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Conserved domains on  [gi|1996911450|ref|NP_599232|]
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solute carrier family 12 member 9 [Rattus norvegicus]

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
36-905 7.57e-126

Amino acid permease;


The actual alignment was detected with superfamily member TIGR00930:

Pssm-ID: 459263 [Multi-domain]  Cd Length: 953  Bit Score: 403.71  E-value: 7.57e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPE 115
Cdd:TIGR00930  77 KFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPE 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 116 VGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADvtgSSGIKVLP----QGYGwnllygSLLLGLVGGVCALGAGLYAR 191
Cdd:TIGR00930 157 FGGSIGLIFAFANAVAVAMYVVGFAETVLDLLREN---GSKIMVDPindiRIYG------TVTVVVLLGISFAGMEWENK 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 192 ASFLTFLLVSGSLASVLVsfvavgprnitlaprpGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYaedytTGAMMTFASVF 271
Cdd:TIGR00930 228 AQVLFLVIVLLSILNIFV----------------GTIIPAFDKPAKGFFGLGNEIFSENFIPGI-----PGPEGGFFSLF 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 272 AVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYIL--LFF----------------------LSSFTcDRA 327
Cdd:TIGR00930 287 GIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGsvVLFgacvvrdatgdkndtlvtnctsAACFS-ECA 365
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 328 LLQGDYGFFRD------ISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYS 401
Cdd:TIGR00930 366 HNTCSYGLMNNlqvmslVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLT 445
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 402 WGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGS 481
Cdd:TIGR00930 446 AFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVA 525
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 482 LLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKG-GLY 560
Cdd:TIGR00930 526 MVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGkGLM 605
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 561 VLGHVTLGD-LDSLP-SDPVQPQYGAWLslvDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDD---A 635
Cdd:TIGR00930 606 ICGSVIQGPrLECVKeAQAAEAKIQTWL---EKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDwrqA 682
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 636 PPQDhfltdpafsepaegtreggspalstlfppprapgspralsPQDYVATVADALKMNKNVVLARACGALPPERLSRG- 714
Cdd:TIGR00930 683 EPRA----------------------------------------WETYIGIIHDAFDAHLAVVVVRNSEGLPISVLQVQe 722
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 715 --------------SGSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLF-----LLQMATILSMVPAWHSARLRIFlCLGPR 775
Cdd:TIGR00930 723 elendcsedsielnDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVddgglTLLLPYLLTTKKVWKKCKIRIF-VGAQK 801
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 776 EAPGAAEGR-LRALLSQLRIRAEVQEVVW-GEGAEAGEPEEEEGDFVNGGRGDEEAEALACSANALVRA----------Q 843
Cdd:TIGR00930 802 DDRSEQEKKdMATLLYKFRIDAEVIVVLMdINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDPKMTWTkpwkitdaelQ 881
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1996911450 844 QGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLIHG 905
Cdd:TIGR00930 882 SNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRG 943
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
36-905 7.57e-126

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 403.71  E-value: 7.57e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPE 115
Cdd:TIGR00930  77 KFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPE 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 116 VGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADvtgSSGIKVLP----QGYGwnllygSLLLGLVGGVCALGAGLYAR 191
Cdd:TIGR00930 157 FGGSIGLIFAFANAVAVAMYVVGFAETVLDLLREN---GSKIMVDPindiRIYG------TVTVVVLLGISFAGMEWENK 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 192 ASFLTFLLVSGSLASVLVsfvavgprnitlaprpGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYaedytTGAMMTFASVF 271
Cdd:TIGR00930 228 AQVLFLVIVLLSILNIFV----------------GTIIPAFDKPAKGFFGLGNEIFSENFIPGI-----PGPEGGFFSLF 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 272 AVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYIL--LFF----------------------LSSFTcDRA 327
Cdd:TIGR00930 287 GIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGsvVLFgacvvrdatgdkndtlvtnctsAACFS-ECA 365
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 328 LLQGDYGFFRD------ISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYS 401
Cdd:TIGR00930 366 HNTCSYGLMNNlqvmslVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLT 445
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 402 WGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGS 481
Cdd:TIGR00930 446 AFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVA 525
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 482 LLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKG-GLY 560
Cdd:TIGR00930 526 MVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGkGLM 605
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 561 VLGHVTLGD-LDSLP-SDPVQPQYGAWLslvDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDD---A 635
Cdd:TIGR00930 606 ICGSVIQGPrLECVKeAQAAEAKIQTWL---EKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDwrqA 682
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 636 PPQDhfltdpafsepaegtreggspalstlfppprapgspralsPQDYVATVADALKMNKNVVLARACGALPPERLSRG- 714
Cdd:TIGR00930 683 EPRA----------------------------------------WETYIGIIHDAFDAHLAVVVVRNSEGLPISVLQVQe 722
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 715 --------------SGSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLF-----LLQMATILSMVPAWHSARLRIFlCLGPR 775
Cdd:TIGR00930 723 elendcsedsielnDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVddgglTLLLPYLLTTKKVWKKCKIRIF-VGAQK 801
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 776 EAPGAAEGR-LRALLSQLRIRAEVQEVVW-GEGAEAGEPEEEEGDFVNGGRGDEEAEALACSANALVRA----------Q 843
Cdd:TIGR00930 802 DDRSEQEKKdMATLLYKFRIDAEVIVVLMdINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDPKMTWTkpwkitdaelQ 881
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1996911450 844 QGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLIHG 905
Cdd:TIGR00930 882 SNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRG 943
AA_permease pfam00324
Amino acid permease;
42-535 8.60e-83

