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Conserved domains on  [gi|18400231|ref|NP_564477|]
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transmembrane 50A-like protein [Arabidopsis thaliana]

Protein Classification

UPF0220 family protein( domain architecture ID 4022)

UPF0220 family protein similar to Homo sapiens transmembrane protein 50A/B and Saccharomyces cerevisiae vacuolar protein sorting-associated protein 68 (VPS68)

Gene Ontology:  GO:0032511
TCDB:  9.B.199

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UPF0220 super family cl05018
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 14-134 2.29e-19

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


The actual alignment was detected with superfamily member pfam05255:

Pssm-ID: 428395  Cd Length: 160  Bit Score: 78.40  E-value: 2.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400231    14 FSGAVFGTGWWFWVDAVVCSS------IQVPFVHYLPGIFASLGALMFNCVRK-----EDIDYSPyDEGEWRLKLWLFIA 82
Cdd:pfam05255  22 LAGALFAIGWWLFIDAAVYSKsangsdVHVTFVDWIPGICSTLGMLIVNSIEKsqlrgDSLGYTG-SGVAWKARVVLFLG 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 18400231    83 YVVAFVSLAASVGLLIQDSVVK---TGPSTWTGVAGVFQCVFVLISGLMYWTSHS 134
Cdd:pfam05255 101 FALLAGGLAGSVWVLILKYVVPgytTYPTLGMGVANVLQNALIFLSSLVLWFGQN 155
 
Name Accession Description Interval E-value
UPF0220 pfam05255
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 14-134 2.29e-19

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


Pssm-ID: 428395  Cd Length: 160  Bit Score: 78.40  E-value: 2.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400231    14 FSGAVFGTGWWFWVDAVVCSS------IQVPFVHYLPGIFASLGALMFNCVRK-----EDIDYSPyDEGEWRLKLWLFIA 82
Cdd:pfam05255  22 LAGALFAIGWWLFIDAAVYSKsangsdVHVTFVDWIPGICSTLGMLIVNSIEKsqlrgDSLGYTG-SGVAWKARVVLFLG 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 18400231    83 YVVAFVSLAASVGLLIQDSVVK---TGPSTWTGVAGVFQCVFVLISGLMYWTSHS 134
Cdd:pfam05255 101 FALLAGGLAGSVWVLILKYVVPgytTYPTLGMGVANVLQNALIFLSSLVLWFGQN 155
 
Name Accession Description Interval E-value
UPF0220 pfam05255
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 14-134 2.29e-19

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


Pssm-ID: 428395  Cd Length: 160  Bit Score: 78.40  E-value: 2.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18400231    14 FSGAVFGTGWWFWVDAVVCSS------IQVPFVHYLPGIFASLGALMFNCVRK-----EDIDYSPyDEGEWRLKLWLFIA 82
Cdd:pfam05255  22 LAGALFAIGWWLFIDAAVYSKsangsdVHVTFVDWIPGICSTLGMLIVNSIEKsqlrgDSLGYTG-SGVAWKARVVLFLG 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 18400231    83 YVVAFVSLAASVGLLIQDSVVK---TGPSTWTGVAGVFQCVFVLISGLMYWTSHS 134
Cdd:pfam05255 101 FALLAGGLAGSVWVLILKYVVPgytTYPTLGMGVANVLQNALIFLSSLVLWFGQN 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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