NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|18407449|ref|NP_566111|]
View 

Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
56-260 3.65e-17

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 82.27  E-value: 3.65e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  56 IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVSRIdTGNDQEIFS 135
Cdd:COG2319 177 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDG----KLLASGSADGTVRLWDLATGKLLRTL-TGHSGSVRS 251

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 136 --FSYGGAAdnLLAGGCKEQVLLWDWRNSKQVACLeESHMDDVTQVHFVPNkPNKLLSASVDGLICLFntegDINDDDHL 213
Cdd:COG2319 252 vaFSPDGRL--LASGSADGTVRLWDLATGELLRTL-TGHSGGVNSVAFSPD-GKLLASGSDDGTVRLW----DLATGKLL 323

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 18407449 214 ESVINVGTSIGKIGFLGDGyKKLWCLTHIETLSIWNWEDGSCEVNLE 260
Cdd:COG2319 324 RTLTGHTGAVRSVAFSPDG-KTLASGSDDGTVRLWDLATGELLRTLT 369
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
56-260 3.65e-17

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 82.27  E-value: 3.65e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  56 IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVSRIdTGNDQEIFS 135
Cdd:COG2319 177 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDG----KLLASGSADGTVRLWDLATGKLLRTL-TGHSGSVRS 251

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 136 --FSYGGAAdnLLAGGCKEQVLLWDWRNSKQVACLeESHMDDVTQVHFVPNkPNKLLSASVDGLICLFntegDINDDDHL 213
Cdd:COG2319 252 vaFSPDGRL--LASGSADGTVRLWDLATGELLRTL-TGHSGGVNSVAFSPD-GKLLASGSDDGTVRLW----DLATGKLL 323

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 18407449 214 ESVINVGTSIGKIGFLGDGyKKLWCLTHIETLSIWNWEDGSCEVNLE 260
Cdd:COG2319 324 RTLTGHTGAVRSVAFSPDG-KTLASGSDDGTVRLWDLATGELLRTLT 369
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 41-202 1.57e-14

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 73.52  E-value: 1.57e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  41 SDYVFQIVPKIDWTAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSAaspHVLhSCSSDGTIRSWDTRSFQ 120
Cdd:cd00200 135 TDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGE---KLL-SSSSDGTIKLWDLSTGK 210

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 121 QVSRIdTGNDQEIFSFSYGGAADNLLAGGCKEQVLLWDWRNSKQVACLEEsHMDDVTQVHFVPNKpNKLLSASVDGLICL 200
Cdd:cd00200 211 CLGTL-RGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSG-HTNSVTSLAWSPDG-KRLASGSADGTIRI 287


                ..
gi 18407449 201 FN 202
Cdd:cd00200 288 WD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 54-202 5.25e-06

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 48.54  E-value: 5.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449   54 TAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSdsaASPHVLHSCSSDGTIRSWDTRSFQQVSRIDTGNDQEI 133
Cdd:PLN00181 546 SQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSS---ADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICC 622

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18407449  134 FSFSyGGAADNLLAGGCKEQVLLWDWRNSKQVACLEESHMDDVTQVHFVPNkpNKLLSASVDGLICLFN 202
Cdd:PLN00181 623 VQFP-SESGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDS--STLVSSSTDNTLKLWD 688
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 72-115 3.33e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 40.76  E-value: 3.33e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 18407449     72 TGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWD 115
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDG----KYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
73-115 1.51e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.87  E-value: 1.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 18407449    73 GQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWD 115
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDG----KLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
56-260 3.65e-17

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 82.27  E-value: 3.65e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  56 IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVSRIdTGNDQEIFS 135
Cdd:COG2319 177 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDG----KLLASGSADGTVRLWDLATGKLLRTL-TGHSGSVRS 251

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 136 --FSYGGAAdnLLAGGCKEQVLLWDWRNSKQVACLeESHMDDVTQVHFVPNkPNKLLSASVDGLICLFntegDINDDDHL 213
Cdd:COG2319 252 vaFSPDGRL--LASGSADGTVRLWDLATGELLRTL-TGHSGGVNSVAFSPD-GKLLASGSDDGTVRLW----DLATGKLL 323

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 18407449 214 ESVINVGTSIGKIGFLGDGyKKLWCLTHIETLSIWNWEDGSCEVNLE 260
Cdd:COG2319 324 RTLTGHTGAVRSVAFSPDG-KTLASGSDDGTVRLWDLATGELLRTLT 369
WD40 COG2319
WD40 repeat [General function prediction only];
56-205 5.05e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 5.05e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  56 IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVSRIdTGNDQEIFS 135
Cdd:COG2319 261 LASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDG----KLLASGSDDGTVRLWDLATGKLLRTL-TGHTGAVRS 335

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18407449 136 --FSYGGAAdnLLAGGCKEQVLLWDWRNSKQVACLEEsHMDDVTQVHFVPNKpNKLLSASVDGLICLFNTEG 205
Cdd:COG2319 336 vaFSPDGKT--LASGSDDGTVRLWDLATGELLRTLTG-HTGAVTSVAFSPDG-RTLASGSADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
40-205 1.58e-15

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 77.64  E-value: 1.58e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  40 GSDYVFQIVPKIDWTAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSF 119
Cdd:COG2319  77 HTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDG----KTLASGSADGTVRLWDLATG 152

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 120 QQVSRIdTGNDQEIFSFSYGGAADNLLAGGCKEQVLLWDWRNSKQVACLEEsHMDDVTQVHFVPNKpNKLLSASVDGLIC 199
Cdd:COG2319 153 KLLRTL-TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTG-HTGAVRSVAFSPDG-KLLASGSADGTVR 229


                ....*.
gi 18407449 200 LFNTEG 205
Cdd:COG2319 230 LWDLAT 235
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 41-202 1.57e-14

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 73.52  E-value: 1.57e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  41 SDYVFQIVPKIDWTAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSAaspHVLhSCSSDGTIRSWDTRSFQ 120
Cdd:cd00200 135 TDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGE---KLL-SSSSDGTIKLWDLSTGK 210

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 121 QVSRIdTGNDQEIFSFSYGGAADNLLAGGCKEQVLLWDWRNSKQVACLEEsHMDDVTQVHFVPNKpNKLLSASVDGLICL 200
Cdd:cd00200 211 CLGTL-RGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSG-HTNSVTSLAWSPDG-KRLASGSADGTIRI 287


                ..
gi 18407449 201 FN 202
Cdd:cd00200 288 WD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 56-204 1.83e-14

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 73.14  E-value: 1.83e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  56 IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVSRIdTGNDQEIFS 135
Cdd:cd00200  24 LATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADG----TYLASGSSDKTIRLWDLETGECVRTL-TGHTSYVSS 98

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 136 FSYGGAADNLLAGGCKEQVLLWDWRNSKQVACLeESHMDDVTQVHFVPNkpNKLL-SASVDGLICLFNTE 204
Cdd:cd00200  99 VAFSPDGRILSSSSRDKTIKVWDVETGKCLTTL-RGHTDWVNSVAFSPD--GTFVaSSSQDGTIKLWDLR 165
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 48-255 2.60e-13

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 69.67  E-value: 2.60e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  48 VPKIDWTA----IAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSFQQVS 123
Cdd:cd00200  54 VRDVAASAdgtyLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDG----RILSSSSRDKTIKVWDVETGKCLT 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 124 RIdTGNDQEIFSFSYGGaADNLLAGGCKE-QVLLWDWRNSKQVACLeESHMDDVTQVHFVPNKpNKLLSASVDGLICLFn 202
Cdd:cd00200 130 TL-RGHTDWVNSVAFSP-DGTFVASSSQDgTIKLWDLRTGKCVATL-TGHTGEVNSVAFSPDG-EKLLSSSSDGTIKLW- 204

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 18407449 203 tegDINDDDHLESVINVGTSIGKIGFLGDGYkklWCL--THIETLSIWNWEDGSC 255
Cdd:cd00200 205 ---DLSTGKCLGTLRGHENGVNSVAFSPDGY---LLAsgSEDGTIRVWDLRTGEC 253
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 76-204 1.46e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 64.66  E-value: 1.46e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  76 YGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWDTRSfQQVSRIDTGNDQEIFSFSYGGAADNLLAGGCKEQVL 155
Cdd:cd00200   2 RRTLKGHTGGVTCVAFSPDG----KLLATGSGDGTIKVWDLET-GELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIR 76

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 18407449 156 LWDWRNSKQVACLeESHMDDVTQVHFVPNKPnKLLSASVDGLICLFNTE 204
Cdd:cd00200  77 LWDLETGECVRTL-TGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVE 123
WD40 COG2319
WD40 repeat [General function prediction only];
52-260 3.03e-09

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.38  E-value: 3.03e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449  52 DWTAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDsaasPHVLHSCSSDGTIRSWDTRSfQQVSRIDTGNDQ 131
Cdd:COG2319  47 DGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPD----GRLLASASADGTVRLWDLAT-GLLLRTLTGHTG 121

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449 132 EIFS--FSYGGAAdnLLAGGCKEQVLLWDWRNSKQVACLEEsHMDDVTQVHFVPNKpNKLLSASVDGLICLFntegDIND 209
Cdd:COG2319 122 AVRSvaFSPDGKT--LASGSADGTVRLWDLATGKLLRTLTG-HSGAVTSVAFSPDG-KLLASGSDDGTVRLW----DLAT 193

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 18407449 210 DDHLESVINVGTSIGKIGFLGDGyKKLWCLTHIETLSIWNWEDGSCEVNLE 260
Cdd:COG2319 194 GKLLRTLTGHTGAVRSVAFSPDG-KLLASGSADGTVRLWDLATGKLLRTLT 243
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 54-202 5.25e-06

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 48.54  E-value: 5.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407449   54 TAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSdsaASPHVLHSCSSDGTIRSWDTRSFQQVSRIDTGNDQEI 133
Cdd:PLN00181 546 SQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSS---ADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICC 622

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18407449  134 FSFSyGGAADNLLAGGCKEQVLLWDWRNSKQVACLEESHMDDVTQVHFVPNkpNKLLSASVDGLICLFN 202
Cdd:PLN00181 623 VQFP-SESGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDS--STLVSSSTDNTLKLWD 688
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 72-115 3.33e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 40.76  E-value: 3.33e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 18407449     72 TGQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWD 115
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDG----KYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
73-115 1.51e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.87  E-value: 1.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 18407449    73 GQYYGECKGHSDTVNQIAFSSDSaaspHVLHSCSSDGTIRSWD 115
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDG----KLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH