F-box and associated interaction domains-containing protein [Arabidopsis thaliana]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | |||||
| F_box_assoc_1 super family | cl44343 | F-box protein interaction domain; This model describes a large family of plant domains, with ... |
101-337 | 2.60e-24 | |||||
F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain. The actual alignment was detected with superfamily member TIGR01640: Pssm-ID: 273726 [Multi-domain] Cd Length: 230 Bit Score: 100.13 E-value: 2.60e-24
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| F-box_SF super family | cl45894 | F-box domain superfamily; This short domain is commonly found at the N-terminus of various ... |
16-49 | 3.28e-08 | |||||
F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures. The actual alignment was detected with superfamily member cd22157: Pssm-ID: 459239 Cd Length: 39 Bit Score: 49.00 E-value: 3.28e-08
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| Name | Accession | Description | Interval | E-value | |||||
| F_box_assoc_1 | TIGR01640 | F-box protein interaction domain; This model describes a large family of plant domains, with ... |
101-337 | 2.60e-24 | |||||
F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain. Pssm-ID: 273726 [Multi-domain] Cd Length: 230 Bit Score: 100.13 E-value: 2.60e-24
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| F-box_AtFBW1-like | cd22157 | F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ... |
16-49 | 3.28e-08 | |||||
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438928 Cd Length: 39 Bit Score: 49.00 E-value: 3.28e-08
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| FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
16-53 | 9.84e-07 | |||||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 45.12 E-value: 9.84e-07
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| F-box | pfam00646 | F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ... |
16-49 | 6.71e-05 | |||||
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 425796 Cd Length: 43 Bit Score: 39.83 E-value: 6.71e-05
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| Name | Accession | Description | Interval | E-value | |||||
| F_box_assoc_1 | TIGR01640 | F-box protein interaction domain; This model describes a large family of plant domains, with ... |
101-337 | 2.60e-24 | |||||
F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain. Pssm-ID: 273726 [Multi-domain] Cd Length: 230 Bit Score: 100.13 E-value: 2.60e-24
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| F-box_AtFBW1-like | cd22157 | F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) ... |
16-49 | 3.28e-08 | |||||
F-box domain found in Arabidopsis thaliana F-box/WD-40 repeat-containing protein 1 (AtFBW1) and similar proteins; AtFBW1, also called WD-40-associated F-box protein 1, is an F-box protein that contains four WD-40 repeats, which are separated from each other by a spacer region. Like other F-box proteins, AtFBW1 may be a component of SCF (Skp1 Cdc53 F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. This subfamily also contains many F-box only proteins that do not have any WD repeat. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438928 Cd Length: 39 Bit Score: 49.00 E-value: 3.28e-08
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| FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
16-53 | 9.84e-07 | |||||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 45.12 E-value: 9.84e-07
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| F-box | pfam00646 | F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ... |
16-49 | 6.71e-05 | |||||
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 425796 Cd Length: 43 Bit Score: 39.83 E-value: 6.71e-05
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| F-box_AtAFR-like | cd22152 | F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and ... |
16-46 | 2.45e-03 | |||||
F-box domain found in Arabidopsis thaliana protein ATTENUATED FAR-RED RESPONSE (AtAFR) and similar proteins; AtAFR, also called SKP1-interacting partner 29 (AtSKIP29), or F-box protein AFR, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It is part of the phyA-mediated signaling transduction pathway leading to the regulation of gene expression and hypocotyl elongation in response to red and far-red light exposure. This subfamily also includes many other Arabidopsis thaliana SKP1-interacting partner proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438923 Cd Length: 45 Bit Score: 35.62 E-value: 2.45e-03
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