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Conserved domains on  [gi|17542596|ref|NP_501526|]
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Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.34e-22

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 88.29  E-value: 1.34e-22
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17542596     12 FVAYSAVAFSVVAVISVCVTLPMVYNYVHHVKRTMHSEINFCKGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-279 2.79e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 2.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGrPPQQPCEPITPPPCKPCPA 150
Cdd:NF038329 133 EQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG-PQGPRGETGPAGEQGPAGP 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  151 GPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPitpgaPGPAGPAGPQGPP 230
Cdd:NF038329 212 AGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPA 286

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 17542596  231 GAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQAGTSGGAGEKG 279
Cdd:NF038329 287 GKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.34e-22

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 88.29  E-value: 1.34e-22
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17542596     12 FVAYSAVAFSVVAVISVCVTLPMVYNYVHHVKRTMHSEINFCKGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 15-64 2.15e-19

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 79.81  E-value: 2.15e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17542596    15 YSAVAFSVVAVISVCVTLPMVYNYVHHVKRTMHSEINFCKGSAKDIWSEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-279 2.79e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 2.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGrPPQQPCEPITPPPCKPCPA 150
Cdd:NF038329 133 EQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG-PQGPRGETGPAGEQGPAGP 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  151 GPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPitpgaPGPAGPAGPQGPP 230
Cdd:NF038329 212 AGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPA 286

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 17542596  231 GAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQAGTSGGAGEKG 279
Cdd:NF038329 287 GKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 102-279 4.47e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.08  E-value: 4.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  102 PGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITPPPC---KPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDG 178
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  179 QPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPITPGAPGPAGPAGPQGPPGAPGQPGHDGQPGAPGPKGPNGNPGAPG 258
Cdd:NF038329 202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERG 281

                        170       180
                 ....*....|....*....|.
gi 17542596  259 ADGNPGAPGQAGTSGGAGEKG 279
Cdd:NF038329 282 PVGPAGKDGQNGKDGLPGKDG 302
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-270 1.55e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 1.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGR-----PPQQPCEPITPPPC 145
Cdd:NF038329 136 PRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPrgetgPAGEQGPAGPAGPD 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  146 KPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPItpGAPGPAGPAG 225
Cdd:NF038329 216 GEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPV--GPAGKDGQNG 293

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 17542596  226 PQGPPGAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQAG 270
Cdd:NF038329 294 KDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 86-277 8.32e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.45  E-value: 8.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   86 VTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQ-QPCEPITPPPCKPCPAGPAGAPGPAGPAGD 164
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAApAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  165 AGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSepitPGAPGPAGPAGPQGPPGAPGQPGHDGQPGA 244
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG----QADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                        170       180       190
                 ....*....|....*....|....*....|...
gi 17542596  245 PGPKGPNGNPGAPGADGNPGAPGQAGTSGGAGE 277
Cdd:PRK07764 743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-250 3.70e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 51.06  E-value: 3.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITP-------- 142
Cdd:NF038329 175 PAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEdgpqgpdg 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  143 PPCKPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPitpgapgpag 222
Cdd:NF038329 255 PAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGK---------- 324

                        170       180
                 ....*....|....*....|....*...
gi 17542596  223 pagpQGPPGAPGQpghDGQPGAPGPKGP 250
Cdd:NF038329 325 ----DGLPGKDGK---DGQPGKPAPKTP 345
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 170-209 1.68e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 35.93  E-value: 1.68e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 17542596   170 NPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAP 209
Cdd:pfam01391  14 PPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 83-206 6.88e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.96  E-value: 6.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   83 DAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITPPPCKPCPAGPAGAPGPAGPA 162
Cdd:NF038329 240 DPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKD 319

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 17542596  163 GDAGANGNPGAPGNDGQPGAPGNKG---PSGPNGNPGAPGAPGQPGQ 206
Cdd:NF038329 320 GQPGKDGLPGKDGKDGQPGKPAPKTpevPQKPDTAPHTPKTPQIPGQ 366
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.34e-22

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 88.29  E-value: 1.34e-22
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17542596     12 FVAYSAVAFSVVAVISVCVTLPMVYNYVHHVKRTMHSEINFCKGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 15-64 2.15e-19

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 79.81  E-value: 2.15e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17542596    15 YSAVAFSVVAVISVCVTLPMVYNYVHHVKRTMHSEINFCKGSAKDIWSEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-279 2.79e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.63  E-value: 2.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGrPPQQPCEPITPPPCKPCPA 150
Cdd:NF038329 133 EQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG-PQGPRGETGPAGEQGPAGP 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  151 GPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPitpgaPGPAGPAGPQGPP 230
Cdd:NF038329 212 AGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPA 286

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 17542596  231 GAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQAGTSGGAGEKG 279
Cdd:NF038329 287 GKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 102-279 4.47e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.08  E-value: 4.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  102 PGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITPPPC---KPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDG 178
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  179 QPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPITPGAPGPAGPAGPQGPPGAPGQPGHDGQPGAPGPKGPNGNPGAPG 258
Cdd:NF038329 202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERG 281

                        170       180
                 ....*....|....*....|.
gi 17542596  259 ADGNPGAPGQAGTSGGAGEKG 279
Cdd:NF038329 282 PVGPAGKDGQNGKDGLPGKDG 302
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-270 1.55e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 1.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGR-----PPQQPCEPITPPPC 145
Cdd:NF038329 136 PRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPrgetgPAGEQGPAGPAGPD 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  146 KPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPItpGAPGPAGPAG 225
Cdd:NF038329 216 GEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPV--GPAGKDGQNG 293

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 17542596  226 PQGPPGAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQAG 270
Cdd:NF038329 294 KDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 86-277 8.32e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.45  E-value: 8.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   86 VTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQ-QPCEPITPPPCKPCPAGPAGAPGPAGPAGD 164
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAApAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  165 AGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSepitPGAPGPAGPAGPQGPPGAPGQPGHDGQPGA 244
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG----QADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                        170       180       190
                 ....*....|....*....|....*....|...
gi 17542596  245 PGPKGPNGNPGAPGADGNPGAPGQAGTSGGAGE 277
Cdd:PRK07764 743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 71-250 3.70e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 51.06  E-value: 3.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   71 PSGNRTARQAGYDAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITP-------- 142
Cdd:NF038329 175 PAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEdgpqgpdg 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  143 PPCKPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAPSEPitpgapgpag 222
Cdd:NF038329 255 PAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGK---------- 324

                        170       180
                 ....*....|....*....|....*...
gi 17542596  223 pagpQGPPGAPGQpghDGQPGAPGPKGP 250
Cdd:NF038329 325 ----DGLPGKDGK---DGQPGKPAPKTP 345
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 78-214 6.27e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 44.29  E-value: 6.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   78 RQAGYDAGVTGGSASAGGCDACC----LPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRP-PQQPCEPITPPPCKpcpagp 152
Cdd:PRK14959 372 RPSGGGASAPSGSAAEGPASGGAatipTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPsPRVPWDDAPPAPPR------ 445

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17542596  153 agapgpagpaGDAGANGNPGAPGNDGQPGAPGNKGPSGpnGNPGAPGAPGQPGQDAPSEPIT 214
Cdd:PRK14959 446 ----------SGIPPRPAPRMPEASPVPGAPDSVASAS--DAPPTLGDPSDTAEHTPSGPRT 495
PHA03247 PHA03247
large tegument protein UL36; Provisional
 100-266 5.15e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 5.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   100 CLPGAAGPAGTP--GKPGRPGKPGAPGLPGNPGRPPQQPCEPITPPPCKPCPAGPAGAPGPAGPAGDAGANGNPGAPGND 177
Cdd:PHA03247 2573 PAPRPSEPAVTSraRRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERP 2652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   178 GQPGAPGN-------------KGPSGPNGNPGAPGAPGQPGQDA------PSEPITPGAPGPAGPAGPQGPPGAPGQPGH 238
Cdd:PHA03247 2653 RDDPAPGRvsrprrarrlgraAQASSPPQRPRRRAARPTVGSLTsladppPPPPTPEPAPHALVSATPLPPGPAAARQAS 2732

                         170       180
                  ....*....|....*....|....*...
gi 17542596   239 DGQPGAPGPKGPNGNPGAPGADGNPGAP 266
Cdd:PHA03247 2733 PALPAAPAPPAVPAGPATPGGPARPARP 2760
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
78-269 9.78e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 9.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   78 RQAGYDAGVTGGSASAGGCDACcLPGAAGPAG--TPGKPGRPGKPGAPGLPGNPGRPP------QQPCEPITPPPCKPCP 149
Cdd:PRK07003 354 RMLAFEPAVTGGGAPGGGVPAR-VAGAVPAPGarAAAAVGASAVPAVTAVTGAAGAALapkaaaAAAATRAEAPPAAPAP 432

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596  150 AGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGNKGPSGPngNPGAPGAPGQPgQDAPSEPITPGAPGPAGPAGPQGP 229
Cdd:PRK07003 433 PATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADS--GSASAPASDAP-PDAAFEPAPRAAAPSAATPAAVPD 509

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 17542596  230 PGAPGQPGHDGQPGAPGPKGPNGNPGAPGADGNPGAPGQA 269
Cdd:PRK07003 510 ARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGA 549
PHA03247 PHA03247
large tegument protein UL36; Provisional
 104-266 1.36e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   104 AAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITPP-------PCKPCPAGPAGAPGPAGPAGDAGANGN-PGAPG 175
Cdd:PHA03247 2673 AAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPhalvsatPLPPGPAAARQASPALPAAPAPPAVPAgPATPG 2752

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   176 NDGQPGAP----GNKGPSGPNGNPGAPGAPGQPGQDAPSEPITPGAPGPAGPAGPQGPPGAPGQPGHDGQ-PGAPGPKGP 250
Cdd:PHA03247 2753 GPARPARPpttaGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAAsPAGPLPPPT 2832

                         170
                  ....*....|....*.
gi 17542596   251 NGNPGAPGADGNPGAP 266
Cdd:PHA03247 2833 SAQPTAPPPPPGPPPP 2848
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 170-209 1.68e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 35.93  E-value: 1.68e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 17542596   170 NPGAPGNDGQPGAPGNKGPSGPNGNPGAPGAPGQPGQDAP 209
Cdd:pfam01391  14 PPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 56-212 1.72e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 1.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   56 SAKDIWSEVNHLKAIPSGNRTARQAGYDAGVTGGSASAGGCDacclPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQ 135
Cdd:PRK07764 634 AAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG----AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP 709

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17542596  136 PCEPITPPPCKPCPAGPAGAPGPAGPAGDAGANGNPGAPGNDGQPGAPGnkGPSGPNGNPGAPGAPGQPGQDAPSEP 212
Cdd:PRK07764 710 PAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQP--PPPPAPAPAAAPAAAPPPSPPSEEEE 784
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 83-206 6.88e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.96  E-value: 6.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542596   83 DAGVTGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCEPITPPPCKPCPAGPAGAPGPAGPA 162
Cdd:NF038329 240 DPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKD 319

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 17542596  163 GDAGANGNPGAPGNDGQPGAPGNKG---PSGPNGNPGAPGAPGQPGQ 206
Cdd:NF038329 320 GQPGKDGLPGKDGKDGQPGKPAPKTpevPQKPDTAPHTPKTPQIPGQ 366
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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