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Conserved domains on  [gi|17541430|ref|NP_499963|]
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Putative bolA-like protein K11H12.1 [Caenorhabditis elegans]

Protein Classification

BolA family protein( domain architecture ID 10000955)

BolA family protein may be a stress-responsive transcriptional regulator and may also participate in iron metabolism; similar to mammalian BolA-like proteins that act as iron-sulfur (Fe-S) cluster assembly factors that facilitate [2Fe-2S] cluster insertion into a subset of cytosolic proteins, and to Haemophilus influenzae DNA-binding transcriptional regulator BolA

CATH:  3.30.300.90

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 8-94 1.74e-34

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


:

Pssm-ID: 440041  Cd Length: 90  Bit Score: 113.74  E-value: 1.74e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   8 PVARLLKEKLFAAFQPKHLEVECESHLHNVPKGA--EKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDA 85
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGAggESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 17541430  86 IPTSKWDGQ 94
Cdd:COG0271  82 YTPEEWQAR 90
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 8-94 1.74e-34

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 113.74  E-value: 1.74e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   8 PVARLLKEKLFAAFQPKHLEVECESHLHNVPKGA--EKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDA 85
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGAggESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 17541430  86 IPTSKWDGQ 94
Cdd:COG0271  82 YTPEEWQAR 90
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 19-85 1.11e-30

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 103.69  E-value: 1.11e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17541430    19 AAFQPKHLEVECESHLHNVPK-GAEKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDA 85
Cdd:pfam01722   3 EALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKT 70
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 13-105 3.01e-30

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 103.71  E-value: 3.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   13 LKEKLFAAFQPKHLEVECESHLHNVPKGAEKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDAIPTSKWD 92
Cdd:PRK11628   7 IEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWE 86

                         90
                 ....*....|....*
gi 17541430   93 GQKQE--DSPTCRGG 105
Cdd:PRK11628  87 GLQDTvfASPPCRGA 101
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 8-94 1.74e-34

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 113.74  E-value: 1.74e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   8 PVARLLKEKLFAAFQPKHLEVECESHLHNVPKGA--EKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDA 85
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGAggESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 17541430  86 IPTSKWDGQ 94
Cdd:COG0271  82 YTPEEWQAR 90
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 19-85 1.11e-30

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 103.69  E-value: 1.11e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17541430    19 AAFQPKHLEVECESHLHNVPK-GAEKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDA 85
Cdd:pfam01722   3 EALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKT 70
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 13-105 3.01e-30

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 103.71  E-value: 3.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   13 LKEKLFAAFQPKHLEVECESHLHNVPKGAEKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELATTVHALRIDAIPTSKWD 92
Cdd:PRK11628   7 IEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWE 86

                         90
                 ....*....|....*
gi 17541430   93 GQKQE--DSPTCRGG 105
Cdd:PRK11628  87 GLQDTvfASPPCRGA 101
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
9-96 1.03e-11

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 55.93  E-value: 1.03e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17541430   9 VARLLKEKLFAAfqpkHLEVEceshlhnvpkGAEKHFRVQVVSDEFEGKRVIERHRLVNTCLAKELAT-TVHALRIDAIP 87
Cdd:COG5007   6 IKQLIEAGLPCA----EVEVE----------GDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASgEIHALSIKTYT 71


                ....*....
gi 17541430  88 TSKWDGQKQ 96
Cdd:COG5007  72 PEEWAAQRK 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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