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Conserved domains on  [gi|18391021|ref|NP_563844|]
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glucose-6-phosphate dehydrogenase 4 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02333 super family cl47074
glucose-6-phosphate 1-dehydrogenase
 14-624 0e+00

glucose-6-phosphate 1-dehydrogenase


The actual alignment was detected with superfamily member PLN02333:

Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 623.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  407 DIRNEKVKVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLI 477
Cdd:PLN02333 373 DIRNEKVKVLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVPFLMKAGKALH 452

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  478 KHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYE 557
Cdd:PLN02333 453 TKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAARYSKEIPDAYE 532

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18391021  558 HLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 624
Cdd:PLN02333 533 RLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
 
Name Accession Description Interval E-value
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 14-624 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 623.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  407 DIRNEKVKVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLI 477
Cdd:PLN02333 373 DIRNEKVKVLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVPFLMKAGKALH 452

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  478 KHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYE 557
Cdd:PLN02333 453 TKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAARYSKEIPDAYE 532

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18391021  558 HLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 624
Cdd:PLN02333 533 RLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 152-622 1.05e-160

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 469.49  E-value: 1.05e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTL--TCRVDHQEncggKMDAFQS 229
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIikFETDEIDE----QWDEFAQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   230 RTYYINGGYNNRDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:TIGR00871  77 RLSYVSGDVDDDESYDSLAELLEQLDKTygTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDLASA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:TIGR00871 157 QELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFG-VEgrgGYYDKSGALRDM 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   384 VHSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRD--VILGQYKSSS---------RDKNGVILNGVDPTYC 452
Cdd:TIGR00871 236 VQNHLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDnnTVRGQYGAGEiggvsvpgyLEEEGVDKDSNTETFA 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   453 AAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigINIDLGTNELILRDEPDEAILVKINNKVPGLG 532
Cdd:TIGR00871 316 ALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN--ERDANPRNALVIRIQPDEGVYLKFNAKKPGLN 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   533 LQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTA-PELYEFGGRGPVAA 611
Cdd:TIGR00871 394 FETRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPsPPNYPAGSWGPKEA 473

                         490
                  ....*....|.
gi 18391021   612 YYLWAKHGVPW 622
Cdd:TIGR00871 474 DELIRKDGRSW 484
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 155-622 3.74e-158

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 463.01  E-value: 3.74e-158
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLT--CRVDHQEncgGKMDAFQSRT 231
Cdd:COG0364  10 CDLVIfGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEefSRKPFDE---EVWERFLERL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 232 YYINGGYNNRDGMSRLAERMKQIEGE-SEANRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQL 309
Cdd:COG0364  87 HYVSGDFTDPEGYERLKELLEELDEErTPGNRVFYLATPPSLFGPICENLGAAGLAtEGGWRRVVIEKPFGHDLASAREL 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 310 TKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESI-----AqteKFSDGYGIIRDIV 384
Cdd:COG0364 167 NDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVgvegrG---GYYDGAGALRDMV 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 385 HSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDV----ILGQYKSssrdknGVIL----------NGVDP- 449
Cdd:COG0364 244 QNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDVaentVRGQYTA------GWIGgepvpgyreePGVAPd 317

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 450 ----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigiNIDLGTNELILRDEPDEAILVKIN 525
Cdd:COG0364 318 stteTFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRET---AEELPPNRLVIRIQPDEGISLRFN 394

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 526 NKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGG 605
Cdd:COG0364 395 AKVPGLGMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGS 474

                       490
                ....*....|....*..
gi 18391021 606 RGPVAAYYLWAKHGVPW 622
Cdd:COG0364 475 WGPEAADALLARDGRSW 491
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
339-622 6.87e-141

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 411.45  E-value: 6.87e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   339 VLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVKV 415
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLG-VEGrggYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   416 LRSIRKIDPRDV----ILGQYKSSSRDKNGVI----LNGVDP-----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVE 482
Cdd:pfam02781  81 LRSLRPITPEDVednvVRGQYGAGWIGGEPVPgyreEEGVPPdsrteTFAALKLFIDNWRWAGVPFYLRTGKRLPERVTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   483 IHVQFRHVPGNLYRENIGinidLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHD 562
Cdd:pfam02781 161 IRIQFKDVPHNLFRDPGT----LPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERIPEAYERLLLD 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   563 VIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHtaPELYEFGGRGPVAAYYLWAKHGVPW 622
Cdd:pfam02781 237 VMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKW 294
 
Name Accession Description Interval E-value
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 14-624 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 623.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  407 DIRNEKVKVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLI 477
Cdd:PLN02333 373 DIRNEKVKVLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVPFLMKAGKALH 452

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  478 KHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYE 557
Cdd:PLN02333 453 TKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAARYSKEIPDAYE 532

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18391021  558 HLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 624
Cdd:PLN02333 533 RLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
PLN02640 PLN02640
glucose-6-phosphate 1-dehydrogenase
 152-624 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215344 [Multi-domain]  Cd Length: 573  Bit Score: 620.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRT 231
Cdd:PLN02640  87 STLSITVVGASGDLAKKKIFPALFALFYEDWLPENFTVFGYARTKLTDEELRDMISSTLTCRIDQRENCGDKMDQFLKRC 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  232 YYINGGYNNRDGMSRLAERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTK 311
Cdd:PLN02640 167 FYHSGQYDSEEDFAELNKKLKEKEAGKLSNRLFYLSIPPNIFVDVVRCASLRASSENGWTRVIVEKPFGRDSESSGELTR 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  312 SLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHIL 389
Cdd:PLN02640 247 CLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRggYFDNYGIIRDIMQNHLL 326

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  390 QTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDN 460
Cdd:PLN02640 327 QILALFAMETPVSLDAEDIRNEKVKVLRSMKPLQLEDVIVGQYKGHSKggksypaytDDPTVPKHSLTPTFAAAALFINN 406

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  461 ARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASEL 540
Cdd:PLN02640 407 ARWDGVPFLMKAGKALHTRRAEIRVQFRHVPGNLYKRNFGTDLDKATNELVLRVQPDEAIYLKINNKVPGLGMRLDRSDL 486

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  541 NLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGV 620
Cdd:PLN02640 487 NLLYRARYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPELYPYGSRGPVGAHYLAAKYNV 566


                 ....
gi 18391021  621 PWAD 624
Cdd:PLN02640 567 RWGD 570
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 130-619 2.31e-164

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 480.79  E-value: 2.31e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  130 NVGDLPPVSKQLSDDLSDVRRRASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDlRSIIAST 209
Cdd:PTZ00309  31 KPDNGTESCDRIPCKVKDEDKSRALTIIVLGASGDLAKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVE-RWKKETL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  210 LTCRVDHQENCGgKMDAFQSRTYYINGGYNNRDGMSRLAERMKQIEG-----ESEANRIFYLSVPQEALVDVACTIGDNA 284
Cdd:PTZ00309 110 ARFFKRLDDREC-HLEQFLKHISYISGSYDEDEDFKRLNKLIERMEEafqgpEKGGNRLFYLALPPSVFASVCEGIHRGC 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  285 QAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIIS 364
Cdd:PTZ00309 189 MSKNGWVRVIVEKPFGRDLESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFK 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  365 ESIAqTE---KFSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDVILGQYKSSS----- 436
Cdd:PTZ00309 269 EDIG-TEgrgGYFDSYGIIRDVMQNHLLQILALLAMEKPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASAdgsip 347

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  437 --RDKNGVILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYrenigINIDLGTNELILRD 514
Cdd:PTZ00309 348 gyLEDEGVPKDSTTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKGVDEFRP-----SGDDTQRNELVIRA 422

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  515 EPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKH 594
Cdd:PTZ00309 423 QPSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYNVRLPDAYERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQIDRG 502

                        490       500
                 ....*....|....*....|....*
gi 18391021  595 HTAPELYEFGGRGPVAAYYLWAKHG 619
Cdd:PTZ00309 503 EVKPEPYPFGSRGPKEADELIKKNG 527
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 152-622 1.05e-160

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 469.49  E-value: 1.05e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTL--TCRVDHQEncggKMDAFQS 229
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIikFETDEIDE----QWDEFAQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   230 RTYYINGGYNNRDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:TIGR00871  77 RLSYVSGDVDDDESYDSLAELLEQLDKTygTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDLASA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:TIGR00871 157 QELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFG-VEgrgGYYDKSGALRDM 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   384 VHSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRD--VILGQYKSSS---------RDKNGVILNGVDPTYC 452
Cdd:TIGR00871 236 VQNHLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDnnTVRGQYGAGEiggvsvpgyLEEEGVDKDSNTETFA 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   453 AAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigINIDLGTNELILRDEPDEAILVKINNKVPGLG 532
Cdd:TIGR00871 316 ALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN--ERDANPRNALVIRIQPDEGVYLKFNAKKPGLN 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   533 LQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTA-PELYEFGGRGPVAA 611
Cdd:TIGR00871 394 FETRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPsPPNYPAGSWGPKEA 473

                         490
                  ....*....|.
gi 18391021   612 YYLWAKHGVPW 622
Cdd:TIGR00871 474 DELIRKDGRSW 484
PRK05722 PRK05722
glucose-6-phosphate 1-dehydrogenase; Validated
 155-622 6.55e-159

glucose-6-phosphate 1-dehydrogenase; Validated


Pssm-ID: 235579 [Multi-domain]  Cd Length: 495  Bit Score: 464.99  E-value: 6.55e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  155 CIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVdHQENCGGKMDAFQSRTYYI 234
Cdd:PRK05722  11 DLVIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSDEDFREVVREALKEFA-RTPFDEEVWERFLSRLYYV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  235 NGGYNNRDGMSRLAERMKQIEGESEA--NRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQLTK 311
Cdd:PRK05722  90 SGDVTDPESYERLKELLEELDEERGTggNRVFYLATPPSLFGTICENLAAAGLNeGGGWRRVVIEKPFGHDLASARELND 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  312 SLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHI 388
Cdd:PRK05722 170 QVGEVFKEEQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVG-VEGrggYYDKSGALRDMVQNHL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  389 LQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDV----ILGQYKSSS---------RDKNGVILNGVDPTYCAAA 455
Cdd:PRK05722 249 LQLLALVAMEPPASLDADSIRDEKVKVLRALRPITPEDVkentVRGQYTAGWiggkpvpgyREEEGVNPDSTTETFVALK 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  456 LYIDNARWDGVPFLVRVGTGLiKHRV-EIHVQFRHVPGNLYRENIGiniDLGTNELILRDEPDEAILVKINNKVPGLGLQ 534
Cdd:PRK05722 329 LEIDNWRWAGVPFYLRTGKRL-PKKVtEIVIVFKPPPHNLFEESAE---ELGPNKLVIRIQPDEGISLRFNAKVPGEGME 404

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  535 LDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYL 614
Cdd:PRK05722 405 LRPVKLDFSYSEAFGEASPEAYERLLLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAGTWGPEAADAL 484


                 ....*...
gi 18391021  615 WAKHGVPW 622
Cdd:PRK05722 485 LARDGRSW 492
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 155-622 3.74e-158

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 463.01  E-value: 3.74e-158
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLT--CRVDHQEncgGKMDAFQSRT 231
Cdd:COG0364  10 CDLVIfGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEefSRKPFDE---EVWERFLERL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 232 YYINGGYNNRDGMSRLAERMKQIEGE-SEANRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQL 309
Cdd:COG0364  87 HYVSGDFTDPEGYERLKELLEELDEErTPGNRVFYLATPPSLFGPICENLGAAGLAtEGGWRRVVIEKPFGHDLASAREL 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 310 TKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESI-----AqteKFSDGYGIIRDIV 384
Cdd:COG0364 167 NDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVgvegrG---GYYDGAGALRDMV 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 385 HSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDV----ILGQYKSssrdknGVIL----------NGVDP- 449
Cdd:COG0364 244 QNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDVaentVRGQYTA------GWIGgepvpgyreePGVAPd 317

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 450 ----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigiNIDLGTNELILRDEPDEAILVKIN 525
Cdd:COG0364 318 stteTFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRET---AEELPPNRLVIRIQPDEGISLRFN 394

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021 526 NKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGG 605
Cdd:COG0364 395 AKVPGLGMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGS 474

