NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|79416719|ref|NP_566757|]
View 

receptor like protein 40 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 144-843 2.58e-60

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 222.42  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  144 SSISSKFGMLNNLEvlslSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFAR-NLRKLRVLDVSYNHFSGILnPNSS 222
Cdd:PLN00113  39 SSINDPLKYLSNWN----SSADVCLWQGITCNNSSRVVSIDLSGKNISGKISSAIfRLPYIQTINLSNNQLSGPI-PDDI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  223 LFELHHIIYLNLRYNNFTSsslPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLPL-VQNLTKL 301
Cdd:PLN00113 114 FTTSSSLRYLNLSNNNFTG---SIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  302 SILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGsiEVPNSssssrleslhlgenhfegkilepISKLINLKELDLSF 381
Cdd:PLN00113 191 EFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG--EIPYE-----------------------IGGLTSLNHLDLVY 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  382 LNTSYPIdlslfsslkslllldlsgdwiskasltldsyipstlevlrlehcdisdfPNVFKTLHNLEYIALSNNRISGKF 461
Cdd:PLN00113 246 NNLTGPI-------------------------------------------------PSSLGNLKNLQYLFLYQNKLSGPI 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  462 PEWLWSLPRLSSVFITDNLLTGfEGSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAI---DNRFGGDIPLSICNR 538
Cdd:PLN00113 277 PPSIFSLQKLISLDLSDNSLSG-EIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLqlwSNKFSGEIPKNLGKH 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  539 SSLDVLDLSYNNFTGPIPPCL---SNLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSV 615
Cdd:PLN00113 356 NNLTVLDLSTNNLTGEIPEGLcssGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDI 435

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  616 DHNGIKDTFPFSLKALPKLQVLLLSSNKFYGPLspPNEgpLGFPELRILEIAGNKLTGSFLSSdffvnwkasshtmnedl 695
Cdd:PLN00113 436 SNNNLQGRINSRKWDMPSLQMLSLARNKFFGGL--PDS--FGSKRLENLDLSRNQFSGAVPRK----------------- 494

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  696 glymvygkviFGNYHltyyETIDLrykglsmeqrnvltssatiDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPL 775
Cdd:PLN00113 495 ----------LGSLS----ELMQL-------------------KLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPA 541

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79416719  776 SFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQGTQITGQPKSSFEGNAGLCG 843
Cdd:PLN00113 542 SFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 144-843 2.58e-60

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 222.42  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  144 SSISSKFGMLNNLEvlslSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFAR-NLRKLRVLDVSYNHFSGILnPNSS 222
Cdd:PLN00113  39 SSINDPLKYLSNWN----SSADVCLWQGITCNNSSRVVSIDLSGKNISGKISSAIfRLPYIQTINLSNNQLSGPI-PDDI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  223 LFELHHIIYLNLRYNNFTSsslPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLPL-VQNLTKL 301
Cdd:PLN00113 114 FTTSSSLRYLNLSNNNFTG---SIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  302 SILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGsiEVPNSssssrleslhlgenhfegkilepISKLINLKELDLSF 381
Cdd:PLN00113 191 EFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG--EIPYE-----------------------IGGLTSLNHLDLVY 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  382 LNTSYPIdlslfsslkslllldlsgdwiskasltldsyipstlevlrlehcdisdfPNVFKTLHNLEYIALSNNRISGKF 461
Cdd:PLN00113 246 NNLTGPI-------------------------------------------------PSSLGNLKNLQYLFLYQNKLSGPI 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  462 PEWLWSLPRLSSVFITDNLLTGfEGSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAI---DNRFGGDIPLSICNR 538
Cdd:PLN00113 277 PPSIFSLQKLISLDLSDNSLSG-EIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLqlwSNKFSGEIPKNLGKH 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  539 SSLDVLDLSYNNFTGPIPPCL---SNLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSV 615
Cdd:PLN00113 356 NNLTVLDLSTNNLTGEIPEGLcssGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDI 435

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  616 DHNGIKDTFPFSLKALPKLQVLLLSSNKFYGPLspPNEgpLGFPELRILEIAGNKLTGSFLSSdffvnwkasshtmnedl 695
Cdd:PLN00113 436 SNNNLQGRINSRKWDMPSLQMLSLARNKFFGGL--PDS--FGSKRLENLDLSRNQFSGAVPRK----------------- 494

