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Conserved domains on  [gi|240256454|ref|NP_568884|]
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Undecaprenyl pyrophosphate synthetase family protein [Arabidopsis thaliana]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10087541)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates

CATH:  3.40.1180.10
EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0016094
PubMed:  16900467|12636086|12135472
SCOP:  4003318

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 73-291 9.90e-115

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


:

Pssm-ID: 259850  Cd Length: 219  Bit Score: 329.72  E-value: 9.90e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  73 HVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMPY 152
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 153 LRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAMEK 232
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 240256454 233 ELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:cd00475  161 HLYTA--DLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 73-291 9.90e-115

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 329.72  E-value: 9.90e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  73 HVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMPY 152
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 153 LRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAMEK 232
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 240256454 233 ELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:cd00475  161 HLYTA--DLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
70-291 4.28e-114

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 329.32  E-value: 4.28e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:COG0020   15 LPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLRRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:COG0020   95 LDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDEET 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:COG0020  175 ISRYLYT--ADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDY 234
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 77-291 1.09e-102

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 299.28  E-value: 1.09e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454   77 ILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEK-YLASDMPYLRS 155
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  156 DKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDglIQVEDINEKAMEKELL 235
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKK--LDPEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 240256454  236 TkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:pfam01255 159 T--AGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDY 212
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 70-291 4.31e-88

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 263.28  E-value: 4.31e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14830  22 IPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFLDKF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:PRK14830 102 VPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPEDITEEL 181

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14830 182 ISNYLMTK--GLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDY 241
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 72-291 8.61e-79

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 238.84  E-value: 8.61e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454   72 KHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMP 151
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  152 YLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAME 231
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  232 KELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:TIGR00055 161 KHLYT--ANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDF 218
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 73-291 9.90e-115

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 329.72  E-value: 9.90e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  73 HVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMPY 152
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 153 LRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAMEK 232
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 240256454 233 ELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:cd00475  161 HLYTA--DLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDY 217
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
70-291 4.28e-114

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 329.32  E-value: 4.28e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:COG0020   15 LPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYLRRE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:COG0020   95 LDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPEDIDEET 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:COG0020  175 ISRYLYT--ADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDY 234
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 77-291 1.09e-102

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 299.28  E-value: 1.09e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454   77 ILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEK-YLASDMPYLRS 155
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEeYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  156 DKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDglIQVEDINEKAMEKELL 235
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKK--LDPEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 240256454  236 TkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:pfam01255 159 T--AGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDY 212
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 70-291 4.31e-88

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 263.28  E-value: 4.31e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14830  22 IPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFLDKF 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:PRK14830 102 VPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNPEDITEEL 181

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14830 182 ISNYLMTK--GLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDY 241
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 69-291 2.05e-85

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 256.54  E-value: 2.05e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  69 IMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLAS 148
Cdd:PRK14836  13 NIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKALDR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 149 DMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEK 228
Cdd:PRK14836  93 EVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPDEIDEA 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240256454 229 AMEKELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14836 173 LLAQHLALA--DLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDY 233
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 70-291 2.38e-83

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 251.40  E-value: 2.38e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14831  20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVLRRE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:PRK14831 100 LEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEIDENL 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTKcsEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14831 180 FESELYTA--GIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDY 239
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 72-291 8.61e-79

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 238.84  E-value: 8.61e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454   72 KHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMP 151
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  152 YLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAME 231
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  232 KELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:TIGR00055 161 KHLYT--ANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDF 218
PRK14834 PRK14834
isoprenyl transferase;
71-291 1.28e-71

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 221.55  E-value: 1.28e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  71 PKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDM 150
Cdd:PRK14834  15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRDL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 151 PYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAM 230
Cdd:PRK14834  95 AELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDAETI 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240256454 231 EKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14834 175 SANLDT--ADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEY 233
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 70-291 1.05e-70

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 219.10  E-value: 1.05e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14832  18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLRRE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:PRK14832  98 LAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEQL 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14832 178 VEQHLYT--ADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSY 237
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 70-291 1.50e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 208.55  E-value: 1.50e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEK----RGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKY 145
Cdd:PRK14840  18 LPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLFNSQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 146 LASDMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDI 225
Cdd:PRK14840  98 LDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLANKKISSDDI 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256454 226 NEKAMEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14840 178 SEELISSYLDT--SGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTY 241
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
67-289 1.82e-65

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 205.38  E-value: 1.82e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  67 RNIMPK---HVAVILDGNRRWAEKRGLGTSEGHEAG---ARRLMENAKDcfaMGTNTISLFAFSTENWERPEDEVKCLMA 140
Cdd:PRK14839   3 SSLDRRsglHVAIIMDGNGRWATARGLPRLAGHRAGveaIRRVVEAAPD---LGIGTLTLYAFSSDNWRRPAAEVGGLMR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 141 LFEKYLASDMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANkvkdgli 220
Cdd:PRK14839  80 LLRAYLRNETERLARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAAKALG------- 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256454 221 qVEDINEKAMEKELltkCSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALT 289
Cdd:PRK14839 153 -PEGLSREAFSDLL---TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVA 217
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
70-291 4.53e-65

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 204.28  E-value: 4.53e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLKDE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEdINEKA 229
Cdd:PRK14833  84 RSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLLESPPSHIGELE-SLEEE 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14833 163 ISNCLDT--ADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDF 222
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 70-291 1.19e-63

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 200.60  E-value: 1.19e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGliQVEDINEKA 229
Cdd:PRK14841  83 MELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQG--KKIELTEET 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240256454 230 MEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14841 161 FRQYLYL--PDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESY 220
PRK14838 PRK14838
isoprenyl transferase;
62-291 4.39e-62

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 196.63  E-value: 4.39e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  62 KQKRGRNIMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMAL 141
Cdd:PRK14838   2 KEQIDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 142 FEKYLASDMpyLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQ 221
Cdd:PRK14838  82 LLDSIEEET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELN 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 222 VEDINEKAMEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14838 160 PEEITEESISEHLTT--NFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDY 227
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 67-291 9.13e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 193.46  E-value: 9.13e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  67 RNIMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYL 146
Cdd:PRK14829  11 KNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 147 ASDMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDIN 226
Cdd:PRK14829  91 HRRREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKISGDRVT 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240256454 227 EKAMEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14829 171 EKMISDHLYN--PDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEY 233
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
78-288 2.49e-59

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 189.42  E-value: 2.49e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  78 LDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASDMPYLRSDK 157
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 158 IKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKAMEKELltk 237
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHI--- 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 240256454 238 C-SEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEAL 288
Cdd:PRK10240 158 CmHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGAL 209
PRK14835 PRK14835
isoprenyl transferase;
64-291 1.11e-57

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 186.59  E-value: 1.11e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  64 KRGRniMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFE 143
Cdd:PRK14835  37 KHGK--LPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFE 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 144 K---YLASDmPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSL----ANKVK 216
Cdd:PRK14835 115 RearRMAVD-PRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLlleaAATGK 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240256454 217 DGLIQVEDINEKAMEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14835 194 SPEEVAAELTPEHISAHLYT--AGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDY 266
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 70-291 1.62e-57

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 185.19  E-value: 1.62e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGAR---RLMENAkdcFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYL 146
Cdd:PRK14842   8 IPAHIAVIMDGNGRWAESQGKKRSEGHREGANaidRLMDAS---LEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 147 ASDMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVED-I 225
Cdd:PRK14842  85 ETRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTLEKpL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256454 226 NEKAMEKELLTkcSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14842 165 KEKEFEKFLYT--SPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWY 228
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 71-291 5.45e-53

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 173.78  E-value: 5.45e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  71 PKHVAVILDGNRRWAEKRGLGT-SEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFE---KYL 146
Cdd:PRK14828  27 PGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIEdvvRQL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 147 ASDMPYlrsdkiKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDIN 226
Cdd:PRK14828 107 APDGRW------RVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKGTSIDELA 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256454 227 EK----AMEKELLTKCSefPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PRK14828 181 ESvtvdAISTHLYTGGQ--PDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDY 247
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 70-279 2.20e-52

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 173.60  E-value: 2.20e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  70 MPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYLASD 149
Cdd:PRK14827  67 LPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVRRR 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 150 MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKSLANKVKDGLIQVEDINEKA 229
Cdd:PRK14827 147 RDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLNPERITEST 226

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 240256454 230 MEKELltKCSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDF 279
Cdd:PRK14827 227 IARHL--QRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDY 274
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 67-284 1.06e-51

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 169.62  E-value: 1.06e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  67 RNIMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEKYL 146
Cdd:PRK14837   3 KNSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 147 ASDMPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYDILQACKslanKVKDGLIQVEDIN 226
Cdd:PRK14837  83 SSEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVK----KFLSSGLDLETLN 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 240256454 227 EKAMEKELltKCSEFPNPDLLIRTSGEQRISNFFLWQSAYTELYFPTVLWPDFGEAEY 284
Cdd:PRK14837 159 ENVFSKFL--DNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHY 214
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 65-291 2.07e-33

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 124.72  E-value: 2.07e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454  65 RGRnIMPKHVAVILDGNRRWAEKRGLGTSEGHEAGARRLMENAKDCFAMGTNTISLFAFSTENWERPEDEVKCLMALFEK 144
Cdd:PTZ00349  15 RDF-INIKHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLNLL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 145 YLASD---MPYLRSDKIKISVIGNRTKLPESLLGLIEEVEEATKSYEGKNLIIAIDYSGRYD------------------ 203
Cdd:PTZ00349  94 ILINEdffFKFIKDNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEmslckfnpnlyfdtyknl 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256454 204 -----ILQACKSLANKVKDGLIQVED----------------------------------INEKAME-----KELLTkcS 239
Cdd:PTZ00349 174 leekkILCGSNILTDPIKEGTFAIPDdedecdyldheleneridldlkfdgdcicgeksfLNEEQIEivnyhKKLLT--S 251

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 240256454 240 EFPNPDLLIRTSGEQRISNFFLWQ-SAYTELYFPTVLWPDFGEAEYLEALTWY 291
Cdd:PTZ00349 252 DLPPPNILIRTSGEKRLSDFMLYQiSEFTEIYFINEYWPIFNFLQFIYIILHY 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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