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Conserved domains on  [gi|17570215|ref|NP_508959|]
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DM13 domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DM13 smart00686
Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis ...
 38-146 3.11e-40

Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9;


:

Pssm-ID: 128929  Cd Length: 108  Bit Score: 140.96  E-value: 3.11e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215     38 SSPETDISGQVFIVNATTLQIFNLTFSPSQQDLYFWLDTKDVPTREGIKAHTFEYG-ITPLGSFPedNDRVVVHVPEKHR 116
Cdd:smart00686   1 SLQHGVSSDPVEIVDAKTLRIPNFSYDGSGPDAYFWVGAGSRPDNEGGKKVPDEYGyCNPLRRYH--NEDIVLRLPESLT 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 17570215    117 IDEFKSFSIYSFKTDKSMASVVFPENVKIP 146
Cdd:smart00686  79 IDDIKWFSVWCLKTAHNFGHVLFPENLNIP 108
DM13 super family cl02735
Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system ...
 160-264 1.70e-24

Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system potentially involved in oxidative modification of animal cell-surface proteins. It contains a nearly absolutely conserved cysteine, which could be involved in a redox reaction, either as a naked thiol group or through binding a prosthetic group like heme.


The actual alignment was detected with superfamily member smart00686:

Pssm-ID: 470661  Cd Length: 108  Bit Score: 97.81  E-value: 1.70e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215    160 YQLRSGPLYVIDRRTIKVYGFTFEGNkAPKTYFYAGRGASVSYSSGVKVAirgkDEKEISEISENYRGgKDIILELPENY 239
Cdd:smart00686   4 HGVSSDPVEIVDAKTLRIPNFSYDGS-GPDAYFWVGAGSRPDNEGGKKVP----DEYGYCNPLRRYHN-EDIVLRLPESL 77

                           90       100
                   ....*....|....*....|....*
gi 17570215    240 DIFHIDWISVYCYKYRVNFGSVLVP 264
Cdd:smart00686  78 TIDDIKWFSVWCLKTAHNFGHVLFP 102
 
Name Accession Description Interval E-value
DM13 smart00686
Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis ...
 38-146 3.11e-40

Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9;


Pssm-ID: 128929  Cd Length: 108  Bit Score: 140.96  E-value: 3.11e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215     38 SSPETDISGQVFIVNATTLQIFNLTFSPSQQDLYFWLDTKDVPTREGIKAHTFEYG-ITPLGSFPedNDRVVVHVPEKHR 116
Cdd:smart00686   1 SLQHGVSSDPVEIVDAKTLRIPNFSYDGSGPDAYFWVGAGSRPDNEGGKKVPDEYGyCNPLRRYH--NEDIVLRLPESLT 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 17570215    117 IDEFKSFSIYSFKTDKSMASVVFPENVKIP 146
Cdd:smart00686  79 IDDIKWFSVWCLKTAHNFGHVLFPENLNIP 108
DM13 smart00686
Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis ...
 160-264 1.70e-24

Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9;


Pssm-ID: 128929  Cd Length: 108  Bit Score: 97.81  E-value: 1.70e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215    160 YQLRSGPLYVIDRRTIKVYGFTFEGNkAPKTYFYAGRGASVSYSSGVKVAirgkDEKEISEISENYRGgKDIILELPENY 239
Cdd:smart00686   4 HGVSSDPVEIVDAKTLRIPNFSYDGS-GPDAYFWVGAGSRPDNEGGKKVP----DEYGYCNPLRRYHN-EDIVLRLPESL 77

                           90       100
                   ....*....|....*....|....*
gi 17570215    240 DIFHIDWISVYCYKYRVNFGSVLVP 264
Cdd:smart00686  78 TIDDIKWFSVWCLKTAHNFGHVLFP 102
DM13 pfam10517
Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system ...
 154-261 1.41e-21

Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system potentially involved in oxidative modification of animal cell-surface proteins. It contains a nearly absolutely conserved cysteine, which could be involved in a redox reaction, either as a naked thiol group or through binding a prosthetic group like heme.


Pssm-ID: 463130  Cd Length: 105  Bit Score: 89.61  E-value: 1.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215   154 EFSGKRYQLrSGPLYVIDRRTIKVYGFTFEGNkAPKTYFYAGRGASVSYSSGVKvaIRGKDEKEISEIsENYRGGKDIIL 233
Cdd:pfam10517   1 EFVSGEHGT-SGTVYIVDDRTLELEGFATDGP-GPDLYVWLGDSPVPSGKDGFK--VPDEDGVTLGPL-KGYSGEQRYTL 75

                          90       100
                  ....*....|....*....|....*...
gi 17570215   234 ELPENYDIFHIDWISVYCYKYRVNFGSV 261
Cdd:pfam10517  76 TLPAGVDLADYKSVSIWCERFNVNFGAA 103
DM13 pfam10517
Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system ...
 36-139 1.07e-15

Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system potentially involved in oxidative modification of animal cell-surface proteins. It contains a nearly absolutely conserved cysteine, which could be involved in a redox reaction, either as a naked thiol group or through binding a prosthetic group like heme.


Pssm-ID: 463130  Cd Length: 105  Bit Score: 72.66  E-value: 1.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215    36 DLSSPETDISGQVFIVNATTLQIFNLTFSPSQQDLYFWLDTKDVPTREGIKAHTFEYGIT--PLGSFpEDNDRVVVHVPE 113
Cdd:pfam10517   1 EFVSGEHGTSGTVYIVDDRTLELEGFATDGPGPDLYVWLGDSPVPSGKDGFKVPDEDGVTlgPLKGY-SGEQRYTLTLPA 79

                          90       100
                  ....*....|....*....|....*.
gi 17570215   114 KHRIDEFKSFSIYSFKTDKSMASVVF 139
Cdd:pfam10517  80 GVDLADYKSVSIWCERFNVNFGAAPL 105
 
Name Accession Description Interval E-value
DM13 smart00686
Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis ...
 38-146 3.11e-40

Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9;


Pssm-ID: 128929  Cd Length: 108  Bit Score: 140.96  E-value: 3.11e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215     38 SSPETDISGQVFIVNATTLQIFNLTFSPSQQDLYFWLDTKDVPTREGIKAHTFEYG-ITPLGSFPedNDRVVVHVPEKHR 116
Cdd:smart00686   1 SLQHGVSSDPVEIVDAKTLRIPNFSYDGSGPDAYFWVGAGSRPDNEGGKKVPDEYGyCNPLRRYH--NEDIVLRLPESLT 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 17570215    117 IDEFKSFSIYSFKTDKSMASVVFPENVKIP 146
Cdd:smart00686  79 IDDIKWFSVWCLKTAHNFGHVLFPENLNIP 108
DM13 smart00686
Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis ...
 160-264 1.70e-24

Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9;


Pssm-ID: 128929  Cd Length: 108  Bit Score: 97.81  E-value: 1.70e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215    160 YQLRSGPLYVIDRRTIKVYGFTFEGNkAPKTYFYAGRGASVSYSSGVKVAirgkDEKEISEISENYRGgKDIILELPENY 239
Cdd:smart00686   4 HGVSSDPVEIVDAKTLRIPNFSYDGS-GPDAYFWVGAGSRPDNEGGKKVP----DEYGYCNPLRRYHN-EDIVLRLPESL 77

                           90       100
                   ....*....|....*....|....*
gi 17570215    240 DIFHIDWISVYCYKYRVNFGSVLVP 264
Cdd:smart00686  78 TIDDIKWFSVWCLKTAHNFGHVLFP 102
DM13 pfam10517
Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system ...
 154-261 1.41e-21

Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system potentially involved in oxidative modification of animal cell-surface proteins. It contains a nearly absolutely conserved cysteine, which could be involved in a redox reaction, either as a naked thiol group or through binding a prosthetic group like heme.


Pssm-ID: 463130  Cd Length: 105  Bit Score: 89.61  E-value: 1.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215   154 EFSGKRYQLrSGPLYVIDRRTIKVYGFTFEGNkAPKTYFYAGRGASVSYSSGVKvaIRGKDEKEISEIsENYRGGKDIIL 233
Cdd:pfam10517   1 EFVSGEHGT-SGTVYIVDDRTLELEGFATDGP-GPDLYVWLGDSPVPSGKDGFK--VPDEDGVTLGPL-KGYSGEQRYTL 75

                          90       100
                  ....*....|....*....|....*...
gi 17570215   234 ELPENYDIFHIDWISVYCYKYRVNFGSV 261
Cdd:pfam10517  76 TLPAGVDLADYKSVSIWCERFNVNFGAA 103
DM13 pfam10517
Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system ...
 36-139 1.07e-15

Electron transfer DM13; The DM13 domain is a component of a novel electron-transfer system potentially involved in oxidative modification of animal cell-surface proteins. It contains a nearly absolutely conserved cysteine, which could be involved in a redox reaction, either as a naked thiol group or through binding a prosthetic group like heme.


Pssm-ID: 463130  Cd Length: 105  Bit Score: 72.66  E-value: 1.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570215    36 DLSSPETDISGQVFIVNATTLQIFNLTFSPSQQDLYFWLDTKDVPTREGIKAHTFEYGIT--PLGSFpEDNDRVVVHVPE 113
Cdd:pfam10517   1 EFVSGEHGTSGTVYIVDDRTLELEGFATDGPGPDLYVWLGDSPVPSGKDGFKVPDEDGVTlgPLKGY-SGEQRYTLTLPA 79

                          90       100
                  ....*....|....*....|....*.
gi 17570215   114 KHRIDEFKSFSIYSFKTDKSMASVVF 139
Cdd:pfam10517  80 GVDLADYKSVSIWCERFNVNFGAAPL 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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