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Conserved domains on  [gi|18423105|ref|NP_568719|]
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Putative thiol-disulfide oxidoreductase DCC [Arabidopsis thaliana]

Protein Classification

thiol-disulfide oxidoreductase DCC family protein( domain architecture ID 10006848)

thiol-disulfide oxidoreductase DCC family protein is a DUF393 domain-containing protein, which may catalyze protein disulfide bond formation or reduction, and is a member of the DCC family of the thioredoxin superfamily; similar to Bacillus subtilis predicted thiol-disulfide oxidoreductase YuxK

Gene Ontology:  GO:0015035
PubMed:  15236740

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YuxK COG3011
Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];
68-188 2.46e-34

Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];


:

Pssm-ID: 442248  Cd Length: 133  Bit Score: 118.91  E-value: 2.46e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423105  68 PKPQNWKIKMLYDGDCPLCMREVNMLMERNeKHGTIKFVDISSNDYSPEDNqGLDYKTVMGQIHAIQSDGNVVKGVEAFR 147
Cdd:COG3011   2 PAPPPPKPIVLYDGVCPLCNREVRFLLRRD-RAGRFRFVPLQSEDGQLAAP-GLDPEDLLDSLHLIDEDGRVYTGSDAVL 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 18423105 148 RLYEEVGLGW--VYTITKFEPIGKLADVVYDVWAKYRLQVTGR 188
Cdd:COG3011  80 RILRALGGPWrlLAALLRLPGLRPLRDRLYRLVARNRYRLFGK 122
 
Name Accession Description Interval E-value
YuxK COG3011
Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];
68-188 2.46e-34

Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];


Pssm-ID: 442248  Cd Length: 133  Bit Score: 118.91  E-value: 2.46e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423105  68 PKPQNWKIKMLYDGDCPLCMREVNMLMERNeKHGTIKFVDISSNDYSPEDNqGLDYKTVMGQIHAIQSDGNVVKGVEAFR 147
Cdd:COG3011   2 PAPPPPKPIVLYDGVCPLCNREVRFLLRRD-RAGRFRFVPLQSEDGQLAAP-GLDPEDLLDSLHLIDEDGRVYTGSDAVL 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 18423105 148 RLYEEVGLGW--VYTITKFEPIGKLADVVYDVWAKYRLQVTGR 188
Cdd:COG3011  80 RILRALGGPWrlLAALLRLPGLRPLRDRLYRLVARNRYRLFGK 122
DCC1-like pfam04134
DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved ...
 78-188 3.75e-29

DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration. Uncharacterized proteins from bacteria are also included in this family.


Pssm-ID: 461189  Cd Length: 112  Bit Score: 105.08  E-value: 3.75e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423105    78 LYDGDCPLCMREVNMLMERNeKHGTIKFVDISSN-DYSPEDNQGLDYKTVMGQIHAiqSDGNVVKGVEAFRRLYEEVGL- 155
Cdd:pfam04134   2 FYDGVCPLCNREVRFLIRRD-RKGRIRFVDLQSApGFALLKEYGIDLEDADSRLHV--ERGRVYSGSDAFLAIWRALGGp 78

                          90       100       110
                  ....*....|....*....|....*....|....
gi 18423105   156 -GWVYTITKFEPIGKLADVVYDVWAKYRLQVTGR 188
Cdd:pfam04134  79 wRWLAALLRLPGLRPLRDRAYRLFARNRYRWFGK 112
 
Name Accession Description Interval E-value
YuxK COG3011
Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];
68-188 2.46e-34

Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];


Pssm-ID: 442248  Cd Length: 133  Bit Score: 118.91  E-value: 2.46e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423105  68 PKPQNWKIKMLYDGDCPLCMREVNMLMERNeKHGTIKFVDISSNDYSPEDNqGLDYKTVMGQIHAIQSDGNVVKGVEAFR 147
Cdd:COG3011   2 PAPPPPKPIVLYDGVCPLCNREVRFLLRRD-RAGRFRFVPLQSEDGQLAAP-GLDPEDLLDSLHLIDEDGRVYTGSDAVL 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 18423105 148 RLYEEVGLGW--VYTITKFEPIGKLADVVYDVWAKYRLQVTGR 188
Cdd:COG3011  80 RILRALGGPWrlLAALLRLPGLRPLRDRLYRLVARNRYRLFGK 122
DCC1-like pfam04134
DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved ...
 78-188 3.75e-29

DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration. Uncharacterized proteins from bacteria are also included in this family.


Pssm-ID: 461189  Cd Length: 112  Bit Score: 105.08  E-value: 3.75e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423105    78 LYDGDCPLCMREVNMLMERNeKHGTIKFVDISSN-DYSPEDNQGLDYKTVMGQIHAiqSDGNVVKGVEAFRRLYEEVGL- 155
Cdd:pfam04134   2 FYDGVCPLCNREVRFLIRRD-RKGRIRFVDLQSApGFALLKEYGIDLEDADSRLHV--ERGRVYSGSDAFLAIWRALGGp 78

                          90       100       110
                  ....*....|....*....|....*....|....
gi 18423105   156 -GWVYTITKFEPIGKLADVVYDVWAKYRLQVTGR 188
Cdd:pfam04134  79 wRWLAALLRLPGLRPLRDRAYRLFARNRYRWFGK 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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