|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
114-649 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 645.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 114 RHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTS---VHYCPATNKVLEKKFAdFTMLDTAVtnnnyPTEDENKNPLE 190
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGR-ETEPTVCP-----PRECQSPTPFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 191 TEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGVFRVLP-NKQNGVSSG--SFRSIIII 267
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGlpVFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 268 NHIQML--------SKEVIPNFEPQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLR 339
Cdd:smart00350 155 NHVRKLdykrsfedSSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 340 GDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSD 419
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 420 IDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDAN 499
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 500 VAEHVLKLHTYRTQGEADgtvlpmgggvetistinmetkkasssiyeentqwagiQDTKILTMDFMRKYIHLARS-VQPK 578
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDE-------------------------------------AFEPPLSQEKLRKYIAYAREkIKPK 437
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17562700 579 LTDEATEYISEVYADIRSFDItKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:smart00350 438 LSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
301-649 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 559.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVG 380
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 381 LTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYG 460
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 461 RYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYrtqgeadgtvlpmgggvetistinmetkka 540
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 541 sssiyeentqwagiqdtkiltMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLI 619
Cdd:cd17754 211 ---------------------IKFLRKYIHYAKErIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITARTLETLI 269
|
330 340 350
....*....|....*....|....*....|
gi 17562700 620 RLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:cd17754 270 RLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
18-645 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 550.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 18 KQEITEQYLNFLDNqadtFHYRQKIVKMMND-GESR-LVMNLDEIREILPERAEGLLTQSVLemncLQSALQMAINRSDV 95
Cdd:COG1241 2 ESDLVDKFEEFLRR----YKYRDEILELAQEyPEKRsLVVDYNDLYSFDPDLADDLLENPDE----VLEAAEEALREIDL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 96 Q--AVVKTGFHVGFEGTFgeRHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCP---ATNKVLEK--KFadft 168
Cdd:COG1241 74 EpyDVSLGDAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPrcgTETYVPQTgeKL---- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 169 mldtavtnnNYPTEDEN---KNPLETEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGV 245
Cdd:COG1241 148 ---------QEPHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 246 FRVLPNKQNGVSSGSFRSIIIINHIQMLSKEvipnFE-----PQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKAL 320
Cdd:COG1241 219 LRIEQRTSGRGKSTIFDLYLEANSIEVEEKE----FEeieitEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAI 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 321 LCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTD-PDSGERRLEAG 399
Cdd:COG1241 295 ALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRWTLEAG 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 400 AMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLL 479
Cdd:COG1241 375 ALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLL 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 480 SRFDLIFVLLDEHDADKDANVAEHVLKLHTyrtqgeadgtvlpmgGGVETISTINMETKKASSSIyeentqwagiqdtki 559
Cdd:COG1241 455 SRFDLIFVLRDKPDEERDRELARHILKVHR---------------AGELLEQEIEEETEEVKPEI--------------- 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 560 lTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIRSfdiTKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVERED 638
Cdd:COG1241 505 -DPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRK---KGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEED 580
|
....*..
gi 17562700 639 TEKAYNL 645
Cdd:COG1241 581 AERAIRL 587
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
21-645 |
1.50e-174 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 518.71 E-value: 1.50e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 21 ITEQYLNFLDNQAD---TFHYRQKIVKMMNDGESRLVMNLDEIREILPERAEGLL--TQSVLEMncLQSALQMAINRSD- 94
Cdd:NF040949 1 LGEKFKEFIRTFRDsfgNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIekPDEVLPA--ASKALKEIVEEEDp 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 95 --VQAVVKtgFHVGFEGTFgeRHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCpatnkvlekkfadftmlDT 172
Cdd:NF040949 79 eyAEEVAK--FHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRC-----------------RD 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 173 AVTNNNYPTEDENKNP------------------LETEfgHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRV 234
Cdd:NF040949 138 CGCEFEWPEEEEESYEivepptvcpvcgkpgsfrLLQE--KSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTA 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 235 KPGDRVRIIGVFRVLPNKQNGV-SSGSFRSIIIINHIQMLSKEvipnFE-----PQDVKDVRKISKSRNPFELLARSLAP 308
Cdd:NF040949 216 RPGDRVTVTGILRIKPDSSLKKgSRPIFKNYIEANHIEVSQKE----LEeveitEEDEEKILELAKDPWIREKIIASIAP 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 309 SICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTD 388
Cdd:NF040949 292 SIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRD 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 389 PDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSP 468
Cdd:NF040949 372 KLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSV 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 469 MENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHtyrtqgeadgtvlpmgGGVETIstinmetkkasssiyeen 548
Cdd:NF040949 452 AENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----------------SGKEKV------------------ 497
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 549 tqwagiqdTKILTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAK 627
Cdd:NF040949 498 --------KPEIDPDLLKKYIAYARkYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAK 569
|
650
....*....|....*...
gi 17562700 628 ARFSKKVEREDTEKAYNL 645
Cdd:NF040949 570 MRLKDEVTAEDAERAIRL 587
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
285-508 |
7.13e-131 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 388.81 E-value: 7.13e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 285 DVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRM 364
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 365 APRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAK 444
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17562700 445 LNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLH 508
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
118-652 |
2.40e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 285.35 E-value: 2.40e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 118 PRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFADFT------MLDTAVTNNNYPTEDENKNPLET 191
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTcehyeyVIQGEVNEPLLCNECNSKYTFEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 192 EFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADL--------------------DLADRVKPGDRVRIIGVFRVLPN 251
Cdd:PTZ00111 298 NHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSglngeiymkdnevinlnlydDLIDSVKTGDRVTVVGILKVTPI 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 252 KQNGVS---SGSFRSIIIINHIQMLSK----EVIPNFE----PQDVKD--VRKISK-SRNP--FELLARSLAPSICGHEE 315
Cdd:PTZ00111 378 RTSTTRrtlKSLYTYFVNVIHVKVINStnanQPEKGLKylgnENDFSDlqVYKILElSRNPmiYRILLDSFAPSIKARNN 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 316 TKKALLCLLLGGMEKILNNG---------SRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVT 386
Cdd:PTZ00111 458 VKIGLLCQLFSGNKNSSDFNkspdacykvDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIK 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 387 -TDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPF 465
Cdd:PTZ00111 538 fNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKN 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 466 KSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKlhtyrtqgeaDGTVLPMGGgvetiSTINMETKKASSSIY 545
Cdd:PTZ00111 618 KAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK----------DFLLPHMTG-----SGNDEDTYDRSNTMH 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 546 EENTQWAGIQDTKILTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIR-------SFDITKTDQE------------ 605
Cdd:PTZ00111 683 VEDESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRqgnfqtsNLDELEHAQEdddddlyyqssg 762
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 17562700 606 -RTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEKAYNLLHFACFK 652
Cdd:PTZ00111 763 tRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ 810
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
114-649 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 645.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 114 RHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTS---VHYCPATNKVLEKKFAdFTMLDTAVtnnnyPTEDENKNPLE 190
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRAsftCEKCGATLGPEIQSGR-ETEPTVCP-----PRECQSPTPFS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 191 TEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGVFRVLP-NKQNGVSSG--SFRSIIII 267
Cdd:smart00350 75 LNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPyGFKLNTVKGlpVFATYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 268 NHIQML--------SKEVIPNFEPQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLR 339
Cdd:smart00350 155 NHVRKLdykrsfedSSFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 340 GDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSD 419
Cdd:smart00350 235 GDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 420 IDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDAN 499
Cdd:smart00350 315 SDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 500 VAEHVLKLHTYRTQGEADgtvlpmgggvetistinmetkkasssiyeentqwagiQDTKILTMDFMRKYIHLARS-VQPK 578
Cdd:smart00350 395 LAKHVVDLHRYSHPEEDE-------------------------------------AFEPPLSQEKLRKYIAYAREkIKPK 437
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17562700 579 LTDEATEYISEVYADIRSFDItKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:smart00350 438 LSEEAADKLVKAYVDLRKEDS-QTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
301-649 |
0e+00 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 559.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVG 380
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 381 LTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYG 460
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 461 RYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYrtqgeadgtvlpmgggvetistinmetkka 540
Cdd:cd17754 161 RYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------------------------ 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 541 sssiyeentqwagiqdtkiltMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLI 619
Cdd:cd17754 211 ---------------------IKFLRKYIHYAKErIKPKLTQEAAEYIAEEYADLRNDDNTKTDKARTSPITARTLETLI 269
|
330 340 350
....*....|....*....|....*....|
gi 17562700 620 RLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:cd17754 270 RLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
18-645 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 550.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 18 KQEITEQYLNFLDNqadtFHYRQKIVKMMND-GESR-LVMNLDEIREILPERAEGLLTQSVLemncLQSALQMAINRSDV 95
Cdd:COG1241 2 ESDLVDKFEEFLRR----YKYRDEILELAQEyPEKRsLVVDYNDLYSFDPDLADDLLENPDE----VLEAAEEALREIDL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 96 Q--AVVKTGFHVGFEGTFgeRHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCP---ATNKVLEK--KFadft 168
Cdd:COG1241 74 EpyDVSLGDAHVRITNLP--ETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPrcgTETYVPQTgeKL---- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 169 mldtavtnnNYPTEDEN---KNPLETEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGV 245
Cdd:COG1241 148 ---------QEPHECPGcgrQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 246 FRVLPNKQNGVSSGSFRSIIIINHIQMLSKEvipnFE-----PQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKAL 320
Cdd:COG1241 219 LRIEQRTSGRGKSTIFDLYLEANSIEVEEKE----FEeieitEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAI 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 321 LCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTD-PDSGERRLEAG 399
Cdd:COG1241 295 ALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRWTLEAG 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 400 AMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLL 479
Cdd:COG1241 375 ALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLL 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 480 SRFDLIFVLLDEHDADKDANVAEHVLKLHTyrtqgeadgtvlpmgGGVETISTINMETKKASSSIyeentqwagiqdtki 559
Cdd:COG1241 455 SRFDLIFVLRDKPDEERDRELARHILKVHR---------------AGELLEQEIEEETEEVKPEI--------------- 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 560 lTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIRSfdiTKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVERED 638
Cdd:COG1241 505 -DPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRK---KGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEED 580
|
....*..
gi 17562700 639 TEKAYNL 645
Cdd:COG1241 581 AERAIRL 587
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
21-645 |
1.50e-174 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 518.71 E-value: 1.50e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 21 ITEQYLNFLDNQAD---TFHYRQKIVKMMNDGESRLVMNLDEIREILPERAEGLL--TQSVLEMncLQSALQMAINRSD- 94
Cdd:NF040949 1 LGEKFKEFIRTFRDsfgNEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIekPDEVLPA--ASKALKEIVEEEDp 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 95 --VQAVVKtgFHVGFEGTFgeRHVNPRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCpatnkvlekkfadftmlDT 172
Cdd:NF040949 79 eyAEEVAK--FHVRFRNLP--RTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRC-----------------RD 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 173 AVTNNNYPTEDENKNP------------------LETEfgHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRV 234
Cdd:NF040949 138 CGCEFEWPEEEEESYEivepptvcpvcgkpgsfrLLQE--KSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTA 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 235 KPGDRVRIIGVFRVLPNKQNGV-SSGSFRSIIIINHIQMLSKEvipnFE-----PQDVKDVRKISKSRNPFELLARSLAP 308
Cdd:NF040949 216 RPGDRVTVTGILRIKPDSSLKKgSRPIFKNYIEANHIEVSQKE----LEeveitEEDEEKILELAKDPWIREKIIASIAP 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 309 SICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTD 388
Cdd:NF040949 292 SIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRD 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 389 PDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPFKSP 468
Cdd:NF040949 372 KLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSV 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 469 MENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHtyrtqgeadgtvlpmgGGVETIstinmetkkasssiyeen 548
Cdd:NF040949 452 AENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----------------SGKEKV------------------ 497
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 549 tqwagiqdTKILTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAK 627
Cdd:NF040949 498 --------KPEIDPDLLKKYIAYARkYVRPKLTEEAKKLIEDFYVEMRKSSKSSEDPDSPIPITARQLEALIRLSEAHAK 569
|
650
....*....|....*...
gi 17562700 628 ARFSKKVEREDTEKAYNL 645
Cdd:NF040949 570 MRLKDEVTAEDAERAIRL 587
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
301-646 |
3.54e-144 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 426.76 E-value: 3.54e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVG 380
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 381 LTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYG 460
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 461 RYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTQGEadgtvlpmgggvetistinmetkka 540
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEE------------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 541 sssiyeentQWAGIQDTKILTMDFMRKYIHLARSVQPKLTDEATEYISEVYADIRSfditKTDQERTMPVTARQLETLIR 620
Cdd:cd17706 216 ---------QVKPEEDGIPIDIELLRKYILYARQIHPKISEEAREKLVRWYVELRK----ESERRSTIPITARQLESVIR 282
|
330 340
....*....|....*....|....*.
