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Conserved domains on  [gi|42564151|ref|NP_566484|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase; tannase/feruloyl esterase family alpha/beta hydrolase( domain architecture ID 10791498)

uncharacterized alpha/beta hydrolase; may catalyze the cleavage and formation of ester bonds| tannase/feruloyl esterase family alpha/beta hydrolase similar to Aspergillus oryzae tannase and Aspergillus niger feruloyl esterase B

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02934 PLN02934
triacylglycerol lipase
 8-518 0e+00

triacylglycerol lipase


:

Pssm-ID: 215504  Cd Length: 515  Bit Score: 936.51  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151    8 GSGSNPGQVSNYLIVRPHRGGYIDLFRYGVRDDQTSKAKFLEMPDNRewstiTIDEEAEDHRWVIVVSILVRKIIRLLRT 87
Cdd:PLN02934   1 MDDASPTTGTNYLIVRPDKGGFLDLFRYLVRGDQGSGAKFLESSDER-----VPGEEAVDHRWVILVSIIIRKIIALFGT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   88 PMEFTGFVVDFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLYKEWNFVEHLEGIDSVDSGRVKI 167
Cdd:PLN02934  76 PMEYTGFVVDFFLNLFSQNGGFLGLLLNLLQGKVVIPQRGSETFISTIGHLDGRIDLYKTPNLVEQLDDSVSNHNSKIKG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  168 ELGSRGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDA 247
Cdd:PLN02934 156 ELGNRALMDLCIMASKLAYENAKVVENVVDHHWKMHFVAFYNCWNDFQKQMSTQVFIFCDKPKDANLIVISFRGTEPFDA 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  248 DDWGTDFDYSWYEVPNVGKLHMGFLEAMGLGNRDDTTTFHYNLFEQTSS--EEENSKKNLLDMVERSAYYAVRVILKRLL 325
Cdd:PLN02934 236 DDWGTDFDYSWYEIPKVGKVHMGFLEAMGLGNRDDTTTFQTSLQTKATSelKEEESKKNLLEMVERSAYYAVRSKLKSLL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  326 SEHENARFVVTGHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIV 405
Cdd:PLN02934 316 KEHKNAKFVVTGHSLGGALAILFPTVLVLQEETEVMKRLLGVYTFGQPRIGNRQLGKFMEAQLNYPVPRYFRVVYCNDLV 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  406 PRLPYDDKTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRL 485
Cdd:PLN02934 396 PRLPYDDKTFLYKHFGVCLYYDSRYFGQKMDEEPDRNPFGLRNAISAHLNAVWELWRSFIMGYTHGPEYKEGWFSIFFRI 475

                        490       500       510
                 ....*....|....*....|....*....|...
gi 42564151  486 MGLVIPGLSDHCMTDYVNSVRLGPDNELQMSSL 518
Cdd:PLN02934 476 MGLVLPGVAAHSPTDYVNSVRLGRERVVPMSSL 508
 
Name Accession Description Interval E-value
PLN02934 PLN02934
triacylglycerol lipase
 8-518 0e+00

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 936.51  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151    8 GSGSNPGQVSNYLIVRPHRGGYIDLFRYGVRDDQTSKAKFLEMPDNRewstiTIDEEAEDHRWVIVVSILVRKIIRLLRT 87
Cdd:PLN02934   1 MDDASPTTGTNYLIVRPDKGGFLDLFRYLVRGDQGSGAKFLESSDER-----VPGEEAVDHRWVILVSIIIRKIIALFGT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   88 PMEFTGFVVDFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLYKEWNFVEHLEGIDSVDSGRVKI 167
Cdd:PLN02934  76 PMEYTGFVVDFFLNLFSQNGGFLGLLLNLLQGKVVIPQRGSETFISTIGHLDGRIDLYKTPNLVEQLDDSVSNHNSKIKG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  168 ELGSRGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDA 247
Cdd:PLN02934 156 ELGNRALMDLCIMASKLAYENAKVVENVVDHHWKMHFVAFYNCWNDFQKQMSTQVFIFCDKPKDANLIVISFRGTEPFDA 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  248 DDWGTDFDYSWYEVPNVGKLHMGFLEAMGLGNRDDTTTFHYNLFEQTSS--EEENSKKNLLDMVERSAYYAVRVILKRLL 325
Cdd:PLN02934 236 DDWGTDFDYSWYEIPKVGKVHMGFLEAMGLGNRDDTTTFQTSLQTKATSelKEEESKKNLLEMVERSAYYAVRSKLKSLL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  326 SEHENARFVVTGHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIV 405
Cdd:PLN02934 316 KEHKNAKFVVTGHSLGGALAILFPTVLVLQEETEVMKRLLGVYTFGQPRIGNRQLGKFMEAQLNYPVPRYFRVVYCNDLV 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  406 PRLPYDDKTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRL 485
Cdd:PLN02934 396 PRLPYDDKTFLYKHFGVCLYYDSRYFGQKMDEEPDRNPFGLRNAISAHLNAVWELWRSFIMGYTHGPEYKEGWFSIFFRI 475

                        490       500       510
                 ....*....|....*....|....*....|...
gi 42564151  486 MGLVIPGLSDHCMTDYVNSVRLGPDNELQMSSL 518
Cdd:PLN02934 476 MGLVLPGVAAHSPTDYVNSVRLGRERVVPMSSL 508
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 172-427 1.65e-49

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 169.96  E-value: 1.65e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 172 RGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFL--DCWNDYQKQMSTQVFVFTDKqkDANLIVISFRGTEPFDadD 249
Cdd:cd00519   2 YEKLKYYAKLAAAAYCVDANILAKAVVFADIALLNVFspDKLLKTDKQYDTQGYVAVDH--DRKTIVIAFRGTVSLA--D 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 250 WGTDFDYSW----YEVPNVGKLHMGFLEAMglgnrddtttfhynlfeqtsseeenskknlldmveRSAYYAVRVILKRLL 325
Cdd:cd00519  78 WLTDLDFSPvpldPPLCSGGKVHSGFYSAY-----------------------------------KSLYNQVLPELKSAL 122

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 326 SEHENARFVVTGHSLGGALAILFPTLLVLNEeteiMKRLLGVYTFGQPRIGNREvglfMKAQLNQPVDRYFRVVYCNDIV 405
Cdd:cd00519 123 KQYPDYKIIVTGHSLGGALASLLALDLRLRG----PGSDVTVYTFGQPRVGNAA----FAEYLESTKGRVYRVVHGNDIV 194

                       250       260
                ....*....|....*....|....
gi 42564151 406 PRLPYDDK--TFLYKHFGLCLFYD 427
Cdd:cd00519 195 PRLPPGSLtpPEGYTHVGTEVWID 218
Lipase_3 pfam01764
Lipase (class 3);
236-412 7.45e-39

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 138.16  E-value: 7.45e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   236 VISFRGTEpfDADDWGTDFDYSWYE----VPNVGKLHMGFLEAMglgnrddtttfhynlfeqtsseeenskknlldmveR 311
Cdd:pfam01764   1 VVAFRGTN--SILDWLTDFDFSLTPfkdfFLGGGKVHSGFLSAY-----------------------------------T 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   312 SAYYAVRVILKRLLSEHENARFVVTGHSLGGALAILFPTLLVLNEETEimKRLLGVYTFGQPRIGNREVGLFMKAQLNqp 391
Cdd:pfam01764  44 SVREQVLAELKRLLEKYPDYSIVVTGHSLGGALASLAALDLVENGLRL--SSRVTVVTFGQPRVGNLEFAKLHDSQGP-- 119

                         170       180
                  ....*....|....*....|.
gi 42564151   392 vDRYFRVVYCNDIVPRLPYDD 412
Cdd:pfam01764 120 -KFSYRVVHQRDIVPRLPPIV 139
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
216-429 8.86e-26

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 106.38  E-value: 8.86e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 216 KQMSTQVFVFTDKQKDAnlIVISFRGTEPFDadDWGTDFDY---SWYEVPNVGKLHMGFLEAmglgnrddtttfhynlfe 292
Cdd:COG3675  12 TQGDPEVFGFILRSDDE--VIVAFRGTESLT--DWLTNLNAaqvPYPFAKTGGKVHRGFYRA------------------ 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 293 qtsseeenskknlldmversaYYAVRVILKRLLSE-HENARFVVTGHSLGGALAILFPTLLVLNEeteiMKRLLGVYTFG 371
Cdd:COG3675  70 ---------------------LQSLRELLEDALRPlSPGKRLYVTGHSLGGALATLAAADLERNY----IFPVRGLYTFG 124

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 42564151 372 QPRIGNREvglFMKaQLNQPVDRYFRVVYCNDIVPRLPYDDktFLYKHFGLCLFYDSF 429
Cdd:COG3675 125 QPRVGDRS---FAK-YYNLHVPNSYRIVNNNDIVPLLPPVW--MGYDHVGKLLWLDSL 176
 
Name Accession Description Interval E-value
PLN02934 PLN02934
triacylglycerol lipase
 8-518 0e+00

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 936.51  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151    8 GSGSNPGQVSNYLIVRPHRGGYIDLFRYGVRDDQTSKAKFLEMPDNRewstiTIDEEAEDHRWVIVVSILVRKIIRLLRT 87
Cdd:PLN02934   1 MDDASPTTGTNYLIVRPDKGGFLDLFRYLVRGDQGSGAKFLESSDER-----VPGEEAVDHRWVILVSIIIRKIIALFGT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   88 PMEFTGFVVDFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLYKEWNFVEHLEGIDSVDSGRVKI 167
Cdd:PLN02934  76 PMEYTGFVVDFFLNLFSQNGGFLGLLLNLLQGKVVIPQRGSETFISTIGHLDGRIDLYKTPNLVEQLDDSVSNHNSKIKG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  168 ELGSRGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDA 247
Cdd:PLN02934 156 ELGNRALMDLCIMASKLAYENAKVVENVVDHHWKMHFVAFYNCWNDFQKQMSTQVFIFCDKPKDANLIVISFRGTEPFDA 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  248 DDWGTDFDYSWYEVPNVGKLHMGFLEAMGLGNRDDTTTFHYNLFEQTSS--EEENSKKNLLDMVERSAYYAVRVILKRLL 325
Cdd:PLN02934 236 DDWGTDFDYSWYEIPKVGKVHMGFLEAMGLGNRDDTTTFQTSLQTKATSelKEEESKKNLLEMVERSAYYAVRSKLKSLL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  326 SEHENARFVVTGHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIV 405
Cdd:PLN02934 316 KEHKNAKFVVTGHSLGGALAILFPTVLVLQEETEVMKRLLGVYTFGQPRIGNRQLGKFMEAQLNYPVPRYFRVVYCNDLV 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  406 PRLPYDDKTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRL 485
Cdd:PLN02934 396 PRLPYDDKTFLYKHFGVCLYYDSRYFGQKMDEEPDRNPFGLRNAISAHLNAVWELWRSFIMGYTHGPEYKEGWFSIFFRI 475

                        490       500       510
                 ....*....|....*....|....*....|...
gi 42564151  486 MGLVIPGLSDHCMTDYVNSVRLGPDNELQMSSL 518
Cdd:PLN02934 476 MGLVLPGVAAHSPTDYVNSVRLGRERVVPMSSL 508
PLN00413 PLN00413
triacylglycerol lipase
 15-508 9.20e-160

triacylglycerol lipase


Pssm-ID: 165792  Cd Length: 479  Bit Score: 462.95  E-value: 9.20e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   15 QVSNYLIVRPHRGGYIDLFRYGVRDDQTSKaKFLEmpdnrewstiTIDEEAEDH------RWVIVVSILVRKIIRLLRTP 88
Cdd:PLN00413   3 QPKNYFVLDPREATVSDLIHLLFSSDLEDR-KFID----------SSEENIEDDlcefrgRWIIFVSIVIQKLIIIFKKP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   89 MEFTGFVVDFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLykewnfvehlegidsvDSGRvKIE 168
Cdd:PLN00413  72 LSFLGFALACWLNLLSSNGGFFKIFLNLFKGNFIWPEKASATFASINGNLDQKVEL----------------GLGP-KIE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  169 LGS-RGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDA 247
Cdd:PLN00413 135 IGDeRYKALLSIMASKLAYENEHFIRSVLHDHWKMDLLGFYSCPNDFDKQRSTEVIVIKDTKDDPNLIIVSFRGTDPFDA 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  248 DDWGTDFDYSWYEVPNVGKLHMGFLEAMGLGNRddtttfhyNLFEQTSSEEENSKKNLLdmversAYYAVRVILKRLLSE 327
Cdd:PLN00413 215 DDWCTDLDLSWHEVKNVGKIHGGFMKALGLPKE--------GWPEEINLDETQNATSLL------AYYTILRHLKEIFDQ 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  328 HENARFVVTGHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIVPR 407
Cdd:PLN00413 281 NPTSKFILSGHSLGGALAILFTAVLIMHDEEEMLERLEGVYTFGQPRVGDEDFGIFMKDKLKEFDVKYERYVYCNDMVPR 360

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  408 LPYDDKTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRLMG 487
Cdd:PLN00413 361 LPFDDKTLMFKHFGACLYCDSFYKGKVEEEEPNKNYFNIFWVIPKIINALWELIRSFIIPCWKGGEFREGWFLRCFRLVA 440

                        490       500
                 ....*....|....*....|.
gi 42564151  488 LVIPGLSDHCMTDYVNSVRLG 508
Cdd:PLN00413 441 LLIPGLPAHFPNEYINVALLG 461
PLN02162 PLN02162
triacylglycerol lipase
 17-508 1.14e-114

triacylglycerol lipase


Pssm-ID: 177821  Cd Length: 475  Bit Score: 347.42  E-value: 1.14e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   17 SNYLIVRPHRGGYIDLFRYGVRDDQTSkAKFLEMPDNrewsTITIDEEAEDHRWVIVVSILVRKIIRLLRTPMEFTGFVV 96
Cdd:PLN02162   5 NSYFLVDPTKASFLDLLLLLFSFNLTS-ARFIDSPPD----TLKGFRRSFASRWILALAIFLQKVLMLLSKPFAFIGQKL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   97 DFFLNLFSANGGFFGLLLRLIQAKVVIPERGSVTFVSTIGQLDGRISLYKEwnfvehlegidsVDSGrvKIELGSRglmd 176
Cdd:PLN02162  80 TYWLNLLTANGGFFNLILNLLSGKLVKPDKSSATYTSFIGCSDRRIELDEK------------IDVG--SIEYKSM---- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  177 LCVMASKLAYENAKVVENVVDLHWKMNLVEFLDCWNDYQKQMSTQVFVFTDKQKDANLIVISFRGTEPFDADDWGTDFDY 256
Cdd:PLN02162 142 LSIMASKISYESKPFINSVVKNTWKMDLVGNYDFYNAFQESKLTQAFVFKTSSTNPDLIVVSFRGTEPFEAADWCTDLDL 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  257 SWYEVPNVGKLHMGFLEAMGLgnrddtttfhynlfeqtsSEEENSKKNLLDMVERSAYYAVRVILKRLLSEHENARFVVT 336
Cdd:PLN02162 222 SWYELKNVGKVHAGFSRALGL------------------QKDGGWPKENISLLHQYAYYTIRQMLRDKLARNKNLKYILT 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  337 GHSLGGALAILFPTLLVLNEETEIMKRLLGVYTFGQPRIGNREVGLFMKAQLNQPVDRYFRVVYCNDIVPRLPYDDK-TF 415
Cdd:PLN02162 284 GHSLGGALAALFPAILAIHGEDELLDKLEGIYTFGQPRVGDEDFGEFMKGVVKKHGIEYERFVYNNDVVPRVPFDDKlLF 363

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  416 LYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKILGHVIAVWELVRGLTMGYTHGPDYKEGWFRILFRLMGLVIPGLSD 495
Cdd:PLN02162 364 SYKHYGPCNSFNSLYKGKVREDAPNANYFNLLWLIPQLLTGLWEFIRSFILQFWKGDEYKENWLMRFVRVVGIVFPGGSN 443

                        490
                 ....*....|...
gi 42564151  496 HCMTDYVNSVRLG 508
Cdd:PLN02162 444 HFPFDYVNSTRLG 456
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 172-427 1.65e-49

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 169.96  E-value: 1.65e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 172 RGLMDLCVMASKLAYENAKVVENVVDLHWKMNLVEFL--DCWNDYQKQMSTQVFVFTDKqkDANLIVISFRGTEPFDadD 249
Cdd:cd00519   2 YEKLKYYAKLAAAAYCVDANILAKAVVFADIALLNVFspDKLLKTDKQYDTQGYVAVDH--DRKTIVIAFRGTVSLA--D 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 250 WGTDFDYSW----YEVPNVGKLHMGFLEAMglgnrddtttfhynlfeqtsseeenskknlldmveRSAYYAVRVILKRLL 325
Cdd:cd00519  78 WLTDLDFSPvpldPPLCSGGKVHSGFYSAY-----------------------------------KSLYNQVLPELKSAL 122

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 326 SEHENARFVVTGHSLGGALAILFPTLLVLNEeteiMKRLLGVYTFGQPRIGNREvglfMKAQLNQPVDRYFRVVYCNDIV 405
Cdd:cd00519 123 KQYPDYKIIVTGHSLGGALASLLALDLRLRG----PGSDVTVYTFGQPRVGNAA----FAEYLESTKGRVYRVVHGNDIV 194

                       250       260
                ....*....|....*....|....
gi 42564151 406 PRLPYDDK--TFLYKHFGLCLFYD 427
Cdd:cd00519 195 PRLPPGSLtpPEGYTHVGTEVWID 218
Lipase_3 pfam01764
Lipase (class 3);
236-412 7.45e-39

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 138.16  E-value: 7.45e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   236 VISFRGTEpfDADDWGTDFDYSWYE----VPNVGKLHMGFLEAMglgnrddtttfhynlfeqtsseeenskknlldmveR 311
Cdd:pfam01764   1 VVAFRGTN--SILDWLTDFDFSLTPfkdfFLGGGKVHSGFLSAY-----------------------------------T 43

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151   312 SAYYAVRVILKRLLSEHENARFVVTGHSLGGALAILFPTLLVLNEETEimKRLLGVYTFGQPRIGNREVGLFMKAQLNqp 391
Cdd:pfam01764  44 SVREQVLAELKRLLEKYPDYSIVVTGHSLGGALASLAALDLVENGLRL--SSRVTVVTFGQPRVGNLEFAKLHDSQGP-- 119

                         170       180
                  ....*....|....*....|.
gi 42564151   392 vDRYFRVVYCNDIVPRLPYDD 412
Cdd:pfam01764 120 -KFSYRVVHQRDIVPRLPPIV 139
Lipase cd00741
Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and ...
 311-451 1.42e-28

Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238382 [Multi-domain]  Cd Length: 153  Bit Score: 110.67  E-value: 1.42e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 311 RSAYYAVRVILKRLLSEHENARFVVTGHSLGGALAILFPTLLVLNEEteimKRLLGVYTFGQPRIGNREvgLFMKAQLNQ 390
Cdd:cd00741   8 RSLANLVLPLLKSALAQYPDYKIHVTGHSLGGALAGLAGLDLRGRGL----GRLVRVYTFGPPRVGNAA--FAEDRLDPS 81

