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Conserved domains on  [gi|18408874|ref|NP_564908|]
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chloroplast sensor kinase [Arabidopsis thaliana]

Protein Classification

histidine kinase( domain architecture ID 1903468)

histidine kinase may contain a sensor domain and be part of a two-component regulatory system, to function as a protein kinase that phosphorylates a target protein in response to a specific signal

EC:  2.7.13.3
PubMed:  10339418
SCOP:  4001957

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
KdpD super family cl43644
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
437-603 1.49e-09

K+-sensing histidine kinase KdpD [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG2205:

Pssm-ID: 441807 [Multi-domain]  Cd Length: 239  Bit Score: 58.76  E-value: 1.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 437 SIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGS 516
Cdd:COG2205  87 ELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITI-SARREGDGV 165
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 517 LVVIDDDGPDM----------RYMTQMHSLTPFGAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISPrssdaa 586
Cdd:COG2205 166 RISVSDNGPGIpeeelerifeRFYRGDNSRGEGGTGL----------------GLAIVKRIVEAHGGTIWVESE------ 223
                       170
                ....*....|....*..
gi 18408874 587 lGAGGTRVELWLPAFPA 603
Cdd:COG2205 224 -PGGGTTFTVTLPLAES 239
 
Name Accession Description Interval E-value
KdpD COG2205
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
437-603 1.49e-09

K+-sensing histidine kinase KdpD [Signal transduction mechanisms];


Pssm-ID: 441807 [Multi-domain]  Cd Length: 239  Bit Score: 58.76  E-value: 1.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 437 SIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGS 516
Cdd:COG2205  87 ELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITI-SARREGDGV 165
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 517 LVVIDDDGPDM----------RYMTQMHSLTPFGAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISPrssdaa 586
Cdd:COG2205 166 RISVSDNGPGIpeeelerifeRFYRGDNSRGEGGTGL----------------GLAIVKRIVEAHGGTIWVESE------ 223
                       170
                ....*....|....*..
gi 18408874 587 lGAGGTRVELWLPAFPA 603
Cdd:COG2205 224 -PGGGTTFTVTLPLAES 239
HATPase_c pfam02518
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
480-599 3.52e-06

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.


Pssm-ID: 460579 [Multi-domain]  Cd Length: 109  Bit Score: 46.21  E-value: 3.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874   480 EPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGSLVVIdDDGPDMRYMTQMHSLTPFGaellsenMVEDNMTWNFVA 559
Cdd:pfam02518   3 ELRLRQVLSNLLDNALKHAAKAGEITV-TLSEGGELTLTVE-DNGIGIPPEDLPRIFEPFS-------TADKRGGGGTGL 73
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 18408874   560 GLTVAREILESYGCVIRVISPRSsdaalgaGGTRVELWLP 599
Cdd:pfam02518  74 GLSIVRKLVELLGGTITVESEPG-------GGTTVTLTLP 106
HATPase_c smart00387
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
480-599 1.54e-05

Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.


Pssm-ID: 214643 [Multi-domain]  Cd Length: 111  Bit Score: 44.18  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874    480 EPALRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVVIdDDGPDMRYMTQMHSLTPFGAELLSENMVEdnmtwNFVA 559
Cdd:smart00387   3 PDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVE-DNGPGIPPEDLEKIFEPFFRTDKRSRKIG-----GTGL 76
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 18408874    560 GLTVAREILESYGCVIRVISPRSsdaalgaGGTRVELWLP 599
Cdd:smart00387  77 GLSIVKKLVELHGGEISVESEPG-------GGTTFTITLP 109
PRK11100 PRK11100
sensory histidine kinase CreC; Provisional
428-525 5.35e-05

sensory histidine kinase CreC; Provisional


Pssm-ID: 236846 [Multi-domain]  Cd Length: 475  Bit Score: 45.99  E-value: 5.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874  428 LALAPL-QMHSIR---PCDISNVLLDMVETVRPLAltQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGK 503
Cdd:PRK11100 312 LELARLeQRQELEvlePVALAALLEELVEAREAQA--AAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGT 389
                         90       100
                 ....*....|....*....|..
gi 18408874  504 VEiLSTRAPAGGSLVVIDDDGP 525
Cdd:PRK11100 390 IT-LSAEVDGEQVALSVEDQGP 410
HATPase_BaeS-like cd16946
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ...
483-525 5.45e-04

Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.


Pssm-ID: 340422 [Multi-domain]  Cd Length: 109  Bit Score: 39.75  E-value: 5.45e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 18408874 483 LRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVViDDDGP 525
Cdd:cd16946   5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDV-EDSAP 46
 
Name Accession Description Interval E-value
KdpD COG2205
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
437-603 1.49e-09

K+-sensing histidine kinase KdpD [Signal transduction mechanisms];


Pssm-ID: 441807 [Multi-domain]  Cd Length: 239  Bit Score: 58.76  E-value: 1.49e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 437 SIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGS 516
Cdd:COG2205  87 ELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITI-SARREGDGV 165
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 517 LVVIDDDGPDM----------RYMTQMHSLTPFGAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISPrssdaa 586
Cdd:COG2205 166 RISVSDNGPGIpeeelerifeRFYRGDNSRGEGGTGL----------------GLAIVKRIVEAHGGTIWVESE------ 223
                       170
                ....*....|....*..
gi 18408874 587 lGAGGTRVELWLPAFPA 603
Cdd:COG2205 224 -PGGGTTFTVTLPLAES 239
BaeS COG0642
Signal transduction histidine kinase [Signal transduction mechanisms];
437-600 2.64e-09

Signal transduction histidine kinase [Signal transduction mechanisms];


Pssm-ID: 440407 [Multi-domain]  Cd Length: 328  Bit Score: 59.15  E-value: 2.64e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 437 SIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGS 516
Cdd:COG0642 178 EPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTV-SVRREGDRV 256
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 517 LVVIDDDGPDM----------RYMTQMHSLTPFGAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISprssdaA 586
Cdd:COG0642 257 RISVEDTGPGIppedlerifePFFRTDPSRRGGGTGL----------------GLAIVKRIVELHGGTIEVES------E 314
                       170
                ....*....|....
gi 18408874 587 LGaGGTRVELWLPA 600
Cdd:COG0642 315 PG-KGTTFTVTLPL 327
WalK COG5002
Sensor histidine kinase WalK [Signal transduction mechanisms];
439-603 7.65e-07

Sensor histidine kinase WalK [Signal transduction mechanisms];


Pssm-ID: 444026 [Multi-domain]  Cd Length: 390  Bit Score: 51.86  E-value: 7.65e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 439 RPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGSLV 518
Cdd:COG5002 238 EPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITV-SLREEDDQVRI 316
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 519 VIDDDGP-----DMRYMTQmhsltPF------------GAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISpr 581
Cdd:COG5002 317 SVRDTGIgipeeDLPRIFE-----RFyrvdksrsretgGTGL----------------GLAIVKHIVEAHGGRIWVES-- 373
                       170       180
                ....*....|....*....|..
gi 18408874 582 ssdaALGaGGTRVELWLPAFPA 603
Cdd:COG5002 374 ----EPG-KGTTFTITLPLARE 390
HATPase_c pfam02518
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
480-599 3.52e-06

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.


Pssm-ID: 460579 [Multi-domain]  Cd Length: 109  Bit Score: 46.21  E-value: 3.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874   480 EPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGSLVVIdDDGPDMRYMTQMHSLTPFGaellsenMVEDNMTWNFVA 559
Cdd:pfam02518   3 ELRLRQVLSNLLDNALKHAAKAGEITV-TLSEGGELTLTVE-DNGIGIPPEDLPRIFEPFS-------TADKRGGGGTGL 73
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 18408874   560 GLTVAREILESYGCVIRVISPRSsdaalgaGGTRVELWLP 599
Cdd:pfam02518  74 GLSIVRKLVELLGGTITVESEPG-------GGTTVTLTLP 106
HATPase_c smart00387
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
480-599 1.54e-05

Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.


Pssm-ID: 214643 [Multi-domain]  Cd Length: 111  Bit Score: 44.18  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874    480 EPALRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVVIdDDGPDMRYMTQMHSLTPFGAELLSENMVEdnmtwNFVA 559
Cdd:smart00387   3 PDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVE-DNGPGIPPEDLEKIFEPFFRTDKRSRKIG-----GTGL 76
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 18408874    560 GLTVAREILESYGCVIRVISPRSsdaalgaGGTRVELWLP 599
Cdd:smart00387  77 GLSIVKKLVELHGGEISVESEPG-------GGTTFTITLP 109
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
439-605 2.05e-05

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 47.26  E-value: 2.05e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 439 RPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEIlSTRAPAGGSLV 518
Cdd:COG5000 274 EPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEV-STRREDGRVRI 352
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874 519 VIDDDGP----DMR------YMTqmhslT-PFGAELlsenmvednmtwnfvaGLTVAREILESYGCVIRVISprssdaAL 587
Cdd:COG5000 353 EVSDNGPgipeEVLerifepFFT-----TkPKGTGL----------------GLAIVKKIVEEHGGTIELES------RP 405
                       170
                ....*....|....*...
gi 18408874 588 GaGGTRVELWLPAFPAAV 605
Cdd:COG5000 406 G-GGTTFTIRLPLAEEAE 422
PRK11100 PRK11100
sensory histidine kinase CreC; Provisional
428-525 5.35e-05

sensory histidine kinase CreC; Provisional


Pssm-ID: 236846 [Multi-domain]  Cd Length: 475  Bit Score: 45.99  E-value: 5.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18408874  428 LALAPL-QMHSIR---PCDISNVLLDMVETVRPLAltQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGK 503
Cdd:PRK11100 312 LELARLeQRQELEvlePVALAALLEELVEAREAQA--AAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGT 389
                         90       100
                 ....*....|....*....|..
gi 18408874  504 VEiLSTRAPAGGSLVVIDDDGP 525
Cdd:PRK11100 390 IT-LSAEVDGEQVALSVEDQGP 410
HATPase_BaeS-like cd16946
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ...
483-525 5.45e-04

Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.


Pssm-ID: 340422 [Multi-domain]  Cd Length: 109  Bit Score: 39.75  E-value: 5.45e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 18408874 483 LRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVViDDDGP 525
Cdd:cd16946   5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDV-EDSAP 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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