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Conserved domains on  [gi|18859703|ref|NP_572731|]
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uncharacterized protein Dmel_CG11696 [Drosophila melanogaster]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10544459)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  22803940|11361095|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-81 2.72e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 462262  Cd Length: 75  Bit Score: 56.70  E-value: 2.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18859703     2 ICRLCLEDAEHGVPIFGQEPpmgqpAHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEIEQFCSMVAEKQRSLHRS 81
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSD-----SEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQEL 75
zf-H2C2_2 pfam13465
Zinc-finger double domain;
521-545 2.35e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.35e-03
                          10        20
                  ....*....|....*....|....*
gi 18859703   521 ALSSHMRYHHSAKRHKCSLCDKEFK 545
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-81 2.72e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 56.70  E-value: 2.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18859703     2 ICRLCLEDAEHGVPIFGQEPpmgqpAHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEIEQFCSMVAEKQRSLHRS 81
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSD-----SEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQEL 75
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-78 1.42e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 51.75  E-value: 1.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18859703      2 ICRLCLEDAEHGVPIFGQEPpmgqpaHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEIEQFCSMVAEKQRSL 78
Cdd:smart00868   1 VCRLCLSESENLVSIFDESS------EASLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-H2C2_2 pfam13465
Zinc-finger double domain;
521-545 2.35e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.35e-03
                          10        20
                  ....*....|....*....|....*
gi 18859703   521 ALSSHMRYHHSAKRHKCSLCDKEFK 545
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Name Accession Description Interval E-value
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-81 2.72e-10

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 56.70  E-value: 2.72e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18859703     2 ICRLCLEDAEHGVPIFGQEPpmgqpAHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEIEQFCSMVAEKQRSLHRS 81
Cdd:pfam07776   1 VCRLCLDESDELIPIFDPSD-----SEKTLAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSFRERCLESQELLQEL 75
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-78 1.42e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 51.75  E-value: 1.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18859703      2 ICRLCLEDAEHGVPIFGQEPpmgqpaHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEIEQFCSMVAEKQRSL 78
Cdd:smart00868   1 VCRLCLSESENLVSIFDESS------EASLAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFRERCRESDELL 71
zf-H2C2_2 pfam13465
Zinc-finger double domain;
521-545 2.35e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.35e-03
                          10        20
                  ....*....|....*....|....*
gi 18859703   521 ALSSHMRYHHSAKRHKCSLCDKEFK 545
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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