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Conserved domains on  [gi|18405657|ref|NP_566833|]
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nodulin MtN21 /EamA-like transporter family protein [Arabidopsis thaliana]

Protein Classification

DMT family transporter( domain architecture ID 706274)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others; similar to Arabidopsis thaliana protein WALLS ARE THIN 1 (WAT1) and WAT1-related proteins

Gene Ontology:  GO:0016020|GO:0022857
PubMed:  11432728
TCDB:  2.A.7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00411 super family cl28283
nodulin MtN21 family protein; Provisional
 2-269 2.74e-126

nodulin MtN21 family protein; Provisional


The actual alignment was detected with superfamily member PLN00411:

Pssm-ID: 177805 [Multi-domain]  Cd Length: 358  Bit Score: 363.12  E-value: 2.74e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657    2 STYLITGFIGIEYSNPTLASAISNINPAITFILAIIFRMEKASFKEKSSVAKMVGTIVSLVGALVVVLYHGPRVFTPSSP 81
Cdd:PLN00411  89 SMYVITGYIGIEYSNPTLASAISNITPALTFILAIIFRMEKVSFKERSSVAKVMGTILSLIGALVVIFYHGPRVFVASSP 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657   82 PFPQLRQLLLPLSSSNSDWIIGGCLLAIKDTLVPVAFILQAHIMKLYPAPFTVSFFYFLIASILTSLIGIVAEKNNPSIW 161
Cdd:PLN00411 169 PYLNFRQLSPPLSSSNSDWLIGGALLTIQGIFVSVSFILQAHIMSEYPAAFTVSFLYTVCVSIVTSMIGLVVEKNNPSVW 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657  162 IIHFDITLVCIVVGGIFNPGYYAIHLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVMW 241
Cdd:PLN00411 249 IIHFDITLITIVTMAIITSVYYVIHSWTVRHKGPLYLAIFKPLSILIAVVMGAIFLNDSLYLGCLIGGILITLGFYAVMW 328

                        250       260       270
                 ....*....|....*....|....*....|
gi 18405657  242 GKAKEGKTQFLSLS--EETPLLDENIDDRI 269
Cdd:PLN00411 329 GKANEEKDQLLSFSgkEKTPLLLNGKNDQI 358
 
Name Accession Description Interval E-value
PLN00411 PLN00411
nodulin MtN21 family protein; Provisional
 2-269 2.74e-126

nodulin MtN21 family protein; Provisional


Pssm-ID: 177805 [Multi-domain]  Cd Length: 358  Bit Score: 363.12  E-value: 2.74e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657    2 STYLITGFIGIEYSNPTLASAISNINPAITFILAIIFRMEKASFKEKSSVAKMVGTIVSLVGALVVVLYHGPRVFTPSSP 81
Cdd:PLN00411  89 SMYVITGYIGIEYSNPTLASAISNITPALTFILAIIFRMEKVSFKERSSVAKVMGTILSLIGALVVIFYHGPRVFVASSP 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657   82 PFPQLRQLLLPLSSSNSDWIIGGCLLAIKDTLVPVAFILQAHIMKLYPAPFTVSFFYFLIASILTSLIGIVAEKNNPSIW 161
Cdd:PLN00411 169 PYLNFRQLSPPLSSSNSDWLIGGALLTIQGIFVSVSFILQAHIMSEYPAAFTVSFLYTVCVSIVTSMIGLVVEKNNPSVW 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657  162 IIHFDITLVCIVVGGIFNPGYYAIHLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVMW 241
Cdd:PLN00411 249 IIHFDITLITIVTMAIITSVYYVIHSWTVRHKGPLYLAIFKPLSILIAVVMGAIFLNDSLYLGCLIGGILITLGFYAVMW 328

                        250       260       270
                 ....*....|....*....|....*....|
gi 18405657  242 GKAKEGKTQFLSLS--EETPLLDENIDDRI 269
Cdd:PLN00411 329 GKANEEKDQLLSFSgkEKTPLLLNGKNDQI 358
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 1-245 4.46e-12