gi 17562700 621 LSTAIAKARFSKKVEREDTEKAYNLL 646
Cdd:cd17706 283 LAEAHAKMRLSEVVTEEDVEEAIRLV 308
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
285-508 |
7.13e-131 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 388.81 E-value: 7.13e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 285 DVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRM 364
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 365 APRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAK 444
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17562700 445 LNARCSVLAAANPVYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLH 508
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
302-649 |
2.37e-129 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 388.31 E-value: 2.37e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 302 LARSLAPSICGHEETKKALLCLLLGGMEKIlNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGL 381
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 382 TAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGR 461
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 462 YNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYrtqGEADGTvlpmgggvetistinmetkkas 541
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQH---NKQPDS---------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 542 ssiyeentqwagiqDTKILTMDFMRKYIHLARSVQPKLTDEATEYISEVYADIRSfditktDQERTMP---VTARQLETL 618
Cdd:cd17758 216 --------------DFEPLDPKLLRAYIALAKRKRPTVPPALADYIVQAYVEMRQ------EAKRSKDftfTTPRTLLAI 275
|
330 340 350
....*....|....*....|....*....|.
gi 17562700 619 IRLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:cd17758 276 LRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
301-645 |
5.75e-124 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 374.80 E-value: 5.75e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVG 380
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 381 LTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYG 460
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 461 RYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHtyrtqgeadgtvlpmgggvetistinMETKKA 540
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIH--------------------------ASARKA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 541 SSSIYEENtqwagiqdtkILTMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSfDITKTDQER----TMPVTARQL 615
Cdd:cd17756 215 SQSQENEG----------EIPISKLKRYIAYCRAkCAPRLSEEAAEKLSNHYVTIRK-DVRQNELESdnrsSIPITVRQL 283
|
330 340 350
....*....|....*....|....*....|
gi 17562700 616 ETLIRLSTAIAKARFSKKVEREDTEKAYNL 645
Cdd:cd17756 284 EAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
302-646 |
1.34e-121 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 368.23 E-value: 1.34e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 302 LARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGL 381
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 382 TAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGR 461
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 462 YNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTqgeadgtvlpmgggvetistinmetkKAS 541
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE--------------------------EAI 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 542 SSIYeentqwagiqdtkilTMDFMRKYIHLARSVQPKLTDEATEYISEVYADIRSFDITKTDQeRTMPVTARQLETLIRL 621
Cdd:cd17757 216 EPPF---------------TAEQLKRYIAYARTFKPKLTKEAKDELVEQYKELRQDDASGSTR-SSYRITVRQLESLIRL 279
|
330 340
....*....|....*....|....*
gi 17562700 622 STAIAKARFSKKVEREDTEKAYNLL 646
Cdd:cd17757 280 SEAIARLHCSDEVTPEHVEEAARLL 304
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
300-646 |
5.62e-121 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 366.78 E-value: 5.62e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 300 ELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGV 379
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 380 GLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVY 459
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 460 GRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTyrtqgeadgtvlpmggGVETISTINmetkk 539
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHS----------------GGEMREIKP----- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 540 asssiyeentqwagiqdtkILTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIRSfdiTKTDQERTMPVTARQLETL 618
Cdd:cd17761 220 -------------------EIDPDLLRKYIAYARkNVRPVLTEEAKQLIKDFYVEMRK---SGQETPSPVPITARQLEAL 277
|
330 340
....*....|....*....|....*...
gi 17562700 619 IRLSTAIAKARFSKKVEREDTEKAYNLL 646
Cdd:cd17761 278 VRLSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
301-649 |
1.31e-114 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 350.20 E-value: 1.31e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKIL-NNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGV 379
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 380 GLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVY 459
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 460 GRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTQGEADGTVLPmgggvetistinmetkk 539
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLD----------------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 540 asssiyeentqwagiqdtkiltMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSFDitkTDQERTMPVTARQLETL 618
Cdd:cd17755 224 ----------------------VEVLTDYISYAREhIHPKLSEEAAQELVQAYVDMRKMG---SDARKRITATPRQLESL 278
|
330 340 350
....*....|....*....|....*....|.
gi 17562700 619 IRLSTAIAKARFSKKVEREDTEKAYNLLHFA 649
Cdd:cd17755 279 IRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
305-642 |
5.58e-110 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 339.04 E-value: 5.58e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 305 SLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAA 384
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 385 VTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNP 464
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 465 FKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTyRTQGEADgtvlpmgggvetistinmetKKASSSI 544
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHV-RSHPEND--------------------EDREGEE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 545 YEENTQWAGIQDTKILTMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSfditKTDQERTMPVTARQLETLIRLST 623
Cdd:cd17753 224 EKNQRQRPKETKVEPIPQELLRKYIHYAREkVRPKLNQMDMDKVSRVYADLRK----ESMATGSLPITVRHLESIIRISE 299
|
330
....*....|....*....
gi 17562700 624 AIAKARFSKKVEREDTEKA 642
Cdd:cd17753 300 AHAKMHLREYVSEEDVDMA 318
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
118-652 |
2.40e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 285.35 E-value: 2.40e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 118 PRTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFADFT------MLDTAVTNNNYPTEDENKNPLET 191
Cdd:PTZ00111 218 VGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTcehyeyVIQGEVNEPLLCNECNSKYTFEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 192 EFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADL--------------------DLADRVKPGDRVRIIGVFRVLPN 251
Cdd:PTZ00111 298 NHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSglngeiymkdnevinlnlydDLIDSVKTGDRVTVVGILKVTPI 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 252 KQNGVS---SGSFRSIIIINHIQMLSK----EVIPNFE----PQDVKD--VRKISK-SRNP--FELLARSLAPSICGHEE 315
Cdd:PTZ00111 378 RTSTTRrtlKSLYTYFVNVIHVKVINStnanQPEKGLKylgnENDFSDlqVYKILElSRNPmiYRILLDSFAPSIKARNN 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 316 TKKALLCLLLGGMEKILNNG---------SRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVT 386
Cdd:PTZ00111 458 VKIGLLCQLFSGNKNSSDFNkspdacykvDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIK 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 387 -TDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNPF 465
Cdd:PTZ00111 538 fNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKN 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 466 KSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKlhtyrtqgeaDGTVLPMGGgvetiSTINMETKKASSSIY 545
Cdd:PTZ00111 618 KAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK----------DFLLPHMTG-----SGNDEDTYDRSNTMH 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 546 EENTQWAGIQDTKILTMDFMRKYIHLAR-SVQPKLTDEATEYISEVYADIR-------SFDITKTDQE------------ 605
Cdd:PTZ00111 683 VEDESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRqgnfqtsNLDELEHAQEdddddlyyqssg 762
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 17562700 606 -RTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEKAYNLLHFACFK 652
Cdd:PTZ00111 763 tRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQ 810
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
301-646 |
2.01e-74 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 244.38 E-value: 2.01e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVG 380
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 381 LTaaVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPvYG 460
Cdd:cd17760 81 LT--VTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 461 RYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLklhtyrtqgEADGtvlpmgggvetistinmETKKA 540
Cdd:cd17760 158 QYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---------ENKG-----------------EPSKS 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 541 SssiyeentqwagiqdtKILTMDFMRKYIHLARSVQPKLTDEATEYISEVYADIRSFDitKTDQERTmpvTARQLETLIR 620
Cdd:cd17760 212 S----------------KLWSMEKMRTYFCLIKNLRPVLSDEANAILLRYYQLQRQSD--CRNAART---TIRMLESLIR 270
|
330 340
....*....|....*....|....*.
gi 17562700 621 LSTAIAKARFSKKVEREDTEKAYNLL 646
Cdd:cd17760 271 LAEAHARLMFRETVTEEDAITVVSVM 296
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
301-646 |
5.23e-71 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 235.12 E-value: 5.23e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 301 LLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSR--LRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSG 378
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRipIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 379 VGLTAAVTTDPDSGERRLEAGAMVLADRGVVCIDEFDKMSDiDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPV 458
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 459 YGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHvlklhtyrtqgeadgtvlpmgggvetistinmetk 538
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH----------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 539 kasssiyeentqwagiqdtkiltMDFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSfditKTDQERTMPVTARQLET 617
Cdd:cd17759 205 -----------------------HQLLRKYISYARQyVNPVLSKDASEALQEFYLELRK----QNQLADSSPITTRQLES 257
|
330 340
....*....|....*....|....*....
gi 17562700 618 LIRLSTAIAKARFSKKVEREDTEKAYNLL 646
Cdd:cd17759 258 LIRLTEARARLELREEATKEDAEDVIEIM 286
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
119-250 |
1.50e-40 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 144.93 E-value: 1.50e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 119 RTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFADFTMLDTAVTNNNYPtedenkNPLETEFghSVY 198
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPTKCPNPECGNKDP------FKLVHEK--SKF 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 17562700 199 KDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGVFRVLP 250
Cdd:pfam17207 75 VDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
563-646 |
2.51e-24 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 97.23 E-value: 2.51e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 563 DFMRKYIHLARS-VQPKLTDEATEYISEVYADIRSFDITKTDqerTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEK 641
Cdd:pfam17855 1 ELLRKYIAYAREkIKPKLSEEAREKLVDAYVELRKESTGSGS---SIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEE 77
|
....*
gi 17562700 642 AYNLL 646
Cdd:pfam17855 78 AIRLL 82
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
343-482 |
3.22e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 47.29 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 343 NVLLIGDPSVAKSQLLRYVLRMapraitTTGRGSSGVGLTAAVTTD-------PDSGERRLEAGAMVLADR--GVVCIDE 413
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAA------LSNRPVFYVQLTRDTTEEdlfgrrnIDPGGASWVDGPLVRAARegEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17562700 414 FDKMSDIDRTAIHEVMEQGRVTISKAG--IHAKLNARcSVLAAANPVYGRYNPFKSPmenigmqdsLLSRF 482
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGelVKAAPDGF-RLIATMNPLDRGLNELSPA---------LRSRF 135
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
399-457 |
2.27e-05 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 46.37 E-value: 2.27e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17562700 399 GAMVLADRGVVCIDEfdkMSDIDRTAI---HEVMEQGRVTISKAGIHAKLNARCSVLAAANP 457
Cdd:pfam01078 100 GEISLAHNGVLFLDE---LPEFKRRVLeslRQPLEDGEITISRARAKVTFPARFQLVAAMNP 158
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
310-495 |
4.23e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 46.31 E-value: 4.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 310 ICGHEETKKALLCLLLGGmekilnngsrlrgdiNVLLIGDPSVAKSQLLR---YVLRMAPRAITTTgrgssgVGLTAA-V 385
Cdd:COG0714 15 VGQEELIELVLIALLAGG---------------HLLLEGVPGVGKTTLAKalaRALGLPFIRIQFT------PDLLPSdI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 386 T----TDPDSGERRLEAGAmVLAdrGVVCIDEfdkmsdIDRT------AIHEVMEQGRVTIskAGIHAKLNARCSVLAAA 455
Cdd:COG0714 74 LgtyiYDQQTGEFEFRPGP-LFA--NVLLADE------INRAppktqsALLEAMEERQVTI--PGGTYKLPEPFLVIATQ 142
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 17562700 456 NPVygrynpfkspmENIG---MQDSLLSRFdLIFVLLDEHDAD 495
Cdd:COG0714 143 NPI-----------EQEGtypLPEAQLDRF-LLKLYIGYPDAE 173
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
343-488 |
6.08e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 40.98 E-value: 6.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562700 343 NVLLIGDPSVAKSQLLRYVLRMAPRaitttgRGSSGVGLTAAVTTDPDSGE-------RRLEAGAMVLADRGVVCIDEFD 415
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFR------PGAPFLYLNASDLLEGLVVAelfghflVRLLFELAEKAKPGVLFIDEID 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17562700 416 KMSDIDRTAIHEVMEQGRVTIskagihaKLNARCSVLAAANpvygrynpfksPMENIGMQDSLLSRFDLIFVL 488
Cdd:cd00009 95 SLSRGAQNALLRVLETLNDLR-------IDRENVRVIGATN-----------RPLLGDLDRALYDRLDIRIVI 149
|
|
| YifB |
COG0606 |
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ... |
399-457 |
3.34e-03 |
|
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440371 [Multi-domain] Cd Length: 502 Bit Score: 40.79 E-value: 3.34e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17562700 399 GAMVLADRGVVCIDEfdkMSDIDRTAIhEV----MEQGRVTISKAGIHAKLNARCSVLAAANP 457
Cdd:COG0606 290 GEISLAHNGVLFLDE---LPEFSRRVL-EAlrqpLEDGEVTISRANGSVTYPARFQLVAAMNP 348
|
|
| |
