NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17551128|ref|NP_509155|]
View 

Neuronal immunoglobulin domain-containing protein rig-3 [Caenorhabditis elegans]

Protein Classification

IG_like and Ig domain-containing protein( domain architecture ID 12208774)

IG_like and Ig domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Ig cd00096
Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found ...
 267-331 7.72e-07

Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, including T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, including butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond. Ig superfamily (IgSF) domains can be divided into 4 main classes based on their structures and sequences: the Variable (V), Constant 1 (C1), Constant 2 (C2), and Intermediate (I) sets. Typically, the V-set domains have A, B, E, and D strands in one sheet and A', G, F, C, C' and C" in the other. The structures in C1-set are smaller than those in the V-set; they have one beta sheet that is formed by strands A, B, E, and D and the other by strands G, F, C, and C'. Moreover, a C1-set Ig domain contains a short C' strand (three residues) and lacks A' and C" strand. Unlike other Ig domain sets, C2-set structures do not have a D strand. Like the V-set Ig domains, members of the I-set have a discontinuous A strand, but lack a C" strand.


:

Pssm-ID: 409353 [Multi-domain]  Cd Length: 70  Bit Score: 46.55  E-value: 7.72e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17551128 267 AIIYCNVTHSFPPvrHYTFYHGDEEIKMSDKFNIFVNVGVSqgaHLKIHNVNENDLGTYKCEANN 331
Cdd:cd00096   1 VTLTCSASGNPPP--TITWYKNGKPLPPSSRDSRRSELGNG---TLTISNVTLEDSGTYTCVASN 60
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 48-142 1.39e-06

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


:

Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 46.34  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128     48 TITVREGKKLMVSCVFESDEQIHKSdllWKQANGNNIDGESNpslFSVIlnekgSKHRKTSLHFSSVHTRDTGLYTCTGR 127
Cdd:smart00410   3 SVTVKEGESVTLSCEASGSPPPEVT---WYKQGGKLLAESGR---FSVS-----RSGSTSTLTISNVTPEDSGTYTCAAT 71

                           90
                   ....*....|....*
gi 17551128    128 TAGGeNFEKTIKLVV 142
Cdd:smart00410  72 NSSG-SASSGTTLTV 85
 
Name Accession Description Interval E-value
Ig cd00096
Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found ...
 267-331 7.72e-07

Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, including T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, including butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond. Ig superfamily (IgSF) domains can be divided into 4 main classes based on their structures and sequences: the Variable (V), Constant 1 (C1), Constant 2 (C2), and Intermediate (I) sets. Typically, the V-set domains have A, B, E, and D strands in one sheet and A', G, F, C, C' and C" in the other. The structures in C1-set are smaller than those in the V-set; they have one beta sheet that is formed by strands A, B, E, and D and the other by strands G, F, C, and C'. Moreover, a C1-set Ig domain contains a short C' strand (three residues) and lacks A' and C" strand. Unlike other Ig domain sets, C2-set structures do not have a D strand. Like the V-set Ig domains, members of the I-set have a discontinuous A strand, but lack a C" strand.


Pssm-ID: 409353 [Multi-domain]  Cd Length: 70  Bit Score: 46.55  E-value: 7.72e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17551128 267 AIIYCNVTHSFPPvrHYTFYHGDEEIKMSDKFNIFVNVGVSqgaHLKIHNVNENDLGTYKCEANN 331
Cdd:cd00096   1 VTLTCSASGNPPP--TITWYKNGKPLPPSSRDSRRSELGNG---TLTISNVTLEDSGTYTCVASN 60
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 266-343 8.52e-07

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 46.73  E-value: 8.52e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17551128    266 DAIIYCNVThSFPPVRHYTFYHGDEEIKMSDKFNIFVNvgvSQGAHLKIHNVNENDLGTYKCEANNIKAKSYHTIHLR 343
Cdd:smart00410  11 SVTLSCEAS-GSPPPEVTWYKQGGKLLAESGRFSVSRS---GSTSTLTISNVTPEDSGTYTCAATNSSGSASSGTTLT 84
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 48-142 1.39e-06

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 46.34  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128     48 TITVREGKKLMVSCVFESDEQIHKSdllWKQANGNNIDGESNpslFSVIlnekgSKHRKTSLHFSSVHTRDTGLYTCTGR 127
Cdd:smart00410   3 SVTVKEGESVTLSCEASGSPPPEVT---WYKQGGKLLAESGR---FSVS-----RSGSTSTLTISNVTPEDSGTYTCAAT 71

                           90
                   ....*....|....*
gi 17551128    128 TAGGeNFEKTIKLVV 142
Cdd:smart00410  72 NSSG-SASSGTTLTV 85
ig pfam00047
Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of ...
 48-131 5.56e-05

Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions.


Pssm-ID: 395002  Cd Length: 86  Bit Score: 41.80  E-value: 5.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128    48 TITVREGKKLMVSCvfESDEQIHKSDLLWKQANGNNIDGESNPslfsvilnEKGSKHRKTSLHFSSVHTRDTGLYTCTGR 127
Cdd:pfam00047   5 TVTVLEGDSATLTC--SASTGSPGPDVTWSKEGGTLIESLKVK--------HDNGRTTQSSLLISNVTKEDAGTYTCVVN 74


                  ....
gi 17551128   128 TAGG 131
Cdd:pfam00047  75 NPGG 78
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 247-331 7.13e-05

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 41.01  E-value: 7.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128   247 PEFETEESVQYTVIDNHVRdaiIYCNVTHSFPPvrHYTFYHGDEEIKMSDKFNIFVNVGVSQgahLKIHNVNENDLGTYK 326
Cdd:pfam13927   2 PVITVSPSSVTVREGETVT---LTCEATGSPPP--TITWYKNGEPISSGSTRSRSLSGSNST---LTISNVTRSDAGTYT 73


                  ....*
gi 17551128   327 CEANN 331
Cdd:pfam13927  74 CVASN 78
 
Name Accession Description Interval E-value
Ig cd00096
Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found ...
 267-331 7.72e-07

Immunoglobulin domain; The members here are composed of the immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, including T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, including butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond. Ig superfamily (IgSF) domains can be divided into 4 main classes based on their structures and sequences: the Variable (V), Constant 1 (C1), Constant 2 (C2), and Intermediate (I) sets. Typically, the V-set domains have A, B, E, and D strands in one sheet and A', G, F, C, C' and C" in the other. The structures in C1-set are smaller than those in the V-set; they have one beta sheet that is formed by strands A, B, E, and D and the other by strands G, F, C, and C'. Moreover, a C1-set Ig domain contains a short C' strand (three residues) and lacks A' and C" strand. Unlike other Ig domain sets, C2-set structures do not have a D strand. Like the V-set Ig domains, members of the I-set have a discontinuous A strand, but lack a C" strand.


Pssm-ID: 409353 [Multi-domain]  Cd Length: 70  Bit Score: 46.55  E-value: 7.72e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17551128 267 AIIYCNVTHSFPPvrHYTFYHGDEEIKMSDKFNIFVNVGVSqgaHLKIHNVNENDLGTYKCEANN 331
Cdd:cd00096   1 VTLTCSASGNPPP--TITWYKNGKPLPPSSRDSRRSELGNG---TLTISNVTLEDSGTYTCVASN 60
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 266-343 8.52e-07

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 46.73  E-value: 8.52e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17551128    266 DAIIYCNVThSFPPVRHYTFYHGDEEIKMSDKFNIFVNvgvSQGAHLKIHNVNENDLGTYKCEANNIKAKSYHTIHLR 343
Cdd:smart00410  11 SVTLSCEAS-GSPPPEVTWYKQGGKLLAESGRFSVSRS---GSTSTLTISNVTPEDSGTYTCAATNSSGSASSGTTLT 84
IG_like smart00410
Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.
 48-142 1.39e-06

Immunoglobulin like; IG domains that cannot be classified into one of IGv1, IGc1, IGc2, IG.


