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Conserved domains on  [gi|32567216|ref|NP_506084|]
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Serpentine Receptor, class H [Caenorhabditis elegans]

Protein Classification

serpentine receptor domain-containing protein( domain architecture ID 27798)

serpentine receptor domain-containing protein which belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srh super family cl11665
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 13-314 3.03e-35

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10318:

Pssm-ID: 416353  Cd Length: 302  Bit Score: 129.97  E-value: 3.03e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    13 VYKTLMHTLHILDVPLYLIVIIALFKIKSNIFQTYKYYLIWHTIINVLTEFHSCFLMLPVVHLPYPLLRATGILAEFGFS 92
Cdd:pfam10318   5 FLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSYLGVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    93 GLFLFYVLSAFIIQTSFSIIEMFYFRYKAsVFDYQSRNFTKFVKLFIYSFRVLTILFPGITFgtfFYSIERQEEYKKELA 172
Cdd:pfam10318  85 TPIQFYIGVTSLALVGVSIILLFENRYSI-LFTNKKRITWKKTRVLYLIFNYIIALLFLIPI---YLNIPDQEAAKLKVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   173 MIDPSIP-EVTCYSSVLAAPFSDSVMISTMITwLACIICAFSVIPSTTIYLNSHLRSTKNMSPGVVRMQKMLLSSLIVQT 251
Cdd:pfam10318 161 KKLPCLPpEFFDNPPVFVLAIDSTYFLICIVL-LILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQV 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 32567216   252 FVHGFMLGIPNILFVYTIFFGAHLEVAAYAAFMCLTFHGFLSTIAMIMYTKPIHIAILETFQR 314
Cdd:pfam10318 240 SIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 13-314 3.03e-35

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 129.97  E-value: 3.03e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    13 VYKTLMHTLHILDVPLYLIVIIALFKIKSNIFQTYKYYLIWHTIINVLTEFHSCFLMLPVVHLPYPLLRATGILAEFGFS 92
Cdd:pfam10318   5 FLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSYLGVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    93 GLFLFYVLSAFIIQTSFSIIEMFYFRYKAsVFDYQSRNFTKFVKLFIYSFRVLTILFPGITFgtfFYSIERQEEYKKELA 172
Cdd:pfam10318  85 TPIQFYIGVTSLALVGVSIILLFENRYSI-LFTNKKRITWKKTRVLYLIFNYIIALLFLIPI---YLNIPDQEAAKLKVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   173 MIDPSIP-EVTCYSSVLAAPFSDSVMISTMITwLACIICAFSVIPSTTIYLNSHLRSTKNMSPGVVRMQKMLLSSLIVQT 251
Cdd:pfam10318 161 KKLPCLPpEFFDNPPVFVLAIDSTYFLICIVL-LILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQV 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 32567216   252 FVHGFMLGIPNILFVYTIFFGAHLEVAAYAAFMCLTFHGFLSTIAMIMYTKPIHIAILETFQR 314
Cdd:pfam10318 240 SIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 13-314 3.03e-35

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 129.97  E-value: 3.03e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    13 VYKTLMHTLHILDVPLYLIVIIALFKIKSNIFQTYKYYLIWHTIINVLTEFHSCFLMLPVVHLPYPLLRATGILAEFGFS 92
Cdd:pfam10318   5 FLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSYLGVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    93 GLFLFYVLSAFIIQTSFSIIEMFYFRYKAsVFDYQSRNFTKFVKLFIYSFRVLTILFPGITFgtfFYSIERQEEYKKELA 172
Cdd:pfam10318  85 TPIQFYIGVTSLALVGVSIILLFENRYSI-LFTNKKRITWKKTRVLYLIFNYIIALLFLIPI---YLNIPDQEAAKLKVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   173 MIDPSIP-EVTCYSSVLAAPFSDSVMISTMITwLACIICAFSVIPSTTIYLNSHLRSTKNMSPGVVRMQKMLLSSLIVQT 251
Cdd:pfam10318 161 KKLPCLPpEFFDNPPVFVLAIDSTYFLICIVL-LILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQV 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 32567216   252 FVHGFMLGIPNILFVYTIFFGAHLEVAAYAAFMCLTFHGFLSTIAMIMYTKPIHIAILETFQR 314
Cdd:pfam10318 240 SIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
 17-303 5.99e-11

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 62.18  E-value: 5.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    17 LMHTLHILDVPLYLIVIIALFKI--KSNIFQTYKYYLIWHTIINVLTEFHSCFLMLPVVHLPYPLLRATGILAE-FGFSG 93
Cdd:pfam10327  11 LILYYHIIGTISLILNLLGIYLIifKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNGFLATvFGISS 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    94 LFLFYVLSAFIIQTSFSIIEMFYFRYKASVfdyQSRNFTKFVKLFIYSFRVLTILFPGITFGTFFYSierQEEYKKELAM 173
Cdd:pfam10327  91 HYLMTIFVFLLSFQLESLLLCFVRKHQAIA---KILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQS---GLSREEQLEY 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   174 IDPSIPEvtCYSSVLAAP-FSDSVMISTMITWLACIICAFSVIPSTTIYLNSHL-----RSTKNMSPGVVRMQKMLLSSL 247
Cdd:pfam10327 165 VKENYPE--YLSQFSSLPnFAIYDYNPWLIVFGILAIFGGSLSFLILVYLTVDMfrmlkRLRKKISAQTYQKHRAALRSL 242

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 32567216   248 IVQtFVHGFMLGIPNILFVYTIFFGA-HLEVAAYAAFMCLTFHGFLSTIAMIMYTKP 303
Cdd:pfam10327 243 IAQ-FATSPVCILPPFAFVVVVLFPIeYSQEISEILLAIFSTHSSVNSIVLILTTPP 298
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 23-303 1.10e-07

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 52.55  E-value: 1.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216    23 ILDVPLYLIVIIALFKIKSNIFQTYKYYLIWHTIINVLTEFHSCFLMLPVVHLPYPL-LRATGILAEFG-FSGLFLFYVL 100
Cdd:pfam10317  10 ILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMaLISYGPCKYFGpWFCYSGYSLL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   101 SAFIIQTSFSIIEMFYFRYKASVFDYQSRNFTKFVKLFIYSFRVLTILFPGITFgTFFYSIERQEeyKKELAMIDPSIPE 180
Cdd:pfam10317  90 QHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSP-TDFLPVEALT--KELHPNYNLTDYT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32567216   181 VTCYSSVLAAPFSDSVMISTMITWLACIICaFSVIPSTTIYLNShlrSTKNMSPGVVRMQKMLLSSLIVQTFVHGFMLGI 260
Cdd:pfam10317 167 VTGFSDLQSFPALINTLIMTIPVFPIPIII-LILRRKILKLLNS---NSVNMSPTTKAQHRQLIKGLTIQALLPLFSYIP 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 32567216   261 PNILFVYTIFFGAHLEVAAYAAFMCLTFHGFLSTIAMIMYTKP 303
Cdd:pfam10317 243 GVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTP 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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