NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|18418258|ref|NP_567930|]
View 

costars family protein [Arabidopsis thaliana]

Protein Classification

costars family protein( domain architecture ID 10631454)

costars family protein similar to Dictyostelium discoideum protein costars that modulates actin dynamics and cell motility

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Costars pfam14705
Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating ...
 2-78 3.48e-36

Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility. It has a winged helix-like fold consisting of three alpha-helices and four antiparallel beta strands. Unlike typical winged helix proteins it does not bind to DNA, but contains a hydrophobic groove which may be responsible for interaction with other proteins.


:

Pssm-ID: 464274 [Multi-domain]  Cd Length: 76  Bit Score: 117.21  E-value: 3.48e-36
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18418258    2 NVDEEIQKLEEEIHRLGSRQTDGSYKVTFGVLFndDRCANIFEALVGTLRAAKKRKIVAFEGELLLQGVHDKVEITL 78
Cdd:pfam14705  1 HVDREILELCEIIKRLGTKDADGKIVVTFGVLF--ERYANISEKLVGTLLRARKHGLVDFEGEMLLQGRDDDVDITL 75
 
Name Accession Description Interval E-value
Costars pfam14705
Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating ...
 2-78 3.48e-36

Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility. It has a winged helix-like fold consisting of three alpha-helices and four antiparallel beta strands. Unlike typical winged helix proteins it does not bind to DNA, but contains a hydrophobic groove which may be responsible for interaction with other proteins.


Pssm-ID: 464274 [Multi-domain]  Cd Length: 76  Bit Score: 117.21  E-value: 3.48e-36
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18418258    2 NVDEEIQKLEEEIHRLGSRQTDGSYKVTFGVLFndDRCANIFEALVGTLRAAKKRKIVAFEGELLLQGVHDKVEITL 78
Cdd:pfam14705  1 HVDREILELCEIIKRLGTKDADGKIVVTFGVLF--ERYANISEKLVGTLLRARKHGLVDFEGEMLLQGRDDDVDITL 75
 
Name Accession Description Interval E-value
Costars pfam14705
Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating ...
 2-78 3.48e-36

Costars; This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility. It has a winged helix-like fold consisting of three alpha-helices and four antiparallel beta strands. Unlike typical winged helix proteins it does not bind to DNA, but contains a hydrophobic groove which may be responsible for interaction with other proteins.


Pssm-ID: 464274 [Multi-domain]  Cd Length: 76  Bit Score: 117.21  E-value: 3.48e-36
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18418258    2 NVDEEIQKLEEEIHRLGSRQTDGSYKVTFGVLFndDRCANIFEALVGTLRAAKKRKIVAFEGELLLQGVHDKVEITL 78
Cdd:pfam14705  1 HVDREILELCEIIKRLGTKDADGKIVVTFGVLF--ERYANISEKLVGTLLRARKHGLVDFEGEMLLQGRDDDVDITL 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH