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Conserved domains on  [gi|25151529|ref|NP_508848|]
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Rootletin-like coiled-coil domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
195-430 3.90e-36

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 136.32  E-value: 3.90e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    195 RQRIDNNVEQQREYSEMMAALQNKVHEYRKHIAELEGRMVGarnrmlddptsnvmifDNYDPGNTYITNHNVELWSPARG 274
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLE----------------KTSELEKTELLLRKLTLEPRLQR 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    275 KREtilggggapglttvnvhagagysgsgvagygggvqamvgDPNANYE-MIARLDEERRRSDE-------YRMQWENER 346
Cdd:pfam15035   65 LER---------------------------------------EHSADLEeALIRLEEERQRSESlsqvnslLREQLEQAS 105

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    347 QKSLSLEDENDRLRREFERYANDSKDKEKTFINRERNLAQYLSDEQRKMLDLWTELQRVRKQFSDLKTHTEEDLDKQKAE 426
Cdd:pfam15035  106 RANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTE 185


                   ....
gi 25151529    427 FTRA 430
Cdd:pfam15035  186 FSRT 189
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 667-1595 4.79e-34

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 144.04  E-value: 4.79e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    667 EAERNSRRTDDKLR-----ASEAER------VAAEKARKFLE--DELAKLQASfqkSSTDDARKLRDEMDEhTNSIQEEF 733
Cdd:TIGR02168  176 ETERKLERTRENLDrlediLNELERqlksleRQAEKAERYKElkAELRELELA---LLVLRLEELREELEE-LQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    734 KTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYsddirrnIQKDLDDLREKYDRVHTD 813
Cdd:TIGR02168  252 EEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-------LRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    814 NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISD 893
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    894 YESQINLLRRHNDELDTTIKGHQGKIThlENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLEN 973
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    974 ELEKLRNENKELVGKEARARDaaNQQLSRANLLNKE-LEDTKQDLKHSTDVNKQLEQDIR-DLKERLANIgkggrISRDS 1051
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEG--FSEGVKALLKNQSgLSGILGVLSELISVDEGYEAAIEaALGGRLQAV-----VVENL 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1052 TTGTDGGAFgdrssvadpsRTRGAAGSTVFVPAaediESRGGGEIDiPSSGDVIHGRDGRDGRDAgnrgthTITNTKERI 1131
Cdd:TIGR02168  556 NAAKKAIAF----------LKQNELGRVTFLPL----DSIKGTEIQ-GNDREILKNIEGFLGVAK------DLVKFDPKL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1132 ERIEKNILDRYhddeLVEHKIREVNDRWKRELERLenekddlerRIRELEDEL----SQIGRGNDKTENDITELKR---K 1204
Cdd:TIGR02168  615 RKALSYLLGGV----LVVDDLDNALELAKKLRPGY---------RIVTLDGDLvrpgGVITGGSAKTNSSILERRReieE 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1205 HAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLY 1284
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKA-LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1285 GQNQKIKDEwddfRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHL 1364
Cdd:TIGR02168  761 AEIEELEER----LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1365 EDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDA 1444
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1445 LKELKNSLSHAKTEKERLQNafrektkqadhlnqlasQFDTKLTKLRNELQDTNDklitsdternalrnELQKLSQELKF 1524
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEV-----------------RIDNLQERLSEEYSLTLE--------------EAEALENKIED 965

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529   1525 GNEQIQRKSDEYQTTIDDLAhshRVSedsrLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSE 1595
Cdd:TIGR02168  966 DEEEARRRLKRLENKIKELG---PVN----LAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1239-2137 8.13e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 127.09  E-value: 8.13e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1239 ENLKSVED---DLRDKLNNLEKQlADSLNRENELEREKRDYDekINSLYGQNQKIKDEWDDFRNDADKEIQKWKTdaytV 1315
Cdd:TIGR02168  186 ENLDRLEDilnELERQLKSLERQ-AEKAERYKELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEE----L 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNR------- 1388
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKldelaee 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1389 LRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQnafRE 1468
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1469 KTKQADHLNQLASQFDtkltklRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHShr 1548
Cdd:TIGR02168  416 RERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL-- 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1549 vseDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQ---DYIKADSE---------RDILSDALRRFQSSANRVINF 1616
Cdd:TIGR02168  488 ---QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlsELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1617 HTFVDGGAGYV---DGVPGGTSVIGGGPSAQRS-GAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSD-VAYPRS 1691
Cdd:TIGR02168  565 LKQNELGRVTFlplDSIKGTEIQGNDREILKNIeGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELaKKLRPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1692 VPFPpSADFSSGRPGAASAGGRvinnlDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETH 1771
Cdd:TIGR02168  645 YRIV-TLDGDLVRPGGVITGGS-----AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1772 TTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQL 1851
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1852 KNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDM 1931
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1932 KDDTDKLRRDLTKAESVENELRKTIDiqsKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRdykqrvhdv 2011
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELR---ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--------- 946

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2012 nnrvSELQRQLQDANTEKNRVEDRFLSVEKVVntmrtteTDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNssql 2091
Cdd:TIGR02168  947 ----EEYSLTLEEAEALENKIEDDEEEARRRL-------KRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKED---- 1011

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 25151529   2092 sdgwkkekitLLKKIELLENEKRRTDAAIRETALQR-EAIEKSLNAM 2137
Cdd:TIGR02168 1012 ----------LTEAKETLEEAIEEIDREARERFKDTfDQVNENFQRV 1048
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 522-797 4.35e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    522 EESIERNIeLESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRtrslspgktplppsea 601
Cdd:TIGR02169  781 LNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI---------------- 843

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    602 lravrntfrnkDNDIQQLERKLKIAESQVK--EFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERnsrrtddKL 679
Cdd:TIGR02169  844 -----------DLKEQIKSIEKEIENLNGKkeELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER-------KI 905

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    680 RASEAERvaaEKARKFLEDELAKLQASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSE-- 757
Cdd:TIGR02169  906 EELEAQI---EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEye 982

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529    758 -----VNPLKDKYRDLENEYNSTQRRIEEKETQIRYS-----DDIRRNIQ 797
Cdd:TIGR02169  983 evlkrLDELKEKRAKLEEERKAILERIEEYEKKKREVfmeafEAINENFN 1032
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1971-2357 3.78e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


:

Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTE----KNRVEDRFLSVEKVVNTM 2046
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaeaEAEIEERREELGERARAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2047 RTTETDLR--QQLETAKNekrvatkeLEDLKRRLAQLenerrnsSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETA 2124
Cdd:COG3883   96 YRSGGSVSylDVLLGSES--------FSDFLDRLSAL-------SKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2125 LQREAIEKSLNAMERENKELykncaqlqqqiaqlemengNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRN 2204
Cdd:COG3883  161 ALKAELEAAKAELEAQQAEQ-------------------EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2205 RIKQLEDQIAILRDQLDGERRRRREYVDRSMVNDIGRLGSNVLGIRNSYGDNSIDAIINGGSRSVGFYPRSTFASNPLTP 2284
Cdd:COG3883  222 AAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASG 301

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2285 PLGSSTPTHRPHVTDFRSAVDAGSSYRRPISTIEDSGSVYGGSIRDRDSVYGGGGRDSSFGTRAGDSISRAGV 2357
Cdd:COG3883  302 GSGGGSGGAGGVGSGGGAGAVVGGASAGGGGGSGGGGGSSGGGSGGGGGGGGGGGGSSSGGGGGGVGLSVGGG 374
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
195-430 3.90e-36

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 136.32  E-value: 3.90e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    195 RQRIDNNVEQQREYSEMMAALQNKVHEYRKHIAELEGRMVGarnrmlddptsnvmifDNYDPGNTYITNHNVELWSPARG 274
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLE----------------KTSELEKTELLLRKLTLEPRLQR 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    275 KREtilggggapglttvnvhagagysgsgvagygggvqamvgDPNANYE-MIARLDEERRRSDE-------YRMQWENER 346
Cdd:pfam15035   65 LER---------------------------------------EHSADLEeALIRLEEERQRSESlsqvnslLREQLEQAS 105

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    347 QKSLSLEDENDRLRREFERYANDSKDKEKTFINRERNLAQYLSDEQRKMLDLWTELQRVRKQFSDLKTHTEEDLDKQKAE 426
Cdd:pfam15035  106 RANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTE 185


                   ....
gi 25151529    427 FTRA 430
Cdd:pfam15035  186 FSRT 189
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 667-1595 4.79e-34

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 144.04  E-value: 4.79e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    667 EAERNSRRTDDKLR-----ASEAER------VAAEKARKFLE--DELAKLQASfqkSSTDDARKLRDEMDEhTNSIQEEF 733
Cdd:TIGR02168  176 ETERKLERTRENLDrlediLNELERqlksleRQAEKAERYKElkAELRELELA---LLVLRLEELREELEE-LQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    734 KTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYsddirrnIQKDLDDLREKYDRVHTD 813
Cdd:TIGR02168  252 EEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-------LRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    814 NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISD 893
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    894 YESQINLLRRHNDELDTTIKGHQGKIThlENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLEN 973
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    974 ELEKLRNENKELVGKEARARDaaNQQLSRANLLNKE-LEDTKQDLKHSTDVNKQLEQDIR-DLKERLANIgkggrISRDS 1051
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEG--FSEGVKALLKNQSgLSGILGVLSELISVDEGYEAAIEaALGGRLQAV-----VVENL 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1052 TTGTDGGAFgdrssvadpsRTRGAAGSTVFVPAaediESRGGGEIDiPSSGDVIHGRDGRDGRDAgnrgthTITNTKERI 1131
Cdd:TIGR02168  556 NAAKKAIAF----------LKQNELGRVTFLPL----DSIKGTEIQ-GNDREILKNIEGFLGVAK------DLVKFDPKL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1132 ERIEKNILDRYhddeLVEHKIREVNDRWKRELERLenekddlerRIRELEDEL----SQIGRGNDKTENDITELKR---K 1204
Cdd:TIGR02168  615 RKALSYLLGGV----LVVDDLDNALELAKKLRPGY---------RIVTLDGDLvrpgGVITGGSAKTNSSILERRReieE 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1205 HAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLY 1284
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKA-LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1285 GQNQKIKDEwddfRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHL 1364
Cdd:TIGR02168  761 AEIEELEER----LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1365 EDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDA 1444
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1445 LKELKNSLSHAKTEKERLQNafrektkqadhlnqlasQFDTKLTKLRNELQDTNDklitsdternalrnELQKLSQELKF 1524
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEV-----------------RIDNLQERLSEEYSLTLE--------------EAEALENKIED 965

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529   1525 GNEQIQRKSDEYQTTIDDLAhshRVSedsrLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSE 1595
Cdd:TIGR02168  966 DEEEARRRLKRLENKIKELG---PVN----LAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1239-2137 8.13e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 127.09  E-value: 8.13e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1239 ENLKSVED---DLRDKLNNLEKQlADSLNRENELEREKRDYDekINSLYGQNQKIKDEWDDFRNDADKEIQKWKTdaytV 1315
Cdd:TIGR02168  186 ENLDRLEDilnELERQLKSLERQ-AEKAERYKELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEE----L 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNR------- 1388
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKldelaee 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1389 LRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQnafRE 1468
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1469 KTKQADHLNQLASQFDtkltklRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHShr 1548
Cdd:TIGR02168  416 RERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL-- 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1549 vseDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQ---DYIKADSE---------RDILSDALRRFQSSANRVINF 1616
Cdd:TIGR02168  488 ---QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlsELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1617 HTFVDGGAGYV---DGVPGGTSVIGGGPSAQRS-GAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSD-VAYPRS 1691
Cdd:TIGR02168  565 LKQNELGRVTFlplDSIKGTEIQGNDREILKNIeGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELaKKLRPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1692 VPFPpSADFSSGRPGAASAGGRvinnlDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETH 1771
Cdd:TIGR02168  645 YRIV-TLDGDLVRPGGVITGGS-----AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1772 TTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQL 1851
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1852 KNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDM 1931
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1932 KDDTDKLRRDLTKAESVENELRKTIDiqsKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRdykqrvhdv 2011
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELR---ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--------- 946

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2012 nnrvSELQRQLQDANTEKNRVEDRFLSVEKVVntmrtteTDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNssql 2091
Cdd:TIGR02168  947 ----EEYSLTLEEAEALENKIEDDEEEARRRL-------KRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKED---- 1011

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 25151529   2092 sdgwkkekitLLKKIELLENEKRRTDAAIRETALQR-EAIEKSLNAM 2137
Cdd:TIGR02168 1012 ----------LTEAKETLEEAIEEIDREARERFKDTfDQVNENFQRV 1048
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1731-2221 1.69e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1811 SQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRtdldnahtdiRSLRDKEEQWDSSRFQLETKMRESD 1890
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE----------AELAEAEEELEELAEELLEALRAAA 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1891 SDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLK 1970
Cdd:COG1196  397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNR--VSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRT 2048
Cdd:COG1196  477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2049 TETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRnssqlsdgwkkekITLLKKIELLENEKRrtDAAIRETALQRE 2128
Cdd:COG1196  557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR-------------GAIGAAVDLVASDLR--EADARYYVLGDT 621

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2129 AIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQ 2208
Cdd:COG1196  622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                        490
                 ....*....|...
gi 25151529 2209 LEDQIAILRDQLD 2221
Cdd:COG1196  702 EEEEERELAEAEE 714
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 689-1275 1.84e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  689 AEKARKF--LEDELAKLQASfqksstddARKLRDEmdeHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYR 766
Cdd:COG1196  209 AEKAERYreLKEELKELEAE--------LLLLKLR---ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  767 DLENEYNSTQRRIEEKETQIRysddirrNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQ 846
Cdd:COG1196  278 ELELELEEAQAEEYELLAELA-------RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  847 KQKDEHARHLFDIRHKLETEIKGRQDLEkngarnnDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENEL 926
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAE-------EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  927 HSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLL 1006
Cdd:COG1196  424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1007 NKELEDTKQDLKHS-----------------------------------TDVNKQLEQDIRDLKER---------LANIG 1042
Cdd:COG1196  504 EGFLEGVKAALLLAglrglagavavligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAkagratflpLDKIR 583

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1043 KGGRISRDSTTGTDGGAFGDRSS--VADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRG 1120
Cdd:COG1196  584 ARAALAAALARGAIGAAVDLVASdlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1121 THTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTEN---D 1197
Cdd:COG1196  664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEellE 743

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1198 ITELKRKHAAEIDKLKSDISALhDKHLSDLDDEKEQYGK----AVENLKSVE---DDLRDKLNNLEKQLADSLNRENELE 1270
Cdd:COG1196  744 EEELLEEEALEELPEPPDLEEL-ERELERLEREIEALGPvnllAIEEYEELEeryDFLSEQREDLEEARETLEEAIEEID 822


                 ....*
gi 25151529 1271 REKRD 1275
Cdd:COG1196  823 RETRE 827
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 896-1613 1.16e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 80.55  E-value: 1.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 SQINLLRRHNDELDTTIK--GHQGKiTHLENELHSRSGEIEklnDLNQRLQKEKQdiLNQKLKLdgdvqALKETIRKLEN 973
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKiiAYPGK-EHIERVLEEYSHQVK---DLQRRLNESNE--LHEKQKF-----YLRQSVIDLQT 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    974 ELEKLRNENKELVgkEARARDAANQQLSRANLLNK--ELEDT---KQDLKHstDVNKQLEQDIRDLKERLANIGKGGRIS 1048
Cdd:pfam15921  118 KLQEMQMERDAMA--DIRRRESQSQEDLRNQLQNTvhELEAAkclKEDMLE--DSNTQIEQLRKMMLSHEGVLQEIRSIL 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1049 RDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGrdgrdgrDAGNRGTHTITNTK 1128
Cdd:pfam15921  194 VDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKS-------ESQNKIELLLQQHQ 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1129 ERIERI----EKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIgrgndktENDITELKRK 1204
Cdd:pfam15921  267 DRIEQLisehEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQL-------RSELREAKRM 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1205 HAAEIDKLKSDIsALHDKHLSDLDDEKEQYGKAVENLksveDDlrdklnNLEKQLADSLNRENELEREKRdydekinsly 1284
Cdd:pfam15921  340 YEDKIEELEKQL-VLANSELTEARTERDQFSQESGNL----DD------QLQKLLADLHKREKELSLEKE---------- 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1285 gQNQKIkdeWD-DFRNDADKEIQKWKTDAYTVrsEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRH 1363
Cdd:pfam15921  399 -QNKRL---WDrDTGNSITIDHLRRELDDRNM--EVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLES 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1364 LEDELADTKGNLVQKEMDLESTQnrlRSLEDQHSTLQ----------SDANKWRGELDAALRENDILKSNN---TNMETD 1430
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESSE---RTVSDLTASLQekeraieatnAEITKLRSRVDLKLQELQHLKNEGdhlRNVQTE 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1431 LTRLKNRLKSAEDALKELKNSL--------SHAKT------EKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQD 1496
Cdd:pfam15921  550 CEALKLQMAEKDKVIEILRQQIenmtqlvgQHGRTagamqvEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSD 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1497 ---TNDKLITSDTER------------------NALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSE---D 1552
Cdd:pfam15921  630 lelEKVKLVNAGSERlravkdikqerdqllnevKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQselE 709

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   1553 SRLNALQELE------------------ARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRV 1613
Cdd:pfam15921  710 QTRNTLKSMEgsdghamkvamgmqkqitAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
520-1043 1.44e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 80.11  E-value: 1.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   520 KYEESIERNI-ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKnvdgtvSIKRTRSLspgktplpp 598
Cdd:PRK03918  186 KRTENIEELIkEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE------LEKELESL--------- 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   599 SEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEfLNKFENADEARRRLDK---QFADAKREISNLQKSVDEAERNSRRT 675
Cdd:PRK03918  251 EGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEER 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   676 DDKLRASEAERVAAEKARKFLEDELAKLQASFQKssTDDARKLRDEMDEH----TNSIQEEFKTRIDELNRRVENLLREN 751
Cdd:PRK03918  330 IKELEEKEERLEELKKKLKELEKRLEELEERHEL--YEEAKAKKEELERLkkrlTGLTPEKLEKELEELEKAKEEIEEEI 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   752 NRLKSEVNPLKDKYRDLE---NEYNSTQRRI----------EEKETQIRYSDDIRR--NIQKDLDDLREKYDRVHTDNEK 816
Cdd:PRK03918  408 SKITARIGELKKEIKELKkaiEELKKAKGKCpvcgrelteeHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELEK 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   817 ILGELEHAQKAAHLAEqQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQdlekngARNNDELDKLRQTISDYES 896
Cdd:PRK03918  488 VLKKESELIKLKELAE-QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI------KSLKKELEKLEELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   897 QINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRL---QKEKQDILNQKLKLDGDVQALKETIRKLEN 973
Cdd:PRK03918  561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELkdaEKELEREEKELKKLEEELDKAFEELAETEK 640

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529   974 ELEKLRNENKELVGK--EARARDAANQQLSranlLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:PRK03918  641 RLEELRKELEELEKKysEEEYEELREEYLE----LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1740-2144 4.67e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.99  E-value: 4.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1740 QSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQR 1819
Cdd:PRK02224  310 EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1820 DEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQwdSSRFQLETKMRESDSD------- 1892
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE--AEALLEAGKCPECGQPvegsphv 467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1893 --TNKYQLQIASFESERQILTEKIKELDGALrlsdSKVQDMKDDTDKLRRDLTKAESVEnelrKTIDIQSKTSHEYQLLK 1970
Cdd:PRK02224  468 etIEEDRERVEELEAELEDLEEEVEEVEERL----ERAEDLVEAEDRIERLEERREDLE----ELIAERRETIEEKRERA 539

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1971 DQLlntqnelngaNNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDrflsvekvVNTMRTTE 2050
Cdd:PRK02224  540 EEL----------RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAI 601

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2051 TDLRQQLETaKNEKRVATKELEDLKRRLAQLENERRnsSQLSDGWKKEKITLLK-KIELLENEKRRTDAAIRETALQREA 2129
Cdd:PRK02224  602 ADAEDEIER-LREKREALAELNDERRERLAEKRERK--RELEAEFDEARIEEAReDKERAEEYLEQVEEKLDELREERDD 678

                         410
                  ....*....|....*
gi 25151529  2130 IEKSLNAMERENKEL 2144
Cdd:PRK02224  679 LQAEIGAVENELEEL 693
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1732-2193 2.74e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.35  E-value: 2.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1732 IANLEGTLQSLLNKIEK----LEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKT 1807
Cdd:pfam05483  224 IQHLEEEYKKEINDKEKqvslLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKM 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1808 LLRSQEEALKQRdEERRQMKSKMVAAELQArgKEAQLRHLNE----------QLKNLRTDLDN-AHTDIRSLRDKEEQWD 1876
Cdd:pfam05483  304 SLQRSMSTQKAL-EEDLQIATKTICQLTEE--KEAQMEELNKakaahsfvvtEFEATTCSLEElLRTEQQRLEKNEDQLK 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1877 SSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDgalrlSDSKVQDMKDDTDKLRRDLTKAESVENELRKTI 1956
Cdd:pfam05483  381 IITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD-----EKKQFEKIAEELKGKEQELIFLLQAREKEIHDL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1957 DIQ---SKTSHEYQLLKDQLLNTQNElngannrKQQLENELLNVRSE--VRDYKQRVHDVNNRVSELQRQLQDANTEKNR 2031
Cdd:pfam05483  456 EIQltaIKTSEEHYLKEVEDLKTELE-------KEKLKNIELTAHCDklLLENKELTQEASDMTLELKKHQEDIINCKKQ 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2032 vEDRFLsveKVVNTMRTTETDLRQQLETAKNEKRvatKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLEN 2111
Cdd:pfam05483  529 -EERML---KQIENLEEKEMNLRDELESVREEFI---QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2112 EKRRTDAAIRETALQREAIEKSLNAmerENKELykNCAQLQQQIAQLEMENG-NRILELTNKQREEQERQLIRMRQEKGQ 2190
Cdd:pfam05483  602 QIENKNKNIEELHQENKALKKKGSA---ENKQL--NAYEIKVNKLELELASAkQKFEEIIDNYQKEIEDKKISEEKLLEE 676


                   ...
gi 25151529   2191 IEK 2193
Cdd:pfam05483  677 VEK 679
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 522-797 4.35e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    522 EESIERNIeLESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRtrslspgktplppsea 601
Cdd:TIGR02169  781 LNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI---------------- 843

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    602 lravrntfrnkDNDIQQLERKLKIAESQVK--EFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERnsrrtddKL 679
Cdd:TIGR02169  844 -----------DLKEQIKSIEKEIENLNGKkeELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER-------KI 905

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    680 RASEAERvaaEKARKFLEDELAKLQASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSE-- 757
Cdd:TIGR02169  906 EELEAQI---EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEye 982

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529    758 -----VNPLKDKYRDLENEYNSTQRRIEEKETQIRYS-----DDIRRNIQ 797
Cdd:TIGR02169  983 evlkrLDELKEKRAKLEEERKAILERIEEYEKKKREVfmeafEAINENFN 1032
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 530-688 6.37e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 6.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  530 ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDgTVSIKRTRSlspgktplppSEALRAVRNT- 608
Cdd:COG1579   21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIE-EVEARIKKY----------EEQLGNVRNNk 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  609 -FRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERV 687
Cdd:COG1579   90 eYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169


                 .
gi 25151529  688 A 688
Cdd:COG1579  170 A 170
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 515-775 2.48e-04

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 45.02  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    515 KELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEknvdgtvsikrtrslspgkt 594
Cdd:pfam00261   18 KEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKLEEAEKAADESE-------------------- 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    595 plppsEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFEnadEARRRLdkqfadakreisnlqksvDEAERNSRR 674
Cdd:pfam00261   78 -----RGRKVLENRALKDEEKMEILEAQLKEAKEIAEEADRKYE---EVARKL------------------VVVEGDLER 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    675 TDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSStddarKLRDEMDEHTNSIQEEFK---TRIDELNRRVENLLREN 751
Cdd:pfam00261  132 AEERAELAESKIVELEEELKVVGNNLKSLEASEEKAS-----EREDKYEEQIRFLTEKLKeaeTRAEFAERSVQKLEKEV 206

                          250       260
                   ....*....|....*....|....
gi 25151529    752 NRLKSEVNPLKDKYRDLENEYNST 775
Cdd:pfam00261  207 DRLEDELEAEKEKYKAISEELDQT 230
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1971-2357 3.78e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTE----KNRVEDRFLSVEKVVNTM 2046
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaeaEAEIEERREELGERARAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2047 RTTETDLR--QQLETAKNekrvatkeLEDLKRRLAQLenerrnsSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETA 2124
Cdd:COG3883   96 YRSGGSVSylDVLLGSES--------FSDFLDRLSAL-------SKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2125 LQREAIEKSLNAMERENKELykncaqlqqqiaqlemengNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRN 2204
Cdd:COG3883  161 ALKAELEAAKAELEAQQAEQ-------------------EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2205 RIKQLEDQIAILRDQLDGERRRRREYVDRSMVNDIGRLGSNVLGIRNSYGDNSIDAIINGGSRSVGFYPRSTFASNPLTP 2284
Cdd:COG3883  222 AAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASG 301

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2285 PLGSSTPTHRPHVTDFRSAVDAGSSYRRPISTIEDSGSVYGGSIRDRDSVYGGGGRDSSFGTRAGDSISRAGV 2357
Cdd:COG3883  302 GSGGGSGGAGGVGSGGGAGAVVGGASAGGGGGSGGGGGSSGGGSGGGGGGGGGGGGSSSGGGGGGVGLSVGGG 374
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 855-991 1.20e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.47  E-value: 1.20e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529     855 HLFDIRHKLETEIKG----RQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDttiKGHQGKITHLENELHSRS 930
Cdd:smart00787  141 LLEGLKEGLDENLEGlkedYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELE---DCDPTELDRAKEKLKKLL 217

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529     931 GEIE----KLNDLNQRLQKEKQDIlnqklkldGDVQALKETIRKLENELEKLRNENKELVGKEAR 991
Cdd:smart00787  218 QEIMikvkKLEELEEELQELESKI--------EDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIE 274
PRK12704 PRK12704
phosphodiesterase; Provisional
 609-706 3.11e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 3.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   609 FRNKDNDIQQLERKLKIAESQVKeflNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLraseaERVA 688
Cdd:PRK12704   77 LRERRNELQKLEKRLLQKEENLD---RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL-----ERIS 148

                          90       100
                  ....*....|....*....|....
gi 25151529   689 ---AEKARKFLEDEL---AKLQAS 706
Cdd:PRK12704  149 gltAEEAKEILLEKVeeeARHEAA 172
ClyA_Cry6Aa-like cd22656
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ...
 718-913 9.99e-03

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.


Pssm-ID: 439154 [Multi-domain]  Cd Length: 309  Bit Score: 40.43  E-value: 9.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  718 LRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQI--RYSDDIRRN 795
Cdd:cd22656   97 LELIDDLADATDDEELEEAKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALkdLLTDEGGAI 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  796 IQKDLDDLREKYDRVHTD-NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDeharHLFDIRHKLETEIKGRQDLE 874
Cdd:cd22656  177 ARKEIKDLQKELEKLNEEyAAKLKAKIDELKALIADDEAKLAAALRLIADLTAADT----DLDNLLALIGPAIPALEKLQ 252

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 25151529  875 KNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIK 913
Cdd:cd22656  253 GAWQAIATDLDSLKDLLEDDISKIPAAILAKLELEKAIE 291
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
195-430 3.90e-36

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 136.32  E-value: 3.90e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    195 RQRIDNNVEQQREYSEMMAALQNKVHEYRKHIAELEGRMVGarnrmlddptsnvmifDNYDPGNTYITNHNVELWSPARG 274
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLE----------------KTSELEKTELLLRKLTLEPRLQR 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    275 KREtilggggapglttvnvhagagysgsgvagygggvqamvgDPNANYE-MIARLDEERRRSDE-------YRMQWENER 346
Cdd:pfam15035   65 LER---------------------------------------EHSADLEeALIRLEEERQRSESlsqvnslLREQLEQAS 105

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    347 QKSLSLEDENDRLRREFERYANDSKDKEKTFINRERNLAQYLSDEQRKMLDLWTELQRVRKQFSDLKTHTEEDLDKQKAE 426
Cdd:pfam15035  106 RANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTE 185


                   ....
gi 25151529    427 FTRA 430
Cdd:pfam15035  186 FSRT 189
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 667-1595 4.79e-34

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 144.04  E-value: 4.79e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    667 EAERNSRRTDDKLR-----ASEAER------VAAEKARKFLE--DELAKLQASfqkSSTDDARKLRDEMDEhTNSIQEEF 733
Cdd:TIGR02168  176 ETERKLERTRENLDrlediLNELERqlksleRQAEKAERYKElkAELRELELA---LLVLRLEELREELEE-LQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    734 KTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYsddirrnIQKDLDDLREKYDRVHTD 813
Cdd:TIGR02168  252 EEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-------LRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    814 NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISD 893
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    894 YESQINLLRRHNDELDTTIKGHQGKIThlENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLEN 973
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    974 ELEKLRNENKELVGKEARARDaaNQQLSRANLLNKE-LEDTKQDLKHSTDVNKQLEQDIR-DLKERLANIgkggrISRDS 1051
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEG--FSEGVKALLKNQSgLSGILGVLSELISVDEGYEAAIEaALGGRLQAV-----VVENL 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1052 TTGTDGGAFgdrssvadpsRTRGAAGSTVFVPAaediESRGGGEIDiPSSGDVIHGRDGRDGRDAgnrgthTITNTKERI 1131
Cdd:TIGR02168  556 NAAKKAIAF----------LKQNELGRVTFLPL----DSIKGTEIQ-GNDREILKNIEGFLGVAK------DLVKFDPKL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1132 ERIEKNILDRYhddeLVEHKIREVNDRWKRELERLenekddlerRIRELEDEL----SQIGRGNDKTENDITELKR---K 1204
Cdd:TIGR02168  615 RKALSYLLGGV----LVVDDLDNALELAKKLRPGY---------RIVTLDGDLvrpgGVITGGSAKTNSSILERRReieE 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1205 HAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLY 1284
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKA-LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1285 GQNQKIKDEwddfRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHL 1364
Cdd:TIGR02168  761 AEIEELEER----LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1365 EDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDA 1444
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1445 LKELKNSLSHAKTEKERLQNafrektkqadhlnqlasQFDTKLTKLRNELQDTNDklitsdternalrnELQKLSQELKF 1524
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEV-----------------RIDNLQERLSEEYSLTLE--------------EAEALENKIED 965

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529   1525 GNEQIQRKSDEYQTTIDDLAhshRVSedsrLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSE 1595
Cdd:TIGR02168  966 DEEEARRRLKRLENKIKELG---PVN----LAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1239-2137 8.13e-29

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 127.09  E-value: 8.13e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1239 ENLKSVED---DLRDKLNNLEKQlADSLNRENELEREKRDYDekINSLYGQNQKIKDEWDDFRNDADKEIQKWKTdaytV 1315
Cdd:TIGR02168  186 ENLDRLEDilnELERQLKSLERQ-AEKAERYKELKAELRELE--LALLVLRLEELREELEELQEELKEAEEELEE----L 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNR------- 1388
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKldelaee 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1389 LRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQnafRE 1468
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1469 KTKQADHLNQLASQFDtkltklRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHShr 1548
Cdd:TIGR02168  416 RERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL-- 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1549 vseDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQ---DYIKADSE---------RDILSDALRRFQSSANRVINF 1616
Cdd:TIGR02168  488 ---QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlsELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAF 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1617 HTFVDGGAGYV---DGVPGGTSVIGGGPSAQRS-GAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSD-VAYPRS 1691
Cdd:TIGR02168  565 LKQNELGRVTFlplDSIKGTEIQGNDREILKNIeGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELaKKLRPG 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1692 VPFPpSADFSSGRPGAASAGGRvinnlDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETH 1771
Cdd:TIGR02168  645 YRIV-TLDGDLVRPGGVITGGS-----AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1772 TTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQL 1851
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1852 KNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDM 1931
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1932 KDDTDKLRRDLTKAESVENELRKTIDiqsKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRdykqrvhdv 2011
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELR---ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--------- 946

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2012 nnrvSELQRQLQDANTEKNRVEDRFLSVEKVVntmrtteTDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNssql 2091
Cdd:TIGR02168  947 ----EEYSLTLEEAEALENKIEDDEEEARRRL-------KRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKED---- 1011

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 25151529   2092 sdgwkkekitLLKKIELLENEKRRTDAAIRETALQR-EAIEKSLNAM 2137
Cdd:TIGR02168 1012 ----------LTEAKETLEEAIEEIDREARERFKDTfDQVNENFQRV 1048
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1176-2116 2.69e-25

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 115.55  E-value: 2.69e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1176 RIRELEDELSQIGRG----NDKTENDITELKRKHAAEIDKLKSDIS--ALHDKHLSDLDDEKEQYGKAVENLKSVEDDLR 1249
Cdd:TIGR02169  118 RLSEIHDFLAAAGIYpegyNVVLQGDVTDFISMSPVERRKIIDEIAgvAEFDRKKEKALEELEEVEENIERLDLIIDEKR 197

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1250 DKLNNLEKQLADSLnRENELEREKRDYDEKINSlygqnqkikdewddfrndadKEIQKWKTDAYTVRSEAKALETTNTAL 1329
Cdd:TIGR02169  198 QQLERLRREREKAE-RYQALLKEKREYEGYELL--------------------KEKEALERQKEAIERQLASLEEELEKL 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1330 KAQLQAANDRIDHLTKTVNDHTSKVRDLTS--------QVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQS 1401
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlrvkeKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1402 DANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLAS 1481
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1482 QFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELkfgnEQIQRKSDEYQttiddlahshrvsedsrlnalQEL 1561
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYE---------------------QEL 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1562 EARKYEINDLtsrldstEQRLATLQQDYIKADSERDILSDALRRFqSSANRVINfhtfvdggagyvDGVPG--GTSVIGG 1639
Cdd:TIGR02169  472 YDLKEEYDRV-------EKELSKLQRELAEAEAQARASEERVRGG-RAVEEVLK------------ASIQGvhGTVAQLG 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1640 GPSAQRSGAYDPSSGGVIG----SGISGGPGGSDFGREIEIGRGD--------SDQSDVAYPRS----------VPFPPS 1697
Cdd:TIGR02169  532 SVGERYATAIEVAAGNRLNnvvvEDDAVAKEAIELLKRRKAGRATflplnkmrDERRDLSILSEdgvigfavdlVEFDPK 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1698 ---------------ADFSSGRPgaaSAGGRVINNLDG---TTTVNMNGGFDI--------ANLEGTLQSLLNKIEKLEM 1751
Cdd:TIGR02169  612 yepafkyvfgdtlvvEDIEAARR---LMGKYRMVTLEGelfEKSGAMTGGSRAprggilfsRSEPAELQRLRERLEGLKR 688

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1752 ERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALkqrdEERRQMKSKmV 1831
Cdd:TIGR02169  689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI----ENVKSELKE-L 763

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1832 AAELQArgKEAQLRHLNEQLKNLRTDLdnAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILT 1911
Cdd:TIGR02169  764 EARIEE--LEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ 839

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1912 EKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKtidiqsktshEYQLLKDQLLNTQNELNGANNRKQQLE 1991
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES----------RLGDLKKERDELEAQLRELERKIEELE 909

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1992 NELLNVRSEVRDYKQRVHDVNNRVSELQrqlqDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQqLETAKNEkrvATKEL 2071
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIE----DPKGEDEEIPEEELSLEDVQAELQRVEEEIRA-LEPVNML---AIQEY 981

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....*
gi 25151529   2072 EDLKRRLAQLENERrnssqlsDGWKKEKITLLKKIELLENEKRRT 2116
Cdd:TIGR02169  982 EEVLKRLDELKEKR-------AKLEEERKAILERIEEYEKKKREV 1019
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 648-1428 3.38e-24

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 111.70  E-value: 3.38e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    648 DKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKfLEDELAKLQASFQKSSTDDARKLRDEMDEHTN 727
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA-LLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    728 SIQEE---FKTRIDELNRRVENLLRENNRLKSEVNPLKdkyrdlENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLR 804
Cdd:TIGR02169  248 SLEEElekLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    805 EKYDRVHTDNEKILGELEHAQKAahLAEQQLKEIKIQrDDYQKQKDEharhlfdiRHKLETEIkgrQDLEKNGARNNDEL 884
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELERE--IEEERKRRDKLT-EEYAELKEE--------LEDLRAEL---EEVDKEFAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    885 DKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKE-------KQDILNQKLKL 957
Cdd:TIGR02169  388 KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEikkqewkLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    958 DGDVQALKETIRKLENELEKLRnenKELVGKEARARDAANQQLSRA---NLLNKELEDT--------KQDLKHSTDV--- 1023
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQ---RELAEAEAQARASEERVRGGRaveEVLKASIQGVhgtvaqlgSVGERYATAIeva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1024 ------NKQLEQD------IRDLKERlanigKGGRIS-----------RDSTTGTDGGAFGDRSSVADPSRTRGAA---- 1076
Cdd:TIGR02169  545 agnrlnNVVVEDDavakeaIELLKRR-----KAGRATflplnkmrderRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyv 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1077 -GSTVFVpaaEDIES--RGGGEI-------DIPSSGDVIHGrdgrdGRDAGNRGTHTITNTKERIERieknildryhdde 1146
Cdd:TIGR02169  620 fGDTLVV---EDIEAarRLMGKYrmvtlegELFEKSGAMTG-----GSRAPRGGILFSRSEPAELQR------------- 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1147 lVEHKIREVndrwKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHAA---EIDKLKSDISALHDKh 1223
Cdd:TIGR02169  679 -LRERLEGL----KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQE- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1224 LSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSlnRENELEREKRDYDEKINslygqnqkikdEWDDFRNDADK 1303
Cdd:TIGR02169  753 IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVS-----------RIEARLREIEQ 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1304 EIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLE 1383
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 25151529   1384 STQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNME 1428
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1160-2044 6.06e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.92  E-value: 6.06e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1160 KRELE-RLENEKDDLERrireLEDELSQIGRGNDKTEnditeLKRKHAAEIDKLKSDISALHdkhLSDLDDEKEQYGKAV 1238
Cdd:TIGR02168  174 RKETErKLERTRENLDR----LEDILNELERQLKSLE-----RQAEKAERYKELKAELRELE---LALLVLRLEELREEL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1239 ENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINS----LYGQNQKIKD------EWDDFRNDADKEIQKW 1308
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkeLYALANEISRleqqkqILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1309 KTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNR 1388
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1389 LRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMEtdLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFRE 1468
Cdd:TIGR02168  402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE--LEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1469 KTKQadhLNQLASQFDTkLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNeqiqrksdEYQTTID-DLAhsh 1547
Cdd:TIGR02168  480 AERE---LAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE--------GYEAAIEaALG--- 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1548 rvsedSRLNAL--QELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTFVDGGag 1625
Cdd:TIGR02168  545 -----GRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA-- 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1626 yVDGVPGGTSVIGGGPSAQR-SGAYDPSsggvigsgisggpggsdfgreieiGRGDSDQSDVAYPRSVPFPPSADFSSGR 1704
Cdd:TIGR02168  618 -LSYLLGGVLVVDDLDNALElAKKLRPG------------------------YRIVTLDGDLVRPGGVITGGSAKTNSSI 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1705 PGAASAGGRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNI 1784
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1785 EDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTD 1864
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1865 I----RSLRDKEEQWD----------SSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQD 1930
Cdd:TIGR02168  833 IaateRRLEDLEEQIEelsedieslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1931 MKDDTDKLRRDLTKAESVENELRKTID-IQSKTSHEYQLLKDQLLNTQN----ELNGANNRKQQLENEL-------LNVR 1998
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEAEALENkiedDEEEARRRLKRLENKIkelgpvnLAAI 992

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529   1999 SEVRDYKQRVHDVNNRVSELQR---QLQDANTEKNR-VEDRFLSVEKVVN 2044
Cdd:TIGR02168  993 EEYEELKERYDFLTAQKEDLTEakeTLEEAIEEIDReARERFKDTFDQVN 1042
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 526-1523 7.23e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.92  E-value: 7.23e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    526 ERNIELESRGDDSQRKIAELE---AELRRNREKLNEAQGALKKLHEMaQDSEKNVDGTVSIKRTRSLSpgktplppsEAL 602
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEdilNELERQLKSLERQAEKAERYKEL-KAELRELELALLVLRLEELR---------EEL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    603 RAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRAS 682
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    683 EAERVAAEKARKFLEDELAKLQASFQKSSTDDARkLRDEMDEhTNSIQEEFKTRIDELNRRVENllrennrlksevnpLK 762
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELES-LEAELEE-LEAELEELESRLEELEEQLET--------------LR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    763 DKYRDLENEYNSTQRRIEEKETQirysddirrniqkdLDDLREKYDRVHTDNEKILGELEHAQKAAHlaEQQLKEIKIQR 842
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEAR--------------LERLEDRRERLQQEIEELLKKLEEAELKEL--QAELEELEEEL 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    843 DDYQKQKDEHARHLFDIRhkleteikgrqdlekngarnnDELDKLRQtisdyesqinllrrhndeldttikghqgKITHL 922
Cdd:TIGR02168  450 EELQEELERLEEALEELR---------------------EELEEAEQ----------------------------ALDAA 480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    923 ENELHSRSGEIEKLNDLNQRLQKEKQDI---LNQKLKLDGDVQALKETIrKLENELEKlrnenkelvGKEARARDAANqq 999
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVkalLKNQSGLSGILGVLSELI-SVDEGYEA---------AIEAALGGRLQ-- 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1000 lsraNLLNKELEDTKQDLKHstdvnkqleqdirdLKErlANIGKGGRISRDSTTGTDggafgdrssvADPSRTRGAAGST 1079
Cdd:TIGR02168  549 ----AVVVENLNAAKKAIAF--------------LKQ--NELGRVTFLPLDSIKGTE----------IQGNDREILKNIE 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1080 VFVPAAEDIESrgggeidipssgdvihgrdgrdgrdagnrgthtitnTKERIERIEKNILDRYhddeLVEHKIREVNDRW 1159
Cdd:TIGR02168  599 GFLGVAKDLVK------------------------------------FDPKLRKALSYLLGGV----LVVDDLDNALELA 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1160 KRELERLenekddlerRIRELEDEL----SQIGRGNDKTENDITELKR---KHAAEIDKLKSDISALHDKhLSDLDDEKE 1232
Cdd:TIGR02168  639 KKLRPGY---------RIVTLDGDLvrpgGVITGGSAKTNSSILERRReieELEEKIEELEEKIAELEKA-LAELRKELE 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1233 QYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEwddfRNDADKEIQKWKTDA 1312
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER----LEEAEEELAEAEAEI 784

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1313 YTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSL 1392
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1393 EDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNafrektkq 1472
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV-------- 936

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   1473 adhlnqlasQFDTKLTKLRNELQDTNDKLITS----DTERNALRNELQKLSQELK 1523
Cdd:TIGR02168  937 ---------RIDNLQERLSEEYSLTLEEAEALenkiEDDEEEARRRLKRLENKIK 982
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 716-1538 2.05e-22

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 105.92  E-value: 2.05e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    716 RKLRDEMDEHTNSIqEEFKTRIDELNRRVENLLRENNRlKSEVNPLKDKYRDLE-----NEYNSTQRRIEEKETQI---- 786
Cdd:TIGR02169  173 EKALEELEEVEENI-ERLDLIIDEKRQQLERLRREREK-AERYQALLKEKREYEgyellKEKEALERQKEAIERQLasle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    787 RYSDDIRRNIQKDLDDLREKYDRVHTDNEKI--LGELEHAQKAAHLAEQQLKEIKIQR-----DDYQKQKDEHARHLFDI 859
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIkdLGEEEQLRVKEKIGELEAEIASLERsiaekERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    860 RHKLETEIkgrQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDL 939
Cdd:TIGR02169  331 IDKLLAEI---EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRE 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    940 NQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARdaanQQLSRAnllNKELEDTKQDLKH 1019
Cdd:TIGR02169  408 LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA----ADLSKY---EQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1020 STDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTR-----------GAAGSTVFVP----A 1084
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaaGNRLNNVVVEddavA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1085 AEDIE----SRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGTHTITNTKER---------------IERIE--KNILDRYH 1143
Cdd:TIGR02169  561 KEAIEllkrRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPkyepafkyvfgdtlvVEDIEaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1144 ----DDELVE---------HKIREVNDRWKRELERLEnekdDLERRIRELEDELSQIGRGNDKTENDITELKRKhaaeID 1210
Cdd:TIGR02169  641 mvtlEGELFEksgamtggsRAPRGGILFSRSEPAELQ----RLRERLEGLKRELSSLQSELRRIENRLDELSQE----LS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1211 KLKSDISALhDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYgqnqki 1290
Cdd:TIGR02169  713 DASRKIGEI-EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE------ 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1291 kdewddfRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELAD 1370
Cdd:TIGR02169  786 -------ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1371 TKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDankwRGELDAALREndiLKSNNTNMETDLTRLKNRLKSAEDALKELKN 1450
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKE----RDELEAQLRE---LERKIEELEAQIEKKRKRLSELKAKLEALEE 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1451 SLSHAKTEKERLQnafrEKTKQADHLNQLASQFDTKLTKLRnELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQ 1530
Cdd:TIGR02169  932 ELSEIEDPKGEDE----EIPEEELSLEDVQAELQRVEEEIR-ALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*...
gi 25151529   1531 RKSDEYQT 1538
Cdd:TIGR02169 1007 ERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 610-1400 2.27e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 99.37  E-value: 2.27e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    610 RNKDNDIQQLERKLKiaESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRAseaervAA 689
Cdd:TIGR02169  207 REKAERYQALLKEKR--EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE------LN 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    690 EKARKFLEDELAKLQA-----SFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDK 764
Cdd:TIGR02169  279 KKIKDLGEEEQLRVKEkigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEE 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    765 YRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDD 844
Cdd:TIGR02169  359 YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    845 YQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLEN 924
Cdd:TIGR02169  439 LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKA 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    925 ELHSRSGEIEKLNDLNQRLQKEKQDILNQKLK---LDGDVQAlKETIRKLENE---------LEKLRNENKEL-VGKEAR 991
Cdd:TIGR02169  519 SIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvVEDDAVA-KEAIELLKRRkagratflpLNKMRDERRDLsILSEDG 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    992 ARD-------------AANQQLSRANLLNKELEDTKQDLKHSTDVNkqLEQDIRDlkerlanigKGGRISrdsttgtdGG 1058
Cdd:TIGR02169  598 VIGfavdlvefdpkyePAFKYVFGDTLVVEDIEAARRLMGKYRMVT--LEGELFE---------KSGAMT--------GG 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1059 AFGDRSSVADPSRTRGAAGSTvfvpaAEDIESRGGGEIDIPSSGDVIHGR--DGRDGRDAGNRGTHTITNTKERIERIEK 1136
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRL-----RERLEGLKRELSSLQSELRRIENRldELSQELSDASRKIGEIEKEIEQLEQEEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1137 NILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTE-NDITELKRKHAAEIDKLKSD 1215
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1216 ISALhDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWD 1295
Cdd:TIGR02169  814 LREI-EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1296 DFRND---ADKEIQKWKTDAYTVRSEAKalettntALKAQLQAANDRIDHLTKTVNDHTSKV------RDLTSQVRHLED 1366
Cdd:TIGR02169  893 ELEAQlreLERKIEELEAQIEKKRKRLS-------ELKAKLEALEEELSEIEDPKGEDEEIPeeelslEDVQAELQRVEE 965

                          810       820       830
                   ....*....|....*....|....*....|....
gi 25151529   1367 ELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQ 1400
Cdd:TIGR02169  966 EIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLE 999
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 610-1037 1.02e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 1.02e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    610 RNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAA 689
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    690 EKARKFLEDELAKLQAsfQKSSTDDAR-KLRDEMDEHTNSIQEEfKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDL 768
Cdd:TIGR02168  746 EERIAQLSKELTELEA--EIEELEERLeEAEEELAEAEAEIEEL-EAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    769 ENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLddlrekydrvhtdnEKILGELEHAQkaahlaeQQLKEIKIQRDDYQKQ 848
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDI--------------ESLAAEIEELE-------ELIEELESELEALLNE 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    849 KDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLrrhndeldttikghQGKITHLenelhs 928
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL--------------EVRIDNL------ 941

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    929 rsgeIEKLNDLNQRLQkekQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKElvgkearARDAANQQLSRANLLNK 1008
Cdd:TIGR02168  942 ----QERLSEEYSLTL---EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLA-------AIEEYEELKERYDFLTA 1007

                          410       420
                   ....*....|....*....|....*....
gi 25151529   1009 ELEDTKQDLkhstdvnKQLEQDIRDLKER 1037
Cdd:TIGR02168 1008 QKEDLTEAK-------ETLEEAIEEIDRE 1029
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 512-988 3.31e-18

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 91.62  E-value: 3.31e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    512 ELHKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTvsikrtrslsp 591
Cdd:TIGR04523  211 QKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN----------- 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    592 gktplppsealravRNTFRNKDNDIQQLERKLKIAESQVKEFLNK-----FENADEARRRLDKQFA-------DAKREIS 659
Cdd:TIGR04523  280 --------------NKKIKELEKQLNQLKSEISDLNNQKEQDWNKelkseLKNQEKKLEEIQNQISqnnkiisQLNEQIS 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    660 NLQKSVD--EAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDDARKLRDEMDEHTNSIQEEFktri 737
Cdd:TIGR04523  346 QLKKELTnsESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEK---- 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    738 DELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKI 817
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    818 LGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEikgrqDLEKNGARNNDELDKLRQTISDYESQ 897
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD-----DFELKKENLEKEIDEKNKEIEELKQT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    898 INLLRRHNDELDTTIKGHQGKITHLENELHSR-------SGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRK 970
Cdd:TIGR04523  577 QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKekkisslEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656

                          490
                   ....*....|....*...
gi 25151529    971 LENELEKLRNENKELVGK 988
Cdd:TIGR04523  657 IRNKWPEIIKKIKESKTK 674
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 602-1378 7.32e-18

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 90.46  E-value: 7.32e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    602 LRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKS-------VDEAERNSRR 674
Cdd:TIGR04523   42 LKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlskinseIKNDKEQKNK 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    675 TDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSST--DDARKLRDEMDEHTNSIQEEF---KTRIDELN---RRVEN 746
Cdd:TIGR04523  122 LEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNkyNDLKKQKEELENELNLLEKEKlniQKNIDKIKnklLKLEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    747 LL-------RENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRysddirrNIQKDLDDLREKYDRVHTDNEKILG 819
Cdd:TIGR04523  202 LLsnlkkkiQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-------NTQTQLNQLKDEQNKIKKQLSEKQK 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    820 ELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEharhlfDIRHKLETEIKGRQ----DLEKNGARNNDELDKLRQTISDYE 895
Cdd:TIGR04523  275 ELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ------DWNKELKSELKNQEkkleEIQNQISQNNKIISQLNEQISQLK 348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 SQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKL----NDLNQRLQKEKQD----------ILNQKLKLDGDV 961
Cdd:TIGR04523  349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqiNDLESKIQNQEKLnqqkdeqikkLQQEKELLEKEI 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    962 QALKETIRKLENELEKLRNEN--KELVGKE-ARARDAANQQLS----RANLLNKELEDTKQDLKHSTDVNKQLEQDIRDL 1034
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDsvKELIIKNlDNTRESLETQLKvlsrSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1035 KERLANIgkggrisrdsttgtdggafgdrssvadpsrtrgaagstvfvpaaediesrgggeidipssgdvihgrdgrdgr 1114
Cdd:TIGR04523  509 EEKVKDL------------------------------------------------------------------------- 515

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1115 dagnrgthtitntKERIERIEKNIldryhddelvehkirevndrwkrelERLENEKDDLERRIRELEDELSQIGRGNDKt 1194
Cdd:TIGR04523  516 -------------TKKISSLKEKI-------------------------EKLESEKKEKESKISDLEDELNKDDFELKK- 556

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1195 eNDITELKRKHAAEIDKLKSDISALHDKHlSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKR 1274
Cdd:TIGR04523  557 -ENLEKEIDEKNKEIEELKQTQKSLKKKQ-EEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIK 634

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1275 DYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVrseAKALETTNTALKAQLQAANDRIDHLTKT-----VND 1349
Cdd:TIGR04523  635 NIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKI---DDIIELMKDWLKELSLHYKKYITRMIRIkdlpkLEE 711

                          810       820
                   ....*....|....*....|....*....
gi 25151529   1350 HTSKVRDLTSQVRHLEDELADTKGNLVQK 1378
Cdd:TIGR04523  712 KYKEIEKELKKLDEFSKELENIIKNFNKK 740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 741-1504 8.25e-18

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 90.46  E-value: 8.25e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    741 NRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGE 820
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    821 LEHAQKAAHLAEQQLKEIKiqrddyqKQKDEHARHLFDIRhkleTEIKgrqDLEKNGARNNDELDKLRQTISDYESQINL 900
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLE-------KQKKENKKNIDKFL----TEIK---KKEKELEKLNNKYNDLKKQKEELENELNL 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    901 LRRHNDELDTTIKghqgKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRN 980
Cdd:TIGR04523  178 LEKEKLNIQKNID----KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    981 ENKELVGKEARARD---AANQQLSRANLLNKELEDTKQDLKHS-TDVNKQLEQDI-RDLKERLANIGKggrisrdsttgt 1055
Cdd:TIGR04523  254 QLNQLKDEQNKIKKqlsEKQKELEQNNKKIKELEKQLNQLKSEiSDLNNQKEQDWnKELKSELKNQEK------------ 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1056 dggafgdrssvadpsrtrgaagstvfvpAAEDIESRgggeidipssgdvihgrdgrdgrdagnrgthtITNTKERIERIE 1135
Cdd:TIGR04523  322 ----------------------------KLEEIQNQ--------------------------------ISQNNKIISQLN 341

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1136 KNILDryhddelvehkirevndrWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKrkhaAEIDKLKSD 1215
Cdd:TIGR04523  342 EQISQ------------------LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE----SQINDLESK 399

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1216 I------SALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQK 1289
Cdd:TIGR04523  400 IqnqeklNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK 479

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1290 IKDEWDDFRNDADKEIQKWKTdaytvrseakalettntaLKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELA 1369
Cdd:TIGR04523  480 IKQNLEQKQKELKSKEKELKK------------------LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1370 DTKGNLVQKEMDLESTQnrlrsLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELK 1449
Cdd:TIGR04523  542 DLEDELNKDDFELKKEN-----LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLE 616

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   1450 NSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITS 1504
Cdd:TIGR04523  617 KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 793-1607 4.71e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 4.71e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    793 RRNIQKDLDDLREKYDRVhtdnEKILGELEhaqkaahlaeQQLKEIKIQRD---DYQKQKDEharhLFDIRHKLETeikg 869
Cdd:TIGR02168  174 RKETERKLERTRENLDRL----EDILNELE----------RQLKSLERQAEkaeRYKELKAE----LRELELALLV---- 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    870 rQDLEkngaRNNDELDKLRQTISDYESQINllrrhndELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQD 949
Cdd:TIGR02168  232 -LRLE----ELREELEELQEELKEAEEELE-------ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    950 ILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQ 1029
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1030 DIRDLKERLANIgkggrisrdsttgtdggafgdRSSVADPSRTRGAAGSTVfvpaaEDIESRgggeidipssgdvihgRD 1109
Cdd:TIGR02168  380 QLETLRSKVAQL---------------------ELQIASLNNEIERLEARL-----ERLEDR----------------RE 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1110 GRDGRDAGNRGTHTITNTKERIERIEknildryhDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGR 1189
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQAELE--------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1190 GNDKTENDITELKRKH--AAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVEN-LKSVEDDLRDKLNNLEKQLADSLnRE 1266
Cdd:TIGR02168  490 RLDSLERLQENLEGFSegVKALLKNQSGLSGILGV-LSELISVDEGYEAAIEAaLGGRLQAVVVENLNAAKKAIAFL-KQ 567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1267 NELER-----EKRDYDEKINSLYGQNQK-------IKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALE--------TTN 1326
Cdd:TIGR02168  568 NELGRvtflpLDSIKGTEIQGNDREILKniegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklrpgYRI 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1327 TALKAQL-----------QAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQ 1395
Cdd:TIGR02168  648 VTLDGDLvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1396 HSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKElknslshAKTEKERLQnafrektKQADH 1475
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE-------AEAEIEELE-------AQIEQ 793

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1476 LNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEyqttIDDLAHSHRVSEDSRL 1555
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED----IESLAAEIEELEELIE 869

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 25151529   1556 NALQELEArkyeindLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQ 1607
Cdd:TIGR02168  870 ELESELEA-------LLNERASLEEALALLRSELEELSEELRELESKRSELR 914
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1124-1614 5.35e-17

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 87.77  E-value: 5.35e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1124 ITNTKERIERIEKNILDryhddelVEHKIREVNDRWKR---ELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITE 1200
Cdd:TIGR04523  119 KNKLEVELNKLEKQKKE-------NKKNIDKFLTEIKKkekELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1201 LKRKHAAEIDKLkSDISALHDKH------LSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLadsLNRENELEREKR 1274
Cdd:TIGR04523  192 IKNKLLKLELLL-SNLKKKIQKNkslesqISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQL---NQLKDEQNKIKK 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1275 DYDEKINSLYGQNQKIKD---------------------EWDDFRNDADKEIQKWKTDAYT------------------V 1315
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKElekqlnqlkseisdlnnqkeqDWNKELKSELKNQEKKLEEIQNqisqnnkiisqlneqisqL 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQ 1395
Cdd:TIGR04523  348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1396 HSTLQSDANKWRGELDAalrendiLKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADH 1475
Cdd:TIGR04523  428 IERLKETIIKNNSEIKD-------LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKK 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1476 LNQLASQFDTK---LTKLRNELQDTNDKLITSDTERNA----LRNELQKLSQELKFgnEQIQRKSDEYQTTIDDLAHSHR 1548
Cdd:TIGR04523  501 LNEEKKELEEKvkdLTKKISSLKEKIEKLESEKKEKESkisdLEDELNKDDFELKK--ENLEKEIDEKNKEIEELKQTQK 578

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   1549 VSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVI 1614
Cdd:TIGR04523  579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 516-1278 1.29e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.03  E-value: 1.29e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    516 ELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNvdgtvsIKRTRslspgktp 595
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ------KQILR-------- 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    596 lppsEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRT 675
Cdd:TIGR02168  309 ----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    676 DDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTdDARKLRDEMDEHTnsiQEEFKTRIDELNRRVENLLRENNRLK 755
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ-EIEELLKKLEEAE---LKELQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    756 SEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKY--------------DRVHTDN------E 815
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqsglsgilgvlsELISVDEgyeaaiE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    816 KILGELEHA-----QKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQT 890
Cdd:TIGR02168  541 AALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    891 I-------SDYESQINLLRRHN-----------------------DELDTTIKGHQGKITHLENELHSRSGEIEKLNDLN 940
Cdd:TIGR02168  621 LlggvlvvDDLDNALELAKKLRpgyrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKAL 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    941 QRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHS 1020
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1021 TDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTRGAAGSTvfvpaAEDIESRgggeidips 1100
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR-----LEDLEEQ--------- 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1101 sgdvihgrdgrdgrdagnrgthtITNTKERIERIEKNILDryhddelvehkIREVNDRWKRELERLENEKDDLERRIREL 1180
Cdd:TIGR02168  847 -----------------------IEELSEDIESLAAEIEE-----------LEELIEELESELEALLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1181 EDELSQIGRGNDKTENDITELKRKHAA----------EIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRD 1250
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEElreklaqlelRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972

                          810       820       830
                   ....*....|....*....|....*....|..
gi 25151529   1251 KLNNLEKQLAD----SLNRENELEREKRDYDE 1278
Cdd:TIGR02168  973 RLKRLENKIKElgpvNLAAIEEYEELKERYDF 1004
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1162-1605 1.45e-16

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 86.23  E-value: 1.45e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1162 ELERLENEKDDLERRIRELEDELSQIgrgnDKTENDITELKRKHAAEIDKLKSDISALHdkhlSDLDDEKEQYGKAVENL 1241
Cdd:TIGR04523   55 ELKNLDKNLNKDEEKINNSNNKIKIL----EQQIKDLNDKLKKNKDKINKLNSDLSKIN----SEIKNDKEQKNKLEVEL 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1242 KSVEDDLRDK----------LNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWkTD 1311
Cdd:TIGR04523  127 NKLEKQKKENkknidkflteIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLL-SN 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1312 AYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRS 1391
Cdd:TIGR04523  206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1392 LEDQHSTLQSDANKWRGELDAALreNDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTK 1471
Cdd:TIGR04523  286 LEKQLNQLKSEISDLNNQKEQDW--NKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1472 QADHLNQlasqfdtKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQT---TIDDLAHSHR 1548
Cdd:TIGR04523  364 ELEEKQN-------EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELlekEIERLKETII 436

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529   1549 VSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRR 1605
Cdd:TIGR04523  437 KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 323-1042 1.51e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 1.51e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    323 EMIARLDEERRRSDEYRMQWENERQKSLSLEDENDRLRREFERYANDSKDKE--KTFINRERN--------LAQYLSDEQ 392
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEqqKQILRERLAnlerqleeLEAQLEELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    393 RKMLDLWTELQRVRKQFSDLKTHTEEdLDKQKAEFTRAIRNVNNISR--NAAFSAGAGDglgLYGLEDGGDVNRTTNNYE 470
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELES-LEAELEELEAELEELESRLEelEEQLETLRSK---VAQLELQIASLNNEIERL 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    471 KVFIETIKRMNGTGGAGSASSADLLEELRKIRGGGSSEGDAELHKELMTKYEESIERNIELESRgddsqrkIAELEAELR 550
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE-------LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    551 RNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSLSPGKTPLPpsealravrntfrnkdndiqqlerklkiaeSQV 630
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL------------------------------SEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    631 KEFLNKFENADEA--RRRLD----KQFADAKREISNLQKSvdEAERN-----SRRTDDKLRASEAERVAAEKARKFLEDE 699
Cdd:TIGR02168  529 ISVDEGYEAAIEAalGGRLQavvvENLNAAKKAIAFLKQN--ELGRVtflplDSIKGTEIQGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    700 LAKLQASFQK----------------SSTDDARKLRDEM-------------------DEHTNSIQEEFKTRIDELNRRV 744
Cdd:TIGR02168  607 LVKFDPKLRKalsyllggvlvvddldNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    745 ENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHA 824
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    825 QKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLEteikgrqDLEKNGARNNDELDKLRQTISDYESQINLLRRH 904
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD-------ELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    905 NDELDTTIKGHQGKITHLEnelhsrsGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKE 984
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLA-------AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529    985 LVGKEARARDAANQ--------QLSRANLLNK-------ELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIG 1042
Cdd:TIGR02168  913 LRRELEELREKLAQlelrleglEVRIDNLQERlseeyslTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1731-2221 1.69e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:COG1196  247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1811 SQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRtdldnahtdiRSLRDKEEQWDSSRFQLETKMRESD 1890
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE----------AELAEAEEELEELAEELLEALRAAA 396

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1891 SDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLK 1970
Cdd:COG1196  397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNR--VSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRT 2048
Cdd:COG1196  477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2049 TETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRnssqlsdgwkkekITLLKKIELLENEKRrtDAAIRETALQRE 2128
Cdd:COG1196  557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR-------------GAIGAAVDLVASDLR--EADARYYVLGDT 621

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2129 AIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQ 2208
Cdd:COG1196  622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                        490
                 ....*....|...
gi 25151529 2209 LEDQIAILRDQLD 2221
Cdd:COG1196  702 EEEEERELAEAEE 714
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 689-1275 1.84e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.84e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  689 AEKARKF--LEDELAKLQASfqksstddARKLRDEmdeHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYR 766
Cdd:COG1196  209 AEKAERYreLKEELKELEAE--------LLLLKLR---ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  767 DLENEYNSTQRRIEEKETQIRysddirrNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQ 846
Cdd:COG1196  278 ELELELEEAQAEEYELLAELA-------RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  847 KQKDEHARHLFDIRHKLETEIKGRQDLEkngarnnDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENEL 926
Cdd:COG1196  351 EELEEAEAELAEAEEALLEAEAELAEAE-------EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  927 HSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLL 1006
Cdd:COG1196  424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1007 NKELEDTKQDLKHS-----------------------------------TDVNKQLEQDIRDLKER---------LANIG 1042
Cdd:COG1196  504 EGFLEGVKAALLLAglrglagavavligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAkagratflpLDKIR 583

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1043 KGGRISRDSTTGTDGGAFGDRSS--VADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRG 1120
Cdd:COG1196  584 ARAALAAALARGAIGAAVDLVASdlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1121 THTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTEN---D 1197
Cdd:COG1196  664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEellE 743

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1198 ITELKRKHAAEIDKLKSDISALhDKHLSDLDDEKEQYGK----AVENLKSVE---DDLRDKLNNLEKQLADSLNRENELE 1270
Cdd:COG1196  744 EEELLEEEALEELPEPPDLEEL-ERELERLEREIEALGPvnllAIEEYEELEeryDFLSEQREDLEEARETLEEAIEEID 822


                 ....*
gi 25151529 1271 REKRD 1275
Cdd:COG1196  823 RETRE 827
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 511-1043 1.54e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  511 AELHKELMTKYEESIERNIELESRGDD---SQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTvsikrtr 587
Cdd:COG1196  263 AELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL------- 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  588 slspgktplppSEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDE 667
Cdd:COG1196  336 -----------EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  668 AERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDDARKLRDEmdEHTNSIQEEFKTRIDELNRRVENL 747
Cdd:COG1196  405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE--EALLELLAELLEEAALLEAALAEL 482

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  748 LRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEketqirysdDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQ-- 825
Cdd:COG1196  483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLL---------AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIvv 553

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  826 ---KAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGR----QDLEKNGARNNDELDKLRQTISDY---E 895
Cdd:COG1196  554 eddEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvaSDLREADARYYVLGDTLLGRTLVAarlE 633

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  896 SQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENEL 975
Cdd:COG1196  634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  976 EKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:COG1196  714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 732-1366 1.66e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.06  E-value: 1.66e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  732 EFKTRIDElnRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVH 811
Cdd:COG1196  217 ELKEELKE--LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  812 TDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTI 891
Cdd:COG1196  295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  892 SDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEklndlnqRLQKEKQDILNQKLKLDGDVQALKETIRKL 971
Cdd:COG1196  375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE-------RLEEELEELEEALAELEEEEEEEEEALEEA 447

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  972 ENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGrisrDS 1051
Cdd:COG1196  448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG----LA 523

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1052 TTGTDGGAFGDRSSVADPSRTrGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGTHTITNTKERI 1131
Cdd:COG1196  524 GAVAVLIGVEAAYEAALEAAL-AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1132 ERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRgndktenDITELKRKHAAEIDK 1211
Cdd:COG1196  603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG-------SLTGGSRRELLAALL 675

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1212 LKSDIsalhdkhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIK 1291
Cdd:COG1196  676 EAEAE-------LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1292 DEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLtktvndhTSKVRDLTSQVRHLED 1366
Cdd:COG1196  749 EEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEEYEELEERYDFL-------SEQREDLEEARETLEE 816
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 541-1043 1.96e-15

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 82.76  E-value: 1.96e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    541 KIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTvsIKRTRSLSPGKTPLPPS-----EALRAVRNTFRNKD-- 613
Cdd:TIGR04523  125 ELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL--KKQKEELENELNLLEKEklniqKNIDKIKNKLLKLEll 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    614 -NDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKA 692
Cdd:TIGR04523  203 lSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    693 RKFLEDELAKLQASFQKsstddarkLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENN----RLKSEVNPLKDKYRDL 768
Cdd:TIGR04523  283 IKELEKQLNQLKSEISD--------LNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNkiisQLNEQISQLKKELTNS 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    769 ENEYNSTQRRIEEKETQIRysddirrNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDdyqkq 848
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIE-------KLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKE----- 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    849 kdeharhlfdirhKLETEIkgrQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHS 928
Cdd:TIGR04523  423 -------------LLEKEI---ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    929 RSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKearaRDAANQQLSRANL--- 1005
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE----LNKDDFELKKENLeke 562

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 25151529   1006 ---LNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:TIGR04523  563 ideKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK 603
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 765-1529 5.58e-15

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 81.22  E-value: 5.58e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    765 YRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDD-LREKYDRVHTDNEKIlgelehaqkaaHLAEQQLKEIKiqrd 843
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKnLNKDEEKINNSNNKI-----------KILEQQIKDLN---- 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    844 dyqkqkdeharhlfdirHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLE 923
Cdd:TIGR04523   89 -----------------DKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKE 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    924 NELhsrsgeiEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEarardaanqqlSRA 1003
Cdd:TIGR04523  152 KEL-------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKI-----------QKN 213

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1004 NLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKggrisrdsttgtdggafgdrssvadpsrtrgaagstvfvp 1083
Cdd:TIGR04523  214 KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT---------------------------------------- 253

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1084 aaediesrgggeidipssgdvihgrdgrdgrdagnrgthTITNTKERIERIEKNILDRYHDDELVEHKIREVNDR---WK 1160
Cdd:TIGR04523  254 ---------------------------------------QLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQlnqLK 294

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1161 RELERLENEKD-----DLERRIRELEDELSQIGRGNDKTENDITELKRkhaaEIDKLKSDISALHDKHLSdLDDEKEQYG 1235
Cdd:TIGR04523  295 SEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNE----QISQLKKELTNSESENSE-KQRELEEKQ 369

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1236 KAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIkdewddfrndaDKEIQKWKTDAYTV 1315
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL-----------EKEIERLKETIIKN 438

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTNTALKAQLQAANDRIDHLTKtvndhtsKVRDLTSQVRHLEDELADTKGNLVQKEMDLES-------TQNR 1388
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLET-------QLKVLSRSINKIKQNLEQKQKELKSKEKELKKlneekkeLEEK 511

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1389 LRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTR--LKNRLKSAEDALKELKNSLSHAKTEKERLQNAF 1466
Cdd:TIGR04523  512 VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKenLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELI 591

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529   1467 REKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQI 1529
Cdd:TIGR04523  592 DQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1236-1888 9.36e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 9.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1236 KAVENLKSVEDDL---RDKLNNLEKQLaDSLNRENELEREKRDYDEKINSLygQNQKIKDEWDDFRND---ADKEIQKWK 1309
Cdd:COG1196  176 EAERKLEATEENLerlEDILGELERQL-EPLERQAEKAERYRELKEELKEL--EAELLLLKLRELEAEleeLEAELEELE 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1310 TDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRL 1389
Cdd:COG1196  253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL 332

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1390 RSLEDQhstlqsdankwrgeldaalrendilksnntnmetdLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREK 1469
Cdd:COG1196  333 EELEEE-----------------------------------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1470 TKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKfgneqiqrksdEYQTTIDDLAHSHRV 1549
Cdd:COG1196  378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA-----------ELEEEEEEEEEALEE 446

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1550 SEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTfvdggagyVDG 1629
Cdd:COG1196  447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL--------LAG 518

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1630 VPGGTSVIGGGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADFSSGRPGAAS 1709
Cdd:COG1196  519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1710 AG-GRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNL 1788
Cdd:COG1196  599 AAvDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1789 QDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSL 1868
Cdd:COG1196  679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                        650       660
                 ....*....|....*....|
gi 25151529 1869 RDKEEQWDSSRFQLETKMRE 1888
Cdd:COG1196  759 PPDLEELERELERLEREIEA 778
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 896-1613 1.16e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 80.55  E-value: 1.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 SQINLLRRHNDELDTTIK--GHQGKiTHLENELHSRSGEIEklnDLNQRLQKEKQdiLNQKLKLdgdvqALKETIRKLEN 973
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKiiAYPGK-EHIERVLEEYSHQVK---DLQRRLNESNE--LHEKQKF-----YLRQSVIDLQT 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    974 ELEKLRNENKELVgkEARARDAANQQLSRANLLNK--ELEDT---KQDLKHstDVNKQLEQDIRDLKERLANIGKGGRIS 1048
Cdd:pfam15921  118 KLQEMQMERDAMA--DIRRRESQSQEDLRNQLQNTvhELEAAkclKEDMLE--DSNTQIEQLRKMMLSHEGVLQEIRSIL 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1049 RDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGrdgrdgrDAGNRGTHTITNTK 1128
Cdd:pfam15921  194 VDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKS-------ESQNKIELLLQQHQ 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1129 ERIERI----EKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIgrgndktENDITELKRK 1204
Cdd:pfam15921  267 DRIEQLisehEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQL-------RSELREAKRM 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1205 HAAEIDKLKSDIsALHDKHLSDLDDEKEQYGKAVENLksveDDlrdklnNLEKQLADSLNRENELEREKRdydekinsly 1284
Cdd:pfam15921  340 YEDKIEELEKQL-VLANSELTEARTERDQFSQESGNL----DD------QLQKLLADLHKREKELSLEKE---------- 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1285 gQNQKIkdeWD-DFRNDADKEIQKWKTDAYTVrsEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRH 1363
Cdd:pfam15921  399 -QNKRL---WDrDTGNSITIDHLRRELDDRNM--EVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLES 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1364 LEDELADTKGNLVQKEMDLESTQnrlRSLEDQHSTLQ----------SDANKWRGELDAALRENDILKSNN---TNMETD 1430
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESSE---RTVSDLTASLQekeraieatnAEITKLRSRVDLKLQELQHLKNEGdhlRNVQTE 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1431 LTRLKNRLKSAEDALKELKNSL--------SHAKT------EKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQD 1496
Cdd:pfam15921  550 CEALKLQMAEKDKVIEILRQQIenmtqlvgQHGRTagamqvEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSD 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1497 ---TNDKLITSDTER------------------NALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSE---D 1552
Cdd:pfam15921  630 lelEKVKLVNAGSERlravkdikqerdqllnevKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQselE 709

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   1553 SRLNALQELE------------------ARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRV 1613
Cdd:pfam15921  710 QTRNTLKSMEgsdghamkvamgmqkqitAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
520-1043 1.44e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 80.11  E-value: 1.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   520 KYEESIERNI-ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKnvdgtvSIKRTRSLspgktplpp 598
Cdd:PRK03918  186 KRTENIEELIkEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE------LEKELESL--------- 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   599 SEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEfLNKFENADEARRRLDK---QFADAKREISNLQKSVDEAERNSRRT 675
Cdd:PRK03918  251 EGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEER 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   676 DDKLRASEAERVAAEKARKFLEDELAKLQASFQKssTDDARKLRDEMDEH----TNSIQEEFKTRIDELNRRVENLLREN 751
Cdd:PRK03918  330 IKELEEKEERLEELKKKLKELEKRLEELEERHEL--YEEAKAKKEELERLkkrlTGLTPEKLEKELEELEKAKEEIEEEI 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   752 NRLKSEVNPLKDKYRDLE---NEYNSTQRRI----------EEKETQIRYSDDIRR--NIQKDLDDLREKYDRVHTDNEK 816
Cdd:PRK03918  408 SKITARIGELKKEIKELKkaiEELKKAKGKCpvcgrelteeHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELEK 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   817 ILGELEHAQKAAHLAEqQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQdlekngARNNDELDKLRQTISDYES 896
Cdd:PRK03918  488 VLKKESELIKLKELAE-QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI------KSLKKELEKLEELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   897 QINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRL---QKEKQDILNQKLKLDGDVQALKETIRKLEN 973
Cdd:PRK03918  561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELkdaEKELEREEKELKKLEEELDKAFEELAETEK 640

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529   974 ELEKLRNENKELVGK--EARARDAANQQLSranlLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:PRK03918  641 RLEELRKELEELEKKysEEEYEELREEYLE----LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1731-2221 1.66e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:COG1196  240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1811 SQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESD 1890
Cdd:COG1196  320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1891 SDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKtshEYQLLK 1970
Cdd:COG1196  400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE---EAALLE 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNR--------------------VSELQRQLQDANTEKN 2030
Cdd:COG1196  477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavavligveaayeaalEAALAAALQNIVVEDD 556

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2031 RVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLE 2110
Cdd:COG1196  557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2111 NEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCA--QLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEK 2188
Cdd:COG1196  637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLeaEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                        490       500       510
                 ....*....|....*....|....*....|...
gi 25151529 2189 GQIEKVIENRERTHRNRIKQLEDQIAILRDQLD 2221
Cdd:COG1196  717 LEEELEEEALEEQLEAEREELLEELLEEEELLE 749
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1778-2115 7.69e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 7.69e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1778 ETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRqmKSKMVAAeLQARGKEAQLRHLNEQLKNLRTD 1857
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRE--LELALLV-LRLEELREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1858 LDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDK 1937
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1938 LRRDLTKAESVENELRKtidiqsktshEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSE 2017
Cdd:TIGR02168  335 LAEELAELEEKLEELKE----------ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2018 LQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTEtdLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKK 2097
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          330
                   ....*....|....*...
gi 25151529   2098 EKITLLKKIELLENEKRR 2115
Cdd:TIGR02168  483 ELAQLQARLDSLERLQEN 500
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 493-1275 2.13e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    493 DLLEELRKIrgggssEGDAELH-KELMTKYEESIERNI-ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKL--HE 568
Cdd:TIGR02169  215 ALLKEKREY------EGYELLKeKEALERQKEAIERQLaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEE 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    569 MAQDSEKNVDGTVSIKRTRSlspgktplppsealravrnTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLD 648
Cdd:TIGR02169  289 QLRVKEKIGELEAEIASLER-------------------SIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    649 KQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASfQKSSTDDARKLRDEMDEHTNS 728
Cdd:TIGR02169  350 KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRE-LDRLQEELQRLSEELADLNAA 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    729 I------QEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDD 802
Cdd:TIGR02169  429 IagieakINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    803 LREKYDRVHTDNEKILGEL--------EHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARH----------LFDIRHKLE 864
Cdd:TIGR02169  509 GRAVEEVLKASIQGVHGTVaqlgsvgeRYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRrkagratflpLNKMRDERR 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    865 TEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDeldtTIKGHQGKI--THLENELHSRSGEI------EKL 936
Cdd:TIGR02169  589 DLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIE----AARRLMGKYrmVTLEGELFEKSGAMtggsraPRG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    937 NDLNQRLQKEKQDILNQKL-KLDGDVQALKETIRKLENELEKLRNENKELVGKEARARdaanqqlSRANLLNKELEDTKQ 1015
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLeGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE-------KEIEQLEQEEEKLKE 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1016 DLKHSTDVNKQLEQDIRDLKERLANIGKggRIS-RDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVpaaEDIESRGGG 1094
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSELKELEA--RIEeLEEDLHKLEEALNDLEARLSHSRIPEIQAELSKL---EEEVSRIEA 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1095 EIDipsSGDVIHGRDGRDGRDAGNRgthtITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKR---ELERLENEKD 1171
Cdd:TIGR02169  813 RLR---EIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEleaALRDLESRLG 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1172 DLERRIRELEDELSQIGRGNDKTENDItELKRKHAAEidkLKSDISALHDKhLSDLDDEKEQ----------YGKAVENL 1241
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQI-EKKRKRLSE---LKAKLEALEEE-LSEIEDPKGEdeeipeeelsLEDVQAEL 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529   1242 KSVE------------------------DDLRDKLNNLEKQLADSLNRENELEREKRD 1275
Cdd:TIGR02169  961 QRVEeeiralepvnmlaiqeyeevlkrlDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1780-2099 3.16e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 3.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1780 RYRNIEDNLQDAEEE-----RRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNL 1854
Cdd:COG1196  214 RYRELKEELKELEAEllllkLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1855 RTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESdsdtnkyQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDD 1934
Cdd:COG1196  294 LAELARLEQDIARLEERRRELEERLEELEEELAEL-------EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1935 TDKLRRDLTKAESVENELRKtidiqsktshEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNR 2014
Cdd:COG1196  367 LLEAEAELAEAEEELEELAE----------ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2015 VSELQRQLQDANTEKNRVEDRFLSVEKVVntmrtteTDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDG 2094
Cdd:COG1196  437 EEEEEEALEEAAEEEAELEEEEEALLELL-------AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509


                 ....*
gi 25151529 2095 WKKEK 2099
Cdd:COG1196  510 VKAAL 514
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 724-1522 4.25e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.54  E-value: 4.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    724 EHTNSIQEEFKTRIDELNRRvenlLRENNRLKSevnplKDKYRdLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDL 803
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRR----LNESNELHE-----KQKFY-LRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    804 REKY-DRVHtdnekilgELEHAQKaahLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLeteikgrQDLEKNGARNND 882
Cdd:pfam15921  144 RNQLqNTVH--------ELEAAKC---LKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL-------VDFEEASGKKIY 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    883 ELDKLrqTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEklNDLNQRLQKEKQDILNQKLKLDGDVQ 962
Cdd:pfam15921  206 EHDSM--STMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQ--NKIELLLQQHQDRIEQLISEHEVEIT 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    963 ALKETIRKLENELEKLRNEnKELVGKEARARDAAN-QQLSranllnkELEDTKQDLKHSTDVNKQLEQD-IRDLKERL-- 1038
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQ-LEIIQEQARNQNSMYmRQLS-------DLESTVSQLRSELREAKRMYEDkIEELEKQLvl 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1039 ANigkggriSRDSTTGTDGGAFGDRSSVADPSRTRGAAGstvfvpaaediesrgggeidipssgdvIHGRDgrdgrdagn 1118
Cdd:pfam15921  354 AN-------SELTEARTERDQFSQESGNLDDQLQKLLAD---------------------------LHKRE--------- 390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1119 rgtHTITNTKERieriEKNILDRYHDDEL-VEHKIREVNDRwKRELERLENEKDDLERRIR-ELEDELSQIGRGNDKTEN 1196
Cdd:pfam15921  391 ---KELSLEKEQ----NKRLWDRDTGNSItIDHLRRELDDR-NMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEK 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1197 ---------DITELKRKHAAEIDKLKSDISAlHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNREN 1267
Cdd:pfam15921  463 vssltaqleSTKEMLRKVVEELTAKKMTLES-SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGD 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1268 ELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTdaytvrseAKALETTNTALKAQLQAANDRIDHLTKTV 1347
Cdd:pfam15921  542 HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT--------AGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1348 NDHTSKVRDLTSQVRHLEDEladtKGNLVQkemdleSTQNRLRSLED---QHSTLQSDANKWRGELDAALRENDILKSNN 1424
Cdd:pfam15921  614 DKKDAKIRELEARVSDLELE----KVKLVN------AGSERLRAVKDikqERDQLLNEVKTSRNELNSLSEDYEVLKRNF 683

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1425 TN----METDLTRLKNRLKSAEDALKELKNSLshaktekERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDK 1500
Cdd:pfam15921  684 RNkseeMETTTNKLKMQLKSAQSELEQTRNTL-------KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEA 756

                          810       820
                   ....*....|....*....|..
gi 25151529   1501 LITSDTERNALRNELQKLSQEL 1522
Cdd:pfam15921  757 MTNANKEKHFLKEEKNKLSQEL 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1937-2221 4.51e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 4.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1937 KLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVS 2016
Cdd:COG1196  219 KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2017 ELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWK 2096
Cdd:COG1196  299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2097 KEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELykncaqlqqqiAQLEMENGNRILELTNKQREE 2176
Cdd:COG1196  379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL-----------EEALAELEEEEEEEEEALEEA 447

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 25151529 2177 QERQLIRMRQEKGQIEKVIENRERThrnriKQLEDQIAILRDQLD 2221
Cdd:COG1196  448 AEEEAELEEEEEALLELLAELLEEA-----ALLEAALAELLEELA 487
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
539-1041 6.62e-13

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 74.57  E-value: 6.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  539 QRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDgtvsikrtrslspgktplppsEALRAVRNtfrNKDNDIQQ 618
Cdd:COG4913  287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELD---------------------ELEAQIRG---NGGDRLEQ 342

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  619 LERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQK----SVDEAERNSRRTDDKLRASEAERVAAEKARK 694
Cdd:COG4913  343 LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAeaaaLLEALEEELEALEEALAEAEAALRDLRRELR 422

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  695 FLEDELAKLQASfQKSSTDDARKLRDEMDEHTNSIQEE---------------------------FKTRI-------DEL 740
Cdd:COG4913  423 ELEAEIASLERR-KSNIPARLLALRDALAEALGLDEAElpfvgelievrpeeerwrgaiervlggFALTLlvppehyAAA 501

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  741 NRRVENL-LREnnRLKSE-VNPLKDKYRDLENEYNSTQRRIEEKETQIRY-----------------SDDIRRNIQ---- 797
Cdd:COG4913  502 LRWVNRLhLRG--RLVYErVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwleaelgrrfdyvcvdsPEELRRHPRaitr 579

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  798 ----KDLDDLREKYDRVHTDNEKILG------------ELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLF---- 857
Cdd:COG4913  580 agqvKGNGTRHEKDDRRRIRSRYVLGfdnraklaaleaELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswd 659

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  858 DIRHK-LETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENEL---------H 927
Cdd:COG4913  660 EIDVAsAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELdelqdrleaA 739

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  928 SRSGEIEKLNDLNQRLQKEKQDILNQKLK--LDGDVQALKETIRKLENELEKLRNENKE---LVGKEARARDAANQQLSR 1002
Cdd:COG4913  740 EDLARLELRALLEERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMRAFNRewpAETADLDADLESLPEYLA 819

                        570       580       590       600       610
                 ....*....|....*....|....*....|....*....|....*....|
gi 25151529 1003 --ANLLNKELEDTKQDLKHS---------TDVNKQLEQDIRDLKERLANI 1041
Cdd:COG4913  820 llDRLEEDGLPEYEERFKELlnensiefvADLLSKLRRAIREIKERIDPL 869
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1738-2146 6.75e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 74.29  E-value: 6.75e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1738 TLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEER---------------------R 1796
Cdd:TIGR04523  205 NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQnkikkqlsekqkeleqnnkkiK 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1797 ALESRLQSAKTLL-----RSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTD------- 1864
Cdd:TIGR04523  285 ELEKQLNQLKSEIsdlnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESEnsekqre 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1865 --------------IRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELdgalrlsDSKVQD 1930
Cdd:TIGR04523  365 leekqneieklkkeNQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERL-------KETIIK 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1931 MKDDTDKLRRDLTKAESVENELRKTIDIQ----SKTSHEYQLLKDQLLNTQNELngannrkQQLENELLNVRSEVRDYKQ 2006
Cdd:TIGR04523  438 NNSEIKDLTNQDSVKELIIKNLDNTRESLetqlKVLSRSINKIKQNLEQKQKEL-------KSKEKELKKLNEEKKELEE 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2007 RVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETdlRQQLETAKNEKRvatKELEDLKRRLAQLENERR 2086
Cdd:TIGR04523  511 KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK--KENLEKEIDEKN---KEIEELKQTQKSLKKKQE 585

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529   2087 NSSQLSDGWKKEKITLLKKIEL-------LENEKRRTDAAIRETALQREAIEKSLNAMERENKELYK 2146
Cdd:TIGR04523  586 EKQELIDQKEKEKKDLIKEIEEkekkissLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1835-2212 1.43e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.43e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1835 LQARGKEA--QLRHLNEQLKNLrtdldnahTDIrsLRDKEEQWDSSRFQLETkmresdsdTNKYQ-LQIASFESERQILT 1911
Cdd:TIGR02168  170 YKERRKETerKLERTRENLDRL--------EDI--LNELERQLKSLERQAEK--------AERYKeLKAELRELELALLV 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1912 EKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRktiDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLE 1991
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR---LEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1992 NELLNVrseVRDYKQrvhdVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNtmrttetDLRQQLETAKNEKRVATKEL 2071
Cdd:TIGR02168  309 ERLANL---ERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELE-------SLEAELEELEAELEELESRL 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2072 EDLKrrlAQLENERRNSSQlsdgwkkekitLLKKIELLENEKRRTDAairetalQREAIEKSLNAMERENKELYKNCAQL 2151
Cdd:TIGR02168  375 EELE---EQLETLRSKVAQ-----------LELQIASLNNEIERLEA-------RLERLEDRRERLQQEIEELLKKLEEA 433

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529   2152 QQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVI---ENRERTHRNRIKQLEDQ 2212
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALdaaERELAQLQARLDSLERL 497
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
791-1410 1.66e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 73.15  E-value: 1.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   791 DIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHlaEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGR 870
Cdd:PRK02224  173 DARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGL--ESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   871 QDLEKNGArnndELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDI 950
Cdd:PRK02224  251 EELETLEA----EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   951 LNQKLKLDGDVQALKETIRKLENELEKLRNENKELvgKEARARdaanqqlsranlLNKELEDTKQDLKHSTDVNKQLEQD 1030
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEEL--REEAAE------------LESELEEAREAVEDRREEIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1031 IRDLKERLANigkggrisrdstTGTDGGAFGDRSS--VADPSRTRGAAGSTvfvpaaediesrgggEIDIPSSGDVIhgR 1108
Cdd:PRK02224  393 IEELRERFGD------------APVDLGNAEDFLEelREERDELREREAEL---------------EATLRTARERV--E 443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1109 DGRDGRDAGNRGT-----------HTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWK--RELERLENEKDDLER 1175
Cdd:PRK02224  444 EAEALLEAGKCPEcgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEaeDRIERLEERREDLEE 523

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1176 RIRELEDELsqigrgndktenditELKRKHAAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDL------R 1249
Cdd:PRK02224  524 LIAERRETI---------------EEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLaelkerI 588

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1250 DKLNNLEKQLADSLNRENELE--REKRdydekinslygqnqKIKDEWDDFRNDADKEIQKWKTDAytvrsEAKALETTNT 1327
Cdd:PRK02224  589 ESLERIRTLLAAIADAEDEIErlREKR--------------EALAELNDERRERLAEKRERKREL-----EAEFDEARIE 649

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1328 ALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKgNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWR 1407
Cdd:PRK02224  650 EAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE-ELRERREALENRVEALEALYDEAEELESMYGDLR 728


                  ...
gi 25151529  1408 GEL 1410
Cdd:PRK02224  729 AEL 731
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1732-2220 1.72e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1732 IANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAK----- 1806
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelq 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1807 ----------TLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQ-- 1874
Cdd:TIGR02168  440 aeleeleeelEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGls 519

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1875 ------WDSSRFQ------LETKMRES-----DSDTNKYQLQIASFESER----------QILTEKIKELDGALRLSDSK 1927
Cdd:TIGR02168  520 gilgvlSELISVDegyeaaIEAALGGRlqavvVENLNAAKKAIAFLKQNElgrvtflpldSIKGTEIQGNDREILKNIEG 599

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1928 VQDMKDDTDKLRRDLTKAES-------VENELRKTIDIQSKTSHEYQLLKDQ--------------------LLNTQNEL 1980
Cdd:TIGR02168  600 FLGVAKDLVKFDPKLRKALSyllggvlVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvitggsaktnssILERRREI 679

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1981 NGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETA 2060
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2061 KNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERE 2140
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2141 NKELykncaqlqqqiaQLEMENGNRILELTNKQREEQ-------ERQLIRMRQEKGQIEKVIENRE----------RTHR 2203
Cdd:TIGR02168  840 LEDL------------EEQIEELSEDIESLAAEIEELeelieelESELEALLNERASLEEALALLRseleelseelRELE 907

                          570
                   ....*....|....*..
gi 25151529   2204 NRIKQLEDQIAILRDQL 2220
Cdd:TIGR02168  908 SKRSELRRELEELREKL 924
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 617-1523 1.93e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.23  E-value: 1.93e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    617 QQLERKLKIAESQVKEFLNKFENADEARrrlDKQFADAKREISNLQKSVDEA--ERNSRrTDDKLRASEAErvaaEKARK 694
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELH---EKQKFYLRQSVIDLQTKLQEMqmERDAM-ADIRRRESQSQ----EDLRN 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    695 FLEDELAKLQAS------FQKSSTDDARKLRDEMDEHTNSIQEEFKTRID---------------------ELNRRVENL 747
Cdd:pfam15921  146 QLQNTVHELEAAkclkedMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDfeeasgkkiyehdsmstmhfrSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    748 LRENNR----LKSEVNPLKDKYRDLENEynsTQRRIEEKETQirYSDDIRRNIQK---DLDDLREKYDRVHTDNEKILGE 820
Cdd:pfam15921  226 LRELDTeisyLKGRIFPVEDQLEALKSE---SQNKIELLLQQ--HQDRIEQLISEhevEITGLTEKASSARSQANSIQSQ 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    821 LEHAQKAA---------HLAE------QQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELD 885
Cdd:pfam15921  301 LEIIQEQArnqnsmymrQLSDlestvsQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    886 KLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKL---------- 955
Cdd:pfam15921  381 KLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknesl 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    956 ----KLDGDVQALKETIRKLENEL--EKLRNENKE---------LVGKEaRARDAANQQL----SRANLLNKELEDTKQD 1016
Cdd:pfam15921  461 ekvsSLTAQLESTKEMLRKVVEELtaKKMTLESSErtvsdltasLQEKE-RAIEATNAEItklrSRVDLKLQELQHLKNE 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1017 LKHSTDVNKQLEQdirdLKERLANIGKGGRISRdsttgtdggafgdrssvadpsrtrgaagstvfvpaaEDIESrgggei 1096
Cdd:pfam15921  540 GDHLRNVQTECEA----LKLQMAEKDKVIEILR------------------------------------QQIEN------ 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1097 dipssgdvIHGRDGRDGRDAGNRgthtitntkerieRIEKNILDryhddelvehkiREVNDRwKRELERLENEKDDLERR 1176
Cdd:pfam15921  574 --------MTQLVGQHGRTAGAM-------------QVEKAQLE------------KEINDR-RLELQEFKILKDKKDAK 619

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1177 IRELEDELSQIgrgndktenditelkrkhaaEIDKLKsdisalhdkhlsdLDDEKEQYGKAVENLKSVEDDLRDKLNNLE 1256
Cdd:pfam15921  620 IRELEARVSDL--------------------ELEKVK-------------LVNAGSERLRAVKDIKQERDQLLNEVKTSR 666

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1257 KQLaDSLNRENELerEKRDYDEKINSLYGQNQKIKdewddfrndadKEIQKWKTDAYTVRSEAKALETTNT-ALKAQLQa 1335
Cdd:pfam15921  667 NEL-NSLSEDYEV--LKRNFRNKSEEMETTTNKLK-----------MQLKSAQSELEQTRNTLKSMEGSDGhAMKVAMG- 731

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1336 andridhLTKTVNDHTSKVRDLTSQVRHLEDELAdtkgNLVQKEMDLESTQNRlrsLEDQHSTLQSDANKWRGELDAALR 1415
Cdd:pfam15921  732 -------MQKQITAKRGQIDALQSKIQFLEEAMT----NANKEKHFLKEEKNK---LSQELSTVATEKNKMAGELEVLRS 797

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1416 ENDILKSNNTNMETDLTRLKNRLKSAEDALKE-----LKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQfdTKLTKL 1490
Cdd:pfam15921  798 QERRLKEKVANMEVALDKASLQFAECQDIIQRqeqesVRLKLQHTLDVKELQGPGYTSNSSMKPRLLQPASF--TRTHSN 875

                          970       980       990
                   ....*....|....*....|....*....|....*..
gi 25151529   1491 RNELQDTNDKLITSDTERNALRN----ELQKLSQELK 1523
Cdd:pfam15921  876 VPSSQSTASFLSHHSRKTNALKEdptrDLKQLLQELR 912
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1788-2134 3.12e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 3.12e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1788 LQDAEEERRALESRLQSAKTLLrsqEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRS 1867
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLII---DEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1868 LRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQI-LTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAE 1946
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1947 SVENELRKTIDIQSKTSHEYQLLKDQLL----NTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQL 2022
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTeeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2023 QDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITL 2102
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350
                   ....*....|....*....|....*....|..
gi 25151529   2103 LKKIELLENEKRRTDAAIRETALQREAIEKSL 2134
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASI 520
PRK01156 PRK01156
chromosome segregation protein; Provisional
 750-1405 3.80e-12

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 72.24  E-value: 3.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   750 ENNRLKSEVNPLKDKYRDLENEYNStqrrIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAH 829
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEISN----IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYN 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   830 LAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLrrhnDELD 909
Cdd:PRK01156  236 NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDI----ENKK 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   910 TTIKGHQGKITHLEnELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKE 989
Cdd:PRK01156  312 QILSNIDAEINKYH-AIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMS 390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   990 ARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRI-SRDSTTGTDGGAFGDRSSvad 1068
Cdd:PRK01156  391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMlNGQSVCPVCGTTLGEEKS--- 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1069 psrtrgaagstvfvpaaediesrgggeidipssgdvihgrdgrdgRDAGNRGTHTITNTKERIERIEKNILDRyhdDELV 1148
Cdd:PRK01156  468 ---------------------------------------------NHIINHYNEKKSRLEEKIREIEIEVKDI---DEKI 499

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1149 EHKIREVNDRWKRELERLENEKDDLERRIRELEDElsqigrgndktENDITELKRKHaaeiDKLKSDISALHDKHLSDLD 1228
Cdd:PRK01156  500 VDLKKRKEYLESEEINKSINEYNKIESARADLEDI-----------KIKINELKDKH----DKYEEIKNRYKSLKLEDLD 564

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1229 DEKEQYGKAVENLKSVE-DDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGqnqKIKDEWDDFRNDAdKEIQK 1307
Cdd:PRK01156  565 SKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIR---EIENEANNLNNKY-NEIQE 640

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1308 WKTDAYTVRSEAKalettntalkaQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQN 1387
Cdd:PRK01156  641 NKILIEKLRGKID-----------NYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRT 709

                         650
                  ....*....|....*...
gi 25151529  1388 RLRSLEDQHSTLQSDANK 1405
Cdd:PRK01156  710 RINELSDRINDINETLES 727
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 764-1610 4.22e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    764 KYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLrEKYDRVHTDNEKILGELEHAQKAAHlaEQQLKEIKIQRD 843
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELLKEKEAL--ERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    844 DYQKQKDEHARHLFDIRHKLET-EIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHL 922
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEiEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    923 ENELHSRSGEIEKLNDLNQRLQKEKQdilnqklkldgdvqALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSR 1002
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRD--------------KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1003 ANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIgkggrisrdsttgtdggafgdrssvadpsrtrgAAGSTVFV 1082
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGI---------------------------------EAKINELE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1083 PAAEDIesrgggeidipssgdvihgrdgrdgrdagnrgthtitntKERIERIEKNIldryhddelveHKIREVNDRWKRE 1162
Cdd:TIGR02169  441 EEKEDK---------------------------------------ALEIKKQEWKL-----------EQLAADLSKYEQE 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1163 LERLENEKDDLERRIRELEDELSQIgrgnDKTENDITELKRKHAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVE--- 1239
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEA----EAQARASEERVRGGRAVEEVLKASIQGVHGT-VAQLGSVGERYATAIEvaa 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1240 ----NLKSVEDD---------LRDKlnNLEKQLADSLNRENELEREKR---------------DYDEKINSLYGQN---- 1287
Cdd:TIGR02169  546 gnrlNNVVVEDDavakeaielLKRR--KAGRATFLPLNKMRDERRDLSilsedgvigfavdlvEFDPKYEPAFKYVfgdt 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1288 ------QKIKDEWDDFRN-DADKEIQKwKTDAYTVRSEA-KALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTS 1359
Cdd:TIGR02169  624 lvvediEAARRLMGKYRMvTLEGELFE-KSGAMTGGSRApRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN 702

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1360 QVRHLEDELADTKGNLVQKEMDLEStqnrlrsledqhstLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLK 1439
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQ--------------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIE 768

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1440 SAEDALKELKNSLshAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNalrnELQKLS 1519
Cdd:TIGR02169  769 ELEEDLHKLEEAL--NDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ----ELQEQR 842

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1520 QELKFGNEQIQRKSDEYQTTIDDLAhshrvsedsrlnalQELEARKYEINDLTSRL-------DSTEQRLATLQQDYIKA 1592
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELE--------------EELEELEAALRDLESRLgdlkkerDELEAQLRELERKIEEL 908

                          890
                   ....*....|....*...
gi 25151529   1593 DSERDILSDALRRFQSSA 1610
Cdd:TIGR02169  909 EAQIEKKRKRLSELKAKL 926
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1740-2144 4.67e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 71.99  E-value: 4.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1740 QSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQR 1819
Cdd:PRK02224  310 EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1820 DEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQwdSSRFQLETKMRESDSD------- 1892
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE--AEALLEAGKCPECGQPvegsphv 467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1893 --TNKYQLQIASFESERQILTEKIKELDGALrlsdSKVQDMKDDTDKLRRDLTKAESVEnelrKTIDIQSKTSHEYQLLK 1970
Cdd:PRK02224  468 etIEEDRERVEELEAELEDLEEEVEEVEERL----ERAEDLVEAEDRIERLEERREDLE----ELIAERRETIEEKRERA 539

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1971 DQLlntqnelngaNNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDrflsvekvVNTMRTTE 2050
Cdd:PRK02224  540 EEL----------RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAI 601

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2051 TDLRQQLETaKNEKRVATKELEDLKRRLAQLENERRnsSQLSDGWKKEKITLLK-KIELLENEKRRTDAAIRETALQREA 2129
Cdd:PRK02224  602 ADAEDEIER-LREKREALAELNDERRERLAEKRERK--RELEAEFDEARIEEAReDKERAEEYLEQVEEKLDELREERDD 678

                         410
                  ....*....|....*
gi 25151529  2130 IEKSLNAMERENKEL 2144
Cdd:PRK02224  679 LQAEIGAVENELEEL 693
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1731-2199 5.08e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 5.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTI------NQKETRYRNIEDNLQDAEEERRALESRLQS 1804
Cdd:PRK03918  253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIklsefyEEYLDELREIEKRLSRLEEEINGIEERIKE 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1805 AKTLLRSQEEALKQRDE-ERRQMKSKMVAAELQ-ARGKEAQLRHLNEQLKNLrtDLDNAHTDIRSLRDKEEQWDSSRFQL 1882
Cdd:PRK03918  333 LEEKEERLEELKKKLKElEKRLEELEERHELYEeAKAKKEELERLKKRLTGL--TPEKLEKELEELEKAKEEIEEEISKI 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1883 ETKMRESDSDTNKYQLQIASFESERQI-------LTEKIKEldGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKT 1955
Cdd:PRK03918  411 TARIGELKKEIKELKKAIEELKKAKGKcpvcgreLTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1956 IDIQSKTSHEYQLLkDQLLNTQNELNGANNRKQQLENEllnvrsEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEdr 2035
Cdd:PRK03918  489 LKKESELIKLKELA-EQLKELEEKLKKYNLEELEKKAE------EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA-- 559

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2036 flSVEKVVNTMRTTETDLRQQLEtaknekRVATKELEDLKRRLAQLENERRNSSQLSDGwKKEKITLLKKIELLENEKRR 2115
Cdd:PRK03918  560 --ELEKKLDELEEELAELLKELE------ELGFESVEELEERLKELEPFYNEYLELKDA-EKELEREEKELKKLEEELDK 630

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2116 TDAAIRETALQREAIEKSLNAMERE-NKELYKNcAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKV 2194
Cdd:PRK03918  631 AFEELAETEKRLEELRKELEELEKKySEEEYEE-LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709


                  ....*
gi 25151529  2195 IENRE 2199
Cdd:PRK03918  710 KKELE 714
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
858-1468 5.72e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 5.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   858 DIRHKLETEIKGRQDLE---KNGARNNDELDKLRQTISDY---ESQI-NLLRRHNDELDTTIKghqgKITHLENELHSRS 930
Cdd:PRK03918  145 ESREKVVRQILGLDDYEnayKNLGEVIKEIKRRIERLEKFikrTENIeELIKEKEKELEEVLR----EINEISSELPELR 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   931 GEIEKLNDLNQRLQKEKQDILN---QKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLsRANLLN 1007
Cdd:PRK03918  221 EELEKLEKEVKELEELKEEIEElekELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAE-EYIKLS 299

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1008 KELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKggrisrdsttgtdggafgdrssvadpsrtrgaagstvfvpAAED 1087
Cdd:PRK03918  300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE----------------------------------------KEER 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1088 IESRGGGEIDIPSSGDVIHGRdgrdgrdagNRGTHTITNTKERIERIEKNILDRyhDDELVEHKIREVNDRWK---RELE 1164
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEER---------HELYEEAKAKKEELERLKKRLTGL--TPEKLEKELEELEKAKEeieEEIS 408

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1165 RLENEKDDLERRIRELEDELSQIGRGNDK--------TENDITELKRKHAAEIDKLKSDISALHDKhLSDLDDEKEQYGK 1236
Cdd:PRK03918  409 KITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEK-ERKLRKELRELEK 487

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1237 AVENLK--SVEDDLRDKLNNLEKQLaDSLNREnELEREKRDYD---EKINSLYGQNQKIKDEWddfrndadKEIQKWKTD 1311
Cdd:PRK03918  488 VLKKESelIKLKELAEQLKELEEKL-KKYNLE-ELEKKAEEYEklkEKLIKLKGEIKSLKKEL--------EKLEELKKK 557

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1312 AYTVRSEAKALETTNTALKAQL--------QAANDRIDHLTKTVNDHTSkVRDLTSQVRHLEDELADTKGNLVQKEMDLE 1383
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELeelgfesvEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELA 636

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1384 STQNRLRSLEDQHSTLQSDANKwrgeldaalRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQ 1463
Cdd:PRK03918  637 ETEKRLEELRKELEELEKKYSE---------EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707


                  ....*
gi 25151529  1464 NAFRE 1468
Cdd:PRK03918  708 KAKKE 712
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
609-1257 6.28e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.25  E-value: 6.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   609 FRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKsvdeaerNSRRTDDKLRASEAERVA 688
Cdd:PRK03918  160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISS-------ELPELREELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   689 AEKARKFLEdELAKLQASFQKSstddARKLRDEMDEHTNSIqEEFKTRIDELNRRVENLlrennrlkSEVNPLKDKYRDL 768
Cdd:PRK03918  233 LEELKEEIE-ELEKELESLEGS----KRKLEEKIRELEERI-EELKKEIEELEEKVKEL--------KELKEKAEEYIKL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   769 E---NEYNSTQRRIEEKETqiRYSDDIrRNIQKDLDDLREKYDRVhtdnEKILGELEHAQ------KAAHLAEQQLKEIK 839
Cdd:PRK03918  299 SefyEEYLDELREIEKRLS--RLEEEI-NGIEERIKELEEKEERL----EELKKKLKELEkrleelEERHELYEEAKAKK 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   840 IQRDDYQKQKDEhaRHLFDIRHKLETEIKGRQDLEKngarnndELDKLRQTISDYESQINLLRRHNDELdttiKGHQGKI 919
Cdd:PRK03918  372 EELERLKKRLTG--LTPEKLEKELEELEKAKEEIEE-------EISKITARIGELKKEIKELKKAIEEL----KKAKGKC 438

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   920 ---------THLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETI--RKLENELEKLRNENKELVGK 988
Cdd:PRK03918  439 pvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIklKELAEQLKELEEKLKKYNLE 518

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   989 EARARDAANQQL-SRANLLNKELEDTKQDLKHSTDVNKQ---LEQDIRDLKERLANIGKggrisrdsttgtdggafgdrs 1064
Cdd:PRK03918  519 ELEKKAEEYEKLkEKLIKLKGEIKSLKKELEKLEELKKKlaeLEKKLDELEEELAELLK--------------------- 577

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1065 svadpsrtrgaagstvfvpaaediesrgggeidipssgdvihgrdgrdgrDAGNRGTHTITNTKERIERIEKnILDRYhd 1144
Cdd:PRK03918  578 --------------------------------------------------ELEELGFESVEELEERLKELEP-FYNEY-- 604

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1145 delveHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIgrgnDKTENDITELKRKHAAEIDKLKSDISALHDKHL 1224
Cdd:PRK03918  605 -----LELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL----EELRKELEELEKKYSEEEYEELREEYLELSREL 675

                         650       660       670
                  ....*....|....*....|....*....|...
gi 25151529  1225 SDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEK 1257
Cdd:PRK03918  676 AGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 545-1283 7.88e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  545 LEAELRRNREKLnEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSLSpgktplppsEALRAVRNTFRNKDNDIQQLERKLK 624
Cdd:COG1196  194 ILGELERQLEPL-ERQAEKAERYRELKEELKELEAELLLLKLRELE---------AELEELEAELEELEAELEELEAELA 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  625 IAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQ 704
Cdd:COG1196  264 ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  705 ASfqksstddarklrdemdehtnsiQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKET 784
Cdd:COG1196  344 EE-----------------------LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  785 QIrysddirRNIQKDLDDLREkydrvhtdnekilgELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLE 864
Cdd:COG1196  401 QL-------EELEEAEEALLE--------------RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  865 TEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELdttikghqgkithlenELHSRSGEIEKLNDLNQRLQ 944
Cdd:COG1196  460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY----------------EGFLEGVKAALLLAGLRGLA 523

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  945 KEKQDILnqklkldGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANqQLSRANLLnkELEDTKQDLKHSTDVN 1024
Cdd:COG1196  524 GAVAVLI-------GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA-KAGRATFL--PLDKIRARAALAAALA 593

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1025 KQLEQDIRDLKERLAnigkggrISRDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDV 1104
Cdd:COG1196  594 RGAIGAAVDLVASDL-------READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1105 IHGRDGRDGRDAGNRGTHTITNTKERIERIEKNILDRYHDDELVEHKIREV--NDRWKRELERLENEKDDLERRIRELED 1182
Cdd:COG1196  667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLeeELEEEALEEQLEAEREELLEELLEEEE 746

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1183 ELSQIGRGNDKTENDITELKRkhaaEIDKLKSDISALhdkhlsdlddekeqyGkAVeNLKSVE--DDLRDKLNNLEKQLA 1260
Cdd:COG1196  747 LLEEEALEELPEPPDLEELER----ELERLEREIEAL---------------G-PV-NLLAIEeyEELEERYDFLSEQRE 805

                        730       740
                 ....*....|....*....|...
gi 25151529 1261 DslnreneLEREKRDYDEKINSL 1283
Cdd:COG1196  806 D-------LEEARETLEEAIEEI 821
PTZ00121 PTZ00121
MAEBL; Provisional
 325-1046 1.25e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 70.94  E-value: 1.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   325 IARLDEERRRSDEYRmQWENERQKSLSLEDENDRLRREFERYANDSKDKEKTFINRERNLAQYLSDEQRKMLDLWTELQR 404
Cdd:PTZ00121 1156 IARKAEDARKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE 1234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   405 VRKQFSDLKTHTEEDLDKQKAEFTRAiRNVNNISRNAAFSAgagdglglygledggdvnrttnnYEKVFIETIKRMNGTG 484
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEIRKFEEA-RMAHFARRQAAIKA-----------------------EEARKADELKKAEEKK 1290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   485 GAGSASSAdllEELRKIRGGGSSEGDAELHKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGAlK 564
Cdd:PTZ00121 1291 KADEAKKA---EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-A 1366

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   565 KLHEMAQDSEKnvdgtvsiKRTRSLSPGKTPLPPSEALRAVRNTFRNKDNDIQQLERKLKIAEsQVKEFLNKFENADEAR 644
Cdd:PTZ00121 1367 EAAEKKKEEAK--------KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD-EAKKKAEEKKKADEAK 1437

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   645 RRldkqfADAKREISNLQKSVDE---AERNSRRTDDKLRASEAERVAAEKARKfledELAKLQASFQKSSTDDARKLRDE 721
Cdd:PTZ00121 1438 KK-----AEEAKKADEAKKKAEEakkAEEAKKKAEEAKKADEAKKKAEEAKKA----DEAKKKAEEAKKKADEAKKAAEA 1508

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   722 MDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQirysdDIRRNIQKDLD 801
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA-----EEDKNMALRKA 1583

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   802 DLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRddyQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNN 881
Cdd:PTZ00121 1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE---LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   882 DELDKLRQTISDYESQINLLRRHNDELDTTikghqgkithlENELHSRSGEIEKLNDLNQRLQKEKQDIlnQKLKLDGDV 961
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKA-----------AEALKKEAEEAKKAEELKKKEAEEKKKA--EELKKAEEE 1727

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   962 QALK-ETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQD--IRDLKERL 1038
Cdd:PTZ00121 1728 NKIKaEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDkkIKDIFDNF 1807


                  ....*...
gi 25151529  1039 ANIGKGGR 1046
Cdd:PTZ00121 1808 ANIIEGGK 1815
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1900-2249 1.30e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1900 IASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDI-QSKTSHEYQLLKDQLLNTQN 1978
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYeGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1979 ELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELqrqlqdANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLE 2058
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL------GEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2059 TAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAME 2138
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2139 RENKELYKNCAQLQQQIAQLEMENGN----------RILEL----TNKQRE--EQERQLIRMRQEKGQIEKVIENRERTH 2202
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADlnaaiagieaKINELeeekEDKALEikKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529   2203 R---NRIKQLEDQIAILRDQLDGERRRRREYVDRSMVndigrLGSNVLGI 2249
Cdd:TIGR02169  479 DrveKELSKLQRELAEAEAQARASEERVRGGRAVEEV-----LKASIQGV 523
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 323-1037 2.14e-11

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 69.69  E-value: 2.14e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    323 EMIARLDEERRRSDEYRMQWENERQKSLSLEDENDRLRREFERYANDSKD----KEKTFINRERNLAQYLSDEQRKMLDL 398
Cdd:TIGR00606  238 EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSElelkMEKVFQGTDEQLNDLYHNHQRTVREK 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    399 WTELQRVRKQFSDLKTHTEEdLDKQKAEFT--------RAIRNVNNISRNAAFSAGAGDGLGLYGLEDGGDVNRTTNNYE 470
Cdd:TIGR00606  318 ERELVDCQRELEKLNKERRL-LNQEKTELLveqgrlqlQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFH 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    471 KVFIEtikRMNGTGGAGSASSADLLEELR-------KIRGGGSSEGDA-ELHKELMTKYEESIERNIELESRGDDSQRKI 542
Cdd:TIGR00606  397 TLVIE---RQEDEAKTAAQLCADLQSKERlkqeqadEIRDEKKGLGRTiELKKEILEKKQEELKFVIKELQQLEGSSDRI 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    543 AELEAELRRNREKL--------------------NEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSLSPGKTplppSEAL 602
Cdd:TIGR00606  474 LELDQELRKAERELskaeknsltetlkkevkslqNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKM----DKDE 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    603 RAVRNTFRNKDNDIQQLER--KLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLR 680
Cdd:TIGR00606  550 QIRKIKSRHSDELTSLLGYfpNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLF 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    681 ---ASEAERVAAEKARKFLEDELAKLQASFQKSSTDDA--RKLRDEMDEHTNSIQEEFKTR--IDELNRRVENLLREnnr 753
Cdd:TIGR00606  630 dvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQfiTQLTDENQSCCPVCQRVFQTEaeLQEFISDLQSKLRL--- 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    754 lksevnpLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQK------- 826
Cdd:TIGR00606  707 -------APDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETllgtimp 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    827 AAHLAEQQLKEIKIQRDDYQKQKDEHARHlfdirhkleteikGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHND 906
Cdd:TIGR00606  780 EEESAKVCLTDVTIMERFQMELKDVERKI-------------AQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIE 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    907 ELDTTIKGHQGKITHLE---NELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENK 983
Cdd:TIGR00606  847 LNRKLIQDQQEQIQHLKsktNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKE 926

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 25151529    984 ELVGKEARARDAANQqlsranllnkELEDTKQDLKHSTDVNKQLEQDIRDLKER 1037
Cdd:TIGR00606  927 ELISSKETSNKKAQD----------KVNDIKEKVKNIHGYMKDIENKIQDGKDD 970
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1739-2220 2.17e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 2.17e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1739 LQSLLNKIEKLEMERNELRDTLARMKKKTTethttinQKETRYRNIEDNLQDAEEERRALESRLQSAKtllrsqeEALKQ 1818
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLQEELQ-------RLSEELADLNAAIAGIEAKINELEEEKEDKA-------LEIKK 452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1819 RDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRdkEEQWDSSRFQLETK---------MRES 1889
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE--ERVRGGRAVEEVLKasiqgvhgtVAQL 530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1890 DSDTNKYQLQIASFESER----------------QILteKIKELDGALRLSDSKVQDMKDDTDKLRR------------- 1940
Cdd:TIGR02169  531 GSVGERYATAIEVAAGNRlnnvvveddavakeaiELL--KRRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdlvef 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1941 DLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNEL---NGA-------------------------NNRKQQLEN 1992
Cdd:TIGR02169  609 DPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELfekSGAmtggsraprggilfsrsepaelqrlRERLEGLKR 688

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1993 ELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELE 2072
Cdd:TIGR02169  689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIE 768

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2073 DLKRRLAQLENERRNSSQLSDGWKKEKITllKKIELLENEKRRTDAAIRET--ALQREAIEKSLNAMERENKELYKNCAQ 2150
Cdd:TIGR02169  769 ELEEDLHKLEEALNDLEARLSHSRIPEIQ--AELSKLEEEVSRIEARLREIeqKLNRLTLEKEYLEKEIQELQEQRIDLK 846

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529   2151 LQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRE---RTHRNRIKQLEDQIAILRDQL 2220
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRL 919
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1124-1588 2.18e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.71  E-value: 2.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1124 ITNTKERIERIEKNILDRYHDDELVEHKIREVNDRwKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKR 1203
Cdd:PRK03918  202 LEEVLREINEISSELPELREELEKLEKEVKELEEL-KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEE 280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1204 KhAAEIDKLKSD------ISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRD------KLNNLEKQLADSLNRENELER 1271
Cdd:PRK03918  281 K-VKELKELKEKaeeyikLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEleekeeRLEELKKKLKELEKRLEELEE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1272 EKRDYdEKINSLYGQNQKIKDEWDDFR-NDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKT---- 1346
Cdd:PRK03918  360 RHELY-EEAKAKKEELERLKKRLTGLTpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkc 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1347 ---------------VNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDL--ESTQNRLRSLEDQHSTLQSDANKWRGE 1409
Cdd:PRK03918  439 pvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKYNLE 518

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1410 -LDAALRENDILKSNNTNMETDLTRLKNRLKSAED---ALKELKNSLSHAKTEKERLQNAFREKT-KQADHLNQLASQFD 1484
Cdd:PRK03918  519 eLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEElkkKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1485 T------KLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELkfgnEQIQRKSDEYQTTIDDlaHSHRVSEDSRLNAL 1558
Cdd:PRK03918  599 PfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL----EELRKELEELEKKYSE--EEYEELREEYLELS 672

                         490       500       510
                  ....*....|....*....|....*....|
gi 25151529  1559 QELEARKYEINDLTSRLDSTEQRLATLQQD 1588
Cdd:PRK03918  673 RELAGLRAELEELEKRREEIKKTLEKLKEE 702
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1172-1601 2.22e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 69.68  E-value: 2.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1172 DLERRIRELEDEL-SQIgrgNDKTENDITELKRKHAAEIDKLKSDISALHDKHlsdlDDEKEQYGKAVENLKSVEDDlRD 1250
Cdd:PRK02224  180 RVLSDQRGSLDQLkAQI---EEKEEKDLHERLNGLESELAELDEEIERYEEQR----EQARETRDEADEVLEEHEER-RE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1251 KLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEiqkwKTDAYTVRSEAKALETTNTAL- 1329
Cdd:PRK02224  252 ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLD----DADAEAVEARREELEDRDEELr 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1330 ------KAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDA 1403
Cdd:PRK02224  328 drleecRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1404 NKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELK--------------NSLSHAKTEKERL------- 1462
Cdd:PRK02224  408 GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvETIEEDRERVEELeaeledl 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1463 ---QNAFREKTKQADHLNQLASQFDTKLTKLRN--ELQDTNDKLITSDTERNA-LRNELQKLSQELKFGNEQIQRKSDEY 1536
Cdd:PRK02224  488 eeeVEEVEERLERAEDLVEAEDRIERLEERREDleELIAERRETIEEKRERAEeLRERAAELEAEAEEKREAAAEAEEEA 567

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529  1537 QTTIDDLA--HSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQdyiKADSERDILSD 1601
Cdd:PRK02224  568 EEAREEVAelNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAE---LNDERRERLAE 631
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1936-2221 2.47e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1936 DKLRRDLTKAESVENELRK---TIDIQSKTSHEYQLLKDQLLNTQNELNGanNRKQQLENELLNVRSEVRDYKQRVHDVN 2012
Cdd:TIGR02168  182 ERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2013 NRVSELQRQLQDANTEKNRVEDRFLSVEKVVNtmrttetDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLS 2092
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELY-------ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2093 DGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEME---NGNRILEL 2169
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEierLEARLERL 412

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   2170 T-NKQREEQERQLIRMRQEKGQIEKVIEN-------------RERTHRNRIKQLEDQIAILRDQLD 2221
Cdd:TIGR02168  413 EdRRERLQQEIEELLKKLEEAELKELQAEleeleeeleelqeELERLEEALEELREELEEAEQALD 478
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 515-1028 2.58e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.38  E-value: 2.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    515 KELMTKYEESIErniELESrgddsQRKIAELE-AELRRNREKLNEAQGALK-KLHEMAQDSEKNvDGTVSIKRTRSLSPG 592
Cdd:pfam15921  334 REAKRMYEDKIE---ELEK-----QLVLANSElTEARTERDQFSQESGNLDdQLQKLLADLHKR-EKELSLEKEQNKRLW 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    593 KTPLPPSEALRAVRNTFRNKDNDIQQLERKLKIAES----QVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEA 668
Cdd:pfam15921  405 DRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEEL 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    669 E------RNSRRT--------DDKLRASEAERVAAEKARKFLEDELAKLQasFQKSSTDDARKLRDEMDEHTNSIQEEFK 734
Cdd:pfam15921  485 TakkmtlESSERTvsdltaslQEKERAIEATNAEITKLRSRVDLKLQELQ--HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    735 TrIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNStqRRIEEKETQI--RYSDDIRRNIQKDLDDLR-EKYDRVH 811
Cdd:pfam15921  563 V-IEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND--RRLELQEFKIlkDKKDAKIRELEARVSDLElEKVKLVN 639

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    812 TDNEKILGELEHAQKAahlaEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTI 891
Cdd:pfam15921  640 AGSERLRAVKDIKQER----DQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTL 715

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    892 SDYESQinllrrhNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKL 971
Cdd:pfam15921  716 KSMEGS-------DGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529    972 ENELEKLRNENKELVGKEAR---ARDAANQQLSRAN--LLNKELEDTKQDLKHSTDVnKQLE 1028
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANmevALDKASLQFAECQdiIQRQEQESVRLKLQHTLDV-KELQ 849
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
835-1345 3.56e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 68.64  E-value: 3.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  835 LKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKG 914
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  915 HQgkithLENELHSRSgeiEKLNDLNQRLQKEKQDILnqklkldgDVQALKETIRKLENELEKLRNE-NKELVGKEARAR 993
Cdd:COG4717  128 LP-----LYQELEALE---AELAELPERLEELEERLE--------ELRELEEELEELEAELAELQEElEELLEQLSLATE 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  994 DAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGA----FGDRSSVADP 1069
Cdd:COG4717  192 EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAllalLGLGGSLLSL 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1070 SRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRdgrdagnrgthtitntkERIERIE-KNILDRYHDDELV 1148
Cdd:COG4717  272 ILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL-----------------EELEEEElEELLAALGLPPDL 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1149 EHKIREVNDRWKRELERLENEKDDLERRIR--ELEDELSQIGRGNDKTENDITELKRKHAAEIDKLKSDISALHDKhLSD 1226
Cdd:COG4717  335 SPEELLELLDRIEELQELLREAEELEEELQleELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQ-LEE 413

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1227 LDDEKEQYGKAVEnlksvEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQN--QKIKDEWDDFRNDADKE 1304
Cdd:COG4717  414 LLGELEELLEALD-----EEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGelAELLQELEELKAELREL 488

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 25151529 1305 IQKWKTDAYTVRSEAKALE-TTNTALKAQLQAANDRIDHLTK 1345
Cdd:COG4717  489 AEEWAALKLALELLEEAREeYREERLPPVLERASEYFSRLTD 530
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 614-1586 4.86e-11

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 68.92  E-value: 4.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    614 NDIQQLERKLKIAESQVKEFLNKFEnadEARRRLDKQFADAKREISNLQKSVDEAERNSrrTDDKLRASEAERVAAEKAR 693
Cdd:TIGR01612 1111 DEINKIKDDIKNLDQKIDHHIKALE---EIKKKSENYIDEIKAQINDLEDVADKAISND--DPEEIEKKIENIVTKIDKK 1185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    694 KFLEDELAKLQASFQKSSTDDA--RKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENE 771
Cdd:TIGR01612 1186 KNIYDEIKKLLNEIAEIEKDKTslEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENE 1265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    772 YNSTQRRIEEKET-QIRYSDD-----IRRNIQKDLDDLREKYDRVHTDNEK------ILGELE----HAQKAAHLAEQQL 835
Cdd:TIGR01612 1266 MGIEMDIKAEMETfNISHDDDkdhhiISKKHDENISDIREKSLKIIEDFSEesdindIKKELQknllDAQKHNSDINLYL 1345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    836 KEIKiqrDDYQKQKDEHARHLFDIRHKLETEIkgrqdlEKNGARNNDELDKLRQTISDYESQINlLRRHNDELDTTIKGH 915
Cdd:TIGR01612 1346 NEIA---NIYNILKLNKIKKIIDEVKEYTKEI------EENNKNIKDELDKSEKLIKKIKDDIN-LEECKSKIESTLDDK 1415

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    916 Q-----GKITHLENELHSRSG---------------------EIEKLNDLNQRLQKEKQDilNQKLKLDGDVQALKETIR 969
Cdd:TIGR01612 1416 DideciKKIKELKNHILSEESnidtyfknadennenvlllfkNIEMADNKSQHILKIKKD--NATNDHDFNINELKEHID 1493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    970 KlENELEKLRNENKELVGKEARARDAANQQLSRanLLNKELE-DTKQDLKHSTDVNKQLEQDIRDLKERL-----ANIGK 1043
Cdd:TIGR01612 1494 K-SKGCKDEADKNAKAIEKNKELFEQYKKDVTE--LLNKYSAlAIKNKFAKTKKDSEIIIKEIKDAHKKFileaeKSEQK 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1044 GGRISRDSTTGTDGGAFGDRSSVAdpsrtrgaagstvfvpaaediesrgggEIDIPSSGDVIHGRdgrdgrdagnrgTHT 1123
Cdd:TIGR01612 1571 IKEIKKEKFRIEDDAAKNDKSNKA---------------------------AIDIQLSLENFENK------------FLK 1611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1124 ITNTKERI-------ERIEKNILDRYHDDELVEHKIREVNDRWKRE-LERLENEKDDLERRIRELEDELSQIgrgnDKTE 1195
Cdd:TIGR01612 1612 ISDIKKKIndclketESIEKKISSFSIDSQDTELKENGDNLNSLQEfLESLKDQKKNIEDKKKELDELDSEI----EKIE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1196 NDITELKRKHAAEI-DKLKSDISALHDKhlsdLDDEKEQYGKAVENLKSVED-------DLRDKLNNLEKQLADSLNREN 1267
Cdd:TIGR01612 1688 IDVDQHKKNYEIGIiEKIKEIAIANKEE----IESIKELIEPTIENLISSFNtndlegiDPNEKLEEYNTEIGDIYEEFI 1763

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1268 ELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQ-KWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKT 1346
Cdd:TIGR01612 1764 ELYNIIAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEiEKKSKSYLDDIEAKEFDRIINHFKKKLDHVNDKFTKEYSK 1843

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1347 VNDHTSKVRDLTSQVRHLEDE--LADTKGNlvQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALREN------- 1417
Cdd:TIGR01612 1844 INEGFDDISKSIENVKNSTDEnlLFDILNK--TKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQNNsgidlfd 1921

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1418 ----DILKSNNTNMETDLTRLKNRLKSAE----------DALKELKNSLSHAKTEKERLQNAFR-----EKTKQADHLNQ 1478
Cdd:TIGR01612 1922 niniAILSSLDSEKEDTLKFIPSPEKEPEiytkirdsydTLLDIFKKSQDLHKKEQDTLNIIFEnqqlyEKIQASNELKD 2001

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1479 LASQFDTKLTKLRNELQdtndKLITSDTERNALRNELQKLSQELKFGN-EQIQRKSDEYQTTIDDLAHSHRVS--EDSRL 1555
Cdd:TIGR01612 2002 TLSDLKYKKEKILNDVK----LLLHKFDELNKLSCDSQNYDTILELSKqDKIKEKIDNYEKEKEKFGIDFDVKamEEKFD 2077

                         1050      1060      1070
                   ....*....|....*....|....*....|....
gi 25151529   1556 NALQELEarKYEINDLTSRL---DSTEQRLATLQ 1586
Cdd:TIGR01612 2078 NDIKDIE--KFENNYKHSEKdnhDFSEEKDNIIQ 2109
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 512-1531 6.57e-11

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 68.28  E-value: 6.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    512 ELHKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRN---REKLN----EAQGALKKLHE---MAQDSEKNVDGTV 581
Cdd:pfam01576   75 EILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEeaaRQKLQlekvTTEAKIKKLEEdilLLEDQNSKLSKER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    582 SIKRTRsLSPGKTPLPPSEALRAVRNTFRNK-DNDIQQLERKLKIAESQVKEFlnkfenaDEARRRLDKQFADAKREISN 660
Cdd:pfam01576  155 KLLEER-ISEFTSNLAEEEEKAKSLSKLKNKhEAMISDLEERLKKEEKGRQEL-------EKAKRKLEGESTDLQEQIAE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    661 LQKSVDEAERNSRRTDDKLRA-------SEAERVAAEKARKFLEDELAKLQASF--QKSSTDDARKLRDEMDEHTNSIQE 731
Cdd:pfam01576  227 LQAQIAELRAQLAKKEEELQAalarleeETAQKNNALKKIRELEAQISELQEDLesERAARNKAEKQRRDLGEELEALKT 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    732 EFKTRID------ELNRRVENLLRENNR-LKSEVNPLKDKYRDLENEYNSTqrrIEEKETQIRYSDDIRRNIQKDLDDLR 804
Cdd:pfam01576  307 ELEDTLDttaaqqELRSKREQEVTELKKaLEEETRSHEAQLQEMRQKHTQA---LEELTEQLEQAKRNKANLEKAKQALE 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    805 EKYDRVHTDNEKILG---ELEHAQKAahlAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNN 881
Cdd:pfam01576  384 SENAELQAELRTLQQakqDSEHKRKK---LEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    882 DELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSrsgEIEKLNDLNQRLQKEKQDILNQKLKLDGD- 960
Cdd:pfam01576  461 KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE---EEEAKRNVERQLSTLQAQLSDMKKKLEEDa 537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    961 --VQALKETIRKLENELEKLRNENKElvgkearaRDAANQQLSRA-NLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKER 1037
Cdd:pfam01576  538 gtLEALEEGKKRLQRELEALTQQLEE--------KAAAYDKLEKTkNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQM 609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1038 LANigkggrisrdsttgtdggafgdrssvadpsrtrgaagstvfvpaAEDIESRGGGEIDipssgdvihgRDGRDGRDAG 1117
Cdd:pfam01576  610 LAE--------------------------------------------EKAISARYAEERD----------RAEAEAREKE 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1118 NRG---THTITNTKERIERIEK-NILDRYHDDELVEHKirevNDRWK--RELER----LENEKDDLERRIRELEDELSQI 1187
Cdd:pfam01576  636 TRAlslARALEEALEAKEELERtNKQLRAEMEDLVSSK----DDVGKnvHELERskraLEQQVEEMKTQLEELEDELQAT 711

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1188 GRGNDKTENDITELKRKHAAEI--------DKLKSDISALHDkHLSDLDDEKEQYGKAVENLKSVEDDLRDklnnLEKQL 1259
Cdd:pfam01576  712 EDAKLRLEVNMQALKAQFERDLqardeqgeEKRRQLVKQVRE-LEAELEDERKQRAQAVAAKKKLELDLKE----LEAQI 786

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1260 -ADSLNRENELEREKRdydekinsLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRS-EAKAL---ETTNTALKAQLQ 1334
Cdd:pfam01576  787 dAANKGREEAVKQLKK--------LQAQMKDLQRELEEARASRDEILAQSKESEKKLKNlEAELLqlqEDLAASERARRQ 858

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1335 AANDRiDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQ-------SDANKWR 1407
Cdd:pfam01576  859 AQQER-DELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTtelaaerSTSQKSE 937

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1408 GELDAALRENDILKSNNTNME-TDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTK-------QADHLNQL 1479
Cdd:pfam01576  938 SARQQLERQNKELKAKLQEMEgTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKklkevllQVEDERRH 1017

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   1480 ASQFDTKLTKLRNELQDTNDKLITSDTER---NALRNELQKLSQELKFGNEQIQR 1531
Cdd:pfam01576 1018 ADQYKDQAEKGNSRMKQLKRQLEEAEEEAsraNAARRKLQRELDDATESNESMNR 1072
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 716-1535 7.58e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 7.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    716 RKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRI---EEKETQirySDDI 792
Cdd:pfam02463  197 LQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIekeEEKLAQ---VLKE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    793 RRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRddyQKQKDEHARHLFDIRHKLETEIKGRQD 872
Cdd:pfam02463  274 NKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK---KKAEKELKKEKEEIEELEKELKELEIK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    873 LEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILN 952
Cdd:pfam02463  351 REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    953 QKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTdVNKQLEQDIR 1032
Cdd:pfam02463  431 ILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS-QKESKARSGL 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1033 DLKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADpsRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDgRD 1112
Cdd:pfam02463  510 KVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI--STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI-PK 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1113 GRDAGNRGTHTITNTKERIERIEKNILDRyhDDELVEHKIREVNDRWKRELERLENEKdDLERRIRELEDELSQIGRGND 1192
Cdd:pfam02463  587 LKLPLKSIAVLEIDPILNLAQLDKATLEA--DEDDKRAKVVEGILKDTELTKLKESAK-AKESGLRKGVSLEEGLAEKSE 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1193 KTENDITELKRKHAAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELERE 1272
Cdd:pfam02463  664 VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1273 KRD-----YDEKIN-SLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANdridhltkt 1346
Cdd:pfam02463  744 KIDeeeeeEEKSRLkKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA--------- 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1347 vndhtskvrdltsqvrhLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENdilksnntn 1426
Cdd:pfam02463  815 -----------------ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL--------- 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1427 metdltRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDT 1506
Cdd:pfam02463  869 ------LQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLL 942

                          810       820
                   ....*....|....*....|....*....
gi 25151529   1507 ERNALRNELQKLSQELKFGNEQIQRKSDE 1535
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLAKEE 971
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1124-1596 8.32e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 8.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1124 ITNTKERIERIEKNIldryHDDELVEHKIREVndrwKRELERLENEKDDLERRIRELEDELSQIGRGN---DKTENDITE 1200
Cdd:PRK03918  171 IKEIKRRIERLEKFI----KRTENIEELIKEK----EKELEEVLREINEISSELPELREELEKLEKEVkelEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1201 LKRKHAA---EIDKLKSDISALHD------KHLSDLDD------EKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNR 1265
Cdd:PRK03918  243 LEKELESlegSKRKLEEKIRELEErieelkKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1266 ENELEREKRDYDEK---INSLYGQNQKIKDEWDDFRNDADK--EIQKWKTDAYTVRSEAKALETTNtaLKAQLQAANDRI 1340
Cdd:PRK03918  323 INGIEERIKELEEKeerLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERLKKRLTGLTPEK--LEKELEELEKAK 400

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1341 DHLTKTVNDHTSKVRDLTSQVRHLED---ELADTKGN--LVQKEMDLEstqNRLRSLEDQHSTLqSDANKWRGELDAALR 1415
Cdd:PRK03918  401 EEIEEEISKITARIGELKKEIKELKKaieELKKAKGKcpVCGRELTEE---HRKELLEEYTAEL-KRIEKELKEIEEKER 476

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1416 EndiLKSNNTNMETDLTRLKN--RLKSAEDALKELKNSLShaKTEKERLQNAFREKTKQADHLNQLASQFDT------KL 1487
Cdd:PRK03918  477 K---LRKELRELEKVLKKESEliKLKELAEQLKELEEKLK--KYNLEELEKKAEEYEKLKEKLIKLKGEIKSlkkeleKL 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1488 TKLRNELQDTNDKLITSDTERNALRNELQKLSQE-LKFGNEQIQRKSDEYQTTID--DLAHSHRVSEDSRLNALQELEAR 1564
Cdd:PRK03918  552 EELKKKLAELEKKLDELEEELAELLKELEELGFEsVEELEERLKELEPFYNEYLElkDAEKELEREEKELKKLEEELDKA 631

                         490       500       510
                  ....*....|....*....|....*....|..
gi 25151529  1565 KYEINDLTSRLDSTEQRLATLQQDYIKADSER 1596
Cdd:PRK03918  632 FEELAETEKRLEELRKELEELEKKYSEEEYEE 663
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1806-2211 1.00e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 1.00e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1806 KTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEqwdssrfQLETK 1885
Cdd:TIGR04523   25 KNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLK-------KNKDK 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1886 MRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIdiqSKTSHE 1965
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK---EELENE 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1966 YQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQ---RVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKV 2042
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSlesQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2043 VNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRN-SSQLSDGWKKEKITLL----KKIELLENEKRRTD 2117
Cdd:TIGR04523  255 LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDlNNQKEQDWNKELKSELknqeKKLEEIQNQISQNN 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2118 AAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTN--KQREEQERQLIRMRQEKGQIEKVI 2195
Cdd:TIGR04523  335 KIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNleSQINDLESKIQNQEKLNQQKDEQI 414

                          410
                   ....*....|....*.
gi 25151529   2196 ENRERTHRNRIKQLED 2211
Cdd:TIGR04523  415 KKLQQEKELLEKEIER 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1128-1959 1.22e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 1.22e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1128 KERIERIekniLDRY-HDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELE---DELSQIGRGNDKTENDITELKR 1203
Cdd:pfam15921   73 KEHIERV----LEEYsHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQmerDAMADIRRRESQSQEDLRNQLQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1204 KHAAEIDKLKSdisaLHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELErekrdyDEKINSL 1283
Cdd:pfam15921  149 NTVHELEAAKC----LKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMS------TMHFRSL 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1284 YGQNQKIKDEwddfrndADKEIQKWKTDAYTVRSEAKALET-TNTALKAQLQAANDRIDHL-----------TKTVNDHT 1351
Cdd:pfam15921  219 GSAISKILRE-------LDTEISYLKGRIFPVEDQLEALKSeSQNKIELLLQQHQDRIEQLiseheveitglTEKASSAR 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1352 SKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRS--------LEDQHSTLQSDANKWRGELDAALRENDILKSN 1423
Cdd:pfam15921  292 SQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSelreakrmYEDKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1424 NTNMETDLTRLKNRLKSAEdalkelkNSLSHAKTEKERLQNAFREKTKQADHL-------NQLASQFDTKLTKLRNELQD 1496
Cdd:pfam15921  372 SGNLDDQLQKLLADLHKRE-------KELSLEKEQNKRLWDRDTGNSITIDHLrrelddrNMEVQRLEALLKAMKSECQG 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1497 TNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDsRLNALQE----LEARKYEINDLT 1572
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD-LTASLQEkeraIEATNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1573 SRLDSTEQRLATLQQDyikADSERDILS--DALRRFQSSANRVINFhtfvdggagYVDGVPGGTSVIggGPSAQRSGAYD 1650
Cdd:pfam15921  524 SRVDLKLQELQHLKNE---GDHLRNVQTecEALKLQMAEKDKVIEI---------LRQQIENMTQLV--GQHGRTAGAMQ 589

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1651 PSSGGVIGSGISGGPGGSDFgrEIEIGRGDSDQSDVAYPRSvpfppsaDFSSGRPGAASAGGRVINNldgtttvnmnggf 1730
Cdd:pfam15921  590 VEKAQLEKEINDRRLELQEF--KILKDKKDAKIRELEARVS-------DLELEKVKLVNAGSERLRA------------- 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1731 dIANLEGTLQSLLNKIEKLEMERNELRDtlarmkkkttethttinQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:pfam15921  648 -VKDIKQERDQLLNEVKTSRNELNSLSE-----------------DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE 709

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1811 SQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEqwdssrfQLETKMRESD 1890
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKN-------KLSQELSTVA 782

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   1891 SDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKlrrdlTKAESVENELRKTIDIQ 1959
Cdd:pfam15921  783 TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQR-----QEQESVRLKLQHTLDVK 846
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1128-1428 1.22e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1128 KERIERIEKNIldRYHDDELVEHKIREVndrwKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELK---RK 1204
Cdd:COG1196  219 KEELKELEAEL--LLLKLRELEAELEEL----EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQaeeYE 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1205 HAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLY 1284
Cdd:COG1196  293 LLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1285 GQNQKIKDEWDDFRNDADKEIQkwktdaytvrsEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHL 1364
Cdd:COG1196  372 AELAEAEEELEELAEELLEALR-----------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529 1365 EDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNME 1428
Cdd:COG1196  441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1319-1523 1.35e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.56  E-value: 1.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1319 AKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHST 1398
Cdd:COG4942   15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1399 LQSDANKWRGELDAALRE----------NDILKSNNTN--------METDLTRLKNRLKSAEDALKELKNSLSHAKTEKE 1460
Cdd:COG4942   95 LRAELEAQKEELAELLRAlyrlgrqpplALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 1461 RLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELK 1523
Cdd:COG4942  175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1736-2221 1.64e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.58  E-value: 1.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1736 EGTLQSLLNKIEKLEMERNELRDTLarmkkktTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEA 1815
Cdd:TIGR04523   67 EEKINNSNNKIKILEQQIKDLNDKL-------KKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKN 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1816 LKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKmresDSDTNK 1895
Cdd:TIGR04523  140 IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKK----IQKNKS 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1896 YQLQIASFESERQILTEKIKELdgalrlsdskvqdmkddTDKLRRDLTKAESVENELRKTIDIQSKTsheyqllKDQLLN 1975
Cdd:TIGR04523  216 LESQISELKKQNNQLKDNIEKK-----------------QQEINEKTTEISNTQTQLNQLKDEQNKI-------KKQLSE 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1976 TQNELNGANNRKQQLENELLNVRSEVRDYKQR------------VHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVV 2043
Cdd:TIGR04523  272 KQKELEQNNKKIKELEKQLNQLKSEISDLNNQkeqdwnkelkseLKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEL 351

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2044 NTMRTTETDLRQQL-------ETAKNEKRVATKELEDLKRRLAQLENERRNSSQLS-------DGWKKEKITLLKKIELL 2109
Cdd:TIGR04523  352 TNSESENSEKQRELeekqneiEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNqqkdeqiKKLQQEKELLEKEIERL 431

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2110 ENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNcaqlqQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKG 2189
Cdd:TIGR04523  432 KETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ-----LKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK 506

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 25151529   2190 QIE---KVIENRERTHRNRIKQLEDQIAILRDQLD 2221
Cdd:TIGR04523  507 ELEekvKDLTKKISSLKEKIEKLESEKKEKESKIS 541
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
495-976 1.89e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 66.63  E-value: 1.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   495 LEELRKIRGGGSS-EGDAELHKELMTKYEESIE--RNIE-----LESRGDDSQRKIAELEAELRRNREKLNEAQGALKKL 566
Cdd:PRK03918  275 IEELEEKVKELKElKEKAEEYIKLSEFYEEYLDelREIEkrlsrLEEEINGIEERIKELEEKEERLEELKKKLKELEKRL 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   567 HEMAQDSEKNVDGTVSIKRTRSLSPGKTPLPPSEalravrntfrnkdndiqqLERKLKIAESQVKEFLNKFENADEARRR 646
Cdd:PRK03918  355 EELEERHELYEEAKAKKEELERLKKRLTGLTPEK------------------LEKELEELEKAKEEIEEEISKITARIGE 416

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   647 LDKQFADAKREISNLQKS----------VDEAERNS--RRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDD 714
Cdd:PRK03918  417 LKKEIKELKKAIEELKKAkgkcpvcgreLTEEHRKEllEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   715 A-RKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLEnEYNSTQRRIEEKEtqirysDDIR 793
Cdd:PRK03918  497 KlKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKL------DELE 569

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   794 RNIQKDLDDLREKYDRVHTDNEKILGELE-------HAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRhKLETE 866
Cdd:PRK03918  570 EELAELLKELEELGFESVEELEERLKELEpfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE-ELRKE 648

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   867 IK--GRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKghqgkitHLENELHSRSGEIEKLNDLNQRLQ 944
Cdd:PRK03918  649 LEelEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE-------KLKEELEEREKAKKELEKLEKALE 721

                         490       500       510
                  ....*....|....*....|....*....|..
gi 25151529   945 kekqdilnqklkldgDVQALKETIRKLENELE 976
Cdd:PRK03918  722 ---------------RVEELREKVKKYKALLK 738
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 1162-1614 2.83e-10

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 65.48  E-value: 2.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1162 ELERLENEKDDLERRIRELEDELSQigrgndktendITELKRKHAAEIDKLKSDISALHD---------KHLSDLDDEKE 1232
Cdd:pfam05622    1 DLSEAQEEKDELAQRCHELDQQVSL-----------LQEEKNSLQQENKKLQERLDQLESgddsgtpggKKYLLLQKQLE 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1233 QYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELErekrdydekinSLYGQNQKIKDEWDDFRNDADKeIQKWKTda 1312
Cdd:pfam05622   70 QLQEENFRLETARDDYRIKCEELEKEVLELQHRNEELT-----------SLAEEAQALKDEMDILRESSDK-VKKLEA-- 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1313 yTVRSEAKALETTNTaLKAQLQAANDR-IDHLTKTVN--DHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRL 1389
Cdd:pfam05622  136 -TVETYKKKLEDLGD-LRRQVKLLEERnAEYMQRTLQleEELKKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEY 213

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1390 RSLEDQHSTLQSDANKWRGELDaALREndilksnnTNMETDLTRLKNRLKSAEDALKElKNSLSHAKTEKERLQNAFREK 1469
Cdd:pfam05622  214 KKLEEKLEALQKEKERLIIERD-TLRE--------TNEELRCAQLQQAELSQADALLS-PSSDPGDNLAAEIMPAEIREK 283

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1470 TKQADHLNQL-----ASQFDTKLTKLRNELQDTNDKLITSDTErnaLRNELQKLSqELKFGNEQIQRKSDEYQTTIDDLA 1544
Cdd:pfam05622  284 LIRLQHENKMlrlgqEGSYRERLTELQQLLEDANRRKNELETQ---NRLANQRIL-ELQQQVEELQKALQEQGSKAEDSS 359

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529   1545 HSHRVSE---DSRLNALQELEARKYEINDLTSRLDS-TEQRLATLQQDYIKADSERDILSDALRRFQSSANRVI 1614
Cdd:pfam05622  360 LLKQKLEehlEKLHEAQSELQKKKEQIEELEPKQDSnLAQKIDELQEALRKKDEDMKAMEERYKKYVEKAKSVI 433
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
602-1041 5.27e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 5.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   602 LRAVRNTFRNKDNDIQQLERK--------LKIAESQVKEFLNKFE-NADEARRRLDK-------------QFADAKREIS 659
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKdlherlngLESELAELDEEIERYEeQREQARETRDEadevleeheerreELETLEAEIE 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   660 NLQKSVDEAERnsRRTDDKLRASEAERVAAEkarkfLEDELAKLQAS--FQKSSTDDARKLRDEMDEHTNSIQ---EEFK 734
Cdd:PRK02224  262 DLRETIAETER--EREELAEEVRDLRERLEE-----LEEERDDLLAEagLDDADAEAVEARREELEDRDEELRdrlEECR 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   735 TRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIR--------------YSDDIRRNIQKDL 800
Cdd:PRK02224  335 VAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEeleeeieelrerfgDAPVDLGNAEDFL 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   801 DDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQR--------------DDYQKQKDEHARHLFDIR---HKL 863
Cdd:PRK02224  415 EELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEcgqpvegsphvetiEEDRERVEELEAELEDLEeevEEV 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   864 ETEI----------KGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKIThlenELHSRSGEI 933
Cdd:PRK02224  495 EERLeraedlveaeDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAA----EAEEEAEEA 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   934 -EKLNDLNQRLQ--KEKQDILNqklkldgDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKE- 1009
Cdd:PRK02224  571 rEEVAELNSKLAelKERIESLE-------RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEf 643

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 25151529  1010 ----LEDTKQDLKHSTDVNKQLEQDIRDLKERLANI 1041
Cdd:PRK02224  644 dearIEEAREDKERAEEYLEQVEEKLDELREERDDL 679
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1736-2141 5.81e-10

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 64.79  E-value: 5.81e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1736 EGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKET--RYRNIEDNLQDAEEERRALESRLQSAKTLLRSQE 1813
Cdd:COG4717   87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELE 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1814 EALKQRDEERRQMKSKMVAAELQargKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDT 1893
Cdd:COG4717  167 ELEAELAELQEELEELLEQLSLA---TEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1894 NKYQLQ--------IASFESERQILTEKIKELDGAL---------------RLSDSKVQDMKDDTDKLRRDLTKAESVEN 1950
Cdd:COG4717  244 RLKEARlllliaaaLLALLGLGGSLLSLILTIAGVLflvlgllallflllaREKASLGKEAEELQALPALEELEEEELEE 323

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1951 ELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLE--------NELLN---------VRSEVRDYKQRvHDVNN 2013
Cdd:COG4717  324 LLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQleeleqeiAALLAeagvedeeeLRAALEQAEEY-QELKE 402

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2014 RVSELQRQLQDANTEKNRVEDRFlsvekvvntmrtTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRnssQLSD 2093
Cdd:COG4717  403 ELEELEEQLEELLGELEELLEAL------------DEEELEEELEELEEELEELEEELEELREELAELEAELE---QLEE 467

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 25151529 2094 GWKKEKitLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMEREN 2141
Cdd:COG4717  468 DGELAE--LLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
PRK01156 PRK01156
chromosome segregation protein; Provisional
 530-1043 5.82e-10

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 64.92  E-value: 5.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   530 ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEK-NVDGTVSIKRTRSLSPGKTPLPPSE-------- 600
Cdd:PRK01156  208 DDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRyESEIKTAESDLSMELEKNNYYKELEerhmkiin 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   601 -ALRAVRNTFRNKDNDIQQLERKLKIAESqVKEFLNKFENADEARRRLDK---QFADAKREISNLQKSVDEAERNSRRTD 676
Cdd:PRK01156  288 dPVYKNRNYINDYFKYKNDIENKKQILSN-IDAEINKYHAIIKKLSVLQKdynDYIKKKSRYDDLNNQILELEGYEMDYN 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   677 DKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDdARKLRDEMDEHTNSIQEeFKTRIDELNRRVENLLRENNRLKS 756
Cdd:PRK01156  367 SYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEID-PDAIKKELNEINVKLQD-ISSKVSSLNQRIRALRENLDELSR 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   757 EVNPLK--------------DKYRDLENEYNSTQRRIEEK----ETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKIL 818
Cdd:PRK01156  445 NMEMLNgqsvcpvcgttlgeEKSNHIINHYNEKKSRLEEKireiEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKI 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   819 GELEHAQKAAhlaEQQLKEIKIQRDDYQKQKDEH-ARHLFDIRHKLETEIKGrqdlekNGARNNDELDKLRQTISDYESQ 897
Cdd:PRK01156  525 ESARADLEDI---KIKINELKDKHDKYEEIKNRYkSLKLEDLDSKRTSWLNA------LAVISLIDIETNRSRSNEIKKQ 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   898 INLLRRHNDELDTTIKghqgkithlenelhsrsgEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEK 977
Cdd:PRK01156  596 LNDLESRLQEIEIGFP------------------DDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKK 657

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   978 LRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:PRK01156  658 QIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINE 723
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
535-803 8.46e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 8.46e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  535 GDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDgtvSIKRTRSLSPGKTPLPPSEA----LRAVRNTFR 610
Cdd:COG4913  605 GFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE---ALQRLAEYSWDEIDVASAEReiaeLEAELERLD 681

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  611 NKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTD----DKLRASEAER 686
Cdd:COG4913  682 ASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELrallEERFAAALGD 761

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  687 VAAEKARKFLEDELAKLQAsfqksstdDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENL---LRENNRLKSEVNP-LK 762
Cdd:COG4913  762 AVERELRENLEERIDALRA--------RLNRAEEELERAMRAFNREWPAETADLDADLESLpeyLALLDRLEEDGLPeYE 833

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 25151529  763 DKYRDLENEynSTQRRIEEKETQIRYSddiRRNIQKDLDDL 803
Cdd:COG4913  834 ERFKELLNE--NSIEFVADLLSKLRRA---IREIKERIDPL 869
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1731-2220 8.85e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 8.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1731 DIANLEGTLQSLLNKIEKLEME-------RNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQ 1803
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQkqilrerLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1804 SAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEqwdssrfqlE 1883
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE---------E 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1884 TKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKtidiqskts 1963
Cdd:TIGR02168  433 AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG--------- 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1964 heYQLLKDQLLNTQNELNGANNRKQQL-------ENELLNVRSEVRDY---------KQRV-HDVNNRV---------SE 2017
Cdd:TIGR02168  504 --FSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALGGRLQAvvvenlnaaKKAIaFLKQNELgrvtflpldSI 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2018 LQRQLQDANTEKNRVEDRFLSV-----------EKVVNTMRTT---ETDLRQQLETAKNEK---RVATKELEDLKRRLAQ 2080
Cdd:TIGR02168  582 KGTEIQGNDREILKNIEGFLGVakdlvkfdpklRKALSYLLGGvlvVDDLDNALELAKKLRpgyRIVTLDGDLVRPGGVI 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2081 L-ENERRNSSQLSDgwKKEKITLLKKIELLENEKRRTDAAIRETALQREAIE-------KSLNAMERENKELYKNCAQLQ 2152
Cdd:TIGR02168  662 TgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEeeleqlrKELEELSRQISALRKDLARLE 739

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529   2153 QQIAQLEMENGNRILELTN--KQREEQERQLIRMRQEKGQIEKVIENRER---THRNRIKQLEDQIAILRDQL 2220
Cdd:TIGR02168  740 AEVEQLEERIAQLSKELTEleAEIEELEERLEEAEEELAEAEAEIEELEAqieQLKEELKALREALDELRAEL 812
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 614-828 9.07e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.24  E-value: 9.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  614 NDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKAR 693
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  694 KFLEDELAKLQASFQKSSTDDARKLR---------DEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDK 764
Cdd:COG4942  100 EAQKEELAELLRALYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529  765 YRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAA 828
Cdd:COG4942  180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1798-2220 1.27e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 63.91  E-value: 1.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1798 LESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRslrDKEEQWDS 1877
Cdd:TIGR00606  700 LQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE---EQETLLGT 776

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1878 SRFQLETKMRESDSDTNKYQLQIASFESERQIlTEKIKELDGA-LRLSDSKVQDMKDDTD-KLRRDLTKAEsvenELRKT 1955
Cdd:TIGR00606  777 IMPEEESAKVCLTDVTIMERFQMELKDVERKI-AQQAAKLQGSdLDRTVQQVNQEKQEKQhELDTVVSKIE----LNRKL 851

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1956 IDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKnrvedr 2035
Cdd:TIGR00606  852 IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK------ 925

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2036 flsvEKVVNTMRTtetdlrqqletaknEKRVATKELEDLKRRLAQLENERRN-SSQLSDGWKKEKITllkkielLENEKR 2114
Cdd:TIGR00606  926 ----EELISSKET--------------SNKKAQDKVNDIKEKVKNIHGYMKDiENKIQDGKDDYLKQ-------KETELN 980

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2115 RTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQ--ERQLIRMRQEKGQIE 2192
Cdd:TIGR00606  981 TVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEmgQMQVLQMKQEHQKLE 1060

                          410       420       430
                   ....*....|....*....|....*....|.
gi 25151529   2193 KVIENRERTHR---NRIKQLEDQIAILRDQL 2220
Cdd:TIGR00606 1061 ENIDLIKRNHVlalGRQKGYEKEIKHFKKEL 1091
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 511-1588 1.81e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 63.53  E-value: 1.81e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    511 AELHKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSLS 590
Cdd:TIGR01612  747 GEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIK 826

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    591 PGKTPLPPSEaLRAVRNTFRNKDNDIQQLE----RKLKIAESQVKEFLNKFEN--ADEARRRLDKQFADAKREISNLQKS 664
Cdd:TIGR01612  827 EDEIFKIINE-MKFMKDDFLNKVDKFINFEnnckEKIDSEHEQFAELTNKIKAeiSDDKLNDYEKKFNDSKSLINEINKS 905

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    665 VDEAERNS---RRTDDKLRASEAERVAAEKarkfledelaklqasFQKSSTDDARKLRDEMD--EHTNSIQEEFKTRIDe 739
Cdd:TIGR01612  906 IEEEYQNIntlKKVDEYIKICENTKESIEK---------------FHNKQNILKEILNKNIDtiKESNLIEKSYKDKFD- 969

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    740 lnrrvenllrenNRLKSEVNPLKDKYRDLE-NEYNSTQRRIeeketqIRYSDDIRRNIQKDLDD-LREKYDrvhtDNEKI 817
Cdd:TIGR01612  970 ------------NTLIDKINELDKAFKDASlNDYEAKNNEL------IKYFNDLKANLGKNKENmLYHQFD----EKEKA 1027

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    818 LGELEhaqkaahlaeqqlkeikiqrddyqkQKDEHA-RHLFDIRHKLETEIKG-RQDLEKNGARNNDELDKlrqtisdye 895
Cdd:TIGR01612 1028 TNDIE-------------------------QKIEDAnKNIPNIEIAIHTSIYNiIDEIEKEIGKNIELLNK--------- 1073

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 sqiNLLRRHNDELdTTIKGHQGKITHLENELHSRSGEIEKLNDLNqrlqKEKQDILNQKLKLDGDVQALKETIRKLENEL 975
Cdd:TIGR01612 1074 ---EILEEAEINI-TNFNEIKEKLKHYNFDDFGKEENIKYADEIN----KIKDDIKNLDQKIDHHIKALEEIKKKSENYI 1145

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    976 EKLRNENKELvgkearaRDAANQQLSRANLlnKELEDTKQDLKHSTDVNKQLEQDIRDLKERLAnigkggRISRDSTTgt 1055
Cdd:TIGR01612 1146 DEIKAQINDL-------EDVADKAISNDDP--EEIEKKIENIVTKIDKKKNIYDEIKKLLNEIA------EIEKDKTS-- 1208

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1056 dggafgdRSSVADPSRTRGAAGSTVFVPAAEdiESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGTHTItntkERIERIE 1135
Cdd:TIGR01612 1209 -------LEEVKGINLSYGKNLGKLFLEKID--EEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGI----EMDIKAE 1275

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1136 KNILDRYHDDELVEHKIREVNDrwkrelerlENEKDDLERRIRELED--ELSQIGRGNDKTENDITElKRKHAAEIDKLK 1213
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHD---------ENISDIREKSLKIIEDfsEESDINDIKKELQKNLLD-AQKHNSDINLYL 1345

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1214 SDISALHD----KHLSDLDDEKEQYGKAVE-NLKSVEDDLrDKLNNLEKQLADSLNreneLEREKrdydekinslygqnQ 1288
Cdd:TIGR01612 1346 NEIANIYNilklNKIKKIIDEVKEYTKEIEeNNKNIKDEL-DKSEKLIKKIKDDIN----LEECK--------------S 1406

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1289 KIKDEWDDfrNDADKEIQKWKTDAYTVRSEakalETTNTALKAQLQAANDRIDHLTKTVndhtskvrdltsqvrhledEL 1368
Cdd:TIGR01612 1407 KIESTLDD--KDIDECIKKIKELKNHILSE----ESNIDTYFKNADENNENVLLLFKNI-------------------EM 1461

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1369 ADTKGNLVQKEM------DLESTQNRLRSLEDQHSTLQSDANKWRgeldAALRENDILKSnntNMETDLTRLKNRLKSAe 1442
Cdd:TIGR01612 1462 ADNKSQHILKIKkdnatnDHDFNINELKEHIDKSKGCKDEADKNA----KAIEKNKELFE---QYKKDVTELLNKYSAL- 1533

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1443 dalkELKNSLSHAKTEKERLQNAFREKTKQadhLNQLASQFDTKLTKLRNE---LQD-------TNDKLITSDTERNALR 1512
Cdd:TIGR01612 1534 ----AIKNKFAKTKKDSEIIIKEIKDAHKK---FILEAEKSEQKIKEIKKEkfrIEDdaakndkSNKAAIDIQLSLENFE 1606

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1513 NELQKLSQELKFGN------EQIQRKSDEYQTTIDDLAHSHRVSEDSRLNA-LQELEARKYEINDLTSRLDSTEQRLATL 1585
Cdd:TIGR01612 1607 NKFLKISDIKKKINdclketESIEKKISSFSIDSQDTELKENGDNLNSLQEfLESLKDQKKNIEDKKKELDELDSEIEKI 1686


                   ...
gi 25151529   1586 QQD 1588
Cdd:TIGR01612 1687 EID 1689
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
592-1016 1.95e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.86  E-value: 1.95e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  592 GKTPLPPSEALRAVRNTFR---NKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDK--QFADAKREISNLQKSVD 666
Cdd:COG4717   63 GRKPELNLKELKELEEELKeaeEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELA 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  667 EAERNSrrtdDKLRASEAERVAAEKARKFLEDELAKLQAsfqksstdDARKLRDEMDEHTNSIQEEFKTRIDELNRRVEN 746
Cdd:COG4717  143 ELPERL----EELEERLEELRELEEELEELEAELAELQE--------ELEELLEQLSLATEEELQDLAEELEELQQRLAE 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  747 LLRENNRLKSEVNPLKDKYRDLENEYNSTQ--RRIEEKETQIR----------YSDDIRRNIQKDLD----------DLR 804
Cdd:COG4717  211 LEEELEEAQEELEELEEELEQLENELEAAAleERLKEARLLLLiaaallallgLGGSLLSLILTIAGvlflvlgllaLLF 290

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  805 EKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDI-------------------RHKLET 865
Cdd:COG4717  291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRieelqellreaeeleeelqLEELEQ 370

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  866 EIKgrQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKG-----HQGKITHLENELHSRSGEIEKLNDLN 940
Cdd:COG4717  371 EIA--ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEleellEALDEEELEEELEELEEELEELEEEL 448

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529  941 QRLQKEKQDILNQKLKLDGDvqalkETIRKLENELEKLRNENKELVgKEARARDAANQQLSRAnllNKELEDTKQD 1016
Cdd:COG4717  449 EELREELAELEAELEQLEED-----GELAELLQELEELKAELRELA-EEWAALKLALELLEEA---REEYREERLP 515
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
780-1584 2.02e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.40  E-value: 2.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  780 EEKETQirysDDIRRnIQKDLDDLREKYDRVHTDNEKI--LGEL-EHAQKAAHlAEQQLKEIKIQRDDYQKQKDEHARHL 856
Cdd:COG4913  219 EEPDTF----EAADA-LVEHFDDLERAHEALEDAREQIelLEPIrELAERYAA-ARERLAELEYLRAALRLWFAQRRLEL 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  857 fdirhkLETEIkgrqdlekngARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQG-KITHLENELhsrsgeiek 935
Cdd:COG4913  293 ------LEAEL----------EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGdRLEQLEREI--------- 347

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  936 lndlnQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANllnKELEDTKQ 1015
Cdd:COG4913  348 -----ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAE---AALRDLRR 419

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1016 DLKhstdvnkQLEQDIRDLKERLANIGKGGRISRDsttgtdggafgdrssvadpsRTRGAAGSTvfvpaaediesrgggE 1095
Cdd:COG4913  420 ELR-------ELEAEIASLERRKSNIPARLLALRD--------------------ALAEALGLD---------------E 457

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1096 IDIPSSGDVIHGRDG-RDGRDAGNRGTHTITNT---KERIERIEKNILDRYHDDE-LVEHKIREVNdrwkRELERLENEK 1170
Cdd:COG4913  458 AELPFVGELIEVRPEeERWRGAIERVLGGFALTllvPPEHYAAALRWVNRLHLRGrLVYERVRTGL----PDPERPRLDP 533

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1171 DDLERRI--------RELEDELSQigRGNDKTENDITELKR-KHAAEIDKLKSDISALHDKhlsdlDDEKEQYGKAV--- 1238
Cdd:COG4913  534 DSLAGKLdfkphpfrAWLEAELGR--RFDYVCVDSPEELRRhPRAITRAGQVKGNGTRHEK-----DDRRRIRSRYVlgf 606

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1239 ENlksveddlRDKLNNLEKQLAdslnrenELEREKRDYDEKINSL---YGQNQKIKDEWDDFRNDADKEIqkwktDAYTV 1315
Cdd:COG4913  607 DN--------RAKLAALEAELA-------ELEEELAEAEERLEALeaeLDALQERREALQRLAEYSWDEI-----DVASA 666

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1316 RSEAKALEttntALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLED- 1394
Cdd:COG4913  667 EREIAELE----AELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDl 742

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1395 QHSTLQSDANKWRGELDAALRENDILKsnntNMETDLTRLKNRLKSAEDALkelknslshaktekERLQNAFREKTK--Q 1472
Cdd:COG4913  743 ARLELRALLEERFAAALGDAVERELRE----NLEERIDALRARLNRAEEEL--------------ERAMRAFNREWPaeT 804

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1473 ADHLNQLAS--QFDTKLTKLRNE------------LQDTNDKLITS-----DTERNALRNELQKLSQELK---FGNE--- 1527
Cdd:COG4913  805 ADLDADLESlpEYLALLDRLEEDglpeyeerfkelLNENSIEFVADllsklRRAIREIKERIDPLNDSLKripFGPGryl 884

                        810       820       830       840       850       860
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1528 QI---QRKSDEYQTTIDDLahsHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLAT 1584
Cdd:COG4913  885 RLearPRPDPEVREFRQEL---RAVTSGASLFDEELSEARFAALKRLIERLRSEEEESDR 941
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1743-2219 2.59e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 2.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1743 LNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSaktllrsqeeaLKQRDEE 1822
Cdd:TIGR04523  144 LTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN-----------LKKKIQK 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1823 RRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQwdsSRFQLETKMRESDSDTNKyqlqIAS 1902
Cdd:TIGR04523  213 NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK---IKKQLSEKQKELEQNNKK----IKE 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1903 FESERQILTEKIKELDgalrlsDSKVQD-MKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELN 1981
Cdd:TIGR04523  286 LEKQLNQLKSEISDLN------NQKEQDwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1982 GANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQ-----------------------------------DAN 2026
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQnqeklnqqkdeqikklqqekellekeierlketiiKNN 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2027 TEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQ-------LENERRNSSQLSDGWKKEK 2099
Cdd:TIGR04523  440 SEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSkekelkkLNEEKKELEEKVKDLTKKI 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2100 ITLLKKIELLENEKRRTDAAIREtalqreaIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQER 2179
Cdd:TIGR04523  520 SSLKEKIEKLESEKKEKESKISD-------LEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 25151529   2180 QLirmRQEKGQIEKVIENRERThrnrIKQLEDQIAILRDQ 2219
Cdd:TIGR04523  593 QK---EKEKKDLIKEIEEKEKK----ISSLEKELEKAKKE 625
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1151-1609 2.72e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.48  E-value: 2.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1151 KIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRkhaaEIDKLKSDISALHD-KHLSDLDD 1229
Cdd:COG4717   64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELRE----ELEKLEKLLQLLPLyQELEALEA 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1230 EKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWK 1309
Cdd:COG4717  140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1310 TDAYTVRSEAKALETtntalKAQLQAANDRIDHLTKTVNDhTSKVRDLTSQVRHLEDELADTKG--------------NL 1375
Cdd:COG4717  220 EELEELEEELEQLEN-----ELEAAALEERLKEARLLLLI-AAALLALLGLGGSLLSLILTIAGvlflvlgllallflLL 293

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1376 VQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAalrENDILKSNNTNMETDLTRLKNRLKSAEDALKELKnsLSHA 1455
Cdd:COG4717  294 AREKASLGKEAEELQALPALEELEEEELEELLAALGL---PPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEEL 368

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1456 KTEKERLQN--------AFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERnaLRNELQKLSQELKFGNE 1527
Cdd:COG4717  369 EQEIAALLAeagvedeeELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEELEE 446

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1528 QIQRKSDEYQTT---IDDLAHSHRVSEdsrlnALQELEARKyeindltsrldsteQRLATLQQDYIKADSERDILSDALR 1604
Cdd:COG4717  447 ELEELREELAELeaeLEQLEEDGELAE-----LLQELEELK--------------AELRELAEEWAALKLALELLEEARE 507


                 ....*
gi 25151529 1605 RFQSS 1609
Cdd:COG4717  508 EYREE 512
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1776-2140 3.17e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.48  E-value: 3.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1776 QKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKskmvaaelqargKEAQLRHLNEQLKNLR 1855
Cdd:COG4717   85 EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA------------LEAELAELPERLEELE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1856 TDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTnkyQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDT 1935
Cdd:COG4717  153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1936 DKLRRDLTKAEsVENELRK-------------------------------------------TIDIQSKTSHEYQLLKDQ 1972
Cdd:COG4717  230 EQLENELEAAA-LEERLKEarlllliaaallallglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEELQ 308

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1973 LLNTQNELNGA--NNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVE-DRFLSVEKVvntmrTT 2049
Cdd:COG4717  309 ALPALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEiAALLAEAGV-----ED 383

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2050 ETDLRQQLEtAKNEKRVATKELEDLKRRLAQLENERRNSSQLSD--GWKKEKITLLKKIELLENEKRRTDAAIRETALQR 2127
Cdd:COG4717  384 EEELRAALE-QAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAEL 462

                        410
                 ....*....|...
gi 25151529 2128 EAIEKSLNAMERE 2140
Cdd:COG4717  463 EQLEEDGELAELL 475
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 674-1559 3.36e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.50  E-value: 3.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    674 RTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDD---ARKLRDEMDEHTNSiqEEFKTRIDELNRRVENLLRE 750
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKnalQEQLQAETELCAEA--EEMRARLAARKQELEEILHE 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    751 nnrLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTD-------NEKILGELEH 823
Cdd:pfam01576   80 ---LESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDillledqNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    824 AQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLR- 902
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRa 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    903 ---RHNDELdttikghQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKL---KLDGDVQALKETIRKLENELE 976
Cdd:pfam01576  237 qlaKKEEEL-------QAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAarnKAEKQRRDLGEELEALKTELE 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    977 ----------KLRNENKELVG-------KEARARDAANQQLSRA-----NLLNKELEDTKQDlKHSTDVNKQ-LEQDIRD 1033
Cdd:pfam01576  310 dtldttaaqqELRSKREQEVTelkkaleEETRSHEAQLQEMRQKhtqalEELTEQLEQAKRN-KANLEKAKQaLESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1034 LKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVfvpaaedieSRGGGEID-IPSSGDVIHGRDGRD 1112
Cdd:pfam01576  389 LQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKL---------SKLQSELEsVSSLLNEAEGKNIKL 459

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1113 GRDAGNRGTHtITNTKERIERIEKNILDryhddelVEHKIREVNDRWKRELERLENE---KDDLERRIRELEDELSQIGR 1189
Cdd:pfam01576  460 SKDVSSLESQ-LQDTQELLQEETRQKLN-------LSTRLRQLEDERNSLQEQLEEEeeaKRNVERQLSTLQAQLSDMKK 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1190 gndKTEND------ITELKRKHAAEIDKLKSDI---SALHDKhlsdLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQ-- 1258
Cdd:pfam01576  532 ---KLEEDagtleaLEEGKKRLQRELEALTQQLeekAAAYDK----LEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqk 604

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1259 -----LADSLN----------------RENE-----LEREKRDYDEKINSLYGQNQKIKDEWDDF---RNDADKEIQKWK 1309
Cdd:pfam01576  605 kfdqmLAEEKAisaryaeerdraeaeaREKEtralsLARALEEALEAKEELERTNKQLRAEMEDLvssKDDVGKNVHELE 684

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1310 TDAYTVRSEAKALETTNTALKAQLQAANDRidHLTKTVNDHTSKV-----------------RDLTSQVRHLEDELADTK 1372
Cdd:pfam01576  685 RSKRALEQQVEEMKTQLEELEDELQATEDA--KLRLEVNMQALKAqferdlqardeqgeekrRQLVKQVRELEAELEDER 762

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1373 GNLVQK-------EMDL--------------ESTQNRLRSLEDQHSTLQ---SDANKWRGELDAALRENDilkSNNTNME 1428
Cdd:pfam01576  763 KQRAQAvaakkklELDLkeleaqidaankgrEEAVKQLKKLQAQMKDLQrelEEARASRDEILAQSKESE---KKLKNLE 839

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1429 TDLTRLKNRLKSAEDALKelknslsHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQD-------TNDKL 1501
Cdd:pfam01576  840 AELLQLQEDLAASERARR-------QAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEeqsntelLNDRL 912

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529   1502 ITSDTERNALRNELQ---KLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNALQ 1559
Cdd:pfam01576  913 RKSTLQVEQLTTELAaerSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALE 973
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 614-1041 3.92e-09

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 61.79  E-value: 3.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    614 NDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVdeaernsrrtddklrasEAERVAAEKAR 693
Cdd:pfam06160   86 KALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTL-----------------LANRFSYGPAI 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    694 KFLEDELAKLQASFQKSST-------DDARKLRDEMDEHTNSIQEEFKtRIDELNRRVENLlrennrLKSEVNPLKDKYR 766
Cdd:pfam06160  149 DELEKQLAEIEEEFSQFEEltesgdyLEAREVLEKLEEETDALEELME-DIPPLYEELKTE------LPDQLEELKEGYR 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    767 DLENE-YNSTQRRIEEKETQIRysDDIRRNIQK----DLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQ 841
Cdd:pfam06160  222 EMEEEgYALEHLNVDKEIQQLE--EQLEENLALlenlELDEAEEALEEIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDY 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    842 RDDYQKQKDEharhlfdirhkLETEIkgrQDLEKNGARNNDELDKLRQtisdYESQINLLRRHNDELDTTIKGHQGKITH 921
Cdd:pfam06160  300 LEHAEEQNKE-----------LKEEL---ERVQQSYTLNENELERVRG----LEKQLEELEKRYDEIVERLEEKEVAYSE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    922 LENELhsrsgeIEKLNDLNQrLQKEKQDILNQKLKLDGDVQALKETIRKLENELE--KLRNENKELVGKEARARDAANQQ 999
Cdd:pfam06160  362 LQEEL------EEILEQLEE-IEEEQEEFKESLQSLRKDELEAREKLDEFKLELReiKRLVEKSNLPGLPESYLDYFFDV 434

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 25151529   1000 LSRANLLNKELEDTKQDLKhstDVNKQLE---QDIRDLKERLANI 1041
Cdd:pfam06160  435 SDEIEDLADELNEVPLNMD---EVNRLLDeaqDDVDTLYEKTEEL 476
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 522-1041 3.98e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.44  E-value: 3.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    522 EESIERNIELESRG-DDSQRKIAELEAELRRNREKLNEAQGALK-KLHEMAQDSeknvDGTVSIKRTRSLSPG------K 593
Cdd:pfam15921   73 KEHIERVLEEYSHQvKDLQRRLNESNELHEKQKFYLRQSVIDLQtKLQEMQMER----DAMADIRRRESQSQEdlrnqlQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    594 TPLPPSEALRAVR-NTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEAR-RRLDKQFADAKREISNLQKSVDEAern 671
Cdd:pfam15921  149 NTVHELEAAKCLKeDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAISKI--- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    672 srrtddkLRASEAErVAAEKARKF-LEDELAKLQASFQ-------KSSTDDARKLRDEMD--------------EHTNSI 729
Cdd:pfam15921  226 -------LRELDTE-ISYLKGRIFpVEDQLEALKSESQnkielllQQHQDRIEQLISEHEveitgltekassarSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    730 QEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYnstQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDR 809
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMY---EDKIEELEKQLVLANSELTEARTERDQFSQESGN 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    810 VHTDNEKILGELEHAQKAAHLAEQQLKEIkIQRDDYQKQKDEHARHLFDIRH-----------KLETEIKGRQDLEKNGA 878
Cdd:pfam15921  375 LDDQLQKLLADLHKREKELSLEKEQNKRL-WDRDTGNSITIDHLRRELDDRNmevqrleallkAMKSECQGQMERQMAAI 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    879 R-NNDELDKLRQTISDYESQINLLRRHNDELDT---TIKGHQGKITHLENELHSRSGEIEKLN----DLNQRLQKEKQDI 950
Cdd:pfam15921  454 QgKNESLEKVSSLTAQLESTKEMLRKVVEELTAkkmTLESSERTVSDLTASLQEKERAIEATNaeitKLRSRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    951 lnQKLKLDGD--------VQALKETIRKLENELEKLRN--EN-KELVGKEARArdAANQQLSRANLlNKELEDTKQDLKH 1019
Cdd:pfam15921  534 --QHLKNEGDhlrnvqteCEALKLQMAEKDKVIEILRQqiENmTQLVGQHGRT--AGAMQVEKAQL-EKEINDRRLELQE 608

                          570       580
                   ....*....|....*....|..
gi 25151529   1020 STDVNKQLEQDIRDLKERLANI 1041
Cdd:pfam15921  609 FKILKDKKDAKIRELEARVSDL 630
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 614-1037 5.00e-09

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 61.39  E-value: 5.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   614 NDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVdeaernsrrtddklrasEAERVAAEKAR 693
Cdd:PRK04778  105 HEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSL-----------------LANRFSFGPAL 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   694 KFLEDELAKLQASFQKSST-------DDARKLRDEMDEHTNsiqeEFKTRIDElnrrVENLLRE-NNRLKSEVNPLKDKY 765
Cdd:PRK04778  168 DELEKQLENLEEEFSQFVEltesgdyVEAREILDQLEEELA----ALEQIMEE----IPELLKElQTELPDQLQELKAGY 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   766 RDLENE-YNstqrrIEEKetqirysddirrNIQKDLDDLREKYDRvhtdNEKILGELEHAQkaahlAEQQLKEIKIQRDd 844
Cdd:PRK04778  240 RELVEEgYH-----LDHL------------DIEKEIQDLKEQIDE----NLALLEELDLDE-----AEEKNEEIQERID- 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   845 yqkqkdeharHLFDIrhkLETEIKGRQDLEKNgarnndeldklrqtISDYESQINLLRRHNDELDTtikghqgKITHL-- 922
Cdd:PRK04778  293 ----------QLYDI---LEREVKARKYVEKN--------------SDTLPDFLEHAKEQNKELKE-------EIDRVkq 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   923 -----ENELHSRSGEIEKLNDLNQRLQKEKQDILNQKL---KLDGDVQALKETIRKLENELEKLRNENKELVGKEARARD 994
Cdd:PRK04778  339 sytlnESELESVRQLEKQLESLEKQYDEITERIAEQEIaysELQEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEARE 418

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   995 AANQ----------QLSRANL--------------------LNKELEDTKQDLKhstDVNKQLEQ---DIRDLKER 1037
Cdd:PRK04778  419 KLERyrnklheikrYLEKSNLpglpedylemffevsdeieaLAEELEEKPINME---AVNRLLEEateDVETLEEE 491
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1971-2242 6.37e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.55  E-value: 6.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRflsvekvVNTMRTTE 2050
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-------LAELEKEI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2051 TDLRQQLETAKnekrvatkelEDLKRRLAQLENERRNSsqlsdgwkkekitllkKIELLENEKRRTDAAIRETALQR--E 2128
Cdd:COG4942   93 AELRAELEAQK----------EELAELLRALYRLGRQP----------------PLALLLSPEDFLDAVRRLQYLKYlaP 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2129 AIEKSLNAMERENKELykncaqlqqQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQ 2208
Cdd:COG4942  147 ARREQAEELRADLAEL---------AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217

                        250       260       270
                 ....*....|....*....|....*....|....
gi 25151529 2209 LEDQIAILRDQLDGERRRRREYVDRSMVNDIGRL 2242
Cdd:COG4942  218 LQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1124-1585 6.46e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 6.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1124 ITNTKERIERIEKNIL--DRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRgndkTENDITEL 1201
Cdd:PRK03918  140 ILESDESREKVVRQILglDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLR----EINEISSE 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1202 KRKHAAEIDKLKSDISALhDKHLSDLDDEKEQYGKAVENLKSVEDDLRdklnNLEKQLADSLNRENELEREKRDYDE--K 1279
Cdd:PRK03918  216 LPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLEEKIR----ELEERIEELKKEIEELEEKVKELKElkE 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1280 INSLYGQNQKIKDEWDDFRNDADKEIQKWktdaytvRSEAKALEttntalkAQLQAANDRidhltktvndhTSKVRDLTS 1359
Cdd:PRK03918  291 KAEEYIKLSEFYEEYLDELREIEKRLSRL-------EEEINGIE-------ERIKELEEK-----------EERLEELKK 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1360 QVRHLEDELADTKGNlVQKEMDLESTQNRLRSLEDQHSTLQSDanKWRGELDAALRENDILKSNNTNMETDLTRLKNRLK 1439
Cdd:PRK03918  346 KLKELEKRLEELEER-HELYEEAKAKKEELERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIK 422

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1440 SAEDALKELKNS-----LSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTnDKLITSDTERNALR-- 1512
Cdd:PRK03918  423 ELKKAIEELKKAkgkcpVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKel 501

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529  1513 -NELQKLSQELK-FGNEQIQRKSDEYQTTIDDLA--HSHRVSEDSRLNALQELEARKYEINdltSRLDSTEQRLATL 1585
Cdd:PRK03918  502 aEQLKELEEKLKkYNLEELEKKAEEYEKLKEKLIklKGEIKSLKKELEKLEELKKKLAELE---KKLDELEEELAEL 575
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
600-1241 7.22e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 7.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  600 EALRAVRNTFRnkdnDIQQLERKLKIAESQVK---EFLNKFENADEARRRLDK-QFADAKREISNLQKSVDEAERNSRRT 675
Cdd:COG4913  225 EAADALVEHFD----DLERAHEALEDAREQIEllePIRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEEL 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  676 DDKLRASEAERVAAEKARKFLEDELAKLQASFQKSSTDD-----------------ARKLRDEMDEHTNSI--------- 729
Cdd:COG4913  301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRleqlereierlereleeRERRRARLEALLAALglplpasae 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  730 -----QEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRR---IEEKETQIRysDDIRRNIQKDLD 801
Cdd:COG4913  381 efaalRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRksnIPARLLALR--DALAEALGLDEA 458

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  802 DL---------REKYDRVHTDNEKILG--------ELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIR---H 861
Cdd:COG4913  459 ELpfvgelievRPEEERWRGAIERVLGgfaltllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDslaG 538

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  862 KLET-----------EIKGRQDLEKngARNNDELDKLRQTISDyESQI-NLLRRHndELDTTIKGHQG---------KIT 920
Cdd:COG4913  539 KLDFkphpfrawleaELGRRFDYVC--VDSPEELRRHPRAITR-AGQVkGNGTRH--EKDDRRRIRSRyvlgfdnraKLA 613

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  921 HLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDG---------DVQALKETIRKLENELEKLRNENKELvgkear 991
Cdd:COG4913  614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELERLDASSDDL------ 687

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  992 arDAANQQLSRanlLNKELEDTKQDLkhstdvnKQLEQDIRDLKERLANIgkggrisrdsttgtdggafgdRSSVADPSR 1071
Cdd:COG4913  688 --AALEEQLEE---LEAELEELEEEL-------DELKGEIGRLEKELEQA---------------------EEELDELQD 734

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1072 TRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVihGRDGRDGRDAGNRgthTITNTKERIERIEKNILDRYHD------- 1144
Cdd:COG4913  735 RLEAAEDLARLELRALLEERFAAALGDAVEREL--RENLEERIDALRA---RLNRAEEELERAMRAFNREWPAetadlda 809

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1145 ------------DELVEHKIREVNDRWKRELER------------LENEKDDLERRIRELEDELSQIGRGNDKTendIT- 1199
Cdd:COG4913  810 dleslpeylallDRLEEDGLPEYEERFKELLNEnsiefvadllskLRRAIREIKERIDPLNDSLKRIPFGPGRY---LRl 886

                        730       740       750       760
                 ....*....|....*....|....*....|....*....|..
gi 25151529 1200 ELKRKHAAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENL 1241
Cdd:COG4913  887 EARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
515-1042 8.62e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.21  E-value: 8.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   515 KELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEmaqdseknvdgtvsiKRTRSLSPGKT 594
Cdd:PRK02224  240 DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE---------------ERDDLLAEAGL 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   595 PLPPSEALRAVRNTFrnkDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRR 674
Cdd:PRK02224  305 DDADAEAVEARREEL---EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVED 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   675 TDDKLRASEAERVAAEKARKFLEDELaklqasfqksstDDARKLRDEMDEHTNSIQEEFKTRIDELnRRVENLLRENNRL 754
Cdd:PRK02224  382 RREEIEELEEEIEELRERFGDAPVDL------------GNAEDFLEELREERDELREREAELEATL-RTARERVEEAEAL 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   755 KSEVN------PLKDkyrdleneyNSTQRRIEEKETQIrysddirRNIQKDLDDLREKYDRVhtdnEKILGELEHAQKaa 828
Cdd:PRK02224  449 LEAGKcpecgqPVEG---------SPHVETIEEDRERV-------EELEAELEDLEEEVEEV----EERLERAEDLVE-- 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   829 hlAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDEL 908
Cdd:PRK02224  507 --AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL 584

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   909 DTTIKGhQGKITHLENELHSRSGEIEKLNDLNQRLQkEKQDILNQKLKldgdvqALKETIRKLENELEKLRNEnkelvgk 988
Cdd:PRK02224  585 KERIES-LERIRTLLAAIADAEDEIERLREKREALA-ELNDERRERLA------EKRERKRELEAEFDEARIE------- 649

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   989 EARA-RDAANQQLSRANLLNKELEDTKQDLKHSTD-VNKQLEQdIRDLKERLANIG 1042
Cdd:PRK02224  650 EAREdKERAEEYLEQVEEKLDELREERDDLQAEIGaVENELEE-LEELRERREALE 704
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
933-1524 9.79e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 9.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   933 IEKLNDLNQRLQKEKQDILNQKLKLDGDVQA---LKETIRKLENELEKLRNENKELVGKEARARdaanQQLSRANLLNKE 1009
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRtenIEELIKEKEKELEEVLREINEISSELPELR----EELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1010 LEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTtgtdggafgdrssvadpsrtrgaagstvfvpaaEDIE 1089
Cdd:PRK03918  233 LEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI---------------------------------EELE 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1090 SRGG--GEIDIPSSGDVIHGRDGRDGRDAGNRGTHTITNTKERIERIEKNILDRYHDDELVEhKIREVNDRWKRELERLE 1167
Cdd:PRK03918  280 EKVKelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELE 358

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1168 nEKDDLERRIRELEDELSQI-----GRGNDKTENDITELKRKHaaeiDKLKSDISALHDKhLSDLDDEKEQYGKAVENLK 1242
Cdd:PRK03918  359 -ERHELYEEAKAKKEELERLkkrltGLTPEKLEKELEELEKAK----EEIEEEISKITAR-IGELKKEIKELKKAIEELK 432

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1243 SVE-------------------DDLRDKLNNLEKQLADSLNRENELEREKRDYDEKIN---------SLYGQNQKIKDEW 1294
Cdd:PRK03918  433 KAKgkcpvcgrelteehrkellEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkeseliklkELAEQLKELEEKL 512

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1295 DDFrnDADKEIQKWKtdaytvrsEAKALETTNTALKAQLQAANDRIdhltKTVNDHTSKVRDLTSQVRHLEDELADTKGN 1374
Cdd:PRK03918  513 KKY--NLEELEKKAE--------EYEKLKEKLIKLKGEIKSLKKEL----EKLEELKKKLAELEKKLDELEEELAELLKE 578

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1375 LVQKEM-DLESTQNRLRSLEDQHSTLQSdANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLS 1453
Cdd:PRK03918  579 LEELGFeSVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529  1454 haKTEKERLQNAFREKTKQadhLNQLASQFDTkLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKF 1524
Cdd:PRK03918  658 --EEEYEELREEYLELSRE---LAGLRAELEE-LEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER 722
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
859-1042 1.14e-08

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 60.64  E-value: 1.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  859 IRHKLETEI-KGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELdttikghqgkithlENELHSRSGEIEKLN 937
Cdd:COG2433  382 LEELIEKELpEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEEL--------------EAELEEKDERIERLE 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  938 DlnqRLQKEKQDIlNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELED-TKQD 1016
Cdd:COG2433  448 R---ELSEARSEE-RREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVEKfTKEA 523

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 25151529 1017 LKHSTDVNKQLEQDI----------RDLKERLANIG 1042
Cdd:COG2433  524 IRRLEEEYGLKEGDVvylrdasgagRSTAELLAEAG 559
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 649-1457 1.19e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 60.84  E-value: 1.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    649 KQFADAKREISNLQKSVDEAERNSR-------RTDDKLRA---SEAERVAAEKARKfLEDELAKLQASFQKSSTDDARKL 718
Cdd:TIGR01612  620 KKAIDLKKIIENNNAYIDELAKISPyqvpehlKNKDKIYStikSELSKIYEDDIDA-LYNELSSIVKENAIDNTEDKAKL 698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    719 RD---EMDEHTNSIQEeFKTRIDELNrrVENLLRENNRLKSEVNPLKDK-YRDLENEYNSTQRRIEEKETQI-------- 786
Cdd:TIGR01612  699 DDlksKIDKEYDKIQN-METATVELH--LSNIENKKNELLDIIVEIKKHiHGEINKDLNKILEDFKNKEKELsnkindya 775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    787 RYSDDIRRNIQKdLDDLREKY-DRVHTDNEKIlgelEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLET 865
Cdd:TIGR01612  776 KEKDELNKYKSK-ISEIKNHYnDQINIDNIKD----EDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDK 850

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    866 EIkgrqDLEKNGARNNDeldklrqtiSDYESQINLLRRHNDELDTTikghqgKITHLENELHSRSGEIeklNDLNQRLQK 945
Cdd:TIGR01612  851 FI----NFENNCKEKID---------SEHEQFAELTNKIKAEISDD------KLNDYEKKFNDSKSLI---NEINKSIEE 908

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    946 EKQDIlNQKLKLDGDV---QALKETIRKLENELEKLR---NENKELVgKEARARDAANQQLSRANLLNK--ELEDTKQDL 1017
Cdd:TIGR01612  909 EYQNI-NTLKKVDEYIkicENTKESIEKFHNKQNILKeilNKNIDTI-KESNLIEKSYKDKFDNTLIDKinELDKAFKDA 986

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1018 KHST--DVNKQLEQDIRDLKERLANiGKGGRISRDsttgtdggaFGDRSSvadpsrtrgaagstvfvpAAEDIESRG-GG 1094
Cdd:TIGR01612  987 SLNDyeAKNNELIKYFNDLKANLGK-NKENMLYHQ---------FDEKEK------------------ATNDIEQKIeDA 1038

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1095 EIDIPSSGDVIHGrdgrdgrdagnrgthTITNTKERIER-IEKNIlDRYHDDELVEHKIREVNDRWKRELERLENEKDDL 1173
Cdd:TIGR01612 1039 NKNIPNIEIAIHT---------------SIYNIIDEIEKeIGKNI-ELLNKEILEEAEINITNFNEIKEKLKHYNFDDFG 1102

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1174 ER-------RIRELEDELSQIGRGNDKTENDITELKRKHAAEIDKLKSDISALH---DKHLSdlDDEKEQYGKAVENLKS 1243
Cdd:TIGR01612 1103 KEenikyadEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEdvaDKAIS--NDDPEEIEKKIENIVT 1180

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1244 VeddlRDKLNNLEKQLADSLNRENELEREKRDYDE--KINSLYGQN------QKIKDEWDDFRNDAdKEIQKWKTDAYTV 1315
Cdd:TIGR01612 1181 K----IDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkGINLSYGKNlgklflEKIDEEKKKSEHMI-KAMEAYIEDLDEI 1255

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1316 RSEAKALETTntalkaqlQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKgnlvQKEMDLESTQNRLRSLEDQ 1395
Cdd:TIGR01612 1256 KEKSPEIENE--------MGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIR----EKSLKIIEDFSEESDINDI 1323

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   1396 HSTLQ---SDANKWRGELDAALRE----NDILKSNntNMETDLTRLKNRLKSAEDALKELKNSLSHAKT 1457
Cdd:TIGR01612 1324 KKELQknlLDAQKHNSDINLYLNEianiYNILKLN--KIKKIIDEVKEYTKEIEENNKNIKDELDKSEK 1390
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1746-2217 1.53e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 1.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1746 IEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRlqsaKTLLRSQEEALKQRDEERRQ 1825
Cdd:PRK03918  181 LEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL----KEEIEELEKELESLEGSKRK 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1826 MKSKMVAAELQARGKEAQLRHLNEQLKnlrtdldnahtDIRSLRDKEEQWDssrfQLETKMRESDSDTNKYQLQIASFES 1905
Cdd:PRK03918  257 LEEKIRELEERIEELKKEIEELEEKVK-----------ELKELKEKAEEYI----KLSEFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1906 ERQILTEKIKELDGalrlSDSKVQDMKDDTDKLRRDL----TKAESVENELRKTIDIQSKTSHEYQLLKDQLlntQNELN 1981
Cdd:PRK03918  322 EINGIEERIKELEE----KEERLEELKKKLKELEKRLeeleERHELYEEAKAKKEELERLKKRLTGLTPEKL---EKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1982 GANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQ---------RQLQDANTEKNRVEDRFLSVEKVVNTMRTTETD 2052
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEK 474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2053 LRQ------QLETA-KNEKRVAT-----KELEDLKRRLAQLENER--------RNSSQLSDGWKKEKITL---LKKIELL 2109
Cdd:PRK03918  475 ERKlrkelrELEKVlKKESELIKlkelaEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLkkeLEKLEEL 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2110 ENEKRRTDAAIREtalqreaIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQReEQERQLIRMRQEKG 2189
Cdd:PRK03918  555 KKKLAELEKKLDE-------LEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK-ELEREEKELKKLEE 626

                         490       500
                  ....*....|....*....|....*...
gi 25151529  2190 QIEKVIENRERThRNRIKQLEDQIAILR 2217
Cdd:PRK03918  627 ELDKAFEELAET-EKRLEELRKELEELE 653
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1733-2213 1.55e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1733 ANLEGTLQSLLNKIEklEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLlrsq 1812
Cdd:PRK02224  183 SDQRGSLDQLKAQIE--EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETL---- 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1813 EEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESdsd 1892
Cdd:PRK02224  257 EAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEEC--- 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1893 tnkyQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSK----TSHEYQL 1968
Cdd:PRK02224  334 ----RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdAPVDLGN 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1969 LKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQ---------------------RVHDVNNRVSELQRQLQDANT 2027
Cdd:PRK02224  410 AEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2028 EKNRVEDRFLSVEKVVNTMRTTETdLRQQLETAknEKRVATKElEDLKRRLAQLENERRNSSQLSDgwkkekitllkkie 2107
Cdd:PRK02224  490 EVEEVEERLERAEDLVEAEDRIER-LEERREDL--EELIAERR-ETIEEKRERAEELRERAAELEA-------------- 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2108 llENEKRRTDAAIRETALQREAIE-KSLNAMERENKElykncaqlqqqiaqlEMENGNRILELTNKqREEQERQLIRMRQ 2186
Cdd:PRK02224  552 --EAEEKREAAAEAEEEAEEAREEvAELNSKLAELKE---------------RIESLERIRTLLAA-IADAEDEIERLRE 613

                         490       500       510
                  ....*....|....*....|....*....|
gi 25151529  2187 EKGQI-EKVIENRER--THRNRIKQLEDQI 2213
Cdd:PRK02224  614 KREALaELNDERRERlaEKRERKRELEAEF 643
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 515-1335 1.89e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    515 KELMTKYEESIERNIELESRGDDSQR--KIAELEAELRRNREKLNEAQGALKKLHEMA--QDSEKNVDGTVSIKRTRSLS 590
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKlkEQAKKALEYYQLKEKLELEEEYLLYLDYLKlnEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    591 PGKTPLPPSEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAER 670
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    671 NSRRTDDKLRASEAERVAAEKARKFLEDELakLQASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRE 750
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQ--EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    751 NNRLKSEVNPLKDKYRDLENEynsTQRRIEEKETQIRysddIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQkaahL 830
Cdd:pfam02463  414 ARQLEDLLKEEKKEELEILEE---EEESIELKQGKLT----EEKEELEKQELKLLKDELELKKSEDLLKETQLVK----L 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    831 AEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDT 910
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    911 TIKGhQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQaLKETIRKLENELEKLRNENKELVGKE- 989
Cdd:pfam02463  563 RQKL-VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATL-EADEDDKRAKVVEGILKDTELTKLKEs 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    990 ARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKggRISRDSTTGTDGGAFGDRSSVADP 1069
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI--LRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1070 SRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRdagnrgthtitntKERIERIEKNILDRYHDDELVE 1149
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE-------------EEKSELSLKEKELAEEREKTEK 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1150 HKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENdiTELKRKHAAEIDKLKSDISALHDKHLSDLDD 1229
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE--EELEELALELKEEQKLEKLAEEELERLEEEI 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1230 EKEQYgKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWK 1309
Cdd:pfam02463  864 TKEEL-LQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLL 942

                          810       820
                   ....*....|....*....|....*.
gi 25151529   1310 TDAYTVRSEAKALETTNTALKAQLQA 1335
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLA 968
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 846-1043 1.89e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  846 QKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENE 925
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  926 LHSRSGEIEKLNDLNQRL--QKEKQDILNQK--LKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLS 1001
Cdd:COG4942   99 LEAQKEELAELLRALYRLgrQPPLALLLSPEdfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 25151529 1002 RANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGK 1043
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ 220
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 824-1588 2.40e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 59.68  E-value: 2.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    824 AQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTIsdyesqinlLRR 903
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---------FQG 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    904 HNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRnenk 983
Cdd:TIGR00606  299 TDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLA---- 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    984 elvgkearardaanqqlsranlLNKELEdtkqDLKHSTDVNKQLEQDIRDLKERLAniGKGGRISRDSTTGTDGGAFGDR 1063
Cdd:TIGR00606  375 ----------------------TRLELD----GFERGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQE 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1064 ssvadpsrtrgaagstvfvpAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGtHTITNTKERIERIEKNILDRYH 1143
Cdd:TIGR00606  427 --------------------QADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL-QQLEGSSDRILELDQELRKAER 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1144 DDELVEHKirEVNDRWKRELERLENEKDDLERRIRELEDELSQIGRgnDKTENDITELKRKHAAEIDKLKSDISALHDKH 1223
Cdd:TIGR00606  486 ELSKAEKN--SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNH--HTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1224 LSDLDDE---KEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLygqNQKIKD--EWDDFR 1298
Cdd:TIGR00606  562 LTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY---EDKLFDvcGSQDEE 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1299 NDAD---KEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDEladtkgnl 1375
Cdd:TIGR00606  639 SDLErlkEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDK-------- 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1376 vqkemdLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHA 1455
Cdd:TIGR00606  711 ------LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1456 K------TEKERLQNAFREKTKQADHL--NQLASQFDTKLTKLRNELQDTNDKL--ITSDTErnalrnELQKLSQELKFG 1525
Cdd:TIGR00606  785 KvcltdvTIMERFQMELKDVERKIAQQaaKLQGSDLDRTVQQVNQEKQEKQHELdtVVSKIE------LNRKLIQDQQEQ 858

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   1526 NEQIQRKSDEYQT---TIDDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQD 1588
Cdd:TIGR00606  859 IQHLKSKTNELKSeklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQE 924
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1731-1928 2.58e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1811 SQEEALKQR-----------------------DEERRQMKSKMVAAELQARGKEaqLRHLNEQLKNLRTDLDNAHTDIRS 1867
Cdd:COG4942  101 AQKEELAELlralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEE--LRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1868 LRDKEEQ----WDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKV 1928
Cdd:COG4942  179 LLAELEEeraaLEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1732-2193 2.74e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.35  E-value: 2.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1732 IANLEGTLQSLLNKIEK----LEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKT 1807
Cdd:pfam05483  224 IQHLEEEYKKEINDKEKqvslLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKM 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1808 LLRSQEEALKQRdEERRQMKSKMVAAELQArgKEAQLRHLNE----------QLKNLRTDLDN-AHTDIRSLRDKEEQWD 1876
Cdd:pfam05483  304 SLQRSMSTQKAL-EEDLQIATKTICQLTEE--KEAQMEELNKakaahsfvvtEFEATTCSLEElLRTEQQRLEKNEDQLK 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1877 SSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDgalrlSDSKVQDMKDDTDKLRRDLTKAESVENELRKTI 1956
Cdd:pfam05483  381 IITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD-----EKKQFEKIAEELKGKEQELIFLLQAREKEIHDL 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1957 DIQ---SKTSHEYQLLKDQLLNTQNElngannrKQQLENELLNVRSE--VRDYKQRVHDVNNRVSELQRQLQDANTEKNR 2031
Cdd:pfam05483  456 EIQltaIKTSEEHYLKEVEDLKTELE-------KEKLKNIELTAHCDklLLENKELTQEASDMTLELKKHQEDIINCKKQ 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2032 vEDRFLsveKVVNTMRTTETDLRQQLETAKNEKRvatKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLEN 2111
Cdd:pfam05483  529 -EERML---KQIENLEEKEMNLRDELESVREEFI---QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2112 EKRRTDAAIRETALQREAIEKSLNAmerENKELykNCAQLQQQIAQLEMENG-NRILELTNKQREEQERQLIRMRQEKGQ 2190
Cdd:pfam05483  602 QIENKNKNIEELHQENKALKKKGSA---ENKQL--NAYEIKVNKLELELASAkQKFEEIIDNYQKEIEDKKISEEKLLEE 676


                   ...
gi 25151529   2191 IEK 2193
Cdd:pfam05483  677 VEK 679
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 616-1249 3.15e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 59.47  E-value: 3.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    616 IQQLERKLKIAESQVKEFLNKFenaDEARRRLDKQFADAKREIsnlQKSVDEAERNSRRTDDKLRASEAERVAAE-KARK 694
Cdd:pfam12128  260 LSHLHFGYKSDETLIASRQEER---QETSAELNQLLRTLDDQW---KEKRDELNGELSAADAAVAKDRSELEALEdQHGA 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    695 FLEDELAKLQA------SFQ----------KSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEV 758
Cdd:pfam12128  334 FLDADIETAAAdqeqlpSWQselenleerlKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    759 --------NPLKDKYRDLENEYNSTQRRI-----------------EEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTD 813
Cdd:pfam12128  414 eddlqaleSELREQLEAGKLEFNEEEYRLksrlgelklrlnqatatPELLLQLENFDERIERAREEQEAANAEVERLQSE 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    814 NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHK------------LETEIKGRQDL--EKNGAR 879
Cdd:pfam12128  494 LRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKeapdweqsigkvISPELLHRTDLdpEVWDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    880 NNDE-------LDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKlndlnqrLQKEKQDILN 952
Cdd:pfam12128  574 VGGElnlygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK-------ASREETFART 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    953 QKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKElEDTKQDLKHSTDVNKQLEQDIR 1032
Cdd:pfam12128  647 ALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLE-EQKEQKREARTEKQAYWQVVEG 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1033 DLKERLANIgkggrisrdsttgtdggafgdRSSVADPSRTRGAAGSTVFVPAAEDIESRGggeIDipssGDVIHGRDgrd 1112
Cdd:pfam12128  726 ALDAQLALL---------------------KAAIAARRSGAKAELKALETWYKRDLASLG---VD----PDVIAKLK--- 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1113 grdagnRGTHTITNTKERIERIEKNILdRYHDdelvehkirEVNDRWKRELERLENEKDDLERRIRELEDELSQI----- 1187
Cdd:pfam12128  775 ------REIRTLERKIERIAVRRQEVL-RYFD---------WYQETWLQRRPRLATQLSNIERAISELQQQLARLiadtk 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1188 --------GRG-NDKTENDITELKRKHAAEIDKL----------KSDISALH-----DKHLSDLDDEKEQYGKAVENLKS 1243
Cdd:pfam12128  839 lrraklemERKaSEKQQVRLSENLRGLRCEMSKLatlkedanseQAQGSIGErlaqlEDLKLKRDYLSESVKKYVEHFKN 918


                   ....*.
gi 25151529   1244 VEDDLR 1249
Cdd:pfam12128  919 VIADHS 924
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
638-1049 3.33e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.01  E-value: 3.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  638 ENADEARRRLDKQFADAKREISNLQKSVDEAE---RNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQksstdd 714
Cdd:COG4717   53 KEADELFKPQGRKPELNLKELKELEEELKEAEekeEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ------ 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  715 ARKLRDEMDEHTNSIqEEFKTRIDELNRRVEnllrennrlksEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDdirr 794
Cdd:COG4717  127 LLPLYQELEALEAEL-AELPERLEELEERLE-----------ELRELEEELEELEAELAELQEELEELLEQLSLAT---- 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  795 niQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEI--KIQRDDYQKQKDEHARHLFDI------------- 859
Cdd:COG4717  191 --EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLenELEAAALEERLKEARLLLLIAaallallglggsl 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  860 -------------------------RHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKG 914
Cdd:COG4717  269 lsliltiagvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE 348

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  915 HQGKITHLENELHSRsgEIEKLNDLNQRLQKEKQ----DILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVgkEA 990
Cdd:COG4717  349 LQELLREAEELEEEL--QLEELEQEIAALLAEAGvedeEELRAALEQAEEYQELKEELEELEEQLEELLGELEELL--EA 424

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529  991 RARDAANQQLSRanlLNKELEDTKQDLkhstdvnKQLEQDIRDLKERLANIGKGGRISR 1049
Cdd:COG4717  425 LDEEELEEELEE---LEEELEELEEEL-------EELREELAELEAELEQLEEDGELAE 473
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 512-1012 4.02e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.60  E-value: 4.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    512 ELHKELMTKYEESIERNIELESRGDDSQRKIA-------ELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIK 584
Cdd:pfam05557   13 QLQNEKKQMELEHKRARIELEKKASALKRQLDresdrnqELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    585 RTRSLSpgktplppseaLRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKS 664
Cdd:pfam05557   93 NEKESQ-----------LADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQ 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    665 VDEAE-----------RNSRRTDDKLRA----SEAERVA---AEKAR---------------KFLEDELAKLQASFQKSS 711
Cdd:pfam05557  162 QSSLAeaeqrikelefEIQSQEQDSEIVknskSELARIPeleKELERlrehnkhlnenienkLLLKEEVEDLKRKLEREE 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    712 TDDAR---------KLRDEMDEHTNSIQ---------EEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYN 773
Cdd:pfam05557  242 KYREEaatlelekeKLEQELQSWVKLAQdtglnlrspEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELA 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    774 STQRRIEEKETQIRYSDDIRRNIQKDL-------DDLR---EKYDRVHTDNEKILGELEHAQKAAHLAEQ---QLKEIKI 840
Cdd:pfam05557  322 QYLKKIEDLNKKLKRHKALVRRLQRRVllltkerDGYRailESYDKELTMSNYSPQLLERIEEAEDMTQKmqaHNEEMEA 401

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    841 QRDdyqkQKDEHARHLFDIRHKLETEIKG--RQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGH--Q 916
Cdd:pfam05557  402 QLS----VAEEELGGYKQQAQTLERELQAlrQQESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEMELERRclQ 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    917 GKITHLENE-LHSRSGEIeklndlnqrlQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDA 995
Cdd:pfam05557  478 GDYDPKKTKvLHLSMNPA----------AEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFKEVLD 547

                          570
                   ....*....|....*..
gi 25151529    996 ANQQLSRANLLNKELED 1012
Cdd:pfam05557  548 LRKELESAELKNQRLKE 564
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 522-797 4.35e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.93  E-value: 4.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    522 EESIERNIeLESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRtrslspgktplppsea 601
Cdd:TIGR02169  781 LNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI---------------- 843

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    602 lravrntfrnkDNDIQQLERKLKIAESQVK--EFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERnsrrtddKL 679
Cdd:TIGR02169  844 -----------DLKEQIKSIEKEIENLNGKkeELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER-------KI 905

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    680 RASEAERvaaEKARKFLEDELAKLQASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSE-- 757
Cdd:TIGR02169  906 EELEAQI---EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEye 982

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529    758 -----VNPLKDKYRDLENEYNSTQRRIEEKETQIRYS-----DDIRRNIQ 797
Cdd:TIGR02169  983 evlkrLDELKEKRAKLEEERKAILERIEEYEKKKREVfmeafEAINENFN 1032
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 600-1442 4.91e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.90  E-value: 4.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    600 EALRAVRNTFRNKDNDIQ---QLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTD 676
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQmelKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLD 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    677 DKLRASEAERVAAEKARKFLEDELAKLqasFQKSstddarklrdemDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKS 756
Cdd:TIGR00606  269 NEIKALKSRKKQMEKDNSELELKMEKV---FQGT------------DEQLNDLYHNHQRTVREKERELVDCQRELEKLNK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    757 EVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQ--KDLDDL-REKYDRVHTDNE---KILGELEHAQKAAHL 830
Cdd:TIGR00606  334 ERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAtrLELDGFeRGPFSERQIKNFhtlVIERQEDEAKTAAQL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    831 -AEQQLKEIKIQR--DDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGAR---NNDELDKLRQTISDYESQINLLrrh 904
Cdd:TIGR00606  414 cADLQSKERLKQEqaDEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQlegSSDRILELDQELRKAERELSKA--- 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    905 ndELDTTIKGHQGKITHLENE----LHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIR----------- 969
Cdd:TIGR00606  491 --EKNSLTETLKKEVKSLQNEkadlDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRhsdeltsllgy 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    970 -----KLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELED-TKQDLKHSTDV-----NKQLEQDIRDLKERL 1038
Cdd:TIGR00606  569 fpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESkEEQLSSYEDKLfdvcgSQDEESDLERLKEEI 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1039 ANIGKGGRISRDSTTGTDG--GAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEID-IPSSGDVIHGRDGRDGRD 1115
Cdd:TIGR00606  649 EKSSKQRAMLAGATAVYSQfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDkLKSTESELKKKEKRRDEM 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1116 AG---------NRGTHTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRE---------LERLENEKDDLERRI 1177
Cdd:TIGR00606  729 LGlapgrqsiiDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdvtiMERFQMELKDVERKI 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1178 RELEDELSqiGRGNDKTENDITELKRKHAAEIDKLKSDISALH-------------DKHLSDLDDEKEQYGKAVENLKSV 1244
Cdd:TIGR00606  809 AQQAAKLQ--GSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRkliqdqqeqiqhlKSKTNELKSEKLQIGTNLQRRQQF 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1245 EDDLRDK---LNNLEKQLADSLNRENELEREKRDY----DEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRS 1317
Cdd:TIGR00606  887 EEQLVELsteVQSLIREIKDAKEQDSPLETFLEKDqqekEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD 966

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1318 ----EAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLE 1393
Cdd:TIGR00606  967 gkddYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ 1046

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 25151529   1394 DQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAE 1442
Cdd:TIGR00606 1047 MQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
495-974 5.05e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  495 LEELRKIRGGGSSEGDAELhKELMTKYEESIERNIELEsrgdDSQRKIAELEAELRRNREKLNEAQGALKKLhEMAQDSE 574
Cdd:COG4717   55 ADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYA----ELQEELEELEEELEELEAELEELREELEKL-EKLLQLL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  575 KNVDGTVSIKRTRSLSPGKTplppsEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEAR-RRLDKQFAD 653
Cdd:COG4717  129 PLYQELEALEAELAELPERL-----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  654 AKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSstddARKLRDEMDEHTNSIQEEF 733
Cdd:COG4717  204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLA----LLGLGGSLLSLILTIAGVL 279

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  734 KTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTD 813
Cdd:COG4717  280 FLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  814 NEKILGELEHAQKAAHLAEQQLKEIK--IQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGarnndELDKLRQTI 891
Cdd:COG4717  360 EEELQLEELEQEIAALLAEAGVEDEEelRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL-----DEEELEEEL 434

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  892 SDYESQINLLRRHNDELDTTIKGHQGKITHLENelhsrSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKL 971
Cdd:COG4717  435 EELEEELEELEEELEELREELAELEAELEQLEE-----DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEY 509


                 ...
gi 25151529  972 ENE 974
Cdd:COG4717  510 REE 512
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 797-1587 6.41e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 6.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  797 QKDLDDLREKYDRVhtdnEKILGELEhaqkaahlaeQQLKEIKIQRDD---YQKQKDE----HARHLFDIRHKLETEIkg 869
Cdd:COG1196  178 ERKLEATEENLERL----EDILGELE----------RQLEPLERQAEKaerYRELKEElkelEAELLLLKLRELEAEL-- 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  870 rQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQD 949
Cdd:COG1196  242 -EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  950 ILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQ 1029
Cdd:COG1196  321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1030 DIRDLKERLANIgkggrisrdsttgtdggafgdrssvadpsrtrgaagstvfvpaaediesrgggeidipssgdvihgrd 1109
Cdd:COG1196  401 QLEELEEAEEAL-------------------------------------------------------------------- 412

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1110 grdgrdagnrgthtitntKERIERIEKNILDRyhddelvehkirevndrwKRELERLENEKDDLERRIRELEDELSQIGR 1189
Cdd:COG1196  413 ------------------LERLERLEEELEEL------------------EEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1190 GNDKTENDITELKRKHA---AEIDKLKSDISALHDKHLSDLDDEKEQYGKAvenlksvEDDLRDKLNNLEKQLADSLNRE 1266
Cdd:COG1196  457 EEEALLELLAELLEEAAlleAALAELLEELAEAAARLLLLLEAEADYEGFL-------EGVKAALLLAGLRGLAGAVAVL 529

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1267 NELEREKRDYDEKINSLYGQNQKIKDEWDdfrndADKEIQKWKTDaytvRSEAKALETTNTALKAQLQAANDRIDHLTKT 1346
Cdd:COG1196  530 IGVEAAYEAALEAALAAALQNIVVEDDEV-----AAAAIEYLKAA----KAGRATFLPLDKIRARAALAAALARGAIGAA 600

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1347 VNDHTSKVRDLTSQVRHLEDELADTkgNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGEL--DAALRENDILKSNN 1424
Cdd:COG1196  601 VDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLtgGSRRELLAALLEAE 678

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1425 TNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITS 1504
Cdd:COG1196  679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1505 DTERNALRNELQKLSQELK-FG--NeqiqrksdeyqttiddlahshrvsedsrLNALQELEARKYEINDLTSRLDSTEQR 1581
Cdd:COG1196  759 PPDLEELERELERLEREIEaLGpvN----------------------------LLAIEEYEELEERYDFLSEQREDLEEA 810


                 ....*.
gi 25151529 1582 LATLQQ 1587
Cdd:COG1196  811 RETLEE 816
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1328-1474 9.38e-08

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 55.32  E-value: 9.38e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1328 ALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSdaNKwr 1407
Cdd:COG1579   14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN--NK-- 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529 1408 gELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQAD 1474
Cdd:COG1579   90 -EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 614-1028 1.01e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.42  E-value: 1.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    614 NDIQQLERKLKIAESQVKEFLNK--------------FENADEARRRLDKQFADAKREISNL--QKSVDEAERNSRRTDD 677
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKkdhltkeledikmsLQRSMSTQKALEEDLQIATKTICQLteEKEAQMEELNKAKAAH 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    678 KLRASE--------AERVAAEKAR-KFLEDELAKLQASFQKSSTDdarklRDEMDEHTNSIQ---EEFKTRIDElnrrVE 745
Cdd:pfam05483  348 SFVVTEfeattcslEELLRTEQQRlEKNEDQLKIITMELQKKSSE-----LEEMTKFKNNKEvelEELKKILAE----DE 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    746 NLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGE----L 821
Cdd:pfam05483  419 KLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHcdklL 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    822 EHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLL 901
Cdd:pfam05483  499 LENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSI 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    902 RRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKeKQDILNQKLkldgdvQALKETIRKLENELEKLRNE 981
Cdd:pfam05483  579 EYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK-KGSAENKQL------NAYEIKVNKLELELASAKQK 651

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 25151529    982 NKELVgkEARARDAANQQLSRANLLnKELEDTKQDLKHSTDVNKQLE 1028
Cdd:pfam05483  652 FEEII--DNYQKEIEDKKISEEKLL-EEVEKAKAIADEAVKLQKEID 695
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 732-1505 1.06e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 57.75  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    732 EFKTRIDELNRRVENLLRENNRLKSevnpLKDKYRDLENEYNSTQRRIEEkeTQIRYSDDIRRNIQKDldDLREKYDRVH 811
Cdd:TIGR01612  386 EFLEEIKKIAKQRAIFFYNAKKLKH----LEILYKHQEDILNNFHKTIER--LIFEKPDPNNNNIFKD--DFDEFNKPIP 457

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    812 TDNEKILgelehAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNgarnnDELDKLRQTI 891
Cdd:TIGR01612  458 KSKLKAL-----EKRFFEIFEEEWGSYDIKKDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKP-----DEVPSKNIIG 527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    892 SDYESQINLLRRhnDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKL 971
Cdd:TIGR01612  528 FDIDQNIKAKLY--KEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLEL 605

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    972 ENELEKLRNENKEL-----VGKEARARDAANQQLSRANLLNKELEDTKQDLKHST---DVNKQLEQDIRDLKERLANIGK 1043
Cdd:TIGR01612  606 KEKIKNISDKNEYIkkaidLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTiksELSKIYEDDIDALYNELSSIVK 685

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1044 GGRIsrDSTTgtDGGAFGDRSSVADPSRTRGAAGSTVFVPA-AEDIESRGGGEID-IPSSGDVIHGrdgrdgrDAGNRGT 1121
Cdd:TIGR01612  686 ENAI--DNTE--DKAKLDDLKSKIDKEYDKIQNMETATVELhLSNIENKKNELLDiIVEIKKHIHG-------EINKDLN 754

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1122 HTITNTKERIERIEKNILD-RYHDDEL--VEHKIREVNDRWKRELErLENEKDDLERRIRELEDELSQ-IGRGNDKTEND 1197
Cdd:TIGR01612  755 KILEDFKNKEKELSNKINDyAKEKDELnkYKSKISEIKNHYNDQIN-IDNIKDEDAKQNYDKSKEYIKtISIKEDEIFKI 833

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1198 ITELKRKHAAEIDKLKSDISaLHDKHLSDLDDEKEQYGKAVENLKSVEDDlrDKLNNLEKQLADSLNRENELEREKRDYD 1277
Cdd:TIGR01612  834 INEMKFMKDDFLNKVDKFIN-FENNCKEKIDSEHEQFAELTNKIKAEISD--DKLNDYEKKFNDSKSLINEINKSIEEEY 910

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1278 EKINSLYGQNQKIK------DEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTK--TVND 1349
Cdd:TIGR01612  911 QNINTLKKVDEYIKicentkESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKdaSLND 990

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1350 HTSKVRDLTSQVRHLEDELADTKGNLVQKEMD--LESTQNRLRSLEDQ-----------HSTLQSDANKWRGEL--DAAL 1414
Cdd:TIGR01612  991 YEAKNNELIKYFNDLKANLGKNKENMLYHQFDekEKATNDIEQKIEDAnknipnieiaiHTSIYNIIDEIEKEIgkNIEL 1070

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1415 RENDILKSNNTNMeTDLTRLKNRLK-------------SAEDALKELKNSLSHAKTEKERLQNAFRE-KTKQADHLNQLA 1480
Cdd:TIGR01612 1071 LNKEILEEAEINI-TNFNEIKEKLKhynfddfgkeeniKYADEINKIKDDIKNLDQKIDHHIKALEEiKKKSENYIDEIK 1149

                          810       820
                   ....*....|....*....|....*
gi 25151529   1481 SQFdtkltklrNELQDTNDKLITSD 1505
Cdd:TIGR01612 1150 AQI--------NDLEDVADKAISND 1166
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1778-2222 1.17e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1778 ETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTD 1857
Cdd:COG4913  224 FEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAE 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1858 LDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDT-NKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTD 1936
Cdd:COG4913  304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1937 KLRRDLTKAESVENELRKTIdiqsktsheyqllkdqllntQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVS 2016
Cdd:COG4913  384 ALRAEAAALLEALEEELEAL--------------------EEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLL 443

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2017 ELQRQLQDAnTEKNRVEDRFL---------------SVEKVVNTMRTT----------------ETDLRQQLETAKNEKR 2065
Cdd:COG4913  444 ALRDALAEA-LGLDEAELPFVgelievrpeeerwrgAIERVLGGFALTllvppehyaaalrwvnRLHLRGRLVYERVRTG 522

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2066 VATKELED--------------------LKRRLA------------QLENERRN---SSQLSDGW----KKEKITLL--- 2103
Cdd:COG4913  523 LPDPERPRldpdslagkldfkphpfrawLEAELGrrfdyvcvdspeELRRHPRAitrAGQVKGNGtrheKDDRRRIRsry 602

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2104 -------KKIELLENEKRRTDAAIRETALQREAIEKSLNAMEREnKELYKNCAQLQQQIAQ---------------LEME 2161
Cdd:COG4913  603 vlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQER-REALQRLAEYSWDEIDvasaereiaeleaelERLD 681

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529 2162 NGNRILELTNKQREEQERQLIRMRQEKGQIEKvienRERTHRNRIKQLEDQIAILRDQLDG 2222
Cdd:COG4913  682 ASSDDLAALEEQLEELEAELEELEEELDELKG----EIGRLEKELEQAEEELDELQDRLEA 738
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 618-1036 1.31e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 1.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    618 QLERKLKIAESQVK------EFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEK 691
Cdd:pfam05483  210 RLEMHFKLKEDHEKiqhleeEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    692 ARKFLEDELAKLQASFQKSSTDDaRKLRDEMDEHTNSI---QEEFKTRIDELNR-----------------RVENLLR-E 750
Cdd:pfam05483  290 KKDHLTKELEDIKMSLQRSMSTQ-KALEEDLQIATKTIcqlTEEKEAQMEELNKakaahsfvvtefeattcSLEELLRtE 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    751 NNRLKSEVNPLKDKYRDLE---NEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDD---LREKYDRVHTDNEKILGELEHA 824
Cdd:pfam05483  369 QQRLEKNEDQLKIITMELQkksSELEEMTKFKNNKEVELEELKKILAEDEKLLDEkkqFEKIAEELKGKEQELIFLLQAR 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    825 QKAAHLAEQQLKEIKIQRDDYQKQKDeharhlfDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISD-------YESQ 897
Cdd:pfam05483  449 EKEIHDLEIQLTAIKTSEEHYLKEVE-------DLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDmtlelkkHQED 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    898 INLLRRHNDELDTTIKGHQGKITHLENELHS-RSGEIEKLNDLNQRLQKEKQDILN----------QKLKLDGDVQALKE 966
Cdd:pfam05483  522 IINCKKQEERMLKQIENLEEKEMNLRDELESvREEFIQKGDEVKCKLDKSEENARSieyevlkkekQMKILENKCNNLKK 601

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    967 TIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDvNKQLEQDIRDLKE 1036
Cdd:pfam05483  602 QIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIID-NYQKEIEDKKISE 670
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 827-1059 1.49e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.49e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  827 AAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHND 906
Cdd:COG4942   14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  907 ELDTTIKGHQGKITHLENELHsRSGEIEKLNDLNQrlQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELV 986
Cdd:COG4942   94 ELRAELEAQKEELAELLRALY-RLGRQPPLALLLS--PEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  987 GKEARARDAANQQLSRANLLNKE-------LEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGA 1059
Cdd:COG4942  171 AERAELEALLAELEEERAALEALkaerqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 788-1537 1.57e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 1.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    788 YSDDIRRNIQKDLDDLREKYDRVHTDNEKILG-----ELEHAQKAAHLAEQQlKEIKIQRDDYQKQKDEHARhlfdIRHK 862
Cdd:pfam05483   61 YQEGLKDSDFENSEGLSRLYSKLYKEAEKIKKwkvsiEAELKQKENKLQENR-KIIEAQRKAIQELQFENEK----VSLK 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    863 LETEIKGRQDLEKNGARNNDELDKLRQT-------ISDYESQINLLRR----HNDELDTTIKGHQGKITHLEN---ELHS 928
Cdd:pfam05483  136 LEEEIQENKDLIKENNATRHLCNLLKETcarsaekTKKYEYEREETRQvymdLNNNIEKMILAFEELRVQAENarlEMHF 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    929 RSGE-IEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLN 1007
Cdd:pfam05483  216 KLKEdHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLT 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1008 KELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKggrisrdsttgtdggafgDRSSVADPSRTRGAAGSTVFVPAaed 1087
Cdd:pfam05483  296 KELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTE------------------EKEAQMEELNKAKAAHSFVVTEF--- 354

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1088 iesrgggEIDIPSSGDVIHGRDGRDGRDAGNRGTHTITNTKERIERIEKNILDRYHDDELVEHKirevndRWKRELERLE 1167
Cdd:pfam05483  355 -------EATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELK------KILAEDEKLL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1168 NEKDDLERRIREL---EDELSQIGRGNDKTEND-------ITELKRKHAAEIDKLKSDisaLHDKHLSDLDDEKEQYGKA 1237
Cdd:pfam05483  422 DEKKQFEKIAEELkgkEQELIFLLQAREKEIHDleiqltaIKTSEEHYLKEVEDLKTE---LEKEKLKNIELTAHCDKLL 498

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1238 VENlKSVEDDLRDKLNNLEKQLADSLNRENELEREKRdydeKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRS 1317
Cdd:pfam05483  499 LEN-KELTQEASDMTLELKKHQEDIINCKKQEERMLK----QIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEE 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1318 EAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLtsqvrHLEDELADTKGNLVQKEMDLESTQNRLRSLEdqhs 1397
Cdd:pfam05483  574 NARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEEL-----HQENKALKKKGSAENKQLNAYEIKVNKLELE---- 644

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1398 tLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEkerlQNAFREKTKQadHLN 1477
Cdd:pfam05483  645 -LASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAE----MVALMEKHKH--QYD 717

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1478 QLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQ 1537
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1162-1595 1.83e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 1.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1162 ELERLENEKDDLERRIRELEDELSQ----IGRGNDKTEN---DITEL------KRKHAAEIDK-LKSDISALHDKH--LS 1225
Cdd:PRK02224  308 DAEAVEARREELEDRDEELRDRLEEcrvaAQAHNEEAESlreDADDLeeraeeLREEAAELESeLEEAREAVEDRReeIE 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1226 DLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINslygQNQKIKDEWDDFRNDADKEI 1305
Cdd:PRK02224  388 ELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVE----EAEALLEAGKCPECGQPVEG 463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1306 QKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVndhtskvrDLTSQVRHLEDELADTKGNLVQKEMDLEST 1385
Cdd:PRK02224  464 SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLV--------EAEDRIERLEERREDLEELIAERRETIEEK 535

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1386 QNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLksaeDALKELKNSLSHAKTEKERLQNa 1465
Cdd:PRK02224  536 RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI----ESLERIRTLLAAIADAEDEIER- 610

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1466 FREKTKQADHLNQlasQFDTKLTKLRNELQDTNDKLitsDTER-NALRNELQKLSQELkfgnEQIQRKSDEYQTTIDDLA 1544
Cdd:PRK02224  611 LREKREALAELND---ERRERLAEKRERKRELEAEF---DEARiEEAREDKERAEEYL----EQVEEKLDELREERDDLQ 680

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 25151529  1545 HSHRVSEDSrLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSE 1595
Cdd:PRK02224  681 AEIGAVENE-LEELEELRERREALENRVEALEALYDEAEELESMYGDLRAE 730
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1143-2087 2.20e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 2.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1143 HDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELsqigrgndktenDITELKRKHAAEIDKLKSDIsalhdk 1222
Cdd:pfam02463  158 IEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQE------------LKLKEQAKKALEYYQLKEKL------ 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1223 hlsdldDEKEQYGKAVENLKSVED--DLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRND 1300
Cdd:pfam02463  220 ------ELEEEYLLYLDYLKLNEEriDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1301 ADKEiqkwktdaytVRSEAKALETTNTALKAQLQAANDRIDHLTKtvndHTSKVRDLTSQVRHLEDELADTKGNLVQKEM 1380
Cdd:pfam02463  294 EEEE----------LKSELLKLERRKVDDEEKLKESEKEKKKAEK----ELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1381 DLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKsaEDALKELKNSLSHAKTEKE 1460
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE--DLLKEEKKEELEILEEEEE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1461 RLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLsQELKFGNEQIQRKSDEYQTTI 1540
Cdd:pfam02463  438 SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL-EERSQKESKARSGLKVLLALI 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1541 DDLAHSHRVSEDSRLNALQELEArkyeiNDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSsaNRVINFHTFV 1620
Cdd:pfam02463  517 KDGVGGRIISAHGRLGDLGVAVE-----NYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARK--LRLLIPKLKL 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1621 DGGAGYVDGVpggtsvigggpsaqrsgayDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADF 1700
Cdd:pfam02463  590 PLKSIAVLEI-------------------DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1701 SSGRPGAASAGGRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLarmkkKTTETHTTINQKETR 1780
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKE-----ELKKLKLEAEELLAD 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1781 YRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLrtdldn 1860
Cdd:pfam02463  726 RVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ------ 799

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1861 ahtdIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLqiasfESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRR 1940
Cdd:pfam02463  800 ----EEELRALEEELKEEAELLEEEQLLIEQEEKIKEE-----ELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1941 DLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQ--NELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSEL 2018
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQklNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEK 950

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2019 QRQ-LQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRN 2087
Cdd:pfam02463  951 EENnKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1907-2087 2.22e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 2.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1907 RQILTEKI-KELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELN---- 1981
Cdd:COG4717   44 RAMLLERLeKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEklek 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1982 -----GANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRF----LSVEKVVNTMRTTETD 2052
Cdd:COG4717  124 llqllPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLeqlsLATEEELQDLAEELEE 203

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 25151529 2053 LRQQLETAKNEKRVATKELEDLKRRLAQLENERRN 2087
Cdd:COG4717  204 LQQRLAELEEELEEAQEELEELEEELEQLENELEA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 640-897 2.37e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  640 ADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQAsfqksstdDARKLR 719
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA--------ELAELE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  720 DEMDEhtnsIQEEFKTRIDELNRRVENLLR--ENNRLKSEVNPlkdkyrdleNEYNSTQRRieeketqIRYSDDIRRNIQ 797
Cdd:COG4942   90 KEIAE----LRAELEAQKEELAELLRALYRlgRQPPLALLLSP---------EDFLDAVRR-------LQYLKYLAPARR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  798 KDLDDLREKYDRVHTDNEKIlgELEHAQKAAHLAEQQlkeikIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNG 877
Cdd:COG4942  150 EQAEELRADLAELAALRAEL--EAERAELEALLAELE-----EERAALEALKAERQKLLARLEKELAELAAELAELQQEA 222

                        250       260
                 ....*....|....*....|
gi 25151529  878 ARNNDELDKLRQTISDYESQ 897
Cdd:COG4942  223 EELEALIARLEAEAAAAAER 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 779-1125 2.48e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.61  E-value: 2.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  779 IEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFd 858
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  859 irhkleteikgrqdleKNGaRNNDELDKL--RQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKL 936
Cdd:COG3883   97 ----------------RSG-GSVSYLDVLlgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  937 NDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQD 1016
Cdd:COG3883  160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1017 LKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEI 1096
Cdd:COG3883  240 AAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASGGSGGGSGGAGGVGSGGGA 319

                        330       340
                 ....*....|....*....|....*....
gi 25151529 1097 DIPSSGDVIHGRDGRDGRDAGNRGTHTIT 1125
Cdd:COG3883  320 GAVVGGASAGGGGGSGGGGGSSGGGSGGG 348
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1792-2212 2.68e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.28  E-value: 2.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1792 EEERRALESRLQSAKTLLRSQ-----EEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTdldnahTDIR 1866
Cdd:pfam15921  244 EDQLEALKSESQNKIELLLQQhqdriEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS------MYMR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1867 SLRDKEeqwdSSRFQLETKMRESdsdtnkyqlqiasfeseRQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDltkAE 1946
Cdd:pfam15921  318 QLSDLE----STVSQLRSELREA-----------------KRMYEDKIEELEKQLVLANSELTEARTERDQFSQE---SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1947 SVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNnrvSELQRQLQdan 2026
Cdd:pfam15921  374 NLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMK---SECQGQME--- 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2027 TEKNRVEDRFLSVEKVvntmrtteTDLRQQLETAKNEKRvatKELEDLKRRLAQLENERRNSSQLSDGwkkekitllkki 2106
Cdd:pfam15921  448 RQMAAIQGKNESLEKV--------SSLTAQLESTKEMLR---KVVEELTAKKMTLESSERTVSDLTAS------------ 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2107 elLENEKRRTDAAIRETALQREAIEKSLNAMER-ENKELYKNCAQLQQQIAQLEMENGNRILELTNKQRE-------EQE 2178
Cdd:pfam15921  505 --LQEKERAIEATNAEITKLRSRVDLKLQELQHlKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEnmtqlvgQHG 582

                          410       420       430
                   ....*....|....*....|....*....|....
gi 25151529   2179 RQLIRMRQEKGQIEKVIENReRTHRNRIKQLEDQ 2212
Cdd:pfam15921  583 RTAGAMQVEKAQLEKEINDR-RLELQEFKILKDK 615
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 508-974 2.74e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 2.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  508 EGDAELHKELMTKYEESIERnieLESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTR 587
Cdd:COG1196  301 EQDIARLEERRRELEERLEE---LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  588 SlspgktplppsEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDE 667
Cdd:COG1196  378 E-----------EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  668 AERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSST----------------------------------- 712
Cdd:COG1196  447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAArllllleaeadyegflegvkaalllaglrglagav 526

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  713 ----DDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENN--------------RLKSEVNPLKDKYRDLENEYNS 774
Cdd:COG1196  527 avliGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKagratflpldkiraRAALAAALARGAIGAAVDLVAS 606

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  775 TQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHAR 854
Cdd:COG1196  607 DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  855 HLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQG-----------KITHLE 923
Cdd:COG1196  687 RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEeealeelpeppDLEELE 766

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  924 NELHSRSGEIEKLNDLN-------QRLQKEKQDILNQKLKLDGDVQALKETIRKLENE 974
Cdd:COG1196  767 RELERLEREIEALGPVNllaieeyEELEERYDFLSEQREDLEEARETLEEAIEEIDRE 824
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1162-1530 3.71e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 55.52  E-value: 3.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1162 ELERLENEKDDLERRIRE----LEDELSQIGRGNDKTENDITELKRKHAAEIDKLKsdisaLHDKHLSDLDDEKEQYGKA 1237
Cdd:pfam05557   87 ALNKKLNEKESQLADAREviscLKNELSELRRQIQRAELELQSTNSELEELQERLD-----LLKAKASEAEQLRQNLEKQ 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1238 VENLKSVEDDLRDKLNNLEKQLADSLNREN---------ELEREK---RDYDEKINSLYGQNQKIKDEWDDFRNDADKEI 1305
Cdd:pfam05557  162 QSSLAEAEQRIKELEFEIQSQEQDSEIVKNskselaripELEKELerlREHNKHLNENIENKLLLKEEVEDLKRKLEREE 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1306 QkwktdaytVRSEAKALETTNTALKAQLQ-----------------AANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDEL 1368
Cdd:pfam05557  242 K--------YREEAATLELEKEKLEQELQswvklaqdtglnlrspeDLSRRIEQLQQREIVLKEENSSLTSSARQLEKAR 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1369 ADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSdankwrgELDAALRENDILKSNNTNMETDLT------RLKNRLKSAE 1442
Cdd:pfam05557  314 RELEQELAQYLKKIEDLNKKLKRHKALVRRLQR-------RVLLLTKERDGYRAILESYDKELTmsnyspQLLERIEEAE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1443 DALKELKNSLSHAKTekeRLQNAFREKTKQadhlNQLASQFDTKLTKLRNElQDTNDKLITSDtERNALRNELQKLSQEL 1522
Cdd:pfam05557  387 DMTQKMQAHNEEMEA---QLSVAEEELGGY----KQQAQTLERELQALRQQ-ESLADPSYSKE-EVDSLRRKLETLELER 457


                   ....*...
gi 25151529   1523 KFGNEQIQ 1530
Cdd:pfam05557  458 QRLREQKN 465
PTZ00121 PTZ00121
MAEBL; Provisional
 330-1009 4.11e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 4.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   330 EERRRSDEYRMQWENERQKSLSLED--ENDRLRREFERYANDSKDKEKTFINRERNLAQYLSDEQRKMLDLWTELQRVRK 407
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   408 QFSDLKTHTEEDldKQKAEFTR----AIRNVNNISRNAAFSAGAGDglglygLEDGGDVNRTTNNYEKVFIETIKRMNGT 483
Cdd:PTZ00121 1392 KADEAKKKAEED--KKKADELKkaaaAKKKADEAKKKAEEKKKADE------AKKKAEEAKKADEAKKKAEEAKKAEEAK 1463

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   484 GGAGSASSADLL----EELRKIRGGGSSEGDAELHKELMTKYEESIERNIEL----ESRGDDSQRKIAEL-EAELRRNRE 554
Cdd:PTZ00121 1464 KKAEEAKKADEAkkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAkkaeEAKKADEAKKAEEAkKADEAKKAE 1543

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   555 KLNEAQgALKKLHEMAQDSE-KNVDGTVSIKRTRSLSPGKTP-LPPSEALRAVRNTFRNKDNDIQQLERKLKIAESQVK- 631
Cdd:PTZ00121 1544 EKKKAD-ELKKAEELKKAEEkKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKa 1622

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   632 EFLNKFENADEARRRLDKQFADAKREISNLQKsvdEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSs 711
Cdd:PTZ00121 1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKK---AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA- 1698

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   712 tDDARKLrdemdehtnsiqEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRdlENEYNSTQRRIEEKEtqirysdd 791
Cdd:PTZ00121 1699 -EEAKKA------------EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE--EDKKKAEEAKKDEEE-------- 1755

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   792 iRRNIQKDLDDLREKYDRVHTDNEKILGE--LEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKG 869
Cdd:PTZ00121 1756 -KKKIAHLKKEEEKKAEEIRKEKEAVIEEelDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKE 1834

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   870 RQD-----------LEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHsrsgeieklnd 938
Cdd:PTZ00121 1835 VADsknmqleeadaFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIP----------- 1903

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529   939 lNQRLQKEKQDILNQKLKLDgdvQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKE 1009
Cdd:PTZ00121 1904 -NNNMAGKNNDIIDDKLDKD---EYIKRDAEETREEIIKISKKDMCINDFSSKFCDYMKDNISSGNCSDEE 1970
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 551-926 4.21e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 4.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    551 RNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIK-RTRSLSPGKTPLPPSE------ALRAVRNTFRNKDNDIQQLERKL 623
Cdd:TIGR00606  688 QTEAELQEFISDLQSKLRLAPDKLKSTESELKKKeKRRDEMLGLAPGRQSIidlkekEIPELRNKLQKVNRDIQRLKNDI 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    624 KIAESQVKEFLNKFENADEAR------RRLDKQFADAKREI---------SNLQKSVDEAERNSRRTDDKLRASEAErva 688
Cdd:TIGR00606  768 EEQETLLGTIMPEEESAKVCLtdvtimERFQMELKDVERKIaqqaaklqgSDLDRTVQQVNQEKQEKQHELDTVVSK--- 844

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    689 AEKARKFLEDELAKLQAsfQKSSTDDARKLRDEMDEHTNSIQEeFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDL 768
Cdd:TIGR00606  845 IELNRKLIQDQQEQIQH--LKSKTNELKSEKLQIGTNLQRRQQ-FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKD 921

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    769 ENEynsTQRRIEEKETQIRYSDDIRRNIQKDLDDLR------EKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQR 842
Cdd:TIGR00606  922 QQE---KEELISSKETSNKKAQDKVNDIKEKVKNIHgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINE 998

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    843 DDYQKQKDEHARHLFD-------IRHKLETEIKGRQDLEKN--GARNNDELDKLRQTISDYESQINLLRRHNDELDTTIK 913
Cdd:TIGR00606  999 DMRLMRQDIDTQKIQErwlqdnlTLRKRENELKEVEEELKQhlKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQK 1078

                          410
                   ....*....|...
gi 25151529    914 GHQGKITHLENEL 926
Cdd:TIGR00606 1079 GYEKEIKHFKKEL 1091
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1732-2216 4.30e-07

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 55.60  E-value: 4.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1732 IANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTT------INQKETRYRNIEDNLQDAEEERRALESrlqSA 1805
Cdd:pfam10174  187 IAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTkalqtvIEMKDTKISSLERNIRDLEDEVQMLKT---NG 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1806 KTLLRSQEEALKQRDEERRQ---MKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNA--HTDI--RSLRDKEE----- 1873
Cdd:pfam10174  264 LLHTEDREEEIKQMEVYKSHskfMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCkqHIEVlkESLTAKEQraail 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1874 --QWDSSRFQLETKmresDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENE 1951
Cdd:pfam10174  344 qtEVDALRLRLEEK----ESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAG 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1952 LRKTI-DIQSKTSHeyqllKDQLLNTQNELNGANNR-----KQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDA 2025
Cdd:pfam10174  420 LKERVkSLQTDSSN-----TDTALTTLEEALSEKERiierlKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2026 NTEKN--------------RVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKElEDLKRRLAQLENERRNSSQL 2091
Cdd:pfam10174  495 ESSLIdlkehasslassglKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTN-PEINDRIRLLEQEVARYKEE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2092 SDGWKKEKITLLKKIELLENEKRRTDAAIRE-------------------TALQREAIEKSLNAME---RENKELYKNCA 2149
Cdd:pfam10174  574 SGKAQAEVERLLGILREVENEKNDKDKKIAElesltlrqmkeqnkkvaniKHGQQEMKKKGAQLLEearRREDNLADNSQ 653

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529   2150 QLQQQIAQLEMENGNRILELTnKQR--------EEQERQLIRMRQE-KGQIEKVIENRERTHRNRIKQLEDQIAIL 2216
Cdd:pfam10174  654 QLQLEELMGALEKTRQELDAT-KARlsstqqslAEKDGHLTNLRAErRKQLEEILEMKQEALLAAISEKDANIALL 728
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1745-2197 4.53e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 55.57  E-value: 4.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1745 KIEKLEMERNELRDTLARMKKKTTethttinQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERR 1824
Cdd:pfam01576  132 KIKKLEEDILLLEDQNSKLSKERK-------LLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQ 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1825 QMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFE 1904
Cdd:pfam01576  205 ELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESER 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1905 SERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKtSHEYQL-------------LKD 1971
Cdd:pfam01576  285 AARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETR-SHEAQLqemrqkhtqaleeLTE 363

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1972 QLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTeknrvedRFLSVEKVVNTMRTTET 2051
Cdd:pfam01576  364 QLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQA-------RLSESERQRAELAEKLS 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2052 DLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIE 2131
Cdd:pfam01576  437 KLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVE 516

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529   2132 KSLNAMERENKELYKNCAQLQQQIAQLE--MENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIEN 2197
Cdd:pfam01576  517 RQLSTLQAQLSDMKKKLEEDAGTLEALEegKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDD 584
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1728-2127 4.64e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1728 GGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQ-KETRYRNIEDNLQDAEEERRALesrLQSAK 1806
Cdd:PRK03918  382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElKKAKGKCPVCGRELTEEHRKEL---LEEYT 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1807 TLLRSQEEALKQRDEERRQMKSKMVAAE--LQARGKEAQLRHLNEQLKNLRTDLDNahTDIRSLRDKEEQWdssrfqlet 1884
Cdd:PRK03918  459 AELKRIEKELKEIEEKERKLRKELRELEkvLKKESELIKLKELAEQLKELEEKLKK--YNLEELEKKAEEY--------- 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1885 kmRESDSDTNKYQLQIASFESErqilTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKA--ESVEnELRKTIDIQSKT 1962
Cdd:PRK03918  528 --EKLKEKLIKLKGEIKSLKKE----LEKLEELKKKLAELEKKLDELEEELAELLKELEELgfESVE-ELEERLKELEPF 600

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1963 SHEYQLLKdqllNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDanTEKNRVEDRFLSVEKV 2042
Cdd:PRK03918  601 YNEYLELK----DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRE 674

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2043 VntmrtteTDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLsdgwkkEKItlLKKIELLENEKRRTDAAIRE 2122
Cdd:PRK03918  675 L-------AGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKL------EKA--LERVEELREKVKKYKALLKE 739


                  ....*
gi 25151529  2123 TALQR 2127
Cdd:PRK03918  740 RALSK 744
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
474-867 4.92e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   474 IETIKRMNGTGGAGSASSADLLEELRKIRGGG---SSEGDAELHKELMTKYEESIERnieLESRGDDSQRKIAELEAELR 550
Cdd:PRK03918  407 ISKITARIGELKKEIKELKKAIEELKKAKGKCpvcGRELTEEHRKELLEEYTAELKR---IEKELKEIEEKERKLRKELR 483

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   551 RNREKLNEaQGALKKLHEMAqDSEKNVDGTVSIKRTRSLSPGktplppSEALRAVRNTFRNKDNDIQQLERKLKiaesQV 630
Cdd:PRK03918  484 ELEKVLKK-ESELIKLKELA-EQLKELEEKLKKYNLEELEKK------AEEYEKLKEKLIKLKGEIKSLKKELE----KL 551

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   631 KEFLNKFENADEARRRLDKQFADAKREISNLQ-KSVDEAERNSRRtddkLRASEAERVAAEKARKFLEDELAKLQasfqk 709
Cdd:PRK03918  552 EELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKE----LEPFYNEYLELKDAEKELEREEKELK----- 622

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   710 sstddarKLRDEMDEHTNSIQEEFKtRIDELNRRVENLLRENNrlksevnplKDKYRDLENEYNSTQRRIEEKETQIRYS 789
Cdd:PRK03918  623 -------KLEEELDKAFEELAETEK-RLEELRKELEELEKKYS---------EEEYEELREEYLELSRELAGLRAELEEL 685

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529   790 DDIRRNIQKDLDDLREKydrvhtdnekiLGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEI 867
Cdd:PRK03918  686 EKRREEIKKTLEKLKEE-----------LEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1791-2038 6.03e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 6.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1791 AEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLR- 1869
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRa 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1870 DKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFEserqiltekikELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVE 1949
Cdd:COG4942   98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFL-----------DAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1950 NELRKTIDiqsktshEYQLLKDQLLNTQNELNGANNRKQQLENELlnvRSEVRDYKQRVHDVNNRVSELQRQLQDANTEK 2029
Cdd:COG4942  167 AELEAERA-------ELEALLAELEEERAALEALKAERQKLLARL---EKELAELAAELAELQQEAEELEALIARLEAEA 236


                 ....*....
gi 25151529 2030 NRVEDRFLS 2038
Cdd:COG4942  237 AAAAERTPA 245
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 735-903 6.76e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 52.62  E-value: 6.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  735 TRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIrysDDIRRNIQKDlddlREKYDRVHTDN 814
Cdd:COG1579   17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI---EEVEARIKKY----EEQLGNVRNNK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  815 E--KILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEikgRQDLEKNGARNNDELDKLRQTIS 892
Cdd:COG1579   90 EyeALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEK---KAELDEELAELEAELEELEAERE 166

                        170
                 ....*....|...
gi 25151529  893 DYESQI--NLLRR 903
Cdd:COG1579  167 ELAAKIppELLAL 179
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1144-1535 7.28e-07

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 53.92  E-value: 7.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1144 DDELVEHKIREVNDRWkRELERL-----------ENEKDDLER---RIRELEDELSQIGRGNDKTENDITELKRKHAAei 1209
Cdd:pfam19220    4 RNELLRVRLGEMADRL-EDLRSLkadfsqliepiEAILRELPQaksRLLELEALLAQERAAYGKLRRELAGLTRRLSA-- 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1210 dkLKSDISALhDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSlygqnqk 1289
Cdd:pfam19220   81 --AEGELEEL-VARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQA------- 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1290 ikdewddfrndADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELA 1369
Cdd:pfam19220  151 -----------AEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLA 219

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1370 DTKG----NLVQKEMDLESTQNRLRSLEDQHSTLQSDAN---KWRGELDAALREND--ILKSNNTNMETDLTRlknrlKS 1440
Cdd:pfam19220  220 AEQAererAEAQLEEAVEAHRAERASLRMKLEALTARAAateQLLAEARNQLRDRDeaIRAAERRLKEASIER-----DT 294

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1441 AEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQ 1520
Cdd:pfam19220  295 LERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANR 374

                          410
                   ....*....|....*
gi 25151529   1521 ELKfgnEQIQRKSDE 1535
Cdd:pfam19220  375 RLK---EELQRERAE 386
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1788-2011 7.88e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 7.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1788 LQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERR--QMKSKMVAAELQARGKEAQLRHLNEQLKnlrtDLDNAHTDI 1865
Cdd:COG4913  612 LAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELE----RLDASSDDL 687

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1866 RSLRDKEEQWdssrfqletkmresdsdtnkyqlqiasfESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKA 1945
Cdd:COG4913  688 AALEEQLEEL----------------------------EAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529 1946 ES-VENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSE-VRDYKQRVHDV 2011
Cdd:COG4913  740 EDlARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADL 807
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1164-2143 7.92e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 7.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1164 ERLENEKDDLERRIRELEDELSQIgrgnDKTENDITELKrKHAAEIDKLKSDISALHDKHLSDLDDE-KEQYGKAVENLK 1242
Cdd:TIGR00606  241 KSYENELDPLKNRLKEIEHNLSKI----MKLDNEIKALK-SRKKQMEKDNSELELKMEKVFQGTDEQlNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1243 SVEDDLRDKLNNLEKqladsLNRE-NELEREKRDYDEKINSLYGQNQKIKDEWDDFrndaDKEIQKWKTdaytvRSEAKA 1321
Cdd:TIGR00606  316 EKERELVDCQRELEK-----LNKErRLLNQEKTELLVEQGRLQLQADRHQEHIRAR----DSLIQSLAT-----RLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1322 LE-------TTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLED 1394
Cdd:TIGR00606  382 FErgpfserQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIK 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1395 QHSTLQSDANKWRgELDAALRENDI---LKSNNTNMETDLTRLKNRLKSAEDALKELKN------SLSHAKTEKERLQNA 1465
Cdd:TIGR00606  462 ELQQLEGSSDRIL-ELDQELRKAERelsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKldqemeQLNHHTTTRTQMEML 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1466 FREKTKQADHLNQLASQFDTKLTKLrneLQDTNDKLITSDTernalrneLQKLSQELKFGNEQIQRKSDEYQtTIDDLAH 1545
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKSRHSDELTSL---LGYFPNKKQLEDW--------LHSKSKEINQTRDRLAKLNKELA-SLEQNKN 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1546 SHRVSEDSRLNALQELEARKYEIndltSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSsanrvinfhtfvdggag 1625
Cdd:TIGR00606  609 HINNELESKEEQLSSYEDKLFDV----CGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQ----------------- 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1626 YVDGVPGGTSviGGGPSAQRsgaydpssggvigsgisggpggsDFGREIEIGRGDSDQSDVAypRSVPfppsadfssgrp 1705
Cdd:TIGR00606  668 FITQLTDENQ--SCCPVCQR-----------------------VFQTEAELQEFISDLQSKL--RLAP------------ 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1706 gaasaggrviNNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIE 1785
Cdd:TIGR00606  709 ----------DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIM 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1786 DNLQDAEEerralesrLQSAKTLLRSQEEALKQRDEERRQMkskmvAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDI 1865
Cdd:TIGR00606  779 PEEESAKV--------CLTDVTIMERFQMELKDVERKIAQQ-----AAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1866 RSLRDKEEQWDSSRFQLETKMRESDSDtnkyQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDtdklrrDLTKA 1945
Cdd:TIGR00606  846 ELNRKLIQDQQEQIQHLKSKTNELKSE----KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ------DSPLE 915

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1946 ESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENEllnVRSEVRDYKQrvhDVNNRVSELQRQLQDA 2025
Cdd:TIGR00606  916 TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENK---IQDGKDDYLK---QKETELNTVNAQLEEC 989

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2026 NTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEkrvatKELEDLKRRLAQLENERRNSSQLSDgwKKEKITLLKK 2105
Cdd:TIGR00606  990 EKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRE-----NELKEVEEELKQHLKEMGQMQVLQM--KQEHQKLEEN 1062

                          970       980       990
                   ....*....|....*....|....*....|....*...
gi 25151529   2106 IELLENEKRRTDAAIRETALQREAIEKSLNAMERENKE 2143
Cdd:TIGR00606 1063 IDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE 1100
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1733-2210 8.75e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 8.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1733 ANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINqketryrNIEDNLQDAEEERRALESRLQSAKTllrsq 1812
Cdd:pfam15921  373 GNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITID-------HLRRELDDRNMEVQRLEALLKAMKS----- 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1813 eealkqrdEERRQMKSKMVAAElqarGKEAQLrhlnEQLKNLRTDLDNAHtdiRSLRDKEEQWDSSRFQLETKMRESDSD 1892
Cdd:pfam15921  441 --------ECQGQMERQMAAIQ----GKNESL----EKVSSLTAQLESTK---EMLRKVVEELTAKKMTLESSERTVSDL 501

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1893 TNKYQlqiasfESERQI--LTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELrktidiqSKTSHEYQLLK 1970
Cdd:pfam15921  502 TASLQ------EKERAIeaTNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQM-------AEKDKVIEILR 568

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1971 DQLLNtQNELNGANNR--------KQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKV 2042
Cdd:pfam15921  569 QQIEN-MTQLVGQHGRtagamqveKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2043 VNTMRTTETDLRQQLETAKNEKRVATKELEDLKRrlaqleNERRNSSQLSDGWKKEKITL---LKKIELLENEKRRTDAA 2119
Cdd:pfam15921  648 VKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR------NFRNKSEEMETTTNKLKMQLksaQSELEQTRNTLKSMEGS 721

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2120 IRETALQREAIEKSLNAMERENKELykncaQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIE---KVIE 2196
Cdd:pfam15921  722 DGHAMKVAMGMQKQITAKRGQIDAL-----QSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAgelEVLR 796

                          490
                   ....*....|....
gi 25151529   2197 NRERTHRNRIKQLE 2210
Cdd:pfam15921  797 SQERRLKEKVANME 810
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1255-1563 9.45e-07

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 54.13  E-value: 9.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1255 LEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQ 1334
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1335 AANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAAL 1414
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1415 RENDILKSNNTNMET-------DLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFD--- 1484
Cdd:pfam07888  192 KEFQELRNSLAQRDTqvlqlqdTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDrtq 271

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1485 TKLTKLRNELQDTNDKLITSD-----------TERNALRN-------ELQKLSQELKFGNEQIQRKSDEYQTTIDDLAH- 1545
Cdd:pfam07888  272 AELHQARLQAAQLTLQLADASlalregrarwaQERETLQQsaeadkdRIEKLSAELQRLEERLQEERMEREKLEVELGRe 351

                          330       340
                   ....*....|....*....|
gi 25151529   1546 --SHRVSEDSRLNALQELEA 1563
Cdd:pfam07888  352 kdCNRVQLSESRRELQELKA 371
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1731-2154 1.10e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLR 1810
Cdd:COG1196  289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1811 SQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESD 1890
Cdd:COG1196  369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1891 SDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKV----------QDMKDDTDKLRRDLTKAESVENELRKTIDIQS 1960
Cdd:COG1196  449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELaeaaarllllLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1961 KTSHEY-----------------------------QLLKDQLLN----------TQNELNGANNRKQQLENELLNVRSEV 2001
Cdd:COG1196  529 LIGVEAayeaaleaalaaalqnivveddevaaaaiEYLKAAKAGratflpldkiRARAALAAALARGAIGAAVDLVASDL 608

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2002 RDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTM-------RTTETDLRQQLETAKNEKRVATKELEDL 2074
Cdd:COG1196  609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGeggsaggSLTGGSRRELLAALLEAEAELEELAERL 688

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2075 KRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQ 2154
Cdd:COG1196  689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1161-1612 1.36e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1161 RELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHA----AEIDKLKSDISALH-------------DKH 1223
Cdd:COG4913  288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgnggDRLEQLEREIERLEreleererrrarlEAL 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1224 LSDLD----DEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRN 1299
Cdd:COG4913  368 LAALGlplpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1300 DADKEIQKWKTDAY------TVRSEAK----ALETT--NTAL-----KAQLQAANDRIDHLTKTVNDHTSKVRDLTS--- 1359
Cdd:COG4913  448 ALAEALGLDEAELPfvgeliEVRPEEErwrgAIERVlgGFALtllvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPdpe 527

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1360 QVRHLEDELA---DTKGN--------LVQKEMDLESTQNrLRSLEDQH----STLQSDANKWRGELDA--ALRENDILKS 1422
Cdd:COG4913  528 RPRLDPDSLAgklDFKPHpfrawleaELGRRFDYVCVDS-PEELRRHPraitRAGQVKGNGTRHEKDDrrRIRSRYVLGF 606

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1423 NNtnmetdltrlKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQF---------DTKLTKLRNE 1493
Cdd:COG4913  607 DN----------RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSwdeidvasaEREIAELEAE 676

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1494 LQD---TNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHS----HRVSEDSRLNALQELEARKY 1566
Cdd:COG4913  677 LERldaSSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELqdrlEAAEDLARLELRALLEERFA 756

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 25151529 1567 EINDltsrlDSTEQRL-ATLQQDYIKADSERDILSDALRRFQSSANR 1612
Cdd:COG4913  757 AALG-----DAVERELrENLEERIDALRARLNRAEEELERAMRAFNR 798
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1782-1991 1.43e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.87  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1782 RNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALkqrdeERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNA 1861
Cdd:COG3206  164 QNLELRREEARKALEFLEEQLPELRKELEEAEAAL-----EEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1862 HTDIRSLRDKEEQWDSSRFQLetkmrESDSDTNKYQLQIASFESERQILT--------------EKIKELDGALR-LSDS 1926
Cdd:COG3206  239 EARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSarytpnhpdvialrAQIAALRAQLQqEAQR 313

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1927 KVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLE 1991
Cdd:COG3206  314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
530-1018 1.55e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 1.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  530 ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEmaqdseknvdgtvsikrtrslspgktplppsealravrntf 609
Cdd:COG4717   54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAE----------------------------------------- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  610 rnKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLD--KQFADAKREISNLQKSVDEaernsrrtddkLRASEAERV 687
Cdd:COG4717   93 --LQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEE-----------LEERLEELR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  688 AAEKARKFLEDELAKLQAsfqksstdDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRD 767
Cdd:COG4717  160 ELEEELEELEAELAELQE--------ELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  768 LENEYNSTQ--RRIEEKETQIR----------YSDDIRRNIQKDLD----------DLREKYDRVHTDNEKILGELEHAQ 825
Cdd:COG4717  232 LENELEAAAleERLKEARLLLLiaaallallgLGGSLLSLILTIAGvlflvlgllaLLFLLLAREKASLGKEAEELQALP 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  826 KAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEK--NGARNNDELDKLRQ-----TISDYESQI 898
Cdd:COG4717  312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAeagveDEEELRAAL 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  899 NLLRRHNDEldttikghQGKITHLENELHSRSGEIEKLNDLNQ--RLQKEKQDILNQKLKLDGDVQALKETIRKLENELE 976
Cdd:COG4717  392 EQAEEYQEL--------KEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELE 463

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*...
gi 25151529  977 KLRNENK------ELVGKEARARDAAnQQLSRANLLNKELEDTKQDLK 1018
Cdd:COG4717  464 QLEEDGElaellqELEELKAELRELA-EEWAALKLALELLEEAREEYR 510
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1122-1586 1.70e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.69  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1122 HTITNTKERIERIEKNILDRYH-DDELVEHKIREvndrwKRELERLENEKDDLERRIRELEDELSQIgrgNDKTENDITE 1200
Cdd:pfam12128  241 PEFTKLQQEFNTLESAELRLSHlHFGYKSDETLI-----ASRQEERQETSAELNQLLRTLDDQWKEK---RDELNGELSA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1201 LKrkhaAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDlrdkLNNLEKQLADSLNRENELERE-------- 1272
Cdd:pfam12128  313 AD----AAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSE----LENLEERLKALTGKHQDVTAKynrrrski 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1273 KRDYDEKINSLYGQNQKIKDEWD---------------DFRNDADKEIQKWKTDAYTVRSEAKALE------TTNTALKA 1331
Cdd:pfam12128  385 KEQNNRDIAGIKDKLAKIREARDrqlavaeddlqalesELREQLEAGKLEFNEEEYRLKSRLGELKlrlnqaTATPELLL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1332 QLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQ--------HSTLQSDA 1403
Cdd:pfam12128  465 QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtlLHFLRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1404 NKWRGEL-----DAALRENDILKSNNTNM---ETDLTRLKNRLKSAE-----DALKELKNSLSHAKTEKERLQNAFREKT 1470
Cdd:pfam12128  545 PDWEQSIgkvisPELLHRTDLDPEVWDGSvggELNLYGVKLDLKRIDvpewaASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1471 KQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQK-LSQELKFGNEQIQRKSDEYQTTIDDL-AHSHR 1548
Cdd:pfam12128  625 EQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHqAWLEE 704

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 25151529   1549 VSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQ 1586
Cdd:pfam12128  705 QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARR 742
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1779-2222 1.71e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1779 TRYRNIEDNLQ--DAEEER-RALESRLqSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKE-----AQLRHLNEQ 1850
Cdd:PRK02224  150 DRQDMIDDLLQlgKLEEYReRASDARL-GVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESElaeldEEIERYEEQ 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1851 LKNLRTDLDNAHTDIRSLRDKEEQWDSsrfqLETKMRESDSDtnkyqlqIASFESERQILTEKIKELDGAL--------- 1921
Cdd:PRK02224  229 REQARETRDEADEVLEEHEERREELET----LEAEIEDLRET-------IAETEREREELAEEVRDLRERLeeleeerdd 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1922 RLSDSKVQDMKDDTDKLRRDL--TKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRS 1999
Cdd:PRK02224  298 LLAEAGLDDADAEAVEARREEleDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEARE 377

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2000 EVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATK---------- 2069
Cdd:PRK02224  378 AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpec 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2070 ------------------ELEDLKRRLAQLENERRNssqlsdgwKKEKITLLKkiELLENEKRRTDAAIRETALQREAIE 2131
Cdd:PRK02224  458 gqpvegsphvetieedreRVEELEAELEDLEEEVEE--------VEERLERAE--DLVEAEDRIERLEERREDLEELIAE 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2132 KSLNAMERENKELYKNCAQLQQQIAQLEMEngnrilELTNKQREEQERQLIRMRQEKGQIEKVIENRERThrNRIKQLED 2211
Cdd:PRK02224  528 RRETIEEKRERAEELRERAAELEAEAEEKR------EAAAEAEEEAEEAREEVAELNSKLAELKERIESL--ERIRTLLA 599

                         490
                  ....*....|.
gi 25151529  2212 QIAILRDQLDG 2222
Cdd:PRK02224  600 AIADAEDEIER 610
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 736-993 1.75e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  736 RIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKydrvhtdne 815
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--------- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  816 kilgelehaqkaahlAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYE 895
Cdd:COG4942   92 ---------------IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  896 SQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENEL 975
Cdd:COG4942  157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                        250
                 ....*....|....*...
gi 25151529  976 EKLRNENKELVGKEARAR 993
Cdd:COG4942  237 AAAAERTPAAGFAALKGK 254
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1739-1916 2.02e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.46  E-value: 2.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1739 LQSLLNKIEKLEMERNELRDTLARMKKKttethttINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQ 1818
Cdd:COG1579   12 LQELDSELDRLEHRLKELPAELAELEDE-------LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1819 -RDE-ERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDkeeqwdssrfQLETKMRESDSDTNKY 1896
Cdd:COG1579   85 vRNNkEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEA----------ELEEKKAELDEELAEL 154

                        170       180
                 ....*....|....*....|
gi 25151529 1897 QLQIASFESERQILTEKIKE 1916
Cdd:COG1579  155 EAELEELEAEREELAAKIPP 174
mukB PRK04863
chromosome partition protein MukB;
1331-1589 2.05e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.42  E-value: 2.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1331 AQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLE-------------------------DELADTKGNLVQKEMDLEST 1385
Cdd:PRK04863  837 AELRQLNRRRVELERALADHESQEQQQRSQLEQAKeglsalnrllprlnlladetladrvEEIREQLDEAEEAKRFVQQH 916

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1386 QNRLRSLEDQHSTLQSDAnkwrgeldaalRENDILKSNNTNMETDLTRLKNRLksaeDALKELKNSLSHAK--------T 1457
Cdd:PRK04863  917 GNALAQLEPIVSVLQSDP-----------EQFEQLKQDYQQAQQTQRDAKQQA----FALTEVVQRRAHFSyedaaemlA 981

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1458 EKERLQNAFREKTKQADhlnQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQEL-KFG-------NEQI 1529
Cdd:PRK04863  982 KNSDLNEKLRQRLEQAE---QERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELqDLGvpadsgaEERA 1058

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1530 QRKSDEyqttIDDLAHSHRvsedSRLNALQElearkyEINDLTSRLDSTEQRLATLQQDY 1589
Cdd:PRK04863 1059 RARRDE----LHARLSANR----SRRNQLEK------QLTFCEAEMDNLTKKLRKLERDY 1104
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1157-1617 2.13e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 2.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1157 DRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHAAEIDKLKSDISALHDKhLSDLDDEKEQYGK 1236
Cdd:COG4913  341 EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA-LAEAEAALRDLRR 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1237 AVENLKSVEDDLRDKLNNLE-------KQLADSLN-RENEL--------------------ER-----------EKRDYD 1277
Cdd:COG4913  420 ELRELEAEIASLERRKSNIParllalrDALAEALGlDEAELpfvgelievrpeeerwrgaiERvlggfaltllvPPEHYA 499

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1278 ---EKINSLYGQN----QKIKDEWDDFRND-------------ADKEIQKW-------KTDAYTVRSEAkALETTNTALK 1330
Cdd:COG4913  500 aalRWVNRLHLRGrlvyERVRTGLPDPERPrldpdslagkldfKPHPFRAWleaelgrRFDYVCVDSPE-ELRRHPRAIT 578

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1331 AQLQ--------AANDRIDHLTKTV--NDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLE--DQHST 1398
Cdd:COG4913  579 RAGQvkgngtrhEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSW 658

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1399 LQSDANKWRGELDAALRENDILKSNNtnmeTDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHL-N 1477
Cdd:COG4913  659 DEIDVASAEREIAELEAELERLDASS----DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELqD 734

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1478 QLASQFDTKLTKLRNELQDTNDKLITSDTE---RNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDS- 1553
Cdd:COG4913  735 RLEAAEDLARLELRALLEERFAAALGDAVErelRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESl 814

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529 1554 -----RLNALQE--LEARKYEINDLtsRLDSTEQRLATLQQDYikADSERDI------LSDALRRFQSSANRVINFH 1617
Cdd:COG4913  815 peylaLLDRLEEdgLPEYEERFKEL--LNENSIEFVADLLSKL--RRAIREIkeridpLNDSLKRIPFGPGRYLRLE 887
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 763-996 2.16e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  763 DKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQR 842
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  843 DDYQKQKDEHARHLFDIrhkleteikGRQDLEKNGARNNDELDKLR-----QTISDY-ESQINLLRRHNDELDTTIKGHQ 916
Cdd:COG4942  100 EAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRrlqylKYLAPArREQAEELRADLAELAALRAELE 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  917 GKITHLENELHSRSGEIEKLndlnQRLQKEKQDILNQklkLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAA 996
Cdd:COG4942  171 AERAELEALLAELEEERAAL----EALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1326-1587 2.48e-06

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 52.38  E-value: 2.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1326 NTALKAQLQAANDRIDHLtktvndhtskvRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLqsdank 1405
Cdd:pfam19220    5 NELLRVRLGEMADRLEDL-----------RSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKL------ 67

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1406 wRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQlasqfdt 1485
Cdd:pfam19220   68 -RRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEE------- 139

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1486 KLTKLRNELQDTNDKLITSDTERNALRNELQKLSQEL--------KFGNE--QIQRKSDEYQTTIDdlAHSHRVSE-DSR 1554
Cdd:pfam19220  140 ENKALREEAQAAEKALQRAEGELATARERLALLEQENrrlqalseEQAAElaELTRRLAELETQLD--ATRARLRAlEGQ 217

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 25151529   1555 LNALQ------------ELEARKYEINDLTSRLDSTEQRLATLQQ 1587
Cdd:pfam19220  218 LAAEQaereraeaqleeAVEAHRAERASLRMKLEALTARAAATEQ 262
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 854-999 2.61e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 2.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  854 RHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLEN--ELHSRSG 931
Cdd:COG1579   17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEYEALQK 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  932 EIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQ 999
Cdd:COG1579   97 EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1776-2144 2.69e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.87  E-value: 2.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1776 QKETRYRNIEDNLQDAEEERRALESRLQsAKTLLRSQEEALKQRDEERRQmKSKMVAAELQARGKEAQLRhlNEQLKNLR 1855
Cdd:pfam01576   23 KAESELKELEKKHQQLCEEKNALQEQLQ-AETELCAEAEEMRARLAARKQ-ELEEILHELESRLEEEEER--SQQLQNEK 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1856 TDLDNAHTDIRSLRDKEEQwDSSRFQLE-----TKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQD 1930
Cdd:pfam01576   99 KKMQQHIQDLEEQLDEEEA-ARQKLQLEkvtteAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKS 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1931 MKDDTDK-------LRRDLTKAESVENELRK--------TIDIQSKTSHEYQL---LKDQLLNTQNELNGANNRKQQLEN 1992
Cdd:pfam01576  178 LSKLKNKheamisdLEERLKKEEKGRQELEKakrklegeSTDLQEQIAELQAQiaeLRAQLAKKEEELQAALARLEEETA 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1993 ELLNVRSEVRdykqrvhDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRtteTDLRQQLETAKNEKRVATK--- 2069
Cdd:pfam01576  258 QKNNALKKIR-------ELEAQISELQEDLESERAARNKAEKQRRDLGEELEALK---TELEDTLDTTAAQQELRSKreq 327

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   2070 ELEDLKRRLAqlENERRNSSQLSDGWKKEKITLLKKIELLENEKRrtdaairetalQREAIEKSLNAMERENKEL 2144
Cdd:pfam01576  328 EVTELKKALE--EETRSHEAQLQEMRQKHTQALEELTEQLEQAKR-----------NKANLEKAKQALESENAEL 389
PRK11281 PRK11281
mechanosensitive channel MscK;
1325-1612 3.07e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.99  E-value: 3.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1325 TNTALKAQLQAANDRIDHltkTVNDHTSkVRDLTSQVRHLeDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDAn 1404
Cdd:PRK11281   37 TEADVQAQLDALNKQKLL---EAEDKLV-QQDLEQTLALL-DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDN- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1405 kwrgelDAALREnDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREktkqadhlNQlasqfd 1484
Cdd:PRK11281  111 ------DEETRE-TLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYA--------NS------ 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1485 TKLTKLRNELQDTND-KLITSDTERNALRNELQKLSQELKF------GNEQIQrksDEYQTTIDDLAHSHRVSEdSRLNA 1557
Cdd:PRK11281  170 QRLQQIRNLLKGGKVgGKALRPSQRVLLQAEQALLNAQNDLqrksleGNTQLQ---DLLQKQRDYLTARIQRLE-HQLQL 245

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 25151529  1558 LQELearkyeINDltSRLDSTEQRLATLQQdyikADSERDILSDALRRFQSSANR 1612
Cdd:PRK11281  246 LQEA------INS--KRLTLSEKTVQEAQS----QDEAARIQANPLVAQELEINL 288
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1146-1485 3.61e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 52.20  E-value: 3.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1146 ELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQigrgndkTENDITELKRKHaaeidklkSDISALHDKHLS 1225
Cdd:pfam07888   51 EAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQ-------SREKHEELEEKY--------KELSASSEELSE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1226 DLDDEKEQYGKAVENLKSVEDDLRD----------KLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWD 1295
Cdd:pfam07888  116 EKDALLAQRAAHEARIRELEEDIKTltqrvleretELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1296 DFRN---DADKEIQKWKTDAYTVR---SEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELA 1369
Cdd:pfam07888  196 ELRNslaQRDTQVLQLQDTITTLTqklTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELH 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1370 DTKGNLVQ-----KEMDLESTQNRLRSLEDQHSTLQS-DANKWRGE--------LDAALRENdilKSNNTNMETDLTRLK 1435
Cdd:pfam07888  276 QARLQAAQltlqlADASLALREGRARWAQERETLQQSaEADKDRIEklsaelqrLEERLQEE---RMEREKLEVELGREK 352

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 25151529   1436 --NRLKSAEDA--LKELKNSLSHAKTEKERLQNafrEKTKQADHLNQLASQFDT 1485
Cdd:pfam07888  353 dcNRVQLSESRreLQELKASLRVAQKEKEQLQA---EKQELLEYIRQLEQRLET 403
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
510-896 3.69e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   510 DAELHKELMTKYEESIErniELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGT-VSIKRTRS 588
Cdd:PRK02224  336 AAQAHNEEAESLREDAD---DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDApVDLGNAED 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   589 LspgktplppSEALRAVRNTFRNKDNDiqqLERKLKIAESQVKE---------------------FLNKFENADEARRRL 647
Cdd:PRK02224  413 F---------LEELREERDELREREAE---LEATLRTARERVEEaealleagkcpecgqpvegspHVETIEEDRERVEEL 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   648 DKQFADAKREISNLQKSVDEAE------------RNSRRTDDKLRASEAERVAAEKAR-KFLEDELAKLQASFQKSStDD 714
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEdlveaedrierlEERREDLEELIAERRETIEEKRERaEELRERAAELEAEAEEKR-EA 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   715 ARKLRDEMDEHTNSIQeEFKTRIDELNRRVENLlrenNRLKSEVNPLKDKYRDLEneynstqrRIEEKETQIRYSDDIRR 794
Cdd:PRK02224  560 AAEAEEEAEEAREEVA-ELNSKLAELKERIESL----ERIRTLLAAIADAEDEIE--------RLREKREALAELNDERR 626

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   795 niqkdlDDLREKYDRVHtdnekilgELEHAQKAAHLAEqqLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLE 874
Cdd:PRK02224  627 ------ERLAEKRERKR--------ELEAEFDEARIEE--AREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL 690

                         410       420
                  ....*....|....*....|..
gi 25151529   875 KNGARNNDELDKLRQTISDYES 896
Cdd:PRK02224  691 EELEELRERREALENRVEALEA 712
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1774-2221 3.83e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 3.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1774 INQKETRYRNIEDNLQDAEEERRALESRLQSAKTLL----RSQEE---ALKQRDEERRQMKSKMVAAELQARGKEAQLRH 1846
Cdd:pfam01576  491 LRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLsdmkKKLEEdagTLEALEEGKKRLQRELEALTQQLEEKAAAYDK 570

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1847 LNEQLKNLRTDLDNAHTDIRSLRD----------------KEEQWDSSRFQLETKMRESDSdtNKYQLQIASFESERQIL 1910
Cdd:pfam01576  571 LEKTKNRLQQELDDLLVDLDHQRQlvsnlekkqkkfdqmlAEEKAISARYAEERDRAEAEA--REKETRALSLARALEEA 648

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1911 TEKIKELDGALRLSDSKVQDM---KDDTDKLRRDLTKA---------------ESVENELRKTIDIQSKTSHEYQLLKDQ 1972
Cdd:pfam01576  649 LEAKEELERTNKQLRAEMEDLvssKDDVGKNVHELERSkraleqqveemktqlEELEDELQATEDAKLRLEVNMQALKAQ 728

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1973 L---LNTQNELNgaNNRKQQLENELLNVRSEVRD-YKQRVHDVNNR------VSELQRQLQDANteKNRVEdrflsVEKV 2042
Cdd:pfam01576  729 FerdLQARDEQG--EEKRRQLVKQVRELEAELEDeRKQRAQAVAAKkkleldLKELEAQIDAAN--KGREE-----AVKQ 799

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2043 VNTMRTTETDLRQQLETAK------------NEKRVATKELE--DLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIEL 2108
Cdd:pfam01576  800 LKKLQAQMKDLQRELEEARasrdeilaqskeSEKKLKNLEAEllQLQEDLAASERARRQAQQERDELADEIASGASGKSA 879

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2109 LENEKRRTDAAIreTALQREAIEKSLNaMERENKELYKncAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEK 2188
Cdd:pfam01576  880 LQDEKRRLEARI--AQLEEELEEEQSN-TELLNDRLRK--STLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKL 954

                          490       500       510
                   ....*....|....*....|....*....|...
gi 25151529   2189 GQIEKVIENRertHRNRIKQLEDQIAILRDQLD 2221
Cdd:pfam01576  955 QEMEGTVKSK---FKSSIAALEAKIAQLEEQLE 984
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1224-1444 3.87e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1224 LSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADK 1303
Cdd:COG4942   29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1304 EIQKwktdAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLE 1383
Cdd:COG4942  109 LLRA----LYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529 1384 STQNRLRSLEDQHSTLQSDANKWRGELDAALREndiLKSNNTNMETDLTRLKNRLKSAEDA 1444
Cdd:COG4942  185 EERAALEALKAERQKLLARLEKELAELAAELAE---LQQEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1788-2241 4.41e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.08  E-value: 4.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1788 LQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGK--EAQLRHLNEQLKNLRTDLDNAHTDI 1865
Cdd:COG4717   83 AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEalEAELAELPERLEELEERLEELRELE 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1866 RSLRDKEEQWDSSRFQLETKMRESDSDTNKyqlQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKA 1945
Cdd:COG4717  163 EELEELEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA 239

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1946 ESVE--NELRKTIDIQSkTSHEYQLLKDQLLNTQNELNGAnnrkQQLENELLNVRSEVRDYKQRVHdvNNRVSELQRQLQ 2023
Cdd:COG4717  240 ALEErlKEARLLLLIAA-ALLALLGLGGSLLSLILTIAGV----LFLVLGLLALLFLLLAREKASL--GKEAEELQALPA 312

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2024 DANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRvatkELEDLKRRLAQLENERRNSSQLSDGWKKEKITLL 2103
Cdd:COG4717  313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR----EAEELEEELQLEELEQEIAALLAEAGVEDEEELR 388

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2104 KKIELLEnekrrtdaairetalQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENgnRILELtNKQREEQERQLIR 2183
Cdd:COG4717  389 AALEQAE---------------EYQELKEELEELEEQLEELLGELEELLEALDEEELEE--ELEEL-EEELEELEEELEE 450

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2184 MRQEKGQIEkvienrerthrNRIKQLE--DQIAILRDQLDGERRRRREYVDRSMVNDIGR 2241
Cdd:COG4717  451 LREELAELE-----------AELEQLEedGELAELLQELEELKAELRELAEEWAALKLAL 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1366-1613 4.41e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 4.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1366 DELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDAL 1445
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1446 KELKNSLShaktekERLQNAFRekTKQADHLNQLASQFD-TKLTKLRNELQDTNDklitsdtERNALRNELQKLSQELKF 1524
Cdd:COG4942  100 EAQKEELA------ELLRALYR--LGRQPPLALLLSPEDfLDAVRRLQYLKYLAP-------ARREQAEELRADLAELAA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1525 GNEQIQRKSDEYQTTIDDLahshrvsEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDyikADSERDILSDALR 1604
Cdd:COG4942  165 LRAELEAERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQE---AEELEALIARLEA 234


                 ....*....
gi 25151529 1605 RFQSSANRV 1613
Cdd:COG4942  235 EAAAAAERT 243
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1151-1588 4.54e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 52.03  E-value: 4.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1151 KIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHAAEIDKLKSDISALHdkHL-SDLDD 1229
Cdd:pfam05483  223 KIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKD--HLtKELED 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1230 EKEQYGKAVENLKSVEDDLRdklnnLEKQLADSLNRENELEREkrdydekinslygqnqkikdewddfrndadkEIQKWK 1309
Cdd:pfam05483  301 IKMSLQRSMSTQKALEEDLQ-----IATKTICQLTEEKEAQME-------------------------------ELNKAK 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1310 TDAYTVRSEAKA----LETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLEST 1385
Cdd:pfam05483  345 AAHSFVVTEFEAttcsLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEK 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1386 qnrlRSLEDQHSTLQSDANKWRGELDAalRENDIlksnnTNMETDLTRLKNRLKSAEDALKELKNSLshaktEKERLQNA 1465
Cdd:pfam05483  425 ----KQFEKIAEELKGKEQELIFLLQA--REKEI-----HDLEIQLTAIKTSEEHYLKEVEDLKTEL-----EKEKLKNI 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1466 frEKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQ-------ELKFGNEQIQRKSDEYQT 1538
Cdd:pfam05483  489 --ELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEkemnlrdELESVREEFIQKGDEVKC 566

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 25151529   1539 TIDDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQD 1588
Cdd:pfam05483  567 KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQE 616
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1269-1611 4.99e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 52.13  E-value: 4.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1269 LEREKRDYDEKINSLYGQNQKIKDEwddfRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVN 1348
Cdd:pfam10174  245 LERNIRDLEDEVQMLKTNGLLHTED----REEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1349 DHTSKV----RDLTSQVRH---LEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILK 1421
Cdd:pfam10174  321 DCKQHIevlkESLTAKEQRaaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1422 SNNTNM-------ETDLTRLKNRLKSAED-------ALKELKNSLSHAKTEKERLQNAF----REKTKQADHLNQLASQF 1483
Cdd:pfam10174  401 KKIENLqeqlrdkDKQLAGLKERVKSLQTdssntdtALTTLEEALSEKERIIERLKEQReredRERLEELESLKKENKDL 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1484 DTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNAlqelea 1563
Cdd:pfam10174  481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNP------ 554

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 25151529   1564 rkyeinDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSAN 1611
Cdd:pfam10174  555 ------EINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKN 596
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1123-1339 5.53e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 5.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1123 TITNTKERIERIEKNILDRYHDDELVEHKIREVNDrwkrELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELK 1202
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1203 RKHAAEIDKLKSDISA-------------LHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENEL 1269
Cdd:COG4942   97 AELEAQKEELAELLRAlyrlgrqpplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1270 EREKRDYDEKINSLygqnQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDR 1339
Cdd:COG4942  177 EALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1736-2144 5.70e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 5.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1736 EGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEA 1815
Cdd:pfam01576  200 EKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQED 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1816 LkqrdeerrqmkskmvAAELQARGK-EAQLRHLNEQLKNLRTDLD------NAHTDIRSLRDKEEQWDSSRFQLETKMRE 1888
Cdd:pfam01576  280 L---------------ESERAARNKaEKQRRDLGEELEALKTELEdtldttAAQQELRSKREQEVTELKKALEEETRSHE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1889 SDS-----------DTNKYQLQIA-----SFESERQILTEKIKELDGALRLsdskVQDMKDDTDKLRRdltKAESVENEL 1952
Cdd:pfam01576  345 AQLqemrqkhtqalEELTEQLEQAkrnkaNLEKAKQALESENAELQAELRT----LQQAKQDSEHKRK---KLEGQLQEL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1953 rktidiQSKTSheyqllkdqllNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRV 2032
Cdd:pfam01576  418 ------QARLS-----------ESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEE 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2033 EDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLkrrlaqlenerrnSSQLSDgWKKEKITLLKKIELLENE 2112
Cdd:pfam01576  481 TRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL-------------QAQLSD-MKKKLEEDAGTLEALEEG 546

                          410       420       430
                   ....*....|....*....|....*....|..
gi 25151529   2113 KRRTDAAIRETALQREAIEKSLNAMERENKEL 2144
Cdd:pfam01576  547 KKRLQRELEALTQQLEEKAAAYDKLEKTKNRL 578
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 530-688 6.37e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 6.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  530 ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDgTVSIKRTRSlspgktplppSEALRAVRNT- 608
Cdd:COG1579   21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIE-EVEARIKKY----------EEQLGNVRNNk 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  609 -FRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERV 687
Cdd:COG1579   90 eYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169


                 .
gi 25151529  688 A 688
Cdd:COG1579  170 A 170
PTZ00121 PTZ00121
MAEBL; Provisional
 1786-2235 6.46e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 6.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1786 DNLQDAEEERRALESRLQSAKtllRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRhlnEQLKNLRTDLDNAHTDI 1865
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAK---KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKA---AAAKKKADEAKKKAEEK 1430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1866 RSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSdSKVQDMKDDTDKLRRDlTKA 1945
Cdd:PTZ00121 1431 KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK-KKAEEAKKKADEAKKA-AEA 1508

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1946 ESVENELRKTidiqSKTSHEYQLLKDQLLNTQNELNGANNRKQQLE---NELLNVRSEVRDYKQRVHDVNNRVSELQRQL 2022
Cdd:PTZ00121 1509 KKKADEAKKA----EEAKKADEAKKAEEAKKADEAKKAEEKKKADElkkAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2023 QDANTEKNRVEDRFLSVEKVvNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITL 2102
Cdd:PTZ00121 1585 EAKKAEEARIEEVMKLYEEE-KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2103 LKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENK--ELYKNCAQLQQQIAQ---LEMENGNRILELtNKQREEQ 2177
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKaeELKKKEAEEKKKAEElkkAEEENKIKAEEA-KKEAEED 1742

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  2178 ERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQLDGERRRRREYVDRSM 2235
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI 1800
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 846-1537 6.96e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 6.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    846 QKQKDEHARHLFDIRHKleteikgrQDLEKNGArnndELDKLRQTISDYESQINllrrhndELDTTIKGHQGKITHLENE 925
Cdd:pfam12128  217 RLNRQQVEHWIRDIQAI--------AGIMKIRP----EFTKLQQEFNTLESAEL-------RLSHLHFGYKSDETLIASR 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    926 LHSRSgeiEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENK--ELVGKEARARDAANQQLSRA 1003
Cdd:pfam12128  278 QEERQ---ETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGafLDADIETAAADQEQLPSWQS 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1004 NLLNKE-----LEDTKQDLKHSTD-----VNKQLEQDIRDLKERLANIgkggrisRDSTTGTDGGAFGDRSSVADPSRTR 1073
Cdd:pfam12128  355 ELENLEerlkaLTGKHQDVTAKYNrrrskIKEQNNRDIAGIKDKLAKI-------REARDRQLAVAEDDLQALESELREQ 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1074 GAAGSTVFVPAAEDIESRGGGE--------------IDIPSSGDVIHGRDGRDGRDAGNRGTHTITNTK---------ER 1130
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGELklrlnqatatpellLQLENFDERIERAREEQEAANAEVERLQSELRQarkrrdqasEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1131 IERIEKNILDRYHDDELVEHKI------------REVNDrWKRELERLENE----KDDL--ERRIRELEDELSQIGRGND 1192
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLfpqagtllhflrKEAPD-WEQSIGKVISPellhRTDLdpEVWDGSVGGELNLYGVKLD 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1193 KTENDITE---LKRKHAAEIDKLKSDISALHDKHlSDLDDEKEQYGKAVEN-----------LKSVEDDLRdKLNNLEKQ 1258
Cdd:pfam12128  587 LKRIDVPEwaaSEEELRERLDKAEEALQSAREKQ-AAAEEQLVQANGELEKasreetfartaLKNARLDLR-RLFDEKQS 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1259 LADSLNRenELEREKRDYDEKINSLYGQNQKIKDEW--------DDFRNDADKEIQKWK-----TDAYTVRSEAkALETT 1325
Cdd:pfam12128  665 EKDKKNK--ALAERKDSANERLNSLEAQLKQLDKKHqawleeqkEQKREARTEKQAYWQvvegaLDAQLALLKA-AIAAR 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1326 NTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANK 1405
Cdd:pfam12128  742 RSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIER 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1406 wrgeldAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLqNAFRE--KTKQAD----HLNQL 1479
Cdd:pfam12128  822 ------AISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKL-ATLKEdaNSEQAQgsigERLAQ 894

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1480 ASQFDTKLTKLRNELQD--TNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQ 1537
Cdd:pfam12128  895 LEDLKLKRDYLSESVKKyvEHFKNVIADHSGSGLAETWESLREEDHYQNDKGIRLLDYRK 954
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 685-1262 7.09e-06

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 51.28  E-value: 7.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    685 ERVAAEKARKFLEDELAKLQAsfQKSSTDDARKLRDEMDEhtnsiQEEFKTRIDELNRRvENLLRENNRLKSEVNPLKDK 764
Cdd:pfam05557   12 SQLQNEKKQMELEHKRARIEL--EKKASALKRQLDRESDR-----NQELQKRIRLLEKR-EAEAEEALREQAELNRLKKK 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    765 YRDleneynSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDD 844
Cdd:pfam05557   84 YLE------ALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQN 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    845 YQKQKDEHARHLFDIRhKLETEIKGRQDLEKNGARNNDELDKlrqtISDYESQINLLRRHNDELDTTIkGHQGKITHLEN 924
Cdd:pfam05557  158 LEKQQSSLAEAEQRIK-ELEFEIQSQEQDSEIVKNSKSELAR----IPELEKELERLREHNKHLNENI-ENKLLLKEEVE 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    925 ELHSRSGEIEKLNDLNQRLQKEKQDI---LNQKLKLDgdvQALKETIRK---LENELEKLRNENKELVGKEArardAANQ 998
Cdd:pfam05557  232 DLKRKLEREEKYREEAATLELEKEKLeqeLQSWVKLA---QDTGLNLRSpedLSRRIEQLQQREIVLKEENS----SLTS 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    999 QLSRANLLNKELED-TKQDLKHSTDVNKQLEQD---IRDLKERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTRG 1074
Cdd:pfam05557  305 SARQLEKARRELEQeLAQYLKKIEDLNKKLKRHkalVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLLERIEE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1075 AAGSTVFVPAAEDiesrgggeiDIPSSGDVIHgrdgrdgrdagnrgtHTITNTKERIERIEKNILDRYHDDELVE-HKIR 1153
Cdd:pfam05557  385 AEDMTQKMQAHNE---------EMEAQLSVAE---------------EELGGYKQQAQTLERELQALRQQESLADpSYSK 440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1154 EVNDRWKRELERLENEKDDLERRIRELEDELSQ---IGRGNDK-------TENDITELKRKHAAEIDKLKSDISALHDkH 1223
Cdd:pfam05557  441 EEVDSLRRKLETLELERQRLREQKNELEMELERrclQGDYDPKktkvlhlSMNPAAEAYQQRKNQLEKLQAEIERLKR-L 519

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 25151529   1224 LSDLDDEKEQYGKAVEnlkSVEDDLRDKLNNLEKQLADS 1262
Cdd:pfam05557  520 LKKLEDDLEQVLRLPE---TTSTMNFKEVLDLRKELESA 555
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
525-787 7.12e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.56  E-value: 7.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  525 IERNIELESrgDDSQRKIAELEAELRRNREKLNEAQGALKKlhemaqdseknvdgtvsikrtrslspgktplppsealra 604
Cdd:COG3206  162 LEQNLELRR--EEARKALEFLEEQLPELRKELEEAEAALEE--------------------------------------- 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  605 vrntFRNKdNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEA 684
Cdd:COG3206  201 ----FRQK-NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAEL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  685 ERVAAEKARKFLED--ELAKLQASFQksstddarKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEV---N 759
Cdd:COG3206  276 EAELAELSARYTPNhpDVIALRAQIA--------ALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLaelP 347

                        250       260       270
                 ....*....|....*....|....*....|...
gi 25151529  760 PLKDKYRDLENEYNSTQRRIEE-----KETQIR 787
Cdd:COG3206  348 ELEAELRRLEREVEVARELYESllqrlEEARLA 380
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1735-2221 7.89e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 7.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1735 LEGTLQSLLNKIEKLEMERN---ELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLqsaktllRS 1811
Cdd:PRK02224  211 LESELAELDEEIERYEEQREqarETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV-------RD 283

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1812 QEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDS 1891
Cdd:PRK02224  284 LRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELRE 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1892 DTNKYQLQIASFESERQILTEKIKELDGAL-----RLSDSKVQ--DMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSH 1964
Cdd:PRK02224  364 EAAELESELEEAREAVEDRREEIEELEEEIeelreRFGDAPVDlgNAEDFLEELREERDELREREAELEATLRTARERVE 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1965 EYQLLKD--------QLLNTQNELNGANNRKQQ---LENELLNVRSEVRDYKQRvHDVNNRVSELQRQLQDANTEKNRVE 2033
Cdd:PRK02224  444 EAEALLEagkcpecgQPVEGSPHVETIEEDRERveeLEAELEDLEEEVEEVEER-LERAEDLVEAEDRIERLEERREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2034 DRFLSVEKVVNTMRTTETDLRQQ---LETAKNEKRVATKEL----EDLKRRLAQLENERrnssqlsdGWKKEKITLLKKI 2106
Cdd:PRK02224  523 ELIAERRETIEEKRERAEELRERaaeLEAEAEEKREAAAEAeeeaEEAREEVAELNSKL--------AELKERIESLERI 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2107 ELLENEKRRTDAAIRETALQREAieksLNAMERENKELYKncAQLQQQIAQLEMENGNRILEL-TNKQREEQ-----ERQ 2180
Cdd:PRK02224  595 RTLLAAIADAEDEIERLREKREA----LAELNDERRERLA--EKRERKRELEAEFDEARIEEArEDKERAEEyleqvEEK 668

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 25151529  2181 LIRMRQEKGQIEKVIENRErthrNRIKQLEDqiaiLRDQLD 2221
Cdd:PRK02224  669 LDELREERDDLQAEIGAVE----NELEELEE----LRERRE 701
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1148-1280 8.00e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 8.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1148 VEHKIREVndrwKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHA-------------------AE 1208
Cdd:COG1579   22 LEHRLKEL----PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyeeqlgnvrnnkeyealqKE 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1209 IDKLKSDISALHDKHLS---DLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKI 1280
Cdd:COG1579   98 IESLKRRISDLEDEILElmeRIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1786-2220 8.23e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 8.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1786 DNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMvaaELQARGKEAQLRH----LNEQLKNLRTDLDNA 1861
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAEL---NQLLRTLDDQWKEkrdeLNGELSAADAAVAKD 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1862 HTDIRSLRDKEEQWDSSRfqLETKMRESD------SDTNKYQLQIASFESERQILTEKIKELDGALRLS-DSKVQDMKDD 1934
Cdd:pfam12128  321 RSELEALEDQHGAFLDAD--IETAAADQEqlpswqSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIKDK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1935 TDKLR--RDLTKA------ESVENELRKTIDIQSKTSHEYQLlkdQLLNTQNELNGANNRKQQLENELLNVR---SEVRD 2003
Cdd:pfam12128  399 LAKIReaRDRQLAvaeddlQALESELREQLEAGKLEFNEEEY---RLKSRLGELKLRLNQATATPELLLQLEnfdERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2004 YKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNE-KRVATKELEDLKRRLAQLE 2082
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTlLHFLRKEAPDWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2083 NER----------RNSSQLSDGWKKEKITL-LKKIELLE----NEKRRTDAAIRETALQ--REAIEKSLNAMERENKELY 2145
Cdd:pfam12128  556 SPEllhrtdldpeVWDGSVGGELNLYGVKLdLKRIDVPEwaasEEELRERLDKAEEALQsaREKQAAAEEQLVQANGELE 635

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   2146 KncaqlqqqiAQLEMENGNRILEltnKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQL 2220
Cdd:pfam12128  636 K---------ASREETFARTALK---NARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKH 698
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1988-2138 9.18e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 9.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1988 QQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEK--R 2065
Cdd:COG1579   13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKeyE 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529 2066 VATKELEDLKRRLAQLENERRN----SSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAME 2138
Cdd:COG1579   93 ALQKEIESLKRRISDLEDEILElmerIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 634-1539 9.92e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 9.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    634 LNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLqasfqksstd 713
Cdd:TIGR00606  181 ATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPL---------- 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    714 darKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSE-VNPLKDKYRDLENEYNSTQRRIEEKETQirysddi 792
Cdd:TIGR00606  251 ---KNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKmEKVFQGTDEQLNDLYHNHQRTVREKERE------- 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    793 RRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQlkeikIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQD 872
Cdd:TIGR00606  321 LVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH-----IRARDSLIQSLATRLELDGFERGPFSERQIKNF 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    873 LEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILN 952
Cdd:TIGR00606  396 HTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    953 qklkldgdvqaLKETIRKLENELEKLrNENKELVGKEARARDAANQQLSRANLLNKELEDTKQdLKHSTDVNKQLEQDIR 1032
Cdd:TIGR00606  476 -----------LDQELRKAERELSKA-EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ-LNHHTTTRTQMEMLTK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1033 DlkerlaNIGKGGRISRDSTTGTDggafgdrssvadpsRTRGAAGSTVFVPAAEDIESRGGGEIDIpssgdvihgrdgrd 1112
Cdd:TIGR00606  543 D------KMDKDEQIRKIKSRHSD--------------ELTSLLGYFPNKKQLEDWLHSKSKEINQ-------------- 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1113 grdagnrgthtitnTKERIERIEKNIldryhddelveHKIREVNDRWKRELERLENEKDDLERRIREL---EDELSQIGR 1189
Cdd:TIGR00606  589 --------------TRDRLAKLNKEL-----------ASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLER 643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1190 GNDKTENDITELKRKHAAeidklksdiSALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENEL 1269
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGA---------TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKST 714

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1270 ERE----KRDYDEKINSLYGQN---QKIKDEWDDFRN---DADKEIQKWKTDaytVRSEAKALETTNTALKAQ--LQAAN 1337
Cdd:TIGR00606  715 ESElkkkEKRRDEMLGLAPGRQsiiDLKEKEIPELRNklqKVNRDIQRLKND---IEEQETLLGTIMPEEESAkvCLTDV 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1338 DRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMD---------LESTQNRLRSLEDQHSTLQSDANKWRG 1408
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQheldtvvskIELNRKLIQDQQEQIQHLKSKTNELKS 871

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1409 E---LDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQA-DHLNQLASQFD 1484
Cdd:TIGR00606  872 EklqIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAqDKVNDIKEKVK 951

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   1485 TK---LTKLRNELQD-TNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTT 1539
Cdd:TIGR00606  952 NIhgyMKDIENKIQDgKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1437-1613 1.01e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1437 RLKSAEDALKELKNSLSH--AKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSDTER-NALRN 1513
Cdd:COG4913  266 AARERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLER 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1514 ELQKLSQELkfgnEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNALQELEARKyeiNDLTSRLDSTEQRLATLQQDYIKAD 1593
Cdd:COG4913  346 EIERLEREL----EERERRRARLEALLAALGLPLPASAEEFAALRAEAAALL---EALEEELEALEEALAEAEAALRDLR 418

                        170       180
                 ....*....|....*....|
gi 25151529 1594 SERDILSDALRRFQSSANRV 1613
Cdd:COG4913  419 RELRELEAEIASLERRKSNI 438
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1839-2217 1.05e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1839 GKEAQLRHLNEQLKNLRTDLDNAHtdIRSLRDKEEQ----WDSSRFQLETKMRESDSDTNKYQLQiasfESERQILTEKI 1914
Cdd:pfam02463  113 GKNVTKKEVAELLESQGISPEAYN--FLVQGGKIEIiammKPERRLEIEEEAAGSRLKRKKKEAL----KKLIEETENLA 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1915 KELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENEL 1994
Cdd:pfam02463  187 ELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEK 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1995 LnvrsevrDYKQRVHDVNNRVSELQrqlqdaNTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDL 2074
Cdd:pfam02463  267 L-------AQVLKENKEEEKEKKLQ------EEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2075 KRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQ 2154
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL 413

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529   2155 IAQLEMENGNRILELTNKQREEQERQLIrmRQEKGQIEKVIENRERTHRNRIKQLEDQIAILR 2217
Cdd:pfam02463  414 ARQLEDLLKEEKKEELEILEEEEESIEL--KQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
PRK01156 PRK01156
chromosome segregation protein; Provisional
 718-1274 1.07e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.06  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   718 LRDEMDEHTNSIqEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKEtqiRYSDDIRRnIQ 797
Cdd:PRK01156  188 LEEKLKSSNLEL-ENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKN---RYESEIKT-AE 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   798 KDLDDLREKYDRVHTDNE---KILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLE 874
Cdd:PRK01156  263 SDLSMELEKNNYYKELEErhmKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYI 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   875 KNGARNnDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELhSRSGEIEKLNDlnQRLQKEKQDILNQK 954
Cdd:PRK01156  343 KKKSRY-DDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFI-SEILKIQEIDP--DAIKKELNEINVKL 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   955 LKLDGDVQALKETIRKLENELEKLRNENKELVGK-----------EARARDAANQQLSRANLLNKELEDTKQDLKhstdv 1023
Cdd:PRK01156  419 QDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgttlgEEKSNHIINHYNEKKSRLEEKIREIEIEVK----- 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1024 nkQLEQDIRDLKERLANIgKGGRISR--------DSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGE 1095
Cdd:PRK01156  494 --DIDEKIVDLKKRKEYL-ESEEINKsineynkiESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSW 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1096 IDIPSSGDVIhgrdgrdgrdagnrgthTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLER 1175
Cdd:PRK01156  571 LNALAVISLI-----------------DIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNN 633

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1176 RIRELEDELSQIGRGNDKTENditelKRKHAAEIDKLKSDISALHDKhLSDLDDEKEQYGKAVEN-------LKSVEDDL 1248
Cdd:PRK01156  634 KYNEIQENKILIEKLRGKIDN-----YKKQIAEIDSIIPDLKEITSR-INDIEDNLKKSRKALDDakanrarLESTIEIL 707

                         570       580
                  ....*....|....*....|....*.
gi 25151529  1249 RDKLNNLEKQLADslnRENELEREKR 1274
Cdd:PRK01156  708 RTRINELSDRIND---INETLESMKK 730
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1731-2105 1.23e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKT-------TETHTTINQKETRYRNIEDNLQDAEEERRALESRLQ 1803
Cdd:TIGR04523  315 ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQIN 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1804 SAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLR---TDLDNAHTDIRSLRDKEEQ------ 1874
Cdd:TIGR04523  395 DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETqlkvls 474

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1875 ---------WDSSRFQLETKMRESDSDTNKYQL---QIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDL 1942
Cdd:TIGR04523  475 rsinkikqnLEQKQKELKSKEKELKKLNEEKKEleeKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL 554

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1943 TKaesveNELRKTIDIQSKTSHEYQLLKDQLLNTQNELngaNNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQL 2022
Cdd:TIGR04523  555 KK-----ENLEKEIDEKNKEIEELKQTQKSLKKKQEEK---QELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2023 QDANTEKNRVEDRFLSVEKVVNTMRTTetdlrqqLETAKNEKRVATKELEDLKRRLAQLenerrnsSQLSDGWKKEKITL 2102
Cdd:TIGR04523  627 EKLSSIIKNIKSKKNKLKQEVKQIKET-------IKEIRNKWPEIIKKIKESKTKIDDI-------IELMKDWLKELSLH 692


                   ...
gi 25151529   2103 LKK 2105
Cdd:TIGR04523  693 YKK 695
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1729-2056 1.39e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1729 GFD----IANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTEThttinQKETRYRNIEDNLQDAEEERRALE---SR 1801
Cdd:COG4913  605 GFDnrakLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEIDVASAEREIAELEaelER 679

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1802 LQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRdkeeqwdssRFQ 1881
Cdd:COG4913  680 LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL---------RAL 750

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1882 LETKMRESDSDTNKYQLQiASFESERQILTEKIKELDGALRLSDSK-VQDMKDDTDKLRRDLTKAESVENELRK--TIDI 1958
Cdd:COG4913  751 LEERFAAALGDAVERELR-ENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPEYLALLDRleEDGL 829

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1959 QSKTSHEYQLLKDQ----LLNTQNELNGANNR-KQQLE--NELL-----------------NVRSEVRDYKQRVHDVNNR 2014
Cdd:COG4913  830 PEYEERFKELLNENsiefVADLLSKLRRAIREiKERIDplNDSLkripfgpgrylrlearpRPDPEVREFRQELRAVTSG 909

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 25151529 2015 VSELQRQLQdanteknrvEDRFLSVEKVVNTMRTTETDLRQQ 2056
Cdd:COG4913  910 ASLFDEELS---------EARFAALKRLIERLRSEEEESDRR 942
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1731-2221 1.49e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1731 DIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIED---NLQDAEEERRALESRLQSAKT 1807
Cdd:PRK01156  184 NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSalnELSSLEDMKNRYESEIKTAES 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1808 LLRSQEEALKQRDE-ERRQMK---SKMVAAELQARG---KEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDssrf 1880
Cdd:PRK01156  264 DLSMELEKNNYYKElEERHMKiinDPVYKNRNYINDyfkYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYN---- 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1881 QLETKMRESDsDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDK-LRRDLTKAESVENEL----RKT 1955
Cdd:PRK01156  340 DYIKKKSRYD-DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEiLKIQEIDPDAIKKELneinVKL 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1956 IDIQSKTSHEYQLL------KDQLLNTQNELNGANNRK---QQLENEllNVRSEVRDYKQRVHDVNNRVSELQRQLQDAN 2026
Cdd:PRK01156  419 QDISSKVSSLNQRIralrenLDELSRNMEMLNGQSVCPvcgTTLGEE--KSNHIINHYNEKKSRLEEKIREIEIEVKDID 496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2027 TEKNRVEDR--FLSVEKVvntmrttetdlrQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLL- 2103
Cdd:PRK01156  497 EKIVDLKKRkeYLESEEI------------NKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLd 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2104 -KKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQ--QQIAQLEMENGNRILELTNKQREEQERQ 2180
Cdd:PRK01156  565 sKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyIDKSIREIENEANNLNNKYNEIQENKIL 644

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 25151529  2181 LIRMRQE----KGQIEKV--IENRERTHRNRIKQLEDQIAILRDQLD 2221
Cdd:PRK01156  645 IEKLRGKidnyKKQIAEIdsIIPDLKEITSRINDIEDNLKKSRKALD 691
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1128-1523 1.53e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 1.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1128 KERIerieKNILDR--YHDDELVEHKIREVNDRWKRELERLE--------NEKDDLERRIREledELSQIGRGN-DKTEN 1196
Cdd:TIGR01612  606 KEKI----KNISDKneYIKKAIDLKKIIENNNAYIDELAKISpyqvpehlKNKDKIYSTIKS---ELSKIYEDDiDALYN 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1197 DITELKRKHA-------AEIDKLKSDISALHDK-----------HLSDLDDEKEQYGKA-VENLKSVEDDLRDKLNnleK 1257
Cdd:TIGR01612  679 ELSSIVKENAidntedkAKLDDLKSKIDKEYDKiqnmetatvelHLSNIENKKNELLDIiVEIKKHIHGEINKDLN---K 755

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1258 QLADSLNRENELErekrdydEKINslygqnqkikdewdDFRNDADkEIQKWKTDAYTVRSEAKALETTNTALKAQLQAAN 1337
Cdd:TIGR01612  756 ILEDFKNKEKELS-------NKIN--------------DYAKEKD-ELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNY 813

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1338 DRIDHLTKTVNDHTSKVRDLTSQVRHLEDELAdtkgNLVQKEMDLEStqNRLRSLEDQHSTLQSDANKWRGELdaalrEN 1417
Cdd:TIGR01612  814 DKSKEYIKTISIKEDEIFKIINEMKFMKDDFL----NKVDKFINFEN--NCKEKIDSEHEQFAELTNKIKAEI-----SD 882

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1418 DILKSNNTNMETDLTRLKNRLKSAE------DALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQ------------- 1478
Cdd:TIGR01612  883 DKLNDYEKKFNDSKSLINEINKSIEeeyqniNTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnidtikesnliek 962

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 25151529   1479 -LASQFDTKLTKLRNELQDTNDKLITSDTERNalRNELQKLSQELK 1523
Cdd:TIGR01612  963 sYKDKFDNTLIDKINELDKAFKDASLNDYEAK--NNELIKYFNDLK 1006
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1883-2101 1.65e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.83  E-value: 1.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1883 ETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTID----I 1958
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGerarA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1959 QSKTSHEYQLLkDQLLNTQNeLNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLS 2038
Cdd:COG3883   95 LYRSGGSVSYL-DVLLGSES-FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2039 VEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKIT 2101
Cdd:COG3883  173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1129-1322 1.97e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.93  E-value: 1.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1129 ERIERIEKN------ILDRYHDDELVEHKIREVN-----DRWKRELERLENEKDDLERRIRELEDELSQIgrgndktEND 1197
Cdd:PRK05771   43 ERLRKLRSLltklseALDKLRSYLPKLNPLREEKkkvsvKSLEELIKDVEEELEKIEKEIKELEEEISEL-------ENE 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1198 ITELKrKHAAEIDKLKS---DISALHDKHLSDL--------DDEKEQYGKAVENLKSVEDD----------LRDKLNNLE 1256
Cdd:PRK05771  116 IKELE-QEIERLEPWGNfdlDLSLLLGFKYVSVfvgtvpedKLEELKLESDVENVEYISTDkgyvyvvvvvLKELSDEVE 194

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529  1257 KQLADSLNRENELEREK------RDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKAL 1322
Cdd:PRK05771  195 EELKKLGFERLELEEEGtpseliREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEAL 266
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1904-2221 2.28e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1904 ESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTI-DIQSKTSHEYQLLKD---QLLNTQNE 1979
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIkDLNDKLKKNKDKINKlnsDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1980 LNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLET 2059
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2060 AKNEKRVATKELEDLKrrlAQLENERRNSSQLSDgWKKEKITLLKKIELLENEKRRTDAAIRETALQreaIEKSLNAMER 2139
Cdd:TIGR04523  192 IKNKLLKLELLLSNLK---KKIQKNKSLESQISE-LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ---LNQLKDEQNK 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2140 ENKELYKNcaqlqqqiaQLEMENGNRILELTNKQREEQERQLIRMRQEK---------GQIEKV------IENRERTHRN 2204
Cdd:TIGR04523  265 IKKQLSEK---------QKELEQNNKKIKELEKQLNQLKSEISDLNNQKeqdwnkelkSELKNQekkleeIQNQISQNNK 335

                          330
                   ....*....|....*..
gi 25151529   2205 RIKQLEDQIAILRDQLD 2221
Cdd:TIGR04523  336 IISQLNEQISQLKKELT 352
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1835-2094 2.34e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1835 LQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEqwdssrfqletkmresdsdtnKYQLQIASFESERQILTEKI 1914
Cdd:COG4942   13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEK---------------------ALLKQLAALERRIAALARRI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1915 KELDGALRLSDSKVQDMKDDTDKLRRDLtkaESVENELRKTIDIQSKTSHEYQLlkdQLLNTQNELNGANNRKQQLENEL 1994
Cdd:COG4942   72 RALEQELAALEAELAELEKEIAELRAEL---EAQKEELAELLRALYRLGRQPPL---ALLLSPEDFLDAVRRLQYLKYLA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1995 LNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDL 2074
Cdd:COG4942  146 PARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225

                        250       260
                 ....*....|....*....|
gi 25151529 2075 KRRLAQLENERRNSSQLSDG 2094
Cdd:COG4942  226 EALIARLEAEAAAAAERTPA 245
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 831-1125 2.42e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.06  E-value: 2.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  831 AEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRrhnDELDT 910
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR---EELGE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  911 TIKGHQ---GKITHLENELHSRS-----GEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNEN 982
Cdd:COG3883   91 RARALYrsgGSVSYLDVLLGSESfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  983 KELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGAFGD 1062
Cdd:COG3883  171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAG 250

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 1063 RSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGTHTIT 1125
Cdd:COG3883  251 AAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASGGSGGGSGGAGGV 313
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
740-1008 2.44e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 2.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  740 LNRRVENLLRENNRLKSEvnPLKDKYRDLENEYNSTQRRIEEKETQIRysddirrniqkdldDLREKYDRVHTDNEkilg 819
Cdd:COG3206  154 ANALAEAYLEQNLELRRE--EARKALEFLEEQLPELRKELEEAEAALE--------------EFRQKNGLVDLSEE---- 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  820 elehaqkaAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLekngaRNNDELDKLRQTISDYESQIN 899
Cdd:COG3206  214 --------AKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELA 280

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  900 LLRRHNDELDTTIKGHQgkithlenelhsrsgeiEKLNDLNQRLQKEKQDILNQklkLDGDVQALKETIRKLENELEKLR 979
Cdd:COG3206  281 ELSARYTPNHPDVIALR-----------------AQIAALRAQLQQEAQRILAS---LEAELEALQAREASLQAQLAQLE 340

                        250       260       270
                 ....*....|....*....|....*....|...
gi 25151529  980 NENKELVGKEARA----RDAANQQLSRANLLNK 1008
Cdd:COG3206  341 ARLAELPELEAELrrleREVEVARELYESLLQR 373
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1821-2201 2.76e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 49.69  E-value: 2.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1821 EERRQMKSKMVAAELQA--RGKEAQLRhLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQL 1898
Cdd:COG5022  737 EDMRDAKLDNIATRIQRaiRGRYLRRR-YLQALKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSY 815

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1899 QIASFESERQILTEKIkeldgaLRLSDSKVQDMKDDTDKLR--RDLTKAESVENELRKTIDIQSKTshEYQLLKDQLLNT 1976
Cdd:COG5022  816 LACIIKLQKTIKREKK------LRETEEVEFSLKAEVLIQKfgRSLKAKKRFSLLKKETIYLQSAQ--RVELAERQLQEL 887

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1977 QNELNGANNRKQ---QLENELLNVRSEVRdykqrvhdvNNRVSELQRQLQDANTEKNRVEDRFLSVEKvvnTMRTTETDL 2053
Cdd:COG5022  888 KIDVKSISSLKLvnlELESEIIELKKSLS---------SDLIENLEFKTELIARLKKLLNNIDLEEGP---SIEYVKLPE 955

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2054 RQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKrrtdaairetalqreaieKS 2133
Cdd:COG5022  956 LNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQEST------------------KQ 1017

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529 2134 LNAMERENKELYKN----CAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERT 2201
Cdd:COG5022 1018 LKELPVEVAELQSAskiiSSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLEST 1089
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1789-2212 3.06e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 3.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1789 QDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARgKEAQLRHLNEQLKNLRTDLdNAHTDIRSL 1868
Cdd:TIGR00618  208 LCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLK-KQQLLKQLRARIEELRAQE-AVLEETQER 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1869 RDKEEQW----------DSSRFQ-------LETKMRESDSDTNKYQL---QIASFESERQILTEKIKELDgALRLSDSKV 1928
Cdd:TIGR00618  286 INRARKAaplaahikavTQIEQQaqrihteLQSKMRSRAKLLMKRAAhvkQQSSIEEQRRLLQTLHSQEI-HIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1929 QDMKDDTDK----------LRRDLTKAESVENELRKTIDIQSKTSH-------EYQLLKDQLLNTQNELNGANNRKQQLE 1991
Cdd:TIGR00618  365 TSIREISCQqhtltqhihtLQQQKTTLTQKLQSLCKELDILQREQAtidtrtsAFRDLQGQLAHAKKQQELQQRYAELCA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1992 NELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQlETAKNEKRVATKEL 2071
Cdd:TIGR00618  445 AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS-CIHPNPARQDIDNP 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2072 EDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQL 2151
Cdd:TIGR00618  524 GPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL 603

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2152 QQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEK---------VIENRERTHRNRIKQLEDQ 2212
Cdd:TIGR00618  604 SEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLtalhalqltLTQERVREHALSIRVLPKE 673
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 778-936 3.16e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 3.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  778 RIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEH--ARH 855
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  856 LFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRrhnDELDTTIKGHQGKITHLENELHSRSGEIEK 935
Cdd:COG1579   91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELE---AELEEKKAELDEELAELEAELEELEAEREE 167


                 .
gi 25151529  936 L 936
Cdd:COG1579  168 L 168
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 613-768 3.55e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 3.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  613 DNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKL---------RASE 683
Cdd:COG1579   16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnkeyEALQ 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  684 AERVAAEKARKFLEDELAKL--QASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNP- 760
Cdd:COG1579   96 KEIESLKRRISDLEDEILELmeRIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPe 175


                 ....*...
gi 25151529  761 LKDKYRDL 768
Cdd:COG1579  176 LLALYERI 183
46 PHA02562
endonuclease subunit; Provisional
 1779-2029 3.69e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 48.86  E-value: 3.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1779 TRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAaelQARGKEAQLRHLNEQLKNLRTDL 1858
Cdd:PHA02562  174 DKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVE---EAKTIKAEIEELTDELLNLVMDI 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1859 DNAHTDIRSLRDKEEQWDS--SRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQdmkddtd 1936
Cdd:PHA02562  251 EDPSAALNKLNTAAAKIKSkiEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAID------- 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1937 klrrdltKAESVENELRKtidiQSKTSHEyqlLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVS 2016
Cdd:PHA02562  324 -------ELEEIMDEFNE----QSKKLLE---LKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELD 389

                         250
                  ....*....|...
gi 25151529  2017 ELQRQLQDANTEK 2029
Cdd:PHA02562  390 KIVKTKSELVKEK 402
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 350-1017 4.33e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 49.05  E-value: 4.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    350 LSLEDENDRLRREFEryANDSK-----DKEKTFINRERNLAQYLSDEQRKMLDLWTELQRVRKQFSDLKTHTEEDLDKQK 424
Cdd:pfam10174    6 RDLQRENELLRRELD--IKESKlgssmNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDEL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    425 aeftRAIRNVNNISrNAAFSAGAGDGLGLYGLEDGGDVN--RTTNNYEKVFIE------TIKRM-------NGTGGAGSA 489
Cdd:pfam10174   84 ----RAQRDLNQLL-QQDFTTSPVDGEDKFSTPELTEENfrRLQSEHERQAKElfllrkTLEEMelrietqKQTLGARDE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    490 SSADLLEELrkiRGGGSSEGDAELHKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQG--ALKKLH 567
Cdd:pfam10174  159 SIKKLLEML---QSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKtkALQTVI 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    568 EMA-------QDSEKNVDGTVSIKRTRSLSPGKTPLPPSEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENa 640
Cdd:pfam10174  236 EMKdtkisslERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLET- 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    641 dearrrLDKQFADAKREISNLQKSVDEAERnsrrtddklRAS------EAERVAAEKARKFLEDELAKLQASFQKSSTDD 714
Cdd:pfam10174  315 ------LTNQNSDCKQHIEVLKESLTAKEQ---------RAAilqtevDALRLRLEEKESFLNKKTKQLQDLTEEKSTLA 379

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    715 A--RKLRDEMDehtnsIQEEfktRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNST--------------QRR 778
Cdd:pfam10174  380 GeiRDLKDMLD-----VKER---KINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTdtalttleealsekERI 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    779 IEEKETQIRYSDDIRR----NIQKDLDDLREKYDRVHTD-NEKILGELEHAQKAAHLAEQQLKeikiqRDDYQKQKDEHA 853
Cdd:pfam10174  452 IERLKEQREREDRERLeeleSLKKENKDLKEKVSALQPElTEKESSLIDLKEHASSLASSGLK-----KDSKLKSLEIAV 526

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    854 RHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQtisdYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEI 933
Cdd:pfam10174  527 EQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRL----LEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKI 602

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    934 EKLNDLNQRLQKEkQDILNQKLKldgDVQALKEtiRKLENELEKLRNEnkelvgKEARARDAANQQLSRanlLNKELEDT 1013
Cdd:pfam10174  603 AELESLTLRQMKE-QNKKVANIK---HGQQEMK--KKGAQLLEEARRR------EDNLADNSQQLQLEE---LMGALEKT 667


                   ....
gi 25151529   1014 KQDL 1017
Cdd:pfam10174  668 RQEL 671
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1795-2221 4.57e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 4.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1795 RRALESRLQ-SAKTLLRSQEEALKQRDEERRQMKSKMVAAELQA---RGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRD 1870
Cdd:COG4717   44 RAMLLERLEkEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEK 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1871 KEEQWDssrfqLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRlsdsKVQDMKDDTDKLRRDLTkaESVEN 1950
Cdd:COG4717  124 LLQLLP-----LYQELEALEAELAELPERLEELEERLEELRELEEELEELEA----ELAELQEELEELLEQLS--LATEE 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1951 ELRKTIDiqsktshEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRvhdvnNRVSELQRQLQDANT--- 2027
Cdd:COG4717  193 ELQDLAE-------ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-----ERLKEARLLLLIAAAlla 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2028 -----------------------------------EKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELE 2072
Cdd:COG4717  261 llglggsllsliltiagvlflvlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2073 DLKRRLAQLENERRNSSQLSDGWKKEKItLLKKIELLENEKRRTDAAIRETALQ---REAIEKSLNAMERENKELYKNCA 2149
Cdd:COG4717  341 ELLDRIEELQELLREAEELEEELQLEEL-EQEIAALLAEAGVEDEEELRAALEQaeeYQELKEELEELEEQLEELLGELE 419

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529 2150 QLQQQIAQLEMEngNRILELtNKQREEQERQLIRMRQEKGQIEKVIENRERthRNRIKQLEDQIAILRDQLD 2221
Cdd:COG4717  420 ELLEALDEEELE--EELEEL-EEELEELEEELEELREELAELEAELEQLEE--DGELAELLQELEELKAELR 486
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 646-810 4.59e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.23  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  646 RLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQASFQK--------SSTDDARK 717
Cdd:COG1579   14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKyeeqlgnvRNNKEYEA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  718 LRDEMDEHTNSIqEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRysdDIRRNIQ 797
Cdd:COG1579   94 LQKEIESLKRRI-SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE---AEREELA 169

                        170
                 ....*....|....
gi 25151529  798 KDLD-DLREKYDRV 810
Cdd:COG1579  170 AKIPpELLALYERI 183
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1427-2115 5.29e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 5.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1427 METDLTRLknrlksaEDALKELKNSLSHAKTEKER------LQNAFREKTKQAdHLNQLAsQFDTKLTKLRNELQDTNDK 1500
Cdd:COG1196  184 TEENLERL-------EDILGELERQLEPLERQAEKaeryreLKEELKELEAEL-LLLKLR-ELEAELEELEAELEELEAE 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1501 LITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQ---TTIDDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDS 1577
Cdd:COG1196  255 LEELEAELAELEAELEELRLELEELELELEEAQAEEYellAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1578 TEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINfhtfvdggagyvdgvpggtsvigggpsaqrsgaydpSSGGVI 1657
Cdd:COG1196  335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA------------------------------------ELAEAE 378

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1658 GSGISGGPGGSDFGREIEIGRGDsdqsdvayprsvpfppsadfssgrpgAASAGGRVINNLDgtttvnmnggfDIANLEG 1737
Cdd:COG1196  379 EELEELAEELLEALRAAAELAAQ--------------------------LEELEEAEEALLE-----------RLERLEE 421

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1738 TLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALK 1817
Cdd:COG1196  422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1818 QRDEERRQMKSKMVAAELQARGKE-------------AQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLET 1884
Cdd:COG1196  502 DYEGFLEGVKAALLLAGLRGLAGAvavligveaayeaALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDK 581

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1885 KMRESDSDTNKYQLQI----ASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQS 1960
Cdd:COG1196  582 IRARAALAAALARGAIgaavDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1961 KTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVE 2040
Cdd:COG1196  662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2041 kvvntMRTTETDLRQQLETAKNEKRVAT--KELEDLKRRLAQLE-------------NERRN--SSQLSDGwKKEKITLL 2103
Cdd:COG1196  742 -----LEEEELLEEEALEELPEPPDLEEleRELERLEREIEALGpvnllaieeyeelEERYDflSEQREDL-EEARETLE 815

                        730
                 ....*....|..
gi 25151529 2104 KKIELLENEKRR 2115
Cdd:COG1196  816 EAIEEIDRETRE 827
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1329-1587 5.49e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 5.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1329 LKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELadtkgNLVQKEMD-LESTQNRLRSLEDQHSTLQSDANKWR 1407
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEY-----NNAMDDYNnLKSALNELSSLEDMKNRYESEIKTAE 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1408 GELDAALRENdilksnntnmetdltrlkNRLKSAEDALKELKNSLSHAKteKERLQNAFREKtKQADHLNQLASQFDTKL 1487
Cdd:PRK01156  263 SDLSMELEKN------------------NYYKELEERHMKIINDPVYKN--RNYINDYFKYK-NDIENKKQILSNIDAEI 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1488 TKLRN------ELQDTNDKLITSDTERNALRNELQKLSQ-ELKFGN-----EQIQRKSDEYQTTIDDLAhshrvSEDSRL 1555
Cdd:PRK01156  322 NKYHAiikklsVLQKDYNDYIKKKSRYDDLNNQILELEGyEMDYNSylksiESLKKKIEEYSKNIERMS-----AFISEI 396

                         250       260       270
                  ....*....|....*....|....*....|....
gi 25151529  1556 NALQEL--EARKYEINDLTSRLDSTEQRLATLQQ 1587
Cdd:PRK01156  397 LKIQEIdpDAIKKELNEINVKLQDISSKVSSLNQ 430
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 610-854 7.35e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 7.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  610 RNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLraseAERVAA 689
Cdd:COG3883   19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL----GERARA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  690 EKARKFLEDELAKLQASfqKSSTDDARKLrdemdehtnsiqeefkTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLE 769
Cdd:COG3883   95 LYRSGGSVSYLDVLLGS--ESFSDFLDRL----------------SALSKIADADADLLEELKADKAELEAKKAELEAKL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  770 NEYNSTQRRIEEKETQIrysDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQK 849
Cdd:COG3883  157 AELEALKAELEAAKAEL---EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233


                 ....*
gi 25151529  850 DEHAR 854
Cdd:COG3883  234 AAAAA 238
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 515-706 8.37e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 8.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  515 KELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSlspgkt 594
Cdd:COG3883   40 DALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDVLLGSES------ 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  595 plpPSEALR--AVRNTFRNKDND-IQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERN 671
Cdd:COG3883  114 ---FSDFLDrlSALSKIADADADlLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE 190

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 25151529  672 SRRTDDKLRASEAERVAAEKARKFLEDELAKLQAS 706
Cdd:COG3883  191 EAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1162-1338 9.87e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 9.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1162 ELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHA---AEIDKLKSDISALHDK---------------- 1222
Cdd:COG3883   24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDklqAEIAEAEAEIEERREElgeraralyrsggsvs 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1223 ----------------HLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQ 1286
Cdd:COG3883  104 yldvllgsesfsdfldRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 25151529 1287 NQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAAND 1338
Cdd:COG3883  184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
600-896 1.00e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 1.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  600 EALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKL 679
Cdd:COG4372   66 EELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEI 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  680 RASEAERVAAEKARKFLEDELAKLQASFQKSSTDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVN 759
Cdd:COG4372  146 AEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKD 225

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  760 PLKDKYRDLENEYNSTQRRIEEKETQIrySDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIK 839
Cdd:COG4372  226 SLEAKLGLALSALLDALELEEDKEELL--EEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLN 303

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529  840 IQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYES 896
Cdd:COG4372  304 LAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLS 360
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1409-1869 1.03e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1409 ELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDT--K 1486
Cdd:COG4717   54 EADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqE 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1487 LTKLRNELQDTN---DKLITSDTERNALRNELQKLSQELkfgnEQIQRKSDEYQttiddlahshrvsEDSRLNALQELEA 1563
Cdd:COG4717  134 LEALEAELAELPerlEELEERLEELRELEEELEELEAEL----AELQEELEELL-------------EQLSLATEEELQD 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1564 RKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQ-----SSANRVINFHTFVDGGAGYVDGVPGGTSVIG 1638
Cdd:COG4717  197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSLLSLILTIA 276

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1639 GGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADFSSGRPGAASAGGRVINNL 1718
Cdd:COG4717  277 GVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1719 DGtttvnMNGGFDIANLEGTLQSLLNKIeKLEMErNELRDTLARmkkkttetHTTINQKETRYRNIEDNLQDAEEERRAL 1798
Cdd:COG4717  357 EE-----LEEELQLEELEQEIAALLAEA-GVEDE-EELRAALEQ--------AEEYQELKEELEELEEQLEELLGELEEL 421

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1799 ESRLQ--SAKTLLRSQEEALKQRDEERRQMKSKM--VAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLR 1869
Cdd:COG4717  422 LEALDeeELEEELEELEEELEELEEELEELREELaeLEAELEQLEEDGELAELLQELEELKAELRELAEEWAALK 496
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1376-1738 1.05e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1376 VQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLsha 1455
Cdd:COG3883   12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL--- 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1456 kteKERLQNAFREKTkQADHLNQL--ASQFDTKLTKL--RNELQDTNDKLItsdternalrNELQKLSQELKFGNEQIQR 1531
Cdd:COG3883   89 ---GERARALYRSGG-SVSYLDVLlgSESFSDFLDRLsaLSKIADADADLL----------EELKADKAELEAKKAELEA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1532 KSDEYQTTIDDLAhshrvsedsrlNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSAN 1611
Cdd:COG3883  155 KLAELEALKAELE-----------AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1612 RVINFHTFVDGGAGYVDGVPGGTSVIGGGPSAQRSGAYD-PSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPR 1690
Cdd:COG3883  224 AAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAgAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASGGS 303

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 25151529 1691 SVPFPPSADFSSGRPGAASAGGRVINNLDGTTTVNMNGGFDIANLEGT 1738
Cdd:COG3883  304 GGGSGGAGGVGSGGGAGAVVGGASAGGGGGSGGGGGSSGGGSGGGGGG 351
46 PHA02562
endonuclease subunit; Provisional
 1261-1472 1.08e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1261 DSLNRE--NELEREKRDYDEKINSLygqNQKIKDEwDDFRNDADKeiqkwKTDAYTVRSEAKALETTNTA--LKAQLQAA 1336
Cdd:PHA02562  169 DKLNKDkiRELNQQIQTLDMKIDHI---QQQIKTY-NKNIEEQRK-----KNGENIARKQNKYDELVEEAktIKAEIEEL 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1337 NDRIDHLTKTVNDHTSKVRDLTsqvrhleDELADTKGNL--VQKEM--------------DLESTQNRLRSLEDQHSTLQ 1400
Cdd:PHA02562  240 TDELLNLVMDIEDPSAALNKLN-------TAAAKIKSKIeqFQKVIkmyekggvcptctqQISEGPDRITKIKDKLKELQ 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1401 ---SDANKWRGELdaALRENDI---------LKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFRE 1468
Cdd:PHA02562  313 hslEKLDTAIDEL--EEIMDEFneqskklleLKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390


                  ....
gi 25151529  1469 KTKQ 1472
Cdd:PHA02562  391 IVKT 394
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
794-1041 1.10e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 46.83  E-value: 1.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  794 RNIQKDLDDLREKYDRVHTDNEKILGELEHAQKaahlaeqQLKEIKIQRDDYQKQKDEharhlfdIRHKLETEIKGRQDL 873
Cdd:COG1340    4 DELSSSLEELEEKIEELREEIEELKEKRDELNE-------ELKELAEKRDELNAQVKE-------LREEAQELREKRDEL 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  874 EKNGARNNDELDKLRQTISDYESQINLLRRHNDELDT---TIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQ--KEKQ 948
Cdd:COG1340   70 NEKVKELKEERDELNEKLNELREELDELRKELAELNKaggSIDKLRKEIERLEWRQQTEVLSPEEEKELVEKIKelEKEL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  949 DILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLE 1028
Cdd:COG1340  150 EKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELH 229

                        250
                 ....*....|...
gi 25151529 1029 QDIRDLKERLANI 1041
Cdd:COG1340  230 EEIIELQKELREL 242
PTZ00121 PTZ00121
MAEBL; Provisional
 523-1323 1.17e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   523 ESIERNIELESRgDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSE-KNVDGTVSIKRTRSLSPGKTPLPPSEA 601
Cdd:PTZ00121 1082 DAKEDNRADEAT-EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   602 LRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKfenADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRA 681
Cdd:PTZ00121 1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEELRK---AEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   682 SEAERVAAEKAR------KFLEDELAKLQASFQKSSTDDARKLR-----DEMDEHTNSIQEEFKTRIDELNRRVENllre 750
Cdd:PTZ00121 1238 DAEEAKKAEEERnneeirKFEEARMAHFARRQAAIKAEEARKADelkkaEEKKKADEAKKAEEKKKADEAKKKAEE---- 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   751 nnrlKSEVNPLKDKYRDLENEYNSTQRRIEEKetqirysddirrniqKDLDDLREKydrvhtDNEKILGELEHAQKAAHL 830
Cdd:PTZ00121 1314 ----AKKADEAKKKAEEAKKKADAAKKKAEEA---------------KKAAEAAKA------EAEAAADEAEAAEEKAEA 1368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   831 AEQQLKEIKiQRDDYQKQKDEHARHLFDIRHKLEtEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDT 910
Cdd:PTZ00121 1369 AEKKKEEAK-KKADAAKKKAEEKKKADEAKKKAE-EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   911 TIKGHQGKITHLENELHSRSGEIEKLNDLNQRL-QKEKQDILNQK---LKLDGDVQALKETIRKLENELEKLRNENKELV 986
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeEAKKADEAKKKaeeAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   987 GKEARARDAAN-----QQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDiRDLKERLANIGKggRISRDSTTGTDGGAFG 1061
Cdd:PTZ00121 1527 AKKAEEAKKADeakkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-KNMALRKAEEAK--KAEEARIEEVMKLYEE 1603

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1062 DRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVihgRDGRDGRDAGNRGTHTITNTKERIERiEKNILDR 1141
Cdd:PTZ00121 1604 EKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK---KKAEELKKAEEENKIKAAEEAKKAEE-DKKKAEE 1679

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1142 YHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEdelsQIGRGNDKTENDITELKRKhaAEIDKLKSDisalhd 1221
Cdd:PTZ00121 1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE----ELKKAEEENKIKAEEAKKE--AEEDKKKAE------ 1747

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1222 khlsDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENE---LEREKRDYDEKINSLYGQ--NQKIKDEWDD 1296
Cdd:PTZ00121 1748 ----EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEkrrMEVDKKIKDIFDNFANIIegGKEGNLVIND 1823

                         810       820
                  ....*....|....*....|....*..
gi 25151529  1297 FRNDADKEIQKWKTDAYTVRSEAKALE 1323
Cdd:PTZ00121 1824 SKEMEDSAIKEVADSKNMQLEEADAFE 1850
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 615-1038 1.24e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    615 DIQQLERKLKIAES---QVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEK 691
Cdd:TIGR00618  387 QKTTLTQKLQSLCKeldILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    692 ARKFLEDELAKLQASFQKSStdDARKLRDEMDEHTNSIQEEFKTRIDELN-------------RRVENLLRENNRLKSEv 758
Cdd:TIGR00618  467 SLKEREQQLQTKEQIHLQET--RKKAVVLARLLELQEEPCPLCGSCIHPNparqdidnpgpltRRMQRGEQTYAQLETS- 543

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    759 npLKDKYRDLENEYNSTQRrIEEKETQIRYSDDI----RRNIQKDLDDLREKYDRVHTDNEKilgELEHAQKAAHLAEQQ 834
Cdd:TIGR00618  544 --EEDVYHQLTSERKQRAS-LKEQMQEIQQSFSIltqcDNRSKEDIPNLQNITVRLQDLTEK---LSEAEDMLACEQHAL 617

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    835 LKEIKIQRDDYQK-----QKDEHARHLFDIRHKLETEI----------KGRQDLEKNGARNNDELDKL----RQTISDYE 895
Cdd:TIGR00618  618 LRKLQPEQDLQDVrlhlqQCSQELALKLTALHALQLTLtqervrehalSIRVLPKELLASRQLALQKMqsekEQLTYWKE 697

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 --SQINLLRRhndELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQA---------- 963
Cdd:TIGR00618  698 mlAQCQTLLR---ELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFnnneevtaal 774

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    964 -----LKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANL----LNKELEDTKQDLKHSTDVNKQLEQDIRDL 1034
Cdd:TIGR00618  775 qtgaeLSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLqcetLVQEEEQFLSRLEEKSATLGEITHQLLKY 854


                   ....
gi 25151529   1035 KERL 1038
Cdd:TIGR00618  855 EECS 858
PRK10361 PRK10361
DNA recombination protein RmuC; Provisional
 1360-1520 1.49e-04

DNA recombination protein RmuC; Provisional


Pssm-ID: 182409 [Multi-domain]  Cd Length: 475  Bit Score: 46.90  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1360 QVRHLEDELADtkgnlvQKEMDLESTQNRLRSLEDQHstlqsdankWRGELDAALRENDILKSNNTNMETDLTRLKNRLK 1439
Cdd:PRK10361   27 HAQQKAEQLAE------REEMVAELSAAKQQITQSEH---------WRAECELLNNEVRSLQSINTSLEADLREVTTRME 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1440 S----AEDALKELKNSLSHAKTEKERLQN-AFREKTKQADH-----LNQLASQFDTKLTKLRNELQDTNDKlitSDTERN 1509
Cdd:PRK10361   92 AaqqhADDKIRQMINSEQRLSEQFENLANrIFEHSNRRVDEqnrqsLNSLLSPLREQLDGFRRQVQDSFGK---EAQERH 168

                         170
                  ....*....|.
gi 25151529  1510 ALRNELQKLSQ 1520
Cdd:PRK10361  169 TLAHEIRNLQQ 179
46 PHA02562
endonuclease subunit; Provisional
 741-986 1.82e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   741 NRR--VENLL------RENNRLKSEVNPLKDKYRDLENEYNSTQRRIEekeTQIRYSDDIRRNIQKDLDDLREKYDRvHT 812
Cdd:PHA02562  151 ARRklVEDLLdisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIK---TYNKNIEEQRKKNGENIARKQNKYDE-LV 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   813 DNEKILgeleHAQKAahLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGarnndELDKLRQTIS 892
Cdd:PHA02562  227 EEAKTI----KAEIE--ELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGG-----VCPTCTQQIS 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   893 DYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILN--------QKL--KLDGDVQ 962
Cdd:PHA02562  296 EGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITlvdkakkvKAAieELQAEFV 375

                         250       260
                  ....*....|....*....|....
gi 25151529   963 ALKETIRKLENELEKLRNENKELV 986
Cdd:PHA02562  376 DNAEELAKLQDELDKIVKTKSELV 399
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1835-2193 1.82e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1835 LQARGKEAQLRHLNE---QLKNLRTDLDNAHtdirSLRDKEEQW-DSSRFQLETKMRE----SDSDTNKYQLQIASFESE 1906
Cdd:pfam15921   68 IAYPGKEHIERVLEEyshQVKDLQRRLNESN----ELHEKQKFYlRQSVIDLQTKLQEmqmeRDAMADIRRRESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1907 RQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRkTIDIQSKTSHEYQLLKDQLLNTQNelngANNR 1986
Cdd:pfam15921  144 RNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIR-SILVDFEEASGKKIYEHDSMSTMH----FRSL 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1987 KQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDA-----NTEKNRVEdRFLSVEKV--------VNTMRTTETDL 2053
Cdd:pfam15921  219 GSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKielllQQHQDRIE-QLISEHEVeitgltekASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2054 RQQL----ETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDG--WKKEKITLLKKIELLENEKRRtDAAIRETALQR 2127
Cdd:pfam15921  298 QSQLeiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDkiEELEKQLVLANSELTEARTER-DQFSQESGNLD 376

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   2128 EAIEKSLNAMERENKELyknCAQLQQQIAQLEMENGNRIL------ELTNKQREEQ--ERQLIRMRQE-KGQIEK 2193
Cdd:pfam15921  377 DQLQKLLADLHKREKEL---SLEKEQNKRLWDRDTGNSITidhlrrELDDRNMEVQrlEALLKAMKSEcQGQMER 448
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1727-2134 1.96e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1727 NGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTInqkETRYRNIEDNLQDAEEERRALESRLQSAK 1806
Cdd:COG4913  335 NGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAAALLEALEEELEALEEALAEAE 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1807 TLLRSQEEALKQRDEERRQMKSKMV---AAELQARgkeaqlRHLNEQLKNLRTDLDNA--HTDIRslrDKEEQW------ 1875
Cdd:COG4913  412 AALRDLRRELRELEAEIASLERRKSnipARLLALR------DALAEALGLDEAELPFVgeLIEVR---PEEERWrgaier 482

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1876 -----------------DSSRF----QLETKMRESDSDTNKYQLQIASFESERqiLTEKikeldgaLRLSDSKVQDMKDD 1934
Cdd:COG4913  483 vlggfaltllvppehyaAALRWvnrlHLRGRLVYERVRTGLPDPERPRLDPDS--LAGK-------LDFKPHPFRAWLEA 553

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1935 TDKLRRDLTKAESVEnELRK-----TIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQ--QLENELLNVRSEVRDYKQR 2007
Cdd:COG4913  554 ELGRRFDYVCVDSPE-ELRRhpraiTRAGQVKGNGTRHEKDDRRRIRSRYVLGFDNRAKlaALEAELAELEEELAEAEER 632

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2008 VHDVNNRVSELQRQLQDANTEKNRVEDRfLSVEKVVNTMRTTETD-------------LRQQLETAKNEKRVATKELEDL 2074
Cdd:COG4913  633 LEALEAELDALQERREALQRLAEYSWDE-IDVASAEREIAELEAElerldassddlaaLEEQLEELEAELEELEEELDEL 711

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2075 KRRLAQLENERRNSSQLsdgwKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSL 2134
Cdd:COG4913  712 KGEIGRLEKELEQAEEE----LDELQDRLEAAEDLARLELRALLEERFAAALGDAVEREL 767
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 615-954 2.11e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 46.74  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    615 DIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKsvdeaerNSRRTDDKLRASEAERVAAEKARK 694
Cdd:pfam10174  381 EIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQT-------DSSNTDTALTTLEEALSEKERIIE 453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    695 FLEDELAKLQASFQKSStDDARKLRDEMDEHTNSIQEEF---KTRIDELNRRVENL----LRENNRLKS---EVNPLKDK 764
Cdd:pfam10174  454 RLKEQREREDRERLEEL-ESLKKENKDLKEKVSALQPELtekESSLIDLKEHASSLassgLKKDSKLKSleiAVEQKKEE 532

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    765 YRDLENEYNSTQRRIEEKETQIRYSDDIrRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKiqrDD 844
Cdd:pfam10174  533 CSKLENQLKKAHNAEEAVRTNPEINDRI-RLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELE---SL 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    845 YQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISdYESQINLLRRHNDELDTTikghQGKITHLEN 924
Cdd:pfam10174  609 TLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQ-LEELMGALEKTRQELDAT----KARLSSTQQ 683

                          330       340       350
                   ....*....|....*....|....*....|
gi 25151529    925 ELHSRSGEiekLNDLNQRLQKEKQDILNQK 954
Cdd:pfam10174  684 SLAEKDGH---LTNLRAERRKQLEEILEMK 710
PRK11281 PRK11281
mechanosensitive channel MscK;
1315-1598 2.34e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 46.83  E-value: 2.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1315 VRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSqVRHLEDELADTkgnlvqkEMDLESTQNRLRSLED 1394
Cdd:PRK11281   78 QKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLS-LRQLESRLAQT-------LDQLQNAQNDLAEYNS 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1395 QHSTLQSDANKWRGELDAALRE----NDILKSNNTNMETDLTRLKNRLkSAEDALKELKNSLSHAKTE-KERLQNAFrek 1469
Cdd:PRK11281  150 QLVSLQTQPERAQAALYANSQRlqqiRNLLKGGKVGGKALRPSQRVLL-QAEQALLNAQNDLQRKSLEgNTQLQDLL--- 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1470 TKQADHLNQLASQFDTKLTKLRNELqdtNDKLITSdTERNALRNELQKLSQELKfGNEQIQRksdeyqttidDLAHSHRV 1549
Cdd:PRK11281  226 QKQRDYLTARIQRLEHQLQLLQEAI---NSKRLTL-SEKTVQEAQSQDEAARIQ-ANPLVAQ----------ELEINLQL 290

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 25151529  1550 SEDsRLNALQELearkyeiNDLTSRLDSTEQRLATLQQdyikadSERDI 1598
Cdd:PRK11281  291 SQR-LLKATEKL-------NTLTQQNLRVKNWLDRLTQ------SERNI 325
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 600-1036 2.44e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.50  E-value: 2.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    600 EALRAVRNTFRNKDNDIQQLERKlKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKL 679
Cdd:TIGR00618  466 QSLKEREQQLQTKEQIHLQETRK-KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    680 RASEAERVAAEKARKFLEDELAKLQASFQKSSTDDARkLRDEMDEHTNsIQEEFKTRIDELNRRVENLLRENNRLKSEVN 759
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNR-SKEDIPNLQN-ITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    760 PLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRniqkdlDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIK 839
Cdd:TIGR00618  623 PEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ------ERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWK 696

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    840 iqrddyqkqkdEHARHLFDIRHKLETEIKgrqdlekngarnndELDKLRQTISD-YESQINLLRRHNDELDTTIKGHQG- 917
Cdd:TIGR00618  697 -----------EMLAQCQTLLRELETHIE--------------EYDREFNEIENaSSSLGSDLAAREDALNQSLKELMHq 751

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    918 ---KITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENEL---EKLRNENKELVGKEAR 991
Cdd:TIGR00618  752 artVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIpsdEDILNLQCETLVQEEE 831

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 25151529    992 ardaanQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKE 1036
Cdd:TIGR00618  832 ------QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 515-775 2.48e-04

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 45.02  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    515 KELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEknvdgtvsikrtrslspgkt 594
Cdd:pfam00261   18 KEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKLEEAEKAADESE-------------------- 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    595 plppsEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFEnadEARRRLdkqfadakreisnlqksvDEAERNSRR 674
Cdd:pfam00261   78 -----RGRKVLENRALKDEEKMEILEAQLKEAKEIAEEADRKYE---EVARKL------------------VVVEGDLER 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    675 TDDKLRASEAERVAAEKARKFLEDELAKLQASFQKSStddarKLRDEMDEHTNSIQEEFK---TRIDELNRRVENLLREN 751
Cdd:pfam00261  132 AEERAELAESKIVELEEELKVVGNNLKSLEASEEKAS-----EREDKYEEQIRFLTEKLKeaeTRAEFAERSVQKLEKEV 206

                          250       260
                   ....*....|....*....|....
gi 25151529    752 NRLKSEVNPLKDKYRDLENEYNST 775
Cdd:pfam00261  207 DRLEDELEAEKEKYKAISEELDQT 230
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1365-1729 2.54e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1365 EDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDA 1444
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1445 LKELKNSLSHAktekERLQNA--FREKTKQADHLNQLASQFDTKLtklrNELQDTNDKLITSDTERNALRNELQKLSQEL 1522
Cdd:COG3883   95 LYRSGGSVSYL----DVLLGSesFSDFLDRLSALSKIADADADLL----EELKADKAELEAKKAELEAKLAELEALKAEL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1523 KFGNEQIQRKSDEYQTTIDDLAhshrVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDA 1602
Cdd:COG3883  167 EAAKAELEAQQAEQEALLAQLS----AEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1603 LRrfQSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSD 1682
Cdd:COG3883  243 AA--SAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASGGSGGGSGGAGGVGSGGGAG 320

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 25151529 1683 QSDVAYPRSVPFPPSADFSSGRPGAASAGGRVINNLDGTTTVNMNGG 1729
Cdd:COG3883  321 AVVGGASAGGGGGSGGGGGSSGGGSGGGGGGGGGGGGSSSGGGGGGV 367
46 PHA02562
endonuclease subunit; Provisional
 693-954 2.56e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   693 RKFLEDELA-KLQASFQKSSTDDARKLRDE---MDEHTNSIQEEFKTRIDELNRrvenlLRENNrlKSEVNPLKDKYRDL 768
Cdd:PHA02562  153 RKLVEDLLDiSVLSEMDKLNKDKIRELNQQiqtLDMKIDHIQQQIKTYNKNIEE-----QRKKN--GENIARKQNKYDEL 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   769 ENEYNSTQRRIEEKETQIRysddirrNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAE---------QQLKEik 839
Cdd:PHA02562  226 VEEAKTIKAEIEELTDELL-------NLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEkggvcptctQQISE-- 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   840 iQRDDYQKQKDEharhLFDIRHKLETEIKGRQDLEKNgarnNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKI 919
Cdd:PHA02562  297 -GPDRITKIKDK----LKELQHSLEKLDTAIDELEEI----MDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI 367

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 25151529   920 THLENELHSRSGEIEKLNDLNQRLQKEKQDILNQK 954
Cdd:PHA02562  368 EELQAEFVDNAEELAKLQDELDKIVKTKSELVKEK 402
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1747-2074 2.64e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1747 EKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALK-------QR 1819
Cdd:pfam07888   69 EQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKtltqrvlER 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1820 DEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQ 1899
Cdd:pfam07888  149 ETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRK 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1900 IASFESerqiLTEKIKELDGALRLSDSKVQDMKDDTDKL--RRDLTKAEsvenelrktidiqsktSHEYQLLKDQLLNTQ 1977
Cdd:pfam07888  229 EAENEA----LLEELRSLQERLNASERKVEGLGEELSSMaaQRDRTQAE----------------LHQARLQAAQLTLQL 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1978 NELN-----GANNRKQQLENELLNVRSEvrdyKQRVHDVNNRVSELQRQLQDANTEKNRVEDRfLSVEKVVNTMRTTETd 2052
Cdd:pfam07888  289 ADASlalreGRARWAQERETLQQSAEAD----KDRIEKLSAELQRLEERLQEERMEREKLEVE-LGREKDCNRVQLSES- 362

                          330       340
                   ....*....|....*....|..
gi 25151529   2053 lRQQLETAKNEKRVATKELEDL 2074
Cdd:pfam07888  363 -RRELQELKASLRVAQKEKEQL 383
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 515-705 2.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  515 KELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLH-EMAQDSEKNVDGTVSIKRTRSLSPGK 593
Cdd:COG4942   44 AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRaELEAQKEELAELLRALYRLGRQPPLA 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  594 TPLPPSEALRAVRNT------FRNKDNDIQQLERKLKIAESQVKEflnkfenADEARRRLDKQFADAKREISNLQKSVDE 667
Cdd:COG4942  124 LLLSPEDFLDAVRRLqylkylAPARREQAEELRADLAELAALRAE-------LEAERAELEALLAELEEERAALEALKAE 196

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 25151529  668 AERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQA 705
Cdd:COG4942  197 RQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 1730-1974 2.80e-04

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 46.22  E-value: 2.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1730 FDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEE----ERRALESRLQSA 1805
Cdd:pfam05622  211 FEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAELSQADALLSPSSDPGDNLAAEimpaEIREKLIRLQHE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1806 KTLLR-SQEEALKQRDEERRQMkskMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLET 1884
Cdd:pfam05622  291 NKMLRlGQEGSYRERLTELQQL---LEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEE 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1885 ---KMRESDSDTNKYQLQIASFESERQI-LTEKIKELDGALRLSDskvQDMKDDTDKLRRDLTKAESVenelRKTID--I 1958
Cdd:pfam05622  368 hleKLHEAQSELQKKKEQIEELEPKQDSnLAQKIDELQEALRKKD---EDMKAMEERYKKYVEKAKSV----IKTLDpkQ 440

                          250
                   ....*....|....*.
gi 25151529   1959 QSKTSHEYQLLKDQLL 1974
Cdd:pfam05622  441 NPASPPEIQALKNQLL 456
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 1801-2081 2.97e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 46.00  E-value: 2.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1801 RLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNlrtDLDNAhtdiRSLRDKEEQwdsSRF 1880
Cdd:pfam09726  399 RLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSLKSELGQLRQENDLLQT---KLHNA----VSAKQKDKQ---TVQ 468

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1881 QLETKMRESDSDTNKYQLQIASfESERqilteKIKELDGALRLSDSKVQDMKDDTDKLRRdltKAESVENELRKTidiqs 1960
Cdd:pfam09726  469 QLEKRLKAEQEARASAEKQLAE-EKKR-----KKEEEATAARAVALAAASRGECTESLKQ---RKRELESEIKKL----- 534

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1961 ktSHEYQLLKDQLlntqnelngannrkQQLENELlnvrSEVRDYKQRVHDVNNRVSELQrqlqdANTEKNRVEDRFLSVE 2040
Cdd:pfam09726  535 --THDIKLKEEQI--------------RELEIKV----QELRKYKESEKDTEVLMSALS-----AMQDKNQHLENSLSAE 589

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 25151529   2041 KVVN-TMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQL 2081
Cdd:pfam09726  590 TRIKlDLFSALGDAKRQLEIAQGQIYQKDQEIKDLKQKIAEV 631
PRK12705 PRK12705
hypothetical protein; Provisional
 887-1041 3.05e-04

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 45.86  E-value: 3.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   887 LRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRsgEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKE 966
Cdd:PRK12705   39 LQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQR--EEERLVQKEEQLDARAEKLDNLENQLEEREKALSA 116

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   967 TIRKLENELEKLRNENKELVGKEaraRDAANQQLsrANLLNKELEDTKQDLKhstdvnKQLEQDIRDLKERLANI 1041
Cdd:PRK12705  117 RELELEELEKQLDNELYRVAGLT---PEQARKLL--LKLLDAELEEEKAQRV------KKIEEEADLEAERKAQN 180
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 512-1034 3.37e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    512 ELHKELMTKYEESIER----NIELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKnvdgtvSIKRTR 587
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRsqllTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEE------QLKKQQ 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    588 SLSPGKTPLPPSEALRAVRNTFRNKDNDIQQLERKLKIAESqVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDE 667
Cdd:TIGR00618  261 LLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKA-VTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSS 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    668 AERNSRRTDDKLRASEAERVAAEKARKFLEdelaklQASFQKSSTDDARKLRD--EMDEHTNSIQEEFKTRIDELNRRVE 745
Cdd:TIGR00618  340 IEEQRRLLQTLHSQEIHIRDAHEVATSIRE------ISCQQHTLTQHIHTLQQqkTTLTQKLQSLCKELDILQREQATID 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    746 NLLRENNRLKSEVNPLKdKYRDLENEYNSTQRRIEEKETQI-----------RYSDDIRRNIQKDLDDLREKYDRVHTDN 814
Cdd:TIGR00618  414 TRTSAFRDLQGQLAHAK-KQQELQQRYAELCAAAITCTAQCeklekihlqesAQSLKEREQQLQTKEQIHLQETRKKAVV 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    815 EKILGELEHAQKA-------AHLAEQQLKEIKIQRDDYQKQKDEHARH---LFDIRHKLETEIKGRQDLEKNGARNNDEL 884
Cdd:TIGR00618  493 LARLLELQEEPCPlcgscihPNPARQDIDNPGPLTRRMQRGEQTYAQLetsEEDVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    885 DKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSrsgEIEKLNDlnqrlQKEKQDILNQKLKLDGDVQAL 964
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHA---LLRKLQP-----EQDLQDVRLHLQQCSQELALK 644

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529    965 KETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNK--ELEDTKQDLKHSTDVNKQLEQDIRDL 1034
Cdd:TIGR00618  645 LTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEkeQLTYWKEMLAQCQTLLRELETHIEEY 716
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 834-1042 3.53e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.66  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    834 QLKEIKIQRDDYQKQKDEHARHLFDIRHK-LETEIkgrQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTI 912
Cdd:pfam07888   48 QAQEAANRQREKEKERYKRDREQWERQRReLESRV---AELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQR 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    913 KGHQGKITHLENELHS-------RSGEIEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKEL 985
Cdd:pfam07888  125 AAHEARIRELEEDIKTltqrvleRETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQR 204

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    986 VGKEARARDAAN---QQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIG 1042
Cdd:pfam07888  205 DTQVLQLQDTITtltQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMA 264
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1784-2221 3.73e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.10  E-value: 3.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1784 IEDNLQDAE----EERRALEsrlqsAKTLLRSQEEALKQRDEErrqmKSKMVAAelqargkeAQLRHLNEQLKNLRTDLD 1859
Cdd:COG3096  227 VRKAFQDMEaalrENRMTLE-----AIRVTQSDRDLFKHLITE----ATNYVAA--------DYMRHANERRELSERALE 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1860 NAhtdiRSLRDKEEQWDSSRFQLETKMRESDsdtnKYQLQIASFESERQILTEKIKELDGALRLSDsKVQDMKDDTDKLR 1939
Cdd:COG3096  290 LR----RELFGARRQLAEEQYRLVEMARELE----ELSARESDLEQDYQAASDHLNLVQTALRQQE-KIERYQEDLEELT 360

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1940 RDLTKAESVENELRKTIDIQSKTSH----EYQLLKDQLLNTQNELNGANNR--------------KQQLENELL---NVR 1998
Cdd:COG3096  361 ERLEEQEEVVEEAAEQLAEAEARLEaaeeEVDSLKSQLADYQQALDVQQTRaiqyqqavqalekaRALCGLPDLtpeNAE 440

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1999 SEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETD--LRQQLETAKNEKRVATK------E 2070
Cdd:COG3096  441 DYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWqtARELLRRYRSQQALAQRlqqlraQ 520

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2071 LEDLKRRLAQLENERRNSSQLSDGWKKEkitlLKKIELLENEKRRTDAAIRE-TALQREAIEKsLNAMERENKELyknca 2149
Cdd:COG3096  521 LAELEQRLRQQQNAERLLEEFCQRIGQQ----LDAAEELEELLAELEAQLEElEEQAAEAVEQ-RSELRQQLEQL----- 590

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2150 qlqqqiaqlemenGNRILELTNKQ---REEQERqLIRMRQEKGQI----EKVIENRERTHRN--RIKQLEDQIAILRDQL 2220
Cdd:COG3096  591 -------------RARIKELAARApawLAAQDA-LERLREQSGEAladsQEVTAAMQQLLERerEATVERDELAARKQAL 656


                 .
gi 25151529 2221 D 2221
Cdd:COG3096  657 E 657
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1971-2357 3.78e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1971 DQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTE----KNRVEDRFLSVEKVVNTM 2046
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaeaEAEIEERREELGERARAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2047 RTTETDLR--QQLETAKNekrvatkeLEDLKRRLAQLenerrnsSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETA 2124
Cdd:COG3883   96 YRSGGSVSylDVLLGSES--------FSDFLDRLSAL-------SKIADADADLLEELKADKAELEAKKAELEAKLAELE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2125 LQREAIEKSLNAMERENKELykncaqlqqqiaqlemengNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRN 2204
Cdd:COG3883  161 ALKAELEAAKAELEAQQAEQ-------------------EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2205 RIKQLEDQIAILRDQLDGERRRRREYVDRSMVNDIGRLGSNVLGIRNSYGDNSIDAIINGGSRSVGFYPRSTFASNPLTP 2284
Cdd:COG3883  222 AAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASG 301

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2285 PLGSSTPTHRPHVTDFRSAVDAGSSYRRPISTIEDSGSVYGGSIRDRDSVYGGGGRDSSFGTRAGDSISRAGV 2357
Cdd:COG3883  302 GSGGGSGGAGGVGSGGGAGAVVGGASAGGGGGSGGGGGSSGGGSGGGGGGGGGGGGSSSGGGGGGVGLSVGGG 374
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1181-2207 3.81e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 3.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1181 EDELSQIGRGNDKTENDITELKRKHAaeidKLKSDISALHDKhlsdLDDEKEQYGKAVE---NLKSVEDDLRDKLNNLEK 1257
Cdd:pfam01576   11 EEELQKVKERQQKAESELKELEKKHQ----QLCEEKNALQEQ----LQAETELCAEAEEmraRLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1258 QLADSLNRENELEREKRDYDEKINSLYGQnqkiKDEWDDFRNDAdkEIQKWKTDAYTVRSEAK--ALETTNTALKAQLQA 1335
Cdd:pfam01576   83 RLEEEEERSQQLQNEKKKMQQHIQDLEEQ----LDEEEAARQKL--QLEKVTTEAKIKKLEEDilLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1336 ANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDAnkwrGELDAALR 1415
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI----AELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1416 EndiLKSNNTNMETDLTRLKNRLK-------SAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQlasqfdtKLT 1488
Cdd:pfam01576  233 E---LRAQLAKKEEELQAALARLEeetaqknNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE-------ELE 302

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1489 KLRNELQDTNDKLITSD---TERNALRNELQK-LSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNALQELEAR 1564
Cdd:pfam01576  303 ALKTELEDTLDTTAAQQelrSKREQEVTELKKaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQAL 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1565 KYEINDLTSRLDSTEQRLATLQQDYIKADSERDIL----SDALRRFQSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGG 1640
Cdd:pfam01576  383 ESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqarlSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKD 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1641 PSAQRSGAYDPSSGGVIGSGISGGPGGSDfgREIEIGRG-------DSDQSDVAYPRSVPFPPSADFSSGRPGAASAGgr 1713
Cdd:pfam01576  463 VSSLESQLQDTQELLQEETRQKLNLSTRL--RQLEDERNslqeqleEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAG-- 538

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1714 vinNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQD--- 1790
Cdd:pfam01576  539 ---TLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEeka 615

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1791 -----AEEERRA-LESRLQSAK--TLLRSQEEALKQRDEERRQMKskMVAAELQA-------------------RGKEAQ 1843
Cdd:pfam01576  616 isaryAEERDRAeAEAREKETRalSLARALEEALEAKEELERTNK--QLRAEMEDlvsskddvgknvhelerskRALEQQ 693

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1844 LRHLNEQLKNLRTDLDNAHTDI---------------RSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQ 1908
Cdd:pfam01576  694 VEEMKTQLEELEDELQATEDAKlrlevnmqalkaqfeRDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKK 773

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1909 ILTEKIKEL----DGALRLSDSKVQDMKD---DTDKLRRDLTKAESVenelRKTIDIQSKTSH-EYQLLKDQLLNTQNEL 1980
Cdd:pfam01576  774 KLELDLKELeaqiDAANKGREEAVKQLKKlqaQMKDLQRELEEARAS----RDEILAQSKESEkKLKNLEAELLQLQEDL 849

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1981 NGANNRKQQLENELLNVRSEV----------RDYKQRVHDvnnRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTE 2050
Cdd:pfam01576  850 AASERARRQAQQERDELADEIasgasgksalQDEKRRLEA---RIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTEL 926

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2051 TDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKkiELLENEK----------RRTDAAI 2120
Cdd:pfam01576  927 AAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLE--EQLEQESrerqaanklvRRTEKKL 1004

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2121 RETALQREAiekslnamERENKELYKncaqlqqqiaqlemengnrileltnkqrEEQERQLIRMRQEKGQIEKVIENRER 2200
Cdd:pfam01576 1005 KEVLLQVED--------ERRHADQYK----------------------------DQAEKGNSRMKQLKRQLEEAEEEASR 1048


                   ....*..
gi 25151529   2201 THRNRIK 2207
Cdd:pfam01576 1049 ANAARRK 1055
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
792-1214 3.93e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  792 IRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLEteikgRQ 871
Cdd:COG4717   47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-----KL 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  872 DLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKghqgKITHLENELHSRSGEI-EKLNDLNQRLQKEKQDI 950
Cdd:COG4717  122 EKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEE----ELEELEAELAELQEELeELLEQLSLATEEELQDL 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  951 LNQKLKLDGDVQALKETIRKLENELEKLRNENKELvgKEARARDAANQQLSRANLL------------------------ 1006
Cdd:COG4717  198 AEELEELQQRLAELEEELEEAQEELEELEEELEQL--ENELEAAALEERLKEARLLlliaaallallglggsllslilti 275

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1007 --------------------NKELEDTKQDLKHSTDVNKQLEQdiRDLKERLANIGKGGRISRDSTTGtdggAFGDRSSV 1066
Cdd:COG4717  276 agvlflvlgllallflllarEKASLGKEAEELQALPALEELEE--EELEELLAALGLPPDLSPEELLE----LLDRIEEL 349

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1067 ADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIH-GRDGRDGRDAGNRgthtITNTKERIERIEKNILD--RYH 1143
Cdd:COG4717  350 QELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAaLEQAEEYQELKEE----LEELEEQLEELLGELEEllEAL 425

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25151529 1144 DDELVEHKIREVndrwKRELERLENEKDDLERRIRELEDELSQIGrgndkTENDITELKRKHAAEIDKLKS 1214
Cdd:COG4717  426 DEEELEEELEEL----EEELEELEEELEELREELAELEAELEQLE-----EDGELAELLQELEELKAELRE 487
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 506-1039 3.97e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    506 SSEGDAELHKELMTKYEESIERNIELESRGDDSQRKIAELEAEL------RRNREKLNEA---------QGALKKLHEMA 570
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIkalksrKKQMEKDNSElelkmekvfQGTDEQLNDLY 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    571 QD--------SEKNVDGTVSI----KRTRSLSPGKTPLppseALRAVRNTFRNKDNDIQQLERKLKIAESQVKEFLNKFE 638
Cdd:TIGR00606  308 HNhqrtvrekERELVDCQRELeklnKERRLLNQEKTEL----LVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    639 NAdearrrldkqfADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVA-AEKARKFLEDELAKLQASFQKSS------ 711
Cdd:TIGR00606  384 RG-----------PFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERlKQEQADEIRDEKKGLGRTIELKKeilekk 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    712 TDDARKLRDEMDEHTNS------IQEEFKTRIDELNRRVENLLRENnrLKSEVNPLKDKYRDLENeynsTQRRIEEKETQ 785
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSsdrileLDQELRKAERELSKAEKNSLTET--LKKEVKSLQNEKADLDR----KLRKLDQEMEQ 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    786 IRYSDDIRRNIQKDLDDLREKYDRVHTDNEK-------ILGELEHAQKAAHLAEQQLKEIKIQRDDYQK-----QKDEHA 853
Cdd:TIGR00606  527 LNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRhsdeltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKlnkelASLEQN 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    854 RHLFDIRHKLETE-----------IKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDT------------ 910
Cdd:TIGR00606  607 KNHINNELESKEEqlssyedklfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDenqsccpvcqrv 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    911 --TIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILnqklkldGDVQALKETIRKLENELEKLRNENKELVGK 988
Cdd:TIGR00606  687 fqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEML-------GLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 25151529    989 EARARDAANQQLSRANLLNKELEDTKqDLKHSTDVNKQLEQDIRDLKERLA 1039
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAK-VCLTDVTIMERFQMELKDVERKIA 809
46 PHA02562
endonuclease subunit; Provisional
 833-1036 4.12e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 4.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   833 QQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIkgrqdlekngARNNDELDKLRQTISDYESQINLLrrhNDEldtti 912
Cdd:PHA02562  181 QQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENI----------ARKQNKYDELVEEAKTIKAEIEEL---TDE----- 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   913 kghqgkITHLENELHSRSGEIEKLNDLNQRLqKEKQDILNQKLKL--DGDV-QALKETIRKLENELEKLRNENKEL---- 985
Cdd:PHA02562  243 ------LLNLVMDIEDPSAALNKLNTAAAKI-KSKIEQFQKVIKMyeKGGVcPTCTQQISEGPDRITKIKDKLKELqhsl 315

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529   986 ------VGKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKE 1036
Cdd:PHA02562  316 ekldtaIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQA 372
PTZ00121 PTZ00121
MAEBL; Provisional
 1791-2113 4.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1791 AEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRD 1870
Cdd:PTZ00121 1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1871 KEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGAlrlsdSKVQDMKDDTDKLRRdltKAESV-- 1948
Cdd:PTZ00121 1652 LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA-----KKAEELKKKEAEEKK---KAEELkk 1723

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1949 ENELRKTIDIQSKTSHEYQLLKDQLLNTQnelNGANNRKQQLENELLNVRSEVRDYKQRV------HDVNNRVSELQRQL 2022
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKD---EEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEKRRMEVDKKI 1800

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2023 QDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDgwkKEKITL 2102
Cdd:PTZ00121 1801 KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN---KEKDLK 1877

                         330
                  ....*....|.
gi 25151529  2103 LKKIELLENEK 2113
Cdd:PTZ00121 1878 EDDEEEIEEAD 1888
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1738-2144 4.39e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 4.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1738 TLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERraleSRLQSAKTLLRSQEEALK 1817
Cdd:TIGR00606  204 EHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNL----SKIMKLDNEIKALKSRKK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1818 QRDEERRQMKSKMVAAelqARGKEAQLRHLNE----QLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDT 1893
Cdd:TIGR00606  280 QMEKDNSELELKMEKV---FQGTDEQLNDLYHnhqrTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1894 NKYQLQIASFESERQILTEKIkELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQL 1973
Cdd:TIGR00606  357 DRHQEHIRARDSLIQSLATRL-ELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1974 LNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQD-------ANTEKNRVEDRFLSVEKVvnTM 2046
Cdd:TIGR00606  436 KGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERElskaeknSLTETLKKEVKSLQNEKA--DL 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2047 RTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSD------GWKKEKITLLKKIELLENEKRRTDAAI 2120
Cdd:TIGR00606  514 DRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDeltsllGYFPNKKQLEDWLHSKSKEINQTRDRL 593

                          410       420
                   ....*....|....*....|....
gi 25151529   2121 RETALQREAIEKSLNAMERENKEL 2144
Cdd:TIGR00606  594 AKLNKELASLEQNKNHINNELESK 617
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 810-1041 4.93e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.30  E-value: 4.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   810 VHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKdeharhlfdIRHKLETEIKgRQDLEKNGARNNDELDKLRQ 889
Cdd:PRK05771   31 VHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLN---------PLREEKKKVS-VKSLEELIKDVEEELEKIEK 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   890 TISDYESQINllrrhndELDTTIKGHQGKITHLE----------NELHSRS-----GEIEKLNDLNQRLQKEKQDILNQK 954
Cdd:PRK05771  101 EIKELEEEIS-------ELENEIKELEQEIERLEpwgnfdldlsLLLGFKYvsvfvGTVPEDKLEELKLESDVENVEYIS 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   955 LKLDGD---VQALKETIRKLENELEKLRNENKELVGKEaRARDAANQQLSRANLLNKELEDTKQDLKhstDVNKQLEQDI 1031
Cdd:PRK05771  174 TDKGYVyvvVVVLKELSDEVEEELKKLGFERLELEEEG-TPSELIREIKEELEEIEKERESLLEELK---ELAKKYLEEL 249

                         250
                  ....*....|
gi 25151529  1032 RDLKERLANI 1041
Cdd:PRK05771  250 LALYEYLEIE 259
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 656-1341 5.03e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.48  E-value: 5.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    656 REISNLQKSVDEAERNSRRTDDKLRASEAErvaAEKARKFLEDELAKLQaSFQKSSTDDARKLRDEMDEHTNSIQEEFKT 735
Cdd:pfam05483   78 RLYSKLYKEAEKIKKWKVSIEAELKQKENK---LQENRKIIEAQRKAIQ-ELQFENEKVSLKLEEEIQENKDLIKENNAT 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    736 R--IDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSD-DIRRNIQKD---LDDLREKYDR 809
Cdd:pfam05483  154 RhlCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARlEMHFKLKEDhekIQHLEEEYKK 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    810 VHTDNEKILG-------ELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKGRQDLEKNGARNND 882
Cdd:pfam05483  234 EINDKEKQVSllliqitEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQK 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    883 ELDK--------LRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLND----LNQRLQKEKQDi 950
Cdd:pfam05483  314 ALEEdlqiatktICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDqlkiITMELQKKSSE- 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    951 LNQKLKLDGDVQALKETIRKLENELEKLRNENKElVGKEARARDAANQQLS-RANLLNKELEDTKQDLKHSTDVNKQLEQ 1029
Cdd:pfam05483  393 LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQ-FEKIAEELKGKEQELIfLLQAREKEIHDLEIQLTAIKTSEEHYLK 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1030 DIRDLKERLANigkggrisrDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDiesrgggeidipssgdvihgrd 1109
Cdd:pfam05483  472 EVEDLKTELEK---------EKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQE---------------------- 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1110 grdgrdagnrgthTITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGR 1189
Cdd:pfam05483  521 -------------DIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEK 587

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1190 GNDKTENDITELKRK---HAAEIDKLKSDISALHDKHLSD---LDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADS- 1262
Cdd:pfam05483  588 QMKILENKCNNLKKQienKNKNIEELHQENKALKKKGSAEnkqLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKk 667

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1263 LNREN---ELEREKRDYDE--------------KINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETT 1325
Cdd:pfam05483  668 ISEEKlleEVEKAKAIADEavklqkeidkrcqhKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIE 747

                          730
                   ....*....|....*.
gi 25151529   1326 NTALKAQLQAANDRID 1341
Cdd:pfam05483  748 LSNIKAELLSLKKQLE 763
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1164-1467 5.18e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 5.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1164 ERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHAaeidklksdisalhdkhLSDLDDEKEQYgkaVENLks 1243
Cdd:COG3206  164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNG-----------------LVDLSEEAKLL---LQQL-- 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1244 veDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLygqnqkikdewddfrnDADKEIQkwktdaytvrseakale 1323
Cdd:COG3206  222 --SELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL----------------LQSPVIQ----------------- 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1324 ttntALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELAD-TKGNLVQKEMDLESTQNRLRSLEDQHSTLQSD 1402
Cdd:COG3206  267 ----QLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQeAQRILASLEAELEALQAREASLQAQLAQLEAR 342

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1403 ANKwrgeldaalrendilksnNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFR 1467
Cdd:COG3206  343 LAE------------------LPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 715-1014 5.19e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 45.23  E-value: 5.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    715 ARKLRDEMDEHTNSIQEEfktrIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNsTQR-----RIEEKETQIRY- 788
Cdd:pfam06160   84 AKKALDEIEELLDDIEED----IKQILEELDELLESEEKNREEVEELKDKYRELRKTLL-ANRfsygpAIDELEKQLAEi 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    789 ------------------SDDIRRNIQKDLDDLREKYDRV------------------------------HTDNEKILGE 820
Cdd:pfam06160  159 eeefsqfeeltesgdyleAREVLEKLEEETDALEELMEDIpplyeelktelpdqleelkegyremeeegyALEHLNVDKE 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    821 LEHAQKAAHLAEQQLKEIKIQR-----DDYQKQKDeharHLFDIrhkLETEIKGRQDLEKNGARNNDELDKLRQTisdye 895
Cdd:pfam06160  239 IQQLEEQLEENLALLENLELDEaeealEEIEERID----QLYDL---LEKEVDAKKYVEKNLPEIEDYLEHAEEQ----- 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    896 sqinllrrhNDELDTtikghqgKITHL-------ENELHSRSGEIEKLNDLNQRLQKEKQDILNQKL---KLDGDVQALK 965
Cdd:pfam06160  307 ---------NKELKE-------ELERVqqsytlnENELERVRGLEKQLEELEKRYDEIVERLEEKEVaysELQEELEEIL 370

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 25151529    966 ETIRKLENELEKLRNENKELVGKEARARDAANQqlsranlLNKELEDTK 1014
Cdd:pfam06160  371 EQLEEIEEEQEEFKESLQSLRKDELEAREKLDE-------FKLELREIK 412
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 490-1496 5.37e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.81  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    490 SSADLLEELRKIRGGGSSEGDA-ELHKELMTKYEESIERNIELesrgDDSQRKIAELEAELRRNREK--LNEAQGALKKL 566
Cdd:TIGR01612 1299 NISDIREKSLKIIEDFSEESDInDIKKELQKNLLDAQKHNSDI----NLYLNEIANIYNILKLNKIKkiIDEVKEYTKEI 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    567 HEmaqdSEKNVDGTVSiKRTRSLSPGKTPLPPSEALRAVRNTFRNKDND-----IQQLERKLKIAESQVKEFlnkFENAD 641
Cdd:TIGR01612 1375 EE----NNKNIKDELD-KSEKLIKKIKDDINLEECKSKIESTLDDKDIDecikkIKELKNHILSEESNIDTY---FKNAD 1446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    642 EARRRLDKQFADAKREiSNLQKSVDEAERNSRRTDDKLRASEAERvAAEKARKFledelaKLQASFQKSSTDDARKL--- 718
Cdd:TIGR01612 1447 ENNENVLLLFKNIEMA-DNKSQHILKIKKDNATNDHDFNINELKE-HIDKSKGC------KDEADKNAKAIEKNKELfeq 1518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    719 -RDEMDEHTNSIQE-EFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNI 796
Cdd:TIGR01612 1519 yKKDVTELLNKYSAlAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDI 1598

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    797 QKDLDDLREKYDRVHTDNEKILGELEHAQKaahlAEQQLKEIKIQRDDYQKQKDEharhlfDIRHKLETEIKGRQDLEKN 876
Cdd:TIGR01612 1599 QLSLENFENKFLKISDIKKKINDCLKETES----IEKKISSFSIDSQDTELKENG------DNLNSLQEFLESLKDQKKN 1668

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    877 GARNNDELDKLRQTISDYESQINLLRRhNDELDTTIKGHQGKITHlENELHSRSGEIE----------KLNDL-----NQ 941
Cdd:TIGR01612 1669 IEDKKKELDELDSEIEKIEIDVDQHKK-NYEIGIIEKIKEIAIAN-KEEIESIKELIEptienlissfNTNDLegidpNE 1746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    942 RLQK---EKQDILNQKLKLDGDVQALKETIRKLENELEKLRN-----ENKELVGKEARARDAANQQLSRANLLNKELEDT 1013
Cdd:TIGR01612 1747 KLEEyntEIGDIYEEFIELYNIIAGCLETVSKEPITYDEIKNtrinaQNEFLKIIEIEKKSKSYLDDIEAKEFDRIINHF 1826

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1014 KQDLKHstdVNKQLEQDIRDLKERLANIGKGGRISRDSTtgtdggafgDRSSVADP-SRTRGAAGSTV---FVPAAEDIE 1089
Cdd:TIGR01612 1827 KKKLDH---VNDKFTKEYSKINEGFDDISKSIENVKNST---------DENLLFDIlNKTKDAYAGIIgkkYYSYKDEAE 1894

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1090 SRGGGEIDIPSSGDV-IHGRDGRD-----------GRDAGNRGTHTITNTKERIERIEKNILDRYhdDELVEhKIREVND 1157
Cdd:TIGR01612 1895 KIFINISKLANSINIqIQNNSGIDlfdniniailsSLDSEKEDTLKFIPSPEKEPEIYTKIRDSY--DTLLD-IFKKSQD 1971

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1158 RWKRELERLE--NEKDDLERRIR---ELEDELSQIGRGNDKTENDITELKRKhAAEIDKLKSDiSALHDK--HLSDLDDE 1230
Cdd:TIGR01612 1972 LHKKEQDTLNiiFENQQLYEKIQasnELKDTLSDLKYKKEKILNDVKLLLHK-FDELNKLSCD-SQNYDTilELSKQDKI 2049

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1231 KEQ---YGKAVENLKSVED--DLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRND----A 1301
Cdd:TIGR01612 2050 KEKidnYEKEKEKFGIDFDvkAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEikiiE 2129

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1302 DKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAAN------------------DRIDHLTKTVNDHTSKVR---DLTSQ 1360
Cdd:TIGR01612 2130 DKIIEKNDLIDKLIEMRKECLLFSYATLVETLKSKVinhsefitsaakfskdffEFIEDISDSLNDDIDALQikyNLNQT 2209

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1361 VRHLEDELADT---KGNLVQKEMDLESTQNRLRSLedqhstLQSDANKwrgeLDAalrenDILKSNNTNMetdlTRLKNR 1437
Cdd:TIGR01612 2210 KKHMISILADAtkdHNNLIEKEKEATKIINNLTEL------FTIDFNN----ADA-----DILHNNKIQI----IYFNSE 2270

                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1438 LKSAEDALKELKNSLSHAKTEKERLQNA-FREKTKQADHLNQLASQfdtKLTKLRNELQD 1496
Cdd:TIGR01612 2271 LHKSIESIKKLYKKINAFKLLNISHINEkYFDISKEFDNIIQLQKH---KLTENLNDLKE 2327
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1312-1607 5.40e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 5.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1312 AYTVRSEAKALETTNTALKA-QLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELAD--TKGNLVQKEMDLESTQNR 1388
Cdd:COG3206  141 SYTSPDPELAAAVANALAEAyLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQ 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1389 LRSLEDQHSTLQSDANkwrgELDAALRendilksnntnmetdltRLKNRLKSAEDALKELKNSlshaktekERLQNAfre 1468
Cdd:COG3206  221 LSELESQLAEARAELA----EAEARLA-----------------ALRAQLGSGPDALPELLQS--------PVIQQL--- 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1469 ktkqadhLNQLAsQFDTKLTKLRNELQDTNDKLItsdternALRNELQKLSQELKfgnEQIQRKSDEYQTTIDDLAhshr 1548
Cdd:COG3206  269 -------RAQLA-ELEAELAELSARYTPNHPDVI-------ALRAQIAALRAQLQ---QEAQRILASLEAELEALQ---- 326

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529 1549 vsedsrlNALQELEARKYEINDLTSRLDSTEQRLATLQQDYikaDSERDILSDALRRFQ 1607
Cdd:COG3206  327 -------AREASLQAQLAQLEARLAELPELEAELRRLEREV---EVARELYESLLQRLE 375
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1176-1390 5.56e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1176 RIRELEDELSQIgrgndktENDITELKRkhaaEIDKLKSDISALHDKhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNL 1255
Cdd:COG4942   21 AAAEAEAELEQL-------QQEIAELEK----ELAALKKEEKALLKQ-LAALERRIAALARRIRALEQELAALEAELAEL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1256 EKQLADSlnrENELEREKRDYDEKINSLY--GQNQKIK-----DEWDDFR---------NDADKE-IQKWKTDAYTVRSE 1318
Cdd:COG4942   89 EKEIAEL---RAELEAQKEELAELLRALYrlGRQPPLAlllspEDFLDAVrrlqylkylAPARREqAEELRADLAELAAL 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529 1319 AKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADtkgnLVQKEMDLESTQNRLR 1390
Cdd:COG4942  166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAE----LQQEAEELEALIARLE 233
46 PHA02562
endonuclease subunit; Provisional
 1121-1380 5.75e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 5.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1121 THTITNTKERIERIEKNILDryhddelVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITE 1200
Cdd:PHA02562  187 DMKIDHIQQQIKTYNKNIEE-------QRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNK 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1201 LKRKHA---AEIDKLKSDISALHDKH-----LSDLDDEKEQYGKavenlksveddLRDKLNNLEKQLADSLNRENELERE 1272
Cdd:PHA02562  260 LNTAAAkikSKIEQFQKVIKMYEKGGvcptcTQQISEGPDRITK-----------IKDKLKELQHSLEKLDTAIDELEEI 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1273 KRDYDEKINSLYGQNQKIKDEwddfrndadkeiqkwKTDAYTVRSEAKALEttntalkaqlqaanDRIDHLTKTVNDHTS 1352
Cdd:PHA02562  329 MDEFNEQSKKLLELKNKISTN---------------KQSLITLVDKAKKVK--------------AAIEELQAEFVDNAE 379

                         250       260
                  ....*....|....*....|....*...
gi 25151529  1353 KVrdltSQVRHLEDELADTKGNLVQKEM 1380
Cdd:PHA02562  380 EL----AKLQDELDKIVKTKSELVKEKY 403
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1162-1307 6.01e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 6.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1162 ELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHA---AEIDKLKSDISALHDKhlsdLDDEKEQYG--- 1235
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEdleKEIKRLELEIEEVEAR----IKKYEEQLGnvr 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529 1236 --KAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQK 1307
Cdd:COG1579   87 nnKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEE 160
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1882-2230 6.11e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.28  E-value: 6.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1882 LETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMK----------DDTDKLRRDLTKAES-VEN 1950
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKsalnelssleDMKNRYESEIKTAESdLSM 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1951 ELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENE---LLNVRSEVRDYkqrvHDVNNRVSELQRQLQDANT 2027
Cdd:PRK01156  268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKkqiLSNIDAEINKY----HAIIKKLSVLQKDYNDYIK 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2028 EKNRVEDrflsVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIE 2107
Cdd:PRK01156  344 KKSRYDD----LNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQ 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2108 LLENEKRRTDAAIRETALQREAIEKSLNAMERENK---------ELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQE 2178
Cdd:PRK01156  420 DISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVcpvcgttlgEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKI 499

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529  2179 RQLIRM--RQEKGQIEKVI--ENRERTHRNRIKQLEDQIAILRDQLDGERRRRREY 2230
Cdd:PRK01156  500 VDLKKRkeYLESEEINKSIneYNKIESARADLEDIKIKINELKDKHDKYEEIKNRY 555
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 715-1036 6.49e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 6.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    715 ARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLEN-------EYNSTQRRIEEKETQIR 787
Cdd:pfam07888   53 ANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAsseelseEKDALLAQRAAHEARIR 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    788 -YSDDIRRNIQK------DLDDLREKYDRVH-------TDNEKILGELEHAQKAAHLAEQQLKEIKiqrdDYQKQKDEHA 853
Cdd:pfam07888  133 eLEEDIKTLTQRvleretELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLSKEFQELR----NSLAQRDTQV 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    854 RHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISDYESQINLLRRhndELDTTIkghqGKITHLENELHSRSGEI 933
Cdd:pfam07888  209 LQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGE---ELSSMA----AQRDRTQAELHQARLQA 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    934 EKLN----DLNQRL-------QKEKQDiLNQKLKLDGD-VQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLS 1001
Cdd:pfam07888  282 AQLTlqlaDASLALregrarwAQERET-LQQSAEADKDrIEKLSAELQRLEERLQEERMEREKLEVELGREKDCNRVQLS 360

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 25151529   1002 RAnllNKELEDTKQDLKHSTDVNKQLEQDIRDLKE 1036
Cdd:pfam07888  361 ES---RRELQELKASLRVAQKEKEQLQAEKQELLE 392
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1124-1532 6.76e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.28  E-value: 6.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1124 ITNTKERIERIEKNIlDRYHDDelveHKIREVNDRWKRELERLENEKDDLERRIRELEDE-------LSQIGRGNDKTEN 1196
Cdd:PRK01156  307 IENKKQILSNIDAEI-NKYHAI----IKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYemdynsyLKSIESLKKKIEE 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1197 DITELKRKHA--AEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNR--------- 1265
Cdd:PRK01156  382 YSKNIERMSAfiSEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgtt 461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1266 --ENELEREKRDYDEKINSLygqNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHL 1343
Cdd:PRK01156  462 lgEEKSNHIINHYNEKKSRL---EEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKI 538

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1344 TKTVNDHTsKVRDLTSQVRHLEDELADTK------GNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGEL--DAALR 1415
Cdd:PRK01156  539 NELKDKHD-KYEEIKNRYKSLKLEDLDSKrtswlnALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFpdDKSYI 617

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1416 ENDILKsnntnMETDLTRLKNRLKSAED---ALKELKNSLSHAKTEKERLQnafrEKTKQADHLNQLASQFDTKLTKLRN 1492
Cdd:PRK01156  618 DKSIRE-----IENEANNLNNKYNEIQEnkiLIEKLRGKIDNYKKQIAEID----SIIPDLKEITSRINDIEDNLKKSRK 688

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 25151529  1493 ELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRK 1532
Cdd:PRK01156  689 ALDDAKANRARLESTIEILRTRINELSDRINDINETLESM 728
PRK11281 PRK11281
mechanosensitive channel MscK;
1732-2137 6.83e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 6.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1732 IANLEGTLQsLLNKIEKLEMERNELRDTlarmkkkttethttinqketryrniednLQDAEEERRALESRLQSAKtllrs 1811
Cdd:PRK11281   62 QQDLEQTLA-LLDKIDRQKEETEQLKQQ----------------------------LAQAPAKLRQAQAELEALK----- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1812 qeealKQRDEERRQMKSKMVAAELQARgkeaqLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRE--- 1888
Cdd:PRK11281  108 -----DDNDEETRETLSTLSLRQLESR-----LAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQirn 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1889 --SDSDTNKYQL---QIASFESERQILTEKI----KELDGALRLSdskvqdmkdDTDKLRRDLTKAEsvenelrktidiQ 1959
Cdd:PRK11281  178 llKGGKVGGKALrpsQRVLLQAEQALLNAQNdlqrKSLEGNTQLQ---------DLLQKQRDYLTAR------------I 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1960 SKTSHEYQLLKDqLLNTQNeLNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSE-LQRQLQDAN--TEKNrvedrf 2036
Cdd:PRK11281  237 QRLEHQLQLLQE-AINSKR-LTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQrLLKATEKLNtlTQQN------ 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2037 LSVEKVVNTMRTTETDL--------------------RQQLETAKNEKRVAtKELEDLkrRLAQLE-NERRNssQLSDGw 2095
Cdd:PRK11281  309 LRVKNWLDRLTQSERNIkeqisvlkgslllsrilyqqQQALPSADLIEGLA-DRIADL--RLEQFEiNQQRD--ALFQP- 382

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 25151529  2096 kKEKITllkkiELLENEKRRTDAAIRETALQ-----REAIE---KSLNAM 2137
Cdd:PRK11281  383 -DAYID-----KLEAGHKSEVTDEVRDALLQllderRELLDqlnKQLNNQ 426
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2002-2221 6.91e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 6.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2002 RDYKQRVHDVNNRVSELQRQLQDANTEKNRV-------EDRFLSvEKVVNTMRTT--ETDLRQQLETAKNEKRVATKELE 2072
Cdd:COG3206  107 EDPLGEEASREAAIERLRKNLTVEPVKGSNVieisytsPDPELA-AAVANALAEAylEQNLELRREEARKALEFLEEQLP 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2073 DLKRRLAQLENER---RNSSQLSDGwKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCA 2149
Cdd:COG3206  186 ELRKELEEAEAALeefRQKNGLVDL-SEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2150 QLQQQIAQLEMENgnRILELTNK----------QREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQ 2219
Cdd:COG3206  265 IQQLRAQLAELEA--ELAELSARytpnhpdviaLRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR 342


                 ..
gi 25151529 2220 LD 2221
Cdd:COG3206  343 LA 344
PTZ00121 PTZ00121
MAEBL; Provisional
 1743-2105 7.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 7.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1743 LNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALEsRLQSAKTLLRSQEEALKQRDEE 1822
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE-ELKKAEEENKIKAAEEAKKAEE 1672

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1823 RRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIAS 1902
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1903 FESERQILTEKIKELDGALRLSDSKVQDMKDDTDKlrRDLTKAESVEnelRKTIDIQSKTSHEYQLLKDQLLNTQNELNG 1982
Cdd:PTZ00121 1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE--EDEKRRMEVD---KKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1983 ANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDrflSVEKVVNTMRTTETDlRQQLETAKN 2062
Cdd:PTZ00121 1828 EDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKED---DEEEIEEADEIEKID-KDDIEREIP 1903

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 25151529  2063 EKRVATKELEDLKRRLAQLENERRNSSQLsdgwKKEKITLLKK 2105
Cdd:PTZ00121 1904 NNNMAGKNNDIIDDKLDKDEYIKRDAEET----REEIIKISKK 1942
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1948-2217 8.02e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 8.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1948 VENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANT 2027
Cdd:COG4372   29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2028 EKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITllKKIE 2107
Cdd:COG4372  109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAE--QALD 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2108 LLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQE 2187
Cdd:COG4372  187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                        250       260       270
                 ....*....|....*....|....*....|
gi 25151529 2188 KGQIEKVIENRERTHRNRIKQLEDQIAILR 2217
Cdd:COG4372  267 ILVEKDTEEEELEIAALELEALEEAALELK 296
Tht1 pfam04163
Tht1-like nuclear fusion protein;
1223-1482 8.04e-04

Tht1-like nuclear fusion protein;


Pssm-ID: 282073  Cd Length: 595  Bit Score: 44.82  E-value: 8.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1223 HLSDLDDEKEQYGKAVENL----KSVEDDLRDKLNNLEKQLA-DSLNRENELEREKRDYDEKINSLYGQNQKI-KDEWDD 1296
Cdd:pfam04163  153 REALLEFEKELIIELFLNItelqDQFGDDLDMKILHLMFQMEqDFENFLDDLAQMFDKFDGEFNNATESNRIIiENDFKD 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1297 FRNDADKEIQKWktdaytvrSEAKALETTNTALKAQLQAANDRIdhltktvndhTSKVRDLTSQVRHLEDELADTKGNLV 1376
Cdd:pfam04163  233 FNFKVNDEIMGL--------VELENHEQEGMVLEKEIIEKIKQL----------KNEIDDIHHFFADFADELAGYKNDII 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1377 QKEMDLESTQnrlrsledQHSTLQSDANKWRGELDAALRENdilksnntnmetdltrLKNRLKSAEDALKE-LKNSLSHA 1455
Cdd:pfam04163  295 EKINDLKDDS--------ENAIALSAIGKYTSEFSAFMEKN----------------IKDLIEMSEDSLKEsVQRNIDFV 350

                          250       260
                   ....*....|....*....|....*..
gi 25151529   1456 KTEKERLQNAFREKTKQADHLNQLASQ 1482
Cdd:pfam04163  351 NSGFQELEDFSIGLKEELGGLKKDLSE 377
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1790-2140 8.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 8.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1790 DAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMvaAELQARGKEAQL---RHLNEQLKNLRTDLDNAHTDIR 1866
Cdd:COG3096  833 DPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQL--QLLNKLLPQANLladETLADRLEELREELDAAQEAQA 910

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1867 SLRDKEEQWDssrfQLETKMRESDSDTNKY-QLQIASFE--SERQILTEKIKELD------GALRLSDS-----KVQDMk 1932
Cdd:COG3096  911 FIQQHGKALA----QLEPLVAVLQSDPEQFeQLQADYLQakEQQRRLKQQIFALSevvqrrPHFSYEDAvgllgENSDL- 985

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1933 ddTDKLRRDLTKAESVENELRKTI-DIQSKTSHEYQLLKDqllntqneLNGANNRKQQLENELLN--------------- 1996
Cdd:COG3096  986 --NEKLRARLEQAEEARREAREQLrQAQAQYSQYNQVLAS--------LKSSRDAKQQTLQELEQeleelgvqadaeaee 1055

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1997 -VRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVntmrtteTDLRQQLETAKN------------- 2062
Cdd:COG3096 1056 rARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDY-------KQEREQVVQAKAgwcavlrlardnd 1128

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2063 -EKRVATKEL-----EDLKR---------RLAQLENER-RNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQ 2126
Cdd:COG3096 1129 vERRLHRRELaylsaDELRSmsdkalgalRLAVADNEHlRDALRLSEDPRRPERKVQFYIAVYQHLRERIRQDIIRTDDP 1208

                        410
                 ....*....|....
gi 25151529 2127 REAIEKslnaMERE 2140
Cdd:COG3096 1209 VEAIEQ----MEIE 1218
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1160-2140 8.70e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 8.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1160 KRELERLENekdDLERRIRELEDELSQIGRGNDKTENDITELKRKHAAEID---KL---KSDISALHDKHLSDLDDEKEQ 1233
Cdd:pfam01576   70 KQELEEILH---ELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAarqKLqleKVTTEAKIKKLEEDILLLEDQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1234 YGKAVENLKSVEddlrDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYG---QNQKIKDEWDDFRNDADKEIQKWKT 1310
Cdd:pfam01576  147 NSKLSKERKLLE----ERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEErlkKEEKGRQELEKAKRKLEGESTDLQE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1311 DAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDeladtkgnlvqkemDLESTQNRLR 1390
Cdd:pfam01576  223 QIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQE--------------DLESERAARN 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1391 SLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRL----KSAEDALKELKNSLSHAKTE-KERLQNA 1465
Cdd:pfam01576  289 KAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALeeetRSHEAQLQEMRQKHTQALEElTEQLEQA 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1466 FR-----EKTKQA------------DHLNQLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQ 1528
Cdd:pfam01576  369 KRnkanlEKAKQAlesenaelqaelRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSL 448

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1529 IQRKSDEYQTTIDDLAhshrvSEDSRLNALQEL--EARKYEINdLTSRLDSTEQRLATLQQdyiKADSERDILSDALRRF 1606
Cdd:pfam01576  449 LNEAEGKNIKLSKDVS-----SLESQLQDTQELlqEETRQKLN-LSTRLRQLEDERNSLQE---QLEEEEEAKRNVERQL 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1607 QSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGGPSA------QRSGAYDPSSGGVIGSGISGGPGGSDFGRE------I 1674
Cdd:pfam01576  520 STLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEAltqqleEKAAAYDKLEKTKNRLQQELDDLLVDLDHQrqlvsnL 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1675 EIGRGDSDQSdVAYPRSVpfppSADFSSGRPGA-ASAGGRVINNLdgtttvnmnggfdiaNLEGTLQSLLNKIEKLEMER 1753
Cdd:pfam01576  600 EKKQKKFDQM-LAEEKAI----SARYAEERDRAeAEAREKETRAL---------------SLARALEEALEAKEELERTN 659

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1754 NELRdtlARMkkkttetHTTINQKEtryrNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAA 1833
Cdd:pfam01576  660 KQLR---AEM-------EDLVSSKD----DVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQAL 725

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1834 ------ELQARGK--EAQLRHLNEQLKNLRTDLDNAhtdirslRDKEEQWDSSRFQLETKMRESDSDTN----------- 1894
Cdd:pfam01576  726 kaqferDLQARDEqgEEKRRQLVKQVRELEAELEDE-------RKQRAQAVAAKKKLELDLKELEAQIDaankgreeavk 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1895 ---KYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAE-----------SVENELRKTIDIQS 1960
Cdd:pfam01576  799 qlkKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASErarrqaqqerdELADEIASGASGKS 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1961 KTSHEYQLLKDQLLNTQNELNGANN---------RKQQLENELLNVR-SEVRDYKQRvhdVNNRVSELQRQLQDANTEKN 2030
Cdd:pfam01576  879 ALQDEKRRLEARIAQLEEELEEEQSntellndrlRKSTLQVEQLTTElAAERSTSQK---SESARQQLERQNKELKAKLQ 955

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2031 RVEDRFLSVEKvvNTMRTTETDLRQ---QLETAKNEKRVATKEL----EDLKRRLAQLENERRNSSQLSDGWKKEKI--- 2100
Cdd:pfam01576  956 EMEGTVKSKFK--SSIAALEAKIAQleeQLEQESRERQAANKLVrrteKKLKEVLLQVEDERRHADQYKDQAEKGNSrmk 1033

                         1050      1060      1070      1080
                   ....*....|....*....|....*....|....*....|..
gi 25151529   2101 TLLKKIELLENEKRRTDAAIREtaLQREAIE--KSLNAMERE 2140
Cdd:pfam01576 1034 QLKRQLEEAEEEASRANAARRK--LQRELDDatESNESMNRE 1073
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1738-2203 9.59e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 9.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1738 TLQSLLNKIEKLEMERNELRDTLARMKKKttethttinqketryrnIEDNLQDAEEERRALESRLQSAKTLLRSQEEALK 1817
Cdd:TIGR00618  404 ILQREQATIDTRTSAFRDLQGQLAHAKKQ-----------------QELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1818 QRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLR-------------TDLDNAHTDIRSLRDKEEQWDSSRFQLET 1884
Cdd:TIGR00618  467 SLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplcgscihpnparQDIDNPGPLTRRMQRGEQTYAQLETSEED 546

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1885 KMRESDSDTNKyqlqiasfeseRQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRdltkaesVENELRKTIDIQSKtsh 1964
Cdd:TIGR00618  547 VYHQLTSERKQ-----------RASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN-------ITVRLQDLTEKLSE--- 605

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1965 eyqlLKDQLLntqnELNGANNRKQQLENELLNVRSEVRDYKQRvhdvnnrvselqrqLQDANTEKNRvedrflsvekvvn 2044
Cdd:TIGR00618  606 ----AEDMLA----CEQHALLRKLQPEQDLQDVRLHLQQCSQE--------------LALKLTALHA------------- 650

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2045 tmrtTETDLRQQLETAKnEKRVATKELEDLKRRLAQLENERRNSSQLSdGWKKE---KITLLKKIELLENEKRR------ 2115
Cdd:TIGR00618  651 ----LQLTLTQERVREH-ALSIRVLPKELLASRQLALQKMQSEKEQLT-YWKEMlaqCQTLLRELETHIEEYDRefneie 724

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2116 --TDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQliRMRQEKGQIEK 2193
Cdd:TIGR00618  725 naSSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN--RLREEDTHLLK 802

                          490
                   ....*....|
gi 25151529   2194 VIENRERTHR 2203
Cdd:TIGR00618  803 TLEAEIGQEI 812
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1263-1608 9.70e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 44.35  E-value: 9.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1263 LNRENELEREKRDYDEKINSLYGQNQKIKDewddfrnDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDR--- 1339
Cdd:pfam05557   12 SQLQNEKKQMELEHKRARIELEKKASALKR-------QLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKkky 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1340 IDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQ---SDANKWRGELDAALRE 1416
Cdd:pfam05557   85 LEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKakaSEAEQLRQNLEKQQSS 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1417 ndiLKSNNTNMETdltrLKNRLKSAEDALKELKNSlshaKTEKERLQNAFREKTKQADHLNQLASQFDTKLTkLRNELQD 1496
Cdd:pfam05557  165 ---LAEAEQRIKE----LEFEIQSQEQDSEIVKNS----KSELARIPELEKELERLREHNKHLNENIENKLL-LKEEVED 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1497 TNDKLITSDTERNALRN---ELQKLSQELKFGNEQIQRKSDEYQTTID-----------DLAHSHRVS---------EDS 1553
Cdd:pfam05557  233 LKRKLEREEKYREEAATlelEKEKLEQELQSWVKLAQDTGLNLRSPEDlsrrieqlqqrEIVLKEENSsltssarqlEKA 312

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 25151529   1554 RLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQS 1608
Cdd:pfam05557  313 RRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDK 367
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1786-2200 9.94e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 9.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1786 DNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQArgKEAQLRHLNEQLKNLRTDLDNAHTDI 1865
Cdd:TIGR00606  393 KNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIEL--KKEILEKKQEELKFVIKELQQLEGSS 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1866 RSLRDKEEQWDSSRFQLEtkMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKA 1945
Cdd:TIGR00606  471 DRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD 548

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1946 ESV-ENELRKTIDIQS----------------KTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRV 2008
Cdd:TIGR00606  549 EQIrKIKSRHSDELTSllgyfpnkkqledwlhSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2009 HDV------NNRVSELQRQLQDANTE------KNRVEDRFL--------SVEKVVNTMRTTETDLRQQLETAKNEKRVAT 2068
Cdd:TIGR00606  629 FDVcgsqdeESDLERLKEEIEKSSKQramlagATAVYSQFItqltdenqSCCPVCQRVFQTEAELQEFISDLQSKLRLAP 708

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2069 KELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNA------------ 2136
Cdd:TIGR00606  709 DKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTimpeeesakvcl 788

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529   2137 -----MERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRER 2200
Cdd:TIGR00606  789 tdvtiMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE 857
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 1121-1570 1.10e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 44.44  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1121 THTITNTKERIERIEKNILDRYHDDELveHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITE 1200
Cdd:PTZ00440 2163 SEAVTNSEEIIENIKKEIIEINENTEM--NTLENTADKLKELYENLKKKKNIINNIYKKINFIKLQEIENSSEKYNDISK 2240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1201 LKRKhaaEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRD----- 1275
Cdd:PTZ00440 2241 LFNN---VVETQKKKLLDNKNKINNIKDKINDKEKELINVDSSFTLESIKTFNEIYDDIKSNIGDLYKLEDTNNDelkkv 2317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1276 --YDEKINSLYGQNQKIKDEWDDFRNDA---DKEIQKWKTDAYTVRSEAKALETTNTALKAQLQaandrIDHLTKTVNDH 1350
Cdd:PTZ00440 2318 klYIENITHLLNRINTLINDLDNYQDENygkDKNIELNNENNSYIIKTKEKINNLKEEFSKLLK-----NIKRNNTLCNN 2392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1351 TSKVRDLTSQVRHLEDELADTKGNLVQKE--MDLESTQNRLRSL---EDQHSTLQSDANKWRGELDAALRENDILKSNNT 1425
Cdd:PTZ00440 2393 NNIKDFISNIGKSVETIKQRFSSNLPEKEklHQIEENLNEIKNImneTKRISNVDAFTNKILQDIDNEKNKENNNMNAEK 2472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1426 --NMETDLTRLKNRLKSAedaLKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLIT 1503
Cdd:PTZ00440 2473 idDLIENVTSHNEKIKSE---LLIINDALRRVKEKKDEMNKLFNSLTENNNNNNNSAKNIVDNSTYIINELESHVSKLNE 2549

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25151529  1504 ----SDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSH-RVSEDSRLNALQELEARKYEIND 1570
Cdd:PTZ00440 2550 llsyIDNEIKELENEKLKLLEKAKIEESRKERERIESETQEDNTDEEQiNRQQQERLQKEEEQKAYSQERLN 2621
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1128-1257 1.11e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1128 KERIERIEKNILDRYHDDELVEHKIREVNDRwKRELERLENEKDDLERRIRELEDELSqigrgndKTENDITELKRKHAA 1207
Cdd:COG2433  388 KELPEEEPEAEREKEHEERELTEEEEEIRRL-EEQVERLEAEVEELEAELEEKDERIE-------RLERELSEARSEERR 459

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 25151529 1208 EIDKlksdisalhDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEK 1257
Cdd:COG2433  460 EIRK---------DREISRLDREIERLERELEEERERIEELKRKLERLKE 500
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 855-991 1.20e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.47  E-value: 1.20e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529     855 HLFDIRHKLETEIKG----RQDLEKNGARNNDELDKLRQTISDYESQINLLRRHNDELDttiKGHQGKITHLENELHSRS 930
Cdd:smart00787  141 LLEGLKEGLDENLEGlkedYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELE---DCDPTELDRAKEKLKKLL 217

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529     931 GEIE----KLNDLNQRLQKEKQDIlnqklkldGDVQALKETIRKLENELEKLRNENKELVGKEAR 991
Cdd:smart00787  218 QEIMikvkKLEELEEELQELESKI--------EDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIE 274
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1735-2221 1.22e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1735 LEGTLqsLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDA--------EEERRALESRLQSAK 1806
Cdd:TIGR02169  223 YEGYE--LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELE 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1807 TLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKM 1886
Cdd:TIGR02169  301 AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1887 RESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQ----SKT 1962
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQewklEQL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1963 SHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHD--------------VNNRVSEL-----QRQLQ 2023
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraveevlkasiqgVHGTVAQLgsvgeRYATA 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2024 DANTEKNR-----VED--------RFLSVEKV-------VNTMRTTETDLR----------------------------- 2054
Cdd:TIGR02169  541 IEVAAGNRlnnvvVEDdavakeaiELLKRRKAgratflpLNKMRDERRDLSilsedgvigfavdlvefdpkyepafkyvf 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2055 ------QQLETAKN----------------------------------------EKRVATKELEDLKRRLAQLENERRNS 2088
Cdd:TIGR02169  621 gdtlvvEDIEAARRlmgkyrmvtlegelfeksgamtggsraprggilfsrsepaELQRLRERLEGLKRELSSLQSELRRI 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2089 SQLSDGWK-------KEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLE-- 2159
Cdd:TIGR02169  701 ENRLDELSqelsdasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEea 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2160 ------MENGNRILELTNKQRE-------------EQERQLIRMRQEKGQIEKVIENRErthrNRIKQLEDQIAILRDQL 2220
Cdd:TIGR02169  781 lndleaRLSHSRIPEIQAELSKleeevsriearlrEIEQKLNRLTLEKEYLEKEIQELQ----EQRIDLKEQIKSIEKEI 856


                   .
gi 25151529   2221 D 2221
Cdd:TIGR02169  857 E 857
PRK09039 PRK09039
peptidoglycan -binding protein;
935-1041 1.26e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   935 KLNDLNQRLQKEKQdilnQKLKLDGDVQALKETIRKLENELEKLRNENKELvgkeARARDAANQqlsRANLLNKELEDTK 1014
Cdd:PRK09039   61 QIAELADLLSLERQ----GNQDLQDSVANLRASLSAAEAERSRLQALLAEL----AGAGAAAEG---RAGELAQELDSEK 129

                          90       100       110
                  ....*....|....*....|....*....|.
gi 25151529  1015 Q----DLKHSTDVNKQLEQdirdLKERLANI 1041
Cdd:PRK09039  130 QvsarALAQVELLNQQIAA----LRRQLAAL 156
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1810-2131 1.27e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1810 RSQEEALKQRDEERRQMKSKMVAAELQARgkeaqlRHLNEQLKNLRTDLDNAHTdIRSLRDK---EEQWDSSRFQLETKM 1886
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEEKAREVERR------RKLEEAEKARQAEMDRQAA-IYAEQERmamERERELERIRQEERK 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1887 RESDsdtnkyqlQIASFESERQIltEKIKELDgalRLSDSKVQdmkdDTDKLRRDLTKAESVE-NELRKTIDIQSKTSHE 1965
Cdd:pfam17380  360 RELE--------RIRQEEIAMEI--SRMRELE---RLQMERQQ----KNERVRQELEAARKVKiLEEERQRKIQQQKVEM 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1966 YQLLKDQLLNTQNELngaNNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKnrvEDRFLSVEKVVNT 2045
Cdd:pfam17380  423 EQIRAEQEEARQREV---RRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEK---RDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2046 MRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQ------LENERRNSSQLsdgwkKEKITLLKKIELLENEKRRTDAA 2119
Cdd:pfam17380  497 LEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEeerrreAEEERRKQQEM-----EERRRIQEQMRKATEERSRLEAM 571

                          330
                   ....*....|..
gi 25151529   2120 IRETALQREAIE 2131
Cdd:pfam17380  572 EREREMMRQIVE 583
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2067-2219 1.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2067 ATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKEL-- 2144
Cdd:COG4942   18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELra 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2145 ----------------YKNCAQLQQQ-----IAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHR 2203
Cdd:COG4942   98 eleaqkeelaellralYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                        170
                 ....*....|....*.
gi 25151529 2204 NRIKQLEDQIAILRDQ 2219
Cdd:COG4942  178 ALLAELEEERAALEAL 193
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 742-1405 1.41e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    742 RRVENLLRENNRLKSEVNPLKDkyrdLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDD-LREKYDRVHTDNEKILGE 820
Cdd:pfam12128  234 AGIMKIRPEFTKLQQEFNTLES----AELRLSHLHFGYKSDETLIASRQEERQETSAELNQlLRTLDDQWKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    821 LEHAQKAAHLAEQQLKEIKIQRDDYQKQKDE----HARHLFDIRHKLETEIKGRQDLEKNGARNNDELDKLRQTISdyES 896
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLDADIEtaaaDQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK--EQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    897 QINLLRRHNDELD----TTIKGH---QGKITHLENEL-HSRSGEIEKLNDLNQRLqkeKQDILNQKLKLDgDVQALKETI 968
Cdd:pfam12128  388 NNRDIAGIKDKLAkireARDRQLavaEDDLQALESELrEQLEAGKLEFNEEEYRL---KSRLGELKLRLN-QATATPELL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    969 RKLEN----------ELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKH--------STDVNKQLEQD 1030
Cdd:pfam12128  464 LQLENfderierareEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDElelqlfpqAGTLLHFLRKE 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1031 IRDLKErlaNIGKggRISRDSTTGTDGGAFGDRSSVADPSRTRGaagstvfvpAAEDIEsrgggEIDIPSSGDviHGRDG 1110
Cdd:pfam12128  544 APDWEQ---SIGK--VISPELLHRTDLDPEVWDGSVGGELNLYG---------VKLDLK-----RIDVPEWAA--SEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1111 RDGRDAGNRgthTITNTKERIERIEKnildryhddELVEhkIREVNDRWKRELER----LENEKDDLERRIRELEDELSQ 1186
Cdd:pfam12128  603 RERLDKAEE---ALQSAREKQAAAEE---------QLVQ--ANGELEKASREETFartaLKNARLDLRRLFDEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1187 IGRGNDKTENDITELKRKHAAEIDKLKSDISAL---HDKHLSDLDDEKEQYGKAVENLKSVEDDLRD------------K 1251
Cdd:pfam12128  669 KNKALAERKDSANERLNSLEAQLKQLDKKHQAWleeQKEQKREARTEKQAYWQVVEGALDAQLALLKaaiaarrsgakaE 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1252 LNNLEKQLADSL-------NRENELEREKRDYDEKINSLYGQNQKIKdEWDDFRNDA-DKEIQKWKTDAYTVRSEAKALE 1323
Cdd:pfam12128  749 LKALETWYKRDLaslgvdpDVIAKLKREIRTLERKIERIAVRRQEVL-RYFDWYQETwLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1324 TTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTK--GNLVQKEMDLESTQNRLRSLEDQHSTLQS 1401
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKedANSEQAQGSIGERLAQLEDLKLKRDYLSE 907


                   ....
gi 25151529   1402 DANK 1405
Cdd:pfam12128  908 SVKK 911
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
492-857 1.44e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  492 ADLLEELRKIRGGGSSEGDAELhKELMTKYEESIERNIELESRGDDSQRKIAELEAELRRNREKLnEAQGALKKLHEMAQ 571
Cdd:COG4717  173 AELQEELEELLEQLSLATEEEL-QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL-EAAALEERLKEARL 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  572 DSekNVDGTVSIKRTRSLSPGKTPLPPSEALRAVRNTFRNkdnDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQF 651
Cdd:COG4717  251 LL--LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAL---LFLLLAREKASLGKEAEELQALPALEELEEEELEELL 325

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  652 ADAKREISNLQKSVDEAERNSRRTDDKLRasEAERVAAEKARKFLEDELAKLQASFQKSSTDD----------ARKLRDE 721
Cdd:COG4717  326 AALGLPPDLSPEELLELLDRIEELQELLR--EAEELEEELQLEELEQEIAALLAEAGVEDEEElraaleqaeeYQELKEE 403

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  722 MDEHTNSIQEEFKTRIDELNRRV-ENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDdirrnIQKDL 800
Cdd:COG4717  404 LEELEEQLEELLGELEELLEALDeEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE-----LLQEL 478

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  801 DDLREKydrvhtdnekiLGELEHAQKAAHLAEQQLKE-IKIQRDDYQKQKDEHARHLF 857
Cdd:COG4717  479 EELKAE-----------LRELAEEWAALKLALELLEEaREEYREERLPPVLERASEYF 525
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1124-1255 1.53e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1124 ITNTKERIERIEKNILDRYHDDELVEHKIREVNDRWK------------RELERLENEKDDLERRIRELEDELSQIGRGN 1191
Cdd:COG1579   47 LEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvrnnkeyealqKEIESLKRRISDLEDEILELMERIEELEEEL 126

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25151529 1192 DKTENDITELKRKHAAEIDKLKSDISALhDKHLSDLDDEKEQYGKAV-ENLKSVEDDLRDKLNNL 1255
Cdd:COG1579  127 AELEAELAELEAELEEKKAELDEELAEL-EAELEELEAEREELAAKIpPELLALYERIRKRKNGL 190
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1747-2084 1.55e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1747 EKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQM 1826
Cdd:COG4372    6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1827 KSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESE 1906
Cdd:COG4372   86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1907 RQILTE-----KIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELN 1981
Cdd:COG4372  166 LAALEQelqalSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELE 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1982 GANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAK 2061
Cdd:COG4372  246 EDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELA 325

                        330       340
                 ....*....|....*....|...
gi 25151529 2062 NEKRVATKELEDLKRRLAQLENE 2084
Cdd:COG4372  326 KKLELALAILLAELADLLQLLLV 348
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1947-2086 1.56e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1947 SVENELRKTIDIQSKTSHEYQL------LKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQR 2020
Cdd:COG1579    1 AMPEDLRALLDLQELDSELDRLehrlkeLPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529 2021 QLQDANTEK--NRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERR 2086
Cdd:COG1579   81 QLGNVRNNKeyEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD 148
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1237-1568 1.60e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.98  E-value: 1.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1237 AVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTdaytvr 1316
Cdd:COG1340    2 KTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKE------ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1317 seakalettntaLKAQLQAANDRIDHLTKTVndhtskvrdltsqvrhleDELADTKGNLVQKEMDLESTQNRLRSLEDQH 1396
Cdd:COG1340   76 ------------LKEERDELNEKLNELREEL------------------DELRKELAELNKAGGSIDKLRKEIERLEWRQ 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1397 STLQSDANKwrgeldaalrENDILKsnntnmetDLTRLKNRLKSAEDALkELKNSLSHAKTEKERLQNAFREKTKQADHL 1476
Cdd:COG1340  126 QTEVLSPEE----------EKELVE--------KIKELEKELEKAKKAL-EKNEKLKELRAELKELRKEAEEIHKKIKEL 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1477 NQLASQFDTKLTKLRNELQDTNDklitsdtERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDL-AHSHRVSEDSRL 1555
Cdd:COG1340  187 AEEAQELHEEMIELYKEADELRK-------EADELHKEIVEAQEKADELHEEIIELQKELRELRKELkKLRKKQRALKRE 259

                        330
                 ....*....|...
gi 25151529 1556 NALQELEARKYEI 1568
Cdd:COG1340  260 KEKEELEEKAEEI 272
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 873-1036 2.00e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 43.30  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    873 LEKNGARNNDELDKLRQTISDYESQINLLrrhnDELDTTIKGHQGKITHlENELHSrsgeiEKLNDLNQRLQKEKQDI-- 950
Cdd:pfam09726  400 LEQDIKKLKAELQASRQTEQELRSQISSL----TSLERSLKSELGQLRQ-ENDLLQ-----TKLHNAVSAKQKDKQTVqq 469

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    951 LNQKLKLDGDVQALKEtirKLENElEKLRNENKELVGKEARARDAANQQ------LSRANLLNKELEDTKQDLKHSTDVN 1024
Cdd:pfam09726  470 LEKRLKAEQEARASAE---KQLAE-EKKRKKEEEATAARAVALAAASRGecteslKQRKRELESEIKKLTHDIKLKEEQI 545

                          170
                   ....*....|....*
gi 25151529   1025 KQLE---QDIRDLKE 1036
Cdd:pfam09726  546 RELEikvQELRKYKE 560
46 PHA02562
endonuclease subunit; Provisional
 1322-1544 2.03e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1322 LETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTkgnlvqkEMDLESTQNRLRSLEDQHSTLQS 1401
Cdd:PHA02562  197 IKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNL-------VMDIEDPSAALNKLNTAAAKIKS 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1402 DANKWRGELDAaLRENDILKsnnTNMETdltrlknrLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLAs 1481
Cdd:PHA02562  270 KIEQFQKVIKM-YEKGGVCP---TCTQQ--------ISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS- 336

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529  1482 qfdTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLA 1544
Cdd:PHA02562  337 ---KKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKS 396
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1161-1568 2.03e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 43.30  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1161 RELERLENEKDDLERriRELEDELSQIGRGN---------DKTENDITELKRKHAAEIDKLKSDISALHDKHlsdlddek 1231
Cdd:pfam06160   10 KEIDELEERKNELMN--LPVQEELSKVKKLNltgetqekfEEWRKKWDDIVTKSLPDIEELLFEAEELNDKY-------- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1232 eQYGKAvenlKSVEDDLRDKLNNLEKQLADSLNRENELeREKrdydEKINSLygQNQKIKDEWDDFRN----------DA 1301
Cdd:pfam06160   80 -RFKKA----KKALDEIEELLDDIEEDIKQILEELDEL-LES----EEKNRE--EVEELKDKYRELRKtllanrfsygPA 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1302 DKEIQKWKTDAYTVRSEAKALETTNTALKA--QLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKE 1379
Cdd:pfam06160  148 IDELEKQLAEIEEEFSQFEELTESGDYLEAreVLEKLEEETDALEELMEDIPPLYEELKTELPDQLEELKEGYREMEEEG 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1380 MDLESTQ--NRLRSLEDQHSTLQSDANKwrGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKT 1457
Cdd:pfam06160  228 YALEHLNvdKEIQQLEEQLEENLALLEN--LELDEAEEALEEIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYLEHAEE 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1458 EKERLQNAFREkTKQADHLN----QLASQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELkfgnEQIQRKS 1533
Cdd:pfam06160  306 QNKELKEELER-VQQSYTLNenelERVRGLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQL----EEIEEEQ 380

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 25151529   1534 DEYQTTIDDLahshRVSEDSRLNALQELEARKYEI 1568
Cdd:pfam06160  381 EEFKESLQSL----RKDELEAREKLDEFKLELREI 411
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
530-799 2.15e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.59  E-value: 2.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  530 ELESRGDDSQRKIAELEAELRRNREKLNEAQGALKKLHEmaQDSEKNvdgtvsiKRTRSLspgktplppSEALRAVRNTF 609
Cdd:COG1340    5 ELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAE--KRDELN-------AQVKEL---------REEAQELREKR 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  610 RNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKqfadAKREISNLQKSVDEAER----------NSRRTDDKL 679
Cdd:COG1340   67 DELNEKVKELKEERDELNEKLNELREELDELRKELAELNK----AGGSIDKLRKEIERLEWrqqtevlspeEEKELVEKI 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  680 RASEAERVAAEKARKfLEDELAKLQASFQKSStDDARKLRDEMDEHTNSIQeEFKTRIDELNRRVENLLRENNRLKSEVN 759
Cdd:COG1340  143 KELEKELEKAKKALE-KNEKLKELRAELKELR-KEAEEIHKKIKELAEEAQ-ELHEEMIELYKEADELRKEADELHKEIV 219

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 25151529  760 PLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIRRNIQKD 799
Cdd:COG1340  220 EAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKRE 259
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 883-1044 2.29e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 2.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  883 ELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKlkldgDVQ 962
Cdd:COG1579   18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNK-----EYE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  963 ALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELEDTKQDLKhstDVNKQLEQDIRDLKERLANIG 1042
Cdd:COG1579   93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD---EELAELEAELEELEAEREELA 169


                 ..
gi 25151529 1043 KG 1044
Cdd:COG1579  170 AK 171
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1166-1283 2.54e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1166 LENEKDDLERRIRELE----DELSQIGrGNDKTEN---DITELKRKhaaeIDKLKSDISALHDKhlsdlddEKEQYGKAV 1238
Cdd:PRK05771   14 LKSYKDEVLEALHELGvvhiEDLKEEL-SNERLRKlrsLLTKLSEA----LDKLRSYLPKLNPL-------REEKKKVSV 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 25151529  1239 ENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSL 1283
Cdd:PRK05771   82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1166-1308 2.61e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.31  E-value: 2.61e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    1166 LENEKDDLERRIRELEDELSQIgrgndktenditelkRKHAAEIDKLKSDISALHDKHLSDLDDEKEQyGKAVENLKSVE 1245
Cdd:smart00787  142 LEGLKEGLDENLEGLKEDYKLL---------------MKELELLNSIKPKLRDRKDALEEELRQLKQL-EDELEDCDPTE 205

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529    1246 DD-LRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDAdKEIQKW 1308
Cdd:smart00787  206 LDrAKEKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKL-EQCRGF 268
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1160-1543 2.62e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.90  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1160 KRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHaaeiDKLKSDISA----------LHDKHLSDLDD 1229
Cdd:PRK04778  104 KHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLY----RELRKSLLAnrfsfgpaldELEKQLENLEE 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1230 EKEQYGKAVEN-----LKSVEDDLRDKLNNLEKQLADSLNRENELEREkrdYDEKINSL-YGQNQKIKDEWDDFRNDADK 1303
Cdd:PRK04778  180 EFSQFVELTESgdyveAREILDQLEEELAALEQIMEEIPELLKELQTE---LPDQLQELkAGYRELVEEGYHLDHLDIEK 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1304 EIQKWKTDAYTVRSEAKALETTNTalKAQLQAANDRIDHLTKTV-------NDHTSKVRDLTSQVRHLEDELADTKGNL- 1375
Cdd:PRK04778  257 EIQDLKEQIDENLALLEELDLDEA--EEKNEEIQERIDQLYDILerevkarKYVEKNSDTLPDFLEHAKEQNKELKEEId 334

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1376 -VQK-----EMDLESTqnrlRSLEDQHSTLQSDANkwrgELDAALRENDILKSnntnmetdltrlknrlkSAEDALKELK 1449
Cdd:PRK04778  335 rVKQsytlnESELESV----RQLEKQLESLEKQYD----EITERIAEQEIAYS-----------------ELQEELEEIL 389

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1450 NSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTN---------DKLITSDTERNALRNELqklsQ 1520
Cdd:PRK04778  390 KQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNKLHEIKRYLEKSNlpglpedylEMFFEVSDEIEALAEEL----E 465

                         410       420
                  ....*....|....*....|...
gi 25151529  1521 ELKFGNEQIQRKSDEYQTTIDDL 1543
Cdd:PRK04778  466 EKPINMEAVNRLLEEATEDVETL 488
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1214-1391 2.65e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1214 SDISALHDkhLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKInslygqnqkikde 1293
Cdd:COG1579    4 EDLRALLD--LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI------------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1294 wddfrNDADKEIQKWKTDAYTVRS--EAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADT 1371
Cdd:COG1579   69 -----EEVEARIKKYEEQLGNVRNnkEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEK 143

                        170       180
                 ....*....|....*....|
gi 25151529 1372 KGNLVQKEMDLESTQNRLRS 1391
Cdd:COG1579  144 KAELDEELAELEAELEELEA 163
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1146-1386 2.73e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 42.21  E-value: 2.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1146 ELVEH--KIREVNDRWKRELERLENEKDDLERRIRELEDELSQIgrgndKTENDITELKRKhaaEIDKLKSDISALHDKH 1223
Cdd:COG1340   54 ELREEaqELREKRDELNEKVKELKEERDELNEKLNELREELDEL-----RKELAELNKAGG---SIDKLRKEIERLEWRQ 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1224 L-SDLDDEKEQygKAVENLKSVEDDL--RDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRND 1300
Cdd:COG1340  126 QtEVLSPEEEK--ELVEKIKELEKELekAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1301 ADKeiqkwktdaytVRSEAKalettntALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEM 1380
Cdd:COG1340  204 ADE-----------LRKEAD-------ELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265


                 ....*.
gi 25151529 1381 DLESTQ 1386
Cdd:COG1340  266 EEKAEE 271
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1925-2222 2.84e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 2.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1925 DSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDY 2004
Cdd:PRK03918  192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2005 KQRVHDVNNRV-------------SELQRQLQDANTEKNRVEDRFLSVEKVVNTMRttetDLRQQLETAKNEKRVATKEL 2071
Cdd:PRK03918  272 KKEIEELEEKVkelkelkekaeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIE----ERIKELEEKEERLEELKKKL 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2072 EDLKRRLAQLE-------------NERRNSSQLSDGWKKEKITllKKIELLENEKRRTDAAIREtalqreaIEKSLNAME 2138
Cdd:PRK03918  348 KELEKRLEELEerhelyeeakakkEELERLKKRLTGLTPEKLE--KELEELEKAKEEIEEEISK-------ITARIGELK 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2139 RENKELYKN-------------CAQLQQQIAQLE-MENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRN 2204
Cdd:PRK03918  419 KEIKELKKAieelkkakgkcpvCGRELTEEHRKElLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         330
                  ....*....|....*...
gi 25151529  2205 RikQLEDQIAILRDQLDG 2222
Cdd:PRK03918  499 K--ELAEQLKELEEKLKK 514
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1228-1465 2.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1228 DDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQk 1307
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1308 wktDAYTVRSEAKALETTntaLKAQ-LQAANDRIDhLTKTVNDHTskvRDLTSQVRHLEDELADTKGNLVQKEMDLESTQ 1386
Cdd:COG3883   94 ---ALYRSGGSVSYLDVL---LGSEsFSDFLDRLS-ALSKIADAD---ADLLEELKADKAELEAKKAELEAKLAELEALK 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529 1387 NRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNA 1465
Cdd:COG3883  164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1151-1597 2.93e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1151 KIREVNDRWKRELERLENEK--------------DDLERRIRELEDELSQIGRGND---KTENDITELKRKHAAEIDKLK 1213
Cdd:pfam01576  265 KIRELEAQISELQEDLESERaarnkaekqrrdlgEELEALKTELEDTLDTTAAQQElrsKREQEVTELKKALEEETRSHE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1214 SDISALHDKHLSDLDDEKEQygkaVENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIK-- 1291
Cdd:pfam01576  345 AQLQEMRQKHTQALEELTEQ----LEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQar 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1292 -DEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDE--- 1367
Cdd:pfam01576  421 lSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDErns 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1368 -------------------------LADTKGNLVQKEM--------------DLESTQNRLRSLEDQHSTLQSDANKWRG 1408
Cdd:pfam01576  501 lqeqleeeeeakrnverqlstlqaqLSDMKKKLEEDAGtlealeegkkrlqrELEALTQQLEEKAAAYDKLEKTKNRLQQ 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1409 ELDAALRENDILKSNNTNMEtdltrlkNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKtkqadhlnqlasqfDTKLT 1488
Cdd:pfam01576  581 ELDDLLVDLDHQRQLVSNLE-------KKQKKFDQMLAEEKAISARYAEERDRAEAEAREK--------------ETRAL 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1489 KLRNELQDTNDKLITSDTERNALRNELQKL----------SQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNAL 1558
Cdd:pfam01576  640 SLARALEEALEAKEELERTNKQLRAEMEDLvsskddvgknVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE 719

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 25151529   1559 QELEARKYEIN-DLTSRLDSTEQRLATLQQDYIKADSERD 1597
Cdd:pfam01576  720 VNMQALKAQFErDLQARDEQGEEKRRQLVKQVRELEAELE 759
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1178-1482 2.94e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.12  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1178 RELEDELSQIGrgNDKTENDitelkrkhAAEIDKLKSDISALHDKHLSDldDEKEQYGKAVENLKSVEDDLRDKLNNLE- 1256
Cdd:PRK10929   26 KQITQELEQAK--AAKTPAQ--------AEIVEALQSALNWLEERKGSL--ERAKQYQQVIDNFPKLSAELRQQLNNERd 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1257 --KQLADSLNrENELEREKRdydeKINS-LYGQNQKIKDEWDDFRNDADK--EIQKWKTDAYTVRSEA----KALETTNT 1327
Cdd:PRK10929   94 epRSVPPNMS-TDALEQEIL----QVSSqLLEKSRQAQQEQDRAREISDSlsQLPQQQTEARRQLNEIerrlQTLGTPNT 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1328 AL-KAQLQAandridhLTKTVNDHTSKVRDLtsqvrhledELADTKGNLVQK--EMDLESTQNRLRSLEDQHSTLQSDAN 1404
Cdd:PRK10929  169 PLaQAQLTA-------LQAESAALKALVDEL---------ELAQLSANNRQElaRLRSELAKKRSQQLDAYLQALRNQLN 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1405 KWRG-ELDAALRENDILKSNNTNMETDLTRL--KNRlksaedalkELKNSLSHaktekerlqnafrektkQADHLNQLAS 1481
Cdd:PRK10929  233 SQRQrEAERALESTELLAEQSGDLPKSIVAQfkINR---------ELSQALNQ-----------------QAQRMDLIAS 286


                  .
gi 25151529  1482 Q 1482
Cdd:PRK10929  287 Q 287
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 525-914 2.98e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 42.74  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    525 IERNIELESR-------GDDS---QRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTRslspgKT 594
Cdd:pfam13166   71 VEENLSEQGEikpiftlGEESieiQEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKIKR-----KK 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    595 PLPPSEALRAVRNTFRNKDNDIQQLERKLKIAESQVKEflnkfenaDEARRRLDKQFADAKREISNLQKSV---DEAERN 671
Cdd:pfam13166  146 NSALSEALNGFKYEANFKSRLLREIEKDNFNAGVLLSD--------EDRKAALATVFSDNKPEIAPLTFNVidfDALEKA 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    672 SRRTDDKLRASEA-ERVAAE-KARKFLEDELAKLQAS-----FQKSSTDDARKLR------DEMDEHTNSIQEefktRID 738
Cdd:pfam13166  218 EILIQKVIGKSSAiEELIKNpDLADWVEQGLELHKAHldtcpFCGQPLPAERKAAleahfdDEFTEFQNRLQK----LIE 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    739 ELNRRVENLL----------RENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKetqirySDDIRRNIQkdLDDLREKYD 808
Cdd:pfam13166  294 KVESAISSLLaqlpavsdlaSLLSAFELDVEDIESEAEVLNSQLDGLRRALEAK------RKDPFKSIE--LDSVDAKIE 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    809 RVhTDNEKILGEL--EHAQKAAHLAEQQLKEIKIQRDDYQKQKDEHARHLFDIRHKLETEIKgrqDLEKNGARNNDELDK 886
Cdd:pfam13166  366 SI-NDLVASINELiaKHNEITDNFEEEKNKAKKKLRLHLVEEFKSEIDEYKDKYAGLEKAIN---SLEKEIKNLEAEIKK 441

                          410       420
                   ....*....|....*....|....*...
gi 25151529    887 LRQTISDYESQINLLRRHNDELDTTIKG 914
Cdd:pfam13166  442 LREEIKELEAQLRDHKPGADEINKLLKA 469
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1730-2035 3.01e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 3.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1730 FDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLL 1809
Cdd:COG4372   38 FELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEEL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1810 RSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLETKMRES 1889
Cdd:COG4372  118 EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAE 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1890 DSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKvqdmKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLL 1969
Cdd:COG4372  198 KEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLAL----SALLDALELEEDKEELLEEVILKEIEELELAILVEKDT 273

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25151529 1970 KDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDR 2035
Cdd:COG4372  274 EEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAEL 339
PRK12704 PRK12704
phosphodiesterase; Provisional
 609-706 3.11e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 3.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   609 FRNKDNDIQQLERKLKIAESQVKeflNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLraseaERVA 688
Cdd:PRK12704   77 LRERRNELQKLEKRLLQKEENLD---RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL-----ERIS 148

                          90       100
                  ....*....|....*....|....
gi 25151529   689 ---AEKARKFLEDEL---AKLQAS 706
Cdd:PRK12704  149 gltAEEAKEILLEKVeeeARHEAA 172
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1301-1647 3.12e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 3.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1301 ADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKtvndhtsKVRDLTSQVRHLEDELADTKGNLVQKEM 1380
Cdd:COG3883   14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQA-------ELEALQAEIDKLQAEIAEAEAEIEERRE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1381 DLEstqNRLRSLEDQHSTLqsdankwrGELDAALrendilksNNTNMETDLTRLkNRLKSAEDALKELKNSLSHAKTEKE 1460
Cdd:COG3883   87 ELG---ERARALYRSGGSV--------SYLDVLL--------GSESFSDFLDRL-SALSKIADADADLLEELKADKAELE 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1461 RLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLitsDTERNALRNELQKLSQELkfgnEQIQRKSDEYQTTI 1540
Cdd:COG3883  147 AKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQL---SAEEAAAEAQLAELEAEL----AAAEAAAAAAAAAA 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1541 DDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTFV 1620
Cdd:COG3883  220 AAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAA 299

                        330       340
                 ....*....|....*....|....*..
gi 25151529 1621 DGGAGYVDGVPGGTSVIGGGPSAQRSG 1647
Cdd:COG3883  300 SGGSGGGSGGAGGVGSGGGAGAVVGGA 326
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1331-1573 3.29e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1331 AQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGEL 1410
Cdd:COG4372   38 FELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEEL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1411 DAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAfREKTKQADHLNQLASQFDTKLTKL 1490
Cdd:COG4372  118 EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQE-LQALSEAEAEQALDELLKEANRNA 196

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1491 RNELQDTNDKLITSDTERNALRNELQKLSQELKFGNEQIQRKSDEYQTTIDDLAHSHRVSEDSRLNALQELEARKYEIND 1570
Cdd:COG4372  197 EKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEE 276


                 ...
gi 25151529 1571 LTS 1573
Cdd:COG4372  277 ELE 279
Rabaptin pfam03528
Rabaptin;
1245-1609 3.32e-03

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 42.40  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1245 EDDLRDKLNNLEKQLADSLNRENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALET 1324
Cdd:pfam03528    3 DEDLQQRVAELEKENAEFYRLKQQLEAEFNQKRAKFKELYLAKEEDLKRQNAVLQEAQVELDALQNQLALARAEMENIKA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1325 TNTALKAQLQAANDRI-----DHLTKTVNDHTSKVRDLTSQVRH-LEDELAdtKGNLVQKEMDLESTQNRLRSLEDQHS- 1397
Cdd:pfam03528   83 VATVSENTKQEAIDEVksqwqEEVASLQAIMKETVREYEVQFHRrLEQERA--QWNQYRESAEREIADLRRRLSEGQEEe 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1398 TLQSDANKwrgeldaALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNS----LSHA------------------ 1455
Cdd:pfam03528  161 NLEDEMKK-------AQEDAEKLRSVVMPMEKEIAALKAKLTEAEDKIKELEASkmkeLNHYleaekscrtdlemyvavl 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1456 KTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITS------DTER--NALRNELQKLSQELKFGN- 1526
Cdd:pfam03528  234 NTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESqrllmrDMQRmeSVLTSEQLRQVEEIKKKDq 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1527 --EQIQRKSDEYQTTIDDLAHSHRVSEDSRLNALQElearKYEINDLTSRLDSTEQRLATLQQDYIKADS-----ERDIL 1599
Cdd:pfam03528  314 eeHKRARTHKEKETLKSDREHTVSIHAVFSPAGVET----SAPLSNVEEQINSAHGSVHSLDTDVVLGAGdsfnkQEDPF 389

                          410
                   ....*....|
gi 25151529   1600 SDALRRFQSS 1609
Cdd:pfam03528  390 KEGLRRAQST 399
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 616-824 3.39e-03

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 41.55  E-value: 3.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    616 IQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREISNLQKSVDEAERNSRRTDDKLraSEAERVA--AEKAR 693
Cdd:pfam00261    3 MQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKL--EEAEKAAdeSERGR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    694 KFLEDELAKLQAS--FQKSSTDDARKLRDEMDEHTNSIQEEFKT------RIDELNRRVENLLRE-NNRLKSEVNPLK-- 762
Cdd:pfam00261   81 KVLENRALKDEEKmeILEAQLKEAKEIAEEADRKYEEVARKLVVvegdleRAEERAELAESKIVElEEELKVVGNNLKsl 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    763 ----DKYRDLENEYNSTQRRIEE--KETQIRYSDDIRR--NIQKDLDDLREKYDRVHTDNEKILGELEHA 824
Cdd:pfam00261  161 easeEKASEREDKYEEQIRFLTEklKEAETRAEFAERSvqKLEKEVDRLEDELEAEKEKYKAISEELDQT 230
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1831-2094 3.49e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1831 VAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTDIRSLrdkEEQWDSSRFQLETKMRESDsdtnKYQLQIASFESERQIL 1910
Cdd:COG3883   12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEEL---NEEYNELQAELEALQAEID----KLQAEIAEAEAEIEER 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1911 TEKIKEldgalRLSDSKVQDmkDDTDKLRRdLTKAESVENELRKTIDIQSKTSHEYQLLkDQLLNTQNELngaNNRKQQL 1990
Cdd:COG3883   85 REELGE-----RARALYRSG--GSVSYLDV-LLGSESFSDFLDRLSALSKIADADADLL-EELKADKAEL---EAKKAEL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1991 ENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKE 2070
Cdd:COG3883  153 EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232

                        250       260
                 ....*....|....*....|....
gi 25151529 2071 LEDLKRRLAQLENERRNSSQLSDG 2094
Cdd:COG3883  233 AAAAAAAAAAAASAAGAGAAGAAG 256
PRK01156 PRK01156
chromosome segregation protein; Provisional
 319-817 3.60e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.58  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   319 NANYEMIARLDEERRRSDEYRMQWENERQKSLSLEDENDRLR-----------REFERYANDSKDKEKTFINRERNLAQY 387
Cdd:PRK01156  245 SSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIIndpvyknrnyiNDYFKYKNDIENKKQILSNIDAEINKY 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   388 lSDEQRKMLDL---WTELQRVRKQFSDLKtHTEEDLDKQKAEFTRAIRNVNNIsrnaafsagagdglglygledggdvNR 464
Cdd:PRK01156  325 -HAIIKKLSVLqkdYNDYIKKKSRYDDLN-NQILELEGYEMDYNSYLKSIESL-------------------------KK 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   465 TTNNYEKVFIETIKRMNGTGGAGSASSADLLEELRKIRGG----GSSEGDAELHKELMTKYEESIERNIE-LESRG---- 535
Cdd:PRK01156  378 KIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKlqdiSSKVSSLNQRIRALRENLDELSRNMEmLNGQSvcpv 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   536 -------DDSQRKIAELEAELRRNREKLNEAQGALKKLHEMAQDSEKNVDGTVSIKRTRSLspgktplppsealravrnT 608
Cdd:PRK01156  458 cgttlgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSI------------------N 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   609 FRNKDNDIQQLERKLKIAESQVKEFLNKFENADEARRRLDKQFADAKREI---SNLQKSVDEAERNSRRTDDKlraseae 685
Cdd:PRK01156  520 EYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSwlnALAVISLIDIETNRSRSNEI------- 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   686 rvaaEKARKFLEDELAKLQASFQ--KSSTDDA-RKLRDEMDEHTNSIQE--EFKTRIDELNRRVENLLRENNRLKSevnp 760
Cdd:PRK01156  593 ----KKQLNDLESRLQEIEIGFPddKSYIDKSiREIENEANNLNNKYNEiqENKILIEKLRGKIDNYKKQIAEIDS---- 664

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529   761 lkdkyrdLENEYNSTQRRIEEKETQIRYSDDIRRNIQKDLDDLREKYDRVHTDNEKI 817
Cdd:PRK01156  665 -------IIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINEL 714
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1123-1611 4.13e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1123 TITNTKERIERIEKNILDRYHDDELVEHKIR------EVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTEn 1196
Cdd:TIGR00618  216 TYHERKQVLEKELKHLREALQQTQQSHAYLTqkreaqEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAP- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1197 diTELKRKHAAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDlRDKLNNLEKQlADSLNRENELEREKRDY 1276
Cdd:TIGR00618  295 --LAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ-RRLLQTLHSQ-EIHIRDAHEVATSIREI 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1277 DEKINSL---YGQNQKIKDEWDDFRNDADKEIQKWKTDAYTV---RSEAKALETTNTALKAQLQAANDRID----HLTKT 1346
Cdd:TIGR00618  371 SCQQHTLtqhIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtrTSAFRDLQGQLAHAKKQQELQQRYAElcaaAITCT 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1347 VNDHTSKVRDLTSQVRHL--EDELADTKGNLVQKEMdlESTQNRLRSLEdQHSTLQSDANKWRGELDAALRENDILKSNN 1424
Cdd:TIGR00618  451 AQCEKLEKIHLQESAQSLkeREQQLQTKEQIHLQET--RKKAVVLARLL-ELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1425 TNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDtkltKLRNELQDTNDKLITS 1504
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP----NLQNITVRLQDLTEKL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1505 DTERNALRNELQKL---------SQELKFGNEQIQRKSDEYQTTIDDLA----------HSHRVSED------SRLNALQ 1559
Cdd:TIGR00618  604 SEAEDMLACEQHALlrklqpeqdLQDVRLHLQQCSQELALKLTALHALQltltqervreHALSIRVLpkellaSRQLALQ 683

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 25151529   1560 ELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSAN 1611
Cdd:TIGR00618  684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA 735
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 652-851 4.18e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  652 ADAKREISNLQKSVDEAERNSRRTDDKLRASEAERVAAEKARKFLEDELAKLQAsfqksstdDARKLRDEMDEhtnsIQE 731
Cdd:COG3883   12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQA--------EIDKLQAEIAE----AEA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  732 EFKTRIDELNRRVENLLRENNR-------LKSE-----------VNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIR 793
Cdd:COG3883   80 EIEERREELGERARALYRSGGSvsyldvlLGSEsfsdfldrlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAEL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  794 RNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDE 851
Cdd:COG3883  160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1221-1365 4.26e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 4.26e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    1221 DKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQladsLNRENELEREKRDYDEkiNSLYGQNQKIKDEwddfrnd 1300
Cdd:smart00787  150 DENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEE----LRQLKQLEDELEDCDP--TELDRAKEKLKKL------- 216

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529    1301 aDKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVND---HT-SKVRDLTSQVRHLE 1365
Cdd:smart00787  217 -LQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQcrgFTfKEIEKLKEQLKLLQ 284
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1752-2080 4.46e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 4.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1752 ERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRD----------- 1820
Cdd:COG3096  279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEkieryqedlee 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1821 -EERRQMKSKMVA-AELQARGKEAQLRHLNEQLKNLRTDL--------------------------------------DN 1860
Cdd:COG3096  359 lTERLEEQEEVVEeAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldvqqtraiqyqqavqalekaralcglpdltpEN 438

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1861 AHTDIRSLRDKEEQWDSSRFQLETKMRESDSDTNK----YQL--QIASfESERQILTEKIKELdgaLRLSDSKvQDMKDD 1934
Cdd:COG3096  439 AEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQfekaYELvcKIAG-EVERSQAWQTAREL---LRRYRSQ-QALAQR 513

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1935 TDKLRRDLTKAESVENELRKTIDIQSKTSHEYQLLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNR 2014
Cdd:COG3096  514 LQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRAR 593

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2015 VSELQ------RQLQDA-NTEKNRVEDRFLSVEKVVNTMRTTETDLRqQLETAKNEKRVATKELEDLKRRLAQ 2080
Cdd:COG3096  594 IKELAarapawLAAQDAlERLREQSGEALADSQEVTAAMQQLLERER-EATVERDELAARKQALESQIERLSQ 665
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1265-1589 4.46e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 4.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1265 RENELE--REKRD-----YDE------KINSLYGQ-NQKIKDEWDD-FRNDADKEIQKWKTDAYTVRSEAKALETTNTAL 1329
Cdd:COG3096  783 REKRLEelRAERDelaeqYAKasfdvqKLQRLHQAfSQFVGGHLAVaFAPDPEAELAALRQRRSELERELAQHRAQEQQL 862

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1330 KAQLQAANDRIDHLTKTV-NDHTSKVRDLTSQVRHLEDELADTKgnlvQKEMDLESTQNRLRSLEDQHSTLQSDAnkwrg 1408
Cdd:COG3096  863 RQQLDQLKEQLQLLNKLLpQANLLADETLADRLEELREELDAAQ----EAQAFIQQHGKALAQLEPLVAVLQSDP----- 933

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1409 eldaalRENDILKSNNTNMETDLTRLKNRLksaeDALKELKNSLSH--------AKTEKERLQNAFREKTKQADhlnQLA 1480
Cdd:COG3096  934 ------EQFEQLQADYLQAKEQQRRLKQQI----FALSEVVQRRPHfsyedavgLLGENSDLNEKLRARLEQAE---EAR 1000

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1481 SQFDTKLTKLRNELQDTNDKLITSDTERNALRNELQKLSQELkfgnEQIQRKSDeyqTTIDDLAHSHRvseDSRLNALQE 1560
Cdd:COG3096 1001 REAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL----EELGVQAD---AEAEERARIRR---DELHEELSQ 1070

                        330       340       350
                 ....*....|....*....|....*....|...
gi 25151529 1561 LEARKYEIN-DLTSR---LDSTEQRLATLQQDY 1589
Cdd:COG3096 1071 NRSRRSQLEkQLTRCeaeMDSLQKRLRKAERDY 1103
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
870-1040 4.54e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  870 RQDLEKNGARNNDELDKLRQTISDYESQINLLRRHND--ELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEK 947
Cdd:COG3206  170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  948 QDILNQ--KLKLDGDVQALKETIRKLENELEKLR-----------------NENKELVGKEA-RARDAANQQLSRANLLN 1007
Cdd:COG3206  250 GSGPDAlpELLQSPVIQQLRAQLAELEAELAELSarytpnhpdvialraqiAALRAQLQQEAqRILASLEAELEALQARE 329

                        170       180       190
                 ....*....|....*....|....*....|...
gi 25151529 1008 KELEDTKQDLKHSTDVNKQLEQDIRDLKERLAN 1040
Cdd:COG3206  330 ASLQAQLAQLEARLAELPELEAELRRLEREVEV 362
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 1980-2220 4.56e-03

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 41.97  E-value: 4.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1980 LNGANNRKQQLenellNVRSEVRDYKQRVHDVNNRVSELQRQLQDAntEKNRVEDRFLS----VEKVVNTMRTTETDLRQ 2055
Cdd:pfam15742  100 LKQAQSIKSQN-----SLQEKLAQEKSRVADAEEKILELQQKLEHA--HKVCLTDTCILekkqLEERIKEASENEAKLKQ 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2056 QLETAKNEKRVATKELEDLKRRLAQLEN-----ERRNSSQLSDGWKKEkiTLLKKielLENEKRRTDAAIRetaLQREAI 2130
Cdd:pfam15742  173 QYQEEQQKRKLLDQNVNELQQQVRSLQDkeaqlEMTNSQQQLRIQQQE--AQLKQ---LENEKRKSDEHLK---SNQELS 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   2131 EKsLNAMERENKELYKNCAQLQQQIAQlEMENGNrileltnkqrEEQERQLIRMRQEKGQIEKVIENRERthrnRIKQLE 2210
Cdd:pfam15742  245 EK-LSSLQQEKEALQEELQQVLKQLDV-HVRKYN----------EKHHHHKAKLRRAKDRLVHEVEQRDE----RIKQLE 308

                          250
                   ....*....|
gi 25151529   2211 DQIAILRDQL 2220
Cdd:pfam15742  309 NEIGILQQQS 318
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1736-1951 4.60e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1736 EGTLQSLLNKIEKLEMERNELRDTLARMKKKttethttINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEA 1815
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAE-------LEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1816 LKQ--RDEERRQMKSKMVAAELQARG----------KEAQLRHLNEQLKNLRTDLDNAHTDIRSLRDKEEQWDSSRFQLE 1883
Cdd:COG3883   88 LGEraRALYRSGGSVSYLDVLLGSESfsdfldrlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529 1884 TKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENE 1951
Cdd:COG3883  168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
mukB PRK04863
chromosome partition protein MukB;
1774-1918 4.60e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 4.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1774 INQKETRYRNIEDNLQDAEEERRALESRLQ---------SAKTLLRSQE--EALKQRDEERRQMKSKmvaAELQARGKEA 1842
Cdd:PRK04863  937 FEQLKQDYQQAQQTQRDAKQQAFALTEVVQrrahfsyedAAEMLAKNSDlnEKLRQRLEQAEQERTR---AREQLRQAQA 1013

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1843 QLRHLNEqlknLRTDLDNAHTDIRSLRDK----------------EEQWDSSRFQLETKMRESDSDTNKYQLQIASFESE 1906
Cdd:PRK04863 1014 QLAQYNQ----VLASLKSSYDAKRQMLQElkqelqdlgvpadsgaEERARARRDELHARLSANRSRRNQLEKQLTFCEAE 1089

                         170
                  ....*....|..
gi 25151529  1907 RQILTEKIKELD 1918
Cdd:PRK04863 1090 MDNLTKKLRKLE 1101
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1991-2357 4.84e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1991 ENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRflsvekvVNTMRTTETDLRQQLETAknEKRVATKE 2070
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-------LEALQAEIDKLQAEIAEA--EAEIEERR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2071 lEDLKRRLAQLENERRNSSQL-----SDGWKkekiTLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMErenkely 2145
Cdd:COG3883   86 -EELGERARALYRSGGSVSYLdvllgSESFS----DFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------- 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2146 kncaqlqqqiaqlemengnrileltnKQREEQERQLIRMRQEKGQIEKVIENRErthrNRIKQLEDQIAILRDQLDGERR 2225
Cdd:COG3883  154 --------------------------AKLAELEALKAELEAAKAELEAQQAEQE----ALLAQLSAEEAAAEAQLAELEA 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 2226 RRREYVDRSMVNDIGRLGSNVLGIRNSYGDNSIDAIINGGSRSVGFYPRSTFASNPLTPPLGSSTPTHRPHVTDFRSAVD 2305
Cdd:COG3883  204 ELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAG 283

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 25151529 2306 AG-SSYRRPISTIEDSGSVYGGSIRDRDSVYGGGGRDSSFGTRAGDSISRAGV 2357
Cdd:COG3883  284 GGaGGAGGGGGGGGAASGGSGGGSGGAGGVGSGGGAGAVVGGASAGGGGGSGG 336
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 676-974 5.09e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 5.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   676 DDKLRASEAERV--AAEKARKfLEDELAKLQASFQKSSTDDARKlrdemdehtnsiQEEFKTRIDELNRRVENLLrenNR 753
Cdd:PRK05771   34 EDLKEELSNERLrkLRSLLTK-LSEALDKLRSYLPKLNPLREEK------------KKVSVKSLEELIKDVEEEL---EK 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   754 LKSEVNPLKDKYRDLENEynstQRRIEEKETQIRYsddiRRNIQKDLDDLREkYDRVHTdnekILGELEHAQKAAHLAEQ 833
Cdd:PRK05771   98 IEKEIKELEEEISELENE----IKELEQEIERLEP----WGNFDLDLSLLLG-FKYVSV----FVGTVPEDKLEELKLES 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   834 QLKEIKIQRDDYQKqkdehaRHLFDIRHKlETEIKGRQDLEKNGARNND--ELDKLRQTISDYESQINLLRRHNDELDTT 911
Cdd:PRK05771  165 DVENVEYISTDKGY------VYVVVVVLK-ELSDEVEEELKKLGFERLEleEEGTPSELIREIKEELEEIEKERESLLEE 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25151529   912 IKghqGKITHLENELHSRSGEIEklndlnqrLQKEKQDILNQKLK------LDG-----DVQALKETIRKLENE 974
Cdd:PRK05771  238 LK---ELAKKYLEELLALYEYLE--------IELERAEALSKFLKtdktfaIEGwvpedRVKKLKELIDKATGG 300
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 716-1044 5.18e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 5.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   716 RKLRDEMDeHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLeneynstQRRIEEKETQirYSDDIRrN 795
Cdd:PRK04778  101 RKAKHEIN-EIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYREL-------RKSLLANRFS--FGPALD-E 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   796 IQKDLDDLREKYDRVHTDNEKilGELEHAQKAAHLAEQQLKEIKIQRDD----YQKQKDEHARHLFDIRHkleteikGRQ 871
Cdd:PRK04778  170 LEKQLENLEEEFSQFVELTES--GDYVEAREILDQLEEELAALEQIMEEipelLKELQTELPDQLQELKA-------GYR 240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   872 DLEKNGARnndeLDKLrqtisDYESQINLLRRHNDELDTTIKghQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDIL 951
Cdd:PRK04778  241 ELVEEGYH----LDHL-----DIEKEIQDLKEQIDENLALLE--ELDLDEAEEKNEEIQERIDQLYDILEREVKARKYVE 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   952 NQKLKLDGDVQALKETIRKLENELEKLrNENKELVGKEARARDAANQQLSRanlLNKELEDTKQDLKHSTDVNKQLEQDI 1031
Cdd:PRK04778  310 KNSDTLPDFLEHAKEQNKELKEEIDRV-KQSYTLNESELESVRQLEKQLES---LEKQYDEITERIAEQEIAYSELQEEL 385

                         330
                  ....*....|...
gi 25151529  1032 RDLKERLANIGKG 1044
Cdd:PRK04778  386 EEILKQLEEIEKE 398
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1898-2028 5.31e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 5.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1898 LQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDI------QSKTSHEYQLLkd 1971
Cdd:COG1579   17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKyeeqlgNVRNNKEYEAL-- 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529 1972 qllntQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTE 2028
Cdd:COG1579   95 -----QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE 146
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
711-830 5.48e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 5.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  711 STDDARKLRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKetqIRYSD 790
Cdd:COG2433  389 ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERRE---IRKDR 465

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 25151529  791 DIRRnIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHL 830
Cdd:COG2433  466 EISR-LDREIERLERELEEERERIEELKRKLERLKELWKL 504
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 1417-1523 5.59e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.64  E-value: 5.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   1417 NDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAF-REKTKQADHLNQLASQFDTKLTKLRNELQ 1495
Cdd:TIGR04320  242 NKFDKTPIPNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYaAAQAALATAQKELANAQAQALQTAQNNLA 321

                           90       100
                   ....*....|....*....|....*...
gi 25151529   1496 DTNDKLITSDTERNALRNELQKLSQELK 1523
Cdd:TIGR04320  322 TAQAALANAEARLAKAKEALANLNADLA 349
HemX COG2959
Proteobacterial HemX domain, involved in 2-ketogluconate production (unrelated to B. subtilis ...
 883-980 5.85e-03

Proteobacterial HemX domain, involved in 2-ketogluconate production (unrelated to B. subtilis HemX, COG0755, no evidence of involvement in heme biosynthesis) [General function prediction only];


Pssm-ID: 442199 [Multi-domain]  Cd Length: 361  Bit Score: 41.49  E-value: 5.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  883 ELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQD------------I 950
Cdd:COG2959   61 ELAQLAQQLAALQQQAQELRALAQQLQELLQQLAARLAQLEQRLAELQQQLAALQQLLQSLSGSSRDdwllaeaeyllrL 140

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 25151529  951 LNQKLKLDGDVQ----ALKE--------------TIRK-LENELEKLRN 980
Cdd:COG2959  141 AGQQLQLEGDVKtalaALQSadarlarlndpsllPVRRaIARDIARLRA 189
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1144-1828 6.13e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 6.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1144 DDELVEHKIREVN--DRWKRELERLENEKDDLERRIRELEDELSQigrgndktENDITELKRKHAAEIDKLKSDISALHD 1221
Cdd:PRK03918  143 SDESREKVVRQILglDDYENAYKNLGEVIKEIKRRIERLEKFIKR--------TENIEELIKEKEKELEEVLREINEISS 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1222 KhLSDLDDEKEQYGKAVENLKSveddLRDKLNNLEKQLAdslnrenELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDA 1301
Cdd:PRK03918  215 E-LPELREELEKLEKEVKELEE----LKEEIEELEKELE-------SLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1302 dKEIQ--KWKTDAYT--------VRSEAKALETTNTALKAQLQAANDRIDHLtktvNDHTSKVRDLTSQVRHLEDELADT 1371
Cdd:PRK03918  283 -KELKelKEKAEEYIklsefyeeYLDELREIEKRLSRLEEEINGIEERIKEL----EEKEERLEELKKKLKELEKRLEEL 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1372 KGNlVQKEMDLESTQNRLRSLEDQHSTLQSDanKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNS 1451
Cdd:PRK03918  358 EER-HELYEEAKAKKEELERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1452 -----LSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTnDKLITSDTERNALR---NELQKLSQELK 1523
Cdd:PRK03918  435 kgkcpVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKelaEQLKELEEKLK 513

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1524 -FGNEQIQRKSDEYQTTIDDLA--HSHRVSEDSRLNALQELEARKYEINdltSRLDSTEQRLATLQQDYIKAD-SERDIL 1599
Cdd:PRK03918  514 kYNLEELEKKAEEYEKLKEKLIklKGEIKSLKKELEKLEELKKKLAELE---KKLDELEEELAELLKELEELGfESVEEL 590

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1600 SDALRRFQSSANRVInfhtfvdggagyvdgvpggtsvigggpsaqrsgaydpssggvigsgisggpggsdfgreieigrg 1679
Cdd:PRK03918  591 EERLKELEPFYNEYL----------------------------------------------------------------- 605

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1680 dsdqsdvayprsvpfppsadfssgrpgaasaggrvinnldgtttvnmnggfDIANLEGTLQSLLNKIEKLEMERNELRDT 1759
Cdd:PRK03918  606 ---------------------------------------------------ELKDAEKELEREEKELKKLEEELDKAFEE 634

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1760 LARMKKKTTETHTTINQ------------KETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMK 1827
Cdd:PRK03918  635 LAETEKRLEELRKELEElekkyseeeyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714


                  .
gi 25151529  1828 S 1828
Cdd:PRK03918  715 K 715
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
922-1346 6.26e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 6.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  922 LENELHSRSGEIEKLNDLNQRLQKEKQDILNQKLKL----DGDVQALKETIRKLENELEKLRNENKELVGKEARARDAAN 997
Cdd:COG4717   47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEaeekEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  998 -----QQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLKERLANIGKGGRISRDSTTGTDGGAFGD---------- 1062
Cdd:COG4717  127 llplyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDlaeeleelqq 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1063 ---------RSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDIPSSGDVIHGRDGRDGRDAGNRGTHT---------I 1124
Cdd:COG4717  207 rlaeleeelEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlflvlglL 286

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1125 TNTKERIERIEKNILDRYHDDELVEHKIREVNDRWKRELERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRK 1204
Cdd:COG4717  287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1205 -HAAEIDKLKSDISALHDKHLSDLDDEKEQYGKAVENLKSVEDDLRDKLNNLEKQLADS-----LNRENELEREKRDYDE 1278
Cdd:COG4717  367 eLEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALdeeelEEELEELEEELEELEE 446

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529 1279 KINSLYGQNQKIKDEWDDFRNdaDKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKT 1346
Cdd:COG4717  447 ELEELREELAELEAELEQLEE--DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1165-1275 6.27e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1165 RLEN-----EKDDLERRIRELEDELSQIGRgndktENDITELKRKHA--AEIDKLKSDISALHDKHLSdlddEKEQYGKa 1237
Cdd:COG0542  403 RMEIdskpeELDELERRLEQLEIEKEALKK-----EQDEASFERLAElrDELAELEEELEALKARWEA----EKELIEE- 472

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 25151529 1238 VENLKSVEDDLRDKLNNLEKQLADSLNRENELEREKRD 1275
Cdd:COG0542  473 IQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE 510
46 PHA02562
endonuclease subunit; Provisional
 1420-1609 6.98e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 6.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1420 LKSNNTNMETDLTRLKNRLKSAEDALKELKNSlshAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTND 1499
Cdd:PHA02562  179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK---NGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1500 KLITSDTERNALRNELQKLSQELKFGNE-------------------QIQRKSDEYQTTIDDLahshrvsedsrLNALQE 1560
Cdd:PHA02562  256 ALNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctqqisegpdritKIKDKLKELQHSLEKL-----------DTAIDE 324

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 25151529  1561 LEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSS 1609
Cdd:PHA02562  325 LEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAE 373
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 709-1599 7.19e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 41.74  E-value: 7.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   709 KSSTDDARKLRDEmDEHTNSIQEEFKTRIDELNRRVENLlRENNRLKSEVNPLKDKYRDLENE--YNSTQRRIEEKETQI 786
Cdd:PTZ00440  546 KYYLQSIETLIKD-EKLKRSMKNDIKNKIKYIEENVDHI-KDIISLNDEIDNIIQQIEELINEalFNKEKFINEKNDLQE 623

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   787 RYSDDIRRNIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLaeqqLKEIKiqrDDYQKQKDEHARHLFDIRHKLETE 866
Cdd:PTZ00440  624 KVKYILNKFYKGDLQELLDELSHFLDDHKYLYHEAKSKEDLQTL----LNTSK---NEYEKLEFMKSDNIDNIIKNLKKE 696

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   867 IKGRQDLEKNGArnNDELDKLRQTISDyesQINLLRRHNDELDTTIKGHQGKITHLEN--------------ELHSRSGE 932
Cdd:PTZ00440  697 LQNLLSLKENII--KKQLNNIEQDISN---SLNQYTIKYNDLKSSIEEYKEEEEKLEVykhqiinrknefilHLYENDKD 771

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529   933 IEKLNDLNQRLQKEKQDILNQKLKLDGDVQALKETIRKLENELEKLRNENKELVGKEARARDAANQQLSRANLLNKELeD 1012
Cdd:PTZ00440  772 LPDGKNTYEEFLQYKDTILNKENKISNDINILKENKKNNQDLLNSYNILIQKLEAHTEKNDEELKQLLQKFPTEDENL-N 850

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1013 TKQDLKHSTDVNKQLEQDIRDLKERLANIGkggriSRDSTTGTDGGAFGDRSSVADPSRTRGaagstvfvpaaeDIESRG 1092
Cdd:PTZ00440  851 LKELEKEFNENNQIVDNIIKDIENMNKNIN-----IIKTLNIAINRSNSNKQLVEHLLNNKI------------DLKNKL 913

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1093 GGEIDIPSSGDVIhgrdgrdgrdAGNRGTHTITNTKERIERIEKNILDRYHDD---------ELVEHKIREVNDRWKREL 1163
Cdd:PTZ00440  914 EQHMKIINTDNII----------QKNEKLNLLNNLNKEKEKIEKQLSDTKINNlkmqiektlEYYDKSKENINGNDGTHL 983

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1164 ERLENEKDDLERRIRELEDELSQIGRGNDKTENDITELKRKHAAEIDKL----KSDISALHDKHLSDLDDEKEQYGK--A 1237
Cdd:PTZ00440  984 EKLDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKQHDDIIELIDKLikekGKEIEEKVDQYISLLEKMKTKLSSfhF 1063

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1238 VENLKSVEDDL-RDKLNNLEKQLADSLNR----ENELEREKRDYDEKINSLYGQNQKIKDEWDDFRNDADKEIQKWKTDA 1312
Cdd:PTZ00440 1064 NIDIKKYKNPKiKEEIKLLEEKVEALLKKidenKNKLIEIKNKSHEHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTL 1143

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1313 YTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLEST------Q 1386
Cdd:PTZ00440 1144 KELENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKSKTIMEEIESYKKDIDQVKKNMSKERNDHLTTfeynayY 1223

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1387 NRLRSLEDQHSTLQSDANKWRGELDAAlRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKN------SLSHAKTEKE 1460
Cdd:PTZ00440 1224 DKATASYENIEELTTEAKGLKGEANRS-TNVDELKEIKLQVFSYLQQVIKENNKMENALHEIKNmyefliSIDSEKILKE 1302

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1461 RLQNAFR------EKTKQADHLNQLASQFDTKLTKLRNE----LQDTNDKLItsDTERNALRNELQKLSQELKFGNEQIQ 1530
Cdd:PTZ00440 1303 ILNSTKKaeefsnDAKKELEKTDNLIKQVEAKIEQAKEHknkiYGSLEDKQI--DDEIKKIEQIKEEISNKRKEINKYLS 1380

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529  1531 RKSDEYQTTIDDLAHSHR----VSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDIL 1599
Cdd:PTZ00440 1381 NIKSNKEKCDLHVRNASRgkdkIDFLNKHEAIEPSNSKEVNIIKITDNINKCKQYSNEAMETENKADENNDSI 1453
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
796-1098 7.47e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 7.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  796 IQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDEharhlfdIRHKLETEIKGRQDLEK 875
Cdd:COG4372   29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE-------LNEQLQAAQAELAQAQE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  876 NGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIKGHQGKITHLENELHSRSGEIEKLNDLNQRLQKEKQDILNQKL 955
Cdd:COG4372  102 ELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  956 KLDGDvQALKETIRKLENELEKLRNENKELvgKEARARDAANQQLSRANLLNKELEDTKQDLKHSTDVNKQLEQDIRDLK 1035
Cdd:COG4372  182 EQALD-ELLKEANRNAEKEEELAEAEKLIE--SLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILK 258

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25151529 1036 ERLANIGKGGRISRDSTTGTDGGAFGDRSSVADPSRTRGAAGSTVFVPAAEDIESRGGGEIDI 1098
Cdd:COG4372  259 EIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAAL 321
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1428-1603 7.74e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 7.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1428 ETDLTRLKNRLKSAEDALKELKNSLSHAKTEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELqdtndKLITSDTE 1507
Cdd:COG1579   16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL-----GNVRNNKE 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1508 RNALRNELQKLSQELKFGNEQIQR---KSDEYQTTIDDLAhshrvsedsrlnalQELEARKYEINDLTSRLDsteQRLAT 1584
Cdd:COG1579   91 YEALQKEIESLKRRISDLEDEILElmeRIEELEEELAELE--------------AELAELEAELEEKKAELD---EELAE 153

                        170
                 ....*....|....*....
gi 25151529 1585 LQQDYIKADSERDILSDAL 1603
Cdd:COG1579  154 LEAELEELEAEREELAAKI 172
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 319-429 8.08e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529    319 NANYEMIARLDEERRRSDEYRMQWENERQKSLSL--EDENDRLRREFERYANDSKDKEKTFINReRNLAQYLSDEQRKML 396
Cdd:pfam17380  431 EARQREVRRLEEERAREMERVRLEEQERQQQVERlrQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERKQAMI 509

                           90       100       110
                   ....*....|....*....|....*....|...
gi 25151529    397 DLWTELQRVRKQFSDLKTHTEEDLDKQKAEFTR 429
Cdd:pfam17380  510 EEERKRKLLEKEMEERQKAIYEEERRREAEEER 542
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 714-851 9.28e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 9.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  714 DARKLRDEMDEHTNSIQEEFKTRIDELNRRVEnllrennrLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQIRYSDDIR 793
Cdd:COG3096  279 ERRELSERALELRRELFGARRQLAEEQYRLVE--------MARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIE 350

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 25151529  794 RnIQKDLDDLREKYDRVHTDNEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDE 851
Cdd:COG3096  351 R-YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDV 407
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1137-1322 9.46e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 41.21  E-value: 9.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1137 NILDRY-HDDELVEhKIREVNDRW---KRELERLENEKDDLERRIRELEDELSQIGRGNDKtENDITELKRKHA--AEID 1210
Cdd:COG0497  145 ELLDAFaGLEELLE-EYREAYRAWralKKELEELRADEAERARELDLLRFQLEELEAAALQ-PGEEEELEEERRrlSNAE 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529 1211 KLKSDISALHD-----------------KHLSDLDDEKEQYGKAVENLKS-------VEDDLRDKLNNLE---KQLADSL 1263
Cdd:COG0497  223 KLREALQEALEalsggeggaldllgqalRALERLAEYDPSLAELAERLESalieleeAASELRRYLDSLEfdpERLEEVE 302

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 25151529 1264 NRENELEREKRDYDEKINSLYGQNQKIKDEWDDFrNDADKEIQKWKTDAYTVRSEAKAL 1322
Cdd:COG0497  303 ERLALLRRLARKYGVTVEELLAYAEELRAELAEL-ENSDERLEELEAELAEAEAELLEA 360
46 PHA02562
endonuclease subunit; Provisional
 1936-2148 9.81e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 9.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  1936 DKLRRDLTKaesVENELRKTIDIQskTSHEYQLLKDQ--LLNTQNELNGANN-RKQQLENELLNvrsEVRDYKQRVHDVN 2012
Cdd:PHA02562  169 DKLNKDKIR---ELNQQIQTLDMK--IDHIQQQIKTYnkNIEEQRKKNGENIaRKQNKYDELVE---EAKTIKAEIEELT 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  2013 NRVSELQRQ-------LQDANTEKNRVEDRFLSVEKVVNTMRTTET--DLRQQLETA-------KNEKRVATKELEDLKR 2076
Cdd:PHA02562  241 DELLNLVMDiedpsaaLNKLNTAAAKIKSKIEQFQKVIKMYEKGGVcpTCTQQISEGpdritkiKDKLKELQHSLEKLDT 320

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25151529  2077 R---LAQLENE-RRNSSQLSDgwKKEKITLLKK-IELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNC 2148
Cdd:PHA02562  321 AideLEEIMDEfNEQSKKLLE--LKNKISTNKQsLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTK 395
ClyA_Cry6Aa-like cd22656
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ...
 718-913 9.99e-03

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.


Pssm-ID: 439154 [Multi-domain]  Cd Length: 309  Bit Score: 40.43  E-value: 9.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  718 LRDEMDEHTNSIQEEFKTRIDELNRRVENLLRENNRLKSEVNPLKDKYRDLENEYNSTQRRIEEKETQI--RYSDDIRRN 795
Cdd:cd22656   97 LELIDDLADATDDEELEEAKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALkdLLTDEGGAI 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25151529  796 IQKDLDDLREKYDRVHTD-NEKILGELEHAQKAAHLAEQQLKEIKIQRDDYQKQKDeharHLFDIRHKLETEIKGRQDLE 874
Cdd:cd22656  177 ARKEIKDLQKELEKLNEEyAAKLKAKIDELKALIADDEAKLAAALRLIADLTAADT----DLDNLLALIGPAIPALEKLQ 252

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 25151529  875 KNGARNNDELDKLRQTISDYESQINLLRRHNDELDTTIK 913
Cdd:cd22656  253 GAWQAIATDLDSLKDLLEDDISKIPAAILAKLELEKAIE 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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