|
Name |
Accession |
Description |
Interval |
E-value |
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
180-929 |
0e+00 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 1314.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQDFRER 259
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGGDNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 QGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMT 339
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGADLFREEWPSLLEELVDTGKITAEQAEEHRHLTIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSAGQ 419
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERPPEEGWEDQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 420 RLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVV 499
Cdd:TIGR02478 241 RKTIVIVAEGAIDRDLNPITSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPETPSPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 500 ISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIegyRLAVMHI 579
Cdd:TIGR02478 321 ISLRGNKIVRKPLVEAVAQTKTVAKAIEEKDFDEAMRLRGREFAENLETFLFLSIPDDDKKLVPSEASRL---RIAIIHV 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 580 GAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLPEGKFKEIAARLKEF 659
Cdd:TIGR02478 398 GAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRSLPGDDLGTIAYYFQQH 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 660 KIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVF 739
Cdd:TIGR02478 478 KIDGLIIIGGFEAFEALYQLDAAREKYPAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIKQSASASKRRVF 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 740 VIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEG 819
Cdd:TIGR02478 558 VVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRAGKLILRNEKASKVYTTDFIARIISEEG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 820 KGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCksPDTATLLGIVSRQYRFSPLVD-L 898
Cdd:TIGR02478 638 KGRFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKANKHADKLSAD--DTSAVVIGIRGSNVLFTPVKQlL 715
|
730 740 750
....*....|....*....|....*....|.
gi 17647809 899 IAETNFDQRIPKKQWWLRLRPLLRILAKHDS 929
Cdd:TIGR02478 716 ANETDFEHRRPKNQWWLQLRPLVRILAGRDS 746
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
178-914 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 1065.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 178 KDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQDFR 257
Cdd:cd00764 2 AGKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGGDYIKQAEWESVSNWLQEGGTIIGSARCKEFR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 258 ERQGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTD 337
Cdd:cd00764 82 EREGRLQAAYNLIQRGITNLCVIGGDGSLTGADLFRSEWPSLLEELVKDGKITEEEVAKYQHLNIVGMVGSIDNDFCGTD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 338 MTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSA 417
Cdd:cd00764 162 MTIGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDGWEDQMCRRLSEHRSR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 418 GQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVP 497
Cdd:cd00764 242 GKRLNIIIVAEGAIDDQLKPITSEDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEATPDTPA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 498 VVISLDGNQAVRVPLMECVERTQAVAKAMAEKRWADAVKLRGRSFERNLETYKML--TRLKPPKENfdadgkgiEGYRLA 575
Cdd:cd00764 322 CVVSLNGNKAVRLPLMECVQLTKDVQKAMDEKRFDEAAALRGKSFDKNWNLYKLLaiELPQPLPEK--------TNLNIA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 576 VMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLPEGKFKEIAAR 655
Cdd:cd00764 394 IVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDLETIAYN 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 656 LKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTK 735
Cdd:cd00764 474 FQKYGIDGLIIVGGFEAYKGLLQLREAREQYEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQSASGTK 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 736 RRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLY 815
Cdd:cd00764 554 RRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHLTEKMKTTIGRGLVLRNEKCNENYTTVFTYELY 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 816 SEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKANIdANGVVNCKSPDTATLLGIVSRQYRFSPl 895
Cdd:cd00764 634 SEEGKGVFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLKENY-AAGNEFANDPDFNCVNGVKKYAVLFEP- 711
|
730
....*....|....*....
gi 17647809 896 VDLIAETNFDQRIPKKQWW 914
Cdd:cd00764 712 VEELKQTTFEHRIPKEQWW 730
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
180-547 |
1.10e-161 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 477.18 E-value: 1.10e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRER 259
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGD--IKELDWESVSDIINRGGTIIGSARCKEFRTE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 QGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSSLldelvknktitteqQEKFNVlhiVGLVGSIDNDFCGTDMT 339
Cdd:cd00363 79 EGRAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSK--------------YQGFNV---IGLPGTIDNDIKGTDYT 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVDWPDRLCSQLAQERSAGQ 419
Cdd:cd00363 142 IGFDTALKTIVEAIDRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEEMVDVIKKRRERGK 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 420 RLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVV 499
Cdd:cd00363 222 RHGIVIVAEGAIDFIPKPITEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGI 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 17647809 500 ISLDGNQAVRVPLMECVERTQAVakamaekrwadAVKLRGRSFERNLE 547
Cdd:cd00363 302 QNLNENQVVRHPLTEAVNMTKRV-----------GVDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
182-484 |
6.71e-141 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 420.59 E-value: 6.71e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 182 LAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQG 261
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGD--IDELTWRDVSGILNRGGTILGTSRSKPFKTEEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 262 RLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSslldelvknktitteqqekfnvLHIVGLVGSIDNDFCGTDMTIG 341
Cdd:pfam00365 80 REKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG----------------------IPVVGIPKTIDNDIPGTDYTIG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 342 TDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVdwpDRLCSQLaQERSAGQRL 421
Cdd:pfam00365 138 FDTALNTIVEAIDRIRDTASSHNRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDI---EELCEKI-KELRKGKRF 213
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17647809 422 NIVIVAEGAMDreghpitAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEA 484
Cdd:pfam00365 214 SIIVVAEGASD-------GEFLAKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKA 269
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
180-536 |
1.36e-130 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 395.99 E-value: 1.36e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRER 259
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGD--IVKLDLKSVSDIINRGGTILGSARFPEFKDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 QGRLKAANNLIQRGITNLVVIGGDGSLTGANLFrqewsslldelvknktitTEqqEKFNVlhiVGLVGSIDNDFCGTDMT 339
Cdd:PRK03202 80 EGRAKAIENLKKLGIDALVVIGGDGSYMGAKRL------------------TE--HGIPV---IGLPGTIDNDIAGTDYT 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVdwpDRLCSQLAQERSAGQ 419
Cdd:PRK03202 137 IGFDTALNTAVEAIDRLRDTASSHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDI---EELCAKIKKGRERGK 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 420 RLNIVIVAEGAMDreghpitAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVV 499
Cdd:PRK03202 214 KHAIIVVAEGVMP-------AEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGG---RM 283
|
330 340 350
....*....|....*....|....*....|....*..
gi 17647809 500 ISLDGNQAVRVPLMECVERTQAVAKamaeKRWADAVK 536
Cdd:PRK03202 284 VGIQNNKIVHVPIEEAVENMKHPFD----KDLYELAK 316
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
182-522 |
4.60e-121 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 372.10 E-value: 4.60e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 182 LAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQG 261
Cdd:COG0205 4 IGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGD--IIDLTREDVSGILQRGGTILGSSRSKPFKTEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 262 RLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWSslldelvknktitteqqekfnvLHIVGLVGSIDNDFCGTDMTIG 341
Cdd:COG0205 82 REKALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG----------------------IPVVGIPKTIDNDLPGTDYTIG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 342 TDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVdwpDRLCSQLAQERSAGQRL 421
Cdd:COG0205 140 FDTAVNTAAEAIDRLRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDL---DKLLEKLKERRKRGKGY 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 422 NIVIVAEGAMDREGHPI---------------TAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATL 486
Cdd:COG0205 217 SIIVVAEGAGDEDGEAVleadtdafghvrlggIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVE 296
|
330 340 350
....*....|....*....|....*....|....*.
gi 17647809 487 ALMEATKDsvpVVISLDGNQAVRVPLMECVERTQAV 522
Cdd:COG0205 297 LLLEGKTG---VMVGIRRGEIVLVPLEEVANKEKPV 329
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
573-856 |
5.20e-110 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 340.09 E-value: 5.20e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP---EGKF 649
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPfktEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 650 KEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQ 729
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 730 SAQGTkRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHmaskMAEGVSRGLILRNEKASEnysTD 809
Cdd:pfam00365 155 TASSH-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKE----LRKGKRFSIIVVAEGASD---GE 226
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 17647809 810 FIYRLYsEEGKGlFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVD 856
Cdd:pfam00365 227 FLAKLI-EEGTG-IETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
182-514 |
9.57e-110 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 340.87 E-value: 9.57e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 182 LAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQG 261
Cdd:TIGR02482 2 IGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGK--IEPLESKNVSGIIHRGGTILGTARCPEFKTEEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 262 RLKAANNLIQRGITNLVVIGGDGSLTGANLFRQEwsslldelvknktitteqqekfNVLHIVGLVGSIDNDFCGTDMTIG 341
Cdd:TIGR02482 80 REKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEE----------------------GGIPVIGLPGTIDNDIPGTDYTIG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 342 TDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPpkVDwPDRLCSQLAQERSAGQRL 421
Cdd:TIGR02482 138 FDTALNTIIDAVDKIRDTATSHERAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFD--YD-IDELIQRLKEQHEAGKKH 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 422 NIVIVAEGAMDREGHpitaeDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVIS 501
Cdd:TIGR02482 215 SIIIVAEGNIVGSAK-----EVAKKIEEKTGIETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGG---VMIG 286
|
330
....*....|...
gi 17647809 502 LDGNQAVRVPLME 514
Cdd:TIGR02482 287 IQNNKIVTHPIEE 299
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
180-526 |
2.09e-105 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 330.14 E-value: 2.09e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRER 259
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGD--IVPLDRYSVSDIINRGGTFLGSARFPEFKDE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 QGRLKAANNLIQRGITNLVVIGGDGSLTGANLFrqewsslldelvknktitTEqqEKFNVlhiVGLVGSIDNDFCGTDMT 339
Cdd:cd00763 79 EGQAKAIEQLKKHGIDALVVIGGDGSYMGAMRL------------------TE--HGFPC---VGLPGTIDNDIPGTDYT 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKvdwPDRLCSQLAQERSAGQ 419
Cdd:cd00763 136 IGFDTALNTVVEAIDRIRDTSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFD---REEVANRIKAGIERGK 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 420 RLNIVIVAEGAMDreghpitAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVV 499
Cdd:cd00763 213 KHAIVVVAEGVYD-------VDELAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGG---LA 282
|
330 340
....*....|....*....|....*..
gi 17647809 500 ISLDGNQAVRVPLMECVERTQAVAKAM 526
Cdd:cd00763 283 VGIQNEQLVHHDIIDAIENMKPFKKDW 309
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
182-516 |
2.29e-80 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 263.78 E-value: 2.29e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 182 LAVFTSGGDSQGMNAAVRACVRMAIY-LGCKVYFIREGYQGMVDGgDCIQEANWASVSSIIHRGGTIIGSARCQDFR-ER 259
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAIAeYGWEVIGIRDGWRGLLEG-DTVPLLDLEDVRGILPRGGTILGSSRTNPFKyEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 QGRLKAANNLIQRGITNLVVIGGDGSLTGANLFRQewsslldelvknktitteqqekfNVLHIVGLVGSIDNDFCGTDMT 339
Cdd:TIGR02483 81 DGDDKIVANLKELGLDALIAIGGDGTLGIARRLAD-----------------------KGLPVVGVPKTIDNDLEATDYT 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVdwpDRLCSQLAQERSAGQ 419
Cdd:TIGR02483 138 FGFDTAVEIATEALDRLHTTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEIPFDI---DSVCEKVRERFARGK 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 420 RLNIVIVAEGAMDREGHPITAEDVKKV----------------IDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAE 483
Cdd:TIGR02483 215 RFAIVVVAEGAKPKGGEMVVQEGVKDAfghvrlggignwlaeeIERRTGIETRATVLGHLQRGGSPSAFDRVLATRFGVA 294
|
330 340 350
....*....|....*....|....*....|...
gi 17647809 484 ATLALMEATKDsvpVVISLDGNQAVRVPLMECV 516
Cdd:TIGR02483 295 AVDLVHEGQFG---HMVALRGTDIVYVPIAEAV 324
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
573-860 |
5.26e-58 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 203.00 E-value: 5.26e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP---EGKF 649
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPfktEEGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 650 KEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQ 729
Cdd:COG0205 83 EKALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG------IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 730 SAQGTkRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASK--------MAEGVSRGLIlrnEK 801
Cdd:COG0205 157 TAASH-ERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRgkgysiivVAEGAGDEDG---EA 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17647809 802 ASENYSTDFIYRLYSEEGKGL---------FTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAA 860
Cdd:COG0205 233 VLEADTDAFGHVRLGGIGEYLakeieertgIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLE 300
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
573-858 |
1.19e-56 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 199.06 E-value: 1.19e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRT----LPEGk 648
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCkefrTEEG- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 649 FKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 728
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQG-FNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 729 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQdvyhMASKMAEGVSRG----LILRNEKAse 804
Cdd:cd00363 160 DTAS-SHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEE----MVDVIKKRRERGkrhgIVIVAEGA-- 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17647809 805 nysTDFIYRLYSEEG-------KGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWL 858
Cdd:cd00363 233 ---IDFIPKPITEKLlaklveeRLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELL 290
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
573-859 |
3.13e-55 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 194.14 E-value: 3.13e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTlPEGKFKEI 652
Cdd:PRK03202 3 RIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARF-PEFKDEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 653 AAR----LKEFKIQGLLIIGGFESYHAAGQIADQRdnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 728
Cdd:PRK03202 82 RAKaienLKKLGIDALVVIGGDGSYMGAKRLTEHG-------IPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 729 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLqqdvyhmASKMAEGVSRG----LILRNEKA-S 803
Cdd:PRK03202 155 DTAS-SHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEEL-------CAKIKKGRERGkkhaIIVVAEGVmP 226
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 17647809 804 ENYSTDFIyrlyseEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLA 859
Cdd:PRK03202 227 AEELAKEI------EERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLL 276
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
180-522 |
1.52e-53 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 191.05 E-value: 1.52e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAI-YLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQD--- 255
Cdd:PRK14071 5 KRIGILTSGGDCAGLNAVIRAVVHRARgTYGWEVIGIRDATQGLMARPPQYIELDLDQVDDLLRMGGTILGTTNKGDpfa 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 256 FRERQGRLKAANNLI-----QRGITNLVVIGGDGSLtganlfrqewsSLLDELVknktitteQQEKFNvlhIVGLVGSID 330
Cdd:PRK14071 85 FPMPDGSLRDRSQEIidgyhSLGLDALIGIGGDGSL-----------AILRRLA--------QQGGIN---LVGIPKTID 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 331 NDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPKVdwpDRLCSQ 410
Cdd:PRK14071 143 NDVGATEVSIGFDTAVNIATEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTL---ENVCKK 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 411 LAQERSAGQRLNIVIVAEGAMDREGHPITAED-------------VKKVIDERLKHDARITVLGHVQRGGNPSAFDRILA 477
Cdd:PRK14071 220 IRERQEEGKNFCLVVVSEAVRTEEGEQVTKTQalgedryggigqyLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLA 299
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 17647809 478 CRMGAEATLALMEATKDSvpvVISLDGNQAVRVPLMECVERTQAV 522
Cdd:PRK14071 300 SAFGVAAVDLIAQGKFDR---MVAWQNRQVVSVPIAEAIATYRAV 341
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
573-914 |
1.62e-53 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 189.54 E-value: 1.62e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRtLPEGKFKEI 652
Cdd:cd00763 2 RIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSAR-FPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 653 AAR----LKEFKIQGLLIIGGFESYHAAGQIADQRdnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 728
Cdd:cd00763 81 QAKaieqLKKHGIDALVVIGGDGSYMGAMRLTEHG-------FPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 729 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVyhmASKMAEGVSRGLILRNEKAsenYST 808
Cdd:cd00763 154 DTSS-SHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRI---KAGIERGKKHAIVVVAEGV---YDV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 809 DFIYRLYSEEGKglFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAqikaniDANGVVnckspdtatlLGIVSR 888
Cdd:cd00763 227 DELAKEIEEATG--FETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLA------GKGGLA----------VGIQNE 288
|
330 340
....*....|....*....|....*.
gi 17647809 889 QYRFSPLVDLIAEtnfdQRIPKKQWW 914
Cdd:cd00763 289 QLVHHDIIDAIEN----MKPFKKDWL 310
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
173-557 |
2.56e-40 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 159.99 E-value: 2.56e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 173 PVKPFKDKGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSAR 252
Cdd:cd00764 383 PLPEKTNLNIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQ--IVELGWIDVGGWTGRGGSELGTKR 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 253 C---QDFRErqgrlkAANNLIQRGITNLVVIGGDGSLTGanlfrqewsslLDELVKNKtittEQQEKFNVLHIVgLVGSI 329
Cdd:cd00764 461 TlpkKDLET------IAYNFQKYGIDGLIIVGGFEAYKG-----------LLQLREAR----EQYEEFCIPMVL-IPATV 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 330 DNDFCGTDMTIGTDTALHRIIEAIDAISSTAYS-HQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMP-----PKVDW 403
Cdd:cd00764 519 SNNVPGTDFSLGSDTALNALMKYCDRIKQSASGtKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPfnirdLQENV 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 404 pDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIderlkhDARITVLGHVQRGGNPSAFDRILACRMGAE 483
Cdd:cd00764 599 -EHLTEKMKTTIGRGLVLRNEKCNENYTTVFTYELYSEEGKGVF------DCRTNVLGHVQQGGAPSPFDRNFGTKFAVK 671
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17647809 484 ATLALMEATKDSvpvviSLDGNQAVRVPLMECVE--RTQAVAKAMAEKRWADAVKLRGRSFERNLE---TYKMLTRLKP 557
Cdd:cd00764 672 AMKWIEQKLKEN-----YAAGNEFANDPDFNCVNgvKKYAVLFEPVEELKQTTFEHRIPKEQWWLSlrpLLKILAKYKI 745
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
183-547 |
2.85e-28 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 119.38 E-value: 2.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 183 AVFTSGGDSQGMNAAVRACVRMAIY-LGCK-VYFIREGYQGMVdggdciqEANW-----ASVSSIIHRGGTIIGSARCQD 255
Cdd:PTZ00286 91 GIVTCGGLCPGLNVVIRELVMNLINnYGVKtIYGAKYGYKGLY-------KEDWikldpKDVKTIHRLGGTILGSSRGGF 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 256 FRErqgrlKAANNLIQRGITNLVVIGGDGSLTGANlfrqewsSLLDELVKNK-TITteqqekfnvlhIVGLVGSIDNDFC 334
Cdd:PTZ00286 164 DPK-----VMVDTLIRHGINILFTLGGDGTHRGAL-------AIYKELRRRKlNIS-----------VVGIPKTIDNDIP 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 335 GTDMTIGTDTALHRIIEAIDAISSTAYSHQRTF-IMEVMGRHCGYLALVGGLAC-EADFIFIPEMppkvDWPDRLCSQLA 412
Cdd:PTZ00286 221 IIDESFGFQTAVEEAQNAIRAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASaDVNVCLIPEF----DIPLEGVLEYI 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 413 QERSAGQRLNIVIVAEGAMD--REGHPITAED-------------VKKVIDERLKHDARITVLGHVQ-----RGGNPSAF 472
Cdd:PTZ00286 297 EQRLQKKGHCVIVVAEGAGQslKDADLDLGTDasgnkklwdigvyLKDEITKYLKKKKPEHTVKYIDpsymiRAVPANAA 376
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17647809 473 DRILACRMgaeATLALMEATKDSVPVVISLDGNQAVRVPLmecvertqavaKAMAEKrWADAVKLRGRSFERNLE 547
Cdd:PTZ00286 377 DAKFCTQL---AQNAVHGAMAGFTGFIIGHVHNNYVMIPI-----------KEMSGN-YRRRVNPEGRLWQRMLA 436
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
570-860 |
4.29e-25 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 108.23 E-value: 4.29e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 570 EGYRLAVMHIGAPACGMNAAVRSFVRNAIYR-GDVVYGINDGVEGLIAG--NVRELGWSDVSGWVGQGGAYLGTKRT--- 643
Cdd:PRK14071 3 EKKRIGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNKgdp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 644 ----LPEGKFK----EIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDT 715
Cdd:PRK14071 83 fafpMPDGSLRdrsqEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQGG------INLVGIPKTIDNDVGATEVSIGFDT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 716 GLNEITEICDRIRQSAqGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLqqdVYHMASKMAEGVSRGL 795
Cdd:PRK14071 157 AVNIATEALDRLHFTA-ASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENV---CKKIRERQEEGKNFCL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 796 ILRNE--KASENYSTDFIYRL----------YSEEGKGLFT---CRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAA 860
Cdd:PRK14071 233 VVVSEavRTEEGEQVTKTQALgedryggigqYLAEQIAERTgaeTRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQ 312
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
183-430 |
3.37e-23 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 103.80 E-value: 3.37e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 183 AVFTSGGDSQGMNAAVRACVRMAIYL-GCK-VYFIREGYQGMV-DGGDCIQEANWASVSSIIHRGGTIIGSAR-CQDFRE 258
Cdd:PRK06830 84 AIVTCGGLCPGLNDVIRAIVLELHHHyGVRrILGIRYGYQGLIpRYGHDPVELTPEVVADIHEFGGTILGSSRgPQDPEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 259 rqgrlkAANNLIQRGITNLVVIGGDGSLTGANLFRQEwsslldelvknktiTTEQQEKFNVlhiVGLVGSIDNDFCGTDM 338
Cdd:PRK06830 164 ------IVDTLERMNINILFVIGGDGTLRGASAIAEE--------------IERRGLKISV---IGIPKTIDNDINFIQK 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 339 TIGTDTALHRIIEAIDAISSTAYSHQRTF-IMEVMGRHCGYLALVGGLAC-EADFIFIPEMPPKVDWPDRLCSQLaQERS 416
Cdd:PRK06830 221 SFGFETAVEKATEAIRCAHVEANGAPNGIgLVKLMGRHSGFIAAYAALASkDVNFVLIPEVPFDLEGPNGLLAAL-EKRL 299
|
250
....*....|....
gi 17647809 417 AGQRLNIVIVAEGA 430
Cdd:PRK06830 300 AERGHAVIVVAEGA 313
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
183-484 |
4.65e-15 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 78.31 E-value: 4.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 183 AVFTSGGDSQGMNAAVRACV-RMAIYLGCKVYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARcqdfrerqG 261
Cdd:PLN02884 57 AIVTCGGLCPGLNDVIRQIVfTLEIYGVKNIVGIPFGYRGFFEKGLSEMPLSRKVVQNIHLSGGSLLGVSR--------G 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 262 RLKAA---NNLIQRGITNLVVIGGDGSLTGANLFRQEWsslldelvknktitteQQEKFNVLhIVGLVGSIDNDFCGTDM 338
Cdd:PLN02884 129 GAKTSdivDSIEARGINMLFVLGGNGTHAGANAIHNEC----------------RKRKMKVS-VVGVPKTIDNDILLMDK 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 339 TIGTDTALHriiEAIDAISStAYSHQRTF-----IMEVMGRHCGYLALVGGLAC-EADFIFIPEMPPKVDWPDRLCSQLa 412
Cdd:PLN02884 192 TFGFDTAVE---EAQRAINS-AYIEAHSAyhgigLVKLMGRSSGFIAMHASLASgQVDICLIPEVPFTLDGPNGVLRHL- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 413 QERSAGQRLNIVIVAEGA----------MDREGHPITAEDVKKVIDERLKHDARITVLGHVQ--------RGGNPSAFDR 474
Cdd:PLN02884 267 EHLIETKGSAVVCVAEGAgqdllqktnaTDASGNPVLGDIGVHLQQEIKKHFKDIGVPADVKyidptymiRACRANASDA 346
|
330
....*....|
gi 17647809 475 ILACRMGAEA 484
Cdd:PLN02884 347 ILCTVLGQNA 356
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
183-430 |
2.02e-14 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 77.10 E-value: 2.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 183 AVFTSGGDSQGMNAAVR--ACVRMAIYLGCKVYFIREGYQGMVDGGDCiqEANWASVSSIIHRGGTIIGSARC-QDFRer 259
Cdd:PLN02564 91 CIVTCGGLCPGLNTVIReiVCGLSYMYGVTRILGIDGGYRGFYSRNTI--PLTPKVVNDIHKRGGTILGTSRGgHDTS-- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 260 qgrlKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWsslldelvknktitteQQEKFNVLhIVGLVGSIDNDFCGTDMT 339
Cdd:PLN02564 167 ----KIVDSIQDRGINQVYIIGGDGTQKGASVIYEEI----------------RRRGLKVA-VAGIPKTIDNDIPVIDKS 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 340 IGTDTALHRIIEAIDAISSTAYS-HQRTFIMEVMGRHCGYLALVGGLAC-EADFIFIPEMPPKVDWPDRLCSQLAQERSA 417
Cdd:PLN02564 226 FGFDTAVEEAQRAINAAHVEAESvENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPFYLEGKGGLFEFIEKRLKE 305
|
250
....*....|...
gi 17647809 418 GQRLNIViVAEGA 430
Cdd:PLN02564 306 NGHMVIV-VAEGA 317
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
585-752 |
7.64e-13 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 72.00 E-value: 7.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 585 GMNAAVRSFVRNAIYRGDV--VYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRtlpeGKF--KEIAARLKEFK 660
Cdd:PTZ00286 101 GLNVVIRELVMNLINNYGVktIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSR----GGFdpKVMVDTLIRHG 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 661 IQGLLIIGGFESYHAAGQIADQ--RDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRV 738
Cdd:PTZ00286 177 INILFTLGGDGTHRGALAIYKElrRRKLN---ISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAYVEAKSAKNGV 253
|
170
....*....|....
gi 17647809 739 FVIETMGGYCGYLA 752
Cdd:PTZ00286 254 GIVKLMGRDSGFIA 267
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
320-500 |
1.40e-12 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 70.66 E-value: 1.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 320 LHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAI--DAISSTAY-SHQRTFIMEVMGRHCGYLALVGGLACE-----ADF 391
Cdd:PRK14072 133 IRCIGIPKTIDNDLPGTDHCPGFGSAAKYIATSVleAALDVAAMaNTSKVFILEVMGRHAGWLAAAAALAKQnpddaPHL 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 392 IFIPEMPPKVDwpdrlcSQLAQERSAGQRLN--IVIVAEGAMDREGHPI----TAED-------------VKKVIDERLK 452
Cdd:PRK14072 213 IYLPERPFDEE------KFLADVRAIVKRYGycVVVVSEGIRDADGKFIaeagLAEDafghaqlggvapvLANLIKEKLG 286
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 17647809 453 HDARITVLGHVQR--GGNPSAFDRILACRMGAEATLALMeATKDSVPVVI 500
Cdd:PRK14072 287 KKVHWAVLDYLQRaaRHIASKTDVEEAYAVGKAAVEYAL-AGKNGVMPAI 335
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
180-486 |
6.26e-10 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 62.33 E-value: 6.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 180 KGLAVFTSGGDSQGMNAAVRACVRMAIYLGCKVYFI--REGYQGMVdGGDCIQ-----EANwasvSSIIHR-GGTIIGSA 251
Cdd:PRK06555 4 KKVALLTAGGLAPCLSSAVGGLIERYTEIAPEVEIIayRSGYQGLL-LGDSIEitpavRAN----AGLLHRyGGSPIGNS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 252 R--------CQD---FRERQGRLK-AANNLIQRGITNLVVIGGDGSLTGAnlfrqewSSLLDELVKNKTITTeqqekfnv 319
Cdd:PRK06555 79 RvkltnvadCVKrglVKEGENPLKvAAERLAADGVDILHTIGGDDTNTTA-------ADLAAYLAENGYDLT-------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 320 lhIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIM-EVMGRHCGYLA---------------LVG 383
Cdd:PRK06555 144 --VVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTaatarayrewldrqeYVP 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 384 GLACEADF-----IFIPEMPPKVDwpdrlcsqlaqerSAGQRLNIVivaegaMDREG------------HPITAEDVKKv 446
Cdd:PRK06555 222 GFGLSAERwdihaVYLPEMAFDLE-------------AEAERLKAV------MDEVGnvniflsegaglDAIVAEMEAA- 281
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 17647809 447 iDERLKHDAritvLGHVQRGG-NPSA-FDRILACRMGAEATL 486
Cdd:PRK06555 282 -GEEVKRDA----FGHVKLDTiNPGAwFAKQFAELLGAEKVM 318
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
585-753 |
1.19e-06 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 52.18 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 585 GMNAAVRSFVRNAIYRGDV--VYGINDGVEGLIAG---NVRELGWSDVSGWVGQGGAYLGTKR--TLPEgkfkEIAARLK 657
Cdd:PRK06830 94 GLNDVIRAIVLELHHHYGVrrILGIRYGYQGLIPRyghDPVELTPEVVADIHEFGGTILGSSRgpQDPE----EIVDTLE 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 658 EFKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTK 735
Cdd:PRK06830 170 RMNINILFVIGGDGTLRGASAIAEeiERRGLK---ISVIGIPKTIDNDINFIQKSFGFETAVEKATEAIRCAHVEANGAP 246
|
170
....*....|....*...
gi 17647809 736 RRVFVIETMGGYCGYLAT 753
Cdd:PRK06830 247 NGIGLVKLMGRHSGFIAA 264
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
585-752 |
9.40e-06 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 49.36 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 585 GMNAAVRSFV--RNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKR----TlpegkfKEIAARLKE 658
Cdd:PLN02564 101 GLNTVIREIVcgLSYMYGVTRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTSRgghdT------SKIVDSIQD 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 659 FKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKR 736
Cdd:PLN02564 175 RGINQVYIIGGDGTQKGASVIYEeiRRRGLK---VAVAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESVEN 251
|
170
....*....|....*.
gi 17647809 737 RVFVIETMGGYCGYLA 752
Cdd:PLN02564 252 GIGLVKLMGRYSGFIA 267
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
152-432 |
1.83e-05 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 48.88 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 152 KSVDELRKCLRTMQDVidfvhPVKPFKD-------KG-----LAVFTSGGDSQGMNAAVRAcvrmaIYLGCKVYFIREGY 219
