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Conserved domains on  [gi|193206654|ref|NP_499944|]
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Amino acid transporter [Caenorhabditis elegans]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
11-442 3.28e-111

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 336.03  E-value: 3.28e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   11 LLVFTLIAVGIGFASGILLrqfdlsDNARNLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYL 89
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   90 TTVIIASCIGVAMVFLFHPGdpdmrSHRPEDVVIREDNNISALDSILDLIRNMFPQNIVEATMyrsqtafvvvrkkilkn 169
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPG-----SGLALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALA----------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  170 gtitpvlmrktikltqGTNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD 249
Cdd:pfam00375 133 ----------------EGNVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  250 IDdlYKMVTTMALYVFTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEENLHVD 329
Cdd:pfam00375 197 YG--LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVS 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVNLPVS 408
Cdd:pfam00375 275 ESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPgGGLVALGLVLSALGLPLE 354

                         410       420       430
                  ....*....|....*....|....*....|....
gi 193206654  409 DIALLFTVDWFIDRVRTALNVLGDAYCACVVQHF 442
Cdd:pfam00375 355 GIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
11-442 3.28e-111

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 336.03  E-value: 3.28e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   11 LLVFTLIAVGIGFASGILLrqfdlsDNARNLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYL 89
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   90 TTVIIASCIGVAMVFLFHPGdpdmrSHRPEDVVIREDNNISALDSILDLIRNMFPQNIVEATMyrsqtafvvvrkkilkn 169
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPG-----SGLALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALA----------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  170 gtitpvlmrktikltqGTNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD 249
Cdd:pfam00375 133 ----------------EGNVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  250 IDdlYKMVTTMALYVFTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEENLHVD 329
Cdd:pfam00375 197 YG--LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVS 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVNLPVS 408
Cdd:pfam00375 275 ESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPgGGLVALGLVLSALGLPLE 354

                         410       420       430
                  ....*....|....*....|....*....|....
gi 193206654  409 DIALLFTVDWFIDRVRTALNVLGDAYCACVVQHF 442
Cdd:pfam00375 355 GIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
11-442 1.22e-101

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 312.05  E-value: 1.22e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  11 LLVFTLIAVGIGFASGILLRQFDLSdnarnLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYL 89
Cdd:COG1301    5 LTLQILIALVLGILLGLLLPELVAA-----VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  90 TTVIIASCIGVAMVFLFHPGdpdmrSHRPEDVVIREDNNISALDSILDLIRNMFPQNIVEAtmyrsqtafvvvrkkilkn 169
Cdd:COG1301   80 VTTTIALVIGLVVANLFQPG-----AGLNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 170 gtitpvlmrktikLTQGtNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD 249
Cdd:COG1301  136 -------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAK 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 250 IDdlYKMVTTMALYVFTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEENLHVD 329
Cdd:COG1301  202 YG--LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVS 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVNLPVS 408
Cdd:COG1301  280 KSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPgAGLVMLAAVLSAVGLPLE 359

                        410       420       430
                 ....*....|....*....|....*....|....
gi 193206654 409 DIALLFTVDWFIDRVRTALNVLGDAYCACVVQHF 442
Cdd:COG1301  360 GIALILGIDRILDMARTAVNVTGDAVATVVVAKW 393
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 16-439 1.52e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 123.72  E-value: 1.52e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  16 LIAVGIGFASGILLRQFDLSDN--ARNLVGFPGEIFMQVLKLMVLPLIFSSLISSL-GQMDASRSGKMSFIAIAYYLTTV 92
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDwlVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIaGVGDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  93 IIASCIGVAMVFLFHPG-----------DPDMRSHRPEDVvirEDNNISALDSILDLIrnmfPQNIVEAtmyrsqtafvv 161
Cdd:PRK11283  93 TVAIILGITLANVFQPGagidmsqlatvDISKYQSTTEEV---QSHSHGLMGTILSLI----PTNIFAS----------- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 162 vrkkiLKNGTITPVlmrktikltqgtnilglIVFCTGFGIVISKLGGKVRV-IVEFFIVLDKVVMKFISVLMLFAPFGIV 240
Cdd:PRK11283 155 -----MAKGEMLPI-----------------IFFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTHMVMRYAPVGVF 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 241 SLIASSVLDID-----DLYKMVttMALYVFTIMCSLFLHCVIAVptlyffITKKSPIDVAKGMVQPFVTAIGTASSGASL 315
Cdd:PRK11283 213 ALIAVTVANFGfaslwPLAKLV--LLVYFAILFFALVVLGIVAR------LCGLSIWILIRILKDELILAYSTASSETVL 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 316 PQAMSSVEEnLHVDARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVPA-GLV 394
Cdd:PRK11283 285 PRIIEKMEA-YGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGvSFV 363