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  696 glymvygkviFGNYHltyyETIDLrykglsmeqrnvltssatiDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPL 775
Cdd:PLN00113 495 ----------LGSLS----ELMQL-------------------KLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPA 541

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79416719  776 SFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQGTQITGQPKSSFEGNAGLCG 843
Cdd:PLN00113 542 SFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-439 3.79e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.09  E-value: 3.79e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 110 QLRACLSGTLKPNSSLFQFHHLRSLLLPHNNFTSssISSKFGMLNNLEVLSLSSSGfLAQVPFSFSNLSMLSALVLSNND 189
Cdd:COG4886  94 DLTNLTELDLSGNEELSNLTNLESLDLSGNQLTD--LPEELANLTNLKELDLSNNQ-LTDLPEPLGNLTNLKSLDLSNNQ 170

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 190 LTGSLSFARNLRKLRVLDVSYNHFSGIlnpNSSLFELHHIIYLNLRYNNFTSssLPYEFGNLNKLEVLDVSSNSFfgQVP 269
Cdd:COG4886 171 LTDLPEELGNLTNLKELDLSNNQITDL---PEPLGNLTNLEELDLSGNQLTD--LPEPLANLTNLETLDLSNNQL--TDL 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 270 PTISNLTQLTELYLPLNHFTgSLPLVQNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEVPNSSSSSR 349
Cdd:COG4886 244 PELGNLTNLEELDLSNNQLT-DLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 350 LESLHLGENHFEGKILEPISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKASLTLDSYIPSTLEVLRL 429
Cdd:COG4886 323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLL 402

                       330
                ....*....|
gi 79416719 430 EHCDISDFPN 439
Cdd:COG4886 403 LTLALLDAVN 412
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 174-289 1.58e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 47.09  E-value: 1.58e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 174 FSNLSMLSALVLSNNDLTgSLSFARNLRKLRVLDVSYNHFSGI--LNPNSSLFELH------------------------ 227
Cdd:cd21340  42 LEFLTNLTHLYLQNNQIE-KIENLENLVNLKKLYLGGNRISVVegLENLTNLEELHienqrlppgekltfdprslaalsn 120

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79416719 228 HIIYLNLRYNNFTSSSlpyEFGNLNKLEVLDVSSNSF--FGQVPPTISNLTQLTELYLPLNHFT 289
Cdd:cd21340 121 SLRVLNISGNNIDSLE---PLAPLRNLEQLDASNNQIsdLEELLDLLSSWPSLRELDLTGNPVC 181
LRR_8 pfam13855
Leucine rich repeat;
422-481 3.19e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 3.19e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79416719   422 STLEVLRLEHCDISDF-PNVFKTLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLL 481
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 144-843 2.58e-60

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 222.42  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  144 SSISSKFGMLNNLEvlslSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFAR-NLRKLRVLDVSYNHFSGILnPNSS 222
Cdd:PLN00113  39 SSINDPLKYLSNWN----SSADVCLWQGITCNNSSRVVSIDLSGKNISGKISSAIfRLPYIQTINLSNNQLSGPI-PDDI 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  223 LFELHHIIYLNLRYNNFTSsslPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLPL-VQNLTKL 301
Cdd:PLN00113 114 FTTSSSLRYLNLSNNNFTG---SIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSL 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  302 SILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGsiEVPNSssssrleslhlgenhfegkilepISKLINLKELDLSF 381
Cdd:PLN00113 191 EFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG--EIPYE-----------------------IGGLTSLNHLDLVY 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  382 LNTSYPIdlslfsslkslllldlsgdwiskasltldsyipstlevlrlehcdisdfPNVFKTLHNLEYIALSNNRISGKF 461
Cdd:PLN00113 246 NNLTGPI-------------------------------------------------PSSLGNLKNLQYLFLYQNKLSGPI 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  462 PEWLWSLPRLSSVFITDNLLTGfEGSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAI---DNRFGGDIPLSICNR 538
Cdd:PLN00113 277 PPSIFSLQKLISLDLSDNSLSG-EIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLqlwSNKFSGEIPKNLGKH 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  539 SSLDVLDLSYNNFTGPIPPCL---SNLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSV 615
Cdd:PLN00113 356 NNLTVLDLSTNNLTGEIPEGLcssGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDI 435