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 274.58  E-value: 8.60e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  42 GVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVrGGGAYFMISRTLGPEVGGSIG 121
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 122 LM------FYLANVCGCAVSLLGLVESILDVFGADVTGSSGIKVLpqgygwnllygslllglvGGVCALGAGLYARASFL 195
Cdd:pfam00324  80 WNywlswiTVLALELTAASILIQFWELVPDIPYLWVWGAVFLVLL------------------TIINLVGVKWYGEAEFW 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 196 TFLLVSGSLASVLVSFVAvgprnitlaprPGTNGSSVPPRHGHFTGFNGStlKDNLGAGYAEDyttgammtFASVFAVLF 275
Cdd:pfam00324 142 FALIKIIAIIGFIIVGII-----------LLSGGNPNDGAIFRYLGDNGG--KNNFPPGFGKG--------FISVFVIAF 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 276 NGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDR------------ALLQGDYGFFRDISLWP 343
Cdd:pfam00324 201 FAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpgllndsasaASPFVIFFKFLGISGLA 280
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 344 PLVLIGIYATALSASMSSLIGASRILHALAQDDLFGvilAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTlaAVVTV 423
Cdd:pfam00324 281 PLINAVILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKRGVPLRAILVSMVISLLALLLASLNP--AIVFN 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 424 FYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGY 503
Cdd:pfam00324 356 FLLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGA 435
                         490       500       510
                  ....*....|....*....|....*....|..
gi 1996911450 504 VSQALLFHQVRKYLLRLDVRKEHVKFWRPQLL 535
Cdd:pfam00324 436 GSFAAAYLIVLLFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
35-477 4.95e-30

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 124.24  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  35 RKLSTFlGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAyVILALTVLSVCAIATNgAVRGGGAYFMISRTLGP 114
Cdd:COG0531    11 RKLGLF-DLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAG-LLALLVALSYAELASA-FPRAGGAYTYARRALGP 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 115 EVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGAdvtgssgikvlpqgyGWNLLYGSLLLGLVGGVCALGAGLYARA-S 193
Cdd:COG0531    88 LLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPA---------------GGSVLIALVLILLLTLLNLRGVKESAKVnN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 194 FLTFLLVSGSLASVLVSFVAVGPrnitlaprpgtngssvpprhGHFTGFNGstlkdnlgagyaedyTTGAMMTFASVFAV 273
Cdd:COG0531   153 ILTVLKLLVLLLFIVVGLFAFDP--------------------ANFTPFLP---------------AGGGLSGVLAALAL 197
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 274 LFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDI------SLWPPLVL 347
Cdd:COG0531   198 AFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGAPLADAaeavfgPWGAILIA 277
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 348 IGIYATALSASMSSLIGASRILHALAQDDLFGVILapAKVVSGGGNPWGAVLYSWGLVQLVLLAGK--LNTLAAVVTVFY 425
Cdd:COG0531   278 LGALLSLLGALNASILGASRLLYAMARDGLLPKVF--AKVHPRFGTPVNAILLTGVIALLLLLLGAasFTALASLASVGV 355
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1996911450 426 LVAYAAVDLSCLSLEWaSAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGA 477
Cdd:COG0531   356 LLAYLLVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGA 406
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
36-905 7.57e-126

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 403.71  E-value: 7.57e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPE 115
Cdd:TIGR00930  77 KFGWVMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPE 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 116 VGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADvtgSSGIKVLP----QGYGwnllygSLLLGLVGGVCALGAGLYAR 191
Cdd:TIGR00930 157 FGGSIGLIFAFANAVAVAMYVVGFAETVLDLLREN---GSKIMVDPindiRIYG------TVTVVVLLGISFAGMEWENK 227
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 192 ASFLTFLLVSGSLASVLVsfvavgprnitlaprpGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYaedytTGAMMTFASVF 271
Cdd:TIGR00930 228 AQVLFLVIVLLSILNIFV----------------GTIIPAFDKPAKGFFGLGNEIFSENFIPGI-----PGPEGGFFSLF 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 272 AVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYIL--LFF----------------------LSSFTcDRA 327
Cdd:TIGR00930 287 GIFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGsvVLFgacvvrdatgdkndtlvtnctsAACFS-ECA 365
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 328 LLQGDYGFFRD------ISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYS 401
Cdd:TIGR00930 366 HNTCSYGLMNNlqvmslVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLT 445
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 402 WGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGS 481
Cdd:TIGR00930 446 AFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVA 525
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 482 LLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKG-GLY 560
Cdd:TIGR00930 526 MVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGkGLM 605
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 561 VLGHVTLGD-LDSLP-SDPVQPQYGAWLslvDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDD---A 635
Cdd:TIGR00930 606 ICGSVIQGPrLECVKeAQAAEAKIQTWL---EKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDwrqA 682
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 636 PPQDhfltdpafsepaegtreggspalstlfppprapgspralsPQDYVATVADALKMNKNVVLARACGALPPERLSRG- 714
Cdd:TIGR00930 683 EPRA----------------------------------------WETYIGIIHDAFDAHLAVVVVRNSEGLPISVLQVQe 722
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 715 --------------SGSSAQLHHVDVWPLNLLRPRGGPGYVDVCGLF-----LLQMATILSMVPAWHSARLRIFlCLGPR 775
Cdd:TIGR00930 723 elendcsedsielnDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVddgglTLLLPYLLTTKKVWKKCKIRIF-VGAQK 801
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 776 EAPGAAEGR-LRALLSQLRIRAEVQEVVW-GEGAEAGEPEEEEGDFVNGGRGDEEAEALACSANALVRA----------Q 843
Cdd:TIGR00930 802 DDRSEQEKKdMATLLYKFRIDAEVIVVLMdINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDPKMTWTkpwkitdaelQ 881
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1996911450 844 QGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDLGPTLLIHG 905
Cdd:TIGR00930 882 SNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRG 943
AA_permease pfam00324
Amino acid permease;
42-535 8.60e-83

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 274.58  E-value: 8.60e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  42 GVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVrGGGAYFMISRTLGPEVGGSIG 121
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 122 LM------FYLANVCGCAVSLLGLVESILDVFGADVTGSSGIKVLpqgygwnllygslllglvGGVCALGAGLYARASFL 195
Cdd:pfam00324  80 WNywlswiTVLALELTAASILIQFWELVPDIPYLWVWGAVFLVLL------------------TIINLVGVKWYGEAEFW 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 196 TFLLVSGSLASVLVSFVAvgprnitlaprPGTNGSSVPPRHGHFTGFNGStlKDNLGAGYAEDyttgammtFASVFAVLF 275
Cdd:pfam00324 142 FALIKIIAIIGFIIVGII-----------LLSGGNPNDGAIFRYLGDNGG--KNNFPPGFGKG--------FISVFVIAF 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 276 NGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDR------------ALLQGDYGFFRDISLWP 343
Cdd:pfam00324 201 FAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpgllndsasaASPFVIFFKFLGISGLA 280
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 344 PLVLIGIYATALSASMSSLIGASRILHALAQDDLFGvilAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTlaAVVTV 423
Cdd:pfam00324 281 PLINAVILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKRGVPLRAILVSMVISLLALLLASLNP--AIVFN 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 424 FYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGPSSWGY 503
Cdd:pfam00324 356 FLLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGA 435
                         490       500       510
                  ....*....|....*....|....*....|..
gi 1996911450 504 VSQALLFHQVRKYLLRLDVRKEHVKFWRPQLL 535
Cdd:pfam00324 436 GSFAAAYLIVLLFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
35-477 4.95e-30

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 124.24  E-value: 4.95e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  35 RKLSTFlGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAyVILALTVLSVCAIATNgAVRGGGAYFMISRTLGP 114
Cdd:COG0531    11 RKLGLF-DLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAG-LLALLVALSYAELASA-FPRAGGAYTYARRALGP 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 115 EVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGAdvtgssgikvlpqgyGWNLLYGSLLLGLVGGVCALGAGLYARA-S 193
Cdd:COG0531    88 LLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPA---------------GGSVLIALVLILLLTLLNLRGVKESAKVnN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 194 FLTFLLVSGSLASVLVSFVAVGPrnitlaprpgtngssvpprhGHFTGFNGstlkdnlgagyaedyTTGAMMTFASVFAV 273
Cdd:COG0531   153 ILTVLKLLVLLLFIVVGLFAFDP--------------------ANFTPFLP---------------AGGGLSGVLAALAL 197
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 274 LFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDI------SLWPPLVL 347
Cdd:COG0531   198 AFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGAPLADAaeavfgPWGAILIA 277
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 348 IGIYATALSASMSSLIGASRILHALAQDDLFGVILapAKVVSGGGNPWGAVLYSWGLVQLVLLAGK--LNTLAAVVTVFY 425
Cdd:COG0531   278 LGALLSLLGALNASILGASRLLYAMARDGLLPKVF--AKVHPRFGTPVNAILLTGVIALLLLLLGAasFTALASLASVGV 355
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1996911450 426 LVAYAAVDLSCLSLEWaSAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGA 477
Cdd:COG0531   356 LLAYLLVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGA 406
SLC12 pfam03522
Solute carrier family 12;
546-794 5.13e-12

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 68.80  E-value: 5.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 546 PLLRLANQL-KKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLslvDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKP 624
Cdd:pfam03522   3 ALVDFAHLItKNVSLMICGHVVKGRLSQKLRSELQKKAYRWL---RKRKIKAFYALVDGDNLREGAQALLQASGLGKLKP 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 625 NTLVLGFYDD---APPQD-----HFLTDpAF-----------------SE-PAEGTREGGSPALSTLFPPPRAPGSPRAL 678
Cdd:pfam03522  80 NILLMGYKSDwrtCDKEEleeyfNVIHD-AFdlqyavailrlpegldvSHlLQDQDTEELGLGDETNSSYAEQSSEEQST 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 679 SPQDYVATVADALKMNKNVVLARACGALPPERlsRGSGSSAQLHHVDvwPLNLLRPRGGP----------------GYVD 742
Cdd:pfam03522 159 SNSKQDDDKSKLSKKDSNLSLSPDKSTKNPSG--KDSSKSDKLKKKS--PSIILRTASNEkeilnnitqfqkkqkkGTID 234
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1996911450 743 VC------GLFLLqMATILSMVPAWHSARLRIFlCLGPREAPGAAEGR-LRALLSQLRI 794
Cdd:pfam03522 235 VWwlyddgGLTLL-LPYILSTRSKWSDCKLRVF-ALGNRKDELEEEQRnMASLLSKFRI 291
AA_permease_2 pfam13520
Amino acid permease;
47-472 7.73e-08

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 55.78  E-value: 7.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450  47 TVLSMFSIVVFLRIG---FVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAV--RGGGAYFMISRTLGPEVGGSIG 121
Cdd:pfam13520   2 GLLSAFALVIGSVIGsgiFVAPLVASGGPALIVWGWIAAIIFSLAVGLVYAELSSAlpRSGGIYVYLENAFGKFVAFLAG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 122 LMFYLANVCGCAVSLLGLVESILDVFGADVTGSSGIKVLpqgygwnllYGSLLLGLVGGVCALGAGLYARASFLTFLLvs 201
Cdd:pfam13520  82 WSNWFAYVLGLASSASVAASYLLSALGPDLVPTTWLTYG---------IAIAILIIFAIINIRGVRESAKIQNILGIL-- 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 202 gSLASVLVSFVAVGprnitlAPRPGTNGSSVPPRHGHFTGfngstlkdnlgagyaedyTTGAMMTFASVFAVLFnGCTGI 281
Cdd:pfam13520 151 -KLLLPLILIIILG------LVTADGGGFNLLSGEWHTFF------------------PDGWPGVFAGFLGVLW-SFTGF 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 282 MAGANMSGELKDpsRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFfrdISLWPPL------------VLIG 349
Cdd:pfam13520 205 ESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGL---GQVAALLfqavggkwgaiiVVIL 279
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 350 IYATALSASMSSLIGASRILHALAQDdlfGVILAPA--KVVSGGGNPWGAVLYSWGLVQLVLL-----AGKLNTLAAVVT 422
Cdd:pfam13520 280 LALSLLGAVNTAIVGASRLLYALARD---GVLPFSRffAKVNKFGSPIRAIILTAILSLILLLlfllsPAAYNALLSLSA 356
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 1996911450 423 VFYLVAYAAVDLSCLSLEWASaPNFRPTFslFSWHTCLLGVASCLLMMFL 472
Cdd:pfam13520 357 YGYLLSYLLPIIGLLILRKKR-PDLGRIP--GRWPVAIFGILFSLFLIVA 403
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
272-443 2.97e-04

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 44.42  E-value: 2.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 272 AVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDISL--WPP---LV 346
Cdd:TIGR00906 238 ATCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMPYYLLDPDAPFPVAFEYvgWDPakyIV 317
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1996911450 347 LIGIYATALSASMSSLIGASRILHALAQDDLFGVILapAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYL 426
Cdd:TIGR00906 318 AVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWL--AQINSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTL 395
                         170
                  ....*....|....*..
gi 1996911450 427 VAYAAVDLSCLSLEWAS 443
Cdd:TIGR00906 396 LAYSLVAACVLILRYQP 412
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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