                       490
                ....*....|....*..
gi 18391021 606 RGPVAAYYLWAKHGVPW 622
Cdd:COG0364 475 WGPEAADALLARDGRSW 491
PLN02539 PLN02539
glucose-6-phosphate 1-dehydrogenase
 154-619 1.10e-146

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 178154 [Multi-domain]  Cd Length: 491  Bit Score: 433.77  E-value: 1.10e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  154 LCIAVVGATGELARGKIFPALFALYYSGYLPED-VAIFGVSRKNLTDEDLRSIIASTLtcrVDHQENCGGKMDAFQSRTY 232
Cdd:PLN02539  18 LSIIVLGASGDLAKKKTFPALFNLYRQGFLPPDeVHIFGYARSKITDEELRDRIRGYL---KDEKNAPAEAVSKFLQLIK 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  233 YINGGYNNRDGMSRLAERMKQIE-----GESEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:PLN02539  95 YVSGAYDSEEGFRRLDKEISEHEisknsAEGSSRRLFYLALPPSVYPPVCKMIKKCCMNKSGlWTRIVVEKPFGKDLESA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:PLN02539 175 EELSSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRFFLPLWNRDNIANVQIVFREDFG-TEgrgGYFDEYGIIRDI 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  384 VHSHILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDVILGQYKsSSRDKNGVILNGVDPTYCAAALYIDNARW 463
Cdd:PLN02539 254 IQNHLLQVLCLVAMEKPVSLKPEHIRDEKVKVLQSVEPIKDEEVVLGQYE-GYRDDPTVPDDSNTPTFASVVLRINNERW 332

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  464 DGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENiginiDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLL 543
Cdd:PLN02539 333 EGVPFILKAGKALDSRKAEIRVQFKDVPGDIFKCQ-----KQGRNEFVIRLQPSEAMYMKLTVKQPGLEMSTVQSELDLS 407

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18391021  544 YKDRYK-TEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHG 619
Cdd:PLN02539 408 YGQRYQdVVIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRIDAGKVKPIPYKQGSRGPAEADELLEKAG 484
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
339-622 6.87e-141

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 411.45  E-value: 6.87e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   339 VLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVKV 415
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLG-VEGrggYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   416 LRSIRKIDPRDV----ILGQYKSSSRDKNGVI----LNGVDP-----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVE 482
Cdd:pfam02781  81 LRSLRPITPEDVednvVRGQYGAGWIGGEPVPgyreEEGVPPdsrteTFAALKLFIDNWRWAGVPFYLRTGKRLPERVTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   483 IHVQFRHVPGNLYRENIGinidLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHD 562
Cdd:pfam02781 161 IRIQFKDVPHNLFRDPGT----LPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERIPEAYERLLLD 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   563 VIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHtaPELYEFGGRGPVAAYYLWAKHGVPW 622
Cdd:pfam02781 237 VMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKW 294
PRK12853 PRK12853
glucose-6-phosphate dehydrogenase;
155-622 2.39e-136

glucose-6-phosphate dehydrogenase;


Pssm-ID: 237233 [Multi-domain]  Cd Length: 482  Bit Score: 406.98  E-value: 2.39e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLtcrvdhQENCGGKMDA-----FQ 228
Cdd:PRK12853   9 CTLVIfGATGDLARRKLLPALYRLARAGLLPEDLRIIGVGRDDWSDEQWRARVRESL------RAFGADGFDDavwdrLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  229 SRTYYINGGYNNRDGMSRLAERMkqiegESEANRIFYLSVPQEALVDVaCTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQ 308
Cdd:PRK12853  83 ARLSYVQGDVTDPADYARLAEAL-----GPGGNPVFYLAVPPSLFAPV-VENLGAAGLLPEGRRVVLEKPFGHDLASARA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  309 LTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIA--QTEKFSDGYGIIRDIVHS 386
Cdd:PRK12853 157 LNATLAKVFDEDQIYRIDHFLGKETVQNLLALRFANALLEPLWNRNHIDHVQITVAETLGveGRGGFYDATGALRDMVQN 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  387 HILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDVIL--GQYKSSSRDKNGVI----LNGVDP-----TYCAAA 455
Cdd:PRK12853 237 HLLQLLALVAMEPPASFDADAVRDEKAKVLRAIRPLDPDDVHTvrGQYTAGTVGGEPVPgyreEPGVDPdsrteTFVALK 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  456 LYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYREnigiNIDLGTNELILRDEPDEAILVKINNKVPGLGLQL 535
Cdd:PRK12853 317 LEIDNWRWAGVPFYLRTGKRLAERRTEIVITFKPVPHALFRG----TGVEPPNRLVIRLQPDEGISLELNVKRPGPGMRL 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  536 DASELNLLYKDRykTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLW 615
Cdd:PRK12853 393 RPVELDADYADD--ERPLEAYERLLLDVLRGDPTLFVRADEVEAAWRIVDPVLDAWAADPVPPHEYPAGSWGPAAADALL 470


                 ....*..
gi 18391021  616 AKHGVPW 622
Cdd:PRK12853 471 ARDGRGW 477
PRK12854 PRK12854
glucose-6-phosphate 1-dehydrogenase; Provisional
 156-619 7.05e-112

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 237234 [Multi-domain]  Cd Length: 484  Bit Score: 343.94  E-value: 7.05e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  156 IAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIastltcRVDHQENCGGKMD-----AFQSR 230
Cdd:PRK12854  14 FVLFGATGDLAKRKLLPGLFHLARAGLLPPDWRIVGTGRGDVSAEAFREHA------RDALDEFGARKLDdgewaRFAKR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  231 TYYINGGYNNrDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRgwTRIIVEKPFGFNSHSSHQ 308
Cdd:PRK12854  88 LRYVPGGFLS-AGPGALAAAVAAARAElgGDARLVHYLAVPPSAFLDVTRALGEAGLAEG--SRVVMEKPFGTDLASAEA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  309 LTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISES--IAQTEKFSDGYGIIRDIVHS 386
Cdd:PRK12854 165 LNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNREFIDHVQIDVPETlgVDTRAAFYDATGAYRDMVVT 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  387 HILQTIALLAMEPPISLDGEDIRNEKVKVLRSIRKIDPRDVILGQYkSSSRDKNGVILNGVDPTYCAAALYIDNARWDGV 466
Cdd:PRK12854 245 HLFQVLAFVAMEPPTALEPDAISEEKNKVFRSMRPLDPAEVVRGQY-SGYRDEPGVAPDSTTETFVALKVWIDNWRWAGV 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021  467 PFLVRVGTGLIKHRVEIHVQFRHVPGNLYRenIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKD 546
Cdd:PRK12854 324 PFYLRTGKRMAEGQRIISIAFREPPYSMFP--AGSVGAQGPDHLTFDLADNSKVSLSFYGKRPGPGMRLDKLSLQFSLKD 401

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18391021  547 -RYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEeidkHHTAPELYEFGGRGPVAAYYLWAKHG 619
Cdd:PRK12854 402 tGPKGDVLEAYERLILDALRGDHTLFTTADGIESLWEVSQPLLE----DPPPVKPYAPGSWGPNAIHQLAAPDA 471
G6PD_N pfam00479
Glucose-6-phosphate dehydrogenase, NAD binding domain;
158-336 2.25e-58

Glucose-6-phosphate dehydrogenase, NAD binding domain;


Pssm-ID: 459827 [Multi-domain]  Cd Length: 178  Bit Score: 193.79  E-value: 2.25e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   158 VVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENcggKMDAFQSRTYYINGG 237
Cdd:pfam00479   2 IFGATGDLAKRKLFPALYNLYRDGLLPEGFRIIGVARRDLSDEEFRERVREALKEFKELDEE---KWDRFLERLHYVSGD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18391021   238 YNNRDGMSRLAERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPR-GWTRIIVEKPFGFNSHSSHQLTKSLLSK 316
Cdd:pfam00479  79 FDDPESYEKLKERLEEHEDETRGNRLFYLAVPPSLFGPIAENLGRAGLSEEgGWRRVVIEKPFGHDLESARELNDQLAKV 158

                         170       180
                  ....*....|....*....|
gi 18391021   317 FEEKQIYRIDHMLGRNLIEN 336
Cdd:pfam00479 159 FKEEQIYRIDHYLGKETVQN 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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