Pssm-ID: 214653 [Multi-domain]  Cd Length: 85  Bit Score: 46.34  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128     48 TITVREGKKLMVSCVFESDEQIHKSdllWKQANGNNIDGESNpslFSVIlnekgSKHRKTSLHFSSVHTRDTGLYTCTGR 127
Cdd:smart00410   3 SVTVKEGESVTLSCEASGSPPPEVT---WYKQGGKLLAESGR---FSVS-----RSGSTSTLTISNVTPEDSGTYTCAAT 71

                           90
                   ....*....|....*
gi 17551128    128 TAGGeNFEKTIKLVV 142
Cdd:smart00410  72 NSSG-SASSGTTLTV 85
IgI_3_Contactin-1 cd05851
Third immunoglobulin (Ig) domain of contactin-1; member of the I-set of Ig superfamily (IgSF) ...
 309-338 5.20e-05

Third immunoglobulin (Ig) domain of contactin-1; member of the I-set of Ig superfamily (IgSF) domains; The members here are composed of the third immunoglobulin (Ig) domain of the neural cell adhesion molecule contactin-1. Contactins are comprised of six Ig domains followed by four fibronectin type III (FnIII) domains anchored to the membrane by glycosylphosphatidylinositol. Contactin-1 is differentially expressed in tumor tissues and may through a RhoA mechanism, facilitate invasion and metastasis of human lung adenocarcinoma. This group belongs to the I-set of IgSF domains.


Pssm-ID: 143259  Cd Length: 88  Bit Score: 41.93  E-value: 5.20e-05
                        10        20        30
                ....*....|....*....|....*....|
gi 17551128 309 GAHLKIHNVNENDLGTYKCEANNIKAKSYH 338
Cdd:cd05851  52 GAVLKIFNIQPEDEGTYECEAENIKGKDKH 81
ig pfam00047
Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of ...
 48-131 5.56e-05

Immunoglobulin domain; Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions. Examples include antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions.


Pssm-ID: 395002  Cd Length: 86  Bit Score: 41.80  E-value: 5.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128    48 TITVREGKKLMVSCvfESDEQIHKSDLLWKQANGNNIDGESNPslfsvilnEKGSKHRKTSLHFSSVHTRDTGLYTCTGR 127
Cdd:pfam00047   5 TVTVLEGDSATLTC--SASTGSPGPDVTWSKEGGTLIESLKVK--------HDNGRTTQSSLLISNVTKEDAGTYTCVVN 74


                  ....
gi 17551128   128 TAGG 131
Cdd:pfam00047  75 NPGG 78
V-set pfam07686
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 48-143 5.65e-05

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


Pssm-ID: 462230  Cd Length: 109  Bit Score: 42.45  E-value: 5.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128    48 TITVREGKKLMVSCVFESDEQIHKSDLLW-KQANGNNID-------GESNPSLFS--VILNEKGSKHrKTSLHFSSVHTR 117
Cdd:pfam07686   5 EVTVALGGSVTLPCTYSSSMSEASTSVYWyRQPPGKGPTfliayysNGSEEGVKKgrFSGRGDPSNG-DGSLTIQNLTLS 83

                          90       100
                  ....*....|....*....|....*.
gi 17551128   118 DTGLYTCTGRTAGGENFEKTIKLVVL 143
Cdd:pfam07686  84 DSGTYTCAVIPSGEGVFGKGTRLTVL 109
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 247-331 7.13e-05

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 41.01  E-value: 7.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128   247 PEFETEESVQYTVIDNHVRdaiIYCNVTHSFPPvrHYTFYHGDEEIKMSDKFNIFVNVGVSQgahLKIHNVNENDLGTYK 326
Cdd:pfam13927   2 PVITVSPSSVTVREGETVT---LTCEATGSPPP--TITWYKNGEPISSGSTRSRSLSGSNST---LTISNVTRSDAGTYT 73


                  ....*
gi 17551128   327 CEANN 331
Cdd:pfam13927  74 CVASN 78
I-set pfam07679
Immunoglobulin I-set domain;
266-331 1.21e-04

Immunoglobulin I-set domain;


Pssm-ID: 400151 [Multi-domain]  Cd Length: 90  Bit Score: 40.70  E-value: 1.21e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17551128   266 DAIIYCNVTHSFPPVrhYTFYHGDEEIKMSDKFNIFVNvgvSQGAHLKIHNVNENDLGTYKCEANN 331
Cdd:pfam07679  17 SARFTCTVTGTPDPE--VSWFKDGQPLRSSDRFKVTYE---GGTYTLTISNVQPDDSGKYTCVATN 77
Ig3_L1-CAM_like cd05731
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar ...
 312-343 1.83e-04

Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; The members here are composed of the third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM). L1 belongs to the L1 subfamily of cell adhesion molecules (CAMs) and is comprised of an extracellular region having six Ig-like domains and five fibronectin type III domains, a transmembrane region and an intracellular domain. L1 is primarily expressed in the nervous system and is involved in its development and function. L1 is associated with an X-linked recessive disorder, X-linked hydrocephalus, MASA syndrome, and spastic paraplegia type 1, that involves abnormalities of axonal growth. This group also contains the chicken neuron-glia cell adhesion molecule, Ng-CAM and human neurofascin.


Pssm-ID: 409394 [Multi-domain]  Cd Length: 83  Bit Score: 40.09  E-value: 1.83e-04
                        10        20        30
                ....*....|....*....|....*....|..
gi 17551128 312 LKIHNVNENDLGTYKCEANNIKAKSYHTIHLR 343
Cdd:cd05731  50 LKIENVSEADSGEYQCTASNTMGSARHTISVT 81
IgI_3_Contactin cd04968
Third immunoglobulin (Ig) domain of contactin; member of the I-set of Ig superfamily (IgSF) ...
 307-338 1.20e-03

Third immunoglobulin (Ig) domain of contactin; member of the I-set of Ig superfamily (IgSF) domains; The members here are composed of the third immunoglobulin (Ig) domain of contactins. Contactins are neural cell adhesion molecules and are comprised of six Ig domains followed by four fibronectin type III (FnIII) domains anchored to the membrane by glycosylphosphatidylinositol. The first four Ig domains form the intermolecular binding fragment, which arranges as a compact U-shaped module via contacts between Ig domains 1 and 4, and between Ig domains 2 and 3. Contactin-2 (TAG-1, axonin-1) may play a part in the neuronal processes of neurite outgrowth, axon guidance and fasciculation, and neuronal migration. This group also includes contactin-1 and contactin-5. The different contactins show different expression patterns in the central nervous system. During development and in adulthood, contactin-2 is transiently expressed in subsets of central and peripheral neurons. Contactin-5 is expressed specifically in the rat postnatal nervous system, peaking at about 3 weeks postnatal, and a lack of contactin-5 (NB-2) results in an impairment of neuronal activity in the rat auditory system. Contactin-5 is highly expressed in the adult human brain in the occipital lobe and in the amygdala. Contactin-1 is differentially expressed in tumor tissues and may, through a RhoA mechanism, facilitate invasion and metastasis of human lung adenocarcinoma. This group belongs to the I-set of IgSF domains.


Pssm-ID: 409357 [Multi-domain]  Cd Length: 88  Bit Score: 37.91  E-value: 1.20e-03
                        10        20        30
                ....*....|....*....|....*....|..
gi 17551128 307 SQGAHLKIHNVNENDLGTYKCEANNIKAKSYH 338
Cdd:cd04968  50 TSEPVLEIPNVQFEDEGTYECEAENSRGKDTV 81
V-set_CD47 pfam08204
CD47 immunoglobulin-like domain; This family represents the CD47 leukocyte antigen V-set like ...
 249-343 1.93e-03

CD47 immunoglobulin-like domain; This family represents the CD47 leukocyte antigen V-set like Ig domain.


Pssm-ID: 400488  Cd Length: 93  Bit Score: 37.44  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17551128   249 FETEESVQYTVIDNHVrdaIIYCNVTHsfppvrhyTFYHGDEEIKMSDKFN---IFVNVGVSQGAHLKIhNVNENDLGTY 325
Cdd:pfam08204   3 FNNTKSVEYTACNDTV---VIPCDVDN--------LEYNNISEVHVKWKFNnkdIFIFNGTNNISTLKF-DFSDALSGNY 70

                          90
                  ....*....|....*...
gi 17551128   326 KCEANNIKAKSYHTIHLR 343
Cdd:pfam08204  71 TCEVTELFNEGKTTIELK 88
IgI_Twitchin_like cd20949
C-terminal immunoglobulin-like domain of the myosin-associated giant protein kinase Twitchin, ...
 265-332 2.96e-03

C-terminal immunoglobulin-like domain of the myosin-associated giant protein kinase Twitchin, and similar domains; member of the I-set IgSF domains; The members here are composed of the C-terminal immunoglobulin-like domain of the myosin-associated giant protein kinase Twitchin and similar proteins, including Caenorhabditis elegans and Aplysia californica Twitchin, Drosophila melanogaster Projectin, and similar proteins. These are very large muscle proteins containing multiple immunoglobulin (Ig)-like and fibronectin type III (FN3) domains and a single kinase domain near the C-terminus. In humans these proteins are called Titin. The Ig superfamily (IgSF) is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. IgSF domains can be divided into 4 main classes based on their structures and sequences: the Variable (V), Constant 1 (C1), Constant 2 (C2), and Intermediate (I) sets. The Ig-like domain of the Twitchin is a member of the I-set IgSF domains, having A-B-E-D strands in one beta-sheet and A'-G-F-C-C' in the other. Like the V-set Ig domains, members of the I-set have a discontinuous A strand but lack a C" strand. I-set domains are found in several cell adhesion molecules (such as VCAM, ICAM, and MADCAM), and are also present in numerous other diverse protein families, including several tyrosine-protein kinase receptors, the hemolymph protein hemolin, the muscle proteins (titin, telokin, and twitchin), the neuronal adhesion molecule axonin-1, and the signaling molecule semaphorin 4D.


Pssm-ID: 409541 [Multi-domain]  Cd Length: 89  Bit Score: 36.93  E-value: 2.96e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17551128 265 RDAIIYCNVTHSFPPVrhYTFYHGDEEIKMSDKFNIFVNvGVSQGahLKIHNVNENDLGTYKCEANNI 332
Cdd:cd20949  15 QSATILCEVKGEPQPN--VTWHFNGQPISASVADMSKYR-ILADG--LLINKVTQDDTGEYTCRAYQV 77
Ig_3 pfam13927
Immunoglobulin domain; This family contains immunoglobulin-like domains.
 47-125 8.15e-03

Immunoglobulin domain; This family contains immunoglobulin-like domains.


Pssm-ID: 464046 [Multi-domain]  Cd Length: 78  Bit Score: 35.23  E-value: 8.15e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17551128    47 NTITVREGKKLMVSCVFESDeqiHKSDLLWKQaNGNNIDGESNPSLFSVILNekgskhrkTSLHFSSVHTRDTGLYTCT 125
Cdd:pfam13927   9 SSVTVREGETVTLTCEATGS---PPPTITWYK-NGEPISSGSTRSRSLSGSN--------STLTISNVTRSDAGTYTCV 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH