COG5 family protein similar to Arabidopsis thaliana conserved oligomeric Golgi complex subunit 5 (COG5) which is a component of the conserved oligomeric Golgi complex (COG), and is required for normal Golgi function| COG1/VPS51 family protein similar to Homo sapiens conserved oligomeric Golgi complex subunit 1 (COG1) and Schizosaccharomyces pombe vacuolar protein sorting-associated protein 51 (VPS51)
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst ...
132-914
0e+00
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst complex which is an octomeric complex that mediates the tethering of post-Golgi secretory vesicles to the plasma membrane during exocytosis.
:
Pssm-ID: 464733 Cd Length: 810 Bit Score: 680.24 E-value: 0e+00
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
8-89
6.65e-10
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
:
Pssm-ID: 238337 [Multi-domain] Cd Length: 90 Bit Score: 56.69 E-value: 6.65e-10
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst ...
132-914
0e+00
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst complex which is an octomeric complex that mediates the tethering of post-Golgi secretory vesicles to the plasma membrane during exocytosis.
Pssm-ID: 464733 Cd Length: 810 Bit Score: 680.24 E-value: 0e+00
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
8-89
6.65e-10
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Pssm-ID: 238337 [Multi-domain] Cd Length: 90 Bit Score: 56.69 E-value: 6.65e-10
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
8-91
7.34e-10
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.
Pssm-ID: 460355 [Multi-domain] Cd Length: 84 Bit Score: 56.30 E-value: 7.34e-10
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst ...
132-914
0e+00
Exocyst complex component Sec5; This entry represents the Sec5 component of the exocyst complex which is an octomeric complex that mediates the tethering of post-Golgi secretory vesicles to the plasma membrane during exocytosis.
Pssm-ID: 464733 Cd Length: 810 Bit Score: 680.24 E-value: 0e+00
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
8-89
6.65e-10
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Pssm-ID: 238337 [Multi-domain] Cd Length: 90 Bit Score: 56.69 E-value: 6.65e-10
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
8-91
7.34e-10
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.
Pssm-ID: 460355 [Multi-domain] Cd Length: 84 Bit Score: 56.30 E-value: 7.34e-10
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are ...
8-90
1.49e-09
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Pssm-ID: 238585 Cd Length: 94 Bit Score: 55.78 E-value: 1.49e-09
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as ...
8-90
2.48e-07
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor receptors), as well as, cyclodextrin glycosyltransferase and similar enzymes. Although they are involved in DNA binding in transcription factors, their function in other proteins is unknown. In these transcription factors, IPTs form homo- or heterodimers with the exception of the nuclear factor of activated Tcells (NFAT) transcription factors which are mainly monomers.
Pssm-ID: 238050 [Multi-domain] Cd Length: 89 Bit Score: 49.38 E-value: 2.48e-07
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are ...
8-63
2.63e-03
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Pssm-ID: 238584 Cd Length: 85 Bit Score: 37.59 E-value: 2.63e-03
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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