQLKLGETS--KSTWESQSKREKE--- 1061
Cdd:pfam12128  512 SRRLEERQ---------SALDELELQLFPQAGTLlhflRKEAPDWEQSIGKVISPELLHRTDldPEVWDGSVGGELNlyg 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1062 -KLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKtKASKSDSKQVQDLKkQVEEVQASLSA 1140
Cdd:pfam12128  583 vKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELE-KASREETFARTALK-NARLDLRRLFD 660

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1141 EQKRYEDlnnhweKLSEETILMRAQLTTEKQSLQAELNASKQKIAEM-----DTIRIERTDMARKLSEAQKRIaDLQAKA 1215
Cdd:pfam12128  661 EKQSEKD------KKNKALAERKDSANERLNSLEAQLKQLDKKHQAWleeqkEQKREARTEKQAYWQVVEGAL-DAQLAL 733

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1216 LKTvngnGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYnrieqaqsslnghgARREAEIR 1295
Cdd:pfam12128  734 LKA----AIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERI--------------AVRRQEVL 795

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1296 ELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMH 1375
Cdd:pfam12128  796 RYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATL 875

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1376 SSDDDDKSkiayLEQQIGHLEDQLVE--SRLESSKIKTELVSERSANEIKiSEMQSKLNEF-----EEERVIGSGSTKLp 1448
Cdd:pfam12128  876 KEDANSEQ----AQGSIGERLAQLEDlkLKRDYLSESVKKYVEHFKNVIA-DHSGSGLAETweslrEEDHYQNDKGIRL- 949

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1449 gmktklelswQKEREDQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELqCDLLE 1528
Cdd:pfam12128  950 ----------LDYRKLVPYLEQWFDVRVPQSIMVLREQVSILGVDLTEFYDVLADFDRRIASFSRELQREVGEE-AFFEG 1018

                          730
                   ....*....|
gi 161076750  1529 LRDVHAKLRT 1538
Cdd:pfam12128 1019 VSESAVRIRS 1028
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 888-1580 6.75e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 6.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   888 GEVDQKMKESlaqaQRERDELTARLkrMQLEAEDKLPPRTAKRVNDLTPKSH-LKKWVEELEDEISEMRVMLSSSG---T 963
Cdd:TIGR00618  152 GEFAQFLKAK----SKEKKELLMNL--FPLDQYTQLALMEFAKKKSLHGKAElLTLRSQLLTLCTPCMPDTYHERKqvlE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   964 DQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNsklkdLEDKVKKQEAQLK 1043
Cdd:TIGR00618  226 KELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERIN-----RARKAAPLAAHIK 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1044 LGETSKSTWESQSKREKEKLSSLEKD-MEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKAS----- 1117
Cdd:TIGR00618  301 AVTQIEQQAQRIHTELQSKMRSRAKLlMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHtltqh 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1118 -----------KSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAE 1186
Cdd:TIGR00618  381 ihtlqqqkttlTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1187 MdtIRIERTDMARKLSEAQKRIADLQAKALKTVNGNgaeyertvLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDL 1266
Cdd:TIGR00618  461 L--QESAQSLKEREQQLQTKEQIHLQETRKKAVVLA--------RLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRM 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1267 NGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQStELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDA 1346
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQE-IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1347 fKQMLEVAQKKIGDLKANNtgRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERsaNEIKISE 1426
Cdd:TIGR00618  610 -LACEQHALLRKLQPEQDL--QDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLAS--RQLALQK 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1427 MQSKLNEFEEER-VIGSGSTKLPGMKTKLELSWQKEREDQQRLLQETSTLARD---LRQTLFEVERERD---KERLE--- 1496
Cdd:TIGR00618  685 MQSEKEQLTYWKeMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARedaLNQSLKELMHQARtvlKARTEahf 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1497 --SKRKLDQIKRATEEEMEEG--RKKIAELQCDLLELRDVHAKLRTSNEKLRRERERYEKELIKRRMEADGGDRKVGALL 1572
Cdd:TIGR00618  765 nnNEEVTAALQTGAELSHLAAeiQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATL 844


                   ....*...
gi 161076750  1573 QTVDELVK 1580
Cdd:TIGR00618  845 GEITHQLL 852
PRK11281 PRK11281
mechanosensitive channel MscK;
1132-1522 8.26e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 8.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1132 EEVQASLSAEQKRyeDLNNHWEKLS----EETILMRAQLTTEKQslqaELNASKQKIAEMDtiriertdmaRKLSEAQKR 1207
Cdd:PRK11281   39 ADVQAQLDALNKQ--KLLEAEDKLVqqdlEQTLALLDKIDRQKE----ETEQLKQQLAQAP----------AKLRQAQAE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1208 IADLQAKALKTVNGNGAEYERTVLKNKLAEkeheyerlrRENEMNidlvfQLRKDNDDLNGKLSDYN-RIEQAQSSLNGH 1286
Cdd:PRK11281  103 LEALKDDNDEETRETLSTLSLRQLESRLAQ---------TLDQLQ-----NAQNDLAEYNSQLVSLQtQPERAQAALYAN 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1287 GARreaeIRELKEQLQSTELQMKSevatvrLRYEQQVKnLSGELTSMQRQCERFKKdrdafkqmlevaqkkigdLKANNT 1366
Cdd:PRK11281  169 SQR----LQQIRNLLKGGKVGGKA------LRPSQRVL-LQAEQALLNAQNDLQRK------------------SLEGNT 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1367 GRQSRGSmhSSDDDDKSKIAYLEQQIGHLEDQLVESRLESS-KIKTELVSERSANEIKISEM---QSKLNEFEEERVIGS 1442
Cdd:PRK11281  220 QLQDLLQ--KQRDYLTARIQRLEHQLQLLQEAINSKRLTLSeKTVQEAQSQDEAARIQANPLvaqELEINLQLSQRLLKA 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1443 gSTKLPG-------MKTKLELSWQKER--EDQQRLLQETSTLAR-----------------------DLRQTLFEVERER 1490
Cdd:PRK11281  298 -TEKLNTltqqnlrVKNWLDRLTQSERniKEQISVLKGSLLLSRilyqqqqalpsadliegladriaDLRLEQFEINQQR 376

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 161076750 1491 DK--------ERLESKRK---LDQIKRATEEEMEEGRKKIAEL 1522
Cdd:PRK11281  377 DAlfqpdayiDKLEAGHKsevTDEVRDALLQLLDERRELLDQL 419
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1057-1530 1.26e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1057 KREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQA 1136
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1137 SLSAEQKRYEDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRierTDMARKLSEAQKRIAdlqaKAL 1216
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMS---TMHFRSLGSAISKIL----REL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1217 KTvngngaeyERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKD----------------NDDLNGKLSDYNRIeQAQ 1280
Cdd:pfam15921  230 DT--------EISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDrieqliseheveitglTEKASSARSQANSI-QSQ 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1281 SSLNGHGARREAEI--RELKEqLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKI 1358
Cdd:pfam15921  301 LEIIQEQARNQNSMymRQLSD-LESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1359 GDLKANNTGRQSRGSMHSS------DDDDKSKIAyleqqIGHLEDQLVESRLESSKIKTELVSERS----ANEIKISEMQ 1428
Cdd:pfam15921  380 QKLLADLHKREKELSLEKEqnkrlwDRDTGNSIT-----IDHLRRELDDRNMEVQRLEALLKAMKSecqgQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1429 SKLNEFEEervIGSGSTKLPGMKTKLElSWQKEREDQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLDQIKRAT 1508
Cdd:pfam15921  455 GKNESLEK---VSSLTAQLESTKEMLR-KVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKL 530

                          490       500
                   ....*....|....*....|....*.
gi 161076750  1509 EE----EMEEGRKKIAELQCDLLELR 1530
Cdd:pfam15921  531 QElqhlKNEGDHLRNVQTECEALKLQ 556
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 753-1081 1.56e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.96  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  753 EGISDEDDPAELRILLELNEQEAS----ILRLKVEDLEKENaeskkyVRELQAKLRQDSSNGSKSSllslgtsssaaEKK 828
Cdd:PTZ00108 1063 EEEGAEEDDEADDEDDEEELGAAVsydyLLSMPIWSLTKEK------VEKLNAELEKKEKELEKLK-----------NTT 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  829 VKTL-NEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDE 907
Cdd:PTZ00108 1126 PKDMwLEDLDKFEEALEEQEEVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDE 1205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  908 LT-ARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDL--RKCK 984
Cdd:PTZ00108 1206 KRkLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSavQYSP 1285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  985 QKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLS 1064
Cdd:PTZ00108 1286 PPPSKRPDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSS 1365

                         330
                  ....*....|....*..
gi 161076750 1065 SLEKDMEKQAKEKEKLE 1081
Cdd:PTZ00108 1366 EDDDDSEVDDSEDEDDE 1382
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 940-1521 2.60e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   940 LKKWVEELEDEISEMRVMLSSSGT---DQLKALQSAKGA-------LEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSE 1009
Cdd:pfam05483   90 IKKWKVSIEAELKQKENKLQENRKiieAQRKAIQELQFEnekvslkLEEEIQENKDLIKENNATRHLCNLLKETCARSAE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1010 LEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKL-GETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKL-------- 1080
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVqAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQvsllliqi 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1081 ---EAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSD--SKQVQDLKKQveeVQASLSAEQKRYEDLnnhweKL 1155
Cdd:pfam05483  250 tekENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDhlTKELEDIKMS---LQRSMSTQKALEEDL-----QI 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1156 SEETIlmrAQLTTEKQSLQAELNASKQK----IAEMDTIRIERTDMARKLSEAQKRIAD-LQAKALKTVNGNGAEYERTV 1230
Cdd:pfam05483  322 ATKTI---CQLTEEKEAQMEELNKAKAAhsfvVTEFEATTCSLEELLRTEQQRLEKNEDqLKIITMELQKKSSELEEMTK 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1231 LKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAqsslnghgarREAEIRELKEQLQSTElqmks 1310
Cdd:pfam05483  399 FKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQA----------REKEIHDLEIQLTAIK----- 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1311 evaTVRLRYEQQVKNLSGELTSmqrqcERFKK-DRDAFKQMLEVAQKKIGDLKANNTGRQSRgsmHSSD-DDDKSKIAYL 1388
Cdd:pfam05483  464 ---TSEEHYLKEVEDLKTELEK-----EKLKNiELTAHCDKLLLENKELTQEASDMTLELKK---HQEDiINCKKQEERM 532

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1389 EQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVIGSGSTKLPGMK-TKLELSWQKEREDQQR 1467
Cdd:pfam05483  533 LKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKcNNLKKQIENKNKNIEE 612

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1468 LLQETSTL-----ARDLRQTLFEVERERDKERLES-KRKLDQIKRATEEEMEEgrKKIAE 1521
Cdd:pfam05483  613 LHQENKALkkkgsAENKQLNAYEIKVNKLELELASaKQKFEEIIDNYQKEIED--KKISE 670
PTZ00121 PTZ00121
MAEBL; Provisional
 357-629 2.68e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  357 ELETMKTRAEKAEREKSDILLRRL--ASMDTASNRTAASEALNlQQKLNEMKEQLD-------RVTEDKRKLNLRMKELE 427
Cdd:PTZ00121 1234 EAKKDAEEAKKAEEERNNEEIRKFeeARMAHFARRQAAIKAEE-ARKADELKKAEEkkkadeaKKAEEKKKADEAKKKAE 1312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  428 NKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSlQKDLEKATKNCRILSfklKKSD 507
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA-EKKKEEAKKKADAAK---KKAE 1388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  508 RKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQA--EAEELRNPG--KKKAPMLgvlgKSTSADAKFTRESLT 583
Cdd:PTZ00121 1389 EKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkKADEAKKKAeeAKKADEA----KKKAEEAKKAEEAKK 1464

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 161076750  584 RGGSQEDPQHLQRELQdsierETDLKDQLKFAEEELQRLRDRERKR 629
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAE-----EAKKADEAKKKAEEAKKKADEAKKA 1505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1056-1523 2.82e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 2.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1056 SKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLK--KQVEE 1133
Cdd:PRK03918  177 RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESleGSKRK 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1134 VQASLSAEQKRYEDLNNHWEKLSEETilmraqlttekqslqAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQA 1213
Cdd:PRK03918  257 LEEKIRELEERIEELKKEIEELEEKV---------------KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1214 KAlktvngngAEYERTVlkNKLAEKEHEYERLRRENEmnidlvfQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARR--- 1290
Cdd:PRK03918  322 EI--------NGIEERI--KELEEKEERLEELKKKLK-------ELEKRLEELEERHELYEEAKAKKEELERLKKRLtgl 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1291 -----EAEIREL---KEQLQSTELQMKSEVATVRLRYEQQVKNLSgELTSMQRQC----------------ERFKKDRDA 1346
Cdd:PRK03918  385 tpeklEKELEELekaKEEIEEEISKITARIGELKKEIKELKKAIE-ELKKAKGKCpvcgrelteehrkellEEYTAELKR 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1347 FKQMLEVAQKKIGDLKAnntgRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSE--RSANEIK- 1423
Cdd:PRK03918  464 IEKELKEIEEKERKLRK----ELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKlkEKLIKLKg 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1424 -ISEMQSKLNEFEE--------ERVIGSGSTKLPGMKTKLELSWQKEREDQQRLLQETSTL------ARDLRQTLFEVER 1488
Cdd:PRK03918  540 eIKSLKKELEKLEElkkklaelEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFyneyleLKDAEKELEREEK 619

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 161076750 1489 ERDKERLESKRKLDQIKRaTEEEMEEGRKKIAELQ 1523
Cdd:PRK03918  620 ELKKLEEELDKAFEELAE-TEKRLEELRKELEELE 653
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1064-1317 3.01e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1064 SSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaekskSSLEKEIKDLKTKA--------SKSDSKQVQDLKKQVEEVQ 1135
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKEL-----------EEAEAALEEFRQKNglvdlseeAKLLLQQLSELESQLAEAR 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1136 ASLSAEQKRYEDLNNhwEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRierTDMARKLSEAQKRIADLQAKA 1215
Cdd:COG3206   233 AELAEAEARLAALRA--QLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY---TPNHPDVIALRAQIAALRAQL 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1216 lktvngngaeyeRTVLKNKLAEKEHEYERLRRENEmnidlvfQLRKDNDDLNGKLSDYNRIEQAQSSLNghgarREAEI- 1294
Cdd:COG3206   308 ------------QQEAQRILASLEAELEALQAREA-------SLQAQLAQLEARLAELPELEAELRRLE-----REVEVa 363

                         250       260
                  ....*....|....*....|....*..
gi 161076750 1295 ----RELKEQLQSTELQMKSEVATVRL 1317
Cdd:COG3206   364 relyESLLQRLEEARLAEALTVGNVRV 390
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1000-1224 3.14e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1000 LNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEK 1079
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1080 LEAKISQLDA--------ELLSAKKSAEKSKSSLEKEIKDLKtkaskSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNH 1151
Cdd:COG3883    98 SGGSVSYLDVllgsesfsDFLDRLSALSKIADADADLLEELK-----ADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161076750 1152 WEKLSEETILMRAQLTTEKQSLQAELnASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGA 1224
Cdd:COG3883   173 LEAQQAEQEALLAQLSAEEAAAEAQL-AELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
CagA_N pfam18971
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...
 424-617 3.16e-04

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.


Pssm-ID: 408741 [Multi-domain]  Cd Length: 876  Bit Score: 45.92  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   424 KELENKGSESELrrKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKtslQKDLEkatkncrilsfkl 503
Cdd:pfam18971  559 RNLENKLTAKGL--SLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKA---QKDLE------------- 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   504 kKSDRKIETLEQERQssfnaelsnkiKKLEEELRFSNELTRKLQAEAEelrnpgkkKAPMLGVLGKSTSADAKFTRESLT 583
Cdd:pfam18971  621 -KSLRKREHLEKEVE-----------KKLESKSGNKNKMEAKAQANSQ--------KDEIFALINKEANRDARAIAYTQN 680

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 161076750   584 RGGsqedpqhLQRELQDSIER-ETDLKDQLKFAEE 617
Cdd:pfam18971  681 LKG-------IKRELSDKLEKiSKDLKDFSKSFDE 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 877-1120 3.19e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  877 LLALRKASEKTGEVDQKMKEsLAQAQRERDELTARLKRMQLEAEDklpprTAKRVNDLTPK-SHLKKWVEELEDEISEMR 955
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKA-----LLKQLAALERRiAALARRIRALEQELAALE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  956 vmlsssgtDQLKALQSAKGALEEDLRKCKQKLSL------AEGDVQRLKLLNGSSS-----KVSELEQKLKRGD-EEAKK 1023
Cdd:COG4942    83 --------AELAELEKEIAELRAELEAQKEELAEllralyRLGRQPPLALLLSPEDfldavRRLQYLKYLAPARrEQAEE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1024 LNSKLKDLEDKVKKQEAQLKlgetSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKS 1103
Cdd:COG4942   155 LRADLAELAALRAELEAERA----ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230

                         250
                  ....*....|....*..
gi 161076750 1104 SLEKEIKDLKTKASKSD 1120
Cdd:COG4942   231 RLEAEAAAAAERTPAAG 247
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 763-1142 3.48e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.39  E-value: 3.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  763 ELRILLELNEQE-----ASILRLKVEDLEKENAESKKYVRELQAKLRQdssngskssllslgtsssaAEKKVKTLNEELV 837
Cdd:NF033838  103 ELNVLKEKSEAEltsktKKELDAAFEQFKKDTLEPGKKVAEATKKVEE-------------------AEKKAKDQKEEDR 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  838 QLRRTLTEKeqtvdslknqlskldTLETE-NDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTaRLKRMQ 916
Cdd:NF033838  164 RNYPTNTYK---------------TLELEiAESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKAEAT-RLEKIK 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  917 LEAEDKlpPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSG------TDQLKALQSAKGALEEDL----RKCKQK 986
Cdd:NF033838  228 TDREKA--EEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGepatpdKKENDAKSSDSSVGEETLpspsLKPEKK 305

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  987 LSLAEgdvqrlkllngssSKVSELEQKLKRGDEEA---------KKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSK 1057
Cdd:NF033838  306 VAEAE-------------KKVEEAKKKAKDQKEEDrrnyptntyKTLELEIAESDVKVKEAELELVKEEAKEPRNEEKIK 372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1058 REKEKLSS-------LE------KDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQV 1124
Cdd:NF033838  373 QAKAKVESkkaeatrLEkiktdrKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPADQQA 452

                         410
                  ....*....|....*....
gi 161076750 1125 Q-DLKKQVEEVQASLSAEQ 1142
Cdd:NF033838  453 EeDYARRSEEEYNRLTQQQ 471
PTZ00121 PTZ00121
MAEBL; Provisional
 1153-1666 3.73e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 3.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1153 EKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIE---RTDMARKLSEAQKRIADLQAKALKTV-NGNGAEYER 1228
Cdd:PTZ00121 1091 EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEearKAEDARKAEEARKAEDAKRVEIARKAeDARKAEEAR 1170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1229 TVLKNKLAEKEHEYERLRRENEMNidlvfqlrkdnddlngKLSDYNRIEQAQSSLN---GHGARREAEIRELKEQLQSTE 1305
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEVRKAEELR----------------KAEDARKAEAARKAEEerkAEEARKAEDAKKAEAVKKAEE 1234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1306 LQMKSEVAtvrlRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKI 1385
Cdd:PTZ00121 1235 AKKDAEEA----KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1386 AYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEeervigsgSTKLPGMKTKLELSWQKEREDQ 1465
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE--------AAEEKAEAAEKKKEEAKKKADA 1382

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1466 QRLLQETSTLARDLRQTLFEVERERD--KERLESKRKLDQIKRATEE--EMEEGRKKiAELQCDLLELRDVHAKLRTSNE 1541
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKADelKKAAAAKKKADEAKKKAEEkkKADEAKKK-AEEAKKADEAKKKAEEAKKAEE 1461

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1542 KLRRERERYEKELIKRRMEADggdRKVGALLQTVDELVKIAPDLKIVGSGGSARSSSSSGYDKNLRPEQPNVRRSRSPSP 1621
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEA---KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 161076750 1622 TLSSSQITSvlARLAEASEELRKFQRVNEDEQERSRMRRSN--LRRA 1666
Cdd:PTZ00121 1539 AKKAEEKKK--ADELKKAEELKKAEEKKKAEEAKKAEEDKNmaLRKA 1583
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
357-476 3.76e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  357 ELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELR 436
Cdd:COG4717   396 EYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL 475

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 161076750  437 RKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRD 476
Cdd:COG4717   476 QELEELKAELRELAEEWAALKLALELLEEAREEYREERLP 515
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1105-1531 4.61e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1105 LEKEIKDLKTKASKSDSKQVQDLKKQVEEVQAsLSAEQKRYEDLNNHWEKLSEEtilmRAQLTTEKQSLQAELNASKQKI 1184
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKE-AEEKEEEYAELQEELEELEEE----LEELEAELEELREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1185 AEMDTIRiERTDMARKLSEAQKRIADLQAKaLKTVNGNGAEYERtvLKNKLAEKEHEYERLRRENEMnidlvfqlrKDND 1264
Cdd:COG4717   126 QLLPLYQ-ELEALEAELAELPERLEELEER-LEELRELEEELEE--LEAELAELQEELEELLEQLSL---------ATEE 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1265 DLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDR 1344
Cdd:COG4717   193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLI 272

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1345 DAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIghLEDQLVESRLESSKIKTELVSERSANEiKI 1424
Cdd:COG4717   273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEE--LEELLAALGLPPDLSPEELLELLDRIE-EL 349

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1425 SEMQSKLNEFEEERVIGSGSTKL------PGMKTKLEL-SWQKEREDQQRLLQETSTLARDLRQTLFEVERE---RDKER 1494
Cdd:COG4717   350 QELLREAEELEEELQLEELEQEIaallaeAGVEDEEELrAALEQAEEYQELKEELEELEEQLEELLGELEELleaLDEEE 429

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 161076750 1495 LESK-RKLDQIKRATEEEMEEGRKKIAELQCDLLELRD 1531
Cdd:COG4717   430 LEEElEELEEELEELEEELEELREELAELEAELEQLEE 467
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 404-1128 5.12e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 5.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   404 EMKEQLDRVTEDKRKLNLRMKELENKGSESE-LRRKLQAAEQICEELMEENQSAK------KEILNLQAEMDEVQDTFRD 476
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENEkVSLKLEEEIQENKDLIKENNATRhlcnllKETCARSAEKTKKYEYERE 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   477 DEVKAKTSLQKDLEK----------ATKNCRI-LSFKLKKSDRKIETLEQERQSsfnaELSNKIKKLEEELRFSNELTRK 545
Cdd:pfam05483  180 ETRQVYMDLNNNIEKmilafeelrvQAENARLeMHFKLKEDHEKIQHLEEEYKK----EINDKEKQVSLLLIQITEKENK 255

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   546 LQaEAEELRNPGKKKAPMLgvlgkstSADAKFTRESLTRggSQEDPQHLQRELQD-------SIERETDLKDQLKFAEEE 618
Cdd:pfam05483  256 MK-DLTFLLEESRDKANQL-------EEKTKLQDENLKE--LIEKKDHLTKELEDikmslqrSMSTQKALEEDLQIATKT 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   619 LQRLRDRERKRVRFSCGTQTEVPLEVVAFprgTQTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPF 698
Cdd:pfam05483  326 ICQLTEEKEAQMEELNKAKAAHSFVVTEF---EATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNN 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   699 AGLFPPSSSSRVGQSGSLLFPSAishvllsgagrklsptpHPHRLAPEVHADRDegisdeddpaELRILLELNEQEASIL 778
Cdd:pfam05483  403 KEVELEELKKILAEDEKLLDEKK-----------------QFEKIAEELKGKEQ----------ELIFLLQAREKEIHDL 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   779 RLKVEDLEKENAESKKYVRELQAKLRQDssngsksslLSLGTSSSAAEKKVKTLNEELVQlrrtltEKEQTVDSLKNQLS 858
Cdd:pfam05483  456 EIQLTAIKTSEEHYLKEVEDLKTELEKE---------KLKNIELTAHCDKLLLENKELTQ------EASDMTLELKKHQE 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   859 KLDTLETENDKLAKENKRL----LALRKASEKTGEvDQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDL 934
Cdd:pfam05483  521 DIINCKKQEERMLKQIENLeekeMNLRDELESVRE-EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNL 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   935 TPKSHLK-KWVEELEDEISEMRVMlSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQR-LKLLNGSSSKVSELEQ 1012
Cdd:pfam05483  600 KKQIENKnKNIEELHQENKALKKK-GSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKeIEDKKISEEKLLEEVE 678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1013 KLKRGDEEAKKLNsklKDLEDKVKKQEAQL-KLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAEL 1091
Cdd:pfam05483  679 KAKAIADEAVKLQ---KEIDKRCQHKIAEMvALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAEL 755

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 161076750  1092 LsakksAEKSKSSLEKEIKDLKTKASKSDSKQVQDLK 1128
Cdd:pfam05483  756 L-----SLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 765-1328 5.21e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 5.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   765 RILLELNEQEASI--LRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKkvkTLNEELVQLRRT 842
Cdd:TIGR00618  311 RIHTELQSKMRSRakLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH---TLTQHIHTLQQQ 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   843 LTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKRMQLEAEDK 922
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   923 LPPRTAKRVNdltpkshlKKWVEELEDEIsemrvmlsssGTDQLKALQSakgaLEEDLRKCKQKLSLAEGDVQRLKLLNG 1002
Cdd:TIGR00618  468 LKEREQQLQT--------KEQIHLQETRK----------KAVVLARLLE----LQEEPCPLCGSCIHPNPARQDIDNPGP 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1003 SSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEK---------DMEKQ 1073
Cdd:TIGR00618  526 LTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNitvrlqdltEKLSE 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1074 AK---------EKEKLEAKISQLD--AELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQ-VEEVQASLSAE 1141
Cdd:TIGR00618  606 AEdmlaceqhaLLRKLQPEQDLQDvrLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKElLASRQLALQKM 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1142 QKRYEDLNNHWEKLSEETILMRAQLTTEK------QSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQkriadLQAKA 1215
Cdd:TIGR00618  686 QSEKEQLTYWKEMLAQCQTLLRELETHIEeydrefNEIENASSSLGSDLAAREDALNQSLKELMHQARTV-----LKART 760

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1216 LKTVNGNGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQL-----RKDNDDLNGKLSDYNRIEQAQSSLNGHGARR 1290
Cdd:TIGR00618  761 EAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLeaeigQEIPSDEDILNLQCETLVQEEEQFLSRLEEK 840

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 161076750  1291 EAEIRELKEQLQSTE--LQMKSEVATVRLRYEQQVKNLSG 1328
Cdd:TIGR00618  841 SATLGEITHQLLKYEecSKQLAQLTQEQAKIIQLSDKLNG 880
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1156-1349 6.08e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 6.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1156 SEETILMRAQLTTEKQSLQAELNASKQKIAEmdtIRIER--TDMARKLSEAQKRIADLQAkalktvngngaeyERTVLKN 1233
Cdd:COG3206   170 REEARKALEFLEEQLPELRKELEEAEAALEE---FRQKNglVDLSEEAKLLLQQLSELES-------------QLAEARA 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1234 KLAEKEHEYERLRRENEMNIDLVFQLRkDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVA 1313
Cdd:COG3206   234 ELAEAEARLAALRAQLGSGPDALPELL-QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 161076750 1314 TVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQ 1349
Cdd:COG3206   313 RILASLEAELEALQAREASLQAQLAQLEARLAELPE 348
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 347-629 6.55e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.96  E-value: 6.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   347 MQEQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLdrVTEDKRKLNLRMKEL 426
Cdd:TIGR00618  384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAA--ITCTAQCEKLEKIHL 461

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   427 -ENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLqkDLEKATKNCRILSFKLKK 505
Cdd:TIGR00618  462 qESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID--NPGPLTRRMQRGEQTYAQ 539

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   506 SDRKIETLEQERQSSFN--AELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESLT 583
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKqrASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLR 619

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 161076750   584 RGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKR 629
Cdd:TIGR00618  620 KLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAL 665
PLN02939 PLN02939
transferase, transferring glycosyl groups
 834-1076 7.00e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.89  E-value: 7.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  834 EELVQLRRTLTEKEQTVDSLKNQ-LSKLDTLETENDKLAKENKRLlalrkaSEKTGEVDQKMKESlAQAQRERDELTARL 912
Cdd:PLN02939  131 EDLVGMIQNAEKNILLLNQARLQaLEDLEKILTEKEALQGKINIL------EMRLSETDARIKLA-AQEKIHVEILEEQL 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  913 KRMQLEAedkLPPRTAKRVNDLTPKSHLKKWVEE---LEDEISEMRVMLSS-SGTDQ-LKALQSAKGALEEDLRKCKQKL 987
Cdd:PLN02939  204 EKLRNEL---LIRGATEGLCVHSLSKELDVLKEEnmlLKDDIQFLKAELIEvAETEErVFKLEKERSLLDASLRELESKF 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  988 SLAEGDVQRLKLLNGSS--SKVSELEQKLKRGDEEAKKLNSKL---KDLEDKVKKQEAQLKLGETSKstwESQSKRE--K 1060
Cdd:PLN02939  281 IVAQEDVSKLSPLQYDCwwEKVENLQDLLDRATNQVEKAALVLdqnQDLRDKVDKLEASLKEANVSK---FSSYKVEllQ 357

                         250
                  ....*....|....*.
gi 161076750 1061 EKLSSLEKDMEKQAKE 1076
Cdd:PLN02939  358 QKLKLLEERLQASDHE 373
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
348-548 7.12e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 7.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  348 QEQMKALKLELETMKTRAEKAEREKSDI-----LLRRLASMDTASNRTAAsealnLQQKLNEMKEQLDRVTEDKRKLnlr 422
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALqerreALQRLAEYSWDEIDVAS-----AEREIAELEAELERLDASSDDL--- 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  423 mKELENKgsESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKatkncrilsfk 502
Cdd:COG4913   688 -AALEEQ--LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----------- 753

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 161076750  503 lkksdRKIETLEQERQSSFNAELSNKIKKLEEEL-RFSNELTRKLQA 548
Cdd:COG4913   754 -----RFAAALGDAVERELRENLEERIDALRARLnRAEEELERAMRA 795
LCD1 pfam09798
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. ...
 1479-1558 8.14e-04

DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. In Schizosaccharomyces pombe this protein is called Rad26 and in Saccharomyces cerevisiae it is called LCD1.


Pssm-ID: 462906  Cd Length: 615  Bit Score: 44.23  E-value: 8.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1479 LRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCD----LLELRDVHAKLRTSNEKLRRERERYEKEL 1554
Cdd:pfam09798    2 LRDKLELLQQEKEKELEKLKNSYEELKSSHEEELEKLKQEVQKLEDEkkflLNELRSLSATSPASSQSHETDTDDSSSVS 81


                   ....
gi 161076750  1555 IKRR 1558
Cdd:pfam09798   82 LKKR 85
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
347-624 8.32e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 8.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  347 MQEQMKALKLELETMKTRAEKAEREKsdillRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKEL 426
Cdd:PRK03918  343 LKKKLKELEKRLEELEERHELYEEAK-----AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGEL 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  427 ENKGSESELR-RKLQAAEQIC------------EELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKD----- 488
Cdd:PRK03918  418 KKEIKELKKAiEELKKAKGKCpvcgrelteehrKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKEselik 497

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  489 LEKATKNCRILSFKLKKSDrkIETLEQ-----ERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPM 563
Cdd:PRK03918  498 LKELAEQLKELEEKLKKYN--LEELEKkaeeyEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL 575

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161076750  564 LGVLGKSTSADAKFTRESLtrgGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRD 624
Cdd:PRK03918  576 LKELEELGFESVEELEERL---KELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633
mukB PRK04863
chromosome partition protein MukB;
829-1087 9.60e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 9.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  829 VKTLNEELVQLRRTLTEKEQTVDSLKNQLS----KLDTLETendKLAKENKRLLALRKASEKTGEVD---QKMKESLAQA 901
Cdd:PRK04863  371 VEEADEQQEENEARAEAAEEEVDELKSQLAdyqqALDVQQT---RAIQYQQAVQALERAKQLCGLPDltaDNAEDWLEEF 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  902 QRERDELTARLkrmqLEAEDKLPPRTA------------KRVNDLTPKSHLKKWVEELEDEISEMRVMLsssgtDQLKAL 969
Cdd:PRK04863  448 QAKEQEATEEL----LSLEQKLSVAQAahsqfeqayqlvRKIAGEVSRSEAWDVARELLRRLREQRHLA-----EQLQQL 518

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  970 QSAKGALEEDLRK----------CKQKLSLAEGDVQRLK-LLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKK- 1037
Cdd:PRK04863  519 RMRLSELEQRLRQqqraerllaeFCKRLGKNLDDEDELEqLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRl 598

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161076750 1038 ----------QEAQLKLGETSKSTWES--------QSKREKEKLSSLEKDmeKQAKEKEKLEAKISQL 1087
Cdd:PRK04863  599 aarapawlaaQDALARLREQSGEEFEDsqdvteymQQLLERERELTVERD--ELAARKQALDEEIERL 664
PTZ00121 PTZ00121
MAEBL; Provisional
 182-628 1.20e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  182 AERVRKMNLLKKQRSLNSRENSRERSVPRREEESESTATPTPVvpDRPERSKSGTSLNQLAQAEQKRAALPPKKVAVAST 261
Cdd:PTZ00121 1130 AEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA--EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARK 1207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  262 TTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVR-----RKEADSVASKEIKRQTVPAASISHSNSTSSTAS 336
Cdd:PTZ00121 1208 AEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERnneeiRKFEEARMAHFARRQAAIKAEEARKADELKKAE 1287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  337 TASKSQDTNGMQEQMKALKL--------ELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQ 408
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAkkkaeeakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  409 LD--RVTEDKRKLNLRMKELENKGSESELRRKLQAAEQICEELmEENQSAKKEILNLQAEMDEVQdtfRDDEVKAKTSLQ 486
Cdd:PTZ00121 1368 AAekKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL-KKAAAAKKKADEAKKKAEEKK---KADEAKKKAEEA 1443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  487 KDLEKATKNCrilsfklkKSDRKIETLEQERQSSFNAElsnKIKKLEEELRFSNELTRKLQaEAEELRNPGKKKAPMLGV 566
Cdd:PTZ00121 1444 KKADEAKKKA--------EEAKKAEEAKKKAEEAKKAD---EAKKKAEEAKKADEAKKKAE-EAKKKADEAKKAAEAKKK 1511

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161076750  567 LGKSTSADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEEL---QRLRDRERK 628
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKkaeEAKKAEEDK 1576
PRK12704 PRK12704
phosphodiesterase; Provisional
 956-1090 1.29e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  956 VMLSSSGTDQLKALQSAKGALEEDLRKC----KQKLSLAEGDVQRLKllngssskvSELEQKLKRGDEEAKKLNSKLKDL 1031
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEAKRILEEAKKEAeaikKEALLEAKEEIHKLR---------NEFEKELRERRNELQKLEKRLLQK 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1032 EDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEK-QAKEKEKLEaKISQLDAE 1090
Cdd:PRK12704   95 EENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEElIEEQLQELE-RISGLTAE 153
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 375-625 1.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  375 ILLRRLASMDTASNRTAASEALN-LQQKLNEMKEQLDRVTEDKRKLNLRMKELENKgsESELRRKLQAAEQICEELMEEN 453
Cdd:COG4942     8 ALLLALAAAAQADAAAEAEAELEqLQQEIAELEKELAALKKEEKALLKQLAALERR--IAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  454 QSAKKEILNLQAEMDEVQDTF-----------RDDEVKAKTSlQKDLEKATKNCRILSFKLKKSDRKIETLEQERQssfn 522
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELaellralyrlgRQPPLALLLS-PEDFLDAVRRLQYLKYLAPARREQAEELRADLA---- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  523 aELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADakftresltrggsqedpqhlQRELQDSI 602
Cdd:COG4942   161 -ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL--------------------AAELAELQ 219

                         250       260
                  ....*....|....*....|...
gi 161076750  603 ERETDLKDQLKFAEEELQRLRDR 625
Cdd:COG4942   220 QEAEELEALIARLEAEAAAAAER 242
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
348-554 1.63e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  348 QEQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELE 427
Cdd:COG3206   181 EEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  428 NKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSfklkksd 507
Cdd:COG3206   261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQ------- 333

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 161076750  508 RKIETLEQERQSSfnAELSNKIKKLEEELRFSNELTRKLQAEAEELR 554
Cdd:COG3206   334 AQLAQLEARLAEL--PELEAELRRLEREVEVARELYESLLQRLEEAR 378
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1039-1214 1.71e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1039 EAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaekskSSLEKEIKDLKTKAsk 1118
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI-----------DKLQAEIAEAEAEI-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1119 sdSKQVQDLKKQVEEVQAS----------LSAEQkrYEDLNNHWEKLS----------EETILMRAQLTTEKQSLQAELN 1178
Cdd:COG3883    82 --EERREELGERARALYRSggsvsyldvlLGSES--FSDFLDRLSALSkiadadadllEELKADKAELEAKKAELEAKLA 157

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 161076750 1179 ASKQKIAEMDTiriERTDMARKLSEAQKRIADLQAK 1214
Cdd:COG3883   158 ELEALKAELEA---AKAELEAQQAEQEALLAQLSAE 190
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 347-550 1.81e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 43.38  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  347 MQEQMKALKLeLETMKTRAEKAEREKSDILLRRLASMDTASNRtAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKEL 426
Cdd:PRK05771   49 RSLLTKLSEA-LDKLRSYLPKLNPLREEKKKVSVKSLEELIKD-VEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  427 ENKGS-ESEL-----------------RRKLQAAEQICEELMEENQSAKKE-----ILNLQAEMDEVQDTFRDDEVKakt 483
Cdd:PRK05771  127 EPWGNfDLDLslllgfkyvsvfvgtvpEDKLEELKLESDVENVEYISTDKGyvyvvVVVLKELSDEVEEELKKLGFE--- 203

