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Conserved domains on  [gi|18409228|ref|NP_564956|]
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ABI five binding protein [Arabidopsis thaliana]

Protein Classification

N-acetyltransferase( domain architecture ID 11171851)

N-acetyltransferase catalyzes the transfer of the acetyl group from acetyl coenzyme A donor to a substrate; contains Jas domain(s) which in plant transcriptional repressors bind Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins (TPRs), and plant homeodomain (PHD) finger(s) which bind zinc and may be involved in protein-protein interaction

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NINJA_B pfam16136
Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins ...
 110-223 1.56e-36

Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins found in plants. NINJA proteins act as a transcriptional repressor, the activity of which is mediated by a functional TPL-binding EAR repression motif upstream from this domain.


:

Pssm-ID: 406525  Cd Length: 114  Bit Score: 127.96  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18409228   110 LMRTTSLPAESEEEWRKRKEMQTLRRMAAKRRRSEKLRTGV-GGGNSNNPEEAATATASRRRGRPSSGLPRWSAtANKSG 188
Cdd:pfam16136   1 LMRTTSLPTETEEEWRKRKEMQTLRRMEAKRRRSEKQRNGNsGGGNVSKEKEANNSTVSRRRGRPSSGLPRWSA-ANKAG 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 18409228   189 LLRQHSaGLDSLQVSGESLGGGRAAGSSSSVSELE 223
Cdd:pfam16136  80 LLRRHD-GLQNMYGQQSQGSVESQGGSSSGMSELE 113
EAR pfam07897
Ethylene-responsive binding factor-associated repression; The EAR motif is the ...
 46-74 2.11e-08

Ethylene-responsive binding factor-associated repression; The EAR motif is the ethylene-responsive element binding factor-associated amphiphilic repression motif. This motif binds to the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins. The motif is frequently to be find at the N-terminus of NINJA, or Novel INteractor of JAZ, proteins. The EAR motif, defined by the consensus sequence patterns of either LxLxL or DLN xxP, is the most predominant form of transcriptional repression motif so far identified in plants. It is highly conserved in transcriptional regulators that are known to function as negative regulators in a broad range of developmental and physiological processes across evolutionarily diverse plant species. This family is closely related to family AUX_IAA Pam:PF02309 which also has an LxLxL signature.


:

Pssm-ID: 462309  Cd Length: 35  Bit Score: 49.50  E-value: 2.11e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 18409228    46 IELNLGLSLGGRFGVD-KSNKLVRSSSVVV 74
Cdd:pfam07897   6 IELSLGLSLGGRFGVDpKRKKLPRSSSIAS 35
TDBD pfam16135
Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from ...
 304-334 2.95e-06

Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from the NINJA protein which interacts with the Tify domain of JAZ1.


:

Pssm-ID: 465033  Cd Length: 52  Bit Score: 43.84  E-value: 2.95e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 18409228   304 IMCVCHGDFLSPADFVKHAGGpHVDHPLRHI 334
Cdd:pfam16135   8 ILCSCCGKVFSPSEFEAHAGS-KNRRPSANI 37
 
Name Accession Description Interval E-value
NINJA_B pfam16136
Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins ...
 110-223 1.56e-36

Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins found in plants. NINJA proteins act as a transcriptional repressor, the activity of which is mediated by a functional TPL-binding EAR repression motif upstream from this domain.


Pssm-ID: 406525  Cd Length: 114  Bit Score: 127.96  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18409228   110 LMRTTSLPAESEEEWRKRKEMQTLRRMAAKRRRSEKLRTGV-GGGNSNNPEEAATATASRRRGRPSSGLPRWSAtANKSG 188
Cdd:pfam16136   1 LMRTTSLPTETEEEWRKRKEMQTLRRMEAKRRRSEKQRNGNsGGGNVSKEKEANNSTVSRRRGRPSSGLPRWSA-ANKAG 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 18409228   189 LLRQHSaGLDSLQVSGESLGGGRAAGSSSSVSELE 223
Cdd:pfam16136  80 LLRRHD-GLQNMYGQQSQGSVESQGGSSSGMSELE 113
EAR pfam07897
Ethylene-responsive binding factor-associated repression; The EAR motif is the ...
 46-74 2.11e-08

Ethylene-responsive binding factor-associated repression; The EAR motif is the ethylene-responsive element binding factor-associated amphiphilic repression motif. This motif binds to the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins. The motif is frequently to be find at the N-terminus of NINJA, or Novel INteractor of JAZ, proteins. The EAR motif, defined by the consensus sequence patterns of either LxLxL or DLN xxP, is the most predominant form of transcriptional repression motif so far identified in plants. It is highly conserved in transcriptional regulators that are known to function as negative regulators in a broad range of developmental and physiological processes across evolutionarily diverse plant species. This family is closely related to family AUX_IAA Pam:PF02309 which also has an LxLxL signature.


Pssm-ID: 462309  Cd Length: 35  Bit Score: 49.50  E-value: 2.11e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 18409228    46 IELNLGLSLGGRFGVD-KSNKLVRSSSVVV 74
Cdd:pfam07897   6 IELSLGLSLGGRFGVDpKRKKLPRSSSIAS 35
TDBD pfam16135
Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from ...
 304-334 2.95e-06

Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from the NINJA protein which interacts with the Tify domain of JAZ1.


Pssm-ID: 465033  Cd Length: 52  Bit Score: 43.84  E-value: 2.95e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 18409228   304 IMCVCHGDFLSPADFVKHAGGpHVDHPLRHI 334
Cdd:pfam16135   8 ILCSCCGKVFSPSEFEAHAGS-KNRRPSANI 37
 
Name Accession Description Interval E-value
NINJA_B pfam16136
Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins ...
 110-223 1.56e-36

Putative nuclear localization signal; NINJA proteins are Novel INteractor of JAZ proteins found in plants. NINJA proteins act as a transcriptional repressor, the activity of which is mediated by a functional TPL-binding EAR repression motif upstream from this domain.


Pssm-ID: 406525  Cd Length: 114  Bit Score: 127.96  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18409228   110 LMRTTSLPAESEEEWRKRKEMQTLRRMAAKRRRSEKLRTGV-GGGNSNNPEEAATATASRRRGRPSSGLPRWSAtANKSG 188
Cdd:pfam16136   1 LMRTTSLPTETEEEWRKRKEMQTLRRMEAKRRRSEKQRNGNsGGGNVSKEKEANNSTVSRRRGRPSSGLPRWSA-ANKAG 79

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 18409228   189 LLRQHSaGLDSLQVSGESLGGGRAAGSSSSVSELE 223
Cdd:pfam16136  80 LLRRHD-GLQNMYGQQSQGSVESQGGSSSGMSELE 113
EAR pfam07897
Ethylene-responsive binding factor-associated repression; The EAR motif is the ...
 46-74 2.11e-08

Ethylene-responsive binding factor-associated repression; The EAR motif is the ethylene-responsive element binding factor-associated amphiphilic repression motif. This motif binds to the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins. The motif is frequently to be find at the N-terminus of NINJA, or Novel INteractor of JAZ, proteins. The EAR motif, defined by the consensus sequence patterns of either LxLxL or DLN xxP, is the most predominant form of transcriptional repression motif so far identified in plants. It is highly conserved in transcriptional regulators that are known to function as negative regulators in a broad range of developmental and physiological processes across evolutionarily diverse plant species. This family is closely related to family AUX_IAA Pam:PF02309 which also has an LxLxL signature.


Pssm-ID: 462309  Cd Length: 35  Bit Score: 49.50  E-value: 2.11e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 18409228    46 IELNLGLSLGGRFGVD-KSNKLVRSSSVVV 74
Cdd:pfam07897   6 IELSLGLSLGGRFGVDpKRKKLPRSSSIAS 35
TDBD pfam16135
Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from ...
 304-334 2.95e-06

Tify domain binding domain; This entry contains a C-terminal presumed zinc binding domain from the NINJA protein which interacts with the Tify domain of JAZ1.


Pssm-ID: 465033  Cd Length: 52  Bit Score: 43.84  E-value: 2.95e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 18409228   304 IMCVCHGDFLSPADFVKHAGGpHVDHPLRHI 334
Cdd:pfam16135   8 ILCSCCGKVFSPSEFEAHAGS-KNRRPSANI 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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