|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
132-287 |
1.17e-59 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 187.34 E-value: 1.17e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLgLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVAT 211
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGV-VVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17555908 212 CDPGAAE--KAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISISPVRK-DGSNVTSLNVSVVAGILLHHI 287
Cdd:cd18105 80 SAPPSASsdKKTIPANELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaENPGVDSLNVSVAAGILLHSL 158
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
21-294 |
6.68e-53 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 173.46 E-value: 6.68e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 21 KMARKSAEKYVAKKIQVPELQGEALF---GLHSVLEAIRSGkRDFHSVFLKKavenraDSDARIKEILSRIDELGIQKTL 97
Cdd:COG0566 2 TSPSNPRVKDLRKLRDKKYREEEGLFlaeGRHAVEEALKAG-REIEELLVTE------GALDRLAELLALAKAAGIPVYE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 98 LTDDQLDRLTEFQLHNGICMDASALQFSNFE-----PKTVSIFV--DKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPkS 170
Cdd:COG0566 75 VSREVLDKLSGTETHQGVLAVVRPPEYADLEdllaeAGEPPLLLvlDGVQDPGNLGAILRSAAAFGVDGVILPKRRAD-P 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 171 ITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcDPGAaekagisAKSLDQWTPEKPVGIVLGDEGVGISRG 250
Cdd:COG0566 154 YNPKVVRASAGALFHVPVARVTNLADALEELKEAGFWVVGT-DLDG-------EASLYEVDLPGPVALVLGNEGKGLSRL 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 17555908 251 ILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLHHISLQNRTN 294
Cdd:COG0566 226 VLEACDELVRI-PMA---GGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
43-290 |
2.99e-36 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 129.77 E-value: 2.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 43 EALFGLHSVLEAIRSGKRdfhsVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASAL 122
Cdd:TIGR00186 2 EYLYGKNAVLEALLNQQR----VFILKGLE-----SKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 123 QFSNFE--PKTVS-------IFVDKVLDPGNLGAIGRSAWYFGADGLgLVKGRGPKSITPAMIKSSCGALEHLPVQQFLN 193
Cdd:TIGR00186 73 LYKDLNdlYKTAKskkqpflLILDEITDPHNLGAILRTAEAFGVDGV-ILPKRRSAPLNSTVVKTSSGAVEYVPLARVTN 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 194 FNEFRDKIKAAGGELVATcdPGAAEKAGISAKSLdqwtpeKPVGIVLGDEGVGISRGILNLCDTVISISPVRKdgsnVTS 273
Cdd:TIGR00186 152 LSRTITKLKESGFWTVGT--DLDAQDTLYQVKLT------KPLALVVGNEGEGVSRLIKENCDFLIKIPMAGK----VDS 219
|
250
....*....|....*..
gi 17555908 274 LNVSVVAGILLHHISLQ 290
Cdd:TIGR00186 220 LNVSVAAGILLFEIKRQ 236
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
132-285 |
1.93e-32 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 116.86 E-value: 1.93e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVAT 211
Cdd:pfam00588 2 LVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVAT 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17555908 212 cDPGaaekagisAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRKDgsnVTSLNVSVVAGILLH 285
Cdd:pfam00588 82 -SLG--------GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRI-PMSGD---VESLNVAVAAAIALY 142
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
43-290 |
4.95e-17 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 78.47 E-value: 4.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 43 EALFGLHSVlEAI--RSGKRdFHSVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICM--- 117
Cdd:PRK11181 3 EIIYGIHAV-QALleRAPER-FIEVFVLKGRE-----DKRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIArvk 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 118 --------DASALqFSNFEPKTVSIfVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGpKSITPAMIKSSCGALEHLPVQ 189
Cdd:PRK11181 76 pgrqlqenDLPDL-LASLEQPFLLI-LDGVTDPHNLGACLRSADAAGVHAVIVPKDRS-AQLNATAKKVACGAAETVPLI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 190 QFLNFNEFRDKIKAAGGELVATcdpgaaekAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdGS 269
Cdd:PRK11181 153 RVTNLARTMRMLQEKNIWIVGT--------AGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISI-PMA--GS 221
|
250 260
....*....|....*....|.