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 64.86  E-value: 4.46e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657   1 MSTYLITGFIGIEYSNPTLASAISNINPAITFILAIIFrmekasFKEKSSVAKMVGTIVSLVGALVVVlyhGPRVFTPSS 80
Cdd:COG0697  76 LALAFLLFFLALQYTPAALAALLLALAPLFVALLAALL------LGERLSRRRWLGLLLGFAGVLLIV---GPGGGGGGG 146

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657  81 PPFPQLrqlllplsssnsdWIIGGCLLAikdtlvPVAFILQAHIMKLYPaPFTVSFFYFLIASILTSLIGIVAEKNNPSI 160
Cdd:COG0697 147 SLLGDL-------------LALLAALSW------ALYTVLTRRLSRRLD-PLTLTFWQMLVGALLLLPLALLTGLPLPLS 206

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657 161 WIIHFDITLVCIVVGGIfnpGYYAIhLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVM 240
Cdd:COG0697 207 AAAWLALLYLGLFGTAL---AYLLW-FRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282


                ....*
gi 18405657 241 WGKAK 245
Cdd:COG0697 283 LRERR 287
 
Name Accession Description Interval E-value
PLN00411 PLN00411
nodulin MtN21 family protein; Provisional
 2-269 2.74e-126

nodulin MtN21 family protein; Provisional


Pssm-ID: 177805 [Multi-domain]  Cd Length: 358  Bit Score: 363.12  E-value: 2.74e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657    2 STYLITGFIGIEYSNPTLASAISNINPAITFILAIIFRMEKASFKEKSSVAKMVGTIVSLVGALVVVLYHGPRVFTPSSP 81
Cdd:PLN00411  89 SMYVITGYIGIEYSNPTLASAISNITPALTFILAIIFRMEKVSFKERSSVAKVMGTILSLIGALVVIFYHGPRVFVASSP 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657   82 PFPQLRQLLLPLSSSNSDWIIGGCLLAIKDTLVPVAFILQAHIMKLYPAPFTVSFFYFLIASILTSLIGIVAEKNNPSIW 161
Cdd:PLN00411 169 PYLNFRQLSPPLSSSNSDWLIGGALLTIQGIFVSVSFILQAHIMSEYPAAFTVSFLYTVCVSIVTSMIGLVVEKNNPSVW 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657  162 IIHFDITLVCIVVGGIFNPGYYAIHLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVMW 241
Cdd:PLN00411 249 IIHFDITLITIVTMAIITSVYYVIHSWTVRHKGPLYLAIFKPLSILIAVVMGAIFLNDSLYLGCLIGGILITLGFYAVMW 328

                        250       260       270
                 ....*....|....*....|....*....|
gi 18405657  242 GKAKEGKTQFLSLS--EETPLLDENIDDRI 269
Cdd:PLN00411 329 GKANEEKDQLLSFSgkEKTPLLLNGKNDQI 358
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 1-245 4.46e-12

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 64.86  E-value: 4.46e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657   1 MSTYLITGFIGIEYSNPTLASAISNINPAITFILAIIFrmekasFKEKSSVAKMVGTIVSLVGALVVVlyhGPRVFTPSS 80
Cdd:COG0697  76 LALAFLLFFLALQYTPAALAALLLALAPLFVALLAALL------LGERLSRRRWLGLLLGFAGVLLIV---GPGGGGGGG 146

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657  81 PPFPQLrqlllplsssnsdWIIGGCLLAikdtlvPVAFILQAHIMKLYPaPFTVSFFYFLIASILTSLIGIVAEKNNPSI 160
Cdd:COG0697 147 SLLGDL-------------LALLAALSW------ALYTVLTRRLSRRLD-PLTLTFWQMLVGALLLLPLALLTGLPLPLS 206

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405657 161 WIIHFDITLVCIVVGGIfnpGYYAIhLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVM 240
Cdd:COG0697 207 AAAWLALLYLGLFGTAL---AYLLW-FRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAA 282


                ....*
gi 18405657 241 WGKAK 245
Cdd:COG0697 283 LRERR 287
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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