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Conserved domains on  [gi|17540726|ref|NP_499991|]
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Mitochondrial import inner membrane translocase subunit Tim21 [Caenorhabditis elegans]

Protein Classification

Coa1/Tim21 domain-containing protein; cytochrome c oxidase assembly factor 1 family protein( domain architecture ID 10550651)

Coa1/Tim21 domain-containing protein such as mitochondrial import inner membrane translocase subunit Tim21, an essential component of the TIM23 complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane| cytochrome c oxidase assembly factor 1 family protein similar to Saccharomyces cerevisiae cytochrome c oxidase assembly factor 1 that is required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 73-213 3.99e-60

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


:

Pssm-ID: 311963  Cd Length: 145  Bit Score: 185.19  E-value: 3.99e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540726    73 KVAEKASNTFMYTAVVAGIGLIGAFIYVLAGEFFAQDSPQTIFNKALALVRDDGRCQEIFGASIAGFGEETSRGR----R 148
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLLGERIKAYGEETRRGRwtrnR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17540726   149 RHVAHHKYEKDGMQRIRVLFHVKGDRDEGIAQAEMEQRDGDWQWRFLYVENKRRPKTTHVLIDNR 213
Cdd:pfam08294  81 PIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 73-213 3.99e-60

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


Pssm-ID: 311963  Cd Length: 145  Bit Score: 185.19  E-value: 3.99e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540726    73 KVAEKASNTFMYTAVVAGIGLIGAFIYVLAGEFFAQDSPQTIFNKALALVRDDGRCQEIFGASIAGFGEETSRGR----R 148
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLLGERIKAYGEETRRGRwtrnR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17540726   149 RHVAHHKYEKDGMQRIRVLFHVKGDRDEGIAQAEMEQRDGDWQWRFLYVENKRRPKTTHVLIDNR 213
Cdd:pfam08294  81 PIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Name Accession Description Interval E-value
TIM21 pfam08294
TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of ...
 73-213 3.99e-60

TIM21; TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.


Pssm-ID: 311963  Cd Length: 145  Bit Score: 185.19  E-value: 3.99e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17540726    73 KVAEKASNTFMYTAVVAGIGLIGAFIYVLAGEFFAQDSPQTIFNKALALVRDDGRCQEIFGASIAGFGEETSRGR----R 148
Cdd:pfam08294   1 KVKEATTFTFYFIIVLGGVGVTGLVIYLIFSELFSPSGDTQIFNRAVELVEENERVRDLLGERIKAYGEETRRGRwtrnR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17540726   149 RHVAHHKYEKDGMQRIRVLFHVKGDRDEGIAQAEMEQRDGDWQWRFLYVENKRRPKTTHVLIDNR 213
Cdd:pfam08294  81 PIVSTREYDKDGKEHIRMQFHVEGPRKKGTVHLELVESDDSGQYEFRYLYVDVPGHKRIYLEDNR 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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