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161076750  484 slqkdlEKATKNCRILSFKLKKSDRKIETLEQERQsSFNAELSNKIKKLEEELRFSNEL--TRKLQAEA 550
Cdd:PRK05771  204 ------RLELEEEGTPSELIREIKEELEEIEKERE-SLLEELKELAKKYLEELLALYEYleIELERAEA 265
COG5022 COG5022
Myosin heavy chain [General function prediction only];
763-1302 1.86e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  763 ELRILLELNEQEASiLRLKVEDLEKENAESKKYVRELqaklrqdssngskssllslgtsssaaekkvKTLNEELVQLRRT 842
Cdd:COG5022   952 KLPELNKLHEVESK-LKETSEEYEDLLKKSTILVREG------------------------------NKANSELKNFKKE 1000

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  843 LTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQrerdELTARLKRMQLEAEDK 922
Cdd:COG5022  1001 LAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENN----QLQARYKALKLRRENS 1076

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  923 LPPRTAKRVNDLTPksHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNg 1002
Cdd:COG5022  1077 LLDDKQLYQLESTE--NLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQ- 1153

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1003 ssskvSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKStweSQSKREKEKLSSLEKdmekqaKEKEKLEA 1082
Cdd:COG5022  1154 -----LELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSS---SEVNDLKNELIALFS------KIFSGWPR 1219

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1083 KISQLDaelLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNnhweklseetilm 1162
Cdd:COG5022  1220 GDKLKK---LISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLP------------- 1283

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1163 raqlttekqslqAELNASKQKIAEMD--TIRIERTDMARKLSEAqkriadlqakalktvngngAEYERTVLKNKLAEKEH 1240
Cdd:COG5022  1284 ------------ATINSLLQYINVGLfnALRTKASSLRWKSATE-------------------VNYNSEELDDWCREFEI 1332

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161076750 1241 EYERLRRENEMNIDLVFQLRKDNddlngkLSDYNRIEQAQSSLNghgarrEAEIRELKEQLQ 1302
Cdd:COG5022  1333 SDVDEELEELIQAVKVLQLLKDD------LNKLDELLDACYSLN------PAEIQNLKSRYD 1382
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
947-1087 1.90e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  947 LEDEISEMRVmlsSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKllngssSKVSELEQKLKRGDEEAKKLNS 1026
Cdd:COG2433   378 IEEALEELIE---KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE------AEVEELEAELEEKDERIERLER 448

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161076750 1027 KLKDLedkvkKQEAQLKLGETSKSTwesqsKREKEkLSSLEKDMEKQAKEKEKLEAKISQL 1087
Cdd:COG2433   449 ELSEA-----RSEERREIRKDREIS-----RLDRE-IERLERELEEERERIEELKRKLERL 498
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
394-624 1.91e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  394 EALN-LQQKLNEMKEQLDRVTEDKR-------KLNLRMKELENKGSE--------SELRRKLQAAEQICEELMEENQSAK 457
Cdd:PRK02224  206 ERLNgLESELAELDEEIERYEEQREqaretrdEADEVLEEHEERREEletleaeiEDLRETIAETEREREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  458 KEILNLQAEMDEVQDT--FRDDEVKAKTSLQKDLEKATKNCRilsfklkksdrkiETLEQERQS--SFNAE---LSNKIK 530
Cdd:PRK02224  286 ERLEELEEERDDLLAEagLDDADAEAVEARREELEDRDEELR-------------DRLEECRVAaqAHNEEaesLREDAD 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  531 KLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGVLGKS-TSADAKFTRESLTRGGSQEDPQHLQRELQDSIERETDLK 609
Cdd:PRK02224  353 DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEiEELRERFGDAPVDLGNAEDFLEELREERDELREREAELE 432

                         250
                  ....*....|....*...
gi 161076750  610 DQLKFAE---EELQRLRD 624
Cdd:PRK02224  433 ATLRTARervEEAEALLE 450
PRK01156 PRK01156
chromosome segregation protein; Provisional
 826-1088 2.03e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.35  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  826 EKKVKTLNEELVQLRRTLTEKE-QTVDSLKNQLSKLDTLETEndkLAKENKRLLALRKASEKTGEVDQKMK----ESLAQ 900
Cdd:PRK01156  489 EIEVKDIDEKIVDLKKRKEYLEsEEINKSINEYNKIESARAD---LEDIKIKINELKDKHDKYEEIKNRYKslklEDLDS 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  901 AQRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHlkkwveELEDEISEMRVMLSSSgtdqlkalqsaKGALEEDL 980
Cdd:PRK01156  566 KRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ------EIEIGFPDDKSYIDKS-----------IREIENEA 628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  981 RKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREK 1060
Cdd:PRK01156  629 NNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILR 708

                         250       260       270
                  ....*....|....*....|....*....|.
gi 161076750 1061 EKLSSLEK---DMEKQAKEKEKLEAKISQLD 1088
Cdd:PRK01156  709 TRINELSDrinDINETLESMKKIKKAIGDLK 739
PRK11281 PRK11281
mechanosensitive channel MscK;
1063-1255 3.75e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 3.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1063 LSSLEKdMEKQAKEKEKLEAKISQLDAELLSAkksaeksksslEKEIKDLKTKASKSDSKQ-----VQDLKKQVEEVQAS 1137
Cdd:PRK11281   69 LALLDK-IDRQKEETEQLKQQLAQAPAKLRQA-----------QAELEALKDDNDEETRETlstlsLRQLESRLAQTLDQ 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1138 LSAEQKRYEDLNNhwEKLSEETILMRAqlttekqslQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALK 1217
Cdd:PRK11281  137 LQNAQNDLAEYNS--QLVSLQTQPERA---------QAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLN 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 161076750 1218 TVNgngaEYERTVLKNK-----LAEKEHEY--ERLRRENEMNIDL 1255
Cdd:PRK11281  206 AQN----DLQRKSLEGNtqlqdLLQKQRDYltARIQRLEHQLQLL 246
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 348-1091 3.76e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   348 QEQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELE 427
Cdd:TIGR00606  360 QEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLG 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   428 nkgseselrRKLQAAEQICEELMEENQSAKKEILNLQAEMDevqDTFRDDEVKAKTslQKDLEKATKNCRILSFKLKKSD 507
Cdd:TIGR00606  440 ---------RTIELKKEILEKKQEELKFVIKELQQLEGSSD---RILELDQELRKA--ERELSKAEKNSLTETLKKEVKS 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   508 RKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELR-NPGKKKAPMLGVLG---KSTSADAKFTRESLT 583
Cdd:TIGR00606  506 LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRkIKSRHSDELTSLLGyfpNKKQLEDWLHSKSKE 585

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   584 RGGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDrerkRVRFSCGTQTE------VPLEVVAFPRGTQTVATV 657
Cdd:TIGR00606  586 INQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYED----KLFDVCGSQDEesdlerLKEEIEKSSKQRAMLAGA 661

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   658 QSDMSTSVENLVTSNVA-------VTQTDFEVPDRNVSIERETMSSPFAGLFPPSSSSRVGQSGSLLFpsAISHVLLSGA 730
Cdd:TIGR00606  662 TAVYSQFITQLTDENQSccpvcqrVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEML--GLAPGRQSII 739

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   731 GRKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNG 810
Cdd:TIGR00606  740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSD 819

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   811 SKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKnqlSKLDTLETENDKLAKENKRLLALRKASEKTGEV 890
Cdd:TIGR00606  820 LDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLK---SKTNELKSEKLQIGTNLQRRQQFEEQLVELSTE 896

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   891 DQKMKESLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQ 970
Cdd:TIGR00606  897 VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKE 976

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750   971 SAKGALEEDLRKCKQKLSLAEGDVqRLKLLNGSSSKVSE--LEQKLKRgdeeaKKLNSKLKDLEDKVKKQEAQlkLGETS 1048
Cdd:TIGR00606  977 TELNTVNAQLEECEKHQEKINEDM-RLMRQDIDTQKIQErwLQDNLTL-----RKRENELKEVEEELKQHLKE--MGQMQ 1048

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 161076750  1049 KSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAEL 1091
Cdd:TIGR00606 1049 VLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKEL 1091
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
397-538 4.14e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 4.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  397 NLQQKLNEMKEQLDRVTEDKRKLNL--RMKELENKGSESELR-RKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDT 473
Cdd:COG4717   106 ELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERlEELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 161076750  474 FRDDEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSFN-AELSNKIKKLEEELRF 538
Cdd:COG4717   186 LSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENeLEAAALEERLKEARLL 251
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1069-1437 5.36e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 5.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1069 DMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYED- 1147
Cdd:PLN02939   43 SSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDg 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1148 ---LNNHWEKL------SEETILM----RAQ-------LTTEKQSLQAELNaskqkIAEMdtiRIERTDMARKLSEAQKR 1207
Cdd:PLN02939  123 eqlSDFQLEDLvgmiqnAEKNILLlnqaRLQaledlekILTEKEALQGKIN-----ILEM---RLSETDARIKLAAQEKI 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1208 IADLQAKALKTVNGNGAEYERTVLKNKLAEKEhEYERLRRENemnidlvFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHG 1287
Cdd:PLN02939  195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSK-ELDVLKEEN-------MLLKDDIQFLKAELIEVAETEERVFKLEKER 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1288 ARREAEIRELKEQLQSTELQMkSEVATvrLRYE---QQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKAN 1364
Cdd:PLN02939  267 SLLDASLRELESKFIVAQEDV-SKLSP--LQYDcwwEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEA 343

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161076750 1365 NTGRQSrgsmhssddddKSKIAYLEQQIghledQLVESRLESSkiKTELVSERSANEIKISEMQSKLNEFEEE 1437
Cdd:PLN02939  344 NVSKFS-----------SYKVELLQQKL-----KLLEERLQAS--DHEIHSYIQLYQESIKEFQDTLSKLKEE 398
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1009-1326 6.63e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.48  E-value: 6.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1009 ELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKStwESQSKREKEKLSSLEKDMEKQakeKEKLEAKISQLD 1088
Cdd:COG5185   232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGEN--AESSKRLNENANNLIKQFENT---KEKIAEYTKSID 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1089 AELLSAKKSAEKSKSSLEKEIKDLKTKASKSdskqvqdLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEETILmrAQLTT 1168
Cdd:COG5185   307 IKKATESLEEQLAAAEAEQELEESKRETETG-------IQNLTAEIEQGQESLTENLEAIKEEIENIVGEVEL--SKSSE 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1169 EKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKT-VNGNGAEYERTVLKNKLAEKEHEYERLRR 1247
Cdd:COG5185   378 ELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRqIEQATSSNEEVSKLLNELISELNKVMREA 457

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161076750 1248 ENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQaqsslnghgaRREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNL 1326
Cdd:COG5185   458 DEESQSRLEEAYDEINRSVRSKKEDLNEELT----------QIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESL 526
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
1123-1248 8.00e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 40.60  E-value: 8.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1123 QVQDLKKQVEEVQASLSAEQKRYEDLNNHW-----EKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMD-TIRIERTD 1196
Cdd:COG3524   178 AVRFAEEEVERAEERLRDAREALLAFRNRNgildpEATAEALLQLIATLEGQLAELEAELAALRSYLSPNSpQVRQLRRR 257

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161076750 1197 MARklseAQKRIADLQAKALKTVNGNG-----AEYERTVLKNKLAEKEHE-----YERLRRE 1248
Cdd:COG3524   258 IAA----LEKQIAAERARLTGASGGDSlasllAEYERLELEREFAEKAYTsalaaLEQARIE 315
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1009-1531 8.05e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.26  E-value: 8.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1009 ELEQKLKRGDEEAKKLNSKlKDLE---DKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDME---KQAKEKEKLEA 1082
Cdd:pfam05557   22 ELEHKRARIELEKKASALK-RQLDresDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEalnKKLNEKESQLA 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1083 KISQLdaellsakksaeksKSSLEKEIKDLKTKASKSDSkQVQDLKKQVEEVQASLSAEQKRYEDLNnhweklseetilm 1162
Cdd:pfam05557  101 DAREV--------------ISCLKNELSELRRQIQRAEL-ELQSTNSELEELQERLDLLKAKASEAE------------- 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1163 raQLTTEKQSLQAELNASKQKIAEMD-TIRIERTDMA--RKLSEAQKRIADLQA--KALKTVNgngaEYERTVLKNK--L 1235
Cdd:pfam05557  153 --QLRQNLEKQQSSLAEAEQRIKELEfEIQSQEQDSEivKNSKSELARIPELEKelERLREHN----KHLNENIENKllL 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1236 AEKEHEYE-RLRRENEMNIDLVfQLRKDNDDLNGKLSDYNRIEQAqsslNGHGARREAEIRELKEQLQSTELQMKSEVAT 1314
Cdd:pfam05557  227 KEEVEDLKrKLEREEKYREEAA-TLELEKEKLEQELQSWVKLAQD----TGLNLRSPEDLSRRIEQLQQREIVLKEENSS 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1315 VrlryEQQVKNLSGELTSMQRQCerfkkdRDAFKQMLEVaQKKIGDLKANNTGRQSRGSMHSSDDDdkskiaYLEQQIGH 1394
Cdd:pfam05557  302 L----TSSARQLEKARRELEQEL------AQYLKKIEDL-NKKLKRHKALVRRLQRRVLLLTKERD------GYRAILES 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  1395 LEDQLVESrlESSKIKTELVSERsanEIKISEMQSKLNEfeeervigsgstklpgMKTKLELswqkeredqqrlLQETST 1474
Cdd:pfam05557  365 YDKELTMS--NYSPQLLERIEEA---EDMTQKMQAHNEE----------------MEAQLSV------------AEEELG 411

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 161076750  1475 LARDLRQTLfevERErdkerLESKRKLDQIKRA--TEEEMEEGRKKIAELQCDLLELRD 1531
Cdd:pfam05557  412 GYKQQAQTL---ERE-----LQALRQQESLADPsySKEEVDSLRRKLETLELERQRLRE 462
mukB PRK04863
chromosome partition protein MukB;
1029-1336 8.08e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1029 KDLEDKVKKQEA-QLKLGETSkstwesqskREKEKLSSLEKDMEKQ----------AKEKEKLEAKISQLDAELLSAKKS 1097
Cdd:PRK04863  293 RELYTSRRQLAAeQYRLVEMA---------RELAELNEAESDLEQDyqaasdhlnlVQTALRQQEKIERYQADLEELEER 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1098 AEKSKSSLE--KEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSE-ETILMRAQLTTEK-QSL 1173
Cdd:PRK04863  364 LEEQNEVVEeaDEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERaKQLCGLPDLTADNaEDW 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1174 QAELNASKQKIAEmdtiriERTDMARKLSEAQKrIADLQAKALKTVNGNGAEYERTVLKNKLAEKEHEYERLRRENEMni 1253
Cdd:PRK04863  444 LEEFQAKEQEATE------ELLSLEQKLSVAQA-AHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQRHLAEQ-- 514

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1254 dlVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARR---EAEIRELKEQLQSTELQMKSEVATVRLRY---EQQVKNLS 1327
Cdd:PRK04863  515 --LQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNlddEDELEQLQEELEARLESLSESVSEARERRmalRQQLEQLQ 592


                  ....*....
gi 161076750 1328 GELTSMQRQ 1336
Cdd:PRK04863  593 ARIQRLAAR 601
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
398-934 8.52e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 8.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  398 LQQKLNEMKEQLDRVTEDKRKLNL-RMKELENKgseselRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQdtfrd 476
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLkELKELEEE------LKEAEEKEEEYAELQEELEELEEELEELEAELEELR----- 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  477 dEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSfnAELSNKIKKLEEELRfsnELTRKLQAEAEELRNP 556
Cdd:COG4717   116 -EELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEEL--RELEEELEELEAELA---ELQEELEELLEQLSLA 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  557 GKKKApmlgvlgkstsADAKFTRESLtrggsQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKRvrfscgt 636
Cdd:COG4717   190 TEEEL-----------QDLAEELEEL-----QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK------- 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  637 QTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRnvsiERETMSSPFAGLFPPSSSSRVGQsgsl 716
Cdd:COG4717   247 EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR----EKASLGKEAEELQALPALEELEE---- 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  717 lfpsAISHVLLSGAGRKLSPTPHPHRLAPEVHADRDEGISD-EDDPAELRILLELNEQEASILRLKVEDLEK--ENAESK 793
Cdd:COG4717   319 ----EELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQA 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  794 KYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKkvkTLNEELVQLRRTLTEKEQTVDSLKNQLSKldtLETENDKLAKE 873
Cdd:COG4717   395 EEYQELKEELEELEEQLEELLGELEELLEALDEE---ELEEELEELEEELEELEEELEELREELAE---LEAELEQLEED 468

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161076750  874 NkrllALRKASEKTGEVDQKMKEsLAQAQRERDELTARLKRMQLEAEDKLPPRTAKRVNDL 934
Cdd:COG4717   469 G----ELAELLQELEELKAELRE-LAEEWAALKLALELLEEAREEYREERLPPVLERASEY 524
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1018-1536 9.12e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 9.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1018 DEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKStwesQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDA-------- 1089
Cdd:PRK02224  198 EKEEKDLHERLNGLESELAELDEEIERYEEQRE----QARETRDEADEVLEEHEERREELETLEAEIEDLREtiaetere 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1090 --ELLSAKKSAEKSKSSLEKEIKDLKTKASKSD------SKQVQDLKKQVEEVQASLSAEQKRYEDLNNHWEKLSEEtIL 1161
Cdd:PRK02224  274 reELAEEVRDLRERLEELEEERDDLLAEAGLDDadaeavEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRED-AD 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1162 MRAQLTTEKQSLQAELNAskqkiaEMDTIRIERTDMARKLSEAQKRIADLQAKAlktvngNGAEYERTVLKNKLAEKEHE 1241
Cdd:PRK02224  353 DLEERAEELREEAAELES------ELEEAREAVEDRREEIEELEEEIEELRERF------GDAPVDLGNAEDFLEELREE 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1242 YERLR-RENEMNIDLvfQLRKDNDDLNGKLSDYNRIEQAQSSLNGHG-ARREAEIRELKEQLQSTELQMKSEVATVRLRY 1319
Cdd:PRK02224  421 RDELReREAELEATL--RTARERVEEAEALLEAGKCPECGQPVEGSPhVETIEEDRERVEELEAELEDLEEEVEEVEERL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1320 EQQVknlsgELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAyleqQIGHLEDQL 1399
Cdd:PRK02224  499 ERAE-----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA----AEAEEEAEE 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1400 VESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEErvIGSGSTKLPGmktklelswQKEREDQQR-LLQETSTLARD 1478
Cdd:PRK02224  570 AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDE--IERLREKREA---------LAELNDERReRLAEKRERKRE 638

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 161076750 1479 LRQTLFE--VERER-DKERLES-KRKLDQIKRATEEEMEEGRKKI----AELQcDLLELRDVHAKL 1536
Cdd:PRK02224  639 LEAEFDEarIEEAReDKERAEEyLEQVEEKLDELREERDDLQAEIgaveNELE-ELEELRERREAL 703
PTZ00121 PTZ00121
MAEBL; Provisional
 182-628 9.57e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 9.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  182 AERVRKMNLLKKQ-RSLNSRENSRERSVPRREEESESTATPTPVVPDRPERSKSGTSLNQLAQAEQKRAALPPKKVAVAS 260
Cdd:PTZ00121 1311 AEEAKKADEAKKKaEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  261 TTTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSV----RRKEADSVASKEIKRQTVPAASISHSNSTSSTAS 336
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKadeaKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  337 TASKSQDTNGMQEQMKALKLELETMKTRAEKA-----EREKSDIL-----LRRLASMDTASNRTAASEALNLQQ--KLNE 404
Cdd:PTZ00121 1471 KADEAKKKAEEAKKADEAKKKAEEAKKKADEAkkaaeAKKKADEAkkaeeAKKADEAKKAEEAKKADEAKKAEEkkKADE 1550

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  405 MKEQLD-RVTEDKRKLNLRMKELENKGSE----SELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEV 479
Cdd:PTZ00121 1551 LKKAEElKKAEEKKKAEEAKKAEEDKNMAlrkaEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  480 KAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAE---------- 549
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakkaeelkkk 1710

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  550 -------AEELRNPGKKKAPMLGVLGKSTSADAKFTRESLTRGGSQEDPQHLQRELQDSI-----ERETDLKDQLKFAEE 617
Cdd:PTZ00121 1711 eaeekkkAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAeeirkEKEAVIEEELDEEDE 1790

                         490
                  ....*....|.
gi 161076750  618 ELQRLRDRERK 628
Cdd:PTZ00121 1791 KRRMEVDKKIK 1801
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
349-526 9.68e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 9.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  349 EQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELEN 428
Cdd:COG4717   344 DRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLE 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  429 KGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQK----DLEKATKNCRILSFKLk 504
Cdd:COG4717   424 ALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKaelrELAEEWAALKLALELL- 502

                         170       180
                  ....*....|....*....|..
gi 161076750  505 ksDRKIETLEQERQSSFNAELS 526
Cdd:COG4717   503 --EEAREEYREERLPPVLERAS 522
PLN02939 PLN02939
transferase, transferring glycosyl groups
 367-553 9.69e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.04  E-value: 9.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  367 KAEREKSDILLRRLASMDtasnRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELRRKLQAAEQIC 446
Cdd:PLN02939  120 KDGEQLSDFQLEDLVGMI----QNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIH 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  447 EELME---------------------------------ENQSAKKEILNLQAEMDEVQDTfrdDEVKAKTSLQKDLEKAT 493
Cdd:PLN02939  196 VEILEeqleklrnellirgateglcvhslskeldvlkeENMLLKDDIQFLKAELIEVAET---EERVFKLEKERSLLDAS 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750  494 knCRILSFKLKKSD---------------RKIETLE--------QERQSSF----NAELSNKIKKLEEELRFSNelTRKL 546
Cdd:PLN02939  273 --LRELESKFIVAQedvsklsplqydcwwEKVENLQdlldratnQVEKAALvldqNQDLRDKVDKLEASLKEAN--VSKF 348


                  ....*..
gi 161076750  547 QAEAEEL 553
Cdd:PLN02939  349 SSYKVEL 355
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1061-1193 9.78e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 9.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161076750 1061 EKLSSLEKDMEKQAKEKEKLEAKISQLDAELlsakksaEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSA 1140
Cdd:PRK00409  523 ASLEELERELEQKAEEAEALLKEAEKLKEEL-------EEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQ 595

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 161076750 1141 EQK-RYEDLNNHweklseETILMRAQLTTEKQSLQAELNASKQKIAEM---DTIRIE 1193
Cdd:PRK00409  596 LQKgGYASVKAH------ELIEARKRLNKANEKKEKKKKKQKEKQEELkvgDEVKYL 646
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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