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  616 DHNGIKDTFPFSLKALPKLQVLLLSSNKFYGPLspPNEgpLGFPELRILEIAGNKLTGSFLSSdffvnwkasshtmnedl 695
Cdd:PLN00113 436 SNNNLQGRINSRKWDMPSLQMLSLARNKFFGGL--PDS--FGSKRLENLDLSRNQFSGAVPRK----------------- 494

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  696 glymvygkviFGNYHltyyETIDLrykglsmeqrnvltssatiDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPL 775
Cdd:PLN00113 495 ----------LGSLS----ELMQL-------------------KLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPA 541

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79416719  776 SFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQGTQITGQPKSSFEGNAGLCG 843
Cdd:PLN00113 542 SFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 139-627 2.49e-50

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 192.37  E-value: 2.49e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  139 NNFTSSSISSKFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSL-SFARNLRKLRVLDVSYNHFSG-I 216
Cdd:PLN00113 149 NNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIpRELGQMKSLKWIYLGYNNLSGeI 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  217 LNPNSSLFELHHiiyLNLRYNNFTsSSLPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLP-LV 295
Cdd:PLN00113 229 PYEIGGLTSLNH---LDLVYNNLT-GPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPeLV 304

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  296 QNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEvPNSSSSSRLESLHLGENHFEGKILEPISKLINLK 375
Cdd:PLN00113 305 IQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIP-KNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLF 383

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  376 ELDLsFLNtsypidlslfsslkslllldlsgdwiskaslTLDSYIPSTLEVLRlehcdisdfpnvfktlhNLEYIALSNN 455
Cdd:PLN00113 384 KLIL-FSN-------------------------------SLEGEIPKSLGACR-----------------SLRRVRLQDN 414

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  456 RISGKFPEWLWSLPRLSSVFITDNLLTGfEGSSEVLVNSSVQILSLDTNSLEGALPHLPLS--INYFSAIDNRFGGDIPL 533
Cdd:PLN00113 415 SFSGELPSEFTKLPLVYFLDISNNNLQG-RINSRKWDMPSLQMLSLARNKFFGGLPDSFGSkrLENLDLSRNQFSGAVPR 493

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  534 SICNRSSLDVLDLSYNNFTGPIPPCLS---NLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSAL 610
Cdd:PLN00113 494 KLGSLSELMQLKLSENKLSGEIPDELSsckKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESL 573

                        490
                 ....*....|....*..
gi 79416719  611 QFLSVDHNGIKDTFPFS 627
Cdd:PLN00113 574 VQVNISHNHLHGSLPST 590
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-439 3.79e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.09  E-value: 3.79e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 110 QLRACLSGTLKPNSSLFQFHHLRSLLLPHNNFTSssISSKFGMLNNLEVLSLSSSGfLAQVPFSFSNLSMLSALVLSNND 189
Cdd:COG4886  94 DLTNLTELDLSGNEELSNLTNLESLDLSGNQLTD--LPEELANLTNLKELDLSNNQ-LTDLPEPLGNLTNLKSLDLSNNQ 170

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 190 LTGSLSFARNLRKLRVLDVSYNHFSGIlnpNSSLFELHHIIYLNLRYNNFTSssLPYEFGNLNKLEVLDVSSNSFfgQVP 269
Cdd:COG4886 171 LTDLPEELGNLTNLKELDLSNNQITDL---PEPLGNLTNLEELDLSGNQLTD--LPEPLANLTNLETLDLSNNQL--TDL 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 270 PTISNLTQLTELYLPLNHFTgSLPLVQNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEVPNSSSSSR 349
Cdd:COG4886 244 PELGNLTNLEELDLSNNQLT-DLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 350 LESLHLGENHFEGKILEPISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKASLTLDSYIPSTLEVLRL 429
Cdd:COG4886 323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLL 402

                       330
                ....*....|
gi 79416719 430 EHCDISDFPN 439
Cdd:COG4886 403 LTLALLDAVN 412
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 130-364 6.72e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 89.14  E-value: 6.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  130 HLRSLLLPHNNFtSSSISSKFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFAR-NLRKLRVLDV 208
Cdd:PLN00113 381 NLFKLILFSNSL-EGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKwDMPSLQMLSL 459

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  209 SYNHFSGilnpnsslfelhhiiylnlrynnftssSLPYEFGNlNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHF 288
Cdd:PLN00113 460 ARNKFFG---------------------------GLPDSFGS-KRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKL 511

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 79416719  289 TGSLP-LVQNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEvPNSSSSSRLESLHLGENHFEGKI 364
Cdd:PLN00113 512 SGEIPdELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIP-KNLGNVESLVQVNISHNHLHGSL 587
PLN03150 PLN03150
hypothetical protein; Provisional
 745-850 1.02e-16

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 84.87  E-value: 1.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  745 LEGEIPESIGLLKALIALNLSNNAFTGHIPLSFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQ- 823
Cdd:PLN03150 430 LRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAa 509

                         90       100
                 ....*....|....*....|....*...
gi 79416719  824 -GTQITGQPKSSFEGNAGLCGFPLQESC 850
Cdd:PLN03150 510 lGGRLLHRASFNFTDNAGLCGIPGLRAC 537
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
134-565 6.38e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 81.13  E-value: 6.38e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 134 LLLPHNNFTSSSISSKFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFARNLRKLRVLDVSYNHF 213
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 214 SGILNPNSSLFELHHIIYLNLRYNNftssslpyEFGNLNKLEVLDVSSNSfFGQVPPTISNLTQLTELYLPLNHFTGSLP 293
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSGNE--------ELSNLTNLESLDLSGNQ-LTDLPEELANLTNLKELDLSNNQLTDLPE 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 294 LVQNLTKLSILHLFGNHFSgTIPSSLFTMPFLSYLSLKGNNLNgsiEVPNS-SSSSRLESLHLGENHFEgKILEPISKLI 372
Cdd:COG4886 154 PLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT---DLPEPlGNLTNLEELDLSGNQLT-DLPEPLANLT 228

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 373 NLKELDLSFLNTSypidlslfsslkslllldlsgDWISKASLTldsyipsTLEVLRLEHCDISDFPNVFKtLHNLEYIAL 452
Cdd:COG4886 229 NLETLDLSNNQLT---------------------DLPELGNLT-------NLEELDLSNNQLTDLPPLAN-LTNLKTLDL 279

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 453 SNNRISGKFPEWLWSLPRLSSVFITDNLLTGFEGSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAIDNRFGGDIP 532
Cdd:COG4886 280 SNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLL 359

                       410       420       430
                ....*....|....*....|....*....|...
gi 79416719 533 LSICNRSSLDVLDLSYNNFTGPIPPCLSNLLYL 565
Cdd:COG4886 360 SLLLTLLLTLGLLGLLEATLLTLALLLLTLLLL 392
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
158-686 7.05e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 7.05e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 158 VLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFARNLRKLRVLDVSYNHFSGILNPNSSLFELHHIIYLNLRYN 237
Cdd:COG4886   2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 238 NFTSSSLPYEFGNLNKLEVLDVSSNsffgqvpPTISNLTQLTELYLPLNHFTGSLPLVQNLTKLSILHLFGNHFSgTIPS 317
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DLPE 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 318 SLFTMPFLSYLSLKGNNLNGsievpnsssssrleslhlgenhfegkILEPISKLINLKELDLSflntsypidlslfsslk 397
Cdd:COG4886 154 PLGNLTNLKSLDLSNNQLTD--------------------------LPEELGNLTNLKELDLS----------------- 190

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 398 slllldlsgdwiskasltldsyipstlevlrleHCDISDFPNVFKTLHNLEYIALSNNRISgKFPEWLWSLPRLSSVFIT 477
Cdd:COG4886 191 ---------------------------------NNQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLS 236

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 478 DNLLTgfegssevlvnssvqilsldtnslegalphlplsinyfsaidnrfggDIPlSICNRSSLDVLDLSYNNFTGpIPP 557
Cdd:COG4886 237 NNQLT-----------------------------------------------DLP-ELGNLTNLEELDLSNNQLTD-LPP 267

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 558 C--LSNLLYLKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLP-RSLINCSALQFLSVDHNGIKDTFPFSLKALPKL 634
Cdd:COG4886 268 LanLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELlILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLL 347

                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|..
gi 79416719 635 QVLLLSSNKFYGPLSPPNEGPLGFPELRILEIAGNKLTGSFLSSDFFVNWKA 686
Cdd:COG4886 348 ALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
333-678 1.40e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 67.65  E-value: 1.40e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 333 NNLNGSIEVPNSSSSSRLESLHLGENHFEGKILEPISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKA 412
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 413 SLTLDSYIPSTLEVL-RLEHCDISDFPNVFKtLHNLEYIALSNNRISgKFPEWLWSLPRLSSVFITDNLLTGFegSSEVL 491
Cdd:COG4886  81 LLSLLLLGLTDLGDLtNLTELDLSGNEELSN-LTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTDL--PEPLG 156

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 492 VNSSVQILSLDTNSLEgalphlplsinyfsaidnrfggDIPLSICNRSSLDVLDLSYNNFTgPIPPCLSNLlylklrknn 571
Cdd:COG4886 157 NLTNLKSLDLSNNQLT----------------------DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNL--------- 204

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 572 legsipdkyyedTPLRSLDVGYNRLTgKLPRSLINCSALQFLSVDHNGIKDtFPfSLKALPKLQVLLLSSNKFYgplSPP 651
Cdd:COG4886 205 ------------TNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLTD-LP-ELGNLTNLEELDLSNNQLT---DLP 266

                       330       340
                ....*....|....*....|....*..
gi 79416719 652 NEGPLgfPELRILEIAGNKLTGSFLSS 678
Cdd:COG4886 267 PLANL--TNLKTLDLSNNQLTDLKLKE 291
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
443-875 1.37e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.57  E-value: 1.37e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 443 TLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLLTGFEgSSEVLVNSSVQILSLDTNSLEGALPHLPLSINYFSA 522
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLL-SLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 523 IDNRFGGDIPLSICNRSSLDVLDLSYNNFTGPippcLSNLLYLKLRKNNLEgSIPDKYYEDTPLRSLDVGYNRLTgKLPR 602
Cdd:COG4886  80 LLLSLLLLGLTDLGDLTNLTELDLSGNEELSN----LTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT-DLPE 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 603 SLINCSALQFLSVDHNGIKDtFPFSLKALPKLQVLLLSSNKFY---GPLSppnegplGFPELRILEIAGNKLTgsflssd 679
Cdd:COG4886 154 PLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITdlpEPLG-------NLTNLEELDLSGNQLT------- 218

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 680 ffvnwkasshTMNEDLGLymvygkvifgnyhltyyetidlrykglsmeqrnvLTSSATIDFSGNRLEgEIPEsIGLLKAL 759
Cdd:COG4886 219 ----------DLPEPLAN----------------------------------LTNLETLDLSNNQLT-DLPE-LGNLTNL 252

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 760 IALNLSNNAFTgHIPLSfANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQLIGEIPQGTQITGQPKSSFEGNA 839
Cdd:COG4886 253 EELDLSNNQLT-DLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330

                       410       420       430
                ....*....|....*....|....*....|....*.
gi 79416719 840 GLCGFPLQESCFGTNTPPAQHPKEQEEEEEDEQVLN 875
Cdd:COG4886 331 KGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLL 366
PLN03150 PLN03150
hypothetical protein; Provisional
 244-319 3.89e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 60.21  E-value: 3.89e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 79416719  244 LPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLP-LVQNLTKLSILHLFGNHFSGTIPSSL 319
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPeSLGQLTSLRILNLNGNSLSGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
 499-604 7.03e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 59.44  E-value: 7.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  499 LSLDTNSLEGALPHLPLSINYFSAI---DNRFGGDIPLSICNRSSLDVLDLSYNNFTGPIPPCLSNLlylklrknnlegs 575
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSInlsGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQL------------- 489

                         90       100
                 ....*....|....*....|....*....
gi 79416719  576 ipdkyyedTPLRSLDVGYNRLTGKLPRSL 604
Cdd:PLN03150 490 --------TSLRILNLNGNSLSGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
 226-293 1.30e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.59  E-value: 1.30e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79416719  226 LHHIIYLNLRyNNFTSSSLPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLP 293
Cdd:PLN03150 441 LRHLQSINLS-GNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
PLN03150 PLN03150
hypothetical protein; Provisional
 93-204 1.06e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.51  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719   93 PWNGVWC--DDSTGA--VTMLQL-RACLSGTLkPNSsLFQFHHLRSLLLPhNNFTSSSISSKFGMLNNLEVLSLSSSGFL 167
Cdd:PLN03150 403 PWSGADCqfDSTKGKwfIDGLGLdNQGLRGFI-PND-ISKLRHLQSINLS-GNSIRGNIPPSLGSITSLEVLDLSYNSFN 479

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 79416719  168 AQVPFSFSNLSMLSALVLSNNDLTGSLSFARNLRKLR 204
Cdd:PLN03150 480 GSIPESLGQLTSLRILNLNGNSLSGRVPAALGGRLLH 516
PLN03150 PLN03150
hypothetical protein; Provisional
 257-342 1.11e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.51  E-value: 1.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  257 LDVSSNSFFGQVPPTISNLTQLTELYLPLNHFTGSLPL-VQNLTKLSILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNL 335
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPsLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                 ....*..
gi 79416719  336 NGsiEVP 342
Cdd:PLN03150 503 SG--RVP 507
PLN03150 PLN03150
hypothetical protein; Provisional
 541-632 1.21e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.13  E-value: 1.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  541 LDVLDLSYNNFTGPIPPCLSNLLYLK---LRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSVDH 617
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPNDISKLRHLQsinLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNG 499

                         90
                 ....*....|....*
gi 79416719  618 NGIKDTFPFSLKALP 632
Cdd:PLN03150 500 NSLSGRVPAALGGRL 514
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 174-289 1.58e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 47.09  E-value: 1.58e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 174 FSNLSMLSALVLSNNDLTgSLSFARNLRKLRVLDVSYNHFSGI--LNPNSSLFELH------------------------ 227
Cdd:cd21340  42 LEFLTNLTHLYLQNNQIE-KIENLENLVNLKKLYLGGNRISVVegLENLTNLEELHienqrlppgekltfdprslaalsn 120

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79416719 228 HIIYLNLRYNNFTSSSlpyEFGNLNKLEVLDVSSNSF--FGQVPPTISNLTQLTELYLPLNHFT 289
Cdd:cd21340 121 SLRVLNISGNNIDSLE---PLAPLRNLEQLDASNNQIsdLEELLDLLSSWPSLRELDLTGNPVC 181
PLN03150 PLN03150
hypothetical protein; Provisional
 159-269 2.60e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.89  E-value: 2.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  159 LSLSSSGFLAQVPFSFSNLSMLSALVLSNNDLTGSLSFA-RNLRKLRVLDVSYNHFSGilnpnsslfelhhiiylnlryn 237
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSlGSITSLEVLDLSYNSFNG---------------------- 480

                         90       100       110
                 ....*....|....*....|....*....|..
gi 79416719  238 nftssSLPYEFGNLNKLEVLDVSSNSFFGQVP 269
Cdd:PLN03150 481 -----SIPESLGQLTSLRILNLNGNSLSGRVP 507
LRR_8 pfam13855
Leucine rich repeat;
422-481 3.19e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 3.19e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79416719   422 STLEVLRLEHCDISDF-PNVFKTLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLL 481
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 565-646 4.46e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.12  E-value: 4.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  565 LKLRKNNLEGSIPDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSVDHNGIKDTFPFSLKALPKLQVLLLSSNKF 644
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                 ..
gi 79416719  645 YG 646
Cdd:PLN03150 503 SG 504
LRR_8 pfam13855
Leucine rich repeat;
201-264 1.10e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 1.10e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 79416719   201 RKLRVLDVSYNHFSGIlnPNSSLFELHHIIYLNLRYNNFTSSSlPYEFGNLNKLEVLDVSSNSF 264
Cdd:pfam13855   1 PNLRSLDLSNNRLTSL--DDGAFKGLSNLKVLDLSNNLLTTLS-PGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 437-525 1.21e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 45.96  E-value: 1.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  437 FPNVFKTLHNLEYIALSNNRISGKFPEWLWSLPRLSSVFITDNLLTGFEGSSEVLVnSSVQILSLDTNSLEGALPH---- 512
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQL-TSLRILNLNGNSLSGRVPAalgg 512

