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Conserved domains on  [gi|17560458|ref|NP_505777|]
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Transmembrane protein 70 homolog, mitochondrial [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMEM70 super family cl06160
TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 ...
 73-170 1.57e-06

TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 protein family. TMEM70 is a family of proteins essential for assembly of the mitochondrial proton-transporting ATP synthase complex within the inner mitochondrial membrane. TMEM70 functions in the assembly of complexes I and V.


The actual alignment was detected with superfamily member pfam06979:

Pssm-ID: 462058  Cd Length: 151  Bit Score: 46.44  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560458    73 VKGAKILSLSSSLAGVVMVPVLSSYLwEAAAERPSMMMFAIVANTFLVLlsfTPLLLHFLAKRFPIDIFYNNDKKVFTTV 152
Cdd:pfam06979  14 FRGLKIFSLSQSIFWLYLAPFAYTKL-INLGSNKLRVGLTGICGFFGFV---TPGLLHLFTKRYVTRLYLDKGGDTVTAT 89

                          90
                  ....*....|....*...
gi 17560458   153 HYNFLMQKQALRFSASEV 170
Cdd:pfam06979  90 TYNPFGREKKTEFPLEDV 107
 
Name Accession Description Interval E-value
TMEM70 pfam06979
TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 ...
 73-170 1.57e-06

TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 protein family. TMEM70 is a family of proteins essential for assembly of the mitochondrial proton-transporting ATP synthase complex within the inner mitochondrial membrane. TMEM70 functions in the assembly of complexes I and V.


Pssm-ID: 462058  Cd Length: 151  Bit Score: 46.44  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560458    73 VKGAKILSLSSSLAGVVMVPVLSSYLwEAAAERPSMMMFAIVANTFLVLlsfTPLLLHFLAKRFPIDIFYNNDKKVFTTV 152
Cdd:pfam06979  14 FRGLKIFSLSQSIFWLYLAPFAYTKL-INLGSNKLRVGLTGICGFFGFV---TPGLLHLFTKRYVTRLYLDKGGDTVTAT 89

                          90
                  ....*....|....*...
gi 17560458   153 HYNFLMQKQALRFSASEV 170
Cdd:pfam06979  90 TYNPFGREKKTEFPLEDV 107
 
Name Accession Description Interval E-value
TMEM70 pfam06979
TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 ...
 73-170 1.57e-06

TMEM70/TMEM186/TMEM223 protein family; This entry represents the TMEM70/TMEM186/TMEM223 protein family. TMEM70 is a family of proteins essential for assembly of the mitochondrial proton-transporting ATP synthase complex within the inner mitochondrial membrane. TMEM70 functions in the assembly of complexes I and V.


Pssm-ID: 462058  Cd Length: 151  Bit Score: 46.44  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17560458    73 VKGAKILSLSSSLAGVVMVPVLSSYLwEAAAERPSMMMFAIVANTFLVLlsfTPLLLHFLAKRFPIDIFYNNDKKVFTTV 152
Cdd:pfam06979  14 FRGLKIFSLSQSIFWLYLAPFAYTKL-INLGSNKLRVGLTGICGFFGFV---TPGLLHLFTKRYVTRLYLDKGGDTVTAT 89

                          90
                  ....*....|....*...
gi 17560458   153 HYNFLMQKQALRFSASEV 170
Cdd:pfam06979  90 TYNPFGREKKTEFPLEDV 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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