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Conserved domains on  [gi|71992260|ref|NP_503278|]
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glucuronosyltransferase [Caenorhabditis elegans]

Protein Classification

glycosyltransferase( domain architecture ID 10133209)

glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  12691742|16037492|10521532
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 20-464 1.68e-66

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


:

Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 220.50  E-value: 1.68e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  20 NYLVVSPAfGHSHSTFMGKLADALTEAGHNVTVLSIIvsskfRNISYTKLTKDIVVVETTNEQDQQAENMENNDFSRYWT 99
Cdd:cd03784   2 RILFVPFP-GQGHVNPMLPLAKALAARGHEVTVATPP-----FNFADLVEAAGLTFVPVGDDPDELELDSETNLGPDSLL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 100 QEGTlletipsylMFTKMSDHgyetfrnhALPQMEYLKSHRPRYDAVFFESYLHTGKAIQEYLEIPVFLPVTS-----LT 174
Cdd:cd03784  76 ELLR---------RLLKAADE--------LLDDLLAALRSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGpatllSA 138

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 175 HDYRLAELIGEPVSPSYLSGYFTNFGNIMNFQERVINtlsyylaqilisspnwktlQDPSKDLLVESEYYRAPYVFINSN 254
Cdd:cd03784 139 YLHPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLG-------------------LPPFSLVLLLLRLVPPLYVIGPTF 199

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 255 PYIDFPRPLLSKTIEIGGItvdaDALKSEKVDETWNNILKRRPH-NVLISFGTMFKsiHMPDSYKNNMVKVMKSFkNVTF 333
Cdd:cd03784 200 PSLPPDRPRLPSVLGGLRI----VPKNGPLPDELWEWLDKQPPRsVVYVSFGSMVR--DLPEELLELIAEALASL-GQRF 272

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 334 IWKYESEETSF-ANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGS 412
Cdd:cd03784 273 LWVVGPDPLGGlERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAG 352

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|...
gi 71992260 413 IEISKFNLESyNTLRSALHSILFDESYAENAEKLAKKLEF-QPAKPKELFVRH 464
Cdd:cd03784 353 VELDKDELTA-EELAKAVREVLEDESYRRAAELLAELREEdGAPSAADVVERL 404
 
Name Accession Description Interval E-value
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 20-464 1.68e-66

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 220.50  E-value: 1.68e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  20 NYLVVSPAfGHSHSTFMGKLADALTEAGHNVTVLSIIvsskfRNISYTKLTKDIVVVETTNEQDQQAENMENNDFSRYWT 99
Cdd:cd03784   2 RILFVPFP-GQGHVNPMLPLAKALAARGHEVTVATPP-----FNFADLVEAAGLTFVPVGDDPDELELDSETNLGPDSLL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 100 QEGTlletipsylMFTKMSDHgyetfrnhALPQMEYLKSHRPRYDAVFFESYLHTGKAIQEYLEIPVFLPVTS-----LT 174
Cdd:cd03784  76 ELLR---------RLLKAADE--------LLDDLLAALRSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGpatllSA 138

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 175 HDYRLAELIGEPVSPSYLSGYFTNFGNIMNFQERVINtlsyylaqilisspnwktlQDPSKDLLVESEYYRAPYVFINSN 254
Cdd:cd03784 139 YLHPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLG-------------------LPPFSLVLLLLRLVPPLYVIGPTF 199

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 255 PYIDFPRPLLSKTIEIGGItvdaDALKSEKVDETWNNILKRRPH-NVLISFGTMFKsiHMPDSYKNNMVKVMKSFkNVTF 333
Cdd:cd03784 200 PSLPPDRPRLPSVLGGLRI----VPKNGPLPDELWEWLDKQPPRsVVYVSFGSMVR--DLPEELLELIAEALASL-GQRF 272

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 334 IWKYESEETSF-ANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGS 412
Cdd:cd03784 273 LWVVGPDPLGGlERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAG 352

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|...
gi 71992260 413 IEISKFNLESyNTLRSALHSILFDESYAENAEKLAKKLEF-QPAKPKELFVRH 464
Cdd:cd03784 353 VELDKDELTA-EELAKAVREVLEDESYRRAAELLAELREEdGAPSAADVVERL 404
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
22-495 3.66e-31

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 126.37  E-value: 3.66e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260    22 LVVSPAFghSHSTFMGKLADALTEAGHNVTVL----SIIV----SSKFRNISY-TKLTKDIVVVETTNEQDQQAENMEnn 92
Cdd:pfam00201   4 LVWPMDG--SHWMNMKGILEELVQRGHEVTVLrpsaSISIgpgkPSNLKFETYpTSATKEELENPFPKRQMQWFEEAS-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260    93 dFSRYWTQEGTLLETIPSYLMFTKmsdhgyETFRNHALpqMEYLKShrPRYDAVFFESYLHTGKAIQEYLEIPvFLPVTS 172
Cdd:pfam00201  80 -FGTVWSYFSALQEYSDGYRVTCK------ELVGNKKL--MTKLQE--SSFDVVLADPVWPCGELLAELLHIP-TVYSLR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   173 LTHDYRLAELIGE-PVSPSYLSGYFTNFGNIMNFQERV----INTLSYYLAQILISSpnW-----KTLQDPSKDL----L 238
Cdd:pfam00201 148 FVPGYAAEKVSGGlPSPPSYVPVILSDLSDHMTFMERVknmlIMLYFDFWFQCFPRK--WdqfasEVLGRPVTLPelmsK 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   239 VESEYYRAPYVFinsnpyiDFPRPLLSKTIEIGGIT-VDADALKSEkvdeTWNNILKRRPHNVLI-SFGTMFKSihMPDS 316
Cdd:pfam00201 226 ASVWLIRSYWDL-------EFPRPLLPNMDFIGGLHcKPAKPLPQE----MEAFVQSSGEHGVVVfSLGSMVSN--IPEE 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   317 YKNNMVKVMKSFKNvTFIWKYEseETSFANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLF 396
Cdd:pfam00201 293 KANAIASALAQIPQ-KVLWRFD--GTKPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLF 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   397 ADQVRNSKMLSRHNGSIEISKFNLESYNtLRSALHSILFDESYAENAEKLAKKLEFQPAKPKELFVRHAEFAARFGEQPA 476
Cdd:pfam00201 370 GDQMDNAKHMEAKGAAVTLNVLTMTSED-LLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKH 448

                         490
                  ....*....|....*....
gi 71992260   477 LDCNLRTMGFATYHLLDVV 495
Cdd:pfam00201 449 LRPAAHDLTWYQYHSLDVI 467
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
242-451 3.81e-20

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 90.30  E-value: 3.81e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 242 EYYRAPYVFINSnPYIDFPRPLLSKTIE-IGGITVDADAlksekVDETWNNILKRRPHnVLISFGTMFksIHMPDSYKnn 320
Cdd:COG1819  71 EALGIPVVSLTP-PELEYPRPPDPANVRfVGPLLPDGPA-----ELPPWLEEDAGRPL-VYVTLGTSA--NDRADLLR-- 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 321 mvKVMKSFK--NVTFIW---KYESEEtsFANGAENIIFKKWTPQTALLAdsRLSAFFTHGGLGSVNELSYLGKPALLCPL 395
Cdd:COG1819 140 --AVLEALAdlGVRVVVttgGLDPAE--LGPLPDNVRVVDYVPQDALLP--RADAVVHHGGAGTTAEALRAGVPQVVVPF 213

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260 396 FADQVRNSKMLSRHNGSIEISKFNLESyNTLRSALHSILFDESYAENAEKLAKKLE 451
Cdd:COG1819 214 GGDQPLNAARVERLGAGLALPPRRLTA-EALRAALRRLLADPSYRERAARLAAEIR 268
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 14-501 2.95e-15

