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Conserved domains on  [gi|18394565|ref|NP_564045|]
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Protein phosphatase 2C family protein [Arabidopsis thaliana]

Protein Classification

PP2C family serine/threonine-protein phosphatase( domain architecture ID 10065450)

PP2C family protein-serine/threonine phosphatase catalyzes the dephosphorylation of phosphoserine and phosphothreonine residues of specific protein substrates

CATH:  3.60.40.10
EC:  3.1.3.16
Gene Ontology:  GO:0004722|GO:0006470|GO:0046872
PubMed:  9192069|8819174
SCOP:  3000909

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PP2Cc cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
77-348 2.35e-74

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


:

Pssm-ID: 238083 [Multi-domain]  Cd Length: 254  Bit Score: 230.29  E-value: 2.35e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  77 VAEDKGARHTMEDVWVVLPDAsldfpGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVAKKAILEGF 156
Cdd:cd00143   5 VSDKGGDRKTNEDAVVIKPNL-----NNEDGGLFGVFDGHGGHAAGEFASKLLVEELLEELEETLTLSEEDIEEALRKAF 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 157 RKTDELLLQKSVS--GGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQ 234
Cdd:cd00143  80 LRADEEILEEAQDepDDARSGTTAVVALIRGNKLYVANVGDSRAVLCRNG---------------EAVQLTKDHKPVNEE 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 235 ERSRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKkFGVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLL 314
Cdd:cd00143 145 ERERIEKAGGRVS-NGRVPGVLAVTRALGDFDLK-PGVSAEPDVTVVKLTEDDDFLILASDGLWDVLSNQEAVDIVRSEL 222
                       250       260       270
                ....*....|....*....|....*....|....
gi 18394565 315 KEGlHVSTVSRRLVKEAvKERRCKDNCTAIVIVF 348
Cdd:cd00143 223 AKE-DLQEAAQELVDLA-LRRGSHDNITVVVVRL 254
 
Name Accession Description Interval E-value
PP2Cc cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
77-348 2.35e-74

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 238083 [Multi-domain]  Cd Length: 254  Bit Score: 230.29  E-value: 2.35e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  77 VAEDKGARHTMEDVWVVLPDAsldfpGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVAKKAILEGF 156
Cdd:cd00143   5 VSDKGGDRKTNEDAVVIKPNL-----NNEDGGLFGVFDGHGGHAAGEFASKLLVEELLEELEETLTLSEEDIEEALRKAF 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 157 RKTDELLLQKSVS--GGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQ 234
Cdd:cd00143  80 LRADEEILEEAQDepDDARSGTTAVVALIRGNKLYVANVGDSRAVLCRNG---------------EAVQLTKDHKPVNEE 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 235 ERSRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKkFGVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLL 314
Cdd:cd00143 145 ERERIEKAGGRVS-NGRVPGVLAVTRALGDFDLK-PGVSAEPDVTVVKLTEDDDFLILASDGLWDVLSNQEAVDIVRSEL 222
                       250       260       270
                ....*....|....*....|....*....|....
gi 18394565 315 KEGlHVSTVSRRLVKEAvKERRCKDNCTAIVIVF 348
Cdd:cd00143 223 AKE-DLQEAAQELVDLA-LRRGSHDNITVVVVRL 254
PP2Cc smart00332
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
77-346 6.81e-67

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 214625 [Multi-domain]  Cd Length: 252  Bit Score: 211.08  E-value: 6.81e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565     77 VAEDKGARHTMEDVWVVLPDasLDFPGTLrcahFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVaKKAILEGF 156
Cdd:smart00332  13 LSSMQGVRKPMEDAHVITPD--LSDSGGF----FGVFDGHGGSEAAKFLSKNLPEILAEELIKEKDELEDV-EEALRKAF 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    157 RKTDELLLQKSVSGGwqdGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQER 236
Cdd:smart00332  86 LSTDEEILEELEALS---GSTAVVALISGNKLYVANVGDSRAVLCRNG---------------KAVQLTEDHKPSNEDER 147
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    237 SRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKKFgVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLLKE 316
Cdd:smart00332 148 ARIEAAGGFVI-NGRVNGVLALSRAIGDFFLKPY-VSAEPDVTVVELTEKDDFLILASDGLWDVLSNQEVVDIVRKHLSK 225
                          250       260       270
                   ....*....|....*....|....*....|
gi 18394565    317 glHVSTVSRRLVKEAVkERRCKDNCTAIVI 346
Cdd:smart00332 226 --DPKEAAKRLIDLAL-ARGSKDNITVVVV 252
PP2C pfam00481
Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine ...
82-340 6.06e-58

Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.


Pssm-ID: 395385  Cd Length: 252  Bit Score: 187.93  E-value: 6.06e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    82 GARHTMEDVwVVLPDASLDFPGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAglpRELLDVKVAKKAILEGFRKTDE 161
Cdd:pfam00481  10 GWRKSMEDA-HIDLPNLNSSSGKDSWSFFAVFDGHGGSEAAKYCGKHLHTILALR---RSFLEGEKLEDALRKSFLEDTD 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   162 LLLQKSVSGGWQDGATAVCVWILDQKVFVANIGDAKAVLARSsttnelgnhteaGNPLKAivLTREHKAIYPQERSRIQK 241
Cdd:pfam00481  86 EVLRSAEKEDLDSGCTAVVALISGNKLYVANVGDSRAVLCRN------------GNAIKR--LTKDHKPSDEDERRRIRA 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   242 SGGVISSNGRLQGRLEVSRAFGDRHFKKF--GVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLLKEGLH 319
Cdd:pfam00481 152 AGGFVSRNGRVNGVLAVSRAFGDFELKPGeqAVSAEPDITSHTITEDDEFLILACDGLWDVLSDQEVVDLVRSELSDGGS 231
                         250       260
                  ....*....|....*....|.
gi 18394565   320 VSTVSRRLVKEAvKERRCKDN 340
Cdd:pfam00481 232 PMEAAEELRDEA-IAYGSEDN 251
PLN03145 PLN03145
Protein phosphatase 2c; Provisional
80-349 6.09e-46

Protein phosphatase 2c; Provisional


Pssm-ID: 215603 [Multi-domain]  Cd Length: 365  Bit Score: 160.46  E-value: 6.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   80 DKGARHTMEDVWVVLPDASLDFpGTLRC-----AHFAIYDGHGGRLAAEFAKKHL-HLNVLSAGLPRELldvkvaKKAIL 153
Cdd:PLN03145  72 DIGSRSSMEDVYICVDNFMSDF-GLKNSedgpsAFYGVFDGHGGKHAADFACYHLpRFIVEDEDFPREI------EKVVS 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  154 EGFRKTDELLLQK-SVSGGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIY 232
Cdd:PLN03145 145 SAFLQTDTAFAEAcSLDASLASGTTALAALVVGRSLVVANAGDCRAVLCRRG---------------KAIEMSRDHKPMC 209
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  233 PQERSRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKKFG------VSATPDIHAFELTERENFMILGCDGLWEVFGPSDA 306
Cdd:PLN03145 210 SKERKRIEASGGYVY-DGYLNGQLNVARALGDWHMEGMKgsdggpLSAEPELMTTQLTEEDEFLIIGCDGIWDVFRSQNA 288
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 18394565  307 VGFVQKLLKEGLHVSTVSRRLVKEAVKeRRCKDNCTAIVIVFK 349
Cdd:PLN03145 289 VDFARRRLQEHNDPVMCSKELVDEALK-RKSGDNLAVVVVCFQ 330
PTC1 COG0631
Serine/threonine protein phosphatase PrpC [Signal transduction mechanisms];
80-346 3.13e-10

Serine/threonine protein phosphatase PrpC [Signal transduction mechanisms];


Pssm-ID: 440396 [Multi-domain]  Cd Length: 247  Bit Score: 59.84  E-value: 3.13e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  80 DKGA-RHTMEDVWVVLPDASLDFpgtlrcahFAIYDGHGGRLAAEFAKKHLhLNVLSAGLPRELL-DVKVAKKAILEGFR 157
Cdd:COG0631   8 DVGRvRENNEDAFLVALDPGGGL--------FVVADGMGGHAAGEVASRLA-VETLAELFQEALApDPEDLEEALREAIR 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 158 KTDELLLQKSVS-GGWQD-GATAVCVWILDQKVFVANIGDAKAVLARSS-----TTnelgNHTEAGNPLKAIVLTREHKA 230
Cdd:COG0631  79 AANRAILELAQEdPELAGmGTTLVAALIAGGRLYIAHVGDSRAYLLRDGeleqlTR----DHSLVQELVDAGRITPEEAR 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 231 IYPQeRSRIqksggvissngrlqgrlevSRAFGDRHfkkfgvSATPDIHAFELTERENFMIlgC-DGLWEVFgpSDAVgf 309
Cdd:COG0631 155 THPQ-RNVL-------------------TRALGTDD------DVEPDISPLELEPGDRLLL--CsDGLTDMV--SDEE-- 202
                       250       260       270
                ....*....|....*....|....*....|....*..
gi 18394565 310 VQKLLKEGLHVSTVSRRLVKEAvKERRCKDNCTAIVI 346
Cdd:COG0631 203 IAEILASAGDPQEAAEALIELA-LEAGGPDNITVVLV 238
 
Name Accession Description Interval E-value
PP2Cc cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
77-348 2.35e-74

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 238083 [Multi-domain]  Cd Length: 254  Bit Score: 230.29  E-value: 2.35e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  77 VAEDKGARHTMEDVWVVLPDAsldfpGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVAKKAILEGF 156
Cdd:cd00143   5 VSDKGGDRKTNEDAVVIKPNL-----NNEDGGLFGVFDGHGGHAAGEFASKLLVEELLEELEETLTLSEEDIEEALRKAF 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 157 RKTDELLLQKSVS--GGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQ 234
Cdd:cd00143  80 LRADEEILEEAQDepDDARSGTTAVVALIRGNKLYVANVGDSRAVLCRNG---------------EAVQLTKDHKPVNEE 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 235 ERSRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKkFGVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLL 314
Cdd:cd00143 145 ERERIEKAGGRVS-NGRVPGVLAVTRALGDFDLK-PGVSAEPDVTVVKLTEDDDFLILASDGLWDVLSNQEAVDIVRSEL 222
                       250       260       270
                ....*....|....*....|....*....|....
gi 18394565 315 KEGlHVSTVSRRLVKEAvKERRCKDNCTAIVIVF 348
Cdd:cd00143 223 AKE-DLQEAAQELVDLA-LRRGSHDNITVVVVRL 254
PP2Cc smart00332
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
77-346 6.81e-67

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 214625 [Multi-domain]  Cd Length: 252  Bit Score: 211.08  E-value: 6.81e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565     77 VAEDKGARHTMEDVWVVLPDasLDFPGTLrcahFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVaKKAILEGF 156
Cdd:smart00332  13 LSSMQGVRKPMEDAHVITPD--LSDSGGF----FGVFDGHGGSEAAKFLSKNLPEILAEELIKEKDELEDV-EEALRKAF 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    157 RKTDELLLQKSVSGGwqdGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQER 236
Cdd:smart00332  86 LSTDEEILEELEALS---GSTAVVALISGNKLYVANVGDSRAVLCRNG---------------KAVQLTEDHKPSNEDER 147
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    237 SRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKKFgVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLLKE 316
Cdd:smart00332 148 ARIEAAGGFVI-NGRVNGVLALSRAIGDFFLKPY-VSAEPDVTVVELTEKDDFLILASDGLWDVLSNQEVVDIVRKHLSK 225
                          250       260       270
                   ....*....|....*....|....*....|
gi 18394565    317 glHVSTVSRRLVKEAVkERRCKDNCTAIVI 346
Cdd:smart00332 226 --DPKEAAKRLIDLAL-ARGSKDNITVVVV 252
PP2C pfam00481
Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine ...
82-340 6.06e-58

Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.


Pssm-ID: 395385  Cd Length: 252  Bit Score: 187.93  E-value: 6.06e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565    82 GARHTMEDVwVVLPDASLDFPGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAglpRELLDVKVAKKAILEGFRKTDE 161
Cdd:pfam00481  10 GWRKSMEDA-HIDLPNLNSSSGKDSWSFFAVFDGHGGSEAAKYCGKHLHTILALR---RSFLEGEKLEDALRKSFLEDTD 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   162 LLLQKSVSGGWQDGATAVCVWILDQKVFVANIGDAKAVLARSsttnelgnhteaGNPLKAivLTREHKAIYPQERSRIQK 241
Cdd:pfam00481  86 EVLRSAEKEDLDSGCTAVVALISGNKLYVANVGDSRAVLCRN------------GNAIKR--LTKDHKPSDEDERRRIRA 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   242 SGGVISSNGRLQGRLEVSRAFGDRHFKKF--GVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLLKEGLH 319
Cdd:pfam00481 152 AGGFVSRNGRVNGVLAVSRAFGDFELKPGeqAVSAEPDITSHTITEDDEFLILACDGLWDVLSDQEVVDLVRSELSDGGS 231
                         250       260
                  ....*....|....*....|.
gi 18394565   320 VSTVSRRLVKEAvKERRCKDN 340
Cdd:pfam00481 232 PMEAAEELRDEA-IAYGSEDN 251
PLN03145 PLN03145
Protein phosphatase 2c; Provisional
80-349 6.09e-46

Protein phosphatase 2c; Provisional


Pssm-ID: 215603 [Multi-domain]  Cd Length: 365  Bit Score: 160.46  E-value: 6.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   80 DKGARHTMEDVWVVLPDASLDFpGTLRC-----AHFAIYDGHGGRLAAEFAKKHL-HLNVLSAGLPRELldvkvaKKAIL 153
Cdd:PLN03145  72 DIGSRSSMEDVYICVDNFMSDF-GLKNSedgpsAFYGVFDGHGGKHAADFACYHLpRFIVEDEDFPREI------EKVVS 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  154 EGFRKTDELLLQK-SVSGGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIY 232
Cdd:PLN03145 145 SAFLQTDTAFAEAcSLDASLASGTTALAALVVGRSLVVANAGDCRAVLCRRG---------------KAIEMSRDHKPMC 209
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  233 PQERSRIQKSGGVISsNGRLQGRLEVSRAFGDRHFKKFG------VSATPDIHAFELTERENFMILGCDGLWEVFGPSDA 306
Cdd:PLN03145 210 SKERKRIEASGGYVY-DGYLNGQLNVARALGDWHMEGMKgsdggpLSAEPELMTTQLTEEDEFLIIGCDGIWDVFRSQNA 288
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 18394565  307 VGFVQKLLKEGLHVSTVSRRLVKEAVKeRRCKDNCTAIVIVFK 349
Cdd:PLN03145 289 VDFARRRLQEHNDPVMCSKELVDEALK-RKSGDNLAVVVVCFQ 330
PTZ00224 PTZ00224
protein phosphatase 2C; Provisional
82-349 1.73e-26

protein phosphatase 2C; Provisional


Pssm-ID: 240318 [Multi-domain]  Cd Length: 381  Bit Score: 108.32  E-value: 1.73e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565   82 GARHTMEDVWVVLPDASLDFpgtlrcahFAIYDGHGGRLAAEFAKKHLHLNVlsAGLPRELLDVKVAKKAIlegfrKTDE 161
Cdd:PTZ00224  31 GYRESMEDAHLLYLTDDWGF--------FGVFDGHVNDECSQYLARAWPQAL--EKEPEPMTDERMEELCL-----EIDE 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  162 LLLQKSVSGGwqdGATAVCVWILDQKVFVANIGDAKAVLARSSttnelgnhteagnplKAIVLTREHKAIYPQERSRIQK 241
Cdd:PTZ00224  96 EWMDSGREGG---STGTFCVIMKDVHLQVGNVGDSRVLVCRDG---------------KLVFATEDHKPNNPGERQRIEA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  242 SGGVISSNgRLQGRLEVSRAFGDRHFKKFG--------VSATPDIHAFELtERENFMILGCDGLWE-VFGPSDAVGFVQK 312
Cdd:PTZ00224 158 CGGRVVSN-RVDGDLAVSRAFGDRSFKVKGtgdyleqkVIAVPDVTHLTC-QSNDFIILACDGVFEgNFSNEEVVAFVKE 235
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 18394565  313 LLKEGLHVSTVSRRLVKEAVkERRCKDNCTAIVIVFK 349
Cdd:PTZ00224 236 QLETCDDLAVVAGRVCDEAI-RRGSKDNISCLIVQLK 271
PTC1 COG0631
Serine/threonine protein phosphatase PrpC [Signal transduction mechanisms];
80-346 3.13e-10

Serine/threonine protein phosphatase PrpC [Signal transduction mechanisms];


Pssm-ID: 440396 [Multi-domain]  Cd Length: 247  Bit Score: 59.84  E-value: 3.13e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565  80 DKGA-RHTMEDVWVVLPDASLDFpgtlrcahFAIYDGHGGRLAAEFAKKHLhLNVLSAGLPRELL-DVKVAKKAILEGFR 157
Cdd:COG0631   8 DVGRvRENNEDAFLVALDPGGGL--------FVVADGMGGHAAGEVASRLA-VETLAELFQEALApDPEDLEEALREAIR 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 158 KTDELLLQKSVS-GGWQD-GATAVCVWILDQKVFVANIGDAKAVLARSS-----TTnelgNHTEAGNPLKAIVLTREHKA 230
Cdd:COG0631  79 AANRAILELAQEdPELAGmGTTLVAALIAGGRLYIAHVGDSRAYLLRDGeleqlTR----DHSLVQELVDAGRITPEEAR 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18394565 231 IYPQeRSRIqksggvissngrlqgrlevSRAFGDRHfkkfgvSATPDIHAFELTERENFMIlgC-DGLWEVFgpSDAVgf 309
Cdd:COG0631 155 THPQ-RNVL-------------------TRALGTDD------DVEPDISPLELEPGDRLLL--CsDGLTDMV--SDEE-- 202
                       250       260       270
                ....*....|....*....|....*....|....*..
gi 18394565 310 VQKLLKEGLHVSTVSRRLVKEAvKERRCKDNCTAIVI 346
Cdd:COG0631 203 IAEILASAGDPQEAAEALIELA-LEAGGPDNITVVLV 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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