                         90
                 ....*....|...
gi 79416719  513 LPLSINYFSAIDN 525
Cdd:PLN03150 513 RLLHRASFNFTDN 525
PLN03150 PLN03150
hypothetical protein; Provisional
 732-803 3.56e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.42  E-value: 3.56e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 79416719  732 LTSSATIDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSF-ANLKKMESLDLSSNQLSGTIPnGLRT 803
Cdd:PLN03150 465 ITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALgGRLLHRASFNFTDNAGLCGIP-GLRA 536
LRR_8 pfam13855
Leucine rich repeat;
762-817 5.63e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 5.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 79416719   762 LNLSNNAFTGHIPLSFANLKKMESLDLSSNQLSGTIPNGLRTLSFLAYVNVSHNQL 817
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 596-673 6.88e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 6.88e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 79416719  596 LTGKLPRSLINCSALQFLSVDHNGIKDTFPFSLKALPKLQVLLLSSNKFYGPLsPPNEGPLGfpELRILEIAGNKLTG 673
Cdd:PLN03150 430 LRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSI-PESLGQLT--SLRILNLNGNSLSG 504
LRR_8 pfam13855
Leucine rich repeat;
737-793 1.01e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 1.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 79416719   737 TIDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSFANLKKMESLDLSSNQL 793
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 97-263 2.46e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 2.46e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719  97 VWCDDSTGAVTmLQLRACLSGtLKPNSSLFQFHHLRSLLLPHNNFTSSSISSKFgmlnNLEVLSLSSSG-------FLAQ 169
Cdd:cd00116  57 CLSLNETGRIP-RGLQSLLQG-LTKGCGLQELDLSDNALGPDGCGVLESLLRSS----SLQELKLNNNGlgdrglrLLAK 130

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 170 VPFSfsNLSMLSALVLSNNDLTGSLSFA-----RNLRKLRVLDVSYNHF--SGILNPNSSLFELHHIIYLNLRYNNFTS- 241
Cdd:cd00116 131 GLKD--LPPALEKLVLGRNRLEGASCEAlakalRANRDLKELNLANNGIgdAGIRALAEGLKANCNLEVLDLNNNGLTDe 208

                       170       180
                ....*....|....*....|....
gi 79416719 242 --SSLPYEFGNLNKLEVLDVSSNS 263
Cdd:cd00116 209 gaSALAETLASLKSLEVLNLGDNN 232
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 275-460 3.25e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.15  E-value: 3.25e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 275 LTQLTELYLPLNHFTgSLPLVQNLTKLSILHLFGNHFSgTIPSsLFTMPFLSYLSLKGNNLNgSIEvpNSSSSSRLESLH 354
Cdd:cd21340   1 LKRITHLYLNDKNIT-KIDNLSLCKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIE-KIE--NLENLVNLKKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79416719 355 LGENHFEgkILEPISKLINLKELDLS----FLNTSYPIDLSLFsslkslllldlsgDWISKaSLT--------LDSYIP- 421
Cdd:cd21340  75 LGGNRIS--VVEGLENLTNLEELHIEnqrlPPGEKLTFDPRSL-------------AALSN-SLRvlnisgnnIDSLEPl 138

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 79416719 422 ---STLEVLRLEHCDISDFP---NVFKTLHNLEYIALSNNRISGK 460
Cdd:cd21340 139 aplRNLEQLDASNNQISDLEellDLLSSWPSLRELDLTGNPVCKK 183
PLN03150 PLN03150
hypothetical protein; Provisional
 496-563 3.29e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.34  E-value: 3.29e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79416719  496 VQILSLDTNSLEGALPHLPLSINYFSAID---NRFGGDIPLSICNRSSLDVLDLSYNNFTGPIPPCLSNLL 563
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDlsyNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALGGRL 514
LRR_8 pfam13855
Leucine rich repeat;
560-620 4.63e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 4.63e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 79416719   560 SNLLYLKLRKNNLEgSIPDKYYEDTP-LRSLDVGYNRLTGKLPRSLINCSALQFLSVDHNGI 620
Cdd:pfam13855   1 PNLRSLDLSNNRLT-SLDDGAFKGLSnLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
130-190 7.01e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 7.01e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 79416719   130 HLRSLLLPHNNFTSSSISSkFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDL 190
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGA-FKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH