NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17564680|ref|NP_507237|]
View 

DUF38 domain-containing protein [Caenorhabditis elegans]

Protein Classification

FTH domain-containing protein( domain architecture ID 707519)

FTH (FOG-2 homology) domain-containing protein may be involved in protein-protein interactions

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FTH super family cl28746
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 136-248 2.29e-13

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


The actual alignment was detected with superfamily member pfam01827:

Pssm-ID: 396410  Cd Length: 141  Bit Score: 66.06  E-value: 2.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564680   136 SLTKMLKAMMRALMKKLEVEVFKIvyngkeEEVMCLLPYFEPGYLRRICLFNPLYVSPtvIDNIITTEQWKQAKELNTMT 215
Cdd:pfam01827   6 SFLNILKSKKCLHVKEISLSGLSF------SEVASILPYFDAGTLEEIELSSESDEDQ--FEEIVELEQWKNAKSLKIEG 77

                          90       100       110
                  ....*....|....*....|....*....|...
gi 17564680   216 GEPVAFPVESHAHFESLRIRIPELKQIDVILLV 248
Cdd:pfam01827  78 SSLSSFPIEHLFHFEEFDIKLDSFSVEDAIKIR 110
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 136-248 2.29e-13

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 66.06  E-value: 2.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564680   136 SLTKMLKAMMRALMKKLEVEVFKIvyngkeEEVMCLLPYFEPGYLRRICLFNPLYVSPtvIDNIITTEQWKQAKELNTMT 215
Cdd:pfam01827   6 SFLNILKSKKCLHVKEISLSGLSF------SEVASILPYFDAGTLEEIELSSESDEDQ--FEEIVELEQWKNAKSLKIEG 77

                          90       100       110
                  ....*....|....*....|....*....|...
gi 17564680   216 GEPVAFPVESHAHFESLRIRIPELKQIDVILLV 248
Cdd:pfam01827  78 SSLSSFPIEHLFHFEEFDIKLDSFSVEDAIKIR 110
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 136-248 2.29e-13

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 66.06  E-value: 2.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564680   136 SLTKMLKAMMRALMKKLEVEVFKIvyngkeEEVMCLLPYFEPGYLRRICLFNPLYVSPtvIDNIITTEQWKQAKELNTMT 215
Cdd:pfam01827   6 SFLNILKSKKCLHVKEISLSGLSF------SEVASILPYFDAGTLEEIELSSESDEDQ--FEEIVELEQWKNAKSLKIEG 77

                          90       100       110
                  ....*....|....*....|....*....|...
gi 17564680   216 GEPVAFPVESHAHFESLRIRIPELKQIDVILLV 248
Cdd:pfam01827  78 SSLSSFPIEHLFHFEEFDIKLDSFSVEDAIKIR 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH