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Conserved domains on  [gi|24660611|ref|NP_524657|]
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farinelli [Drosophila melanogaster]

Protein Classification

motile sperm domain-containing protein( domain architecture ID 10457611)

motile sperm domain-containing protein may form filaments, similar to major motile sperm protein (MSP) and vesicle-associated membrane protein-associated proteins

CATH:  2.60.40.10
SCOP:  4007566

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
8-114 2.57e-27

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


:

Pssm-ID: 459882  Cd Length: 109  Bit Score: 100.13  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611     8 KLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTqRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQ-IKKR 86
Cdd:pfam00635   1 LLTIDPPDLIFFAAPGNKQGTSTLTLKNTSDK-RVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPgDAKK 79
                          90       100
                  ....*....|....*....|....*...
gi 24660611    87 HKFLLLAAEVTGDISDVQEFWKMQNPNE 114
Cdd:pfam00635  80 DKFVIQYAVAPGDEKDAKEAFKRAWKTG 107
 
Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
8-114 2.57e-27

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


Pssm-ID: 459882  Cd Length: 109  Bit Score: 100.13  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611     8 KLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTqRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQ-IKKR 86
Cdd:pfam00635   1 LLTIDPPDLIFFAAPGNKQGTSTLTLKNTSDK-RVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPgDAKK 79
                          90       100
                  ....*....|....*....|....*...
gi 24660611    87 HKFLLLAAEVTGDISDVQEFWKMQNPNE 114
Cdd:pfam00635  80 DKFVIQYAVAPGDEKDAKEAFKRAWKTG 107
SCS2 COG5066
VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and ...
17-160 1.56e-17

VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion];


Pssm-ID: 227398 [Multi-domain]  Cd Length: 242  Bit Score: 78.08  E-value: 1.56e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611  17 IVFEGPFNRSVSRKLVIKNTSkTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQI---KKRHKFLLLA 93
Cdd:COG5066   9 TTFYVPLTNKSKEMFSVQNNS-PEPVGFKVKTTAPKDYCVRPNMGLIEPMSTVEVEVILQGLTEEPApdfKCRDKFLIQS 87
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611  94 AEVTGDIS--DVQEFWKMQNPNETRETKIKC---------ELVPSKEDDFRQAG--GSAVISTDNKDgEVHFDAQEVSEP 160
Cdd:COG5066  88 YRFDWRLSgsDFADHWTSSSKKPIWTRKIRCvyseeeiskNVHECSEDRGAAVLlvEMPTLLNILYL-EVRFFVNQKEVP 166
 
Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
8-114 2.57e-27

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


Pssm-ID: 459882  Cd Length: 109  Bit Score: 100.13  E-value: 2.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611     8 KLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTqRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQ-IKKR 86
Cdd:pfam00635   1 LLTIDPPDLIFFAAPGNKQGTSTLTLKNTSDK-RVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPgDAKK 79
                          90       100
                  ....*....|....*....|....*...
gi 24660611    87 HKFLLLAAEVTGDISDVQEFWKMQNPNE 114
Cdd:pfam00635  80 DKFVIQYAVAPGDEKDAKEAFKRAWKTG 107
SCS2 COG5066
VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and ...
17-160 1.56e-17

VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion];


Pssm-ID: 227398 [Multi-domain]  Cd Length: 242  Bit Score: 78.08  E-value: 1.56e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611  17 IVFEGPFNRSVSRKLVIKNTSkTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQI---KKRHKFLLLA 93
Cdd:COG5066   9 TTFYVPLTNKSKEMFSVQNNS-PEPVGFKVKTTAPKDYCVRPNMGLIEPMSTVEVEVILQGLTEEPApdfKCRDKFLIQS 87
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24660611  94 AEVTGDIS--DVQEFWKMQNPNETRETKIKC---------ELVPSKEDDFRQAG--GSAVISTDNKDgEVHFDAQEVSEP 160
Cdd:COG5066  88 YRFDWRLSgsDFADHWTSSSKKPIWTRKIRCvyseeeiskNVHECSEDRGAAVLlvEMPTLLNILYL-EVRFFVNQKEVP 166
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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