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Conserved domains on  [gi|18405582|ref|NP_566828|]
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beta-galactosidase [Arabidopsis thaliana]

Protein Classification

mitochondrial porin family protein( domain architecture ID 1295)

mitochondrial porin family protein is found in the outer membrane of mitochondria and is a pore-forming protein that allows ions and small molecules to pass through the membrane

Gene Ontology:  GO:0015288
PubMed:  11450972

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Porin3 super family cl03224
Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin ...
183-361 7.31e-04

Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane, a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.


The actual alignment was detected with superfamily member cd07303:

Pssm-ID: 470762 [Multi-domain]  Cd Length: 274  Bit Score: 41.11  E-value: 7.31e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 183 PKHAWLVSKMGSLTVGVQYEPLHGSK-DLAKYTDPR----NWSCAAGYgvgSQSPLTPSFNIGIELARSSQFIASFYQHV 257
Cdd:cd07303  67 FTEKWNTDNTLGLEITVEDQLSRGLKsTFDSSFSPNtgkkNAKIKTGY---KRINLGCDVDFDIAGPLIRGALVLGYEGW 143
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 258 V-----VQRRVQNPFEENQVVGI-TNYIDF----------GF----------ELQSRVDDSKTPPNApDSLLQVAASWQA 311
Cdd:cd07303 144 LagyqmVFETVSRVTQSNFAVGYkTDYNEFqahtnvndgtEFggsiyhkvndKLEVGVNLAATAGNS-NTRFGIAAKYQV 222
                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 18405582 312 NKNFLLKGKVGAhSSTLSLAFKSWWKPSFAFNISATTNHRTGNVQCGFGL 361
Cdd:cd07303 223 DPDACFSASVNN-SSLVGLGYTQTLKPGIKLTLSALLDHKAGGHKLGLGL 271
 
Name Accession Description Interval E-value
Porin3 cd07303
Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin ...
183-361 7.31e-04

Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane, a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.


Pssm-ID: 132765 [Multi-domain]  Cd Length: 274  Bit Score: 41.11  E-value: 7.31e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 183 PKHAWLVSKMGSLTVGVQYEPLHGSK-DLAKYTDPR----NWSCAAGYgvgSQSPLTPSFNIGIELARSSQFIASFYQHV 257
Cdd:cd07303  67 FTEKWNTDNTLGLEITVEDQLSRGLKsTFDSSFSPNtgkkNAKIKTGY---KRINLGCDVDFDIAGPLIRGALVLGYEGW 143
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 258 V-----VQRRVQNPFEENQVVGI-TNYIDF----------GF----------ELQSRVDDSKTPPNApDSLLQVAASWQA 311
Cdd:cd07303 144 LagyqmVFETVSRVTQSNFAVGYkTDYNEFqahtnvndgtEFggsiyhkvndKLEVGVNLAATAGNS-NTRFGIAAKYQV 222
                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 18405582 312 NKNFLLKGKVGAhSSTLSLAFKSWWKPSFAFNISATTNHRTGNVQCGFGL 361
Cdd:cd07303 223 DPDACFSASVNN-SSLVGLGYTQTLKPGIKLTLSALLDHKAGGHKLGLGL 271
 
Name Accession Description Interval E-value
Porin3 cd07303
Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin ...
183-361 7.31e-04

Eukaryotic porin family that forms channels in the mitochondrial outer membrane; The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane, a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.


Pssm-ID: 132765 [Multi-domain]  Cd Length: 274  Bit Score: 41.11  E-value: 7.31e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 183 PKHAWLVSKMGSLTVGVQYEPLHGSK-DLAKYTDPR----NWSCAAGYgvgSQSPLTPSFNIGIELARSSQFIASFYQHV 257
Cdd:cd07303  67 FTEKWNTDNTLGLEITVEDQLSRGLKsTFDSSFSPNtgkkNAKIKTGY---KRINLGCDVDFDIAGPLIRGALVLGYEGW 143
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18405582 258 V-----VQRRVQNPFEENQVVGI-TNYIDF----------GF----------ELQSRVDDSKTPPNApDSLLQVAASWQA 311
Cdd:cd07303 144 LagyqmVFETVSRVTQSNFAVGYkTDYNEFqahtnvndgtEFggsiyhkvndKLEVGVNLAATAGNS-NTRFGIAAKYQV 222
                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|
gi 18405582 312 NKNFLLKGKVGAhSSTLSLAFKSWWKPSFAFNISATTNHRTGNVQCGFGL 361
Cdd:cd07303 223 DPDACFSASVNN-SSLVGLGYTQTLKPGIKLTLSALLDHKAGGHKLGLGL 271
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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