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 78.08  E-value: 2.95e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   14 SNISGFNYLVV--SPAFGHsHSTFmGKLADALTEAGHNVTVlsiiVSSKFRNISYTKLTKDIVVVETTNEQDQQAENMEN 91
Cdd:PHA03392  16 SGVRAARILAVfpTPAYSH-HSVF-KVYVEALAERGHNVTV----IKPTLRVYYASHLCGNITEIDASLSVEYFKKLVKS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   92 NDFSRYW---TQEGTLleTIPSYL----MFTKMSDHgyETFRNHalpqmeyLKSHRPRYDAVFFESYLhtgkaiqeylEI 164
Cdd:PHA03392  90 SAVFRKRgvvADSSTV--TADNYMglvrMISDQFDL--PNVKNL-------IANKNNKFDLLVTEAFL----------DY 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  165 P-VF------LPVTSLTHDYRLAE---LIGepvSPSYLSGYFTNFGNIMNFQERVINTLSYYLAQILISSpNWKTLQDPS 234
Cdd:PHA03392 149 PlVFshlfgdAPVIQISSGYGLAEnfeTMG---AVSRHPVYYPNLWRSKFGNLNVWETINEIYTELRLYN-EFSLLADEQ 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  235 KDLLVESEYYRAPYV----------FINSNPYIDFPRPLLSKTIEIGGITVDAdaLKSEKVDETWNNILKRRPHNVL-IS 303
Cdd:PHA03392 225 NKLLKQQFGPDTPTIrelrnrvqllFVNVHPVFDNNRPVPPSVQYLGGLHLHK--KPPQPLDDYLEEFLNNSTNGVVyVS 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  304 FGTMFKSIHMPDSYKNNMVKVMKSFkNVTFIWKYESEETSFANGAeNIIFKKWTPQTALLADSRLSAFFTHGGLGSVNEL 383
Cdd:PHA03392 303 FGSSIDTNDMDNEFLQMLLRTFKKL-PYNVLWKYDGEVEAINLPA-NVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEA 380

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  384 SYLGKPALLCPLFADQVRNSKMLSRHNGSIEISKFNLESYNTLRsALHSILFDESYAENAEKLAKKLEFQPAKPKELFVR 463
Cdd:PHA03392 381 IDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVL-AIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIW 459

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 71992260  464 HAEFAARFGEQPALdcnLRT----MGFATYHLLDVVVCLTSF 501
Cdd:PHA03392 460 YTEHVIRNKHGNTS---LKTkaanVSYSDYFMSYILVPLVTF 498
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 284-446 4.89e-11

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 64.71  E-value: 4.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   284 KVDETWNNILKRRPhNVLISFGTMFKSihMPDSYKNNMVKVMKSFKNVTFIWKYESEETSFANGAENIIFKKWTPQTALL 363
Cdd:TIGR01426 213 KEDGSWERPGDGRP-VVLISLGTVFNN--QPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLGELPPNVEVRQWVPQLEIL 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   364 adSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGSIEISKFNLESyNTLRSALHSILFDESYAENA 443
Cdd:TIGR01426 290 --KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTA-EKLREAVLAVLSDPRYAERL 366


                  ...
gi 71992260   444 EKL 446
Cdd:TIGR01426 367 RKM 369
 
Name Accession Description Interval E-value
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 20-464 1.68e-66

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 220.50  E-value: 1.68e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  20 NYLVVSPAfGHSHSTFMGKLADALTEAGHNVTVLSIIvsskfRNISYTKLTKDIVVVETTNEQDQQAENMENNDFSRYWT 99
Cdd:cd03784   2 RILFVPFP-GQGHVNPMLPLAKALAARGHEVTVATPP-----FNFADLVEAAGLTFVPVGDDPDELELDSETNLGPDSLL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 100 QEGTlletipsylMFTKMSDHgyetfrnhALPQMEYLKSHRPRYDAVFFESYLHTGKAIQEYLEIPVFLPVTS-----LT 174
Cdd:cd03784  76 ELLR---------RLLKAADE--------LLDDLLAALRSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGpatllSA 138

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 175 HDYRLAELIGEPVSPSYLSGYFTNFGNIMNFQERVINtlsyylaqilisspnwktlQDPSKDLLVESEYYRAPYVFINSN 254
Cdd:cd03784 139 YLHPFGVLNLLLSSLLEPELFLDPLLEVLDRLRERLG-------------------LPPFSLVLLLLRLVPPLYVIGPTF 199

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 255 PYIDFPRPLLSKTIEIGGItvdaDALKSEKVDETWNNILKRRPH-NVLISFGTMFKsiHMPDSYKNNMVKVMKSFkNVTF 333
Cdd:cd03784 200 PSLPPDRPRLPSVLGGLRI----VPKNGPLPDELWEWLDKQPPRsVVYVSFGSMVR--DLPEELLELIAEALASL-GQRF 272

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 334 IWKYESEETSF-ANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGS 412
Cdd:cd03784 273 LWVVGPDPLGGlERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAG 352

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|...
gi 71992260 413 IEISKFNLESyNTLRSALHSILFDESYAENAEKLAKKLEF-QPAKPKELFVRH 464
Cdd:cd03784 353 VELDKDELTA-EELAKAVREVLEDESYRRAAELLAELREEdGAPSAADVVERL 404
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
22-495 3.66e-31

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 126.37  E-value: 3.66e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260    22 LVVSPAFghSHSTFMGKLADALTEAGHNVTVL----SIIV----SSKFRNISY-TKLTKDIVVVETTNEQDQQAENMEnn 92
Cdd:pfam00201   4 LVWPMDG--SHWMNMKGILEELVQRGHEVTVLrpsaSISIgpgkPSNLKFETYpTSATKEELENPFPKRQMQWFEEAS-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260    93 dFSRYWTQEGTLLETIPSYLMFTKmsdhgyETFRNHALpqMEYLKShrPRYDAVFFESYLHTGKAIQEYLEIPvFLPVTS 172
Cdd:pfam00201  80 -FGTVWSYFSALQEYSDGYRVTCK------ELVGNKKL--MTKLQE--SSFDVVLADPVWPCGELLAELLHIP-TVYSLR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   173 LTHDYRLAELIGE-PVSPSYLSGYFTNFGNIMNFQERV----INTLSYYLAQILISSpnW-----KTLQDPSKDL----L 238
Cdd:pfam00201 148 FVPGYAAEKVSGGlPSPPSYVPVILSDLSDHMTFMERVknmlIMLYFDFWFQCFPRK--WdqfasEVLGRPVTLPelmsK 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   239 VESEYYRAPYVFinsnpyiDFPRPLLSKTIEIGGIT-VDADALKSEkvdeTWNNILKRRPHNVLI-SFGTMFKSihMPDS 316
Cdd:pfam00201 226 ASVWLIRSYWDL-------EFPRPLLPNMDFIGGLHcKPAKPLPQE----MEAFVQSSGEHGVVVfSLGSMVSN--IPEE 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   317 YKNNMVKVMKSFKNvTFIWKYEseETSFANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLF 396
Cdd:pfam00201 293 KANAIASALAQIPQ-KVLWRFD--GTKPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLF 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   397 ADQVRNSKMLSRHNGSIEISKFNLESYNtLRSALHSILFDESYAENAEKLAKKLEFQPAKPKELFVRHAEFAARFGEQPA 476
Cdd:pfam00201 370 GDQMDNAKHMEAKGAAVTLNVLTMTSED-LLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKH 448

                         490
                  ....*....|....*....
gi 71992260   477 LDCNLRTMGFATYHLLDVV 495
Cdd:pfam00201 449 LRPAAHDLTWYQYHSLDVI 467
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
242-451 3.81e-20

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 90.30  E-value: 3.81e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 242 EYYRAPYVFINSnPYIDFPRPLLSKTIE-IGGITVDADAlksekVDETWNNILKRRPHnVLISFGTMFksIHMPDSYKnn 320
Cdd:COG1819  71 EALGIPVVSLTP-PELEYPRPPDPANVRfVGPLLPDGPA-----ELPPWLEEDAGRPL-VYVTLGTSA--NDRADLLR-- 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 321 mvKVMKSFK--NVTFIW---KYESEEtsFANGAENIIFKKWTPQTALLAdsRLSAFFTHGGLGSVNELSYLGKPALLCPL 395
Cdd:COG1819 140 --AVLEALAdlGVRVVVttgGLDPAE--LGPLPDNVRVVDYVPQDALLP--RADAVVHHGGAGTTAEALRAGVPQVVVPF 213

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260 396 FADQVRNSKMLSRHNGSIEISKFNLESyNTLRSALHSILFDESYAENAEKLAKKLE 451
Cdd:COG1819 214 GGDQPLNAARVERLGAGLALPPRRLTA-EALRAALRRLLADPSYRERAARLAAEIR 268
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 14-501 2.95e-15

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 78.08  E-value: 2.95e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   14 SNISGFNYLVV--SPAFGHsHSTFmGKLADALTEAGHNVTVlsiiVSSKFRNISYTKLTKDIVVVETTNEQDQQAENMEN 91
Cdd:PHA03392  16 SGVRAARILAVfpTPAYSH-HSVF-KVYVEALAERGHNVTV----IKPTLRVYYASHLCGNITEIDASLSVEYFKKLVKS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   92 NDFSRYW---TQEGTLleTIPSYL----MFTKMSDHgyETFRNHalpqmeyLKSHRPRYDAVFFESYLhtgkaiqeylEI 164
Cdd:PHA03392  90 SAVFRKRgvvADSSTV--TADNYMglvrMISDQFDL--PNVKNL-------IANKNNKFDLLVTEAFL----------DY 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  165 P-VF------LPVTSLTHDYRLAE---LIGepvSPSYLSGYFTNFGNIMNFQERVINTLSYYLAQILISSpNWKTLQDPS 234
Cdd:PHA03392 149 PlVFshlfgdAPVIQISSGYGLAEnfeTMG---AVSRHPVYYPNLWRSKFGNLNVWETINEIYTELRLYN-EFSLLADEQ 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  235 KDLLVESEYYRAPYV----------FINSNPYIDFPRPLLSKTIEIGGITVDAdaLKSEKVDETWNNILKRRPHNVL-IS 303
Cdd:PHA03392 225 NKLLKQQFGPDTPTIrelrnrvqllFVNVHPVFDNNRPVPPSVQYLGGLHLHK--KPPQPLDDYLEEFLNNSTNGVVyVS 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  304 FGTMFKSIHMPDSYKNNMVKVMKSFkNVTFIWKYESEETSFANGAeNIIFKKWTPQTALLADSRLSAFFTHGGLGSVNEL 383
Cdd:PHA03392 303 FGSSIDTNDMDNEFLQMLLRTFKKL-PYNVLWKYDGEVEAINLPA-NVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEA 380

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  384 SYLGKPALLCPLFADQVRNSKMLSRHNGSIEISKFNLESYNTLRsALHSILFDESYAENAEKLAKKLEFQPAKPKELFVR 463
Cdd:PHA03392 381 IDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVL-AIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIW 459

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|..
gi 71992260  464 HAEFAARFGEQPALdcnLRT----MGFATYHLLDVVVCLTSF 501
Cdd:PHA03392 460 YTEHVIRNKHGNTS---LKTkaanVSYSDYFMSYILVPLVTF 498
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 284-446 4.89e-11

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 64.71  E-value: 4.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   284 KVDETWNNILKRRPhNVLISFGTMFKSihMPDSYKNNMVKVMKSFKNVTFIWKYESEETSFANGAENIIFKKWTPQTALL 363
Cdd:TIGR01426 213 KEDGSWERPGDGRP-VVLISLGTVFNN--QPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLGELPPNVEVRQWVPQLEIL 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   364 adSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGSIEISKFNLESyNTLRSALHSILFDESYAENA 443
Cdd:TIGR01426 290 --KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTA-EKLREAVLAVLSDPRYAERL 366


                  ...
gi 71992260   444 EKL 446
Cdd:TIGR01426 367 RKM 369
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 243-406 2.05e-08

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 56.58  E-value: 2.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  243 YYRAPYVFINSNPYIDF-PRPLLSKT---IEIG----------GITVDAD---ALKSEKVDETWNNILKRRPHN--VLIS 303
Cdd:PLN02173 191 FDKADFVLVNSFHDLDLhENELLSKVcpvLTIGptvpsmyldqQIKSDNDydlNLFDLKEAALCTDWLDKRPQGsvVYIA 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  304 FGTMFKSIHMpdsyknNMVKVMKSFKNVTFIWKYE-SEETSFANGAENIIFK------KWTPQTALLADSRLSAFFTHGG 376
Cdd:PLN02173 271 FGSMAKLSSE------QMEEIASAISNFSYLWVVRaSEESKLPPGFLETVDKdkslvlKWSPQLQVLSNKAIGCFMTHCG 344

                        170       180       190
                 ....*....|....*....|....*....|
gi 71992260  377 LGSVNELSYLGKPALLCPLFADQVRNSKML 406
Cdd:PLN02173 345 WNSTMEGLSLGVPMVAMPQWTDQPMNAKYI 374
PLN02210 PLN02210
UDP-glucosyl transferase
 274-406 2.77e-08

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 56.20  E-value: 2.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  274 TVDADALKSEKVDETWNNILKR--RPHNVLISFGTMFKSIhmpdsyKNNMVKVMKSFKN--VTFIWKYESEETsfangAE 349
Cdd:PLN02210 244 TLDGKNLDMCKSDDCCMEWLDKqaRSSVVYISFGSMLESL------ENQVETIAKALKNrgVPFLWVIRPKEK-----AQ 312

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71992260  350 NI------------IFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKML 406
Cdd:PLN02210 313 NVqvlqemvkegqgVVLEWSPQEKILSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLL 381
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 189-445 3.06e-06

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 49.67  E-value: 3.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  189 PSYLSGYFTNFGNIMNFQErvintlsyyLAQILISSPNWKTLQDPSKDLlvESEyyrapyvFINSNPYIDFPR--PLLSK 266
Cdd:PLN02152 169 PSFLSPSNTNKAAQAVYQE---------LMEFLKEESNPKILVNTFDSL--EPE-------FLTAIPNIEMVAvgPLLPA 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  267 TIEIGGITVDADALKSEKVDETWNNILKRRPHNVLISFGTMfksIHMPDSYKNNMVKVMKSFKNvTFIW----------K 336
Cdd:PLN02152 231 EIFTGSESGKDLSVRDQSSSYTLWLDSKTESSVIYVSFGTM---VELSKKQIEELARALIEGKR-PFLWvitdklnreaK 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  337 YESEE-------TSFANGAENI-IFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLS- 407
Cdd:PLN02152 307 IEGEEeteiekiAGFRHELEEVgMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLEe 386

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 71992260  408 --RHNGSIEISKFNLESYNTLRSALHSILFDESYA--ENAEK 445
Cdd:PLN02152 387 iwKTGVRVRENSEGLVERGEIRRCLEAVMEEKSVElrESAEK 428
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 331-406 3.12e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 49.87  E-value: 3.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  331 VTFIW------KYESEETSFANGAEN------IIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFAD 398
Cdd:PLN02863 313 VHFIWcvkepvNEESDYSNIPSGFEDrvagrgLVIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAAD 392


                 ....*...
gi 71992260  399 QVRNSKML 406
Cdd:PLN02863 393 QFVNASLL 400
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 337-449 1.16e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 45.78  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260   337 YESEETSFANGAENIIFKKWTPQ-TALLADSRLSafFTHGGLGSVNELSYLGKPALLCPL----FADQVRNSKMLSRHNG 411
Cdd:pfam04101  42 LEEVKIDYAELGINYEVFPFIDNmAEYIKAADLV--ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGA 119

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 71992260   412 SIEISKFNLESYNTLRSALHSILFDESYAENAEKLAKK 449
Cdd:pfam04101 120 ALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASKAS 157
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 331-405 1.67e-05

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 47.31  E-value: 1.67e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260  331 VTFIWKYESEETSFANGAENI-IFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKM 405
Cdd:PLN02448 304 VRFLWVARGEASRLKEICGDMgLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSKL 379
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 373-448 4.26e-05

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 45.89  E-value: 4.26e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 373 THGGLGSVNELSYLGKPALLCPL-FA---DQVRNSKMLSRHNGSIEI--SKFNLESyntLRSALHSILFD----ESYAEN 442
Cdd:COG0707 264 SRAGASTVAELAALGKPAILVPLpHAaddHQTKNARALVEAGAAVLIpqSELTPEK---LAEALEELLEDperlAKMAEA 340


                ....*.
gi 71992260 443 AEKLAK 448
Cdd:COG0707 341 ARALAR 346
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 356-411 4.99e-05

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 45.74  E-value: 4.99e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260  356 WTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNG 411
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNAALLSDELG 400
PLN03015 PLN03015
UDP-glucosyl transferase
 351-411 1.16e-04

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 44.68  E-value: 1.16e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71992260  351 IIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNG 411
Cdd:PLN03015 337 LVVTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNATLLTEEIG 397
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 375-449 1.76e-04

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 43.97  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  375 GGLGSVNELSYLGKPALLCPL-FA---DQVRNSKMLSRHNGSIEI--SKFNLEsynTLRSALHSILFD----ESYAENAE 444
Cdd:PRK00726 260 AGASTVAELAAAGLPAILVPLpHAaddHQTANARALVDAGAALLIpqSDLTPE---KLAEKLLELLSDperlEAMAEAAR 336


                 ....*
gi 71992260  445 KLAKK 449
Cdd:PRK00726 337 ALGKP 341
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 356-418 3.59e-04

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 43.24  E-value: 3.59e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71992260  356 WTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNG-SIEISKF 418
Cdd:PLN02554 349 WAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMVEELGlAVEIRKY 412
PLN02534 PLN02534
UDP-glycosyltransferase
 351-406 4.92e-04

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 42.54  E-value: 4.92e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260  351 IIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKML 406
Cdd:PLN02534 346 LLIKGWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLI 401
PLN00164 PLN00164
glucosyltransferase; Provisional
 355-411 8.70e-04

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 41.97  E-value: 8.70e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 71992260  355 KWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNG 411
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNAFELVADMG 401
PLN02207 PLN02207
UDP-glycosyltransferase
 333-408 9.61e-04

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 41.56  E-value: 9.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  333 FIWKYESEETS----FANGAENIIFKK-----WTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNS 403
Cdd:PLN02207 307 FLWSLRTEEVTnddlLPEGFLDRVSGRgmicgWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNA 386


                 ....*
gi 71992260  404 KMLSR 408
Cdd:PLN02207 387 FLMVK 391
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 361-449 1.00e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 41.43  E-value: 1.00e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260 361 ALLADSRLSafFTHGGLGSVNELSYLGKPALLCPL-FA---DQVRNSKMLSRHNGSIEISKFNLeSYNTLRSALHSILFD 436
Cdd:cd03785 248 AAYAAADLV--ISRAGASTIAELTAAGKPAILIPYpYAaddHQEANARALEKAGAAIVIDQEEL-TPEVLAEAILDLLND 324

                        90
                ....*....|....*..
gi 71992260 437 ----ESYAENAEKLAKK 449
Cdd:cd03785 325 perlKKMAEAAKKLAKP 341
PLN02670 PLN02670
transferase, transferring glycosyl groups
 333-417 2.21e-03

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 40.66  E-value: 2.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71992260  333 FIWKYESEETSFANGAENI-------------IFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQ 399
Cdd:PLN02670 310 FFWVLRNEPGTTQNALEMLpdgfeervkgrgmIHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQ 389

                         90
                 ....*....|....*...
gi 71992260  400 VRNSKMLSRHNGSIEISK 417
Cdd:PLN02670 390 GLNTRLLHGKKLGLEVPR 407
PLN03004 PLN03004
UDP-glycosyltransferase
 351-406 5.22e-03

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 39.29  E-value: 5.22e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 71992260  351 IIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSKML 406
Cdd:PLN03004 336 MVVKSWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMI 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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