Cdd:PTZ00287 143 KDYEEVKRFLKNLHNL-----PILNVKEtnnhesfKGgnvlkIGIILSGGPAPGGHNVISG-----IYDYAKRYNEQSQV 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 220 QGMVDGGDCIQEANWASVS-SIIHR-----GGTIIGSARCQdFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGAnlfr 293
Cdd:PTZ00287 213 IGFLGGIDGLYSKNYVTITdSLMNRfrnlgGFNMLWSGRGK-VRNKDDLIAIENIVAKLKLNGLVIIGGDGSNSNA---- 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 294 qewsSLLDELVKNKTITteqqekfnvLHIVGLVGSIDNDFC--GTDMTIGTDTALHRIIEAIDAISSTAYS-HQRTFIME 370
Cdd:PTZ00287 288 ----ALISEYFAERQIP---------ISIIGIPKTIDGDLKseAIEISFGFDTATKTYSEVIGNLCTDVKTgHNVYHVVR 354
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17647809 371 VMGRHCGYLALVGGLACEADFIFIPEMPPKV-----DWPDRLCSQLAQERSAGQRLNIVIVAEGAMD 432
Cdd:PTZ00287 355 VMGRSASHVVLECALQTRPNIVLIGEEVEKEnlslkDIVSNIVNTILKRRSLNKNYGVILIPEGLIE 421
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
237-432 |
4.89e-05 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 47.28 E-value: 4.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 237 VSSIIHRGG-TIIGSARCQDFRERQgrLKAANNLIQR-GITNLVVIGGDGSLTGANL----FRQEWSSLLdelvknktit 310
Cdd:PTZ00468 160 INGILNQGGfNIICSGRHKIETEEQ--MRASLEICEKlKLHGLVVIGGDDSNTNAAVlaeyFKRNSSSTV---------- 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 311 teqqekfnvlhIVGLVGSIDNDFCG--TDMTIGTDTALHRIIEAIDAI-SSTAYSHQRTFIMEVMGRHCGYLALVGGLAC 387
Cdd:PTZ00468 228 -----------VVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQIGSImDAIKTEGYGYYFVRLMGRSASHITLECGLQT 296
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 17647809 388 EADFIFIPEMPPKVDWP-----DRLCSQLAQERSAGQRLNIVIVAEGAMD 432
Cdd:PTZ00468 297 RANMILIGEEIKEENRSlmsivDEIVEMILKRDSLGKKHGIVLLPEGLIE 346
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
244-432 |
5.55e-05 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 46.79 E-value: 5.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 244 GGTIIGSARCQDFRERQGRlKAANNLIQRGITNLVVIGGDGSLTGAnlfrqewsSLLDELVKNKTITTEqqekfnvlhIV 323
Cdd:cd00765 138 GFDMICSGRTKIETEDQFK-QAEETAKKLDLDALVVIGGDDSNTNA--------ALLAENFRSKGLKTR---------VI 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 324 GLVGSIDNDFCGTDMTI--GTDTALHRIIE-----AIDAISSTAYSHqrtFImEVMGRHCGYLALVGGLACEADFIFIPE 396
Cdd:cd00765 200 GVPKTIDGDLKNKEIETsfGFDTATKIYSElignvMRDARSTGKYWH---FV-KLMGRSASHIALECALKTHPNICIISE 275
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 17647809 397 MPPK-----VDWPDRLCSQLAQERSAGQRLNIVIVAEGAMD 432
Cdd:cd00765 276 EVSAqkqtlKNITDYMVDVICKRAELGYNFGVVLVPEGLIE 316
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
573-745 |
6.47e-04 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 43.37 E-value: 6.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 573 RLAVMHIGAPA-------CGMNAAVRSFVRNAiyrgdVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGG-AYLGTKRTL 644
Cdd:PRK07085 72 KVGVILSGGQApgghnviAGLFDGLKKLNPDS-----KLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGRTK 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 645 PEGK--FKEIAARLKEFKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGT--EFSLGCDTGLN 718
Cdd:PRK07085 147 IETEeqKEACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfAKHGCK---TQVIGVPKTIDGDLKNEfiETSFGFDTATK 223
|
170 180
....*....|....*....|....*..
gi 17647809 719 EITEICDRIRQSAQGTKRRVFVIETMG 745
Cdd:PRK07085 224 TYSEMIGNISRDALSAKKYWHFIKLMG 250
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
247-429 |
1.06e-03 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 42.60 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 247 IIGSARCQDFRERQgRLKAANNLIQRGITNLVVIGGDGSLTGAnlfrqewsSLLDELVKNKTITTEqqekfnvlhIVGLV 326
Cdd:PRK07085 139 MIGSGRTKIETEEQ-KEACLETVKKLKLDGLVIIGGDDSNTNA--------AILAEYFAKHGCKTQ---------VIGVP 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17647809 327 GSIDNDFCGT--DMTIGTDTALHRIIEAI-----DAISSTAYSHqrtFImEVMGRHCGYLALVGGLACEADFIFIPE--- 396
Cdd:PRK07085 201 KTIDGDLKNEfiETSFGFDTATKTYSEMIgnisrDALSAKKYWH---FI-KLMGRSASHIALECALQTHPNICLISEeva 276
|
170 180 190
....*....|....*....|....*....|....*.
gi 17647809 397 ---MPPKvDWPDRLCSQLAQERSAGQRLNIVIVAEG 429
Cdd:PRK07085 277 ekkMSLQ-DIVHYIASVIADRAAKGKNYGVILIPEG 311
|
|
| |