gi 17555908 270 nVTSLNVSVVAGILLHHISLQ 290
Cdd:PRK11181 222 -VSSLNVSVATGICLFEAVRQ 241
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
45-123 |
5.18e-12 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 60.33 E-value: 5.18e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17555908 45 LFGLHSVLEAIRSGKRdFHSVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASALQ 123
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEGRR-----DPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
45-121 |
1.54e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 53.31 E-value: 1.54e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17555908 45 LFGLHSVLEAIRSGKRdFHSVFLKKavenraDSDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASA 121
Cdd:smart00967 1 IEGRHAVEEALKSGRR-IKELYLTE------GRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
132-287 |
1.17e-59 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 187.34 E-value: 1.17e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLgLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVAT 211
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGV-VVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17555908 212 CDPGAAE--KAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISISPVRK-DGSNVTSLNVSVVAGILLHHI 287
Cdd:cd18105 80 SAPPSASsdKKTIPANELSELLLEKPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaENPGVDSLNVSVAAGILLHSL 158
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
21-294 |
6.68e-53 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 173.46 E-value: 6.68e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 21 KMARKSAEKYVAKKIQVPELQGEALF---GLHSVLEAIRSGkRDFHSVFLKKavenraDSDARIKEILSRIDELGIQKTL 97
Cdd:COG0566 2 TSPSNPRVKDLRKLRDKKYREEEGLFlaeGRHAVEEALKAG-REIEELLVTE------GALDRLAELLALAKAAGIPVYE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 98 LTDDQLDRLTEFQLHNGICMDASALQFSNFE-----PKTVSIFV--DKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPkS 170
Cdd:COG0566 75 VSREVLDKLSGTETHQGVLAVVRPPEYADLEdllaeAGEPPLLLvlDGVQDPGNLGAILRSAAAFGVDGVILPKRRAD-P 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 171 ITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcDPGAaekagisAKSLDQWTPEKPVGIVLGDEGVGISRG 250
Cdd:COG0566 154 YNPKVVRASAGALFHVPVARVTNLADALEELKEAGFWVVGT-DLDG-------EASLYEVDLPGPVALVLGNEGKGLSRL 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 17555908 251 ILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLHHISLQNRTN 294
Cdd:COG0566 226 VLEACDELVRI-PMA---GGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
134-287 |
1.29e-36 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 127.50 E-value: 1.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 134 IFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPkSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVatcd 213
Cdd:cd18103 3 LILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSA-PLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIY---- 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17555908 214 pGAAEKAGisaKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRKdgsNVTSLNVSVVAGILLHHI 287
Cdd:cd18103 78 -GADGEAE---KSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKI-PMAG---KVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
43-290 |
2.99e-36 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 129.77 E-value: 2.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 43 EALFGLHSVLEAIRSGKRdfhsVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASAL 122
Cdd:TIGR00186 2 EYLYGKNAVLEALLNQQR----VFILKGLE-----SKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 123 QFSNFE--PKTVS-------IFVDKVLDPGNLGAIGRSAWYFGADGLgLVKGRGPKSITPAMIKSSCGALEHLPVQQFLN 193
Cdd:TIGR00186 73 LYKDLNdlYKTAKskkqpflLILDEITDPHNLGAILRTAEAFGVDGV-ILPKRRSAPLNSTVVKTSSGAVEYVPLARVTN 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 194 FNEFRDKIKAAGGELVATcdPGAAEKAGISAKSLdqwtpeKPVGIVLGDEGVGISRGILNLCDTVISISPVRKdgsnVTS 273
Cdd:TIGR00186 152 LSRTITKLKESGFWTVGT--DLDAQDTLYQVKLT------KPLALVVGNEGEGVSRLIKENCDFLIKIPMAGK----VDS 219
|
250
....*....|....*..
gi 17555908 274 LNVSVVAGILLHHISLQ 290
Cdd:TIGR00186 220 LNVSVAAGILLFEIKRQ 236
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
132-285 |
1.93e-32 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 116.86 E-value: 1.93e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVAT 211
Cdd:pfam00588 2 LVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVAT 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17555908 212 cDPGaaekagisAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRKDgsnVTSLNVSVVAGILLH 285
Cdd:pfam00588 82 -SLG--------GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRI-PMSGD---VESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
134-287 |
2.14e-32 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 116.76 E-value: 2.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 134 IFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPkSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcD 213
Cdd:cd18095 3 LVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVD-PYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAA-D 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17555908 214 PGAaekagisAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLHHI 287
Cdd:cd18095 81 LDG-------GSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTI-PMS---GGVESLNVAVAAAILLYEL 143
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
134-287 |
9.79e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 86.13 E-value: 9.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 134 IFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGpKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcd 213
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTA-DIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGL-- 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17555908 214 pgAAEKAGISAKSLDQWTPeKPVGIVLGDEGVGISRGILNLCDTVISIsPVRKdgsNVTSLNVSVVAGILLHHI 287
Cdd:cd18082 79 --ELTDGSIPLSEFKFKKP-KKIALIFGNERSGLSPELLALCDYTVHI-PMSG---KNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
132-287 |
2.08e-18 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 79.51 E-value: 2.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGR----GPKSItpamiKSSCGALEHLPVQQfLNFNEFRDKIKAAgge 207
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTvdpyNPKVV-----QASMGSIFRVQIHY-TDLPALLAELKKA--- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 208 lvatcDPGAAekAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISISPvrkDGSNVTSLNVSVVAGILLHHI 287
Cdd:cd18109 72 -----FPVYG--ADLDGENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPR---YGKGAESLNVAVATAILLSEF 141
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
130-290 |
2.46e-18 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 80.20 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 130 KTVSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSITPamiKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELV 209
Cdd:cd18092 15 RDLTVVLENVHDPHNASAVLRTCDAFGVQDVHVIEPKNKFKKNR---GVAMGADKWLDVHRHDSTEECLAALKEQGYRIV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 210 ATCDpgaaekaGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdGSnVTSLNVSVVAGILLHHISL 289
Cdd:cd18092 92 ATSL-------SPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYI-PMY--GF-VESLNVSVAAAIILYELQR 160
|
.
gi 17555908 290 Q 290
Cdd:cd18092 161 Q 161
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
43-290 |
4.95e-17 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 78.47 E-value: 4.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 43 EALFGLHSVlEAI--RSGKRdFHSVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICM--- 117
Cdd:PRK11181 3 EIIYGIHAV-QALleRAPER-FIEVFVLKGRE-----DKRLLPLINELEAQGIVIQLANRQTLDEKAEGAVHQGIIArvk 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 118 --------DASALqFSNFEPKTVSIfVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGpKSITPAMIKSSCGALEHLPVQ 189
Cdd:PRK11181 76 pgrqlqenDLPDL-LASLEQPFLLI-LDGVTDPHNLGACLRSADAAGVHAVIVPKDRS-AQLNATAKKVACGAAETVPLI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 190 QFLNFNEFRDKIKAAGGELVATcdpgaaekAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdGS 269
Cdd:PRK11181 153 RVTNLARTMRMLQEKNIWIVGT--------AGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISI-PMA--GS 221
|
250 260
....*....|....*....|.
gi 17555908 270 nVTSLNVSVVAGILLHHISLQ 290
Cdd:PRK11181 222 -VSSLNVSVATGICLFEAVRQ 241
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
144-286 |
1.58e-16 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 74.56 E-value: 1.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 144 NLGAIGRSAWYFGADGLGLVkGRGPKSITPAMiksscGALEHLPVQQFLNFNEFRDKIKAAGGELVaTCDPGAaekagiS 223
Cdd:cd18096 13 NIGTIVRSANAFGVKEVHLV-GRRKFNPFGAM-----GTDRHVKFRHFDTLAEAKEYLKERGIRLV-GVEIVP------G 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17555908 224 AKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIspvRKDGSNVTSLNVSVVAGILLHH 286
Cdd:cd18096 80 AEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYI---PQYGSGTASLNVSVAASIVLHH 139
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
137-287 |
1.63e-16 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 74.73 E-value: 1.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 137 DKVLDPGNLGAIGRSAWYFGADGLgLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRD-----KIKAAGGELVAT 211
Cdd:cd18107 6 DRPTSPGNLGTIIRSADALGAHGL-VVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDwvearKARGTPLQLVGT 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17555908 212 CDPGAAEkagisaksLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdGSnVTSLNVSVVAGILLHHI 287
Cdd:cd18107 85 DEHGDHQ--------IADHDFTRPTLLLIGNETAGLSAAWRELCDETVSI-PMA--GS-ASSLNAACAASIFLYEA 148
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
132-287 |
2.03e-14 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 69.13 E-value: 2.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAwyfgaDGLGLVK----GRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGE 207
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTA-----DAAGVEKiylcGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 208 LVAtcdpgaAEKAGiSAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLHHI 287
Cdd:cd18097 76 IIA------LETTE-NSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEI-PMF---GRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
142-291 |
4.01e-14 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 68.38 E-value: 4.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 142 PGNLGAIGRSAWYFGADGLGLVKGRGPKSiTPAMIKSSCGALEHLPV-----QQFLNFnefrdkIKAAGGELVATcDPGA 216
Cdd:cd18104 11 PGNLGAILRSADAAGADAVILCDPKTDLF-NPNVIRASLGAVFTLPVaeassEETLAW------LKENKIRILAT-TPKA 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17555908 217 aekagisAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLHHISLQN 291
Cdd:cd18104 83 -------EKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRI-PMA---GQADSLNVSVAAAILLYEALRQR 146
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
100-292 |
7.92e-13 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 67.88 E-value: 7.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 100 DDQLDRLTEFQLHNGIC--------MDASALqFSNFEPKTVSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSi 171
Cdd:PRK10864 160 EAELTKASGTEHHGGVCflikkrngTDVQQW-LAQAGAQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLES- 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 172 tPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcdpgaaekAGISAKSLDQWT-PEKPVgIVLGDEGVGISRG 250
Cdd:PRK10864 238 -GAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTT--------SSHKGTPLFKASlPAKMV-LVLGQEYDGLSDA 307
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 17555908 251 ILNLCDTVISIspvrkDGS-NVTSLNVSVVAGILLHHISLQNR 292
Cdd:PRK10864 308 ARQQGDLSVSI-----DGTgNVESLNVSVATGVLLAEWWRQNK 345
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
45-123 |
5.18e-12 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 60.33 E-value: 5.18e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17555908 45 LFGLHSVLEAIRSGKRdFHSVFLKKAVEnradsDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASALQ 123
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEGRR-----DPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKPYE 74
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
132-284 |
9.40e-10 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 56.11 E-value: 9.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 132 VSIFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGR----GPKsitpaMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGE 207
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCvdpwEPK-----VLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 208 LVatcdpgaAEKAGISAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCD----TVISIsPVRKdgsNVTSLNVSVVAGIL 283
Cdd:cd18106 76 FL-------ADNNLPVQPYDSIDYCSGPIVLVIGGETHGVSPEAYKLAHstggSRVHI-PLAN---GVDSLNSAVAASIL 144
|
.
gi 17555908 284 L 284
Cdd:cd18106 145 L 145
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
45-121 |
1.54e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 53.31 E-value: 1.54e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17555908 45 LFGLHSVLEAIRSGKRdFHSVFLKKavenraDSDARIKEILSRIDELGIQKTLLTDDQLDRLTEFQLHNGICMDASA 121
Cdd:smart00967 1 IEGRHAVEEALKSGRR-IKELYLTE------GRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
134-285 |
2.19e-07 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 49.40 E-value: 2.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 134 IFVDKVLDPGNLGAIGRSAWYFGADGLGLVKGRGPKSITPAMIKSSCGALEHLPV-----QQFLNFNEFRDKikaaggeL 208
Cdd:cd18108 3 VVLDGVRIVGNIGAIVRTSLALGAAGIVLVDSDLATVADRRLLRASRGYVFSLPVvladrEEAVAFLRDNDI-------P 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17555908 209 VATCDPGAaekaGISAKSLdQWTPEkPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLH 285
Cdd:cd18108 76 LMTLDADG----DVPVKEL-GDRPD-RLALVFGSEKGGPSGLFEEAAAGTVSI-PMS---SSTESLNVSVSAGIALH 142
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
142-291 |
1.04e-06 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 47.45 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 142 PGNLGAIGRSAWYFGAdGLGLVKGRGpKSITPAMIKSScGA--LEHLPVQQFLNFNEFRDKIKaaGGELVAtcdpgaAEK 219
Cdd:cd18094 10 PQNTGNIARTCAATGA-RLHLIEPLG-FSLDDKRLKRA-GLdyWDHVDLTVHDSWEAFLEALP--PGRLFL------FTT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17555908 220 AGisAKSLDQWTPEKPVGIVLGDEGVGISRGILNLC-DTVISIsPVRkdgSNVTSLNVSVVAGILLHHISLQN 291
Cdd:cd18094 79 KG--TKPYTDFDFKPGDYLVFGRESTGLPEEILDAFpDRRLRI-PMR---PKVRSLNLSNSVAIVLYEALRQL 145
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
141-285 |
9.92e-05 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 41.48 E-value: 9.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 141 DPGNLGAIGRSAWYFGADGLGLV----KGRGPKSITpamikssCGALEHLPVQQFLNFNEFRDKiKAAGGELVATcdpga 216
Cdd:cd18098 10 TPKNVGTLWRAAGCLGASFVFTIgaryKRRKQSTDT-------SKAWRHIPLFHYDDLEDLAEP-LPFGAVLVAV----- 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 217 aeKAGISAKSLDQWT-PEKPVGIvLGDEGVGISRGILNLCDTVISIsPVRkdgsnvTSLNVSVVAGILLH 285
Cdd:cd18098 77 --ELTEGATPLPDFKhPDRAVYL-LGPEDGGLPQEVLARCHHVVYL-PTR------GSLNVAVAGSIVLY 136
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
136-285 |
2.83e-04 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 40.21 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 136 VDKvldPGNLGAIGRSAWYFGADGLglVKGRGPKSITPAMIKSSCGALEHLPVQQ--FLNFNEFRDKIKAAGGELVAtcd 213
Cdd:cd18091 8 IDK---PPNLGGLCRTCEIFGVSKL--VLPNLAVVEDKQFKALSVSAEKWLPIEEvkPEDLLPYLKEKKQEGYTIVG--- 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17555908 214 pgaAEKAGiSAKSLDQWTPEKPVGIVLGDEGVGISRGILNLCDTVISIsPVRkdgSNVTSLNVSVVAGILLH 285
Cdd:cd18091 80 ---LEQTA-NSVSLHDFQFPKKTVLVLGNEKEGIPAELLSLLDVCVEI-PQL---GVIRSLNVHVSGAIAIY 143
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
134-285 |
7.91e-04 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 39.98 E-value: 7.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17555908 134 IFVDKVLDPGNLGAIGRSAwyfGADGLGLVKGRGPKSITPAMIKSSCGALEHLPVQQFLNFNEFRDKIKAAGGELVATcd 213
Cdd:PRK11081 22 VCMEQVHKPHNVSAIIRTA---DAVGVHEVHAVWPGSRMRTMGSTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILAT-- 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17555908 214 pgaaekaGISAKSLD----QWTpeKPVGIVLGDEGVGISRGILNLCDTVISISPVrkdgSNVTSLNVSVVAGILLH 285
Cdd:PRK11081 97 -------HLSDTAVDfreiDYT--RPTCILMGQEKTGISQEALALADQDIIIPMI----GMVQSLNVSVASALILY 159
|
|
| |
