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Conserved domains on  [gi|42568201|ref|NP_568573|]
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PROTEIN TARGETING TO STARCH (PTST) [Arabidopsis thaliana]

Protein Classification

glycogen-binding domain-containing protein( domain architecture ID 10120552)

glycogen-binding domain-containing protein similar to Saccharomyces cerevisiae cruciform DNA-recognizing protein 1 and signal transduction protein MDG1, which is involved in G-protein mediated signal transduction and in the regulation of polarized cell growth in pheromone-induced cells

Gene Ontology:  GO:0030246
SCOP:  4007532

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
E_set_AMPKbeta_like_N cd02859
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain ...
 192-272 2.25e-23

N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; E or "early" set domains are associated with the catalytic domain of AMP-activated protein kinase beta subunit glycogen binding domain at the N-terminal end. AMPK is a metabolic stress sensing protein that senses AMP/ATP and has recently been found to act as a glycogen sensor as well. The protein functions as an alpha-beta-gamma heterotrimer. This N-terminal domain is the glycogen binding domain of the beta subunit. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and isoamylase.


:

Pssm-ID: 199889 [Multi-domain]  Cd Length: 80  Bit Score: 90.74  E-value: 2.25e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568201 192 EVHVFWIGM-AESVQVMGSFDGWSQREDLSPEYSalfTKFSTTLFLRPGRYEMKFLVDGEWQISPEFPT-SGEGLMENNV 269
Cdd:cd02859   1 PVTFRWPGPgGKEVYVTGSFDNWQQPIPLEKSGD---GEFSATVELPPGRYEYKFIVDGEWVHDPDLPTvTDEFGNLNNV 77


                ...
gi 42568201 270 LVV 272
Cdd:cd02859  78 LEV 80
 
Name Accession Description Interval E-value
E_set_AMPKbeta_like_N cd02859
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain ...
 192-272 2.25e-23

N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; E or "early" set domains are associated with the catalytic domain of AMP-activated protein kinase beta subunit glycogen binding domain at the N-terminal end. AMPK is a metabolic stress sensing protein that senses AMP/ATP and has recently been found to act as a glycogen sensor as well. The protein functions as an alpha-beta-gamma heterotrimer. This N-terminal domain is the glycogen binding domain of the beta subunit. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and isoamylase.


Pssm-ID: 199889 [Multi-domain]  Cd Length: 80  Bit Score: 90.74  E-value: 2.25e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568201 192 EVHVFWIGM-AESVQVMGSFDGWSQREDLSPEYSalfTKFSTTLFLRPGRYEMKFLVDGEWQISPEFPT-SGEGLMENNV 269
Cdd:cd02859   1 PVTFRWPGPgGKEVYVTGSFDNWQQPIPLEKSGD---GEFSATVELPPGRYEYKFIVDGEWVHDPDLPTvTDEFGNLNNV 77


                ...
gi 42568201 270 LVV 272
Cdd:cd02859  78 LEV 80
AMPK1_CBM pfam16561
Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in ...
 197-272 6.59e-17

Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in close association with AMPKBI pfam04739. The surface of AMPK1_CBM reveals a carbohydrate-binding pocket.


Pssm-ID: 465176 [Multi-domain]  Cd Length: 85  Bit Score: 73.72  E-value: 6.59e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42568201   197 WIGMAESVQVMGSFDGWSQREDLSPEYSalftKFSTTLFLRPGRYEMKFLVDGEWQISPEFPTS--GEGLMeNNVLVV 272
Cdd:pfam16561   7 WRGGGKKVYVTGSFDNWKKKIPLQKSGG----DFTTILDLPPGTHQYKFIVDGEWRHDPDLPTAtdDMGNL-NNYIEV 79
 
Name Accession Description Interval E-value
E_set_AMPKbeta_like_N cd02859
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain ...
 192-272 2.25e-23

N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; E or "early" set domains are associated with the catalytic domain of AMP-activated protein kinase beta subunit glycogen binding domain at the N-terminal end. AMPK is a metabolic stress sensing protein that senses AMP/ATP and has recently been found to act as a glycogen sensor as well. The protein functions as an alpha-beta-gamma heterotrimer. This N-terminal domain is the glycogen binding domain of the beta subunit. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and isoamylase.


Pssm-ID: 199889 [Multi-domain]  Cd Length: 80  Bit Score: 90.74  E-value: 2.25e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568201 192 EVHVFWIGM-AESVQVMGSFDGWSQREDLSPEYSalfTKFSTTLFLRPGRYEMKFLVDGEWQISPEFPT-SGEGLMENNV 269
Cdd:cd02859   1 PVTFRWPGPgGKEVYVTGSFDNWQQPIPLEKSGD---GEFSATVELPPGRYEYKFIVDGEWVHDPDLPTvTDEFGNLNNV 77


                ...
gi 42568201 270 LVV 272
Cdd:cd02859  78 LEV 80
AMPK1_CBM pfam16561
Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in ...
 197-272 6.59e-17

Glycogen recognition site of AMP-activated protein kinase; AMPK1_CBM is a family found in close association with AMPKBI pfam04739. The surface of AMPK1_CBM reveals a carbohydrate-binding pocket.


Pssm-ID: 465176 [Multi-domain]  Cd Length: 85  Bit Score: 73.72  E-value: 6.59e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42568201   197 WIGMAESVQVMGSFDGWSQREDLSPEYSalftKFSTTLFLRPGRYEMKFLVDGEWQISPEFPTS--GEGLMeNNVLVV 272
Cdd:pfam16561   7 WRGGGKKVYVTGSFDNWKKKIPLQKSGG----DFTTILDLPPGTHQYKFIVDGEWRHDPDLPTAtdDMGNL-NNYIEV 79
E_set_Isoamylase_like_N cd07184
N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also ...
 201-272 7.49e-05

N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins; E or "early" set domains are associated with the catalytic domain of isoamylase-like proteins at the N-terminal end. Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. Isoamylase contains a bound calcium ion, but this is not in the same position as the conserved calcium ion that has been reported in other alpha-amylase family enzymes. The N-terminal domain of isoamylase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and the beta subunit of AMP-activated protein kinase.


Pssm-ID: 199892 [Multi-domain]  Cd Length: 86  Bit Score: 40.69  E-value: 7.49e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568201 201 AESVQVMGSFDGWSQRED---LSPEYSalftkFSTTLFLRPG-RYEMKFLVDGE-----WQiSPEFPTSGEGlMENNVLV 271
Cdd:cd07184  13 ADSVSLVGDFNDWDPQATpmkKLKNGT-----FSATLDLPAGrEYQFRYLIDGErwvndPE-ADAYAPNGFG-EENSVVS 85


                .
gi 42568201 272 V 272
Cdd:cd07184  86 V 86
E_set cd02688
Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the ...
 201-255 1.06e-04

Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; The E or "early" set domains of sugar utilizing enzymes are associated with different types of catalytic domains at either the N-terminal or C-terminal end. These domains may be related to the immunoglobulin and/or fibronectin type III superfamilies. Members of this family include alpha amylase, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase. A subset of these members were recently identified as members of the CBM48 (Carbohydrate Binding Module 48) family. Members of the CBM48 family include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, isoamylase, and the beta subunit of AMP-activated protein kinase.


Pssm-ID: 199878 [Multi-domain]  Cd Length: 82  Bit Score: 39.83  E-value: 1.06e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 42568201 201 AESVQVMGSFDGWSQREDLsPEYSALFTKFSTTLFLRPGRYEMKFLVDGEWQISP 255
Cdd:cd02688  11 AKSVYLIGSFNGWWQAQAL-PMTKNGGGVWSATIPLPLGTYEYKYVIDGGKNVLP 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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