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 193206654 395 SMFVILSSVNLPVSDIALLFTVDWFIDRVRTALNVLGDAYCACVV 439
Cdd:PRK11283 364 VLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVI 408
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
11-442 3.28e-111

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 336.03  E-value: 3.28e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   11 LLVFTLIAVGIGFASGILLrqfdlsDNARNLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYL 89
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654   90 TTVIIASCIGVAMVFLFHPGdpdmrSHRPEDVVIREDNNISALDSILDLIRNMFPQNIVEATMyrsqtafvvvrkkilkn 169
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPG-----SGLALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALA----------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  170 gtitpvlmrktikltqGTNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD 249
Cdd:pfam00375 133 ----------------EGNVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  250 IDdlYKMVTTMALYVFTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEENLHVD 329
Cdd:pfam00375 197 YG--LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVS 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVNLPVS 408
Cdd:pfam00375 275 ESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPgGGLVALGLVLSALGLPLE 354

                         410       420       430
                  ....*....|....*....|....*....|....
gi 193206654  409 DIALLFTVDWFIDRVRTALNVLGDAYCACVVQHF 442
Cdd:pfam00375 355 GIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
11-442 1.22e-101

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 312.05  E-value: 1.22e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  11 LLVFTLIAVGIGFASGILLRQFDLSdnarnLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYL 89
Cdd:COG1301    5 LTLQILIALVLGILLGLLLPELVAA-----VLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLYFL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  90 TTVIIASCIGVAMVFLFHPGdpdmrSHRPEDVVIREDNNISALDSILDLIRNMFPQNIVEAtmyrsqtafvvvrkkilkn 169
Cdd:COG1301   80 VTTTIALVIGLVVANLFQPG-----AGLNLDLADAAAAEAAEAPSLLDFLLNIIPSNIFEA------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 170 gtitpvlmrktikLTQGtNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD 249
Cdd:COG1301  136 -------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAK 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 250 IDdlYKMVTTMALYVFTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEENLHVD 329
Cdd:COG1301  202 YG--LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVS 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVNLPVS 408
Cdd:COG1301  280 KSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPgAGLVMLAAVLSAVGLPLE 359

                        410       420       430
                 ....*....|....*....|....*....|....
gi 193206654 409 DIALLFTVDWFIDRVRTALNVLGDAYCACVVQHF 442
Cdd:COG1301  360 GIALILGIDRILDMARTAVNVTGDAVATVVVAKW 393
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 16-439 1.52e-30

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 123.72  E-value: 1.52e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  16 LIAVGIGFASGILLRQFDLSDN--ARNLVGFPGEIFMQVLKLMVLPLIFSSLISSL-GQMDASRSGKMSFIAIAYYLTTV 92
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDwlVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIaGVGDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  93 IIASCIGVAMVFLFHPG-----------DPDMRSHRPEDVvirEDNNISALDSILDLIrnmfPQNIVEAtmyrsqtafvv 161
Cdd:PRK11283  93 TVAIILGITLANVFQPGagidmsqlatvDISKYQSTTEEV---QSHSHGLMGTILSLI----PTNIFAS----------- 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 162 vrkkiLKNGTITPVlmrktikltqgtnilglIVFCTGFGIVISKLGGKVRV-IVEFFIVLDKVVMKFISVLMLFAPFGIV 240
Cdd:PRK11283 155 -----MAKGEMLPI-----------------IFFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTHMVMRYAPVGVF 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 241 SLIASSVLDID-----DLYKMVttMALYVFTIMCSLFLHCVIAVptlyffITKKSPIDVAKGMVQPFVTAIGTASSGASL 315
Cdd:PRK11283 213 ALIAVTVANFGfaslwPLAKLV--LLVYFAILFFALVVLGIVAR------LCGLSIWILIRILKDELILAYSTASSETVL 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 316 PQAMSSVEEnLHVDARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVPA-GLV 394
Cdd:PRK11283 285 PRIIEKMEA-YGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGvSFV 363

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*
gi 193206654 395 SMFVILSSVNLPVSDIALLFTVDWFIDRVRTALNVLGDAYCACVV 439
Cdd:PRK11283 364 VLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVI 408
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 16-439 3.68e-29

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 119.39  E-value: 3.68e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  16 LIAVGIGFASGILLRQFdlSDNARNLvgfpGEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYLTTVII 94
Cdd:PRK13027  13 VIALVLGVALGAFFPHF--AESLKPL----GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  95 ASCIGVAMVFLFHPG---DPDMRSHRPEDVVIREDNNiSALDSILDLIRNMFPQNIVEATMyrsqtafvvvrkkilKNgt 171
Cdd:PRK13027  87 ALVIGLVLAYLTGPGvgmNIDLRSLDAASLAGYAKNA-QSLKGTAGFLLKLIPTTAVDAFA---------------KG-- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 172 itpvlmrktikltqgtNILGLIVFCTGFGIVISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSV--LD 249
Cdd:PRK13027 149 ----------------DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAFTTgkYG 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 250 IDDLYKMvtTMALYVFTIMCSLFlhcVIAVPTLYFFITKKSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEeNLHVD 329
Cdd:PRK13027 213 VGSLKQL--GMLVAVFYLTCFVF---VVVVLGAVMRLAGFSVFKLIRYLREELLIVLGTASSDAVLPQVMRKLE-HMGIK 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 330 ARIAGFIMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSV-NLPV 407
Cdd:PRK13027 287 DSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPgSAIVILAATLSAIpAIPV 366

                        410       420       430
                 ....*....|....*....|....*....|..
gi 193206654 408 SDIALLFTVDWFIDRVRTALNVLGDAYCACVV 439
Cdd:PRK13027 367 LGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 46-439 6.80e-27

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 113.07  E-value: 6.80e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  46 GEIFMQVLKLMVLPLIFSSLISSLGQM-DASRSGKMSFIAIAYYLTTVIIASCIGVAMVFLFHPG---DPDMRSHRPEDV 121
Cdd:PRK01663  38 GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGagmNIDPATLDAKAV 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 122 VIREDNniSALDSILDLIRNMFPQNIVEAtmyrsqtafvvvrkkiLKNGTITPVLMrktikltqgtnilglivFCTGFGI 201
Cdd:PRK01663 118 AQYAAQ--AHEQGTVDFLMDIIPTTVVGA----------------FASGDILQVLL-----------------FAVLFGF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 202 VISKLGGKVRVIVEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSV--LDIDDLYKMVTTMALyvFTIMCSLFLHCVI-A 278
Cdd:PRK01663 163 ALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIgkYGVGSLVQLGQLIGC--FYITCILFVFVVLgA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 279 VPTLYFFitkkSPIDVAKGMVQPFVTAIGTASSGASLPQAMSSVEeNLHVDARIAGFIMPLGNTINMDGNALYEAVAVIF 358
Cdd:PRK01663 241 IARLTGF----SIFKFIRYIKEELLIVLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVF 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 359 VAQLNNVTLSFADVITICVTATFASIGLNAVP-AGLVSMFVILSSVN-LPVSDIALLFTVDWFIDRVRTALNVLGDAyCA 436
Cdd:PRK01663 316 IAQATNTPLSIGHQITLLAVLLLTSKGAAGVTgSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNG-VA 394


                 ...
gi 193206654 437 CVV 439
Cdd:PRK01663 395 TVV 397
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 16-431 1.37e-19

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 91.43  E-value: 1.37e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  16 LIAVGIGFASGILLRQFDLSDNAR--------NLVGfpgEIFMQVLKLMVLPLIFSSLISSLGQMDASRS-GKMSFIAIA 86
Cdd:COG1823   35 FTGLGLGILFGLILQLIYGAGSPVikqsidwfNIVG---NGYVRLLQMIVMPLVFVSILSAITKLKNASSlGKISGLIIG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  87 YYLTTVIIASCIGVAMVFLF-------HPGDpdmrshrpedvviREDNNISALDSILDLIRNM-FPQNIVEAtmyrsqta 158
Cdd:COG1823  112 ILLGTTAIAALVGILVALLFgltaeglTQGA-------------AETARGEALEERLGEVEDLsLPQQILSF-------- 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 159 fvvvrkkILKNgtitPVLmrktiKLT--QGTNILGLIVFCTGFGIVISKLGGKVRVIVEFFI----VLDKVVMKFISVLM 232
Cdd:COG1823  171 -------IPTN----PFA-----DLTgaRPTSTIAVVIFAAFLGIAALGLRRKKPEQAETFLkgidALQAIVMRLVRLVL 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 233 LFAPFGIVSLIA-----SSVLDIDDLYKMVttMALYV-FTIMcsLFLHCVIavptlyFFITKKSPIDVAKGMVQPFVTAI 306
Cdd:COG1823  235 RLTPYGVLALMTkvvatSDFADILNLGKFV--VASYVaLIIM--FIVHLLL------LALAGLNPLTYFKKVWPVLTFAF 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 307 GTASSGASLPQAMSSVEENLHVDARIAGFIMPLGNTINMDGNA-LYEAVAVIFVAQ---LNNVTLSFadVITICVTATFA 382
Cdd:COG1823  305 TSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPtvgINPLDPSF--ILTLIAVVTIS 382

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 193206654 383 SIGLNAVPAGLV-SMFVILSSVNLPVSDIALLFTVDWFIDRVRTALNVLG 431
Cdd:COG1823  383 SFGVAGVGGGATfAALIVLSAMGLPVALAGLLISIEPLIDMGRTALNVSG 432
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 17-428 5.36e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 61.42  E-value: 5.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  17 IAVGIgfASGILLRQfdLSDNARNLVGFPGEIFMQVLKLMVLPLIFSSLISSLGQMDASRSGKMSFIAIAYYLTTvIIAS 96
Cdd:PRK13628  20 ILIGL--VLGILLAL--LSPPAAEAVGLLGTLFVGALKAVAPILVFVLVMASIANHKKGQKTNIRPILVLYLLGT-FLAA 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  97 CIGVAMVFLFhpgdpdmrshrPEDVVIR-EDNNISAldsildlirnmfPQNIVEatmyrsqtafvvVRKKILKNGTITPV 175
Cdd:PRK13628  95 LVAVVASFLF-----------PSTLVLVaSAADISP------------PQGIVE------------VLKTLLLSLVDNPI 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 176 lmrktIKLTQGtNILGLIVFCTGFGIVISKLGGKVRvivEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLDiddlyK 255
Cdd:PRK13628 140 -----NALLNA-NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAE-----T 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 256 MVTTMALYVFTIM----CSLFLHCVIAvPTLYFFITKKSPID-VAKGMVQPFVTAIGTASSGASLPQAMSSVEE-NLHVD 329
Cdd:PRK13628 206 GFSALAGYAQLLAvlvgCMLFVALVVN-PLIVFWKIRRNPYPlVFTCLRESGVTAFFTRSSAANIPVNMALCEKlGLDED 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 330 arIAGFIMPLGNTINMDGNALyeAVAVIFVAQLN--NVTLSFADVITICVTATFASIGLNAVPAG---LV----SMFVIL 400
Cdd:PRK13628 285 --TYSVSIPLGATINMAGAAI--TITVLTLAAVHtlGIPVDLPTALLLSVVAAISACGASGVAGGsllLIplacSLFGIS 360

                        410       420
                 ....*....|....*....|....*...
gi 193206654 401 SSVNLPVsdIALLFTVDWFIDRVRTALN 428
Cdd:PRK13628 361 NDIAMQV--VAVGFIIGVLQDSAETALN 386
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 188-441 2.59e-08

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 55.83  E-value: 2.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 188 NILGLIVFCTGFGIVISKLGGKVRvivEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLDiddlyKMVTTMALY---V 264
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVFKTISD-----KGVGSLANYgilL 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 265 FTIMCSLFLHCVIAVPTLYFFITKKSPIDVAKGMVQ-PFVTAIGTASSGASLPQAMSsVEENLHVDARIAGFIMPLGNTI 343
Cdd:PRK14695 132 VLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTI 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 344 NMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVPAGLVSMFVILSSVNLPVSDIALL-----FTVDW 418
Cdd:PRK14695 211 NMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQivgvgFVIGV 290

                        250       260
                 ....*....|....*....|...
gi 193206654 419 FIDRVRTALNVLGDAYCACVVQH 441
Cdd:PRK14695 291 IQDSCETALNSSTDVLFTAVAEY 313
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
21-428 1.71e-07

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 53.64  E-value: 1.71e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654  21 IGFASGILLRQFdlSDNARNLVGFPGEIFMQVLKlMVLP-LIFSSLISSLGQMDASRSGKMSFIAIAYYLTTVIiASCIG 99
Cdd:COG3633   21 IGLVLGILLALL--SPEAAKSVGLLGTLFVGALK-AVAPiLVFVLVMSAIANHKQGQKTNMKPIIVLYLLGTFL-AALVA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 100 VAMVFLFhpgdpdmrshrPEDVVIR-EDNNISAldsildlirnmfPQNIVEatmyrsqtafvvVRKKILKNGTITPVlmr 178
Cdd:COG3633   97 VVASFLF-----------PTTLTLVaAAADLTP------------PGGIGE------------VLKTLLLNVVDNPV--- 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 179 ktIKLTQGtNILGLIVFCTGFGIVISKLGGKVRvivEFFIVLDKVVMKFISVLMLFAPFGIVSLIASSVLD--IDDLYKM 256
Cdd:COG3633  139 --NALANA-NYIGILAWAIGLGLALRHASDTTK---TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATtgFSALLGY 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 257 VTTMALYVftiMCSLFLHCVIAvPTLYFFITKKSPID-VAKGMVQPFVTAIGTASSGASLPQAMSSVEEnLHVDARIAGF 335
Cdd:COG3633  213 AHLLAVLV---GCMLFVALVVN-PLIVFLKIRRNPYPlVFTCLRESGITAFFTRSSAANIPVNMALCEK-LGLDEDTYSV 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193206654 336 IMPLGNTINMDGNALYEAVAVIFVAQLNNVTLSFADVITICVTATFASIGLNAVPAG---LV----SMFVILSSVNLPVs 408
Cdd:COG3633  288 SIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVVAAVSACGASGVAGGsllLIplacSLFGISNDIAMQV- 366

                        410       420
                 ....*....|....*....|
gi 193206654 409 dIALLFTVDWFIDRVRTALN 428
Cdd:COG3633  367 -VAVGFIIGVIQDSAETALN 385
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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