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Conserved domains on  [gi|18403957|ref|NP_565824|]
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Chaperone DnaJ-domain superfamily protein [Arabidopsis thaliana]

Protein Classification

J domain-containing protein( domain architecture ID 84)

J domain-containing protein similar to molecular chaperone DnaJ, a protein that plays crucial roles in protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of Hsp70

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
SCOP:  4000605

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DnaJ super family cl02542
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
1-103 2.92e-23

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


The actual alignment was detected with superfamily member PTZ00100:

Pssm-ID: 413365  Cd Length: 116  Bit Score: 86.44  E-value: 2.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18403957    1 MATPFIAgVAVAATALAGRYGIQAWQAFKARPPR----------PKIKKFYEG----GFQPTMTKREAALILGVRESVAA 66
Cdd:PTZ00100   1 MMWPIVA-LTFGGGVLAVRYGYRYLKNQKIFGSNnmsfplsgfnPSLGSLFLKndlkGFENPMSKSEAYKILNISPTASK 79
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 18403957   67 EKVKEAHRKVMVANHPDAGGSHFLASKINEAKDVMLG 103
Cdd:PTZ00100  80 ERIREAHKQLMLRNHPDNGGSTYIASKVNEAKDLLLK 116
 
Name Accession Description Interval E-value
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
1-103 2.92e-23

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 86.44  E-value: 2.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18403957    1 MATPFIAgVAVAATALAGRYGIQAWQAFKARPPR----------PKIKKFYEG----GFQPTMTKREAALILGVRESVAA 66
Cdd:PTZ00100   1 MMWPIVA-LTFGGGVLAVRYGYRYLKNQKIFGSNnmsfplsgfnPSLGSLFLKndlkGFENPMSKSEAYKILNISPTASK 79
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 18403957   67 EKVKEAHRKVMVANHPDAGGSHFLASKINEAKDVMLG 103
Cdd:PTZ00100  80 ERIREAHKQLMLRNHPDNGGSTYIASKVNEAKDLLLK 116
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
57-100 4.36e-06

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 40.61  E-value: 4.36e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLA----SKINEAKDV 100
Cdd:cd06257   5 ILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAeekfKEINEAYEV 52
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
57-100 2.22e-05

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 39.70  E-value: 2.22e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHF-----LASKINEAKDV 100
Cdd:COG2214  10 VLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKalaeeLFQRLNEAYEV 58
DnaJ smart00271
DnaJ molecular chaperone homology domain;
57-101 3.75e-05

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 38.37  E-value: 3.75e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 18403957     57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLAS-----KINEAKDVM 101
Cdd:smart00271   6 ILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAeekfkEINEAYEVL 55
 
Name Accession Description Interval E-value
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
1-103 2.92e-23

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 86.44  E-value: 2.92e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18403957    1 MATPFIAgVAVAATALAGRYGIQAWQAFKARPPR----------PKIKKFYEG----GFQPTMTKREAALILGVRESVAA 66
Cdd:PTZ00100   1 MMWPIVA-LTFGGGVLAVRYGYRYLKNQKIFGSNnmsfplsgfnPSLGSLFLKndlkGFENPMSKSEAYKILNISPTASK 79
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 18403957   67 EKVKEAHRKVMVANHPDAGGSHFLASKINEAKDVMLG 103
Cdd:PTZ00100  80 ERIREAHKQLMLRNHPDNGGSTYIASKVNEAKDLLLK 116
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
49-106 3.19e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 44.17  E-value: 3.19e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18403957   49 MTKREAALILGVRESVAAEKVKEAHRKVMVANHPD---AGGSHFLASKINEAKDVMLGKTK 106
Cdd:PRK14296   1 MKKKDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDlnkSPDAHDKMVEINEAADVLLDKDK 61
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
57-100 4.36e-06

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 40.61  E-value: 4.36e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLA----SKINEAKDV 100
Cdd:cd06257   5 ILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAeekfKEINEAYEV 52
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
57-100 2.22e-05

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 39.70  E-value: 2.22e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHF-----LASKINEAKDV 100
Cdd:COG2214  10 VLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKalaeeLFQRLNEAYEV 58
DnaJ smart00271
DnaJ molecular chaperone homology domain;
57-101 3.75e-05

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 38.37  E-value: 3.75e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 18403957     57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLAS-----KINEAKDVM 101
Cdd:smart00271   6 ILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAeekfkEINEAYEVL 55
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
49-99 5.11e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 37.68  E-value: 5.11e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 18403957   49 MTKREAALILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLASKINEAKD 99
Cdd:PRK14287   1 MSKRDYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKAPDAEDKFKEVKE 51
PRK14279 PRK14279
molecular chaperone DnaJ;
49-106 7.81e-04

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 37.40  E-value: 7.81e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18403957   49 MTKREAA-----LILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLAS----KINEAKDVMLGKTK 106
Cdd:PRK14279   1 MAQREWVekdfyKELGVSSDASAEEIKKAYRKLARELHPDANPGDPAAEerfkAVSEAHDVLSDPAK 67
djlA PRK09430
co-chaperone DjlA;
57-83 1.43e-03

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 36.33  E-value: 1.43e-03
                         10        20
                 ....*....|....*....|....*..
gi 18403957   57 ILGVRESVAAEKVKEAHRKVMVANHPD 83
Cdd:PRK09430 205 VLGVSESDDDQEIKRAYRKLMSEHHPD 231
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
50-101 1.64e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 36.32  E-value: 1.64e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 18403957   50 TKREAALILGVRESVAAEKVKEAHRKVMVANHPDA------GGSHFlaSKINEAKDVM 101
Cdd:PRK14281   1 MKRDYYEVLGVSRSADKDEIKKAYRKLALKYHPDKnpdnkeAEEHF--KEVNEAYEVL 56
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
49-83 1.69e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 36.28  E-value: 1.69e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 18403957   49 MTKREAALILGVRESVAAEKVKEAHRKVMVANHPD 83
Cdd:PRK14294   1 MVKRDYYEILGVTRDASEEEIKKSYRKLAMKYHPD 35
PRK14295 PRK14295
molecular chaperone DnaJ;
57-106 2.23e-03

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 35.98  E-value: 2.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 18403957   57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLASK----INEAKDVmLGKTK 106
Cdd:PRK14295  14 VLGVPKDATEAEIKKAYRKLAREYHPDANKGDAKAEErfkeISEAYDV-LSDEK 66
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
49-83 3.99e-03

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 35.10  E-value: 3.99e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 18403957   49 MTKREAALILGVRESVAAEKVKEAHRKVMVANHPD 83
Cdd:PRK14301   1 MSQRDYYEVLGVSRDASEDEIKKAYRKLALQYHPD 35
PRK14280 PRK14280
molecular chaperone DnaJ;
49-83 4.77e-03

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 35.08  E-value: 4.77e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 18403957   49 MTKREAALILGVRESVAAEKVKEAHRKVMVANHPD 83
Cdd:PRK14280   1 MAKRDYYEVLGVSKSASKDEIKKAYRKLSKKYHPD 35
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
57-106 5.05e-03

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 33.05  E-value: 5.05e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLA----SKINEAKDVMLGKTK 106
Cdd:COG5407   5 VLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPKAeerfKEINEAYELLSDAEK 58
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
57-100 5.44e-03

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 34.29  E-value: 5.44e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 18403957  57 ILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLA----SKINEAKDV 100
Cdd:COG0484   5 ILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAeekfKEINEAYEV 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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