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Conserved domains on  [gi|17538816|ref|NP_502427|]
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BACK domain-containing protein [Caenorhabditis elegans]

Protein Classification

BACK domain-containing protein( domain architecture ID 10657908)

BACK (BTB and C-terminal Kelch) domain-containing protein similar to Vaccinia virus Copenhagen Protein C5

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BACK smart00875
BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are ...
157-241 2.77e-12

BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues.


:

Pssm-ID: 197943 [Multi-domain]  Cd Length: 101  Bit Score: 62.74  E-value: 2.77e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816    157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWL--NGQNHVnAFAPSLLSCI 234
Cdd:smart00875  10 AHGLEELAEKALRFILQNFSEVSSSEEFLELPLEQLLELLSSDDLNVSSEEEVFEAVLRWVkhDPEKRR-EHLPELLEHV 88

                   ....*..
gi 17538816    235 RTKFLSP 241
Cdd:smart00875  89 RLPLLSP 95
 
Name Accession Description Interval E-value
BACK smart00875
BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are ...
157-241 2.77e-12

BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues.


Pssm-ID: 197943 [Multi-domain]  Cd Length: 101  Bit Score: 62.74  E-value: 2.77e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816    157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWL--NGQNHVnAFAPSLLSCI 234
Cdd:smart00875  10 AHGLEELAEKALRFILQNFSEVSSSEEFLELPLEQLLELLSSDDLNVSSEEEVFEAVLRWVkhDPEKRR-EHLPELLEHV 88

                   ....*..
gi 17538816    235 RTKFLSP 241
Cdd:smart00875  89 RLPLLSP 95
PHA03098 PHA03098
kelch-like protein; Provisional
169-241 2.53e-07

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 53.23  E-value: 2.53e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17538816  169 NFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLNGQNHVNAFAPSL-LSCIRTKFLSP 241
Cdd:PHA03098 131 NYIRNNIELIYNDPDFIYLSKNELIKILSDDKLNVSSEDVVLEIIIKWLTSKKNNKYKDICLiLKVLRITFLSE 204
BACK pfam07707
BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The ...
157-241 2.57e-07

BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. This family appears to be closely related to the BTB domain (Finn RD, personal observation).


Pssm-ID: 462237 [Multi-domain]  Cd Length: 103  Bit Score: 48.70  E-value: 2.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816   157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLN-GQNHVNAFAPSLLSCIR 235
Cdd:pfam07707  10 AYGCTELAEAALRFILQNFLEVAKSEEFLELSLEQLLELLSSDDLNVPSEEEVFEAVIRWVKhDVERRKKHLPELLSAVR 89

                  ....*.
gi 17538816   236 TKFLSP 241
Cdd:pfam07707  90 LPLLSP 95
BACK_KLHL6 cd18446
BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 6 (KLHL6); KLHL6 is a ...
157-241 4.70e-04

BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 6 (KLHL6); KLHL6 is a BTB-kelch protein with a lymphoid tissue-restricted expression pattern. It belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain and four to six Kelch motifs in tandem. It is involved in B-lymphocyte antigen receptor signaling and germinal center formation.


Pssm-ID: 350521 [Multi-domain]  Cd Length: 108  Bit Score: 39.76  E-value: 4.70e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816 157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLNGQ-NHVNAFAPSLLSCIR 235
Cdd:cd18446  15 AHSLESLKKQVQNYIIQNFSQVLNHEEFLELPVDILCHILKSDDLYVTEEEQVFETVMRWVRYKeSERLPLLPRVLENVR 94

                ....*.
gi 17538816 236 TKFLSP 241
Cdd:cd18446  95 LPLLDP 100
 
Name Accession Description Interval E-value
BACK smart00875
BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are ...
157-241 2.77e-12

BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues.


Pssm-ID: 197943 [Multi-domain]  Cd Length: 101  Bit Score: 62.74  E-value: 2.77e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816    157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWL--NGQNHVnAFAPSLLSCI 234
Cdd:smart00875  10 AHGLEELAEKALRFILQNFSEVSSSEEFLELPLEQLLELLSSDDLNVSSEEEVFEAVLRWVkhDPEKRR-EHLPELLEHV 88

                   ....*..
gi 17538816    235 RTKFLSP 241
Cdd:smart00875  89 RLPLLSP 95
PHA03098 PHA03098
kelch-like protein; Provisional
169-241 2.53e-07

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 53.23  E-value: 2.53e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17538816  169 NFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLNGQNHVNAFAPSL-LSCIRTKFLSP 241
Cdd:PHA03098 131 NYIRNNIELIYNDPDFIYLSKNELIKILSDDKLNVSSEDVVLEIIIKWLTSKKNNKYKDICLiLKVLRITFLSE 204
BACK pfam07707
BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The ...
157-241 2.57e-07

BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. This family appears to be closely related to the BTB domain (Finn RD, personal observation).


Pssm-ID: 462237 [Multi-domain]  Cd Length: 103  Bit Score: 48.70  E-value: 2.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816   157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLN-GQNHVNAFAPSLLSCIR 235
Cdd:pfam07707  10 AYGCTELAEAALRFILQNFLEVAKSEEFLELSLEQLLELLSSDDLNVPSEEEVFEAVIRWVKhDVERRKKHLPELLSAVR 89

                  ....*.
gi 17538816   236 TKFLSP 241
Cdd:pfam07707  90 LPLLSP 95
BACK_KLHL6 cd18446
BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 6 (KLHL6); KLHL6 is a ...
157-241 4.70e-04

BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 6 (KLHL6); KLHL6 is a BTB-kelch protein with a lymphoid tissue-restricted expression pattern. It belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain and four to six Kelch motifs in tandem. It is involved in B-lymphocyte antigen receptor signaling and germinal center formation.


Pssm-ID: 350521 [Multi-domain]  Cd Length: 108  Bit Score: 39.76  E-value: 4.70e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538816 157 AHVNPDTEKSLQNFAIESIEKLVALPDFHKVPFHQLYQILSSCELVVTHEMFVADVILLWLNGQ-NHVNAFAPSLLSCIR 235
Cdd:cd18446  15 AHSLESLKKQVQNYIIQNFSQVLNHEEFLELPVDILCHILKSDDLYVTEEEQVFETVMRWVRYKeSERLPLLPRVLENVR 94

                ....*.
gi 17538816 236 TKFLSP 241
Cdd:cd18446  95 LPLLDP 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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