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Conserved domains on  [gi|17550422|ref|NP_509720|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 8-314 8.24e-96

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 287.04  E-value: 8.24e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422     8 NIFSKNGFCASFLTNFFVIYLTTFFVKNLIGTYKKMILIFSLLGILFSGIEILARPFAHNYNNSLMFF-SLNFWTSSQTL 86
Cdd:pfam10326   2 HIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    87 PEFFISVWAGLYVTILAFIAVQFVYRYSCLMNTNVMELFDGFGGVLLMMYPILPGVIYSCVFYLFCLPDNISDSYVQDEI 166
Cdd:pfam10326  82 GQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREEL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   167 FENYGLIIKEIPRFIALTYNLNET----IRWNSIYFFLSAVSLISIHYAIMFYFGLKMHFNMKQQLLKFSSKNRKLQRQF 242
Cdd:pfam10326 162 LENYNLDIDEVAYVGPVYYPTDENgskvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQL 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17550422   243 FKALIFQSIGPTVLLVLPAVPVLLCPVVAsffhfffSKFSWQTGWLYSFICFYPPFDSISFLMIVTEYRNII 314
Cdd:pfam10326 242 FKALVIQTLIPTILMYIPVGILFLLPLFN-------IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 8-314 8.24e-96

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 287.04  E-value: 8.24e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422     8 NIFSKNGFCASFLTNFFVIYLTTFFVKNLIGTYKKMILIFSLLGILFSGIEILARPFAHNYNNSLMFF-SLNFWTSSQTL 86
Cdd:pfam10326   2 HIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    87 PEFFISVWAGLYVTILAFIAVQFVYRYSCLMNTNVMELFDGFGGVLLMMYPILPGVIYSCVFYLFCLPDNISDSYVQDEI 166
Cdd:pfam10326  82 GQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREEL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   167 FENYGLIIKEIPRFIALTYNLNET----IRWNSIYFFLSAVSLISIHYAIMFYFGLKMHFNMKQQLLKFSSKNRKLQRQF 242
Cdd:pfam10326 162 LENYNLDIDEVAYVGPVYYPTDENgskvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQL 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17550422   243 FKALIFQSIGPTVLLVLPAVPVLLCPVVAsffhfffSKFSWQTGWLYSFICFYPPFDSISFLMIVTEYRNII 314
Cdd:pfam10326 242 FKALVIQTLIPTILMYIPVGILFLLPLFN-------IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 8-314 8.24e-96

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 287.04  E-value: 8.24e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422     8 NIFSKNGFCASFLTNFFVIYLTTFFVKNLIGTYKKMILIFSLLGILFSGIEILARPFAHNYNNSLMFF-SLNFWTSSQTL 86
Cdd:pfam10326   2 HIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    87 PEFFISVWAGLYVTILAFIAVQFVYRYSCLMNTNVMELFDGFGGVLLMMYPILPGVIYSCVFYLFCLPDNISDSYVQDEI 166
Cdd:pfam10326  82 GQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREEL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   167 FENYGLIIKEIPRFIALTYNLNET----IRWNSIYFFLSAVSLISIHYAIMFYFGLKMHFNMKQQLLKFSSKNRKLQRQF 242
Cdd:pfam10326 162 LENYNLDIDEVAYVGPVYYPTDENgskvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQL 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17550422   243 FKALIFQSIGPTVLLVLPAVPVLLCPVVAsffhfffSKFSWQTGWLYSFICFYPPFDSISFLMIVTEYRNII 314
Cdd:pfam10326 242 FKALVIQTLIPTILMYIPVGILFLLPLFN-------IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
 15-262 4.42e-21

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 91.92  E-value: 4.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    15 FCA-SFLTNFFVIYLTTFFVKNLIGTYKKMILIFSLLGILFSGIEILARPFAHNYNNSLMFFSLNFWTS-SQTLPEFFIS 92
Cdd:pfam10319  14 FGVlSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGPFFeYSELGQHALS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    93 VWAGLYVTILAFIAVQFVYRYSCLMNTNVMEL-FDGFGGVLLMMYPILPGVIYSCVFYLFCLPDNISDSYVQDEIFENYG 171
Cdd:pfam10319  94 ARCSFISASYAVLLIHFIYRYLVLFNPQLTRHyFRPWGILISILFFLFHGSVWTAICYFLLRANDEIRDYIREDFRETYG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   172 LIIKEIPRFIALTYNLNETIRWNSiYFFLSAVSLISIhYAIMFYF--GLKMHFNMKQQLLKFSSKNRKLQRQFFKALIFQ 249
Cdd:pfam10319 174 VDSMDINMLGALYWEASDETVFRS-WLGILLLTVISV-YSIILYIvlGYKIMRKLNKMSVTMSKKTKRLQKQLLKALIVQ 251

                         250
                  ....*....|...
gi 17550422   250 SIGPTVLLVLPAV 262
Cdd:pfam10319 252 TIIPICISFSPCV 264
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 15-267 3.14e-04

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 42.15  E-value: 3.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    15 FCASFLTNFFVIYLTTFFVKNLIGTYKKMILIFSLLGILFSGIEILARPFAHNYNNSLMFFSLNFWTS-SQTLPEFFISV 93
Cdd:pfam10317   9 FILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYfGPWFCYSGYSL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    94 WAGLYVTILAFIAVQFVYRYSCLMNTNVMELfdgfGGVLLMMYPILPGVIYSCVFYLFcLPDNISDSYVQDEIFENYGLI 173
Cdd:pfam10317  89 LQHFLLHSGWSLLLTFYYRYYILKHVDPKRK----KLILLIIIHYIPSLSQLIVIFLS-PTDFLPVEALTKELHPNYNLT 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   174 IKEIPRFIALTYnlnetirWNSIYFFLSAVSLISIHYAIMFYFGLKMHFNMKQQLLKFSSKNRKLQRQFFKALIFQSIGP 253
Cdd:pfam10317 164 DYTVTGFSDLQS-------FPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLP 236

                         250
                  ....*....|....
gi 17550422   254 TVLLVLPAVPVLLC 267
Cdd:pfam10317 237 LFSYIPGVTLYLLS 250
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 89-262 2.19e-03

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 39.45  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422    89 FFISVWAGLYVTILAFiavqFVYRYSCLMNTNVMELFdGFGGVLLMMYPILPGVIYSCVFYLFcLPDniSDSYVQdEIFE 168
Cdd:pfam10318  91 IGVTSLALVGVSIILL----FENRYSILFTNKKRITW-KKTRVLYLIFNYIIALLFLIPIYLN-IPD--QEAAKL-KVLK 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17550422   169 NYGLIIKEIPRfIALTYNLNETIRWNSIYFFLSAVSLISihyAIMFYFGLKMHFNMKQQLLKFSSKNRKLQRQFFKALIF 248
Cdd:pfam10318 162 KLPCLPPEFFD-NPPVFVLAIDSTYFLICIVLLILILII---QILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALII 237

                         170
                  ....*....|....
gi 17550422   249 QSIGPTVLLVLPAV 262
Cdd:pfam10318 238 QVSIPLIVILIPLI 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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