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42564151 391 PVDRYFRVVYCNDIVPRLPYDdkTFLYKHFGLCLFYDSFYNETKAEDEPDPNPYGLRYKIL 451
Cdd:cd00741  82 DALFVDRIVNDNDIVPRLPPG--GEGYPHGGAEFYINGGKSQPGCCKNVLEAVDIDFGNIG 140
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
216-429 8.86e-26

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 106.38  E-value: 8.86e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 216 KQMSTQVFVFTDKQKDAnlIVISFRGTEPFDadDWGTDFDY---SWYEVPNVGKLHMGFLEAmglgnrddtttfhynlfe 292
Cdd:COG3675  12 TQGDPEVFGFILRSDDE--VIVAFRGTESLT--DWLTNLNAaqvPYPFAKTGGKVHRGFYRA------------------ 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151 293 qtsseeenskknlldmversaYYAVRVILKRLLSE-HENARFVVTGHSLGGALAILFPTLLVLNEeteiMKRLLGVYTFG 371
Cdd:COG3675  70 ---------------------LQSLRELLEDALRPlSPGKRLYVTGHSLGGALATLAAADLERNY----IFPVRGLYTFG 124

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 42564151 372 QPRIGNREvglFMKaQLNQPVDRYFRVVYCNDIVPRLPYDDktFLYKHFGLCLFYDSF 429
Cdd:COG3675 125 QPRVGDRS---FAK-YYNLHVPNSYRIVNNNDIVPLLPPVW--MGYDHVGKLLWLDSL 176
PLN02310 PLN02310
triacylglycerol lipase
 235-422 1.58e-10

triacylglycerol lipase


Pssm-ID: 215176  Cd Length: 405  Bit Score: 63.08  E-value: 1.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  235 IVISFRGTepFDADDWGTDFDYSwyevpnvgklhmgfLEAMGLGNrddtTTFHYNLFEQTSSEEENSKKNLLDMVERSAY 314
Cdd:PLN02310 134 IMVAWRGT--VAPSEWFLDLETK--------------LEHIDNTN----VKVQEGFLKIYKSKDESTRYNKLSASEQVMQ 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  315 YAVRVIlKRLLSEHENARFVVTGHSLGGALAILFptllVLNEETEIMKRLLGVYTFGQPRIGNrevgLFMKAQLNQPVDR 394
Cdd:PLN02310 194 EVKRLV-NFYRGKGEEVSLTVTGHSLGGALALLN----AYEAATTIPDLFVSVISFGAPRVGN----IAFKEKLNELGVK 264

                        170       180
                 ....*....|....*....|....*...
gi 42564151  395 YFRVVYCNDIVPRLPYDDKTFLYKHFGL 422
Cdd:PLN02310 265 TLRVVVKQDKVPKLPGLLNKMLNKFHGL 292
PLN02324 PLN02324
triacylglycerol lipase
 235-421 1.37e-09

triacylglycerol lipase


Pssm-ID: 177958  Cd Length: 415  Bit Score: 60.03  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  235 IVISFRGT-EPFDaddWGTDFDY------SWYEV------PNVGKlhmGFLEAMglgnrddTTTFHYNLFEQTSSEEEns 301
Cdd:PLN02324 134 IVVAWRGTlQPYE---WANDFDFplesaiSVFPVtdpkdnPRIGS---GWLDIY-------TASDSRSPYDTTSAQEQ-- 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  302 kknlldmversayyaVRVILKRLLSEHENARFVVT--GHSLGGALAILFPTLLVLNEETEIMKRL------LGVYTFGQP 373
Cdd:PLN02324 199 ---------------VQGELKRLLELYKNEEISITftGHSLGAVMSVLSAADLVYGKKNKINISLqkkqvpITVFAFGSP 263

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 42564151  374 RIGNREVGLFMKAQlnQPVDrYFRVVYCNDIVPRLPyddkTFLYKHFG 421
Cdd:PLN02324 264 RIGDHNFKNLVDSL--QPLN-ILRIVNVPDVAPHYP----LLLYTEIG 304
PLN02802 PLN02802
triacylglycerol lipase
 322-428 6.50e-09

triacylglycerol lipase


Pssm-ID: 215432  Cd Length: 509  Bit Score: 58.24  E-value: 6.50e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  322 KRLLS--EHENARFVVTGHSLGGALAilfptLLVLNEETEIMKRL--LGVYTFGQPRIGNREvglfMKAQLNQPVDRYFR 397
Cdd:PLN02802 319 RRLMEkyKGEELSITVTGHSLGAALA-----LLVADELATCVPAAppVAVFSFGGPRVGNRA----FADRLNARGVKVLR 389

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 42564151  398 VVYCNDIVPRLP-----YDDKTFLYKHFGLCLFYDS 428
Cdd:PLN02802 390 VVNAQDVVTRVPgiaprEELHKWAYAHVGAELRLDS 425
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 300-409 1.26e-08

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 57.27  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  300 NSKKNLLDMVERSAYYAVRVILKRLLS----EHENARFVVTGHSLGGALAilfptLLVLNEETEIMKRL--LGVYTFGQP 373
Cdd:PLN03037 283 KSKSELTRYNKLSASEQVMEEVKRLVNffkdRGEEVSLTITGHSLGGALA-----LLNAYEAARSVPALsnISVISFGAP 357

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 42564151  374 RIGNrevgLFMKAQLNQPVDRYFRVVYCNDIVPRLP 409
Cdd:PLN03037 358 RVGN----LAFKEKLNELGVKVLRVVNKQDIVPKLP 389
PLN02408 PLN02408
phospholipase A1
 218-409 4.24e-07

phospholipase A1


Pssm-ID: 215228  Cd Length: 365  Bit Score: 52.15  E-value: 4.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  218 MSTQ------VFVFTDKQKDANL----IVISFRGTEpfDADDWGTDFDYSWYEVPNvgklhmgfleamglgnrddtttfh 287
Cdd:PLN02408  93 VATQsswigyVAVCQDKEEIARLgrrdVVIAFRGTA--TCLEWLENLRATLTRLPN------------------------ 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  288 ynlfeqTSSEEENSKKNLLDMVER---SAYYA-----------VRVILKRLLSEH--ENARFVVTGHSLGGALAILFPTL 351
Cdd:PLN02408 147 ------APTDMNGSGDGSGPMVESgflSLYTSgtamgpslqemVREEIARLLQSYgdEPLSLTITGHSLGAALATLTAYD 220

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 42564151  352 LvlnEETEIMKRLLGVYTFGQPRIGNREvglfMKAQLNQPVDRYFRVVYCNDIVPRLP 409
Cdd:PLN02408 221 I---KTTFKRAPMVTVISFGGPRVGNRS----FRRQLEKQGTKVLRIVNSDDVITKVP 271
PLN02761 PLN02761
lipase class 3 family protein
 211-420 1.12e-06

lipase class 3 family protein


Pssm-ID: 215406 [Multi-domain]  Cd Length: 527  Bit Score: 51.20  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  211 WNDYQKQMSTqVFVFTDKQKDANL----IVISFRGTEPFDadDWGTDF-----DYSWYEVPNVgKLHMGFleamglgnrd 281
Cdd:PLN02761 187 WSQHANWMGY-VAVATDEEEVKRLgrrdIVIAWRGTVTYL--EWIYDLkdilcSANFGDDPSI-KIELGF---------- 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  282 dtttfhYNLFeqtsSEEENSKKnlldMVERSAYYAVRVILKRLL------SEHENARFVVTGHSLGGALAILFP---TLL 352
Cdd:PLN02761 253 ------HDLY----TKKEDSCK----FSSFSAREQVLAEVKRLVeyygteEEGHEISITVTGHSLGASLALVSAydiAEL 318

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42564151  353 VLNEETEIMKRL-LGVYTFGQPRIGNrevgLFMKAQLNQPVDRYFRVVYCNDIVPRLP--YDDKTFLYKHF 420
Cdd:PLN02761 319 NLNHVPENNYKIpITVFSFSGPRVGN----LRFKERCDELGVKVLRVVNVHDKVPSVPgiFTNEKFQFQKY 385
PLN02571 PLN02571
triacylglycerol lipase
 235-409 5.44e-05

triacylglycerol lipase


Pssm-ID: 215309  Cd Length: 413  Bit Score: 45.65  E-value: 5.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  235 IVISFRGT-EPFDaddWGTDFDYSWYEVPNVgklhmgfleamgLGNRDDTTTFH---YNLFEQTSSEEENSKKNLLDMVE 310
Cdd:PLN02571 147 IVIAWRGTvQTLE---WVNDFEFNLVSASKI------------FGESNDQPKVHqgwYSIYTSDDERSPFNKTSARDQVL 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  311 RSayyavrviLKRLLSEHENARFVVT--GHSLGGALAILFPTLLVLNEETEIMKRL-----LGVYTFGQPRIGNREvglF 383
Cdd:PLN02571 212 NE--------VGRLVEKYKDEEISITicGHSLGAALATLNAVDIVANGFNRSKSRPnkscpVTAFVFASPRVGDSD---F 280

                        170       180
                 ....*....|....*....|....*.
gi 42564151  384 MKAQLNQPVDRYFRVVYCNDIVPRLP 409
Cdd:PLN02571 281 KKLFSGLKDLRVLRVRNLPDVIPNYP 306
PLN02454 PLN02454
triacylglycerol lipase
 321-458 1.55e-04

triacylglycerol lipase


Pssm-ID: 215249  Cd Length: 414  Bit Score: 44.06  E-value: 1.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  321 LKRLLSEH--ENARFVVTGHSLGGALAILFPTLLVLNeETEIMKRLLGVYTFGQPRIGNREvglFMKAQLNQPVDRYFRV 398
Cdd:PLN02454 216 IKELLERYkdEKLSIVLTGHSLGASLATLAAFDIVEN-GVSGADIPVTAIVFGSPQVGNKE---FNDRFKEHPNLKILHV 291

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  399 VYCNDIVPRLPydDKTFLYKHFGLCLFYDSfYNETKAEDEPDPNPYGLRYKILgHVIAVW 458
Cdd:PLN02454 292 RNTIDLIPHYP--GGLLGYVNTGTELVIDT-RKSPFLKDSKNPGDWHNLQAML-HVVAGW 347
PLN02753 PLN02753
triacylglycerol lipase
 312-409 3.67e-04

triacylglycerol lipase


Pssm-ID: 178354  Cd Length: 531  Bit Score: 43.16  E-value: 3.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  312 SAYYAVRVILKRLLS-----EHENARFVVTGHSLGGALAILFPTLLV---LNEETEIMKRLLGVYTFGQPRIGNrevgLF 383
Cdd:PLN02753 288 SAREQILTEVKRLVEehgddDDSDLSITVTGHSLGGALAILSAYDIAemgLNRSKKGKVIPVTVLTYGGPRVGN----VR 363

                         90       100
                 ....*....|....*....|....*.
gi 42564151  384 MKAQLNQPVDRYFRVVYCNDIVPRLP 409
Cdd:PLN02753 364 FKDRMEELGVKVLRVVNVHDVVPKSP 389
PLN02719 PLN02719
triacylglycerol lipase
 312-409 4.05e-04

triacylglycerol lipase


Pssm-ID: 178321  Cd Length: 518  Bit Score: 43.15  E-value: 4.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42564151  312 SAYYAVRVILKRLLS-----EHENARFVVTGHSLGGALAILFP---TLLVLNEETEIMKRLLGVYTFGQPRIGNrevgLF 383
Cdd:PLN02719 274 SAREQVLTEVKRLVErygdeEGEELSITVTGHSLGGALAVLSAydvAEMGLNRTRKGKVIPVTAFTYGGPRVGN----IR 349

                         90       100
                 ....*....|....*....|....*.
gi 42564151  384 MKAQLNQPVDRYFRVVYCNDIVPRLP 409
Cdd:PLN02719 350 FKERIEELGVKVLRVVNEHDVVAKSP 375
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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