proteasome regulatory particle base subunit RPN2 [Encephalitozoon cuniculi GB-M1]
Protein Classification
26S proteasome non-ATPase regulatory subunit 1; 3-phosphoglycerate dehydrogenase family protein( domain architecture ID 11473818)
26S proteasome non-ATPase regulatory subunit 1 (PSMD1), also known as RPN2, is a non-ATPase subunit of the 19S regulatory complex of the 26S proteasome which plays a critical role in the recognition of ubiquitinated protein substrates by the proteasome and is involved in the ATP-dependent unfolding and translocation of these substrates into the proteasome core for degradation| 3-phosphoglycerate dehydrogenase family protein may catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate; also contains 26S proteasome regulatory subunit RPN2 C-terminal domain
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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