NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17538788|ref|NP_501344|]
View 

Dynactin subunit 4 [Caenorhabditis elegans]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Dynactin_p62 super family cl20296
Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or ...
 25-103 1.64e-08

Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein. p62 binds directly to the Arp1 subunit of dynactin.


The actual alignment was detected with superfamily member pfam05502:

Pssm-ID: 428497  Cd Length: 474  Bit Score: 56.20  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538788    25 LVFCRYCFKIKCDDCSLGEVDNIFCPRCL--EPSSVpeARLKKHKCA-SCNDCPKCANVLS------ARTENDNV----- 90
Cdd:pfam05502   5 LLYCEDCHQIRCPRCVTEEIVTWYCPNCLfeVPSSN--VKSEGNRCTrSCFQCPICISPLAvtslenPPDPLGGAgashg 82

                          90
                  ....*....|....*.
gi 17538788    91 ---YLVCQYCRWSSRE 103
Cdd:pfam05502  83 gpyILSCSYCMWSSLE 98
 
Name Accession Description Interval E-value
Dynactin_p62 pfam05502
Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or ...
 25-103 1.64e-08

Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein. p62 binds directly to the Arp1 subunit of dynactin.


Pssm-ID: 428497  Cd Length: 474  Bit Score: 56.20  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538788    25 LVFCRYCFKIKCDDCSLGEVDNIFCPRCL--EPSSVpeARLKKHKCA-SCNDCPKCANVLS------ARTENDNV----- 90
Cdd:pfam05502   5 LLYCEDCHQIRCPRCVTEEIVTWYCPNCLfeVPSSN--VKSEGNRCTrSCFQCPICISPLAvtslenPPDPLGGAgashg 82

                          90
                  ....*....|....*.
gi 17538788    91 ---YLVCQYCRWSSRE 103
Cdd:pfam05502  83 gpyILSCSYCMWSSLE 98
 
Name Accession Description Interval E-value
Dynactin_p62 pfam05502
Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or ...
 25-103 1.64e-08

Dynactin p62 family; Dynactin is a multi-subunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein. p62 binds directly to the Arp1 subunit of dynactin.


Pssm-ID: 428497  Cd Length: 474  Bit Score: 56.20  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17538788    25 LVFCRYCFKIKCDDCSLGEVDNIFCPRCL--EPSSVpeARLKKHKCA-SCNDCPKCANVLS------ARTENDNV----- 90
Cdd:pfam05502   5 LLYCEDCHQIRCPRCVTEEIVTWYCPNCLfeVPSSN--VKSEGNRCTrSCFQCPICISPLAvtslenPPDPLGGAgashg 82

                          90
                  ....*....|....*.
gi 17538788    91 ---YLVCQYCRWSSRE 103
Cdd:pfam05502  83 gpyILSCSYCMWSSLE 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH