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Conserved domains on  [gi|17563466|ref|NP_503769|]
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Serpentine Receptor, class J [Caenorhabditis elegans]

Protein Classification

class J serpentine receptor( domain architecture ID 10563403)

class J serpentine receptor (Srj) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
1-312 1.25e-156

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 370974  Cd Length: 310  Bit Score: 441.68  E-value: 1.25e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466     1 MFEDWIYKYLPRTFCALTFLVNPIFIYLIFSEKSSKFGNYRYLLLYFAIFNLLYSIMNVLVPLDIHTFGYSFFLIVRHGW 80
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    81 FQtegNSSQLNFHMLIARTSSVSSSYAVLMSHFIYRYLVISDSSLTRHHF-HWFMTGSVYMLFAYFSVWHATCYFPGKAN 159
Cdd:pfam10319  81 FF---EYSELGQHALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFrPWGILISILFFLFHGSVWTAICYFLLRAN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   160 SELLEYVSEDFQENFGMDSRNLNVIGTLFSVGSHETTLRAWTAMSIWSTISIASIITFFVMAGLVMRKLRKMTVRTSQKT 239
Cdd:pfam10319 158 DEIRDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSKKT 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17563466   240 SQFQFELLRALIVQTVTPICFSFSPCLLCWYSPIFGIKLDRWLNYLEVTALGLFSFMDPIAIILCLPIFRYRI 312
Cdd:pfam10319 238 KRLQKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
 
Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
1-312 1.25e-156

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 441.68  E-value: 1.25e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466     1 MFEDWIYKYLPRTFCALTFLVNPIFIYLIFSEKSSKFGNYRYLLLYFAIFNLLYSIMNVLVPLDIHTFGYSFFLIVRHGW 80
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    81 FQtegNSSQLNFHMLIARTSSVSSSYAVLMSHFIYRYLVISDSSLTRHHF-HWFMTGSVYMLFAYFSVWHATCYFPGKAN 159
Cdd:pfam10319  81 FF---EYSELGQHALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFrPWGILISILFFLFHGSVWTAICYFLLRAN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   160 SELLEYVSEDFQENFGMDSRNLNVIGTLFSVGSHETTLRAWTAMSIWSTISIASIITFFVMAGLVMRKLRKMTVRTSQKT 239
Cdd:pfam10319 158 DEIRDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSKKT 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17563466   240 SQFQFELLRALIVQTVTPICFSFSPCLLCWYSPIFGIKLDRWLNYLEVTALGLFSFMDPIAIILCLPIFRYRI 312
Cdd:pfam10319 238 KRLQKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
 
Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
1-312 1.25e-156

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 441.68  E-value: 1.25e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466     1 MFEDWIYKYLPRTFCALTFLVNPIFIYLIFSEKSSKFGNYRYLLLYFAIFNLLYSIMNVLVPLDIHTFGYSFFLIVRHGW 80
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    81 FQtegNSSQLNFHMLIARTSSVSSSYAVLMSHFIYRYLVISDSSLTRHHF-HWFMTGSVYMLFAYFSVWHATCYFPGKAN 159
Cdd:pfam10319  81 FF---EYSELGQHALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFrPWGILISILFFLFHGSVWTAICYFLLRAN 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   160 SELLEYVSEDFQENFGMDSRNLNVIGTLFSVGSHETTLRAWTAMSIWSTISIASIITFFVMAGLVMRKLRKMTVRTSQKT 239
Cdd:pfam10319 158 DEIRDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSKKT 237
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17563466   240 SQFQFELLRALIVQTVTPICFSFSPCLLCWYSPIFGIKLDRWLNYLEVTALGLFSFMDPIAIILCLPIFRYRI 312
Cdd:pfam10319 238 KRLQKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
15-313 9.61e-43

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 150.30  E-value: 9.61e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    15 CALTFLVNPIFIYLIFSEKSSKFGNYRYLLLYFAIFNLLYSIMNVLVPLDIHTFGYSFFLIVRHGWFqtegnssqlNFHM 94
Cdd:pfam10326   9 FFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDL---------GLSK 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    95 LIARTSSV--SSSYAVLMS----HFIYRYLVISDSSLTRHHFHWFMTGSVYMLFAYFSVWHATCYFPGKANSELLEYVSE 168
Cdd:pfam10326  80 SVGQILLAlyCGFYGVSISllavQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLRE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   169 DFQENFGMDSRNLNVIGTLF----SVGSHETTLRAWTAMSIWSTISIASIITFFVMAGLVMRKLRKMTVRTSQKTSQFQF 244
Cdd:pfam10326 160 ELLENYNLDIDEVAYVGPVYyptdENGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQK 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17563466   245 ELLRALIVQTVTPICFSFSPCLLCWYSPIFGIKLDRWLNYLEVTaLGLFSFMDPIAIILCLPIFRYRIF 313
Cdd:pfam10326 240 QLFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITAT-IALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
14-312 5.04e-09

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 56.79  E-value: 5.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    14 FCALTFLVNPIFIYLIFSEKSSKFGNYRYLLLYFAIFNLLYSIMNVLVPLDIHTFGYSFFLIVrHGWFQTEGNSSQLNFH 93
Cdd:pfam10317   8 FFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALIS-YGPCKYFGPWFCYSGY 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    94 MLIArTSSVSSSYAVLMShFIYRYLVISDSSLTRHhfhwfMTGSVYMLFAYFSVWHATCYFPGKANSELLEYVSEDFQEN 173
Cdd:pfam10317  87 SLLQ-HFLLHSGWSLLLT-FYYRYYILKHVDPKRK-----KLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   174 FGMDsrNLNVIGtlfsvgshetTLRAWTAMSIWSTISIASIITFFVMAGLVMRK-----LRKMTVRTSQKTSQFQFELLR 248
Cdd:pfam10317 160 YNLT--DYTVTG----------FSDLQSFPALINTLIMTIPVFPIPIIILILRRkilklLNSNSVNMSPTTKAQHRQLIK 227
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563466   249 ALIVQTVTPICFSFSPCLLCWYSPIFGIKLDrwlnYLEVTALGLFSFM---DPIAIILCLPIFRYRI 312
Cdd:pfam10317 228 GLTIQALLPLFSYIPGVTLYLLSQLTGTEFL----ILEYFIFVLPALPpllDPLITIYFVTPYRRAI 290
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
19-267 4.47e-06

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 47.54  E-value: 4.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    19 FLVNPIFIYLIFSeKSSKFGNYRYLLLYFAIFNLLYSI-MNVLVPldihtfGYSFFLIV---RHGWFQTEGNSSQlnfHM 94
Cdd:pfam10327  23 LILNLLGIYLIIF-KSGKIDNFRYYLLYFQISCTLTDIhLTFLMQ------PIPLFPIIagyCNGFLATVFGISS---HY 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466    95 LIA-RTSSVSSSYAVLMSHFIYRYLVISdSSLTRHHFHWFMTGSVYMLFAYFSV-WHATCYFPGKANSELLEYVSEDFQE 172
Cdd:pfam10327  93 LMTiFVFLLSFQLESLLLCFVRKHQAIA-KILSKHVIPKWLYIFLYILCHIFPFlTAFLFYQSGLSREEQLEYVKENYPE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563466   173 NFGMDSRNLNvigtlFSVGSHETTLRAWTAMSIWSTISIASIITFFVMAglVMRKLRKMTVRTSQKTSQFQFELLRALIV 252
Cdd:pfam10327 172 YLSQFSSLPN-----FAIYDYNPWLIVFGILAIFGGSLSFLILVYLTVD--MFRMLKRLRKKISAQTYQKHRAALRSLIA 244
                         250
                  ....*....|....*
gi 17563466   253 QTVTPICFSFSPCLL 267
Cdd:pfam10327 245 QFATSPVCILPPFAF 259
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
201-275 4.73e-04

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 41.37  E-value: 4.73e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17563466   201 TAMSIWSTISIASIITFFVMAGLVMRKLRKMTVrtSQKTSQFQFELLRALIVQTVTPICFSFSPCLLCWYSPIFG 275
Cdd:pfam10318 188 ICIVLLILILIIQILFFVFLTIYYLFKSVKSSL--SKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFG 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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